Incidental Mutation 'R2103:Tns2'
| ID |
230734 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tns2
|
| Ensembl Gene |
ENSMUSG00000037003 |
| Gene Name |
tensin 2 |
| Synonyms |
nep, Tenc1, nph |
| MMRRC Submission |
040107-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2103 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
102008848-102024836 bp(+) (GRCm39) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
A to T
at 102021100 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000155309
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046144]
[ENSMUST00000046144]
[ENSMUST00000154032]
[ENSMUST00000169627]
[ENSMUST00000169627]
[ENSMUST00000228958]
[ENSMUST00000228958]
[ENSMUST00000230474]
[ENSMUST00000230474]
|
| AlphaFold |
Q8CGB6 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000046144
|
| SMART Domains |
Protein: ENSMUSP00000041087
Gene: ENSMUSG00000037003
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
32 |
79 |
2.78e-9 |
SMART |
|
SCOP:d1d5ra2
|
128 |
295 |
8e-24 |
SMART |
|
PTEN_C2
|
297 |
424 |
6.63e-40 |
SMART |
|
low complexity region
|
494 |
513 |
N/A |
INTRINSIC |
|
SH2
|
1136 |
1236 |
1.69e-16 |
SMART |
|
PTB
|
1269 |
1407 |
6.66e-28 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000046144
|
| SMART Domains |
Protein: ENSMUSP00000041087
Gene: ENSMUSG00000037003
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
32 |
79 |
2.78e-9 |
SMART |
|
SCOP:d1d5ra2
|
128 |
295 |
8e-24 |
SMART |
|
PTEN_C2
|
297 |
424 |
6.63e-40 |
SMART |
|
low complexity region
|
494 |
513 |
N/A |
INTRINSIC |
|
SH2
|
1136 |
1236 |
1.69e-16 |
SMART |
|
PTB
|
1269 |
1407 |
6.66e-28 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139279
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154032
|
| SMART Domains |
Protein: ENSMUSP00000121493
Gene: ENSMUSG00000036966
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
28 |
38 |
N/A |
INTRINSIC |
|
SPRY
|
76 |
201 |
1.66e-11 |
SMART |
|
SPRY
|
256 |
441 |
3.28e-15 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000169627
|
| SMART Domains |
Protein: ENSMUSP00000129146
Gene: ENSMUSG00000037003
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
32 |
79 |
2.78e-9 |
SMART |
|
SCOP:d1d5ra2
|
128 |
295 |
8e-24 |
SMART |
|
PTEN_C2
|
297 |
424 |
6.63e-40 |
SMART |
|
low complexity region
|
494 |
513 |
N/A |
INTRINSIC |
|
SH2
|
1129 |
1229 |
1.69e-16 |
SMART |
|
PTB
|
1262 |
1400 |
6.66e-28 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000169627
|
| SMART Domains |
Protein: ENSMUSP00000129146
Gene: ENSMUSG00000037003
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
32 |
79 |
2.78e-9 |
SMART |
|
SCOP:d1d5ra2
|
128 |
295 |
8e-24 |
SMART |
|
PTEN_C2
|
297 |
424 |
6.63e-40 |
SMART |
|
low complexity region
|
494 |
513 |
N/A |
INTRINSIC |
|
SH2
|
1129 |
1229 |
1.69e-16 |
SMART |
|
PTB
|
1262 |
1400 |
6.66e-28 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000228958
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000228958
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000229035
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000229097
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000229800
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000230474
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000230474
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.2%
- 20x: 94.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
PHENOTYPE: Affected mice homozygous for a spontaneous deletion show reduced female fertility, increased blood urea nitrogen, low hematocrit, proteinuria, hypoproteinemia, hypercholesterolemia, small kidneys with a yellowish granular surface, glomerular lesions and premature death; some develop systemic edema. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadac |
C |
A |
3: 59,947,235 (GRCm39) |
P311Q |
probably damaging |
Het |
| Acoxl |
T |
A |
2: 127,814,526 (GRCm39) |
M314K |
probably damaging |
Het |
| Agmat |
A |
T |
4: 141,483,214 (GRCm39) |
D216V |
probably damaging |
Het |
| Aida |
A |
T |
1: 183,094,627 (GRCm39) |
E107D |
probably benign |
Het |
| Ano5 |
A |
G |
7: 51,187,561 (GRCm39) |
K50R |
possibly damaging |
Het |
| Anxa2 |
A |
T |
9: 69,391,098 (GRCm39) |
D95V |
probably damaging |
Het |
| Aspm |
G |
A |
1: 139,419,403 (GRCm39) |
V3023M |
probably damaging |
Het |
| Atg16l2 |
A |
G |
7: 100,939,568 (GRCm39) |
|
probably null |
Het |
| B3galt4 |
G |
A |
17: 34,169,813 (GRCm39) |
R142C |
probably damaging |
Het |
| B3galt5 |
A |
T |
16: 96,117,225 (GRCm39) |
K286M |
probably damaging |
Het |
| Best3 |
A |
C |
10: 116,838,499 (GRCm39) |
I186L |
probably benign |
Het |
| Blm |
G |
T |
7: 80,155,697 (GRCm39) |
|
probably null |
Het |
| Cat |
A |
T |
2: 103,293,660 (GRCm39) |
D389E |
probably damaging |
Het |
| Cert1 |
T |
A |
13: 96,771,394 (GRCm39) |
N550K |
probably damaging |
Het |
| Cluh |
C |
A |
11: 74,550,355 (GRCm39) |
C222* |
probably null |
Het |
| Cntnap2 |
G |
A |
6: 47,275,522 (GRCm39) |
E1325K |
probably damaging |
Het |
| Col14a1 |
A |
T |
15: 55,313,336 (GRCm39) |
D1320V |
unknown |
Het |
| Cpne7 |
A |
G |
8: 123,854,176 (GRCm39) |
K288E |
possibly damaging |
Het |
| Cyp26b1 |
A |
G |
6: 84,552,032 (GRCm39) |
S369P |
possibly damaging |
Het |
| Cyp2j9 |
T |
A |
4: 96,460,201 (GRCm39) |
K434M |
probably damaging |
Het |
| Dpyd |
G |
C |
3: 118,858,601 (GRCm39) |
S605T |
probably benign |
Het |
| Dst |
A |
G |
1: 34,229,339 (GRCm39) |
T1986A |
probably benign |
Het |
| Ebf2 |
T |
A |
14: 67,625,391 (GRCm39) |
V233D |
probably damaging |
Het |
| Ecm2 |
A |
G |
13: 49,683,732 (GRCm39) |
D570G |
probably benign |
Het |
| Efhc1 |
T |
A |
1: 21,059,784 (GRCm39) |
C611* |
probably null |
Het |
| Epop |
T |
C |
11: 97,519,480 (GRCm39) |
T210A |
probably benign |
Het |
| Fdxacb1 |
A |
T |
9: 50,682,946 (GRCm39) |
N101I |
probably benign |
Het |
| Fezf1 |
A |
G |
6: 23,247,331 (GRCm39) |
F248S |
possibly damaging |
Het |
| Galnt16 |
A |
G |
12: 80,630,430 (GRCm39) |
D262G |
probably damaging |
Het |
| Gm9507 |
T |
A |
10: 77,647,500 (GRCm39) |
|
probably benign |
Het |
| Grin2b |
A |
T |
6: 135,757,138 (GRCm39) |
I441N |
probably benign |
Het |
| H2-Eb2 |
A |
G |
17: 34,553,278 (GRCm39) |
I155V |
probably benign |
Het |
| Hectd4 |
C |
A |
5: 121,493,692 (GRCm39) |
D3811E |
probably benign |
Het |
| Herc4 |
T |
C |
10: 63,081,889 (GRCm39) |
S71P |
probably benign |
Het |
| Hhipl1 |
A |
G |
12: 108,293,977 (GRCm39) |
T628A |
probably benign |
Het |
| Hoga1 |
A |
C |
19: 42,048,459 (GRCm39) |
|
probably null |
Het |
| Igf2bp1 |
A |
G |
11: 95,866,122 (GRCm39) |
V122A |
probably damaging |
Het |
| Il10ra |
C |
A |
9: 45,167,109 (GRCm39) |
A481S |
probably benign |
Het |
| Klk1b26 |
A |
T |
7: 43,666,324 (GRCm39) |
T256S |
probably damaging |
Het |
| Kndc1 |
C |
T |
7: 139,501,150 (GRCm39) |
T813I |
probably benign |
Het |
| Limch1 |
A |
G |
5: 67,156,072 (GRCm39) |
K394R |
probably benign |
Het |
| Lrrc37a |
T |
C |
11: 103,391,087 (GRCm39) |
E1446G |
probably benign |
Het |
| Lrrc47 |
C |
T |
4: 154,100,350 (GRCm39) |
R287W |
probably damaging |
Het |
| Mdn1 |
T |
A |
4: 32,738,712 (GRCm39) |
L3555Q |
possibly damaging |
Het |
| Mei1 |
A |
G |
15: 81,987,405 (GRCm39) |
H399R |
possibly damaging |
Het |
| Mei1 |
G |
T |
15: 81,991,237 (GRCm39) |
V472F |
probably damaging |
Het |
| Mrps34 |
T |
A |
17: 25,114,464 (GRCm39) |
|
probably null |
Het |
| Myom3 |
A |
G |
4: 135,503,723 (GRCm39) |
T391A |
probably benign |
Het |
| Nfib |
G |
A |
4: 82,248,645 (GRCm39) |
T314I |
possibly damaging |
Het |
| Or5b99 |
T |
C |
19: 12,976,866 (GRCm39) |
V172A |
possibly damaging |
Het |
| Or5p73 |
A |
G |
7: 108,064,810 (GRCm39) |
N93S |
probably benign |
Het |
| Or6c5 |
T |
C |
10: 129,074,368 (GRCm39) |
S117P |
probably damaging |
Het |
| Or9a2 |
A |
G |
6: 41,748,939 (GRCm39) |
I98T |
probably benign |
Het |
| Pdia3 |
G |
C |
2: 121,264,474 (GRCm39) |
G346A |
probably damaging |
Het |
| Plce1 |
T |
C |
19: 38,766,368 (GRCm39) |
F2117S |
probably damaging |
Het |
| Plec |
A |
G |
15: 76,057,743 (GRCm39) |
F4055L |
probably damaging |
Het |
| Ppip5k1 |
A |
T |
2: 121,152,134 (GRCm39) |
|
probably null |
Het |
| Psma6 |
T |
C |
12: 55,454,842 (GRCm39) |
I57T |
probably benign |
Het |
| Psme2 |
A |
T |
14: 55,828,297 (GRCm39) |
|
probably null |
Het |
| Reln |
A |
T |
5: 22,174,358 (GRCm39) |
D1948E |
possibly damaging |
Het |
| Rsf1 |
GGCG |
GGCGACGGCAGCG |
7: 97,229,113 (GRCm39) |
|
probably benign |
Het |
| Sbno1 |
G |
T |
5: 124,532,000 (GRCm39) |
S727R |
probably damaging |
Het |
| Serpina3m |
C |
A |
12: 104,355,958 (GRCm39) |
Y208* |
probably null |
Het |
| Serpind1 |
T |
C |
16: 17,160,808 (GRCm39) |
V446A |
probably benign |
Het |
| Shc3 |
T |
A |
13: 51,596,872 (GRCm39) |
M384L |
probably benign |
Het |
| Slc38a11 |
A |
G |
2: 65,160,683 (GRCm39) |
F304L |
probably benign |
Het |
| Slc4a5 |
A |
C |
6: 83,201,663 (GRCm39) |
D4A |
probably benign |
Het |
| Slc4a5 |
G |
A |
6: 83,274,360 (GRCm39) |
A1076T |
probably benign |
Het |
| Slpi |
C |
T |
2: 164,197,463 (GRCm39) |
C28Y |
probably damaging |
Het |
| Sptan1 |
T |
C |
2: 29,920,483 (GRCm39) |
S2320P |
probably damaging |
Het |
| Stim2 |
A |
G |
5: 54,262,591 (GRCm39) |
T278A |
possibly damaging |
Het |
| Sympk |
T |
A |
7: 18,788,041 (GRCm39) |
S1186T |
probably benign |
Het |
| Tbrg1 |
T |
C |
9: 37,560,715 (GRCm39) |
D387G |
probably benign |
Het |
| Tnxb |
A |
G |
17: 34,901,225 (GRCm39) |
Y1013C |
probably damaging |
Het |
| Tpsg1 |
T |
C |
17: 25,592,267 (GRCm39) |
S41P |
possibly damaging |
Het |
| Trim36 |
T |
C |
18: 46,329,149 (GRCm39) |
N85S |
probably benign |
Het |
| Trpm6 |
A |
T |
19: 18,773,648 (GRCm39) |
H380L |
probably benign |
Het |
| Tssk4 |
A |
G |
14: 55,888,997 (GRCm39) |
I174M |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,776,735 (GRCm39) |
|
probably null |
Het |
| Vmn2r114 |
ATTT |
ATT |
17: 23,509,906 (GRCm39) |
|
probably null |
Het |
| Vmn2r4 |
T |
A |
3: 64,322,704 (GRCm39) |
N5I |
possibly damaging |
Het |
| Vps11 |
G |
A |
9: 44,270,524 (GRCm39) |
H183Y |
probably damaging |
Het |
| Vsig10l |
A |
G |
7: 43,116,892 (GRCm39) |
T476A |
possibly damaging |
Het |
| Vwa8 |
C |
T |
14: 79,145,670 (GRCm39) |
R116C |
probably damaging |
Het |
| Vwf |
G |
A |
6: 125,623,293 (GRCm39) |
V1797I |
probably benign |
Het |
| Wasl |
A |
T |
6: 24,618,377 (GRCm39) |
S447T |
unknown |
Het |
| Whamm |
C |
T |
7: 81,241,519 (GRCm39) |
R277* |
probably null |
Het |
| Zfp874a |
T |
A |
13: 67,590,623 (GRCm39) |
I354F |
probably benign |
Het |
|
| Other mutations in Tns2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01575:Tns2
|
APN |
15 |
102,021,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01935:Tns2
|
APN |
15 |
102,020,069 (GRCm39) |
splice site |
probably null |
|
|
IGL01994:Tns2
|
APN |
15 |
102,019,814 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02025:Tns2
|
APN |
15 |
102,020,484 (GRCm39) |
nonsense |
probably null |
|
|
IGL02135:Tns2
|
APN |
15 |
102,021,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02355:Tns2
|
APN |
15 |
102,020,725 (GRCm39) |
missense |
probably benign |
|
|
IGL02362:Tns2
|
APN |
15 |
102,020,725 (GRCm39) |
missense |
probably benign |
|
|
IGL02439:Tns2
|
APN |
15 |
102,022,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02488:Tns2
|
APN |
15 |
102,021,178 (GRCm39) |
missense |
probably benign |
|
|
IGL02546:Tns2
|
APN |
15 |
102,019,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02616:Tns2
|
APN |
15 |
102,019,850 (GRCm39) |
missense |
probably benign |
|
|
IGL02628:Tns2
|
APN |
15 |
102,020,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02658:Tns2
|
APN |
15 |
102,016,231 (GRCm39) |
splice site |
probably benign |
|
|
IGL03267:Tns2
|
APN |
15 |
102,013,813 (GRCm39) |
critical splice donor site |
probably null |
|
|
P0005:Tns2
|
UTSW |
15 |
102,022,491 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0586:Tns2
|
UTSW |
15 |
102,018,020 (GRCm39) |
splice site |
probably benign |
|
|
R0791:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0817:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0818:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0819:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0820:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1451:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1452:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1453:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1454:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1455:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1487:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1510:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Tns2
|
UTSW |
15 |
102,019,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1698:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1772:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1779:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1843:Tns2
|
UTSW |
15 |
102,021,568 (GRCm39) |
splice site |
probably null |
|
|
R1923:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1924:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1927:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1980:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2051:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2087:Tns2
|
UTSW |
15 |
102,015,554 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R2100:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Tns2
|
UTSW |
15 |
102,015,941 (GRCm39) |
missense |
probably benign |
0.27 |
|
R2224:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2225:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2252:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2253:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2290:Tns2
|
UTSW |
15 |
102,020,458 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2304:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2318:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2446:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2447:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2448:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2566:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2567:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2897:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2898:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3159:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Tns2
|
UTSW |
15 |
102,021,771 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R3162:Tns2
|
UTSW |
15 |
102,021,771 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R3162:Tns2
|
UTSW |
15 |
102,021,771 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R3196:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3237:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3426:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3427:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3428:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3695:Tns2
|
UTSW |
15 |
102,021,184 (GRCm39) |
missense |
probably null |
|
|
R3767:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Tns2
|
UTSW |
15 |
102,022,272 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4113:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4157:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4394:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4395:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4441:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4537:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4538:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4541:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4599:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4600:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4602:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4773:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4774:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4775:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4776:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4880:Tns2
|
UTSW |
15 |
102,020,474 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4989:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5014:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5058:Tns2
|
UTSW |
15 |
102,016,295 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5253:Tns2
|
UTSW |
15 |
102,019,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5336:Tns2
|
UTSW |
15 |
102,019,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5351:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5452:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5453:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5629:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5630:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5631:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5685:Tns2
|
UTSW |
15 |
102,015,538 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5844:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Tns2
|
UTSW |
15 |
102,019,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6067:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6079:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6130:Tns2
|
UTSW |
15 |
102,019,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6136:Tns2
|
UTSW |
15 |
102,015,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6138:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6199:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6210:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6426:Tns2
|
UTSW |
15 |
102,015,472 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6544:Tns2
|
UTSW |
15 |
102,022,269 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6594:Tns2
|
UTSW |
15 |
102,018,994 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6596:Tns2
|
UTSW |
15 |
102,018,994 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Tns2
|
UTSW |
15 |
102,011,551 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7061:Tns2
|
UTSW |
15 |
102,012,914 (GRCm39) |
start codon destroyed |
probably null |
|
|
R7070:Tns2
|
UTSW |
15 |
102,012,968 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7110:Tns2
|
UTSW |
15 |
102,013,801 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7410:Tns2
|
UTSW |
15 |
102,018,961 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7447:Tns2
|
UTSW |
15 |
102,019,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7751:Tns2
|
UTSW |
15 |
102,018,163 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8052:Tns2
|
UTSW |
15 |
102,021,280 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8114:Tns2
|
UTSW |
15 |
102,019,825 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8906:Tns2
|
UTSW |
15 |
102,020,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8964:Tns2
|
UTSW |
15 |
102,011,553 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9192:Tns2
|
UTSW |
15 |
102,021,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9273:Tns2
|
UTSW |
15 |
102,021,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9307:Tns2
|
UTSW |
15 |
102,018,996 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9402:Tns2
|
UTSW |
15 |
102,021,623 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9612:Tns2
|
UTSW |
15 |
102,015,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Tns2
|
UTSW |
15 |
102,012,933 (GRCm39) |
missense |
probably benign |
0.03 |
|
U15987:Tns2
|
UTSW |
15 |
102,017,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0009:Tns2
|
UTSW |
15 |
102,020,900 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
X0026:Tns2
|
UTSW |
15 |
102,018,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGATCCTCAGTGCAGTGCTTC -3'
(R):5'- ACTAGCACTGTTGGTGTGGC -3'
Sequencing Primer
(F):5'- CAGTGCAGTGCTTCTTCAGAGC -3'
(R):5'- TTCCTGAGGCCAGCCATTG -3'
|
| Posted On |
2014-09-18 |
Incidental Mutation