Mutagenetix > Incidental Mutation

Incidental Mutation 'R2124:Dnah7a'

229627

Institutional Source

Beutler Lab

Gene Symbol

Dnah7a

Ensembl Gene

ENSMUSG00000096141

Gene Name

dynein, axonemal, heavy chain 7A

Synonyms

Dnahc7, LOC381341, Dnahc7a

MMRRC Submission

040127-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.147) question?

Stock #

R2124 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

53436165-53745943 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 53536101 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 2647 (D2647E)

Ref Sequence

ENSEMBL: ENSMUSP00000092571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094964]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000094964
AA Change: D2647E

PolyPhen 2 Score 0.583 (Sensitivity: 0.88; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000092571
Gene: ENSMUSG00000096141
AA Change: D2647E

Domain	Start	End	E-Value	Type
low complexity region	2	15	N/A	INTRINSIC
coiled coil region	504	537	N/A	INTRINSIC
Pfam:DHC_N2	756	1165	3.1e-149	PFAM
AAA	1320	1459	2.46e-1	SMART
Blast:AAA	1601	1879	1e-87	BLAST
AAA	1968	2116	5.39e-2	SMART
Pfam:AAA_8	2303	2574	6.9e-75	PFAM
Pfam:MT	2586	2936	2.1e-55	PFAM
Pfam:AAA_9	2957	3182	1.3e-98	PFAM
Pfam:Dynein_heavy	3318	4020	2.3e-287	PFAM

Meta Mutation Damage Score

0.0821

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.2%

Validation Efficiency

98% (80/82)

Allele List at MGI

Other mutations in this stock

Total: 78 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933430I17Rik	T	A	4: 62,457,109 (GRCm39)	L143M	possibly damaging	Het
Abca13	T	C	11: 9,259,013 (GRCm39)		probably benign	Het
Abcg5	T	A	17: 84,978,575 (GRCm39)	E294D	probably benign	Het
Adgrg6	T	C	10: 14,342,930 (GRCm39)	D339G	probably damaging	Het
Ahctf1	C	A	1: 179,597,017 (GRCm39)	R43L	probably damaging	Het
Ambn	T	A	5: 88,608,617 (GRCm39)		probably benign	Het
Arap3	A	C	18: 38,106,403 (GRCm39)	L1480R	probably damaging	Het
Arhgef10	A	G	8: 14,984,820 (GRCm39)	D200G	probably damaging	Het
Aspg	G	A	12: 112,087,608 (GRCm39)	V8I	probably benign	Het
Aven	T	A	2: 112,455,541 (GRCm39)	W26R	probably damaging	Het
Car4	T	A	11: 84,854,911 (GRCm39)		probably benign	Het
Cd163	C	T	6: 124,295,815 (GRCm39)	R720C	probably damaging	Het
Cdh1	A	G	8: 107,390,842 (GRCm39)	I653V	probably benign	Het
Cdh3	A	T	8: 107,279,520 (GRCm39)	H712L	probably damaging	Het
Cdr2	T	C	7: 120,581,250 (GRCm39)	E9G	probably damaging	Het
Cfap47	T	C	X: 78,553,927 (GRCm39)	I267V	probably benign	Het
Chrnb2	T	C	3: 89,676,648 (GRCm39)		probably benign	Het
Col4a2	C	A	8: 11,466,070 (GRCm39)	P443Q	probably damaging	Het
Cyp2a12	A	G	7: 26,736,071 (GRCm39)	*493W	probably null	Het
Ddias	T	C	7: 92,507,464 (GRCm39)	Q817R	probably benign	Het
Ddx6	C	T	9: 44,535,816 (GRCm39)	Q182*	probably null	Het
Dhrs7	A	G	12: 72,699,951 (GRCm39)	I227T	probably damaging	Het
Dhx8	A	T	11: 101,653,071 (GRCm39)	M970L	probably damaging	Het
Dstyk	G	A	1: 132,380,857 (GRCm39)	G451R	possibly damaging	Het
Ednrb	T	A	14: 104,059,204 (GRCm39)	D274V	probably benign	Het
Efl1	C	T	7: 82,342,121 (GRCm39)	R510C	probably damaging	Het
Eif4g3	A	G	4: 137,912,053 (GRCm39)	E1409G	probably damaging	Het
Fam78b	G	A	1: 166,906,278 (GRCm39)	V146M	probably damaging	Het
Fcgbp	T	C	7: 27,791,444 (GRCm39)	Y902H	probably benign	Het
Fgf18	A	C	11: 33,068,003 (GRCm39)	F129C	probably damaging	Het
Gbp9	T	A	5: 105,242,409 (GRCm39)	D110V	probably damaging	Het
Gm10477	A	G	X: 55,570,192 (GRCm39)	K31E	probably damaging	Het
Gm10542	T	A	18: 44,334,355 (GRCm39)	W9R	probably null	Het
Gpaa1	A	G	15: 76,217,552 (GRCm39)	Y330C	probably damaging	Het
Hectd4	T	C	5: 121,456,702 (GRCm39)	L689P	probably damaging	Het
Hoxd3	C	A	2: 74,574,578 (GRCm39)	P75T	possibly damaging	Het
Ikbkb	A	G	8: 23,156,036 (GRCm39)	L570P	probably damaging	Het
Ikbkb	T	C	8: 23,157,233 (GRCm39)		probably benign	Het
Il1rap	A	T	16: 26,529,315 (GRCm39)	H379L	probably damaging	Het
Ints6l	T	A	X: 55,550,228 (GRCm39)	S718T	probably benign	Het
Jaml	T	A	9: 45,012,362 (GRCm39)	I283N	probably damaging	Het
Kidins220	G	A	12: 25,091,302 (GRCm39)		probably null	Het
Kif1b	T	C	4: 149,306,753 (GRCm39)	D869G	probably benign	Het
Loxl2	T	C	14: 69,929,859 (GRCm39)	Y746H	probably benign	Het
Ltbr	A	G	6: 125,286,440 (GRCm39)	S249P	probably benign	Het
Mageb5	A	G	X: 90,823,701 (GRCm39)	I226T	probably damaging	Het
Msantd2	C	T	9: 37,434,227 (GRCm39)	R357W	probably damaging	Het
Mtcl2	T	C	2: 156,875,245 (GRCm39)	E835G	probably damaging	Het
Neb	A	G	2: 52,154,076 (GRCm39)	F2345S	probably damaging	Het
Or7e173	T	G	9: 19,938,797 (GRCm39)	I146L	probably benign	Het
Pabpc4l	T	C	3: 46,401,276 (GRCm39)	T123A	probably benign	Het
Plekhg4	TAGTCGATGCCCGAGTC	TAGTC	8: 106,103,084 (GRCm39)		probably benign	Het
Prkdc	T	C	16: 15,537,297 (GRCm39)	V1716A	probably benign	Het
Prss37	G	A	6: 40,492,294 (GRCm39)	R186*	probably null	Het
Psg20	T	A	7: 18,414,947 (GRCm39)	Y316F	probably benign	Het
Rasgrp2	T	A	19: 6,454,425 (GRCm39)	M156K	probably benign	Het
Rims1	T	A	1: 22,474,732 (GRCm39)	R200*	probably null	Het
Rnf168	T	G	16: 32,097,036 (GRCm39)	L37R	probably damaging	Het
Sall3	C	T	18: 81,015,012 (GRCm39)	G972D	probably benign	Het
Sap18	T	A	14: 58,036,011 (GRCm39)	S66T	probably damaging	Het
Scamp5	C	A	9: 57,354,508 (GRCm39)	V49F	possibly damaging	Het
Sdk1	C	A	5: 142,170,943 (GRCm39)	D1935E	possibly damaging	Het
Setd2	A	G	9: 110,378,932 (GRCm39)	S632G	probably benign	Het
Syt16	T	A	12: 74,285,009 (GRCm39)	S401T	probably damaging	Het
Tas2r106	A	T	6: 131,655,317 (GRCm39)	L178H	probably damaging	Het
Tbcd	A	G	11: 121,494,146 (GRCm39)	Y983C	probably damaging	Het
Tenm3	A	G	8: 48,870,041 (GRCm39)		probably null	Het
Tll1	T	C	8: 64,538,591 (GRCm39)	E351G	probably benign	Het
Tmem44	T	A	16: 30,366,262 (GRCm39)	K55*	probably null	Het
Top2a	T	C	11: 98,895,054 (GRCm39)	I849V	probably benign	Het
Ttn	A	G	2: 76,624,792 (GRCm39)	V13516A	probably damaging	Het
Uxs1	A	G	1: 43,814,006 (GRCm39)	L77P	probably damaging	Het
Vmn2r121	A	T	X: 123,043,439 (GRCm39)		probably null	Het
Vmn2r84	A	C	10: 130,227,100 (GRCm39)	M246R	probably damaging	Het
Vps13b	T	A	15: 35,646,226 (GRCm39)	N1443K	probably benign	Het
Wfdc6b	C	T	2: 164,459,363 (GRCm39)	R142C	probably benign	Het
Zfp616	A	G	11: 73,973,869 (GRCm39)		probably null	Het
Zmym1	T	C	4: 126,943,363 (GRCm39)	T244A	probably benign	Het

Other mutations in Dnah7a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00479:Dnah7a	APN	1	53,458,843 (GRCm39)	missense	probably damaging	0.99
IGL00510:Dnah7a	APN	1	53,540,701 (GRCm39)	missense	probably damaging	1.00
IGL00545:Dnah7a	APN	1	53,496,905 (GRCm39)	missense	possibly damaging	0.87
IGL01320:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01322:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01357:Dnah7a	APN	1	53,701,540 (GRCm39)	missense	probably benign
IGL01417:Dnah7a	APN	1	53,623,759 (GRCm39)	missense	probably benign	0.01
IGL01508:Dnah7a	APN	1	53,666,231 (GRCm39)	missense	probably benign	0.00
IGL01511:Dnah7a	APN	1	53,458,754 (GRCm39)	missense	probably damaging	1.00
IGL01545:Dnah7a	APN	1	53,557,941 (GRCm39)	missense	probably benign
IGL01575:Dnah7a	APN	1	53,466,979 (GRCm39)	splice site	probably benign
IGL01667:Dnah7a	APN	1	53,586,451 (GRCm39)	missense	probably damaging	1.00
IGL01712:Dnah7a	APN	1	53,462,429 (GRCm39)	missense	probably benign	0.23
IGL01824:Dnah7a	APN	1	53,543,429 (GRCm39)	missense	probably benign
IGL01829:Dnah7a	APN	1	53,657,227 (GRCm39)	missense	possibly damaging	0.64
IGL01861:Dnah7a	APN	1	53,623,608 (GRCm39)	splice site	probably benign
IGL01861:Dnah7a	APN	1	53,679,508 (GRCm39)	missense	probably benign	0.01
IGL01984:Dnah7a	APN	1	53,741,174 (GRCm39)	splice site	probably null
IGL02056:Dnah7a	APN	1	53,543,501 (GRCm39)	missense	probably benign	0.17
IGL02069:Dnah7a	APN	1	53,601,053 (GRCm39)	splice site	probably benign
IGL02072:Dnah7a	APN	1	53,644,986 (GRCm39)	missense	probably damaging	1.00
IGL02110:Dnah7a	APN	1	53,450,739 (GRCm39)	missense	possibly damaging	0.52
IGL02120:Dnah7a	APN	1	53,534,876 (GRCm39)	missense	possibly damaging	0.46
IGL02128:Dnah7a	APN	1	53,476,672 (GRCm39)	missense	probably damaging	1.00
IGL02135:Dnah7a	APN	1	53,662,632 (GRCm39)	missense	probably benign	0.01
IGL02151:Dnah7a	APN	1	53,512,023 (GRCm39)	missense	probably benign	0.08
IGL02156:Dnah7a	APN	1	53,458,882 (GRCm39)	missense	probably benign	0.27
IGL02270:Dnah7a	APN	1	53,512,052 (GRCm39)	missense	possibly damaging	0.93
IGL02282:Dnah7a	APN	1	53,682,669 (GRCm39)	missense	possibly damaging	0.93
IGL02328:Dnah7a	APN	1	53,564,096 (GRCm39)	critical splice donor site	probably null
IGL02370:Dnah7a	APN	1	53,674,556 (GRCm39)	missense	probably benign	0.00
IGL02420:Dnah7a	APN	1	53,725,702 (GRCm39)	missense	probably benign
IGL02458:Dnah7a	APN	1	53,657,487 (GRCm39)	nonsense	probably null
IGL02489:Dnah7a	APN	1	53,686,481 (GRCm39)	missense	possibly damaging	0.94
IGL02554:Dnah7a	APN	1	53,657,205 (GRCm39)	missense	possibly damaging	0.93
IGL02578:Dnah7a	APN	1	53,472,074 (GRCm39)	missense	probably benign	0.00
IGL02646:Dnah7a	APN	1	53,564,194 (GRCm39)	missense	probably damaging	0.99
IGL02675:Dnah7a	APN	1	53,543,183 (GRCm39)	missense	possibly damaging	0.96
IGL02688:Dnah7a	APN	1	53,483,631 (GRCm39)	missense	possibly damaging	0.93
IGL02858:Dnah7a	APN	1	53,512,118 (GRCm39)	splice site	probably benign
IGL02874:Dnah7a	APN	1	53,644,973 (GRCm39)	missense	possibly damaging	0.70
IGL02887:Dnah7a	APN	1	53,561,519 (GRCm39)	missense	possibly damaging	0.46
IGL02894:Dnah7a	APN	1	53,616,487 (GRCm39)	missense	probably benign	0.27
IGL02926:Dnah7a	APN	1	53,535,109 (GRCm39)	missense	possibly damaging	0.64
IGL03113:Dnah7a	APN	1	53,472,163 (GRCm39)	missense	possibly damaging	0.64
IGL03156:Dnah7a	APN	1	53,644,983 (GRCm39)	missense	probably damaging	0.97
IGL03195:Dnah7a	APN	1	53,458,766 (GRCm39)	missense	probably damaging	1.00
IGL03209:Dnah7a	APN	1	53,725,773 (GRCm39)	splice site	probably benign
IGL03214:Dnah7a	APN	1	53,561,368 (GRCm39)	critical splice donor site	probably null
IGL03242:Dnah7a	APN	1	53,659,882 (GRCm39)	missense	probably benign	0.02
IGL03251:Dnah7a	APN	1	53,686,433 (GRCm39)	missense	probably benign
IGL03265:Dnah7a	APN	1	53,568,007 (GRCm39)	missense	probably benign
IGL03277:Dnah7a	APN	1	53,669,481 (GRCm39)	missense	probably benign	0.00
IGL03278:Dnah7a	APN	1	53,536,124 (GRCm39)	missense	probably benign	0.07
IGL03356:Dnah7a	APN	1	53,543,093 (GRCm39)	missense	probably benign	0.01
PIT4378001:Dnah7a	UTSW	1	53,570,362 (GRCm39)	missense	probably damaging	0.99
R0046:Dnah7a	UTSW	1	53,496,033 (GRCm39)	splice site	probably null
R0051:Dnah7a	UTSW	1	53,560,245 (GRCm39)	splice site	probably benign
R0082:Dnah7a	UTSW	1	53,557,867 (GRCm39)	missense	probably damaging	1.00
R0111:Dnah7a	UTSW	1	53,507,843 (GRCm39)	missense	probably benign	0.03
R0122:Dnah7a	UTSW	1	53,436,301 (GRCm39)	missense	probably damaging	1.00
R0245:Dnah7a	UTSW	1	53,540,685 (GRCm39)	missense	probably damaging	1.00
R0278:Dnah7a	UTSW	1	53,543,305 (GRCm39)	missense	probably benign	0.00
R0309:Dnah7a	UTSW	1	53,444,849 (GRCm39)	missense	probably damaging	0.97
R0334:Dnah7a	UTSW	1	53,472,213 (GRCm39)	missense	possibly damaging	0.61
R0392:Dnah7a	UTSW	1	53,543,357 (GRCm39)	missense	probably damaging	0.97
R0452:Dnah7a	UTSW	1	53,644,978 (GRCm39)	missense	probably benign	0.00
R0511:Dnah7a	UTSW	1	53,536,285 (GRCm39)	missense	probably benign
R0576:Dnah7a	UTSW	1	53,675,246 (GRCm39)	missense	probably benign	0.12
R0592:Dnah7a	UTSW	1	53,495,771 (GRCm39)	missense	possibly damaging	0.91
R0628:Dnah7a	UTSW	1	53,536,264 (GRCm39)	missense	probably benign	0.18
R0689:Dnah7a	UTSW	1	53,659,840 (GRCm39)	nonsense	probably null
R0735:Dnah7a	UTSW	1	53,583,670 (GRCm39)	missense	possibly damaging	0.70
R0800:Dnah7a	UTSW	1	53,604,855 (GRCm39)	missense	probably damaging	1.00
R0829:Dnah7a	UTSW	1	53,543,238 (GRCm39)	missense	probably benign	0.07
R0842:Dnah7a	UTSW	1	53,540,833 (GRCm39)	missense	possibly damaging	0.88
R0879:Dnah7a	UTSW	1	53,467,019 (GRCm39)	missense	possibly damaging	0.85
R1331:Dnah7a	UTSW	1	53,507,828 (GRCm39)	missense	probably damaging	0.99
R1418:Dnah7a	UTSW	1	53,686,395 (GRCm39)	splice site	probably benign
R1421:Dnah7a	UTSW	1	53,580,032 (GRCm39)	splice site	probably benign
R1445:Dnah7a	UTSW	1	53,567,956 (GRCm39)	missense	probably benign	0.02
R1473:Dnah7a	UTSW	1	53,535,173 (GRCm39)	missense	probably benign	0.00
R1538:Dnah7a	UTSW	1	53,535,148 (GRCm39)	missense	possibly damaging	0.71
R1742:Dnah7a	UTSW	1	53,495,843 (GRCm39)	missense	probably benign	0.39
R1754:Dnah7a	UTSW	1	53,601,059 (GRCm39)	critical splice donor site	probably null
R1754:Dnah7a	UTSW	1	53,543,344 (GRCm39)	missense	probably benign	0.18
R1773:Dnah7a	UTSW	1	53,472,046 (GRCm39)	splice site	probably null
R1779:Dnah7a	UTSW	1	53,616,382 (GRCm39)	missense	probably benign
R1816:Dnah7a	UTSW	1	53,670,901 (GRCm39)	splice site	probably benign
R1817:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1818:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1819:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1873:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1875:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1884:Dnah7a	UTSW	1	53,580,159 (GRCm39)	missense	probably damaging	0.99
R1902:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1903:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1908:Dnah7a	UTSW	1	53,670,721 (GRCm39)	missense	probably benign
R1959:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1960:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1985:Dnah7a	UTSW	1	53,543,093 (GRCm39)	missense	probably benign	0.01
R1992:Dnah7a	UTSW	1	53,621,835 (GRCm39)	missense	possibly damaging	0.91
R2037:Dnah7a	UTSW	1	53,621,741 (GRCm39)	missense	probably benign	0.00
R2074:Dnah7a	UTSW	1	53,496,855 (GRCm39)	missense	probably benign	0.45
R2076:Dnah7a	UTSW	1	53,542,968 (GRCm39)	missense	probably benign	0.01
R2191:Dnah7a	UTSW	1	53,645,034 (GRCm39)	missense	possibly damaging	0.54
R2211:Dnah7a	UTSW	1	53,518,932 (GRCm39)	missense	probably benign	0.21
R2220:Dnah7a	UTSW	1	53,560,333 (GRCm39)	missense	probably benign
R2355:Dnah7a	UTSW	1	53,621,661 (GRCm39)	missense	probably benign	0.00
R2495:Dnah7a	UTSW	1	53,645,040 (GRCm39)	missense	probably damaging	1.00
R2901:Dnah7a	UTSW	1	53,467,031 (GRCm39)	missense	probably damaging	0.99
R2911:Dnah7a	UTSW	1	53,466,983 (GRCm39)	critical splice donor site	probably null
R2993:Dnah7a	UTSW	1	53,542,713 (GRCm39)	missense	probably damaging	1.00
R3522:Dnah7a	UTSW	1	53,657,275 (GRCm39)	missense	probably damaging	1.00
R3683:Dnah7a	UTSW	1	53,483,675 (GRCm39)	missense	probably benign
R3723:Dnah7a	UTSW	1	53,486,505 (GRCm39)	missense	probably benign	0.04
R3847:Dnah7a	UTSW	1	53,540,815 (GRCm39)	missense	probably benign	0.01
R4002:Dnah7a	UTSW	1	53,670,840 (GRCm39)	missense	probably benign
R4009:Dnah7a	UTSW	1	53,564,164 (GRCm39)	missense	probably damaging	1.00
R4063:Dnah7a	UTSW	1	53,464,376 (GRCm39)	missense	probably benign
R4193:Dnah7a	UTSW	1	53,486,493 (GRCm39)	missense	probably benign	0.00
R4236:Dnah7a	UTSW	1	53,486,524 (GRCm39)	missense	probably benign	0.00
R4399:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R4469:Dnah7a	UTSW	1	53,483,685 (GRCm39)	missense	probably benign	0.01
R4494:Dnah7a	UTSW	1	53,488,197 (GRCm39)	missense	probably benign	0.01
R4569:Dnah7a	UTSW	1	53,450,818 (GRCm39)	missense	probably benign	0.01
R4609:Dnah7a	UTSW	1	53,495,816 (GRCm39)	missense	possibly damaging	0.80
R4632:Dnah7a	UTSW	1	53,467,110 (GRCm39)	missense	probably damaging	0.97
R4703:Dnah7a	UTSW	1	53,486,476 (GRCm39)	critical splice donor site	probably null
R4781:Dnah7a	UTSW	1	53,464,367 (GRCm39)	missense	probably benign	0.28
R4854:Dnah7a	UTSW	1	53,745,888 (GRCm39)	utr 5 prime	probably benign
R4932:Dnah7a	UTSW	1	53,542,737 (GRCm39)	missense	possibly damaging	0.90
R4976:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5000:Dnah7a	UTSW	1	53,606,201 (GRCm39)	missense	probably damaging	1.00
R5023:Dnah7a	UTSW	1	53,686,407 (GRCm39)	nonsense	probably null
R5026:Dnah7a	UTSW	1	53,701,657 (GRCm39)	missense	probably damaging	0.99
R5050:Dnah7a	UTSW	1	53,536,255 (GRCm39)	missense	probably benign	0.01
R5119:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5151:Dnah7a	UTSW	1	53,659,929 (GRCm39)	missense	probably benign	0.00
R5155:Dnah7a	UTSW	1	53,682,654 (GRCm39)	missense	probably benign	0.01
R5180:Dnah7a	UTSW	1	53,462,446 (GRCm39)	missense	probably damaging	0.97
R5228:Dnah7a	UTSW	1	53,476,768 (GRCm39)	critical splice acceptor site	probably null
R5237:Dnah7a	UTSW	1	53,486,690 (GRCm39)	splice site	probably null
R5267:Dnah7a	UTSW	1	53,518,851 (GRCm39)	missense	probably damaging	1.00
R5334:Dnah7a	UTSW	1	53,542,805 (GRCm39)	missense	probably benign	0.00
R5358:Dnah7a	UTSW	1	53,586,331 (GRCm39)	missense	probably damaging	1.00
R5401:Dnah7a	UTSW	1	53,670,812 (GRCm39)	missense	probably benign	0.01
R5412:Dnah7a	UTSW	1	53,674,503 (GRCm39)	missense	probably benign
R5496:Dnah7a	UTSW	1	53,496,927 (GRCm39)	missense	probably benign
R5531:Dnah7a	UTSW	1	53,458,907 (GRCm39)	missense	possibly damaging	0.50
R5536:Dnah7a	UTSW	1	53,464,412 (GRCm39)	missense	probably benign
R5543:Dnah7a	UTSW	1	53,543,228 (GRCm39)	missense	probably damaging	1.00
R5597:Dnah7a	UTSW	1	53,573,611 (GRCm39)	missense	probably benign	0.00
R5609:Dnah7a	UTSW	1	53,621,753 (GRCm39)	missense	probably benign	0.03
R5643:Dnah7a	UTSW	1	53,444,866 (GRCm39)	missense	probably benign
R5644:Dnah7a	UTSW	1	53,580,138 (GRCm39)	missense	probably benign	0.33
R5689:Dnah7a	UTSW	1	53,444,857 (GRCm39)	missense	possibly damaging	0.87
R5715:Dnah7a	UTSW	1	53,452,937 (GRCm39)	missense	probably damaging	1.00
R5780:Dnah7a	UTSW	1	53,522,478 (GRCm39)	missense	probably benign	0.03
R5893:Dnah7a	UTSW	1	53,496,944 (GRCm39)	missense	possibly damaging	0.66
R5946:Dnah7a	UTSW	1	53,598,467 (GRCm39)	missense	probably damaging	1.00
R5995:Dnah7a	UTSW	1	53,659,829 (GRCm39)	missense	probably benign	0.00
R6102:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R6108:Dnah7a	UTSW	1	53,496,004 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah7a	UTSW	1	53,458,814 (GRCm39)	missense	probably benign	0.05
R6168:Dnah7a	UTSW	1	53,450,727 (GRCm39)	missense	probably damaging	1.00
R6175:Dnah7a	UTSW	1	53,472,181 (GRCm39)	missense	probably damaging	1.00
R6211:Dnah7a	UTSW	1	53,458,795 (GRCm39)	missense	probably damaging	0.99
R6282:Dnah7a	UTSW	1	53,542,760 (GRCm39)	missense	probably damaging	1.00
R6329:Dnah7a	UTSW	1	53,580,273 (GRCm39)	missense	probably damaging	1.00
R6344:Dnah7a	UTSW	1	53,436,349 (GRCm39)	missense	probably benign	0.02
R6530:Dnah7a	UTSW	1	53,542,856 (GRCm39)	missense	probably benign	0.04
R6574:Dnah7a	UTSW	1	53,495,693 (GRCm39)	critical splice donor site	probably null
R6608:Dnah7a	UTSW	1	53,564,277 (GRCm39)	missense	probably benign
R6625:Dnah7a	UTSW	1	53,604,916 (GRCm39)	missense	probably benign	0.05
R6661:Dnah7a	UTSW	1	53,662,609 (GRCm39)	missense	probably benign	0.00
R6681:Dnah7a	UTSW	1	53,560,385 (GRCm39)	critical splice acceptor site	probably null
R6747:Dnah7a	UTSW	1	53,675,221 (GRCm39)	missense	probably benign	0.01
R6774:Dnah7a	UTSW	1	53,737,810 (GRCm39)	missense	probably benign
R6823:Dnah7a	UTSW	1	53,495,863 (GRCm39)	missense	probably benign
R6900:Dnah7a	UTSW	1	53,701,510 (GRCm39)	missense	probably damaging	0.97
R6940:Dnah7a	UTSW	1	53,670,836 (GRCm39)	missense	probably benign	0.09
R6956:Dnah7a	UTSW	1	53,616,446 (GRCm39)	missense	probably benign	0.02
R6978:Dnah7a	UTSW	1	53,701,526 (GRCm39)	missense	probably null
R6988:Dnah7a	UTSW	1	53,621,784 (GRCm39)	missense	possibly damaging	0.62
R7026:Dnah7a	UTSW	1	53,543,448 (GRCm39)	missense	probably benign
R7027:Dnah7a	UTSW	1	53,670,665 (GRCm39)	missense	probably benign	0.01
R7033:Dnah7a	UTSW	1	53,518,820 (GRCm39)	missense	probably damaging	1.00
R7072:Dnah7a	UTSW	1	53,458,912 (GRCm39)	missense	probably benign	0.00
R7096:Dnah7a	UTSW	1	53,522,599 (GRCm39)	missense	possibly damaging	0.90
R7142:Dnah7a	UTSW	1	53,452,927 (GRCm39)	nonsense	probably null
R7144:Dnah7a	UTSW	1	53,737,867 (GRCm39)	splice site	probably null
R7167:Dnah7a	UTSW	1	53,542,935 (GRCm39)	missense	probably benign	0.00
R7182:Dnah7a	UTSW	1	53,659,620 (GRCm39)	splice site	probably null
R7196:Dnah7a	UTSW	1	53,724,000 (GRCm39)	missense	probably benign	0.00
R7206:Dnah7a	UTSW	1	53,737,792 (GRCm39)	nonsense	probably null
R7215:Dnah7a	UTSW	1	53,657,509 (GRCm39)	missense	probably damaging	0.99
R7224:Dnah7a	UTSW	1	53,436,420 (GRCm39)	missense	probably benign	0.00
R7264:Dnah7a	UTSW	1	53,557,973 (GRCm39)	missense	probably benign
R7282:Dnah7a	UTSW	1	53,724,059 (GRCm39)	critical splice acceptor site	probably null
R7365:Dnah7a	UTSW	1	53,536,297 (GRCm39)	missense	probably benign
R7392:Dnah7a	UTSW	1	53,540,820 (GRCm39)	missense	probably benign	0.00
R7454:Dnah7a	UTSW	1	53,557,923 (GRCm39)	missense	probably benign
R7471:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
R7547:Dnah7a	UTSW	1	53,702,996 (GRCm39)	missense	probably benign	0.00
R7554:Dnah7a	UTSW	1	53,567,857 (GRCm39)	missense	possibly damaging	0.87
R7655:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7656:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7666:Dnah7a	UTSW	1	53,586,456 (GRCm39)	missense	probably benign	0.00
R7721:Dnah7a	UTSW	1	53,670,842 (GRCm39)	missense	probably benign
R7813:Dnah7a	UTSW	1	53,657,245 (GRCm39)	missense	probably benign
R7839:Dnah7a	UTSW	1	53,606,334 (GRCm39)	missense	probably benign	0.08
R7959:Dnah7a	UTSW	1	53,682,621 (GRCm39)	missense	probably benign	0.00
R7984:Dnah7a	UTSW	1	53,543,377 (GRCm39)	missense	probably benign	0.01
R7985:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R8116:Dnah7a	UTSW	1	53,543,049 (GRCm39)	missense	probably benign
R8140:Dnah7a	UTSW	1	53,540,748 (GRCm39)	missense	probably benign	0.02
R8184:Dnah7a	UTSW	1	53,666,194 (GRCm39)	missense	probably benign	0.03
R8339:Dnah7a	UTSW	1	53,724,178 (GRCm39)	missense	probably benign
R8352:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8423:Dnah7a	UTSW	1	53,512,063 (GRCm39)	missense	possibly damaging	0.84
R8428:Dnah7a	UTSW	1	53,512,112 (GRCm39)	missense	probably damaging	0.98
R8432:Dnah7a	UTSW	1	53,657,195 (GRCm39)	missense	possibly damaging	0.46
R8452:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8458:Dnah7a	UTSW	1	53,657,142 (GRCm39)	missense	probably benign	0.01
R8493:Dnah7a	UTSW	1	53,512,067 (GRCm39)	missense	probably damaging	1.00
R8498:Dnah7a	UTSW	1	53,657,139 (GRCm39)	missense	probably benign	0.01
R8502:Dnah7a	UTSW	1	53,679,520 (GRCm39)	missense	probably benign	0.39
R8692:Dnah7a	UTSW	1	53,472,175 (GRCm39)	missense	probably benign	0.00
R8700:Dnah7a	UTSW	1	53,535,088 (GRCm39)	missense	possibly damaging	0.62
R8709:Dnah7a	UTSW	1	53,674,476 (GRCm39)	missense	probably benign
R8856:Dnah7a	UTSW	1	53,462,422 (GRCm39)	missense	probably damaging	1.00
R8875:Dnah7a	UTSW	1	53,682,682 (GRCm39)	missense	probably benign	0.10
R8967:Dnah7a	UTSW	1	53,682,594 (GRCm39)	splice site	probably benign
R8982:Dnah7a	UTSW	1	53,570,301 (GRCm39)	missense	probably benign
R8984:Dnah7a	UTSW	1	53,674,436 (GRCm39)	nonsense	probably null
R8993:Dnah7a	UTSW	1	53,543,262 (GRCm39)	missense	probably damaging	1.00
R9008:Dnah7a	UTSW	1	53,701,501 (GRCm39)	missense	possibly damaging	0.81
R9022:Dnah7a	UTSW	1	53,512,116 (GRCm39)	critical splice acceptor site	probably null
R9028:Dnah7a	UTSW	1	53,560,297 (GRCm39)	missense	probably benign	0.00
R9077:Dnah7a	UTSW	1	53,741,218 (GRCm39)	missense	unknown
R9167:Dnah7a	UTSW	1	53,657,370 (GRCm39)	missense	probably benign	0.00
R9206:Dnah7a	UTSW	1	53,540,757 (GRCm39)	missense	probably benign	0.11
R9226:Dnah7a	UTSW	1	53,560,326 (GRCm39)	missense	possibly damaging	0.93
R9251:Dnah7a	UTSW	1	53,621,671 (GRCm39)	missense	probably damaging	1.00
R9265:Dnah7a	UTSW	1	53,674,505 (GRCm39)	missense	probably benign
R9350:Dnah7a	UTSW	1	53,436,307 (GRCm39)	missense	probably benign	0.19
R9369:Dnah7a	UTSW	1	53,564,222 (GRCm39)	missense	possibly damaging	0.72
R9369:Dnah7a	UTSW	1	53,543,421 (GRCm39)	missense	probably benign
R9372:Dnah7a	UTSW	1	53,543,474 (GRCm39)	missense	probably benign
R9376:Dnah7a	UTSW	1	53,568,058 (GRCm39)	critical splice acceptor site	probably null
R9378:Dnah7a	UTSW	1	53,621,776 (GRCm39)	missense	probably benign	0.32
R9401:Dnah7a	UTSW	1	53,568,026 (GRCm39)	missense	probably benign	0.01
R9431:Dnah7a	UTSW	1	53,450,812 (GRCm39)	missense	possibly damaging	0.90
R9529:Dnah7a	UTSW	1	53,561,495 (GRCm39)	missense	probably damaging	1.00
R9701:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
R9712:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R9799:Dnah7a	UTSW	1	53,557,968 (GRCm39)	missense	probably benign	0.00
R9802:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
X0027:Dnah7a	UTSW	1	53,512,089 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah7a	UTSW	1	53,507,802 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,522,622 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah7a	UTSW	1	53,598,261 (GRCm39)	missense	probably benign	0.21
Z1177:Dnah7a	UTSW	1	53,450,815 (GRCm39)	missense	probably benign	0.08
Z1177:Dnah7a	UTSW	1	53,682,616 (GRCm39)	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- GTAAACTAGGGAATCCTCTTGCC -3'
(R):5'- TTTGGATAAGCTGGACTCGGC -3'

Sequencing Primer
(F):5'- TTGAGAGAAACTAAACTGTGGTCCCC -3'
(R):5'- GCATCATCCCAGGTGGCAAC -3'

Posted On

2014-09-17