Incidental Mutation 'R2125:Mybpc1'
| ID |
229781 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mybpc1
|
| Ensembl Gene |
ENSMUSG00000020061 |
| Gene Name |
myosin binding protein C, slow-type |
| Synonyms |
Slow-type C-protein, 8030451F13Rik |
| MMRRC Submission |
040128-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.837)
|
| Stock # |
R2125 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
88354141-88441014 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 88409299 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Stop codon
at position 66
(Q66*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112615
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000119185]
[ENSMUST00000121629]
|
| AlphaFold |
A0A571BEN1 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000119185
AA Change: Q52*
|
| SMART Domains |
Protein: ENSMUSP00000112699
Gene: ENSMUSG00000020061
AA Change: Q52*
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
51 |
147 |
1.96e-6 |
SMART |
|
low complexity region
|
221 |
233 |
N/A |
INTRINSIC |
|
IG
|
246 |
325 |
4.53e-2 |
SMART |
|
IG
|
335 |
416 |
1.13e-2 |
SMART |
|
IG
|
426 |
506 |
6.97e-3 |
SMART |
|
IG
|
519 |
604 |
2.83e-3 |
SMART |
|
FN3
|
607 |
690 |
4.28e-10 |
SMART |
|
FN3
|
705 |
788 |
1.49e-9 |
SMART |
|
low complexity region
|
800 |
812 |
N/A |
INTRINSIC |
|
IG
|
815 |
898 |
9.06e-2 |
SMART |
|
FN3
|
901 |
983 |
2.06e-12 |
SMART |
|
IGc2
|
1028 |
1095 |
1.88e-8 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000121629
AA Change: Q66*
|
| SMART Domains |
Protein: ENSMUSP00000112615
Gene: ENSMUSG00000020061
AA Change: Q66*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
27 |
N/A |
INTRINSIC |
|
IG
|
65 |
161 |
1.96e-6 |
SMART |
|
low complexity region
|
235 |
247 |
N/A |
INTRINSIC |
|
IG
|
260 |
339 |
4.53e-2 |
SMART |
|
IG
|
349 |
430 |
1.13e-2 |
SMART |
|
IG
|
440 |
520 |
6.97e-3 |
SMART |
|
IG
|
533 |
618 |
2.83e-3 |
SMART |
|
FN3
|
621 |
704 |
4.28e-10 |
SMART |
|
FN3
|
719 |
802 |
1.49e-9 |
SMART |
|
low complexity region
|
814 |
826 |
N/A |
INTRINSIC |
|
IG
|
829 |
912 |
9.06e-2 |
SMART |
|
FN3
|
915 |
997 |
2.06e-12 |
SMART |
|
IGc2
|
1042 |
1109 |
1.88e-8 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadac |
A |
G |
3: 59,947,066 (GRCm39) |
T255A |
possibly damaging |
Het |
| Abcb10 |
A |
C |
8: 124,691,831 (GRCm39) |
V378G |
probably benign |
Het |
| Ackr2 |
C |
T |
9: 121,737,852 (GRCm39) |
R76* |
probably null |
Het |
| Acly |
T |
C |
11: 100,414,322 (GRCm39) |
T35A |
probably benign |
Het |
| Acp7 |
A |
C |
7: 28,328,974 (GRCm39) |
F69V |
probably damaging |
Het |
| Acsl3 |
T |
A |
1: 78,659,678 (GRCm39) |
I110N |
probably damaging |
Het |
| Adam5 |
C |
T |
8: 25,305,134 (GRCm39) |
V107M |
probably damaging |
Het |
| Adck2 |
T |
C |
6: 39,552,076 (GRCm39) |
V281A |
probably benign |
Het |
| Adgrv1 |
A |
G |
13: 81,567,654 (GRCm39) |
V5173A |
probably benign |
Het |
| Adgrv1 |
A |
T |
13: 81,568,069 (GRCm39) |
S5035T |
probably benign |
Het |
| Arl10 |
T |
A |
13: 54,726,937 (GRCm39) |
|
probably null |
Het |
| B3gnt3 |
A |
G |
8: 72,146,002 (GRCm39) |
W176R |
probably damaging |
Het |
| B4galt4 |
T |
C |
16: 38,586,300 (GRCm39) |
I3T |
probably damaging |
Het |
| Casr |
T |
C |
16: 36,315,614 (GRCm39) |
I819V |
possibly damaging |
Het |
| Cdh1 |
T |
C |
8: 107,383,472 (GRCm39) |
V237A |
probably damaging |
Het |
| Col22a1 |
G |
A |
15: 71,720,426 (GRCm39) |
R605C |
unknown |
Het |
| Crlf3 |
A |
G |
11: 79,950,081 (GRCm39) |
V183A |
probably benign |
Het |
| Crtac1 |
C |
A |
19: 42,312,171 (GRCm39) |
V181L |
probably damaging |
Het |
| Dclk2 |
C |
T |
3: 86,712,946 (GRCm39) |
R503Q |
possibly damaging |
Het |
| Dnah12 |
A |
T |
14: 26,445,613 (GRCm39) |
R725* |
probably null |
Het |
| Dnhd1 |
A |
T |
7: 105,327,178 (GRCm39) |
H709L |
probably benign |
Het |
| Dop1a |
A |
G |
9: 86,403,099 (GRCm39) |
Y1431C |
probably damaging |
Het |
| Ecpas |
T |
C |
4: 58,833,978 (GRCm39) |
H834R |
probably benign |
Het |
| Eif2ak4 |
A |
T |
2: 118,252,604 (GRCm39) |
H392L |
probably benign |
Het |
| Entpd3 |
T |
C |
9: 120,384,720 (GRCm39) |
I99T |
probably damaging |
Het |
| Epha6 |
T |
C |
16: 59,503,051 (GRCm39) |
D952G |
probably damaging |
Het |
| Exoc6 |
T |
C |
19: 37,579,389 (GRCm39) |
L429P |
probably damaging |
Het |
| F13a1 |
A |
G |
13: 37,076,815 (GRCm39) |
S625P |
probably benign |
Het |
| Fcgbpl1 |
A |
T |
7: 27,857,447 (GRCm39) |
Y2265F |
probably benign |
Het |
| Fcho2 |
T |
C |
13: 98,912,406 (GRCm39) |
N240S |
possibly damaging |
Het |
| Fcrl6 |
C |
T |
1: 172,426,815 (GRCm39) |
V44M |
probably benign |
Het |
| Fmo6 |
A |
T |
1: 162,757,527 (GRCm39) |
M82K |
possibly damaging |
Het |
| Gabrr2 |
T |
G |
4: 33,095,548 (GRCm39) |
I479R |
probably damaging |
Het |
| Gnl2 |
T |
A |
4: 124,947,278 (GRCm39) |
F633L |
probably benign |
Het |
| Greb1l |
C |
T |
18: 10,511,422 (GRCm39) |
S648F |
probably damaging |
Het |
| Gsap |
T |
A |
5: 21,447,811 (GRCm39) |
C290S |
probably damaging |
Het |
| Gusb |
A |
G |
5: 130,028,288 (GRCm39) |
V268A |
probably benign |
Het |
| H2-D1 |
G |
A |
17: 35,483,091 (GRCm39) |
|
probably null |
Het |
| Hebp2 |
T |
A |
10: 18,417,008 (GRCm39) |
E164D |
probably benign |
Het |
| Higd1a |
A |
T |
9: 121,679,313 (GRCm39) |
I58N |
probably damaging |
Het |
| Hoxc13 |
G |
T |
15: 102,835,658 (GRCm39) |
R262L |
probably damaging |
Het |
| Ifih1 |
A |
G |
2: 62,453,811 (GRCm39) |
V218A |
probably benign |
Het |
| Impg2 |
T |
A |
16: 56,085,427 (GRCm39) |
Y1045N |
probably damaging |
Het |
| Kcnk1 |
A |
G |
8: 126,722,395 (GRCm39) |
E66G |
probably damaging |
Het |
| Klkb1 |
A |
G |
8: 45,728,541 (GRCm39) |
V406A |
possibly damaging |
Het |
| Klra10 |
G |
A |
6: 130,256,241 (GRCm39) |
R138W |
probably damaging |
Het |
| Lama2 |
A |
C |
10: 26,920,449 (GRCm39) |
Y193* |
probably null |
Het |
| Larp7 |
T |
C |
3: 127,336,779 (GRCm39) |
T428A |
probably benign |
Het |
| Lipg |
T |
C |
18: 75,078,956 (GRCm39) |
N432S |
probably benign |
Het |
| Loxl1 |
T |
C |
9: 58,200,995 (GRCm39) |
D489G |
probably damaging |
Het |
| Lrguk |
A |
G |
6: 34,069,837 (GRCm39) |
K571E |
probably benign |
Het |
| Map3k13 |
C |
T |
16: 21,710,894 (GRCm39) |
T59I |
probably benign |
Het |
| Mertk |
T |
A |
2: 128,604,058 (GRCm39) |
D397E |
probably benign |
Het |
| Mgat3 |
G |
A |
15: 80,096,087 (GRCm39) |
V305I |
probably benign |
Het |
| Mrtfb |
T |
C |
16: 13,218,668 (GRCm39) |
V449A |
possibly damaging |
Het |
| Myo3a |
A |
G |
2: 22,468,186 (GRCm39) |
D480G |
probably benign |
Het |
| Ndufaf3 |
C |
T |
9: 108,443,936 (GRCm39) |
R31Q |
probably benign |
Het |
| Neb |
T |
C |
2: 52,200,650 (GRCm39) |
Y343C |
probably damaging |
Het |
| Nrxn3 |
A |
G |
12: 89,227,290 (GRCm39) |
|
probably null |
Het |
| Or4c10b |
A |
G |
2: 89,711,982 (GRCm39) |
M271V |
probably benign |
Het |
| Or8k40 |
A |
T |
2: 86,584,796 (GRCm39) |
N95K |
probably benign |
Het |
| Pcsk4 |
T |
C |
10: 80,159,713 (GRCm39) |
M379V |
probably benign |
Het |
| Pdzd2 |
A |
T |
15: 12,373,676 (GRCm39) |
V2153E |
probably benign |
Het |
| Pkd2l1 |
T |
C |
19: 44,142,939 (GRCm39) |
D427G |
possibly damaging |
Het |
| Plcd4 |
A |
G |
1: 74,604,311 (GRCm39) |
Y763C |
probably damaging |
Het |
| Plekhh1 |
T |
C |
12: 79,125,774 (GRCm39) |
F1270S |
probably damaging |
Het |
| Pmfbp1 |
T |
C |
8: 110,246,905 (GRCm39) |
V259A |
probably damaging |
Het |
| Ptprg |
T |
C |
14: 12,179,283 (GRCm38) |
S767P |
possibly damaging |
Het |
| Rabl3 |
T |
G |
16: 37,377,175 (GRCm39) |
|
probably null |
Het |
| Rffl |
T |
A |
11: 82,709,264 (GRCm39) |
H53L |
probably damaging |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Rtl1 |
C |
T |
12: 109,560,355 (GRCm39) |
V495I |
possibly damaging |
Het |
| Scaf11 |
A |
T |
15: 96,317,196 (GRCm39) |
D789E |
possibly damaging |
Het |
| Scn2a |
T |
A |
2: 65,582,423 (GRCm39) |
Y1590* |
probably null |
Het |
| Siglech |
T |
A |
7: 55,421,434 (GRCm39) |
F190I |
probably benign |
Het |
| Slc22a22 |
C |
A |
15: 57,117,636 (GRCm39) |
A302S |
probably damaging |
Het |
| Slc46a3 |
T |
A |
5: 147,815,954 (GRCm39) |
T458S |
probably benign |
Het |
| Spta1 |
G |
T |
1: 174,035,910 (GRCm39) |
R1072L |
possibly damaging |
Het |
| Tbx5 |
A |
G |
5: 119,974,988 (GRCm39) |
T4A |
probably benign |
Het |
| Tdrd5 |
T |
C |
1: 156,104,143 (GRCm39) |
R528G |
probably damaging |
Het |
| Tfip11 |
T |
C |
5: 112,483,529 (GRCm39) |
V648A |
possibly damaging |
Het |
| Thumpd3 |
T |
C |
6: 113,043,749 (GRCm39) |
V388A |
probably benign |
Het |
| Tmem131l |
C |
T |
3: 83,850,058 (GRCm39) |
|
probably null |
Het |
| Ttf2 |
C |
A |
3: 100,855,509 (GRCm39) |
Q895H |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,720,436 (GRCm39) |
|
probably null |
Het |
| Vmn2r13 |
A |
G |
5: 109,306,058 (GRCm39) |
S507P |
probably benign |
Het |
| Vtn |
A |
G |
11: 78,391,049 (GRCm39) |
T210A |
probably damaging |
Het |
| Zfp1010 |
C |
A |
2: 176,957,195 (GRCm39) |
C101F |
probably damaging |
Het |
| Znhit2 |
A |
G |
19: 6,112,091 (GRCm39) |
T279A |
probably benign |
Het |
|
| Other mutations in Mybpc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00468:Mybpc1
|
APN |
10 |
88,385,124 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00577:Mybpc1
|
APN |
10 |
88,372,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00703:Mybpc1
|
APN |
10 |
88,360,970 (GRCm39) |
splice site |
probably null |
|
|
IGL00964:Mybpc1
|
APN |
10 |
88,391,604 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01738:Mybpc1
|
APN |
10 |
88,406,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01978:Mybpc1
|
APN |
10 |
88,367,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02255:Mybpc1
|
APN |
10 |
88,372,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02997:Mybpc1
|
APN |
10 |
88,362,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0098:Mybpc1
|
UTSW |
10 |
88,365,426 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0240:Mybpc1
|
UTSW |
10 |
88,391,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0240:Mybpc1
|
UTSW |
10 |
88,391,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0449:Mybpc1
|
UTSW |
10 |
88,376,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0879:Mybpc1
|
UTSW |
10 |
88,407,378 (GRCm39) |
splice site |
probably benign |
|
|
R1321:Mybpc1
|
UTSW |
10 |
88,406,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1321:Mybpc1
|
UTSW |
10 |
88,365,403 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1562:Mybpc1
|
UTSW |
10 |
88,389,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1783:Mybpc1
|
UTSW |
10 |
88,406,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1803:Mybpc1
|
UTSW |
10 |
88,389,157 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1962:Mybpc1
|
UTSW |
10 |
88,384,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Mybpc1
|
UTSW |
10 |
88,387,404 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2006:Mybpc1
|
UTSW |
10 |
88,381,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2129:Mybpc1
|
UTSW |
10 |
88,387,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2163:Mybpc1
|
UTSW |
10 |
88,376,804 (GRCm39) |
splice site |
probably benign |
|
|
R2200:Mybpc1
|
UTSW |
10 |
88,391,557 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2219:Mybpc1
|
UTSW |
10 |
88,391,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2270:Mybpc1
|
UTSW |
10 |
88,387,269 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2961:Mybpc1
|
UTSW |
10 |
88,367,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3767:Mybpc1
|
UTSW |
10 |
88,406,521 (GRCm39) |
splice site |
probably null |
|
|
R4032:Mybpc1
|
UTSW |
10 |
88,365,426 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4226:Mybpc1
|
UTSW |
10 |
88,409,387 (GRCm39) |
nonsense |
probably null |
|
|
R4821:Mybpc1
|
UTSW |
10 |
88,384,727 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4876:Mybpc1
|
UTSW |
10 |
88,372,286 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4876:Mybpc1
|
UTSW |
10 |
88,358,853 (GRCm39) |
missense |
probably benign |
|
|
R4878:Mybpc1
|
UTSW |
10 |
88,387,292 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4910:Mybpc1
|
UTSW |
10 |
88,391,586 (GRCm39) |
nonsense |
probably null |
|
|
R4913:Mybpc1
|
UTSW |
10 |
88,389,116 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4964:Mybpc1
|
UTSW |
10 |
88,391,525 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5023:Mybpc1
|
UTSW |
10 |
88,379,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5098:Mybpc1
|
UTSW |
10 |
88,381,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5196:Mybpc1
|
UTSW |
10 |
88,372,213 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5344:Mybpc1
|
UTSW |
10 |
88,406,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5399:Mybpc1
|
UTSW |
10 |
88,358,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5538:Mybpc1
|
UTSW |
10 |
88,381,891 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5808:Mybpc1
|
UTSW |
10 |
88,406,428 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5970:Mybpc1
|
UTSW |
10 |
88,378,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6324:Mybpc1
|
UTSW |
10 |
88,404,481 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6433:Mybpc1
|
UTSW |
10 |
88,396,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6441:Mybpc1
|
UTSW |
10 |
88,389,139 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6648:Mybpc1
|
UTSW |
10 |
88,358,861 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6844:Mybpc1
|
UTSW |
10 |
88,372,243 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6931:Mybpc1
|
UTSW |
10 |
88,378,192 (GRCm39) |
nonsense |
probably null |
|
|
R6972:Mybpc1
|
UTSW |
10 |
88,396,223 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6973:Mybpc1
|
UTSW |
10 |
88,396,223 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6978:Mybpc1
|
UTSW |
10 |
88,358,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7007:Mybpc1
|
UTSW |
10 |
88,389,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7019:Mybpc1
|
UTSW |
10 |
88,379,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7407:Mybpc1
|
UTSW |
10 |
88,385,209 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7442:Mybpc1
|
UTSW |
10 |
88,362,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7577:Mybpc1
|
UTSW |
10 |
88,385,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7660:Mybpc1
|
UTSW |
10 |
88,384,716 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7768:Mybpc1
|
UTSW |
10 |
88,378,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mybpc1
|
UTSW |
10 |
88,394,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Mybpc1
|
UTSW |
10 |
88,358,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8195:Mybpc1
|
UTSW |
10 |
88,394,553 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R8241:Mybpc1
|
UTSW |
10 |
88,372,286 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8360:Mybpc1
|
UTSW |
10 |
88,409,359 (GRCm39) |
nonsense |
probably null |
|
|
R8494:Mybpc1
|
UTSW |
10 |
88,362,291 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8849:Mybpc1
|
UTSW |
10 |
88,407,447 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8936:Mybpc1
|
UTSW |
10 |
88,394,437 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9031:Mybpc1
|
UTSW |
10 |
88,358,906 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9061:Mybpc1
|
UTSW |
10 |
88,391,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9081:Mybpc1
|
UTSW |
10 |
88,389,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9172:Mybpc1
|
UTSW |
10 |
88,379,615 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9323:Mybpc1
|
UTSW |
10 |
88,360,829 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9460:Mybpc1
|
UTSW |
10 |
88,372,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9488:Mybpc1
|
UTSW |
10 |
88,379,624 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9757:Mybpc1
|
UTSW |
10 |
88,372,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9796:Mybpc1
|
UTSW |
10 |
88,406,497 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
Z1176:Mybpc1
|
UTSW |
10 |
88,396,189 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Mybpc1
|
UTSW |
10 |
88,409,299 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGGATGCTAGATCTCCTGG -3'
(R):5'- AATGAGAATCTGTCCCTCTCCAC -3'
Sequencing Primer
(F):5'- CTAGATCTCCTGGGGGTGC -3'
(R):5'- GGACAAGGGAATGCTGTCATTTTATC -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation