Mutagenetix > Incidental Mutation

Incidental Mutation 'R2124:Dnah7a'

229627

Institutional Source

Beutler Lab

Gene Symbol

Dnah7a

Ensembl Gene

ENSMUSG00000096141

Gene Name

dynein, axonemal, heavy chain 7A

Synonyms

Dnahc7a, Dnahc7, LOC381341

MMRRC Submission

040127-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.104) question?

Stock #

R2124 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

53397006-53706784 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 53496942 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 2647 (D2647E)

Ref Sequence

ENSEMBL: ENSMUSP00000092571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094964]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000094964
AA Change: D2647E

PolyPhen 2 Score 0.583 (Sensitivity: 0.88; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000092571
Gene: ENSMUSG00000096141
AA Change: D2647E

Domain	Start	End	E-Value	Type
low complexity region	2	15	N/A	INTRINSIC
coiled coil region	504	537	N/A	INTRINSIC
Pfam:DHC_N2	756	1165	3.1e-149	PFAM
AAA	1320	1459	2.46e-1	SMART
Blast:AAA	1601	1879	1e-87	BLAST
AAA	1968	2116	5.39e-2	SMART
Pfam:AAA_8	2303	2574	6.9e-75	PFAM
Pfam:MT	2586	2936	2.1e-55	PFAM
Pfam:AAA_9	2957	3182	1.3e-98	PFAM
Pfam:Dynein_heavy	3318	4020	2.3e-287	PFAM

Meta Mutation Damage Score

0.0821

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.2%

Validation Efficiency

98% (80/82)

Allele List at MGI

Other mutations in this stock

Total: 78 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933430I17Rik	T	A	4: 62,538,872 (GRCm38)	L143M	possibly damaging	Het
Abca13	T	C	11: 9,309,013 (GRCm38)		probably benign	Het
Abcg5	T	A	17: 84,671,147 (GRCm38)	E294D	probably benign	Het
Adgrg6	T	C	10: 14,467,186 (GRCm38)	D339G	probably damaging	Het
Ahctf1	C	A	1: 179,769,452 (GRCm38)	R43L	probably damaging	Het
Ambn	T	A	5: 88,460,758 (GRCm38)		probably benign	Het
Arap3	A	C	18: 37,973,350 (GRCm38)	L1480R	probably damaging	Het
Arhgef10	A	G	8: 14,934,820 (GRCm38)	D200G	probably damaging	Het
Aspg	G	A	12: 112,121,174 (GRCm38)	V8I	probably benign	Het
Aven	T	A	2: 112,625,196 (GRCm38)	W26R	probably damaging	Het
Car4	T	A	11: 84,964,085 (GRCm38)		probably benign	Het
Cd163	C	T	6: 124,318,856 (GRCm38)	R720C	probably damaging	Het
Cdh1	A	G	8: 106,664,210 (GRCm38)	I653V	probably benign	Het
Cdh3	A	T	8: 106,552,888 (GRCm38)	H712L	probably damaging	Het
Cdr2	T	C	7: 120,982,027 (GRCm38)	E9G	probably damaging	Het
Chrnb2	T	C	3: 89,769,341 (GRCm38)		probably benign	Het
Col4a2	C	A	8: 11,416,070 (GRCm38)	P443Q	probably damaging	Het
Cyp2a12	A	G	7: 27,036,646 (GRCm38)	*493W	probably null	Het
Ddias	T	C	7: 92,858,256 (GRCm38)	Q817R	probably benign	Het
Ddx6	C	T	9: 44,624,519 (GRCm38)	Q182*	probably null	Het
Dhrs7	A	G	12: 72,653,177 (GRCm38)	I227T	probably damaging	Het
Dhx8	A	T	11: 101,762,245 (GRCm38)	M970L	probably damaging	Het
Dstyk	G	A	1: 132,453,119 (GRCm38)	G451R	possibly damaging	Het
Ednrb	T	A	14: 103,821,768 (GRCm38)	D274V	probably benign	Het
Efl1	C	T	7: 82,692,913 (GRCm38)	R510C	probably damaging	Het
Eif4g3	A	G	4: 138,184,742 (GRCm38)	E1409G	probably damaging	Het
Fam78b	G	A	1: 167,078,709 (GRCm38)	V146M	probably damaging	Het
Fcgbp	T	C	7: 28,092,019 (GRCm38)	Y902H	probably benign	Het
Fgf18	A	C	11: 33,118,003 (GRCm38)	F129C	probably damaging	Het
Gbp9	T	A	5: 105,094,543 (GRCm38)	D110V	probably damaging	Het
Gm10477	A	G	X: 56,524,832 (GRCm38)	K31E	probably damaging	Het
Gm10542	T	A	18: 44,201,288 (GRCm38)	W9R	probably null	Het
Gm7173	T	C	X: 79,510,321 (GRCm38)	I267V	probably benign	Het
Gpaa1	A	G	15: 76,333,352 (GRCm38)	Y330C	probably damaging	Het
Hectd4	T	C	5: 121,318,639 (GRCm38)	L689P	probably damaging	Het
Hoxd3	C	A	2: 74,744,234 (GRCm38)	P75T	possibly damaging	Het
Ikbkb	T	C	8: 22,667,217 (GRCm38)		probably benign	Het
Ikbkb	A	G	8: 22,666,020 (GRCm38)	L570P	probably damaging	Het
Il1rap	A	T	16: 26,710,565 (GRCm38)	H379L	probably damaging	Het
Ints6l	T	A	X: 56,504,868 (GRCm38)	S718T	probably benign	Het
Jaml	T	A	9: 45,101,064 (GRCm38)	I283N	probably damaging	Het
Kidins220	G	A	12: 25,041,303 (GRCm38)		probably null	Het
Kif1b	T	C	4: 149,222,296 (GRCm38)	D869G	probably benign	Het
Loxl2	T	C	14: 69,692,410 (GRCm38)	Y746H	probably benign	Het
Ltbr	A	G	6: 125,309,477 (GRCm38)	S249P	probably benign	Het
Mageb5	A	G	X: 91,780,095 (GRCm38)	I226T	probably damaging	Het
Msantd2	C	T	9: 37,522,931 (GRCm38)	R357W	probably damaging	Het
Neb	A	G	2: 52,264,064 (GRCm38)	F2345S	probably damaging	Het
Olfr866	T	G	9: 20,027,501 (GRCm38)	I146L	probably benign	Het
Pabpc4l	T	C	3: 46,446,841 (GRCm38)	T123A	probably benign	Het
Plekhg4	TAGTCGATGCCCGAGTC	TAGTC	8: 105,376,452 (GRCm38)		probably benign	Het
Prkdc	T	C	16: 15,719,433 (GRCm38)	V1716A	probably benign	Het
Prss37	G	A	6: 40,515,360 (GRCm38)	R186*	probably null	Het
Psg20	T	A	7: 18,681,022 (GRCm38)	Y316F	probably benign	Het
Rasgrp2	T	A	19: 6,404,395 (GRCm38)	M156K	probably benign	Het
Rims1	T	A	1: 22,404,508 (GRCm38)	R200*	probably null	Het
Rnf168	T	G	16: 32,278,218 (GRCm38)	L37R	probably damaging	Het
Sall3	C	T	18: 80,971,797 (GRCm38)	G972D	probably benign	Het
Sap18	T	A	14: 57,798,554 (GRCm38)	S66T	probably damaging	Het
Scamp5	C	A	9: 57,447,225 (GRCm38)	V49F	possibly damaging	Het
Sdk1	C	A	5: 142,185,188 (GRCm38)	D1935E	possibly damaging	Het
Setd2	A	G	9: 110,549,864 (GRCm38)	S632G	probably benign	Het
Soga1	T	C	2: 157,033,325 (GRCm38)	E835G	probably damaging	Het
Syt16	T	A	12: 74,238,235 (GRCm38)	S401T	probably damaging	Het
Tas2r106	A	T	6: 131,678,354 (GRCm38)	L178H	probably damaging	Het
Tbcd	A	G	11: 121,603,320 (GRCm38)	Y983C	probably damaging	Het
Tenm3	A	G	8: 48,417,006 (GRCm38)		probably null	Het
Tll1	T	C	8: 64,085,557 (GRCm38)	E351G	probably benign	Het
Tmem44	T	A	16: 30,547,444 (GRCm38)	K55*	probably null	Het
Top2a	T	C	11: 99,004,228 (GRCm38)	I849V	probably benign	Het
Ttn	A	G	2: 76,794,448 (GRCm38)	V13516A	probably damaging	Het
Uxs1	A	G	1: 43,774,846 (GRCm38)	L77P	probably damaging	Het
Vmn2r121	A	T	X: 124,133,742 (GRCm38)		probably null	Het
Vmn2r84	A	C	10: 130,391,231 (GRCm38)	M246R	probably damaging	Het
Vps13b	T	A	15: 35,646,080 (GRCm38)	N1443K	probably benign	Het
Wfdc6b	C	T	2: 164,617,443 (GRCm38)	R142C	probably benign	Het
Zfp616	A	G	11: 74,083,043 (GRCm38)		probably null	Het
Zmym1	T	C	4: 127,049,570 (GRCm38)	T244A	probably benign	Het

Other mutations in Dnah7a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00479:Dnah7a	APN	1	53,419,684 (GRCm38)	missense	probably damaging	0.99
IGL00510:Dnah7a	APN	1	53,501,542 (GRCm38)	missense	probably damaging	1.00
IGL00545:Dnah7a	APN	1	53,457,746 (GRCm38)	missense	possibly damaging	0.87
IGL01320:Dnah7a	APN	1	53,434,046 (GRCm38)	missense	probably benign	0.32
IGL01322:Dnah7a	APN	1	53,434,046 (GRCm38)	missense	probably benign	0.32
IGL01357:Dnah7a	APN	1	53,662,381 (GRCm38)	missense	probably benign
IGL01417:Dnah7a	APN	1	53,584,600 (GRCm38)	missense	probably benign	0.01
IGL01508:Dnah7a	APN	1	53,627,072 (GRCm38)	missense	probably benign	0.00
IGL01511:Dnah7a	APN	1	53,419,595 (GRCm38)	missense	probably damaging	1.00
IGL01545:Dnah7a	APN	1	53,518,782 (GRCm38)	missense	probably benign
IGL01575:Dnah7a	APN	1	53,427,820 (GRCm38)	splice site	probably benign
IGL01667:Dnah7a	APN	1	53,547,292 (GRCm38)	missense	probably damaging	1.00
IGL01712:Dnah7a	APN	1	53,423,270 (GRCm38)	missense	probably benign	0.23
IGL01824:Dnah7a	APN	1	53,504,270 (GRCm38)	missense	probably benign
IGL01829:Dnah7a	APN	1	53,618,068 (GRCm38)	missense	possibly damaging	0.64
IGL01861:Dnah7a	APN	1	53,584,449 (GRCm38)	splice site	probably benign
IGL01861:Dnah7a	APN	1	53,640,349 (GRCm38)	missense	probably benign	0.01
IGL01984:Dnah7a	APN	1	53,702,015 (GRCm38)	splice site	probably null
IGL02056:Dnah7a	APN	1	53,504,342 (GRCm38)	missense	probably benign	0.17
IGL02069:Dnah7a	APN	1	53,561,894 (GRCm38)	splice site	probably benign
IGL02072:Dnah7a	APN	1	53,605,827 (GRCm38)	missense	probably damaging	1.00
IGL02110:Dnah7a	APN	1	53,411,580 (GRCm38)	missense	possibly damaging	0.52
IGL02120:Dnah7a	APN	1	53,495,717 (GRCm38)	missense	possibly damaging	0.46
IGL02128:Dnah7a	APN	1	53,437,513 (GRCm38)	missense	probably damaging	1.00
IGL02135:Dnah7a	APN	1	53,623,473 (GRCm38)	missense	probably benign	0.01
IGL02151:Dnah7a	APN	1	53,472,864 (GRCm38)	missense	probably benign	0.08
IGL02156:Dnah7a	APN	1	53,419,723 (GRCm38)	missense	probably benign	0.27
IGL02270:Dnah7a	APN	1	53,472,893 (GRCm38)	missense	possibly damaging	0.93
IGL02282:Dnah7a	APN	1	53,643,510 (GRCm38)	missense	possibly damaging	0.93
IGL02328:Dnah7a	APN	1	53,524,937 (GRCm38)	critical splice donor site	probably null
IGL02370:Dnah7a	APN	1	53,635,397 (GRCm38)	missense	probably benign	0.00
IGL02420:Dnah7a	APN	1	53,686,543 (GRCm38)	missense	probably benign
IGL02458:Dnah7a	APN	1	53,618,328 (GRCm38)	nonsense	probably null
IGL02489:Dnah7a	APN	1	53,647,322 (GRCm38)	missense	possibly damaging	0.94
IGL02554:Dnah7a	APN	1	53,618,046 (GRCm38)	missense	possibly damaging	0.93
IGL02578:Dnah7a	APN	1	53,432,915 (GRCm38)	missense	probably benign	0.00
IGL02646:Dnah7a	APN	1	53,525,035 (GRCm38)	missense	probably damaging	0.99
IGL02675:Dnah7a	APN	1	53,504,024 (GRCm38)	missense	possibly damaging	0.96
IGL02688:Dnah7a	APN	1	53,444,472 (GRCm38)	missense	possibly damaging	0.93
IGL02858:Dnah7a	APN	1	53,472,959 (GRCm38)	splice site	probably benign
IGL02874:Dnah7a	APN	1	53,605,814 (GRCm38)	missense	possibly damaging	0.70
IGL02887:Dnah7a	APN	1	53,522,360 (GRCm38)	missense	possibly damaging	0.46
IGL02894:Dnah7a	APN	1	53,577,328 (GRCm38)	missense	probably benign	0.27
IGL02926:Dnah7a	APN	1	53,495,950 (GRCm38)	missense	possibly damaging	0.64
IGL03113:Dnah7a	APN	1	53,433,004 (GRCm38)	missense	possibly damaging	0.64
IGL03156:Dnah7a	APN	1	53,605,824 (GRCm38)	missense	probably damaging	0.97
IGL03195:Dnah7a	APN	1	53,419,607 (GRCm38)	missense	probably damaging	1.00
IGL03209:Dnah7a	APN	1	53,686,614 (GRCm38)	splice site	probably benign
IGL03214:Dnah7a	APN	1	53,522,209 (GRCm38)	critical splice donor site	probably null
IGL03242:Dnah7a	APN	1	53,620,723 (GRCm38)	missense	probably benign	0.02
IGL03251:Dnah7a	APN	1	53,647,274 (GRCm38)	missense	probably benign
IGL03265:Dnah7a	APN	1	53,528,848 (GRCm38)	missense	probably benign
IGL03277:Dnah7a	APN	1	53,630,322 (GRCm38)	missense	probably benign	0.00
IGL03278:Dnah7a	APN	1	53,496,965 (GRCm38)	missense	probably benign	0.07
IGL03356:Dnah7a	APN	1	53,503,934 (GRCm38)	missense	probably benign	0.01
PIT4378001:Dnah7a	UTSW	1	53,531,203 (GRCm38)	missense	probably damaging	0.99
R0046:Dnah7a	UTSW	1	53,456,874 (GRCm38)	splice site	probably null
R0051:Dnah7a	UTSW	1	53,521,086 (GRCm38)	splice site	probably benign
R0082:Dnah7a	UTSW	1	53,518,708 (GRCm38)	missense	probably damaging	1.00
R0111:Dnah7a	UTSW	1	53,468,684 (GRCm38)	missense	probably benign	0.03
R0122:Dnah7a	UTSW	1	53,397,142 (GRCm38)	missense	probably damaging	1.00
R0245:Dnah7a	UTSW	1	53,501,526 (GRCm38)	missense	probably damaging	1.00
R0278:Dnah7a	UTSW	1	53,504,146 (GRCm38)	missense	probably benign	0.00
R0309:Dnah7a	UTSW	1	53,405,690 (GRCm38)	missense	probably damaging	0.97
R0334:Dnah7a	UTSW	1	53,433,054 (GRCm38)	missense	possibly damaging	0.61
R0392:Dnah7a	UTSW	1	53,504,198 (GRCm38)	missense	probably damaging	0.97
R0452:Dnah7a	UTSW	1	53,605,819 (GRCm38)	missense	probably benign	0.00
R0511:Dnah7a	UTSW	1	53,497,126 (GRCm38)	missense	probably benign
R0576:Dnah7a	UTSW	1	53,636,087 (GRCm38)	missense	probably benign	0.12
R0592:Dnah7a	UTSW	1	53,456,612 (GRCm38)	missense	possibly damaging	0.91
R0628:Dnah7a	UTSW	1	53,497,105 (GRCm38)	missense	probably benign	0.18
R0689:Dnah7a	UTSW	1	53,620,681 (GRCm38)	nonsense	probably null
R0735:Dnah7a	UTSW	1	53,544,511 (GRCm38)	missense	possibly damaging	0.70
R0800:Dnah7a	UTSW	1	53,565,696 (GRCm38)	missense	probably damaging	1.00
R0829:Dnah7a	UTSW	1	53,504,079 (GRCm38)	missense	probably benign	0.07
R0842:Dnah7a	UTSW	1	53,501,674 (GRCm38)	missense	possibly damaging	0.88
R0879:Dnah7a	UTSW	1	53,427,860 (GRCm38)	missense	possibly damaging	0.85
R1331:Dnah7a	UTSW	1	53,468,669 (GRCm38)	missense	probably damaging	0.99
R1418:Dnah7a	UTSW	1	53,647,236 (GRCm38)	splice site	probably benign
R1421:Dnah7a	UTSW	1	53,540,873 (GRCm38)	splice site	probably benign
R1445:Dnah7a	UTSW	1	53,528,797 (GRCm38)	missense	probably benign	0.02
R1473:Dnah7a	UTSW	1	53,496,014 (GRCm38)	missense	probably benign	0.00
R1538:Dnah7a	UTSW	1	53,495,989 (GRCm38)	missense	possibly damaging	0.71
R1742:Dnah7a	UTSW	1	53,456,684 (GRCm38)	missense	probably benign	0.39
R1754:Dnah7a	UTSW	1	53,561,900 (GRCm38)	critical splice donor site	probably null
R1754:Dnah7a	UTSW	1	53,504,185 (GRCm38)	missense	probably benign	0.18
R1773:Dnah7a	UTSW	1	53,432,887 (GRCm38)	splice site	probably null
R1779:Dnah7a	UTSW	1	53,577,223 (GRCm38)	missense	probably benign
R1816:Dnah7a	UTSW	1	53,631,742 (GRCm38)	splice site	probably benign
R1817:Dnah7a	UTSW	1	53,559,148 (GRCm38)	missense	probably benign
R1818:Dnah7a	UTSW	1	53,559,148 (GRCm38)	missense	probably benign
R1819:Dnah7a	UTSW	1	53,559,148 (GRCm38)	missense	probably benign
R1873:Dnah7a	UTSW	1	53,456,532 (GRCm38)	splice site	probably benign
R1875:Dnah7a	UTSW	1	53,456,532 (GRCm38)	splice site	probably benign
R1884:Dnah7a	UTSW	1	53,541,000 (GRCm38)	missense	probably damaging	0.99
R1902:Dnah7a	UTSW	1	53,535,478 (GRCm38)	missense	probably damaging	1.00
R1903:Dnah7a	UTSW	1	53,535,478 (GRCm38)	missense	probably damaging	1.00
R1908:Dnah7a	UTSW	1	53,631,562 (GRCm38)	missense	probably benign
R1959:Dnah7a	UTSW	1	53,684,983 (GRCm38)	missense	probably benign	0.00
R1960:Dnah7a	UTSW	1	53,684,983 (GRCm38)	missense	probably benign	0.00
R1985:Dnah7a	UTSW	1	53,503,934 (GRCm38)	missense	probably benign	0.01
R1992:Dnah7a	UTSW	1	53,582,676 (GRCm38)	missense	possibly damaging	0.91
R2037:Dnah7a	UTSW	1	53,582,582 (GRCm38)	missense	probably benign	0.00
R2074:Dnah7a	UTSW	1	53,457,696 (GRCm38)	missense	probably benign	0.45
R2076:Dnah7a	UTSW	1	53,503,809 (GRCm38)	missense	probably benign	0.01
R2191:Dnah7a	UTSW	1	53,605,875 (GRCm38)	missense	possibly damaging	0.54
R2211:Dnah7a	UTSW	1	53,479,773 (GRCm38)	missense	probably benign	0.21
R2220:Dnah7a	UTSW	1	53,521,174 (GRCm38)	missense	probably benign
R2355:Dnah7a	UTSW	1	53,582,502 (GRCm38)	missense	probably benign	0.00
R2495:Dnah7a	UTSW	1	53,605,881 (GRCm38)	missense	probably damaging	1.00
R2901:Dnah7a	UTSW	1	53,427,872 (GRCm38)	missense	probably damaging	0.99
R2911:Dnah7a	UTSW	1	53,427,824 (GRCm38)	critical splice donor site	probably null
R2993:Dnah7a	UTSW	1	53,503,554 (GRCm38)	missense	probably damaging	1.00
R3522:Dnah7a	UTSW	1	53,618,116 (GRCm38)	missense	probably damaging	1.00
R3683:Dnah7a	UTSW	1	53,444,516 (GRCm38)	missense	probably benign
R3723:Dnah7a	UTSW	1	53,447,346 (GRCm38)	missense	probably benign	0.04
R3847:Dnah7a	UTSW	1	53,501,656 (GRCm38)	missense	probably benign	0.01
R4002:Dnah7a	UTSW	1	53,631,681 (GRCm38)	missense	probably benign
R4009:Dnah7a	UTSW	1	53,525,005 (GRCm38)	missense	probably damaging	1.00
R4063:Dnah7a	UTSW	1	53,425,217 (GRCm38)	missense	probably benign
R4193:Dnah7a	UTSW	1	53,447,334 (GRCm38)	missense	probably benign	0.00
R4236:Dnah7a	UTSW	1	53,447,365 (GRCm38)	missense	probably benign	0.00
R4399:Dnah7a	UTSW	1	53,518,727 (GRCm38)	missense	probably damaging	1.00
R4469:Dnah7a	UTSW	1	53,444,526 (GRCm38)	missense	probably benign	0.01
R4494:Dnah7a	UTSW	1	53,449,038 (GRCm38)	missense	probably benign	0.01
R4569:Dnah7a	UTSW	1	53,411,659 (GRCm38)	missense	probably benign	0.01
R4609:Dnah7a	UTSW	1	53,456,657 (GRCm38)	missense	possibly damaging	0.80
R4632:Dnah7a	UTSW	1	53,427,951 (GRCm38)	missense	probably damaging	0.97
R4703:Dnah7a	UTSW	1	53,447,317 (GRCm38)	critical splice donor site	probably null
R4781:Dnah7a	UTSW	1	53,425,208 (GRCm38)	missense	probably benign	0.28
R4854:Dnah7a	UTSW	1	53,706,729 (GRCm38)	utr 5 prime	probably benign
R4932:Dnah7a	UTSW	1	53,503,578 (GRCm38)	missense	possibly damaging	0.90
R4976:Dnah7a	UTSW	1	53,698,692 (GRCm38)	missense	probably benign
R5000:Dnah7a	UTSW	1	53,567,042 (GRCm38)	missense	probably damaging	1.00
R5023:Dnah7a	UTSW	1	53,647,248 (GRCm38)	nonsense	probably null
R5026:Dnah7a	UTSW	1	53,662,498 (GRCm38)	missense	probably damaging	0.99
R5050:Dnah7a	UTSW	1	53,497,096 (GRCm38)	missense	probably benign	0.01
R5119:Dnah7a	UTSW	1	53,698,692 (GRCm38)	missense	probably benign
R5151:Dnah7a	UTSW	1	53,620,770 (GRCm38)	missense	probably benign	0.00
R5155:Dnah7a	UTSW	1	53,643,495 (GRCm38)	missense	probably benign	0.01
R5180:Dnah7a	UTSW	1	53,423,287 (GRCm38)	missense	probably damaging	0.97
R5228:Dnah7a	UTSW	1	53,437,609 (GRCm38)	critical splice acceptor site	probably null
R5237:Dnah7a	UTSW	1	53,447,531 (GRCm38)	splice site	probably null
R5267:Dnah7a	UTSW	1	53,479,692 (GRCm38)	missense	probably damaging	1.00
R5334:Dnah7a	UTSW	1	53,503,646 (GRCm38)	missense	probably benign	0.00
R5358:Dnah7a	UTSW	1	53,547,172 (GRCm38)	missense	probably damaging	1.00
R5401:Dnah7a	UTSW	1	53,631,653 (GRCm38)	missense	probably benign	0.01
R5412:Dnah7a	UTSW	1	53,635,344 (GRCm38)	missense	probably benign
R5496:Dnah7a	UTSW	1	53,457,768 (GRCm38)	missense	probably benign
R5531:Dnah7a	UTSW	1	53,419,748 (GRCm38)	missense	possibly damaging	0.50
R5536:Dnah7a	UTSW	1	53,425,253 (GRCm38)	missense	probably benign
R5543:Dnah7a	UTSW	1	53,504,069 (GRCm38)	missense	probably damaging	1.00
R5597:Dnah7a	UTSW	1	53,534,452 (GRCm38)	missense	probably benign	0.00
R5609:Dnah7a	UTSW	1	53,582,594 (GRCm38)	missense	probably benign	0.03
R5643:Dnah7a	UTSW	1	53,405,707 (GRCm38)	missense	probably benign
R5644:Dnah7a	UTSW	1	53,540,979 (GRCm38)	missense	probably benign	0.33
R5689:Dnah7a	UTSW	1	53,405,698 (GRCm38)	missense	possibly damaging	0.87
R5715:Dnah7a	UTSW	1	53,413,778 (GRCm38)	missense	probably damaging	1.00
R5780:Dnah7a	UTSW	1	53,483,319 (GRCm38)	missense	probably benign	0.03
R5893:Dnah7a	UTSW	1	53,457,785 (GRCm38)	missense	possibly damaging	0.66
R5946:Dnah7a	UTSW	1	53,559,308 (GRCm38)	missense	probably damaging	1.00
R5995:Dnah7a	UTSW	1	53,620,670 (GRCm38)	missense	probably benign	0.00
R6102:Dnah7a	UTSW	1	53,559,140 (GRCm38)	missense	probably benign	0.00
R6108:Dnah7a	UTSW	1	53,456,845 (GRCm38)	missense	probably damaging	1.00
R6133:Dnah7a	UTSW	1	53,419,655 (GRCm38)	missense	probably benign	0.05
R6168:Dnah7a	UTSW	1	53,411,568 (GRCm38)	missense	probably damaging	1.00
R6175:Dnah7a	UTSW	1	53,433,022 (GRCm38)	missense	probably damaging	1.00
R6211:Dnah7a	UTSW	1	53,419,636 (GRCm38)	missense	probably damaging	0.99
R6282:Dnah7a	UTSW	1	53,503,601 (GRCm38)	missense	probably damaging	1.00
R6329:Dnah7a	UTSW	1	53,541,114 (GRCm38)	missense	probably damaging	1.00
R6344:Dnah7a	UTSW	1	53,397,190 (GRCm38)	missense	probably benign	0.02
R6530:Dnah7a	UTSW	1	53,503,697 (GRCm38)	missense	probably benign	0.04
R6574:Dnah7a	UTSW	1	53,456,534 (GRCm38)	critical splice donor site	probably null
R6608:Dnah7a	UTSW	1	53,525,118 (GRCm38)	missense	probably benign
R6625:Dnah7a	UTSW	1	53,565,757 (GRCm38)	missense	probably benign	0.05
R6661:Dnah7a	UTSW	1	53,623,450 (GRCm38)	missense	probably benign	0.00
R6681:Dnah7a	UTSW	1	53,521,226 (GRCm38)	critical splice acceptor site	probably null
R6747:Dnah7a	UTSW	1	53,636,062 (GRCm38)	missense	probably benign	0.01
R6774:Dnah7a	UTSW	1	53,698,651 (GRCm38)	missense	probably benign
R6823:Dnah7a	UTSW	1	53,456,704 (GRCm38)	missense	probably benign
R6900:Dnah7a	UTSW	1	53,662,351 (GRCm38)	missense	probably damaging	0.97
R6940:Dnah7a	UTSW	1	53,631,677 (GRCm38)	missense	probably benign	0.09
R6956:Dnah7a	UTSW	1	53,577,287 (GRCm38)	missense	probably benign	0.02
R6978:Dnah7a	UTSW	1	53,662,367 (GRCm38)	missense	probably null
R6988:Dnah7a	UTSW	1	53,582,625 (GRCm38)	missense	possibly damaging	0.62
R7026:Dnah7a	UTSW	1	53,504,289 (GRCm38)	missense	probably benign
R7027:Dnah7a	UTSW	1	53,631,506 (GRCm38)	missense	probably benign	0.01
R7033:Dnah7a	UTSW	1	53,479,661 (GRCm38)	missense	probably damaging	1.00
R7072:Dnah7a	UTSW	1	53,419,753 (GRCm38)	missense	probably benign	0.00
R7096:Dnah7a	UTSW	1	53,483,440 (GRCm38)	missense	possibly damaging	0.90
R7142:Dnah7a	UTSW	1	53,413,768 (GRCm38)	nonsense	probably null
R7144:Dnah7a	UTSW	1	53,698,708 (GRCm38)	splice site	probably null
R7167:Dnah7a	UTSW	1	53,503,776 (GRCm38)	missense	probably benign	0.00
R7182:Dnah7a	UTSW	1	53,620,461 (GRCm38)	splice site	probably null
R7196:Dnah7a	UTSW	1	53,684,841 (GRCm38)	missense	probably benign	0.00
R7206:Dnah7a	UTSW	1	53,698,633 (GRCm38)	nonsense	probably null
R7215:Dnah7a	UTSW	1	53,618,350 (GRCm38)	missense	probably damaging	0.99
R7224:Dnah7a	UTSW	1	53,397,261 (GRCm38)	missense	probably benign	0.00
R7264:Dnah7a	UTSW	1	53,518,814 (GRCm38)	missense	probably benign
R7282:Dnah7a	UTSW	1	53,684,900 (GRCm38)	critical splice acceptor site	probably null
R7365:Dnah7a	UTSW	1	53,497,138 (GRCm38)	missense	probably benign
R7392:Dnah7a	UTSW	1	53,501,661 (GRCm38)	missense	probably benign	0.00
R7454:Dnah7a	UTSW	1	53,518,764 (GRCm38)	missense	probably benign
R7471:Dnah7a	UTSW	1	53,419,699 (GRCm38)	missense	probably damaging	1.00
R7547:Dnah7a	UTSW	1	53,663,837 (GRCm38)	missense	probably benign	0.00
R7554:Dnah7a	UTSW	1	53,528,698 (GRCm38)	missense	possibly damaging	0.87
R7655:Dnah7a	UTSW	1	53,496,005 (GRCm38)	missense	possibly damaging	0.50
R7656:Dnah7a	UTSW	1	53,496,005 (GRCm38)	missense	possibly damaging	0.50
R7666:Dnah7a	UTSW	1	53,547,297 (GRCm38)	missense	probably benign	0.00
R7721:Dnah7a	UTSW	1	53,631,683 (GRCm38)	missense	probably benign
R7813:Dnah7a	UTSW	1	53,618,086 (GRCm38)	missense	probably benign
R7839:Dnah7a	UTSW	1	53,567,175 (GRCm38)	missense	probably benign	0.08
R7959:Dnah7a	UTSW	1	53,643,462 (GRCm38)	missense	probably benign	0.00
R7984:Dnah7a	UTSW	1	53,504,218 (GRCm38)	missense	probably benign	0.01
R7985:Dnah7a	UTSW	1	53,518,727 (GRCm38)	missense	probably damaging	1.00
R8116:Dnah7a	UTSW	1	53,503,890 (GRCm38)	missense	probably benign
R8140:Dnah7a	UTSW	1	53,501,589 (GRCm38)	missense	probably benign	0.02
R8184:Dnah7a	UTSW	1	53,627,035 (GRCm38)	missense	probably benign	0.03
R8339:Dnah7a	UTSW	1	53,685,019 (GRCm38)	missense	probably benign
R8352:Dnah7a	UTSW	1	53,427,827 (GRCm38)	missense	probably null	0.01
R8423:Dnah7a	UTSW	1	53,472,904 (GRCm38)	missense	possibly damaging	0.84
R8428:Dnah7a	UTSW	1	53,472,953 (GRCm38)	missense	probably damaging	0.98
R8432:Dnah7a	UTSW	1	53,618,036 (GRCm38)	missense	possibly damaging	0.46
R8452:Dnah7a	UTSW	1	53,427,827 (GRCm38)	missense	probably null	0.01
R8458:Dnah7a	UTSW	1	53,617,983 (GRCm38)	missense	probably benign	0.01
R8493:Dnah7a	UTSW	1	53,472,908 (GRCm38)	missense	probably damaging	1.00
R8498:Dnah7a	UTSW	1	53,617,980 (GRCm38)	missense	probably benign	0.01
R8502:Dnah7a	UTSW	1	53,640,361 (GRCm38)	missense	probably benign	0.39
R8692:Dnah7a	UTSW	1	53,433,016 (GRCm38)	missense	probably benign	0.00
R8700:Dnah7a	UTSW	1	53,495,929 (GRCm38)	missense	possibly damaging	0.62
R8709:Dnah7a	UTSW	1	53,635,317 (GRCm38)	missense	probably benign
R8856:Dnah7a	UTSW	1	53,423,263 (GRCm38)	missense	probably damaging	1.00
R8875:Dnah7a	UTSW	1	53,643,523 (GRCm38)	missense	probably benign	0.10
R8967:Dnah7a	UTSW	1	53,643,435 (GRCm38)	splice site	probably benign
R8982:Dnah7a	UTSW	1	53,531,142 (GRCm38)	missense	probably benign
R8984:Dnah7a	UTSW	1	53,635,277 (GRCm38)	nonsense	probably null
R8993:Dnah7a	UTSW	1	53,504,103 (GRCm38)	missense	probably damaging	1.00
R9008:Dnah7a	UTSW	1	53,662,342 (GRCm38)	missense	possibly damaging	0.81
R9022:Dnah7a	UTSW	1	53,472,957 (GRCm38)	critical splice acceptor site	probably null
R9028:Dnah7a	UTSW	1	53,521,138 (GRCm38)	missense	probably benign	0.00
R9077:Dnah7a	UTSW	1	53,702,059 (GRCm38)	missense	unknown
R9167:Dnah7a	UTSW	1	53,618,211 (GRCm38)	missense	probably benign	0.00
R9206:Dnah7a	UTSW	1	53,501,598 (GRCm38)	missense	probably benign	0.11
R9226:Dnah7a	UTSW	1	53,521,167 (GRCm38)	missense	possibly damaging	0.93
R9251:Dnah7a	UTSW	1	53,582,512 (GRCm38)	missense	probably damaging	1.00
R9265:Dnah7a	UTSW	1	53,635,346 (GRCm38)	missense	probably benign
R9350:Dnah7a	UTSW	1	53,397,148 (GRCm38)	missense	probably benign	0.19
R9369:Dnah7a	UTSW	1	53,525,063 (GRCm38)	missense	possibly damaging	0.72
R9369:Dnah7a	UTSW	1	53,504,262 (GRCm38)	missense	probably benign
R9372:Dnah7a	UTSW	1	53,504,315 (GRCm38)	missense	probably benign
R9376:Dnah7a	UTSW	1	53,528,899 (GRCm38)	critical splice acceptor site	probably null
R9378:Dnah7a	UTSW	1	53,582,617 (GRCm38)	missense	probably benign	0.32
R9401:Dnah7a	UTSW	1	53,528,867 (GRCm38)	missense	probably benign	0.01
R9431:Dnah7a	UTSW	1	53,411,653 (GRCm38)	missense	possibly damaging	0.90
R9529:Dnah7a	UTSW	1	53,522,336 (GRCm38)	missense	probably damaging	1.00
R9701:Dnah7a	UTSW	1	53,522,229 (GRCm38)	missense	probably benign	0.03
R9712:Dnah7a	UTSW	1	53,559,140 (GRCm38)	missense	probably benign	0.00
R9799:Dnah7a	UTSW	1	53,518,809 (GRCm38)	missense	probably benign	0.00
R9802:Dnah7a	UTSW	1	53,522,229 (GRCm38)	missense	probably benign	0.03
X0027:Dnah7a	UTSW	1	53,472,930 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah7a	UTSW	1	53,468,643 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,483,463 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,419,699 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah7a	UTSW	1	53,559,102 (GRCm38)	missense	probably benign	0.21
Z1177:Dnah7a	UTSW	1	53,411,656 (GRCm38)	missense	probably benign	0.08
Z1177:Dnah7a	UTSW	1	53,643,457 (GRCm38)	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- GTAAACTAGGGAATCCTCTTGCC -3'
(R):5'- TTTGGATAAGCTGGACTCGGC -3'

Sequencing Primer
(F):5'- TTGAGAGAAACTAAACTGTGGTCCCC -3'
(R):5'- GCATCATCCCAGGTGGCAAC -3'

Posted On

2014-09-17