|Institutional Source||Beutler Lab|
|Gene Name||hyaluronoglucosaminidase 4|
|Essential gene?||Non essential (E-score: 0.000)|
|Stock #||R2085 (G1)|
|Chromosomal Location||24748329-24767662 bp(+) (GRCm38)|
|Type of Mutation||start gained|
|DNA Base Change (assembly)||C to T at 24755750 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000031691 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000031691]|
|Coding Region Coverage||
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. [provided by RefSeq, Jul 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Hyal4||
(F):5'- TTGCTTATCCCCGAGTAGAAACC -3'
(R):5'- ATCAAACACAGGTCTGTTGGAG -3'
(F):5'- GAGTAGAAACCTGATCATGACACTTG -3'
(R):5'- CAAACACAGGTCTGTTGGAGCATTC -3'