Incidental Mutation 'R2115:Abca16'
| ID |
233028 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca16
|
| Ensembl Gene |
ENSMUSG00000051900 |
| Gene Name |
ATP-binding cassette, sub-family A member 16 |
| Synonyms |
|
| MMRRC Submission |
040119-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2115 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
120008870-120144036 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 120139868 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Alanine
at position 1510
(E1510A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000061094
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056042]
[ENSMUST00000120490]
|
| AlphaFold |
E9PWJ7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000056042
AA Change: E1510A
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000061094
Gene: ENSMUSG00000051900
AA Change: E1510A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
26 |
455 |
2.7e-23 |
PFAM |
|
AAA
|
537 |
720 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
898 |
1287 |
4.6e-25 |
PFAM |
|
low complexity region
|
1325 |
1336 |
N/A |
INTRINSIC |
|
low complexity region
|
1342 |
1353 |
N/A |
INTRINSIC |
|
AAA
|
1378 |
1563 |
4.23e-6 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000120490
AA Change: E1511A
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000112736
Gene: ENSMUSG00000051900
AA Change: E1511A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
25 |
456 |
2.4e-22 |
PFAM |
|
AAA
|
538 |
721 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
899 |
1288 |
1.1e-27 |
PFAM |
|
low complexity region
|
1326 |
1337 |
N/A |
INTRINSIC |
|
low complexity region
|
1343 |
1354 |
N/A |
INTRINSIC |
|
AAA
|
1379 |
1564 |
4.23e-6 |
SMART |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
98% (95/97) |
| Allele List at MGI |
All alleles(4) : Targeted(3) Gene trapped(1)
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatk |
T |
C |
11: 119,900,562 (GRCm39) |
T1195A |
probably benign |
Het |
| Abca12 |
A |
T |
1: 71,283,930 (GRCm39) |
N2547K |
probably benign |
Het |
| Adam5 |
A |
G |
8: 25,234,161 (GRCm39) |
|
probably benign |
Het |
| Akna |
G |
A |
4: 63,313,397 (GRCm39) |
P242L |
probably benign |
Het |
| Akr1b7 |
G |
A |
6: 34,395,929 (GRCm39) |
A144T |
possibly damaging |
Het |
| Ankhd1 |
T |
A |
18: 36,767,361 (GRCm39) |
S1167T |
probably damaging |
Het |
| Arf5 |
C |
T |
6: 28,424,783 (GRCm39) |
Q71* |
probably null |
Het |
| Ark2n |
T |
C |
18: 77,762,168 (GRCm39) |
D48G |
possibly damaging |
Het |
| Arl15 |
C |
T |
13: 114,104,196 (GRCm39) |
S111F |
probably damaging |
Het |
| Atxn1l |
C |
T |
8: 110,459,240 (GRCm39) |
A341T |
probably benign |
Het |
| Birc7 |
C |
A |
2: 180,572,642 (GRCm39) |
Q138K |
possibly damaging |
Het |
| Blvra |
G |
T |
2: 126,927,989 (GRCm39) |
E80* |
probably null |
Het |
| Ccdc148 |
T |
C |
2: 58,892,128 (GRCm39) |
E188G |
probably damaging |
Het |
| Chad |
C |
T |
11: 94,459,052 (GRCm39) |
A318V |
probably benign |
Het |
| Cntfr |
A |
G |
4: 41,663,534 (GRCm39) |
|
probably null |
Het |
| Dnah17 |
C |
T |
11: 118,010,628 (GRCm39) |
C230Y |
probably benign |
Het |
| Dnmt3l |
C |
A |
10: 77,899,130 (GRCm39) |
L110I |
probably damaging |
Het |
| Dusp11 |
T |
C |
6: 85,935,651 (GRCm39) |
D74G |
probably damaging |
Het |
| Duxf4 |
T |
C |
10: 58,072,073 (GRCm39) |
D47G |
possibly damaging |
Het |
| Eif3m |
T |
C |
2: 104,837,141 (GRCm39) |
T61A |
probably damaging |
Het |
| Esyt1 |
T |
A |
10: 128,357,973 (GRCm39) |
D212V |
probably damaging |
Het |
| Exoc4 |
T |
A |
6: 33,324,760 (GRCm39) |
N351K |
possibly damaging |
Het |
| F13a1 |
A |
T |
13: 37,172,831 (GRCm39) |
I183N |
probably damaging |
Het |
| Fam83f |
T |
G |
15: 80,576,468 (GRCm39) |
V373G |
possibly damaging |
Het |
| Fam83h |
A |
T |
15: 75,874,146 (GRCm39) |
Y1064N |
probably damaging |
Het |
| Flrt3 |
G |
T |
2: 140,503,423 (GRCm39) |
N68K |
probably damaging |
Het |
| Fut7 |
C |
A |
2: 25,315,343 (GRCm39) |
Y153* |
probably null |
Het |
| Gm10277 |
TC |
T |
11: 77,676,828 (GRCm39) |
|
probably null |
Het |
| Gm1527 |
T |
C |
3: 28,972,098 (GRCm39) |
L405P |
probably benign |
Het |
| Heatr6 |
T |
A |
11: 83,648,281 (GRCm39) |
|
probably benign |
Het |
| Herc2 |
T |
C |
7: 55,835,576 (GRCm39) |
|
probably benign |
Het |
| Ints14 |
T |
G |
9: 64,887,077 (GRCm39) |
L336R |
probably damaging |
Het |
| Irak1 |
G |
T |
X: 73,066,218 (GRCm39) |
P197Q |
possibly damaging |
Het |
| Kat7 |
C |
T |
11: 95,194,120 (GRCm39) |
R60Q |
probably benign |
Het |
| Katnal2 |
T |
C |
18: 77,067,787 (GRCm39) |
R385G |
probably damaging |
Het |
| Kcnt2 |
G |
T |
1: 140,480,701 (GRCm39) |
L755F |
probably damaging |
Het |
| Kif4 |
A |
G |
X: 99,709,323 (GRCm39) |
S315G |
probably benign |
Het |
| Kifc3 |
A |
G |
8: 95,835,341 (GRCm39) |
Y178H |
probably damaging |
Het |
| Krit1 |
A |
T |
5: 3,872,108 (GRCm39) |
R378* |
probably null |
Het |
| L3mbtl1 |
T |
A |
2: 162,801,990 (GRCm39) |
|
probably null |
Het |
| Lama3 |
C |
A |
18: 12,535,906 (GRCm39) |
T204N |
possibly damaging |
Het |
| Lama5 |
A |
G |
2: 179,828,678 (GRCm39) |
C2090R |
probably damaging |
Het |
| Mb |
G |
T |
15: 76,906,759 (GRCm39) |
Q9K |
probably benign |
Het |
| Mipep |
T |
C |
14: 61,024,829 (GRCm39) |
V90A |
probably damaging |
Het |
| Myo3a |
A |
T |
2: 22,250,342 (GRCm39) |
I70F |
probably damaging |
Het |
| Napa |
A |
G |
7: 15,848,134 (GRCm39) |
D217G |
possibly damaging |
Het |
| Nectin2 |
T |
C |
7: 19,451,489 (GRCm39) |
D515G |
probably damaging |
Het |
| Nkx2-6 |
T |
A |
14: 69,409,288 (GRCm39) |
V13E |
probably damaging |
Het |
| Nmi |
T |
C |
2: 51,838,719 (GRCm39) |
T272A |
probably benign |
Het |
| Nptx2 |
G |
C |
5: 144,492,216 (GRCm39) |
G331A |
probably damaging |
Het |
| Or2q1 |
A |
G |
6: 42,794,431 (GRCm39) |
T9A |
possibly damaging |
Het |
| Or4c122 |
T |
C |
2: 89,079,874 (GRCm39) |
I55V |
probably damaging |
Het |
| Or5h17 |
T |
C |
16: 58,820,783 (GRCm39) |
L245P |
possibly damaging |
Het |
| Or7g34 |
T |
C |
9: 19,478,618 (GRCm39) |
T18A |
probably benign |
Het |
| Parp14 |
T |
C |
16: 35,678,904 (GRCm39) |
T355A |
probably benign |
Het |
| Pcdh12 |
T |
C |
18: 38,417,039 (GRCm39) |
T29A |
probably damaging |
Het |
| Pced1b |
T |
A |
15: 97,282,505 (GRCm39) |
C181* |
probably null |
Het |
| Phka1 |
C |
T |
X: 101,653,807 (GRCm39) |
R290H |
probably damaging |
Het |
| Pick1 |
T |
A |
15: 79,139,781 (GRCm39) |
|
probably benign |
Het |
| Pitrm1 |
A |
T |
13: 6,607,809 (GRCm39) |
Y268F |
probably damaging |
Het |
| Polr2h |
T |
C |
16: 20,537,737 (GRCm39) |
|
probably benign |
Het |
| Ppfia2 |
A |
T |
10: 106,597,972 (GRCm39) |
K178N |
probably damaging |
Het |
| Prkag1 |
T |
C |
15: 98,712,433 (GRCm39) |
Y133C |
probably damaging |
Het |
| Ptk2 |
A |
G |
15: 73,114,255 (GRCm39) |
V701A |
possibly damaging |
Het |
| Ptpra |
G |
T |
2: 130,381,655 (GRCm39) |
R372L |
probably damaging |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Qrich2 |
A |
G |
11: 116,337,982 (GRCm39) |
V1887A |
probably damaging |
Het |
| Ralgapa1 |
T |
C |
12: 55,833,134 (GRCm39) |
|
probably null |
Het |
| Rassf9 |
A |
G |
10: 102,380,806 (GRCm39) |
T63A |
probably benign |
Het |
| Rdh11 |
G |
T |
12: 79,222,996 (GRCm39) |
Q292K |
probably benign |
Het |
| Rere |
C |
A |
4: 150,697,018 (GRCm39) |
|
probably benign |
Het |
| Rgs18 |
G |
T |
1: 144,629,629 (GRCm39) |
T210K |
possibly damaging |
Het |
| Rnf213 |
A |
G |
11: 119,318,839 (GRCm39) |
N1099S |
probably benign |
Het |
| Ros1 |
T |
C |
10: 52,004,651 (GRCm39) |
I969V |
probably benign |
Het |
| Rrh |
T |
C |
3: 129,604,336 (GRCm39) |
I288M |
probably damaging |
Het |
| Rrp12 |
C |
T |
19: 41,879,533 (GRCm39) |
V174I |
probably benign |
Het |
| Rtf1 |
T |
A |
2: 119,535,999 (GRCm39) |
H184Q |
probably benign |
Het |
| Sbk3 |
A |
G |
7: 4,970,415 (GRCm39) |
L318S |
possibly damaging |
Het |
| Scn9a |
T |
C |
2: 66,314,396 (GRCm39) |
E1774G |
probably damaging |
Het |
| Sec11c |
A |
T |
18: 65,933,720 (GRCm39) |
T9S |
probably benign |
Het |
| Sec23ip |
G |
A |
7: 128,364,185 (GRCm39) |
V488I |
probably benign |
Het |
| Serpine3 |
T |
C |
14: 62,910,459 (GRCm39) |
L184P |
probably damaging |
Het |
| Slc26a2 |
T |
C |
18: 61,331,896 (GRCm39) |
T512A |
possibly damaging |
Het |
| Slc49a4 |
T |
C |
16: 35,518,309 (GRCm39) |
D468G |
probably benign |
Het |
| Smpd4 |
T |
C |
16: 17,444,729 (GRCm39) |
Y118H |
probably benign |
Het |
| Tcof1 |
T |
C |
18: 60,965,857 (GRCm39) |
E415G |
possibly damaging |
Het |
| Ttc33 |
G |
A |
15: 5,241,534 (GRCm39) |
V120I |
probably benign |
Het |
| Usp20 |
T |
A |
2: 30,906,317 (GRCm39) |
C562S |
probably damaging |
Het |
| Utp20 |
T |
C |
10: 88,621,865 (GRCm39) |
D1136G |
probably benign |
Het |
| Vgll1 |
A |
C |
X: 56,137,790 (GRCm39) |
K53T |
probably damaging |
Het |
| Yars1 |
T |
G |
4: 129,101,716 (GRCm39) |
|
probably null |
Het |
| Zfp472 |
A |
G |
17: 33,196,988 (GRCm39) |
I354M |
possibly damaging |
Het |
| Zfp786 |
A |
G |
6: 47,803,931 (GRCm39) |
V37A |
probably damaging |
Het |
|
| Other mutations in Abca16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00417:Abca16
|
APN |
7 |
120,022,982 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL00590:Abca16
|
APN |
7 |
120,023,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01320:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01322:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01613:Abca16
|
APN |
7 |
120,140,500 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01774:Abca16
|
APN |
7 |
120,021,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL01774:Abca16
|
APN |
7 |
120,077,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01797:Abca16
|
APN |
7 |
120,113,760 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02406:Abca16
|
APN |
7 |
120,139,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02437:Abca16
|
APN |
7 |
120,132,952 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02541:Abca16
|
APN |
7 |
120,113,881 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02576:Abca16
|
APN |
7 |
120,032,678 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02578:Abca16
|
APN |
7 |
120,023,179 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03156:Abca16
|
APN |
7 |
120,023,074 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL03381:Abca16
|
APN |
7 |
120,127,041 (GRCm39) |
missense |
probably benign |
0.12 |
|
PIT4802001:Abca16
|
UTSW |
7 |
120,139,351 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0024:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0123:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0134:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0225:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0346:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0355:Abca16
|
UTSW |
7 |
120,023,021 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0358:Abca16
|
UTSW |
7 |
120,143,939 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0525:Abca16
|
UTSW |
7 |
120,065,033 (GRCm39) |
nonsense |
probably null |
|
|
R0617:Abca16
|
UTSW |
7 |
120,032,834 (GRCm39) |
splice site |
probably benign |
|
|
R0625:Abca16
|
UTSW |
7 |
120,035,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Abca16
|
UTSW |
7 |
120,065,007 (GRCm39) |
missense |
probably benign |
0.42 |
|
R1445:Abca16
|
UTSW |
7 |
120,119,256 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1535:Abca16
|
UTSW |
7 |
120,139,928 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1567:Abca16
|
UTSW |
7 |
120,030,352 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1694:Abca16
|
UTSW |
7 |
120,119,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1860:Abca16
|
UTSW |
7 |
120,133,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1876:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1913:Abca16
|
UTSW |
7 |
120,140,463 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1940:Abca16
|
UTSW |
7 |
120,032,832 (GRCm39) |
splice site |
probably benign |
|
|
R2042:Abca16
|
UTSW |
7 |
120,143,941 (GRCm39) |
missense |
probably benign |
|
|
R2122:Abca16
|
UTSW |
7 |
120,119,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2265:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2267:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2269:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2993:Abca16
|
UTSW |
7 |
120,134,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3055:Abca16
|
UTSW |
7 |
120,035,074 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3956:Abca16
|
UTSW |
7 |
120,126,975 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4114:Abca16
|
UTSW |
7 |
120,126,290 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4441:Abca16
|
UTSW |
7 |
120,127,024 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4601:Abca16
|
UTSW |
7 |
120,035,920 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4706:Abca16
|
UTSW |
7 |
120,064,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4807:Abca16
|
UTSW |
7 |
120,139,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Abca16
|
UTSW |
7 |
120,074,702 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4937:Abca16
|
UTSW |
7 |
120,126,309 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5152:Abca16
|
UTSW |
7 |
120,139,846 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5257:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5258:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5330:Abca16
|
UTSW |
7 |
120,102,600 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5388:Abca16
|
UTSW |
7 |
120,139,969 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Abca16
|
UTSW |
7 |
120,143,995 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5810:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6161:Abca16
|
UTSW |
7 |
120,139,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6313:Abca16
|
UTSW |
7 |
120,126,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6485:Abca16
|
UTSW |
7 |
120,026,390 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Abca16
|
UTSW |
7 |
120,076,995 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6772:Abca16
|
UTSW |
7 |
120,126,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Abca16
|
UTSW |
7 |
120,119,332 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6899:Abca16
|
UTSW |
7 |
120,126,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Abca16
|
UTSW |
7 |
120,140,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6990:Abca16
|
UTSW |
7 |
120,126,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7059:Abca16
|
UTSW |
7 |
120,020,971 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7144:Abca16
|
UTSW |
7 |
120,032,796 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7146:Abca16
|
UTSW |
7 |
120,126,974 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7193:Abca16
|
UTSW |
7 |
120,026,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7308:Abca16
|
UTSW |
7 |
120,022,993 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7449:Abca16
|
UTSW |
7 |
120,035,131 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7571:Abca16
|
UTSW |
7 |
120,119,211 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7617:Abca16
|
UTSW |
7 |
120,102,694 (GRCm39) |
nonsense |
probably null |
|
|
R7646:Abca16
|
UTSW |
7 |
120,113,937 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7750:Abca16
|
UTSW |
7 |
120,113,928 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7763:Abca16
|
UTSW |
7 |
120,113,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7840:Abca16
|
UTSW |
7 |
120,074,689 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7946:Abca16
|
UTSW |
7 |
120,126,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8018:Abca16
|
UTSW |
7 |
120,132,866 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8170:Abca16
|
UTSW |
7 |
120,065,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8413:Abca16
|
UTSW |
7 |
120,023,123 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8461:Abca16
|
UTSW |
7 |
120,035,918 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8858:Abca16
|
UTSW |
7 |
120,052,327 (GRCm39) |
missense |
probably benign |
|
|
R8881:Abca16
|
UTSW |
7 |
120,074,794 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9272:Abca16
|
UTSW |
7 |
120,076,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9303:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9305:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9320:Abca16
|
UTSW |
7 |
120,139,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9413:Abca16
|
UTSW |
7 |
120,126,422 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9512:Abca16
|
UTSW |
7 |
120,022,963 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9559:Abca16
|
UTSW |
7 |
120,021,019 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9615:Abca16
|
UTSW |
7 |
120,126,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9641:Abca16
|
UTSW |
7 |
120,126,308 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9643:Abca16
|
UTSW |
7 |
120,065,023 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9674:Abca16
|
UTSW |
7 |
120,074,668 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9714:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9799:Abca16
|
UTSW |
7 |
120,132,998 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9800:Abca16
|
UTSW |
7 |
120,119,283 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
RF020:Abca16
|
UTSW |
7 |
120,132,880 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
X0066:Abca16
|
UTSW |
7 |
120,102,609 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATTTGCAACTTGGATGGGG -3'
(R):5'- TACTGACTCAGTCCTGGCAG -3'
Sequencing Primer
(F):5'- CAACTTGGATGGGGGTTAACC -3'
(R):5'- GTCCTGGCAGAAATTAATTTCATCC -3'
|
| Posted On |
2014-09-18 |
Incidental Mutation