Incidental Mutation 'R2063:Polr1a'
| ID |
228843 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Polr1a
|
| Ensembl Gene |
ENSMUSG00000049553 |
| Gene Name |
polymerase (RNA) I polypeptide A |
| Synonyms |
RPA194, 3010014K16Rik, 194kDa, mRPA1, Rpo1-4 |
| MMRRC Submission |
040068-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R2063 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
71909053-71984935 bp(+) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to G
at 71936285 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000060858
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055296]
[ENSMUST00000206556]
|
| AlphaFold |
O35134 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000055296
|
| SMART Domains |
Protein: ENSMUSP00000060858
Gene: ENSMUSG00000049553
| Domain | Start | End | E-Value | Type |
|---|
|
RPOLA_N
|
302 |
649 |
8.97e-137 |
SMART |
|
Pfam:RNA_pol_Rpb1_4
|
846 |
958 |
1.3e-26 |
PFAM |
|
Pfam:RNA_pol_Rpb1_5
|
965 |
1669 |
7e-103 |
PFAM |
|
low complexity region
|
1698 |
1708 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205942
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206556
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206753
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206823
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis. [provided by RefSeq, May 2016]
|
| Allele List at MGI |
All alleles(18) : Gene trapped(18) |
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933436I01Rik |
T |
A |
X: 67,920,702 (GRCm38) |
I184L |
probably benign |
Het |
| 9530002B09Rik |
T |
A |
4: 122,689,322 (GRCm38) |
|
probably benign |
Het |
| Abca15 |
A |
T |
7: 120,360,904 (GRCm38) |
T637S |
possibly damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,561,469 (GRCm38) |
K1135R |
possibly damaging |
Het |
| Afap1l1 |
A |
T |
18: 61,739,122 (GRCm38) |
|
probably null |
Het |
| AI467606 |
A |
G |
7: 127,092,837 (GRCm38) |
S195G |
probably damaging |
Het |
| Alox12e |
G |
A |
11: 70,316,002 (GRCm38) |
R620W |
probably damaging |
Het |
| Ascc2 |
A |
T |
11: 4,681,496 (GRCm38) |
M646L |
probably benign |
Het |
| Ccnt1 |
A |
T |
15: 98,551,942 (GRCm38) |
H156Q |
probably benign |
Het |
| Cic |
T |
A |
7: 25,273,451 (GRCm38) |
V869E |
probably damaging |
Het |
| Cpsf2 |
A |
G |
12: 101,983,463 (GRCm38) |
D118G |
probably damaging |
Het |
| Csnk1g1 |
A |
G |
9: 66,002,230 (GRCm38) |
S210G |
probably damaging |
Het |
| Cyp2c40 |
T |
A |
19: 39,786,780 (GRCm38) |
M343L |
probably benign |
Het |
| Cyp4a12b |
A |
T |
4: 115,433,503 (GRCm38) |
D274V |
possibly damaging |
Het |
| Dnaaf3 |
T |
C |
7: 4,523,799 (GRCm38) |
I426M |
possibly damaging |
Het |
| Dnah3 |
C |
T |
7: 119,951,909 (GRCm38) |
M3062I |
probably damaging |
Het |
| Dtx2 |
C |
T |
5: 136,030,577 (GRCm38) |
S493F |
probably damaging |
Het |
| Elavl2 |
A |
T |
4: 91,253,450 (GRCm38) |
S278R |
possibly damaging |
Het |
| Emilin2 |
T |
C |
17: 71,274,955 (GRCm38) |
S259G |
probably benign |
Het |
| Endov |
T |
C |
11: 119,499,582 (GRCm38) |
F12S |
probably damaging |
Het |
| Faim2 |
G |
A |
15: 99,514,433 (GRCm38) |
T140I |
probably damaging |
Het |
| Fbxo21 |
T |
C |
5: 117,976,966 (GRCm38) |
S56P |
probably benign |
Het |
| Fgb |
C |
A |
3: 83,049,689 (GRCm38) |
D25Y |
probably benign |
Het |
| Foxj2 |
A |
T |
6: 122,840,241 (GRCm38) |
H509L |
probably benign |
Het |
| Fth1 |
T |
A |
19: 9,984,212 (GRCm38) |
L49Q |
probably damaging |
Het |
| Gbp11 |
C |
A |
5: 105,328,584 (GRCm38) |
E220* |
probably null |
Het |
| Gm12695 |
T |
C |
4: 96,769,726 (GRCm38) |
T69A |
probably benign |
Het |
| Gm1527 |
C |
A |
3: 28,926,647 (GRCm38) |
T632N |
probably benign |
Het |
| Gm4787 |
A |
T |
12: 81,378,920 (GRCm38) |
S155T |
probably benign |
Het |
| Gm9573 |
T |
A |
17: 35,621,405 (GRCm38) |
|
probably benign |
Het |
| Gtf2f2 |
A |
G |
14: 75,917,696 (GRCm38) |
S142P |
possibly damaging |
Het |
| Helb |
T |
C |
10: 120,105,766 (GRCm38) |
Y339C |
probably benign |
Het |
| Hs3st4 |
A |
G |
7: 124,397,013 (GRCm38) |
I301V |
probably benign |
Het |
| Hunk |
A |
G |
16: 90,493,480 (GRCm38) |
D382G |
probably damaging |
Het |
| Ifnb1 |
T |
A |
4: 88,522,759 (GRCm38) |
I6F |
possibly damaging |
Het |
| Il10 |
T |
C |
1: 131,020,033 (GRCm38) |
L41P |
probably damaging |
Het |
| Il2rg |
A |
G |
X: 101,267,810 (GRCm38) |
L57P |
possibly damaging |
Het |
| Invs |
T |
A |
4: 48,396,287 (GRCm38) |
L320Q |
probably damaging |
Het |
| Itpr3 |
G |
A |
17: 27,098,076 (GRCm38) |
M768I |
probably benign |
Het |
| Krt90 |
T |
C |
15: 101,558,359 (GRCm38) |
E263G |
probably benign |
Het |
| Lama2 |
C |
T |
10: 27,164,926 (GRCm38) |
C1467Y |
probably damaging |
Het |
| Med24 |
A |
G |
11: 98,715,646 (GRCm38) |
L330P |
probably damaging |
Het |
| Mrto4 |
T |
C |
4: 139,349,023 (GRCm38) |
K86E |
probably benign |
Het |
| Mtcl1 |
T |
C |
17: 66,346,355 (GRCm38) |
R1065G |
probably damaging |
Het |
| Mtmr14 |
G |
A |
6: 113,240,361 (GRCm38) |
G38D |
probably damaging |
Het |
| Mtus1 |
T |
C |
8: 41,082,708 (GRCm38) |
E657G |
probably damaging |
Het |
| Myo5c |
A |
T |
9: 75,281,868 (GRCm38) |
Q1020L |
probably benign |
Het |
| Nav1 |
C |
T |
1: 135,449,004 (GRCm38) |
R1694Q |
probably damaging |
Het |
| Nckap1 |
T |
C |
2: 80,570,150 (GRCm38) |
K69R |
probably damaging |
Het |
| Nlrp1b |
T |
C |
11: 71,161,086 (GRCm38) |
N1012D |
probably benign |
Het |
| Ntrk2 |
A |
C |
13: 58,859,297 (GRCm38) |
K238Q |
probably damaging |
Het |
| Oas1g |
T |
C |
5: 120,885,883 (GRCm38) |
E121G |
probably damaging |
Het |
| Olfr324 |
A |
G |
11: 58,597,570 (GRCm38) |
N58S |
probably damaging |
Het |
| Olfr667 |
T |
C |
7: 104,916,775 (GRCm38) |
N174D |
probably benign |
Het |
| Pcdh8 |
A |
T |
14: 79,768,211 (GRCm38) |
S912R |
probably damaging |
Het |
| Pfpl |
C |
T |
19: 12,429,873 (GRCm38) |
S496L |
probably damaging |
Het |
| Phc2 |
T |
C |
4: 128,747,136 (GRCm38) |
F672S |
probably damaging |
Het |
| Pkhd1l1 |
A |
T |
15: 44,550,752 (GRCm38) |
H2805L |
possibly damaging |
Het |
| Pla2g4a |
T |
C |
1: 149,840,676 (GRCm38) |
N678S |
possibly damaging |
Het |
| Plxnb3 |
T |
A |
X: 73,771,751 (GRCm38) |
Y1845* |
probably null |
Het |
| Prl3d3 |
A |
C |
13: 27,162,321 (GRCm38) |
E180D |
probably benign |
Het |
| Prl7a2 |
T |
A |
13: 27,660,887 (GRCm38) |
Y172F |
probably damaging |
Het |
| Prpf3 |
A |
T |
3: 95,844,239 (GRCm38) |
D383E |
probably benign |
Het |
| Psmc4 |
A |
T |
7: 28,048,897 (GRCm38) |
L73H |
probably damaging |
Het |
| Rapgef3 |
C |
A |
15: 97,766,961 (GRCm38) |
G7V |
probably damaging |
Het |
| Rasl12 |
G |
A |
9: 65,410,824 (GRCm38) |
G157R |
probably damaging |
Het |
| Rnf38 |
A |
C |
4: 44,149,098 (GRCm38) |
V83G |
probably damaging |
Het |
| Rnls |
A |
C |
19: 33,202,544 (GRCm38) |
S51A |
probably benign |
Het |
| Siglecf |
A |
G |
7: 43,352,380 (GRCm38) |
T205A |
possibly damaging |
Het |
| Skint1 |
T |
A |
4: 112,025,533 (GRCm38) |
V258D |
probably benign |
Het |
| Slc12a5 |
C |
T |
2: 164,997,147 (GRCm38) |
R1072W |
probably damaging |
Het |
| Spata13 |
GTTAGGCT |
GT |
14: 60,760,871 (GRCm38) |
|
probably benign |
Het |
| Specc1 |
T |
G |
11: 62,118,296 (GRCm38) |
S293A |
probably benign |
Het |
| Speer2 |
T |
G |
16: 69,860,497 (GRCm38) |
Q86P |
probably benign |
Het |
| Tbc1d15 |
T |
C |
10: 115,229,173 (GRCm38) |
D169G |
probably benign |
Het |
| Tbx20 |
C |
A |
9: 24,769,771 (GRCm38) |
E142* |
probably null |
Het |
| Tcp1 |
T |
A |
17: 12,920,812 (GRCm38) |
L199H |
probably damaging |
Het |
| Tex26 |
A |
T |
5: 149,439,739 (GRCm38) |
R5W |
probably damaging |
Het |
| Tg |
C |
A |
15: 66,828,553 (GRCm38) |
A120E |
probably damaging |
Het |
| Thrap3 |
T |
C |
4: 126,175,396 (GRCm38) |
Y654C |
possibly damaging |
Het |
| Tmem57 |
A |
T |
4: 134,828,279 (GRCm38) |
N294K |
possibly damaging |
Het |
| Troap |
T |
C |
15: 99,082,463 (GRCm38) |
L508P |
probably benign |
Het |
| Ubap2 |
C |
T |
4: 41,199,872 (GRCm38) |
A752T |
probably benign |
Het |
| Ush1c |
T |
C |
7: 46,229,481 (GRCm38) |
Y74C |
probably damaging |
Het |
| Vmn1r55 |
A |
G |
7: 5,147,049 (GRCm38) |
V125A |
possibly damaging |
Het |
| Vmn2r120 |
T |
A |
17: 57,524,553 (GRCm38) |
H412L |
possibly damaging |
Het |
| Vps54 |
C |
T |
11: 21,277,955 (GRCm38) |
T176I |
probably damaging |
Het |
| Wdr95 |
T |
C |
5: 149,579,162 (GRCm38) |
|
probably null |
Het |
| Zfp81 |
T |
C |
17: 33,335,304 (GRCm38) |
T179A |
probably benign |
Het |
|
| Other mutations in Polr1a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01363:Polr1a
|
APN |
6 |
71,948,486 (GRCm38) |
missense |
probably benign |
0.32 |
|
IGL01834:Polr1a
|
APN |
6 |
71,948,462 (GRCm38) |
missense |
probably benign |
|
|
IGL01902:Polr1a
|
APN |
6 |
71,963,748 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02101:Polr1a
|
APN |
6 |
71,950,802 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02325:Polr1a
|
APN |
6 |
71,920,657 (GRCm38) |
missense |
probably benign |
0.38 |
|
IGL02398:Polr1a
|
APN |
6 |
71,936,556 (GRCm38) |
splice site |
probably benign |
|
|
IGL02528:Polr1a
|
APN |
6 |
71,964,717 (GRCm38) |
missense |
probably benign |
|
|
IGL02555:Polr1a
|
APN |
6 |
71,920,457 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02613:Polr1a
|
APN |
6 |
71,967,320 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02693:Polr1a
|
APN |
6 |
71,963,846 (GRCm38) |
splice site |
probably benign |
|
|
IGL02892:Polr1a
|
APN |
6 |
71,931,696 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
IGL03059:Polr1a
|
APN |
6 |
71,936,512 (GRCm38) |
missense |
probably benign |
|
|
IGL03174:Polr1a
|
APN |
6 |
71,977,347 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
D4043:Polr1a
|
UTSW |
6 |
71,941,417 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0092:Polr1a
|
UTSW |
6 |
71,967,455 (GRCm38) |
splice site |
probably benign |
|
|
R0217:Polr1a
|
UTSW |
6 |
71,963,703 (GRCm38) |
missense |
probably benign |
0.19 |
|
R0267:Polr1a
|
UTSW |
6 |
71,974,139 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0329:Polr1a
|
UTSW |
6 |
71,966,416 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R0330:Polr1a
|
UTSW |
6 |
71,966,416 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R0352:Polr1a
|
UTSW |
6 |
71,920,763 (GRCm38) |
splice site |
probably benign |
|
|
R0411:Polr1a
|
UTSW |
6 |
71,978,421 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R0446:Polr1a
|
UTSW |
6 |
71,950,664 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0846:Polr1a
|
UTSW |
6 |
71,924,643 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1035:Polr1a
|
UTSW |
6 |
71,967,916 (GRCm38) |
missense |
probably benign |
|
|
R1294:Polr1a
|
UTSW |
6 |
71,912,902 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1460:Polr1a
|
UTSW |
6 |
71,941,384 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1657:Polr1a
|
UTSW |
6 |
71,941,535 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1846:Polr1a
|
UTSW |
6 |
71,976,188 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1862:Polr1a
|
UTSW |
6 |
71,909,203 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1865:Polr1a
|
UTSW |
6 |
71,966,524 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1903:Polr1a
|
UTSW |
6 |
71,967,914 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1937:Polr1a
|
UTSW |
6 |
71,936,552 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2071:Polr1a
|
UTSW |
6 |
71,976,074 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R2084:Polr1a
|
UTSW |
6 |
71,950,809 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R2377:Polr1a
|
UTSW |
6 |
71,972,826 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2410:Polr1a
|
UTSW |
6 |
71,974,882 (GRCm38) |
missense |
probably benign |
|
|
R3001:Polr1a
|
UTSW |
6 |
71,913,016 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3001:Polr1a
|
UTSW |
6 |
71,965,644 (GRCm38) |
missense |
probably benign |
0.02 |
|
R3002:Polr1a
|
UTSW |
6 |
71,965,644 (GRCm38) |
missense |
probably benign |
0.02 |
|
R3002:Polr1a
|
UTSW |
6 |
71,913,016 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3924:Polr1a
|
UTSW |
6 |
71,929,450 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4105:Polr1a
|
UTSW |
6 |
71,976,191 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4125:Polr1a
|
UTSW |
6 |
71,965,706 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4271:Polr1a
|
UTSW |
6 |
71,953,022 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4440:Polr1a
|
UTSW |
6 |
71,950,848 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4667:Polr1a
|
UTSW |
6 |
71,917,821 (GRCm38) |
missense |
probably benign |
0.30 |
|
R4769:Polr1a
|
UTSW |
6 |
71,950,868 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4801:Polr1a
|
UTSW |
6 |
71,976,070 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4802:Polr1a
|
UTSW |
6 |
71,976,070 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4828:Polr1a
|
UTSW |
6 |
71,966,401 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4911:Polr1a
|
UTSW |
6 |
71,909,229 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R5071:Polr1a
|
UTSW |
6 |
71,931,709 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R5165:Polr1a
|
UTSW |
6 |
71,967,925 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5223:Polr1a
|
UTSW |
6 |
71,967,907 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R5239:Polr1a
|
UTSW |
6 |
71,913,037 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5546:Polr1a
|
UTSW |
6 |
71,929,366 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R5599:Polr1a
|
UTSW |
6 |
71,967,362 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5696:Polr1a
|
UTSW |
6 |
71,929,426 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5850:Polr1a
|
UTSW |
6 |
71,926,683 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6274:Polr1a
|
UTSW |
6 |
71,954,890 (GRCm38) |
splice site |
probably null |
|
|
R6526:Polr1a
|
UTSW |
6 |
71,929,443 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R6578:Polr1a
|
UTSW |
6 |
71,976,041 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R6660:Polr1a
|
UTSW |
6 |
71,967,374 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6892:Polr1a
|
UTSW |
6 |
71,964,712 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R7274:Polr1a
|
UTSW |
6 |
71,920,516 (GRCm38) |
nonsense |
probably null |
|
|
R7291:Polr1a
|
UTSW |
6 |
71,941,456 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7311:Polr1a
|
UTSW |
6 |
71,950,879 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R7431:Polr1a
|
UTSW |
6 |
71,926,659 (GRCm38) |
missense |
probably benign |
0.14 |
|
R7479:Polr1a
|
UTSW |
6 |
71,936,297 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7607:Polr1a
|
UTSW |
6 |
71,913,021 (GRCm38) |
missense |
probably benign |
|
|
R7739:Polr1a
|
UTSW |
6 |
71,954,835 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7746:Polr1a
|
UTSW |
6 |
71,941,512 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7764:Polr1a
|
UTSW |
6 |
71,953,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7835:Polr1a
|
UTSW |
6 |
71,915,142 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8029:Polr1a
|
UTSW |
6 |
71,912,956 (GRCm38) |
nonsense |
probably null |
|
|
R8057:Polr1a
|
UTSW |
6 |
71,931,660 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8144:Polr1a
|
UTSW |
6 |
71,950,616 (GRCm38) |
missense |
probably benign |
|
|
R8170:Polr1a
|
UTSW |
6 |
71,920,749 (GRCm38) |
missense |
probably benign |
|
|
R8320:Polr1a
|
UTSW |
6 |
71,941,384 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8328:Polr1a
|
UTSW |
6 |
71,920,734 (GRCm38) |
missense |
probably benign |
|
|
R8331:Polr1a
|
UTSW |
6 |
71,976,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8362:Polr1a
|
UTSW |
6 |
71,964,667 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8511:Polr1a
|
UTSW |
6 |
71,920,520 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8709:Polr1a
|
UTSW |
6 |
71,974,848 (GRCm38) |
missense |
probably benign |
|
|
R8745:Polr1a
|
UTSW |
6 |
71,954,771 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8784:Polr1a
|
UTSW |
6 |
71,950,628 (GRCm38) |
missense |
probably benign |
|
|
R9055:Polr1a
|
UTSW |
6 |
71,915,069 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R9088:Polr1a
|
UTSW |
6 |
71,931,783 (GRCm38) |
missense |
probably benign |
0.26 |
|
R9211:Polr1a
|
UTSW |
6 |
71,966,537 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9228:Polr1a
|
UTSW |
6 |
71,954,771 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9240:Polr1a
|
UTSW |
6 |
71,963,677 (GRCm38) |
nonsense |
probably null |
|
|
R9267:Polr1a
|
UTSW |
6 |
71,965,558 (GRCm38) |
missense |
probably benign |
|
|
R9302:Polr1a
|
UTSW |
6 |
71,924,699 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9744:Polr1a
|
UTSW |
6 |
71,929,388 (GRCm38) |
missense |
probably benign |
0.05 |
|
| Predicted Primers |
|
| Posted On |
2014-09-17 |
Incidental Mutation