Mutagenetix > Incidental Mutation

Incidental Mutation 'R2092:Dmbt1'

231845

Institutional Source

Beutler Lab

Gene Symbol

Dmbt1

Ensembl Gene

ENSMUSG00000047517

Gene Name

deleted in malignant brain tumors 1

Synonyms

CRP-[a], Crpd, gp300, vomeroglandin, CRP-[b], ebnerin, MUCLIN, hensin

MMRRC Submission

040097-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.194) question?

Stock #

R2092 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

131032053-131121630 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 131050018 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Leucine at position 330 (W330L)

Ref Sequence

ENSEMBL: ENSMUSP00000148657 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000084509] [ENSMUST00000124096] [ENSMUST00000208311] [ENSMUST00000213064]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000084509
AA Change: W215L

SMART Domains

Protein: ENSMUSP00000081556
Gene: ENSMUSG00000047517
AA Change: W215L

Domain	Start	End	E-Value	Type
SR	37	137	5.54e-59	SMART
SR	186	286	3.6e-58	SMART
SR	324	424	1.21e-59	SMART
SR	463	563	2.97e-59	SMART
SR	602	702	3.36e-58	SMART
SR	741	841	5.17e-59	SMART
low complexity region	848	879	N/A	INTRINSIC
CUB	884	993	4.22e-41	SMART
CUB	1000	1109	7.35e-41	SMART
CUB	1126	1235	3.73e-42	SMART
CUB	1242	1351	2.02e-38	SMART
SR	1371	1471	3.92e-59	SMART
low complexity region	1476	1488	N/A	INTRINSIC
CUB	1494	1603	6.7e-44	SMART
ZP	1612	1860	8.11e-74	SMART
transmembrane domain	1906	1928	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000124096

SMART Domains

Protein: ENSMUSP00000130971
Gene: ENSMUSG00000030849

Domain	Start	End	E-Value	Type
Pfam:Pkinase	1	118	4.8e-19	PFAM
Pfam:Pkinase_Tyr	1	118	1.7e-50	PFAM
low complexity region	146	160	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000208311
AA Change: W226L

Predicted Effect

probably damaging
Transcript: ENSMUST00000213064
AA Change: W330L

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
PHENOTYPE: Mice homozygous for one null allele display embryonic lethality and an abnormal inner cell mass. Mice homozygous for a different null allele are viable and fertile with an increased susceptibility to induced colitis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 69 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2m	T	A	6: 121,674,937 (GRCm38)	C1321*	probably null	Het
Abca8b	A	G	11: 109,966,708 (GRCm38)	F673L	possibly damaging	Het
Adam19	T	G	11: 46,060,904 (GRCm38)		probably null	Het
AI987944	T	C	7: 41,374,617 (GRCm38)	T313A	possibly damaging	Het
Akap13	A	T	7: 75,610,570 (GRCm38)	I178F	probably benign	Het
Alb	G	GA	5: 90,463,983 (GRCm38)		probably null	Het
Bod1l	A	G	5: 41,831,517 (GRCm38)	S416P	probably damaging	Het
Casr	A	T	16: 36,510,043 (GRCm38)	Y310N	possibly damaging	Het
Cela3a	T	C	4: 137,404,426 (GRCm38)	N152S	probably benign	Het
Chrdl2	T	A	7: 100,020,977 (GRCm38)	C102*	probably null	Het
Col4a4	G	A	1: 82,498,946 (GRCm38)	S554L	unknown	Het
Col6a4	T	C	9: 106,060,331 (GRCm38)	K1392R	probably damaging	Het
Dab1	T	G	4: 104,678,777 (GRCm38)	Y128D	probably damaging	Het
Dars	A	T	1: 128,374,018 (GRCm38)	M293K	probably damaging	Het
Dlec1	T	C	9: 119,121,844 (GRCm38)	F493L	possibly damaging	Het
Dnah11	A	T	12: 118,012,716 (GRCm38)	M831K	possibly damaging	Het
Dock7	T	C	4: 99,009,308 (GRCm38)	N715S	possibly damaging	Het
Edc4	T	A	8: 105,887,528 (GRCm38)	L12Q	probably damaging	Het
Edem2	T	C	2: 155,709,049 (GRCm38)	M333V	probably benign	Het
Fpr-rs4	CAGGAA	CA	17: 18,022,334 (GRCm38)		probably null	Het
Fto	C	A	8: 91,409,687 (GRCm38)	Y194*	probably null	Het
Gnptab	T	G	10: 88,440,305 (GRCm38)	Y1151*	probably null	Het
Grm1	A	G	10: 10,689,225 (GRCm38)	L1113P	probably benign	Het
Hnrnpa0	T	C	13: 58,127,800 (GRCm38)	K172E	probably damaging	Het
Ifitm1	A	G	7: 140,969,514 (GRCm38)	D70G	probably damaging	Het
Irx4	C	A	13: 73,265,486 (GRCm38)	T25K	probably damaging	Het
Kif22	C	T	7: 127,033,630 (GRCm38)	D195N	probably damaging	Het
Lrp2	C	T	2: 69,536,021 (GRCm38)	D245N	probably benign	Het
Lyz1	C	T	10: 117,288,599 (GRCm38)	R144Q	probably benign	Het
Macf1	T	A	4: 123,383,178 (GRCm38)	T6055S	probably damaging	Het
Mrgpra2b	C	T	7: 47,464,160 (GRCm38)	V249I	probably benign	Het
Myh9	G	A	15: 77,764,350 (GRCm38)	Q80*	probably null	Het
Myo6	G	T	9: 80,245,682 (GRCm38)	R199L	probably damaging	Het
Naglu	G	A	11: 101,076,720 (GRCm38)	V499I	possibly damaging	Het
Nfkbie	T	C	17: 45,558,539 (GRCm38)	F140S	probably benign	Het
Olfr1208	A	G	2: 88,897,267 (GRCm38)	F110S	probably damaging	Het
Olfr1454	T	A	19: 13,063,802 (GRCm38)	Y130*	probably null	Het
Olfr510	CAAATA	CA	7: 108,667,662 (GRCm38)		probably null	Het
Olfr598	G	A	7: 103,329,109 (GRCm38)	V208M	probably damaging	Het
Olfr67	A	T	7: 103,788,072 (GRCm38)	F68L	possibly damaging	Het
Olfr935	A	T	9: 38,995,189 (GRCm38)	L82Q	probably damaging	Het
Otop1	A	T	5: 38,299,766 (GRCm38)	I290F	probably damaging	Het
P2rx2	C	T	5: 110,341,141 (GRCm38)	D203N	probably damaging	Het
Pcdhb10	T	A	18: 37,414,187 (GRCm38)	I772N	probably benign	Het
Pnliprp1	A	G	19: 58,741,184 (GRCm38)	H423R	probably benign	Het
Ptk2	A	T	15: 73,236,191 (GRCm38)	Y56*	probably null	Het
Rapgef3	T	C	15: 97,760,723 (GRCm38)	D134G	probably damaging	Het
Scaf11	A	C	15: 96,415,827 (GRCm38)	S1358A	probably damaging	Het
Scn9a	T	C	2: 66,533,376 (GRCm38)	M844V	probably damaging	Het
Sh3tc1	T	C	5: 35,700,658 (GRCm38)	E1121G	probably damaging	Het
Slc25a15	T	C	8: 22,380,934 (GRCm38)	T176A	probably damaging	Het
Slc29a4	T	A	5: 142,718,855 (GRCm38)	I384N	probably damaging	Het
Slc40a1	A	T	1: 45,909,454 (GRCm38)	D555E	probably benign	Het
Smc5	T	C	19: 23,238,899 (GRCm38)	I446V	probably benign	Het
St6gal2	T	C	17: 55,510,266 (GRCm38)	Y477H	probably damaging	Het
Syngr1	A	T	15: 80,115,940 (GRCm38)	Q84L	possibly damaging	Het
Tedc1	T	C	12: 113,157,720 (GRCm38)	L187P	probably damaging	Het
Tg	A	G	15: 66,849,607 (GRCm38)	I322V	probably null	Het
Thap12	T	C	7: 98,716,449 (GRCm38)	V608A	possibly damaging	Het
Tmbim6	T	C	15: 99,402,068 (GRCm38)	S22P	probably damaging	Het
Ttc3	C	T	16: 94,442,832 (GRCm38)	P1232S	probably benign	Het
Upk3a	A	G	15: 85,018,085 (GRCm38)	T38A	probably damaging	Het
Utrn	A	T	10: 12,678,698 (GRCm38)	M1549K	probably benign	Het
Vmn1r176	C	T	7: 23,835,153 (GRCm38)	D192N	probably damaging	Het
Vmn1r198	A	G	13: 22,354,715 (GRCm38)	T35A	possibly damaging	Het
Xkr7	C	T	2: 153,054,063 (GRCm38)	S279L	probably damaging	Het
Zer1	G	A	2: 30,108,274 (GRCm38)	L342F	probably damaging	Het
Zfp641	G	T	15: 98,293,712 (GRCm38)	T31N	probably benign	Het
Zfp74	G	A	7: 29,953,924 (GRCm38)		probably benign	Het

Other mutations in Dmbt1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00091:Dmbt1	APN	7	131,079,540 (GRCm38)	intron	probably benign
IGL00161:Dmbt1	APN	7	131,109,628 (GRCm38)	missense	probably damaging	1.00
IGL00331:Dmbt1	APN	7	131,099,290 (GRCm38)	missense	possibly damaging	0.46
IGL00769:Dmbt1	APN	7	131,082,500 (GRCm38)	missense	probably damaging	0.99
IGL00792:Dmbt1	APN	7	131,097,607 (GRCm38)	missense	possibly damaging	0.66
IGL00823:Dmbt1	APN	7	131,058,158 (GRCm38)	missense	probably benign	0.26
IGL01072:Dmbt1	APN	7	131,085,368 (GRCm38)	splice site	probably benign
IGL01317:Dmbt1	APN	7	131,041,191 (GRCm38)	missense	probably damaging	1.00
IGL01335:Dmbt1	APN	7	131,088,767 (GRCm38)	missense	possibly damaging	0.95
IGL01372:Dmbt1	APN	7	131,103,679 (GRCm38)	missense	possibly damaging	0.90
IGL01511:Dmbt1	APN	7	131,116,728 (GRCm38)	missense	possibly damaging	0.49
IGL01627:Dmbt1	APN	7	131,081,185 (GRCm38)	missense	probably benign	0.14
IGL01890:Dmbt1	APN	7	131,074,419 (GRCm38)	intron	probably benign
IGL02160:Dmbt1	APN	7	131,082,688 (GRCm38)	missense	probably damaging	1.00
IGL02186:Dmbt1	APN	7	131,093,256 (GRCm38)	splice site	probably benign
IGL02197:Dmbt1	APN	7	131,085,422 (GRCm38)	splice site	probably benign
IGL02332:Dmbt1	APN	7	131,066,613 (GRCm38)	intron	probably benign
IGL02427:Dmbt1	APN	7	131,088,085 (GRCm38)	splice site	probably null
IGL02726:Dmbt1	APN	7	131,074,410 (GRCm38)	intron	probably benign
IGL02967:Dmbt1	APN	7	131,071,189 (GRCm38)	missense	possibly damaging	0.70
IGL03003:Dmbt1	APN	7	131,082,679 (GRCm38)	missense	probably benign	0.05
IGL03089:Dmbt1	APN	7	131,111,049 (GRCm38)	missense	probably damaging	0.99
cavity	UTSW	7	131,112,236 (GRCm38)	missense	unknown
lacunar	UTSW	7	131,097,631 (GRCm38)	missense	probably damaging	0.97
BB005:Dmbt1	UTSW	7	131,037,890 (GRCm38)	missense	probably benign	0.16
BB015:Dmbt1	UTSW	7	131,037,890 (GRCm38)	missense	probably benign	0.16
H8562:Dmbt1	UTSW	7	131,112,076 (GRCm38)	nonsense	probably null
K3955:Dmbt1	UTSW	7	131,119,564 (GRCm38)	missense	probably damaging	0.98
R0051:Dmbt1	UTSW	7	131,119,496 (GRCm38)	missense	possibly damaging	0.79
R0051:Dmbt1	UTSW	7	131,119,496 (GRCm38)	missense	possibly damaging	0.79
R0257:Dmbt1	UTSW	7	131,106,393 (GRCm38)	missense	probably damaging	1.00
R0388:Dmbt1	UTSW	7	131,096,049 (GRCm38)	splice site	probably benign
R0427:Dmbt1	UTSW	7	131,040,902 (GRCm38)	nonsense	probably null
R0478:Dmbt1	UTSW	7	131,041,187 (GRCm38)	missense	possibly damaging	0.93
R0502:Dmbt1	UTSW	7	131,097,673 (GRCm38)	splice site	probably null
R0538:Dmbt1	UTSW	7	131,049,901 (GRCm38)	splice site	probably benign
R0626:Dmbt1	UTSW	7	131,102,081 (GRCm38)	missense	probably damaging	0.97
R0631:Dmbt1	UTSW	7	131,097,653 (GRCm38)	missense	possibly damaging	0.90
R0948:Dmbt1	UTSW	7	131,093,117 (GRCm38)	missense	possibly damaging	0.95
R1169:Dmbt1	UTSW	7	131,074,524 (GRCm38)	critical splice donor site	probably null
R1413:Dmbt1	UTSW	7	131,050,214 (GRCm38)	missense	probably damaging	1.00
R1458:Dmbt1	UTSW	7	131,044,487 (GRCm38)	splice site	probably benign
R1463:Dmbt1	UTSW	7	131,109,637 (GRCm38)	critical splice donor site	probably null
R1509:Dmbt1	UTSW	7	131,074,331 (GRCm38)	intron	probably benign
R1990:Dmbt1	UTSW	7	131,058,288 (GRCm38)	missense	probably damaging	0.98
R2018:Dmbt1	UTSW	7	131,110,989 (GRCm38)	missense	possibly damaging	0.93
R2019:Dmbt1	UTSW	7	131,110,989 (GRCm38)	missense	possibly damaging	0.93
R2042:Dmbt1	UTSW	7	131,106,359 (GRCm38)	missense	probably damaging	0.99
R2056:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2057:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2058:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2059:Dmbt1	UTSW	7	131,106,170 (GRCm38)	missense	possibly damaging	0.80
R2061:Dmbt1	UTSW	7	131,099,133 (GRCm38)	missense	possibly damaging	0.66
R2102:Dmbt1	UTSW	7	131,102,032 (GRCm38)	missense	probably damaging	0.97
R2155:Dmbt1	UTSW	7	131,097,575 (GRCm38)	missense	possibly damaging	0.66
R2243:Dmbt1	UTSW	7	131,046,562 (GRCm38)	missense	probably benign	0.03
R2256:Dmbt1	UTSW	7	131,090,494 (GRCm38)	missense	probably benign	0.01
R2391:Dmbt1	UTSW	7	131,106,468 (GRCm38)	missense	probably damaging	1.00
R2394:Dmbt1	UTSW	7	131,094,734 (GRCm38)	nonsense	probably null
R3014:Dmbt1	UTSW	7	131,032,097 (GRCm38)	intron	probably benign
R3155:Dmbt1	UTSW	7	131,050,157 (GRCm38)	nonsense	probably null
R3176:Dmbt1	UTSW	7	131,088,071 (GRCm38)	missense	probably benign	0.19
R3276:Dmbt1	UTSW	7	131,088,071 (GRCm38)	missense	probably benign	0.19
R3442:Dmbt1	UTSW	7	131,106,249 (GRCm38)	missense	probably damaging	1.00
R3807:Dmbt1	UTSW	7	131,112,090 (GRCm38)	missense	possibly damaging	0.77
R4060:Dmbt1	UTSW	7	131,074,202 (GRCm38)	intron	probably benign
R4396:Dmbt1	UTSW	7	131,116,632 (GRCm38)	missense	probably damaging	0.98
R4453:Dmbt1	UTSW	7	131,040,934 (GRCm38)	missense	probably damaging	1.00
R5001:Dmbt1	UTSW	7	131,050,012 (GRCm38)	missense	probably damaging	1.00
R5051:Dmbt1	UTSW	7	131,094,742 (GRCm38)	missense	probably benign	0.01
R5156:Dmbt1	UTSW	7	131,097,670 (GRCm38)	critical splice donor site	probably null
R5225:Dmbt1	UTSW	7	131,094,735 (GRCm38)	missense	possibly damaging	0.84
R5281:Dmbt1	UTSW	7	131,082,619 (GRCm38)	missense	probably damaging	1.00
R5308:Dmbt1	UTSW	7	131,041,021 (GRCm38)	missense	probably damaging	1.00
R5447:Dmbt1	UTSW	7	131,119,511 (GRCm38)	missense	probably damaging	0.99
R5467:Dmbt1	UTSW	7	131,040,993 (GRCm38)	missense	probably damaging	1.00
R5497:Dmbt1	UTSW	7	131,063,403 (GRCm38)	intron	probably benign
R5526:Dmbt1	UTSW	7	131,041,190 (GRCm38)	missense	probably damaging	1.00
R5554:Dmbt1	UTSW	7	131,099,300 (GRCm38)	nonsense	probably null
R5566:Dmbt1	UTSW	7	131,106,273 (GRCm38)	missense	probably damaging	1.00
R5595:Dmbt1	UTSW	7	131,054,067 (GRCm38)	missense	probably benign	0.17
R6154:Dmbt1	UTSW	7	131,109,641 (GRCm38)	splice site	probably null
R6188:Dmbt1	UTSW	7	131,097,631 (GRCm38)	missense	probably damaging	0.97
R6214:Dmbt1	UTSW	7	131,066,733 (GRCm38)	missense	possibly damaging	0.95
R6215:Dmbt1	UTSW	7	131,066,733 (GRCm38)	missense	possibly damaging	0.95
R6391:Dmbt1	UTSW	7	131,058,254 (GRCm38)	missense	probably damaging	1.00
R6397:Dmbt1	UTSW	7	131,103,578 (GRCm38)	missense	possibly damaging	0.46
R6436:Dmbt1	UTSW	7	131,116,641 (GRCm38)	missense	probably benign	0.01
R6603:Dmbt1	UTSW	7	131,046,510 (GRCm38)	splice site	probably null
R6719:Dmbt1	UTSW	7	131,119,603 (GRCm38)	missense	possibly damaging	0.83
R6781:Dmbt1	UTSW	7	131,046,561 (GRCm38)	missense	probably benign	0.16
R7148:Dmbt1	UTSW	7	131,066,734 (GRCm38)	nonsense	probably null
R7191:Dmbt1	UTSW	7	131,044,520 (GRCm38)	missense	unknown
R7269:Dmbt1	UTSW	7	131,066,621 (GRCm38)	missense	unknown
R7288:Dmbt1	UTSW	7	131,083,789 (GRCm38)	nonsense	probably null
R7296:Dmbt1	UTSW	7	131,112,132 (GRCm38)	missense	unknown
R7349:Dmbt1	UTSW	7	131,041,124 (GRCm38)	missense	unknown
R7386:Dmbt1	UTSW	7	131,112,236 (GRCm38)	missense	unknown
R7428:Dmbt1	UTSW	7	131,108,463 (GRCm38)	missense	possibly damaging	0.53
R7481:Dmbt1	UTSW	7	131,079,511 (GRCm38)	critical splice acceptor site	probably null
R7486:Dmbt1	UTSW	7	131,066,462 (GRCm38)	missense	unknown
R7513:Dmbt1	UTSW	7	131,090,512 (GRCm38)	missense	unknown
R7553:Dmbt1	UTSW	7	131,104,867 (GRCm38)	missense	unknown
R7567:Dmbt1	UTSW	7	131,061,363 (GRCm38)	splice site	probably null
R7584:Dmbt1	UTSW	7	131,088,751 (GRCm38)	nonsense	probably null
R7736:Dmbt1	UTSW	7	131,116,896 (GRCm38)	missense	unknown
R7758:Dmbt1	UTSW	7	131,121,197 (GRCm38)	missense	unknown
R7928:Dmbt1	UTSW	7	131,037,890 (GRCm38)	missense	probably benign	0.16
R8080:Dmbt1	UTSW	7	131,088,770 (GRCm38)	missense	unknown
R8098:Dmbt1	UTSW	7	131,108,459 (GRCm38)	nonsense	probably null
R8125:Dmbt1	UTSW	7	131,099,223 (GRCm38)	missense	unknown
R8177:Dmbt1	UTSW	7	131,106,432 (GRCm38)	missense	possibly damaging	0.46
R8350:Dmbt1	UTSW	7	131,085,417 (GRCm38)	critical splice donor site	probably null
R8366:Dmbt1	UTSW	7	131,066,600 (GRCm38)	missense	unknown
R8378:Dmbt1	UTSW	7	131,106,465 (GRCm38)	missense	probably damaging	0.96
R8399:Dmbt1	UTSW	7	131,082,587 (GRCm38)	missense	unknown
R8400:Dmbt1	UTSW	7	131,082,587 (GRCm38)	missense	unknown
R8445:Dmbt1	UTSW	7	131,090,380 (GRCm38)	missense	unknown
R8450:Dmbt1	UTSW	7	131,085,417 (GRCm38)	critical splice donor site	probably null
R8511:Dmbt1	UTSW	7	131,102,012 (GRCm38)	missense	unknown
R8688:Dmbt1	UTSW	7	131,058,254 (GRCm38)	missense	unknown
R8850:Dmbt1	UTSW	7	131,090,404 (GRCm38)	missense	unknown
R8852:Dmbt1	UTSW	7	131,041,123 (GRCm38)	missense	unknown
R8871:Dmbt1	UTSW	7	131,116,868 (GRCm38)	missense	unknown
R8943:Dmbt1	UTSW	7	131,119,643 (GRCm38)	missense	possibly damaging	0.68
R8978:Dmbt1	UTSW	7	131,037,881 (GRCm38)	missense	possibly damaging	0.53
R9004:Dmbt1	UTSW	7	131,112,069 (GRCm38)	missense	unknown
R9020:Dmbt1	UTSW	7	131,111,058 (GRCm38)	missense	possibly damaging	0.86
R9088:Dmbt1	UTSW	7	131,116,689 (GRCm38)	missense	unknown
R9230:Dmbt1	UTSW	7	131,037,912 (GRCm38)	missense	probably benign	0.01
R9304:Dmbt1	UTSW	7	131,099,125 (GRCm38)	missense	unknown
R9377:Dmbt1	UTSW	7	131,093,102 (GRCm38)	missense	unknown
R9428:Dmbt1	UTSW	7	131,066,478 (GRCm38)	missense	unknown
R9474:Dmbt1	UTSW	7	131,074,257 (GRCm38)	missense	unknown
R9573:Dmbt1	UTSW	7	131,056,180 (GRCm38)	critical splice donor site	probably null
R9675:Dmbt1	UTSW	7	131,110,923 (GRCm38)	missense	probably damaging	0.98
R9689:Dmbt1	UTSW	7	131,058,285 (GRCm38)	missense	unknown
R9781:Dmbt1	UTSW	7	131,037,869 (GRCm38)	missense	probably benign	0.00
X0024:Dmbt1	UTSW	7	131,112,248 (GRCm38)	nonsense	probably null
X0062:Dmbt1	UTSW	7	131,094,851 (GRCm38)	missense	possibly damaging	0.81
Z1176:Dmbt1	UTSW	7	131,088,812 (GRCm38)	missense	unknown
Z1177:Dmbt1	UTSW	7	131,082,485 (GRCm38)	critical splice acceptor site	probably null

Predicted Primers

PCR Primer
(F):5'- TCAGTGTCCCACAAAGTGTAC -3'
(R):5'- CCTGAACAGATGACTCCAGC -3'

Sequencing Primer
(F):5'- GTGTCCCACAAAGTGTACAAGGTC -3'
(R):5'- TGTCCACAGTTATGAGAGAGCC -3'

Posted On

2014-09-18