Mutagenetix > Incidental Mutation

Incidental Mutation 'R2062:Nbea'

228737

Institutional Source

Beutler Lab

Gene Symbol

Nbea

Ensembl Gene

ENSMUSG00000027799

Gene Name

neurobeachin

Synonyms

MMRRC Submission

040067-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R2062 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

55532616-56091122 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 55993578 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000029374 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000029374]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000029374

SMART Domains

Protein: ENSMUSP00000029374
Gene: ENSMUSG00000027799

Domain	Start	End	E-Value	Type
low complexity region	19	40	N/A	INTRINSIC
Pfam:Laminin_G_3	228	393	2.8e-13	PFAM
Pfam:DUF4704	462	733	4e-113	PFAM
low complexity region	792	802	N/A	INTRINSIC
low complexity region	964	969	N/A	INTRINSIC
low complexity region	1781	1790	N/A	INTRINSIC
low complexity region	1791	1807	N/A	INTRINSIC
low complexity region	1835	1845	N/A	INTRINSIC
Pfam:DUF1088	1956	2122	3.5e-91	PFAM
Pfam:PH_BEACH	2148	2245	2.6e-32	PFAM
Beach	2276	2553	1.3e-205	SMART
WD40	2659	2696	2.12e2	SMART
WD40	2699	2742	2.22e0	SMART
WD40	2759	2798	9.21e0	SMART
WD40	2842	2880	2.88e-1	SMART
WD40	2883	2922	8.91e-1	SMART

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.8%
20x: 94.0%

Validation Efficiency

99% (84/85)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
PHENOTYPE: Mice homozygous for a gene trapped allele or transgene insertion die shortly after birth, are cyanotic, and exhibit no response to tactile stimuli, no spontaneous movement, and impaired CNS synaptic transmission. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Gene trapped(3) Transgenic(1)

Other mutations in this stock

Total: 82 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933436I01Rik	T	A	X: 66,964,308 (GRCm39)	I184L	probably benign	Het
A2ml1	A	T	6: 128,529,271 (GRCm39)	M957K	probably benign	Het
Adam7	C	A	14: 68,742,610 (GRCm39)	V668F	probably benign	Het
Adcy7	T	G	8: 89,038,902 (GRCm39)	L306R	probably damaging	Het
Akt3	A	G	1: 176,930,551 (GRCm39)	S136P	possibly damaging	Het
Alox12e	G	A	11: 70,206,828 (GRCm39)	R620W	probably damaging	Het
Amy2a1	T	C	3: 113,324,217 (GRCm39)	I108V	probably benign	Het
Ano7	T	C	1: 93,318,035 (GRCm39)	V249A	probably benign	Het
Aox1	T	C	1: 58,098,351 (GRCm39)		probably null	Het
Asah2	A	T	19: 32,002,274 (GRCm39)	V290E	probably damaging	Het
Ascc2	A	T	11: 4,631,496 (GRCm39)	M646L	probably benign	Het
Atxn2l	T	A	7: 126,095,038 (GRCm39)	K421N	probably damaging	Het
Cars2	T	C	8: 11,597,747 (GRCm39)	I110V	probably damaging	Het
Ccdc74a	A	G	16: 17,467,890 (GRCm39)	N249S	probably benign	Het
Cenpe	T	C	3: 134,928,082 (GRCm39)		probably benign	Het
Clptm1l	C	T	13: 73,755,842 (GRCm39)	Q153*	probably null	Het
Cnep1r1	G	T	8: 88,845,445 (GRCm39)		probably benign	Het
Cyp2d37-ps	C	T	15: 82,574,289 (GRCm39)		noncoding transcript	Het
Cyp3a25	A	G	5: 145,923,779 (GRCm39)		probably benign	Het
Dis3l	G	T	9: 64,246,855 (GRCm39)	Q67K	probably benign	Het
Dnah1	A	G	14: 30,993,086 (GRCm39)	V2936A	probably damaging	Het
Dnah5	C	T	15: 28,366,416 (GRCm39)	R2710C	probably damaging	Het
Dtx2	C	T	5: 136,059,431 (GRCm39)	S493F	probably damaging	Het
Dvl3	G	A	16: 20,345,101 (GRCm39)	S361N	probably benign	Het
Ehd1	T	C	19: 6,348,108 (GRCm39)	L362P	probably benign	Het
Eif2ak3	T	C	6: 70,881,181 (GRCm39)	V1085A	probably benign	Het
Eif3b	T	C	5: 140,412,208 (GRCm39)	Y226H	probably damaging	Het
Endov	T	C	11: 119,390,408 (GRCm39)	F12S	probably damaging	Het
Ercc1	A	G	7: 19,088,295 (GRCm39)	*37W	probably null	Het
Evi2a	G	A	11: 79,418,593 (GRCm39)	Q6*	probably null	Het
Faah	C	T	4: 115,855,770 (GRCm39)	V552M	probably damaging	Het
Fat1	T	A	8: 45,477,369 (GRCm39)	N2138K	probably damaging	Het
Fat1	T	A	8: 45,479,741 (GRCm39)	V2929E	probably damaging	Het
Gm2959	A	G	14: 42,235,658 (GRCm39)		noncoding transcript	Het
Gm6327	A	T	16: 12,578,979 (GRCm39)		noncoding transcript	Het
Gm9912	T	C	3: 148,890,795 (GRCm39)	T113A	unknown	Het
Gtf2f2	A	G	14: 76,155,136 (GRCm39)	S142P	possibly damaging	Het
Hspg2	A	T	4: 137,286,678 (GRCm39)	T3666S	possibly damaging	Het
Htt	C	T	5: 34,983,326 (GRCm39)	T975I	probably benign	Het
Il2rg	A	G	X: 100,311,416 (GRCm39)	L57P	possibly damaging	Het
Iqgap1	G	A	7: 80,373,727 (GRCm39)	Q1421*	probably null	Het
Itga3	T	A	11: 94,944,902 (GRCm39)	Q802L	possibly damaging	Het
Lonp2	A	G	8: 87,392,403 (GRCm39)	T490A	probably damaging	Het
Lztr1	T	C	16: 17,327,534 (GRCm39)	V79A	probably damaging	Het
Mast4	C	T	13: 102,895,601 (GRCm39)	E736K	probably benign	Het
Mpp4	G	A	1: 59,182,941 (GRCm39)	P322L	possibly damaging	Het
Mrto4	T	C	4: 139,076,334 (GRCm39)	K86E	probably benign	Het
Myof	A	G	19: 37,904,194 (GRCm39)	V2A	possibly damaging	Het
Naf1	A	G	8: 67,340,432 (GRCm39)	D414G	probably damaging	Het
Nav3	G	A	10: 109,555,882 (GRCm39)	T1683M	probably damaging	Het
Nebl	A	T	2: 17,401,932 (GRCm39)	M427K	probably benign	Het
Ngdn	T	C	14: 55,259,564 (GRCm39)	V205A	possibly damaging	Het
Nup133	C	A	8: 124,641,314 (GRCm39)	D869Y	probably damaging	Het
Oas1g	T	C	5: 121,023,946 (GRCm39)	E121G	probably damaging	Het
Or10j3b	T	C	1: 173,043,277 (GRCm39)	F20L	probably benign	Het
Or2ab1	A	G	11: 58,488,396 (GRCm39)	N58S	probably damaging	Het
Or2w3	G	T	11: 58,556,808 (GRCm39)	C141F	probably damaging	Het
Or5m9	A	G	2: 85,877,299 (GRCm39)	T158A	probably damaging	Het
Or6c205	T	A	10: 129,087,001 (GRCm39)	Y199*	probably null	Het
Park7	T	C	4: 150,989,732 (GRCm39)	N76S	probably benign	Het
Pcdh8	A	T	14: 80,005,651 (GRCm39)	S912R	probably damaging	Het
Pkhd1	A	G	1: 20,271,559 (GRCm39)	I2998T	probably damaging	Het
Plxnb3	T	A	X: 72,815,357 (GRCm39)	Y1845*	probably null	Het
Ppard	A	G	17: 28,518,663 (GRCm39)	H388R	probably damaging	Het
Psma1	A	G	7: 113,869,001 (GRCm39)	S142P	possibly damaging	Het
Pth2r	T	C	1: 65,382,721 (GRCm39)	I158T	probably damaging	Het
Rbl2	C	A	8: 91,833,367 (GRCm39)	P714Q	probably damaging	Het
Rexo2	A	T	9: 48,385,813 (GRCm39)	S104T	possibly damaging	Het
Sema5a	T	C	15: 32,609,363 (GRCm39)		probably benign	Het
Spmip10	C	T	18: 56,721,535 (GRCm39)	Q25*	probably null	Het
Sun2	A	G	15: 79,622,852 (GRCm39)	L109P	probably damaging	Het
Tdg	A	G	10: 82,477,368 (GRCm39)	T116A	probably benign	Het
Terb1	A	T	8: 105,195,380 (GRCm39)	M587K	possibly damaging	Het
Tmcc1	C	T	6: 116,020,019 (GRCm39)	V118M	probably benign	Het
Tnfsf11	T	A	14: 78,516,362 (GRCm39)	N202I	probably damaging	Het
Togaram2	T	C	17: 72,023,360 (GRCm39)	S759P	probably benign	Het
Ttc7b	G	A	12: 100,291,948 (GRCm39)	A208V	probably damaging	Het
Tti2	T	C	8: 31,644,338 (GRCm39)		probably benign	Het
Wnk1	T	C	6: 119,905,118 (GRCm39)		probably null	Het
Zfyve26	T	C	12: 79,330,806 (GRCm39)		probably null	Het
Zfyve28	T	C	5: 34,391,681 (GRCm39)	M157V	probably null	Het
Zgrf1	T	C	3: 127,406,999 (GRCm39)	C1589R	probably damaging	Het

Other mutations in Nbea

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00540:Nbea	APN	3	55,535,914 (GRCm39)	missense	probably damaging	1.00
IGL00541:Nbea	APN	3	55,875,510 (GRCm39)	missense	probably benign	0.02
IGL00584:Nbea	APN	3	55,989,869 (GRCm39)	missense	probably damaging	0.98
IGL00648:Nbea	APN	3	55,916,681 (GRCm39)	missense	probably damaging	0.98
IGL00785:Nbea	APN	3	55,862,814 (GRCm39)	missense	probably benign
IGL00899:Nbea	APN	3	55,550,266 (GRCm39)	missense	probably benign	0.32
IGL00955:Nbea	APN	3	55,912,893 (GRCm39)	missense	possibly damaging	0.45
IGL01296:Nbea	APN	3	55,938,957 (GRCm39)	missense	probably benign	0.04
IGL01299:Nbea	APN	3	55,598,315 (GRCm39)	missense	probably damaging	1.00
IGL01393:Nbea	APN	3	55,912,729 (GRCm39)	missense	probably benign	0.02
IGL01550:Nbea	APN	3	55,712,669 (GRCm39)	missense	possibly damaging	0.93
IGL02023:Nbea	APN	3	55,588,437 (GRCm39)	missense	probably damaging	1.00
IGL02034:Nbea	APN	3	55,875,577 (GRCm39)	missense	probably damaging	1.00
IGL02061:Nbea	APN	3	55,625,308 (GRCm39)	missense	possibly damaging	0.54
IGL02082:Nbea	APN	3	55,875,588 (GRCm39)	missense	possibly damaging	0.88
IGL02113:Nbea	APN	3	55,899,913 (GRCm39)	missense	probably benign
IGL02188:Nbea	APN	3	55,891,258 (GRCm39)	missense	probably benign	0.00
IGL02319:Nbea	APN	3	55,893,159 (GRCm39)	missense	probably damaging	1.00
IGL02406:Nbea	APN	3	55,993,687 (GRCm39)	missense	probably benign	0.02
IGL02494:Nbea	APN	3	55,712,772 (GRCm39)	missense	probably benign	0.02
IGL02550:Nbea	APN	3	55,926,835 (GRCm39)	missense	probably damaging	0.98
IGL02706:Nbea	APN	3	55,944,699 (GRCm39)	missense	probably damaging	1.00
IGL02718:Nbea	APN	3	55,539,483 (GRCm39)	nonsense	probably null
IGL02822:Nbea	APN	3	55,926,868 (GRCm39)	missense	possibly damaging	0.93
IGL02885:Nbea	APN	3	55,539,407 (GRCm39)	missense	probably benign	0.01
IGL03000:Nbea	APN	3	55,912,048 (GRCm39)	missense	possibly damaging	0.94
IGL03081:Nbea	APN	3	55,987,339 (GRCm39)	missense	probably damaging	1.00
IGL03091:Nbea	APN	3	55,992,725 (GRCm39)	missense	probably damaging	1.00
IGL03368:Nbea	APN	3	55,987,351 (GRCm39)	missense	probably damaging	0.98
Neches	UTSW	3	55,860,455 (GRCm39)	critical splice donor site	probably null
scotland	UTSW	3	55,534,329 (GRCm39)	missense	probably damaging	1.00
Wales	UTSW	3	55,998,540 (GRCm39)	missense	probably damaging	1.00
FR4340:Nbea	UTSW	3	55,916,633 (GRCm39)	critical splice donor site	probably benign
G4846:Nbea	UTSW	3	55,994,918 (GRCm39)	missense	probably damaging	0.98
IGL02835:Nbea	UTSW	3	55,625,290 (GRCm39)	missense	possibly damaging	0.88
LCD18:Nbea	UTSW	3	55,608,948 (GRCm39)	intron	probably benign
R0087:Nbea	UTSW	3	55,998,444 (GRCm39)	missense	possibly damaging	0.92
R0220:Nbea	UTSW	3	55,912,724 (GRCm39)	missense	probably benign	0.30
R0324:Nbea	UTSW	3	55,965,369 (GRCm39)	critical splice donor site	probably null
R0330:Nbea	UTSW	3	55,550,238 (GRCm39)	missense	probably benign	0.27
R0391:Nbea	UTSW	3	55,944,698 (GRCm39)	missense	probably damaging	1.00
R0394:Nbea	UTSW	3	55,937,328 (GRCm39)	missense	probably damaging	1.00
R0419:Nbea	UTSW	3	55,726,715 (GRCm39)	missense	probably benign	0.05
R0503:Nbea	UTSW	3	55,550,257 (GRCm39)	missense	possibly damaging	0.79
R0521:Nbea	UTSW	3	55,915,689 (GRCm39)	missense	probably damaging	1.00
R0595:Nbea	UTSW	3	55,535,917 (GRCm39)	missense	probably benign	0.18
R0894:Nbea	UTSW	3	55,916,761 (GRCm39)	missense	possibly damaging	0.89
R1072:Nbea	UTSW	3	55,993,617 (GRCm39)	missense	possibly damaging	0.94
R1125:Nbea	UTSW	3	55,764,427 (GRCm39)	nonsense	probably null
R1169:Nbea	UTSW	3	55,875,744 (GRCm39)	missense	probably benign	0.00
R1241:Nbea	UTSW	3	55,965,461 (GRCm39)	missense	probably damaging	1.00
R1269:Nbea	UTSW	3	55,912,202 (GRCm39)	missense	probably benign	0.05
R1406:Nbea	UTSW	3	55,944,702 (GRCm39)	missense	probably benign	0.00
R1406:Nbea	UTSW	3	55,944,702 (GRCm39)	missense	probably benign	0.00
R1457:Nbea	UTSW	3	55,992,748 (GRCm39)	missense	probably damaging	1.00
R1482:Nbea	UTSW	3	55,987,414 (GRCm39)	missense	probably damaging	1.00
R1483:Nbea	UTSW	3	55,910,211 (GRCm39)	missense	probably benign	0.25
R1502:Nbea	UTSW	3	55,912,310 (GRCm39)	missense	probably benign	0.03
R1544:Nbea	UTSW	3	55,966,248 (GRCm39)	missense	probably damaging	0.99
R1629:Nbea	UTSW	3	55,910,312 (GRCm39)	missense	possibly damaging	0.52
R1647:Nbea	UTSW	3	55,537,650 (GRCm39)	missense	probably damaging	0.97
R1663:Nbea	UTSW	3	55,553,407 (GRCm39)	missense	possibly damaging	0.95
R1722:Nbea	UTSW	3	55,573,116 (GRCm39)	missense	probably damaging	1.00
R1757:Nbea	UTSW	3	55,537,610 (GRCm39)	missense	possibly damaging	0.83
R1771:Nbea	UTSW	3	55,841,940 (GRCm39)	missense	probably benign	0.00
R1796:Nbea	UTSW	3	55,551,129 (GRCm39)	missense	possibly damaging	0.48
R1844:Nbea	UTSW	3	55,989,857 (GRCm39)	missense	probably damaging	0.97
R1872:Nbea	UTSW	3	55,550,310 (GRCm39)	missense	probably benign	0.12
R1938:Nbea	UTSW	3	55,992,743 (GRCm39)	missense	probably damaging	1.00
R1940:Nbea	UTSW	3	55,860,521 (GRCm39)	missense	possibly damaging	0.78
R2066:Nbea	UTSW	3	55,875,567 (GRCm39)	missense	probably damaging	1.00
R2097:Nbea	UTSW	3	55,630,638 (GRCm39)	missense	probably damaging	0.96
R2181:Nbea	UTSW	3	55,937,360 (GRCm39)	missense	possibly damaging	0.92
R2274:Nbea	UTSW	3	55,895,506 (GRCm39)	splice site	probably null
R2345:Nbea	UTSW	3	55,992,700 (GRCm39)	missense	probably damaging	1.00
R2423:Nbea	UTSW	3	55,992,727 (GRCm39)	missense	probably damaging	1.00
R2434:Nbea	UTSW	3	55,554,881 (GRCm39)	missense	possibly damaging	0.91
R2880:Nbea	UTSW	3	55,554,779 (GRCm39)	missense	probably benign	0.04
R2881:Nbea	UTSW	3	55,554,779 (GRCm39)	missense	probably benign	0.04
R2940:Nbea	UTSW	3	55,842,045 (GRCm39)	missense	probably benign	0.24
R3500:Nbea	UTSW	3	55,588,431 (GRCm39)	missense	possibly damaging	0.88
R3765:Nbea	UTSW	3	55,912,970 (GRCm39)	missense	probably damaging	1.00
R3790:Nbea	UTSW	3	55,912,450 (GRCm39)	missense	probably benign
R3808:Nbea	UTSW	3	55,625,269 (GRCm39)	missense	probably benign	0.02
R3845:Nbea	UTSW	3	55,993,713 (GRCm39)	splice site	probably benign
R4182:Nbea	UTSW	3	55,915,848 (GRCm39)	missense	probably damaging	0.99
R4385:Nbea	UTSW	3	55,908,059 (GRCm39)	missense	possibly damaging	0.77
R4419:Nbea	UTSW	3	55,917,021 (GRCm39)	missense	probably damaging	1.00
R4426:Nbea	UTSW	3	55,989,800 (GRCm39)	missense	probably damaging	0.98
R4451:Nbea	UTSW	3	55,899,753 (GRCm39)	critical splice donor site	probably null
R4456:Nbea	UTSW	3	55,551,205 (GRCm39)	missense	probably benign	0.00
R4604:Nbea	UTSW	3	55,631,069 (GRCm39)	missense	probably benign	0.18
R4687:Nbea	UTSW	3	55,965,486 (GRCm39)	missense	probably damaging	1.00
R4758:Nbea	UTSW	3	55,912,824 (GRCm39)	missense	probably benign
R4840:Nbea	UTSW	3	55,618,091 (GRCm39)	missense	probably benign	0.37
R4888:Nbea	UTSW	3	55,912,776 (GRCm39)	missense	possibly damaging	0.61
R4954:Nbea	UTSW	3	55,943,379 (GRCm39)	missense	probably damaging	1.00
R4972:Nbea	UTSW	3	55,992,667 (GRCm39)	missense	probably damaging	0.99
R4980:Nbea	UTSW	3	55,860,466 (GRCm39)	missense	probably benign	0.00
R4980:Nbea	UTSW	3	55,554,772 (GRCm39)	splice site	probably null
R5104:Nbea	UTSW	3	55,987,348 (GRCm39)	missense	probably damaging	1.00
R5139:Nbea	UTSW	3	55,534,384 (GRCm39)	missense	possibly damaging	0.90
R5166:Nbea	UTSW	3	55,926,874 (GRCm39)	missense	probably damaging	1.00
R5347:Nbea	UTSW	3	55,948,297 (GRCm39)	missense	probably damaging	1.00
R5350:Nbea	UTSW	3	55,926,845 (GRCm39)	missense	probably damaging	1.00
R5418:Nbea	UTSW	3	55,553,410 (GRCm39)	missense	possibly damaging	0.86
R5586:Nbea	UTSW	3	55,539,392 (GRCm39)	missense	probably benign	0.08
R5627:Nbea	UTSW	3	55,899,766 (GRCm39)	missense	probably damaging	1.00
R5683:Nbea	UTSW	3	55,536,007 (GRCm39)	missense	possibly damaging	0.53
R5765:Nbea	UTSW	3	55,912,719 (GRCm39)	missense	probably benign	0.15
R5853:Nbea	UTSW	3	55,899,822 (GRCm39)	missense	probably damaging	1.00
R5858:Nbea	UTSW	3	55,860,455 (GRCm39)	critical splice donor site	probably null
R5955:Nbea	UTSW	3	55,588,404 (GRCm39)	missense	probably benign	0.00
R5976:Nbea	UTSW	3	55,761,268 (GRCm39)	missense	probably benign	0.30
R6039:Nbea	UTSW	3	55,912,538 (GRCm39)	missense	probably benign	0.00
R6039:Nbea	UTSW	3	55,912,538 (GRCm39)	missense	probably benign	0.00
R6043:Nbea	UTSW	3	55,693,896 (GRCm39)	missense	probably benign	0.32
R6122:Nbea	UTSW	3	55,937,317 (GRCm39)	missense	probably damaging	1.00
R6218:Nbea	UTSW	3	55,535,905 (GRCm39)	missense	probably damaging	0.97
R6331:Nbea	UTSW	3	55,908,037 (GRCm39)	missense	possibly damaging	0.94
R6334:Nbea	UTSW	3	55,944,570 (GRCm39)	missense	probably damaging	1.00
R6393:Nbea	UTSW	3	55,998,540 (GRCm39)	missense	probably damaging	1.00
R6411:Nbea	UTSW	3	55,712,778 (GRCm39)	missense	probably benign	0.01
R6457:Nbea	UTSW	3	55,907,990 (GRCm39)	missense	probably damaging	1.00
R6476:Nbea	UTSW	3	55,912,227 (GRCm39)	missense	probably benign	0.00
R6488:Nbea	UTSW	3	55,625,264 (GRCm39)	missense	probably damaging	0.99
R6700:Nbea	UTSW	3	55,989,869 (GRCm39)	missense	possibly damaging	0.89
R6702:Nbea	UTSW	3	55,912,923 (GRCm39)	missense	probably benign	0.06
R6752:Nbea	UTSW	3	55,944,640 (GRCm39)	missense	probably benign
R6752:Nbea	UTSW	3	55,875,730 (GRCm39)	missense	probably benign	0.02
R6804:Nbea	UTSW	3	55,994,874 (GRCm39)	missense	probably benign	0.37
R6901:Nbea	UTSW	3	55,926,836 (GRCm39)	missense	probably damaging	1.00
R6933:Nbea	UTSW	3	55,631,031 (GRCm39)	missense	possibly damaging	0.63
R7124:Nbea	UTSW	3	55,899,865 (GRCm39)	missense	probably damaging	1.00
R7211:Nbea	UTSW	3	55,912,322 (GRCm39)	missense	probably benign	0.05
R7308:Nbea	UTSW	3	55,998,452 (GRCm39)	missense	probably damaging	1.00
R7405:Nbea	UTSW	3	55,712,687 (GRCm39)	missense	possibly damaging	0.94
R7669:Nbea	UTSW	3	55,625,200 (GRCm39)	missense	probably damaging	1.00
R7762:Nbea	UTSW	3	55,557,126 (GRCm39)	missense	probably damaging	1.00
R7833:Nbea	UTSW	3	55,910,218 (GRCm39)	missense	probably damaging	1.00
R7885:Nbea	UTSW	3	55,573,110 (GRCm39)	missense	probably damaging	0.97
R7935:Nbea	UTSW	3	55,966,086 (GRCm39)	missense	probably damaging	1.00
R8050:Nbea	UTSW	3	55,895,402 (GRCm39)	missense	probably damaging	0.99
R8108:Nbea	UTSW	3	55,726,736 (GRCm39)	missense	probably benign	0.11
R8290:Nbea	UTSW	3	55,966,056 (GRCm39)	nonsense	probably null
R8314:Nbea	UTSW	3	55,916,672 (GRCm39)	missense	probably damaging	0.99
R8321:Nbea	UTSW	3	56,090,518 (GRCm39)	missense	possibly damaging	0.86
R8376:Nbea	UTSW	3	55,551,076 (GRCm39)	missense	possibly damaging	0.79
R8410:Nbea	UTSW	3	55,944,684 (GRCm39)	missense	probably damaging	1.00
R8556:Nbea	UTSW	3	55,554,807 (GRCm39)	missense	probably benign	0.25
R8753:Nbea	UTSW	3	55,534,329 (GRCm39)	missense	probably damaging	1.00
R8844:Nbea	UTSW	3	55,998,415 (GRCm39)	missense	probably damaging	0.97
R8884:Nbea	UTSW	3	55,712,720 (GRCm39)	missense	probably benign	0.00
R8886:Nbea	UTSW	3	55,966,148 (GRCm39)	missense	probably damaging	1.00
R8890:Nbea	UTSW	3	55,926,784 (GRCm39)	splice site	probably benign
R9004:Nbea	UTSW	3	55,910,359 (GRCm39)	missense	probably benign	0.01
R9022:Nbea	UTSW	3	55,551,110 (GRCm39)	missense	possibly damaging	0.79
R9080:Nbea	UTSW	3	55,912,516 (GRCm39)	nonsense	probably null
R9087:Nbea	UTSW	3	55,550,157 (GRCm39)	critical splice donor site	probably null
R9104:Nbea	UTSW	3	55,862,809 (GRCm39)	missense	probably benign
R9165:Nbea	UTSW	3	55,912,289 (GRCm39)	missense	probably benign	0.15
R9219:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9221:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9222:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9260:Nbea	UTSW	3	55,891,233 (GRCm39)	missense	possibly damaging	0.50
R9263:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9265:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9294:Nbea	UTSW	3	55,998,513 (GRCm39)	missense	probably benign	0.00
R9360:Nbea	UTSW	3	55,943,319 (GRCm39)	missense	possibly damaging	0.96
R9387:Nbea	UTSW	3	55,898,460 (GRCm39)	missense	probably benign	0.12
R9428:Nbea	UTSW	3	55,998,393 (GRCm39)	frame shift	probably null
R9435:Nbea	UTSW	3	55,943,309 (GRCm39)	missense	possibly damaging	0.63
R9507:Nbea	UTSW	3	55,573,011 (GRCm39)	missense	probably damaging	1.00
R9514:Nbea	UTSW	3	55,937,366 (GRCm39)	missense	probably damaging	1.00
R9516:Nbea	UTSW	3	55,937,366 (GRCm39)	missense	probably damaging	1.00
R9674:Nbea	UTSW	3	55,966,183 (GRCm39)	missense	probably damaging	1.00
R9688:Nbea	UTSW	3	55,557,165 (GRCm39)	missense	probably benign	0.42
R9709:Nbea	UTSW	3	55,693,879 (GRCm39)	nonsense	probably null
RF051:Nbea	UTSW	3	55,916,633 (GRCm39)	critical splice donor site	probably benign
X0018:Nbea	UTSW	3	55,943,469 (GRCm39)	missense	probably benign	0.39
Z1088:Nbea	UTSW	3	55,630,584 (GRCm39)	missense	probably benign	0.34
Z1177:Nbea	UTSW	3	55,938,971 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CAGACACTAGTAACCCTGTTCTCC -3'
(R):5'- CAGCCTGTAGAAATTCTTTGACTG -3'

Sequencing Primer
(F):5'- AGTAACCCTGTTCTCCCTCTAATAG -3'
(R):5'- GGGAAATTTGACCAGAATAACTTTG -3'

Posted On

2014-09-17