Incidental Mutation 'R0194:Fam186a'
| ID |
23329 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fam186a
|
| Ensembl Gene |
ENSMUSG00000045350 |
| Gene Name |
family with sequence similarity 186, member A |
| Synonyms |
LOC380973, 1700030F18Rik |
| MMRRC Submission |
038453-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
R0194 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
99816229-99864942 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 99839644 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 2200
(T2200I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097783
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100209]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100209
AA Change: T2200I
PolyPhen 2
Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000097783
Gene: ENSMUSG00000045350
AA Change: T2200I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
21 |
N/A |
INTRINSIC |
|
Blast:FBG
|
44 |
222 |
4e-48 |
BLAST |
|
coiled coil region
|
292 |
340 |
N/A |
INTRINSIC |
|
low complexity region
|
423 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
446 |
458 |
N/A |
INTRINSIC |
|
low complexity region
|
632 |
644 |
N/A |
INTRINSIC |
|
low complexity region
|
702 |
713 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
743 |
1156 |
1.05e-58 |
PROSPERO |
|
internal_repeat_1
|
833 |
1270 |
7.71e-59 |
PROSPERO |
|
low complexity region
|
1271 |
1285 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1327 |
1338 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1365 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1384 |
1395 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1414 |
N/A |
INTRINSIC |
|
low complexity region
|
1423 |
1437 |
N/A |
INTRINSIC |
|
low complexity region
|
1441 |
1452 |
N/A |
INTRINSIC |
|
low complexity region
|
1460 |
1471 |
N/A |
INTRINSIC |
|
low complexity region
|
1479 |
1490 |
N/A |
INTRINSIC |
|
low complexity region
|
1498 |
1509 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1532 |
N/A |
INTRINSIC |
|
low complexity region
|
1536 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1555 |
1566 |
N/A |
INTRINSIC |
|
low complexity region
|
1574 |
1585 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1586 |
1981 |
7.71e-59 |
PROSPERO |
|
internal_repeat_2
|
1737 |
2197 |
1.05e-58 |
PROSPERO |
|
low complexity region
|
2367 |
2378 |
N/A |
INTRINSIC |
|
low complexity region
|
2549 |
2564 |
N/A |
INTRINSIC |
|
low complexity region
|
2644 |
2655 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000104255
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177831
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180309
|
| Meta Mutation Damage Score |
0.4309 |
| Coding Region Coverage |
- 1x: 98.6%
- 3x: 97.3%
- 10x: 91.4%
- 20x: 70.1%
|
| Validation Efficiency |
91% (439/482) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930553M12Rik |
T |
A |
4: 88,786,480 (GRCm39) |
D46V |
unknown |
Het |
| Abcb9 |
A |
G |
5: 124,215,358 (GRCm39) |
V461A |
probably damaging |
Het |
| Ackr4 |
T |
A |
9: 103,976,679 (GRCm39) |
L89F |
probably benign |
Het |
| Acsf2 |
T |
C |
11: 94,452,196 (GRCm39) |
T449A |
probably benign |
Het |
| Acsl4 |
C |
G |
X: 141,116,714 (GRCm39) |
G489R |
probably damaging |
Het |
| Actl6a |
T |
A |
3: 32,779,469 (GRCm39) |
I399N |
probably damaging |
Het |
| Adamts19 |
G |
A |
18: 59,144,220 (GRCm39) |
C934Y |
probably null |
Het |
| Adsl |
A |
G |
15: 80,845,561 (GRCm39) |
E40G |
possibly damaging |
Het |
| Alppl2 |
T |
G |
1: 87,016,465 (GRCm39) |
D203A |
probably damaging |
Het |
| Asb10 |
C |
A |
5: 24,742,930 (GRCm39) |
A268S |
probably benign |
Het |
| Atp9a |
T |
C |
2: 168,485,805 (GRCm39) |
S832G |
probably benign |
Het |
| Bckdha |
A |
T |
7: 25,330,875 (GRCm39) |
I297N |
probably damaging |
Het |
| Blm |
G |
A |
7: 80,114,694 (GRCm39) |
|
probably benign |
Het |
| C9orf72 |
T |
A |
4: 35,197,207 (GRCm39) |
D122V |
probably damaging |
Het |
| Cacna1h |
A |
G |
17: 25,599,898 (GRCm39) |
|
probably benign |
Het |
| Camsap2 |
G |
A |
1: 136,220,686 (GRCm39) |
Q298* |
probably null |
Het |
| Ccdc38 |
A |
T |
10: 93,401,774 (GRCm39) |
K145* |
probably null |
Het |
| Cfap45 |
C |
T |
1: 172,368,894 (GRCm39) |
T434M |
probably benign |
Het |
| Cfap54 |
A |
T |
10: 92,870,524 (GRCm39) |
|
probably benign |
Het |
| Clcn6 |
G |
A |
4: 148,097,213 (GRCm39) |
P618L |
probably damaging |
Het |
| Copg1 |
T |
C |
6: 87,881,179 (GRCm39) |
|
probably benign |
Het |
| Dctd |
T |
A |
8: 48,565,113 (GRCm39) |
N79K |
probably benign |
Het |
| Dgkq |
A |
G |
5: 108,802,510 (GRCm39) |
|
probably benign |
Het |
| Dntt |
A |
T |
19: 41,027,409 (GRCm39) |
T159S |
possibly damaging |
Het |
| Doc2g |
G |
A |
19: 4,053,656 (GRCm39) |
R29Q |
probably benign |
Het |
| Dsg3 |
A |
G |
18: 20,673,199 (GRCm39) |
T957A |
probably damaging |
Het |
| Eif3c |
T |
A |
7: 126,157,795 (GRCm39) |
|
probably benign |
Het |
| Ephb3 |
T |
A |
16: 21,036,859 (GRCm39) |
D107E |
probably benign |
Het |
| Esrrb |
A |
T |
12: 86,517,255 (GRCm39) |
D108V |
probably damaging |
Het |
| Exo1 |
A |
G |
1: 175,719,596 (GRCm39) |
K214E |
probably damaging |
Het |
| Fam227a |
C |
T |
15: 79,524,870 (GRCm39) |
W194* |
probably null |
Het |
| Foxn4 |
A |
G |
5: 114,397,809 (GRCm39) |
|
probably null |
Het |
| Gabbr2 |
T |
C |
4: 46,787,565 (GRCm39) |
K366R |
possibly damaging |
Het |
| Garem2 |
T |
A |
5: 30,318,928 (GRCm39) |
V130E |
probably damaging |
Het |
| Grin2b |
A |
G |
6: 135,756,303 (GRCm39) |
F474S |
probably damaging |
Het |
| H2-M10.6 |
G |
T |
17: 37,124,934 (GRCm39) |
V284F |
probably damaging |
Het |
| Helz2 |
C |
A |
2: 180,874,552 (GRCm39) |
G1981C |
probably damaging |
Het |
| Hivep1 |
G |
T |
13: 42,308,911 (GRCm39) |
V384F |
probably damaging |
Het |
| Hmox1 |
A |
G |
8: 75,823,736 (GRCm39) |
T135A |
probably damaging |
Het |
| Hpse |
T |
C |
5: 100,867,378 (GRCm39) |
D28G |
probably benign |
Het |
| Itm2b |
G |
T |
14: 73,602,058 (GRCm39) |
D213E |
probably benign |
Het |
| Jakmip1 |
T |
A |
5: 37,291,627 (GRCm39) |
M692K |
possibly damaging |
Het |
| Kdm3a |
T |
C |
6: 71,601,578 (GRCm39) |
Q151R |
probably null |
Het |
| Limch1 |
C |
A |
5: 67,156,616 (GRCm39) |
A517E |
probably benign |
Het |
| Lrit1 |
T |
A |
14: 36,783,677 (GRCm39) |
L335Q |
probably damaging |
Het |
| Lrrc37a |
A |
G |
11: 103,390,616 (GRCm39) |
V1603A |
possibly damaging |
Het |
| Mbtps1 |
T |
A |
8: 120,262,108 (GRCm39) |
N347I |
probably damaging |
Het |
| Mier1 |
A |
T |
4: 102,996,716 (GRCm39) |
|
probably null |
Het |
| Mt2 |
A |
T |
8: 94,899,476 (GRCm39) |
M1L |
probably damaging |
Het |
| Mug1 |
A |
T |
6: 121,817,066 (GRCm39) |
E45V |
probably damaging |
Het |
| Mybphl |
A |
G |
3: 108,281,484 (GRCm39) |
K67E |
probably benign |
Het |
| Myh4 |
A |
G |
11: 67,143,162 (GRCm39) |
K1030R |
probably damaging |
Het |
| Myl3 |
T |
A |
9: 110,598,189 (GRCm39) |
D176E |
probably benign |
Het |
| Ncapg2 |
A |
G |
12: 116,384,303 (GRCm39) |
|
probably null |
Het |
| Ndor1 |
T |
C |
2: 25,138,718 (GRCm39) |
|
probably null |
Het |
| Nedd4 |
T |
G |
9: 72,577,335 (GRCm39) |
N53K |
possibly damaging |
Het |
| Nek11 |
C |
A |
9: 105,270,151 (GRCm39) |
A24S |
probably benign |
Het |
| Nudt19 |
G |
T |
7: 35,250,939 (GRCm39) |
P267T |
probably benign |
Het |
| Olfml2b |
T |
C |
1: 170,508,684 (GRCm39) |
M514T |
possibly damaging |
Het |
| Or14a258 |
A |
T |
7: 86,035,582 (GRCm39) |
C95* |
probably null |
Het |
| Or2ag17 |
C |
A |
7: 106,390,030 (GRCm39) |
M59I |
probably benign |
Het |
| Or52i2 |
A |
G |
7: 102,319,406 (GRCm39) |
D93G |
probably benign |
Het |
| Or6k4 |
A |
T |
1: 173,964,327 (GRCm39) |
T6S |
probably benign |
Het |
| P3h1 |
T |
A |
4: 119,095,149 (GRCm39) |
F302Y |
probably damaging |
Het |
| Pappa2 |
T |
A |
1: 158,592,671 (GRCm39) |
|
probably benign |
Het |
| Pex2 |
A |
C |
3: 5,626,424 (GRCm39) |
H128Q |
probably benign |
Het |
| Phf11d |
A |
C |
14: 59,590,180 (GRCm39) |
L214R |
probably damaging |
Het |
| Plcg2 |
G |
A |
8: 118,300,136 (GRCm39) |
|
probably benign |
Het |
| Ppargc1b |
A |
C |
18: 61,441,016 (GRCm39) |
L634R |
possibly damaging |
Het |
| Prune1 |
A |
T |
3: 95,169,671 (GRCm39) |
I177N |
probably damaging |
Het |
| Puf60 |
T |
C |
15: 75,942,334 (GRCm39) |
D496G |
probably damaging |
Het |
| Rasl11b |
A |
G |
5: 74,356,824 (GRCm39) |
|
probably null |
Het |
| Sdr42e1 |
A |
T |
8: 118,389,848 (GRCm39) |
F264L |
probably damaging |
Het |
| Sec24b |
A |
T |
3: 129,777,814 (GRCm39) |
|
probably null |
Het |
| Sgta |
G |
T |
10: 80,886,893 (GRCm39) |
P79T |
probably benign |
Het |
| Shisa9 |
C |
T |
16: 11,802,818 (GRCm39) |
T125M |
probably damaging |
Het |
| Shoc1 |
T |
A |
4: 59,066,534 (GRCm39) |
|
probably benign |
Het |
| Slc12a2 |
A |
G |
18: 58,063,283 (GRCm39) |
D921G |
probably damaging |
Het |
| Slc13a5 |
C |
T |
11: 72,136,059 (GRCm39) |
V494I |
probably benign |
Het |
| Slc13a5 |
T |
A |
11: 72,152,956 (GRCm39) |
I42L |
possibly damaging |
Het |
| Spire2 |
G |
A |
8: 124,089,750 (GRCm39) |
|
probably benign |
Het |
| Sptbn4 |
G |
A |
7: 27,104,336 (GRCm39) |
R962C |
probably benign |
Het |
| St8sia5 |
G |
A |
18: 77,342,420 (GRCm39) |
V377I |
probably benign |
Het |
| Stag2 |
T |
G |
X: 41,295,014 (GRCm39) |
|
probably benign |
Het |
| Syne1 |
C |
A |
10: 5,374,311 (GRCm39) |
M165I |
probably benign |
Het |
| Synm |
C |
A |
7: 67,384,672 (GRCm39) |
V997L |
probably damaging |
Het |
| Tacc1 |
A |
G |
8: 25,672,392 (GRCm39) |
S279P |
probably benign |
Het |
| Tbc1d10a |
T |
C |
11: 4,162,901 (GRCm39) |
|
probably null |
Het |
| Tbc1d19 |
A |
G |
5: 54,017,498 (GRCm39) |
T302A |
probably damaging |
Het |
| Tecpr1 |
A |
C |
5: 144,155,335 (GRCm39) |
N74K |
probably damaging |
Het |
| Tmem120a |
T |
C |
5: 135,771,252 (GRCm39) |
E28G |
possibly damaging |
Het |
| Tnfrsf1b |
A |
T |
4: 144,951,382 (GRCm39) |
I186N |
probably benign |
Het |
| Trim55 |
A |
G |
3: 19,716,025 (GRCm39) |
D195G |
probably benign |
Het |
| Trpm3 |
G |
T |
19: 22,692,720 (GRCm39) |
|
probably null |
Het |
| Ttc39a |
T |
A |
4: 109,301,376 (GRCm39) |
S571T |
probably benign |
Het |
| Vwf |
T |
G |
6: 125,620,260 (GRCm39) |
I1646S |
probably benign |
Het |
| Wbp2nl |
T |
C |
15: 82,198,483 (GRCm39) |
F340S |
possibly damaging |
Het |
| Yeats2 |
T |
C |
16: 19,971,719 (GRCm39) |
M1T |
probably null |
Het |
| Zfp236 |
T |
A |
18: 82,675,112 (GRCm39) |
E460V |
probably damaging |
Het |
| Zfp277 |
G |
A |
12: 40,428,876 (GRCm39) |
|
probably benign |
Het |
| Zfp975 |
T |
A |
7: 42,311,916 (GRCm39) |
K232N |
probably benign |
Het |
| Zxdc |
T |
C |
6: 90,349,519 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Fam186a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00588:Fam186a
|
APN |
15 |
99,825,572 (GRCm39) |
splice site |
probably benign |
|
|
IGL03047:Fam186a
|
UTSW |
15 |
99,843,589 (GRCm39) |
missense |
unknown |
|
|
R0172:Fam186a
|
UTSW |
15 |
99,852,768 (GRCm39) |
missense |
unknown |
|
|
R0381:Fam186a
|
UTSW |
15 |
99,840,055 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0799:Fam186a
|
UTSW |
15 |
99,839,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1295:Fam186a
|
UTSW |
15 |
99,837,670 (GRCm39) |
splice site |
probably benign |
|
|
R1366:Fam186a
|
UTSW |
15 |
99,841,270 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1519:Fam186a
|
UTSW |
15 |
99,845,536 (GRCm39) |
missense |
unknown |
|
|
R1592:Fam186a
|
UTSW |
15 |
99,838,199 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1636:Fam186a
|
UTSW |
15 |
99,839,539 (GRCm39) |
missense |
unknown |
|
|
R1719:Fam186a
|
UTSW |
15 |
99,840,227 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1759:Fam186a
|
UTSW |
15 |
99,864,762 (GRCm39) |
nonsense |
probably null |
|
|
R1856:Fam186a
|
UTSW |
15 |
99,838,183 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2131:Fam186a
|
UTSW |
15 |
99,831,557 (GRCm39) |
unclassified |
probably benign |
|
|
R2192:Fam186a
|
UTSW |
15 |
99,838,192 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2239:Fam186a
|
UTSW |
15 |
99,852,745 (GRCm39) |
missense |
unknown |
|
|
R2251:Fam186a
|
UTSW |
15 |
99,842,978 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2902:Fam186a
|
UTSW |
15 |
99,843,049 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3037:Fam186a
|
UTSW |
15 |
99,841,675 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3744:Fam186a
|
UTSW |
15 |
99,845,416 (GRCm39) |
missense |
unknown |
|
|
R4021:Fam186a
|
UTSW |
15 |
99,839,680 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4183:Fam186a
|
UTSW |
15 |
99,831,566 (GRCm39) |
unclassified |
probably benign |
|
|
R4238:Fam186a
|
UTSW |
15 |
99,841,523 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4667:Fam186a
|
UTSW |
15 |
99,842,413 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4817:Fam186a
|
UTSW |
15 |
99,831,419 (GRCm39) |
unclassified |
probably benign |
|
|
R4835:Fam186a
|
UTSW |
15 |
99,843,689 (GRCm39) |
missense |
unknown |
|
|
R4837:Fam186a
|
UTSW |
15 |
99,838,678 (GRCm39) |
missense |
unknown |
|
|
R4897:Fam186a
|
UTSW |
15 |
99,843,158 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4902:Fam186a
|
UTSW |
15 |
99,844,723 (GRCm39) |
missense |
unknown |
|
|
R4950:Fam186a
|
UTSW |
15 |
99,839,534 (GRCm39) |
missense |
unknown |
|
|
R4995:Fam186a
|
UTSW |
15 |
99,842,980 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5062:Fam186a
|
UTSW |
15 |
99,842,527 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5124:Fam186a
|
UTSW |
15 |
99,840,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5133:Fam186a
|
UTSW |
15 |
99,853,374 (GRCm39) |
missense |
unknown |
|
|
R5424:Fam186a
|
UTSW |
15 |
99,843,644 (GRCm39) |
missense |
unknown |
|
|
R5624:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5628:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5637:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5639:Fam186a
|
UTSW |
15 |
99,844,931 (GRCm39) |
missense |
unknown |
|
|
R5652:Fam186a
|
UTSW |
15 |
99,843,253 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5673:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5799:Fam186a
|
UTSW |
15 |
99,864,705 (GRCm39) |
nonsense |
probably null |
|
|
R5965:Fam186a
|
UTSW |
15 |
99,842,978 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6044:Fam186a
|
UTSW |
15 |
99,839,878 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6077:Fam186a
|
UTSW |
15 |
99,840,584 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6120:Fam186a
|
UTSW |
15 |
99,838,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6185:Fam186a
|
UTSW |
15 |
99,845,530 (GRCm39) |
missense |
unknown |
|
|
R6186:Fam186a
|
UTSW |
15 |
99,845,206 (GRCm39) |
missense |
unknown |
|
|
R6242:Fam186a
|
UTSW |
15 |
99,837,788 (GRCm39) |
missense |
unknown |
|
|
R6351:Fam186a
|
UTSW |
15 |
99,839,623 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6368:Fam186a
|
UTSW |
15 |
99,841,198 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6369:Fam186a
|
UTSW |
15 |
99,845,212 (GRCm39) |
missense |
unknown |
|
|
R6559:Fam186a
|
UTSW |
15 |
99,842,356 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6855:Fam186a
|
UTSW |
15 |
99,852,756 (GRCm39) |
missense |
unknown |
|
|
R6867:Fam186a
|
UTSW |
15 |
99,843,731 (GRCm39) |
missense |
unknown |
|
|
R6957:Fam186a
|
UTSW |
15 |
99,844,357 (GRCm39) |
missense |
unknown |
|
|
R6961:Fam186a
|
UTSW |
15 |
99,838,082 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6994:Fam186a
|
UTSW |
15 |
99,840,347 (GRCm39) |
missense |
probably benign |
0.35 |
|
R6996:Fam186a
|
UTSW |
15 |
99,853,374 (GRCm39) |
missense |
unknown |
|
|
R7062:Fam186a
|
UTSW |
15 |
99,831,521 (GRCm39) |
unclassified |
probably benign |
|
|
R7064:Fam186a
|
UTSW |
15 |
99,839,557 (GRCm39) |
missense |
unknown |
|
|
R7173:Fam186a
|
UTSW |
15 |
99,843,531 (GRCm39) |
missense |
unknown |
|
|
R7244:Fam186a
|
UTSW |
15 |
99,844,273 (GRCm39) |
missense |
unknown |
|
|
R7270:Fam186a
|
UTSW |
15 |
99,842,033 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7410:Fam186a
|
UTSW |
15 |
99,844,826 (GRCm39) |
nonsense |
probably null |
|
|
R7437:Fam186a
|
UTSW |
15 |
99,840,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7475:Fam186a
|
UTSW |
15 |
99,845,395 (GRCm39) |
missense |
unknown |
|
|
R7487:Fam186a
|
UTSW |
15 |
99,840,017 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7526:Fam186a
|
UTSW |
15 |
99,839,796 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7650:Fam186a
|
UTSW |
15 |
99,837,788 (GRCm39) |
missense |
unknown |
|
|
R7658:Fam186a
|
UTSW |
15 |
99,837,725 (GRCm39) |
missense |
unknown |
|
|
R7663:Fam186a
|
UTSW |
15 |
99,842,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7703:Fam186a
|
UTSW |
15 |
99,852,678 (GRCm39) |
missense |
unknown |
|
|
R7814:Fam186a
|
UTSW |
15 |
99,842,545 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7958:Fam186a
|
UTSW |
15 |
99,841,189 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7970:Fam186a
|
UTSW |
15 |
99,831,467 (GRCm39) |
missense |
unknown |
|
|
R8076:Fam186a
|
UTSW |
15 |
99,841,351 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8087:Fam186a
|
UTSW |
15 |
99,839,725 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8130:Fam186a
|
UTSW |
15 |
99,841,914 (GRCm39) |
frame shift |
probably null |
|
|
R8239:Fam186a
|
UTSW |
15 |
99,839,191 (GRCm39) |
missense |
unknown |
|
|
R8246:Fam186a
|
UTSW |
15 |
99,838,428 (GRCm39) |
missense |
unknown |
|
|
R8446:Fam186a
|
UTSW |
15 |
99,845,335 (GRCm39) |
missense |
unknown |
|
|
R8469:Fam186a
|
UTSW |
15 |
99,845,186 (GRCm39) |
missense |
unknown |
|
|
R8676:Fam186a
|
UTSW |
15 |
99,845,023 (GRCm39) |
missense |
unknown |
|
|
R8790:Fam186a
|
UTSW |
15 |
99,841,024 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8808:Fam186a
|
UTSW |
15 |
99,842,604 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8848:Fam186a
|
UTSW |
15 |
99,838,034 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9083:Fam186a
|
UTSW |
15 |
99,843,079 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9106:Fam186a
|
UTSW |
15 |
99,844,107 (GRCm39) |
small deletion |
probably benign |
|
|
R9116:Fam186a
|
UTSW |
15 |
99,840,472 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9156:Fam186a
|
UTSW |
15 |
99,841,159 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R9227:Fam186a
|
UTSW |
15 |
99,853,384 (GRCm39) |
missense |
unknown |
|
|
R9250:Fam186a
|
UTSW |
15 |
99,845,330 (GRCm39) |
missense |
unknown |
|
|
R9282:Fam186a
|
UTSW |
15 |
99,839,879 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9495:Fam186a
|
UTSW |
15 |
99,844,766 (GRCm39) |
missense |
unknown |
|
|
R9514:Fam186a
|
UTSW |
15 |
99,844,766 (GRCm39) |
missense |
unknown |
|
|
R9521:Fam186a
|
UTSW |
15 |
99,841,471 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9553:Fam186a
|
UTSW |
15 |
99,844,561 (GRCm39) |
missense |
unknown |
|
|
R9641:Fam186a
|
UTSW |
15 |
99,838,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9655:Fam186a
|
UTSW |
15 |
99,840,973 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9661:Fam186a
|
UTSW |
15 |
99,842,492 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9673:Fam186a
|
UTSW |
15 |
99,841,024 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9762:Fam186a
|
UTSW |
15 |
99,842,393 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
X0021:Fam186a
|
UTSW |
15 |
99,843,316 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Fam186a
|
UTSW |
15 |
99,843,875 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGACTTCTCTGGGCTTCAAGTTGC -3'
(R):5'- TGAGGACCAGTTTCCCCACTAAGG -3'
Sequencing Primer
(F):5'- TGCTTCTTAGAAAGATGGCTCC -3'
(R):5'- GGTAATGAAGATTTGCCTCACCC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation