Incidental Mutation 'R2145:Cntn5'
| ID |
233740 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cntn5
|
| Ensembl Gene |
ENSMUSG00000039488 |
| Gene Name |
contactin 5 |
| Synonyms |
A830025P08Rik, 6720426O10Rik, NB-2, LOC244683 |
| MMRRC Submission |
040148-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2145 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
9660896-10904780 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 9748420 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Glutamine
at position 487
(P487Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135903
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074133]
[ENSMUST00000160216]
[ENSMUST00000162484]
[ENSMUST00000179049]
|
| AlphaFold |
P68500 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000074133
AA Change: P692Q
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000073769
Gene: ENSMUSG00000039488
AA Change: P692Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
IGc2
|
113 |
179 |
1.11e-10 |
SMART |
|
IG
|
201 |
289 |
4.82e-6 |
SMART |
|
IGc2
|
312 |
375 |
1.4e-16 |
SMART |
|
IGc2
|
401 |
464 |
8.97e-15 |
SMART |
|
IGc2
|
493 |
557 |
4.96e-8 |
SMART |
|
IG
|
577 |
667 |
2.13e-7 |
SMART |
|
FN3
|
670 |
756 |
1.01e-11 |
SMART |
|
FN3
|
773 |
859 |
9.19e-1 |
SMART |
|
FN3
|
875 |
958 |
3.99e-10 |
SMART |
|
FN3
|
974 |
1053 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000160216
AA Change: P692Q
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000124327
Gene: ENSMUSG00000039488
AA Change: P692Q
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
IGc2
|
113 |
179 |
1.11e-10 |
SMART |
|
IG
|
201 |
289 |
4.82e-6 |
SMART |
|
IGc2
|
312 |
375 |
1.4e-16 |
SMART |
|
IGc2
|
401 |
464 |
8.97e-15 |
SMART |
|
IGc2
|
493 |
557 |
4.96e-8 |
SMART |
|
IG
|
577 |
667 |
2.13e-7 |
SMART |
|
FN3
|
670 |
756 |
1.01e-11 |
SMART |
|
FN3
|
773 |
859 |
9.19e-1 |
SMART |
|
FN3
|
875 |
958 |
3.99e-10 |
SMART |
|
FN3
|
974 |
1053 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162484
AA Change: P487Q
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000124214
Gene: ENSMUSG00000039488
AA Change: P487Q
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
10 |
84 |
1.12e2 |
SMART |
|
IGc2
|
107 |
170 |
1.4e-16 |
SMART |
|
IGc2
|
196 |
259 |
8.97e-15 |
SMART |
|
IGc2
|
288 |
352 |
4.96e-8 |
SMART |
|
IG
|
372 |
462 |
2.13e-7 |
SMART |
|
FN3
|
465 |
551 |
1.01e-11 |
SMART |
|
FN3
|
568 |
654 |
9.19e-1 |
SMART |
|
FN3
|
670 |
753 |
3.99e-10 |
SMART |
|
FN3
|
769 |
848 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000179049
AA Change: P487Q
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000135903
Gene: ENSMUSG00000039488
AA Change: P487Q
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
10 |
84 |
1.12e2 |
SMART |
|
IGc2
|
107 |
170 |
1.4e-16 |
SMART |
|
IGc2
|
196 |
259 |
8.97e-15 |
SMART |
|
IGc2
|
288 |
352 |
4.96e-8 |
SMART |
|
IG
|
372 |
462 |
2.13e-7 |
SMART |
|
FN3
|
465 |
551 |
1.01e-11 |
SMART |
|
FN3
|
568 |
654 |
9.19e-1 |
SMART |
|
FN3
|
670 |
753 |
3.99e-10 |
SMART |
|
FN3
|
769 |
848 |
1.68e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.1562 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.6%
|
| Validation Efficiency |
97% (101/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
PHENOTYPE: Homozygous null mice are viable, fertile, and less susceptible to audiogenic seizures. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
A |
G |
7: 119,953,701 (GRCm39) |
N535S |
probably benign |
Het |
| Abcc6 |
A |
T |
7: 45,648,165 (GRCm39) |
L717Q |
probably benign |
Het |
| Abraxas2 |
C |
A |
7: 132,484,790 (GRCm39) |
Q278K |
probably benign |
Het |
| Acap2 |
A |
T |
16: 30,924,342 (GRCm39) |
D637E |
probably benign |
Het |
| AI661453 |
A |
G |
17: 47,777,023 (GRCm39) |
|
probably benign |
Het |
| Aoah |
A |
T |
13: 21,024,266 (GRCm39) |
E74V |
probably damaging |
Het |
| Aoc1l1 |
A |
T |
6: 48,953,629 (GRCm39) |
D518V |
probably damaging |
Het |
| Appl1 |
A |
G |
14: 26,671,576 (GRCm39) |
L292S |
possibly damaging |
Het |
| Astl |
T |
A |
2: 127,189,109 (GRCm39) |
V166E |
probably damaging |
Het |
| Bbs1 |
T |
G |
19: 4,953,735 (GRCm39) |
K143Q |
possibly damaging |
Het |
| Bbx |
T |
C |
16: 50,094,907 (GRCm39) |
|
probably benign |
Het |
| Birc6 |
A |
T |
17: 74,967,408 (GRCm39) |
Q4103L |
possibly damaging |
Het |
| C1qtnf2 |
T |
G |
11: 43,381,811 (GRCm39) |
F178V |
probably damaging |
Het |
| Camta2 |
A |
G |
11: 70,562,401 (GRCm39) |
F999L |
probably benign |
Het |
| Cfap68 |
T |
C |
9: 50,676,174 (GRCm39) |
Y32C |
probably damaging |
Het |
| Clcn7 |
A |
G |
17: 25,363,425 (GRCm39) |
I34V |
probably benign |
Het |
| Ctu2 |
T |
A |
8: 123,205,891 (GRCm39) |
I213K |
probably benign |
Het |
| Des |
C |
A |
1: 75,340,108 (GRCm39) |
|
probably benign |
Het |
| Dgcr8 |
A |
T |
16: 18,098,094 (GRCm39) |
D432E |
probably benign |
Het |
| Dlgap5 |
G |
A |
14: 47,633,380 (GRCm39) |
R549* |
probably null |
Het |
| Dmac2l |
A |
G |
12: 69,787,828 (GRCm39) |
Q88R |
probably damaging |
Het |
| Dmxl2 |
T |
C |
9: 54,323,194 (GRCm39) |
T1397A |
probably damaging |
Het |
| Dnmt1 |
T |
A |
9: 20,848,451 (GRCm39) |
|
probably benign |
Het |
| Dstyk |
T |
A |
1: 132,391,113 (GRCm39) |
M838K |
probably damaging |
Het |
| Dtwd1 |
C |
A |
2: 126,001,904 (GRCm39) |
T208N |
probably damaging |
Het |
| Dvl1 |
G |
A |
4: 155,932,273 (GRCm39) |
V28I |
possibly damaging |
Het |
| Dync1i2 |
T |
A |
2: 71,044,907 (GRCm39) |
|
probably benign |
Het |
| Fer1l6 |
T |
A |
15: 58,499,383 (GRCm39) |
M1251K |
probably benign |
Het |
| Fmod |
T |
C |
1: 133,968,256 (GRCm39) |
Y99H |
probably benign |
Het |
| Fn1 |
A |
T |
1: 71,645,163 (GRCm39) |
V1552D |
probably damaging |
Het |
| Fnip2 |
A |
T |
3: 79,407,739 (GRCm39) |
S281T |
probably damaging |
Het |
| Glb1 |
A |
G |
9: 114,293,233 (GRCm39) |
H536R |
probably benign |
Het |
| Glis2 |
T |
A |
16: 4,431,506 (GRCm39) |
S344R |
possibly damaging |
Het |
| Gm4847 |
A |
T |
1: 166,462,472 (GRCm39) |
S339R |
probably benign |
Het |
| Gpr155 |
A |
G |
2: 73,187,002 (GRCm39) |
S44P |
probably benign |
Het |
| Gprin1 |
G |
A |
13: 54,886,445 (GRCm39) |
P610S |
probably damaging |
Het |
| Gvin3 |
T |
A |
7: 106,202,215 (GRCm39) |
H343L |
possibly damaging |
Het |
| H2-Ob |
A |
T |
17: 34,461,554 (GRCm39) |
M98L |
probably benign |
Het |
| H3c6 |
T |
C |
13: 23,746,530 (GRCm39) |
T4A |
probably benign |
Het |
| Hmcn2 |
T |
C |
2: 31,223,943 (GRCm39) |
|
probably benign |
Het |
| Ikbke |
C |
A |
1: 131,201,211 (GRCm39) |
V176L |
probably damaging |
Het |
| Il13 |
T |
C |
11: 53,523,351 (GRCm39) |
T85A |
possibly damaging |
Het |
| Inpp5k |
A |
T |
11: 75,538,017 (GRCm39) |
|
probably null |
Het |
| Irgm2 |
T |
C |
11: 58,111,355 (GRCm39) |
S361P |
possibly damaging |
Het |
| Itga11 |
C |
T |
9: 62,639,486 (GRCm39) |
|
probably benign |
Het |
| Kalrn |
G |
T |
16: 33,829,632 (GRCm39) |
|
probably benign |
Het |
| Kcng1 |
C |
A |
2: 168,110,952 (GRCm39) |
G71C |
probably damaging |
Het |
| Kcnq5 |
T |
A |
1: 21,575,573 (GRCm39) |
D291V |
probably damaging |
Het |
| Klhl7 |
A |
T |
5: 24,305,861 (GRCm39) |
M37L |
probably benign |
Het |
| Letm1 |
A |
AG |
5: 33,926,859 (GRCm39) |
|
probably null |
Het |
| Lhx6 |
C |
T |
2: 35,977,478 (GRCm39) |
V325I |
probably benign |
Het |
| Lipc |
A |
G |
9: 70,841,817 (GRCm39) |
I9T |
possibly damaging |
Het |
| Lsmem1 |
GTACATACATACATACATACATACATACA |
GTACATACATACATACATACATACATACATACA |
12: 40,235,260 (GRCm39) |
|
probably null |
Het |
| Mast1 |
C |
A |
8: 85,648,107 (GRCm39) |
G458V |
probably damaging |
Het |
| Mga |
T |
C |
2: 119,794,638 (GRCm39) |
V2565A |
possibly damaging |
Het |
| Mpzl2 |
C |
G |
9: 44,955,471 (GRCm39) |
D127E |
probably benign |
Het |
| Mrtfb |
T |
C |
16: 13,230,450 (GRCm39) |
I1045T |
probably damaging |
Het |
| Myh3 |
T |
A |
11: 66,981,882 (GRCm39) |
C793S |
probably benign |
Het |
| Nomo1 |
T |
C |
7: 45,715,928 (GRCm39) |
L765P |
probably damaging |
Het |
| Nup210 |
A |
G |
6: 91,005,858 (GRCm39) |
I1335T |
possibly damaging |
Het |
| Or52b3 |
T |
C |
7: 102,204,267 (GRCm39) |
|
probably null |
Het |
| Oxr1 |
T |
A |
15: 41,683,340 (GRCm39) |
S254R |
probably damaging |
Het |
| Pan3 |
A |
G |
5: 147,466,908 (GRCm39) |
I592V |
possibly damaging |
Het |
| Pask |
C |
T |
1: 93,249,019 (GRCm39) |
A794T |
probably benign |
Het |
| Pex2 |
T |
C |
3: 5,626,650 (GRCm39) |
E53G |
probably damaging |
Het |
| Pfkfb2 |
T |
C |
1: 130,626,460 (GRCm39) |
T438A |
probably benign |
Het |
| Phactr4 |
T |
C |
4: 132,098,095 (GRCm39) |
E391G |
probably damaging |
Het |
| Pira2 |
A |
T |
7: 3,847,344 (GRCm39) |
L115Q |
probably damaging |
Het |
| Pkhd1l1 |
A |
T |
15: 44,376,273 (GRCm39) |
|
probably null |
Het |
| Pnlip |
A |
G |
19: 58,664,876 (GRCm39) |
S235G |
probably benign |
Het |
| Prkd1 |
A |
G |
12: 50,536,694 (GRCm39) |
V130A |
possibly damaging |
Het |
| Ptpn13 |
A |
G |
5: 103,703,999 (GRCm39) |
T1344A |
probably benign |
Het |
| Ptprc |
T |
C |
1: 138,001,419 (GRCm39) |
Y780C |
probably damaging |
Het |
| Pxn |
T |
A |
5: 115,690,815 (GRCm39) |
|
probably benign |
Het |
| Rap1gap2 |
G |
A |
11: 74,316,802 (GRCm39) |
T245M |
probably damaging |
Het |
| Rc3h1 |
G |
T |
1: 160,757,827 (GRCm39) |
K48N |
probably damaging |
Het |
| Rfwd3 |
T |
C |
8: 112,009,245 (GRCm39) |
I444V |
probably benign |
Het |
| Rictor |
C |
T |
15: 6,794,588 (GRCm39) |
R293C |
probably damaging |
Het |
| Rif1 |
T |
A |
2: 52,001,412 (GRCm39) |
I1622N |
possibly damaging |
Het |
| Rnf213 |
T |
C |
11: 119,306,019 (GRCm39) |
V609A |
probably benign |
Het |
| Scgb1b2 |
G |
T |
7: 30,991,188 (GRCm39) |
|
probably benign |
Het |
| Serac1 |
A |
T |
17: 6,101,060 (GRCm39) |
I448N |
probably damaging |
Het |
| Sh3kbp1 |
C |
A |
X: 158,607,492 (GRCm39) |
T200K |
probably benign |
Het |
| Sned1 |
T |
A |
1: 93,199,406 (GRCm39) |
F495L |
probably damaging |
Het |
| Socs7 |
T |
C |
11: 97,263,950 (GRCm39) |
F281L |
probably benign |
Het |
| Spta1 |
C |
T |
1: 174,040,180 (GRCm39) |
L1214F |
probably benign |
Het |
| Ssu72 |
A |
G |
4: 155,789,900 (GRCm39) |
E21G |
probably damaging |
Het |
| Syngr4 |
A |
G |
7: 45,536,464 (GRCm39) |
V186A |
probably benign |
Het |
| Tars3 |
G |
A |
7: 65,305,539 (GRCm39) |
M254I |
possibly damaging |
Het |
| Tmem130 |
C |
A |
5: 144,680,595 (GRCm39) |
V270L |
probably benign |
Het |
| Trim66 |
A |
T |
7: 109,074,320 (GRCm39) |
I647N |
probably damaging |
Het |
| Tspyl2 |
A |
T |
X: 151,121,890 (GRCm39) |
D572E |
probably benign |
Het |
| Unc45b |
G |
A |
11: 82,808,580 (GRCm39) |
R222H |
probably benign |
Het |
| Uxs1 |
T |
C |
1: 43,866,783 (GRCm39) |
Y29C |
probably damaging |
Het |
| Virma |
T |
A |
4: 11,548,726 (GRCm39) |
|
probably benign |
Het |
| Vmn1r202 |
C |
T |
13: 22,685,953 (GRCm39) |
G155S |
possibly damaging |
Het |
| Vmn2r24 |
T |
A |
6: 123,755,972 (GRCm39) |
F15I |
probably benign |
Het |
| Wdr64 |
A |
G |
1: 175,594,661 (GRCm39) |
T471A |
probably benign |
Het |
| Zfa-ps |
T |
A |
10: 52,419,373 (GRCm39) |
|
noncoding transcript |
Het |
| Zfp260 |
A |
G |
7: 29,804,765 (GRCm39) |
K222E |
probably damaging |
Het |
| Zfp300 |
A |
G |
X: 20,948,190 (GRCm39) |
S525P |
possibly damaging |
Het |
| Zfp821 |
A |
G |
8: 110,450,979 (GRCm39) |
D324G |
probably damaging |
Het |
| Zfp934 |
T |
C |
13: 62,665,648 (GRCm39) |
D331G |
probably damaging |
Het |
| Zscan29 |
T |
C |
2: 121,000,587 (GRCm39) |
R7G |
probably damaging |
Het |
|
| Other mutations in Cntn5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00742:Cntn5
|
APN |
9 |
9,976,302 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01118:Cntn5
|
APN |
9 |
9,831,565 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01328:Cntn5
|
APN |
9 |
9,781,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01445:Cntn5
|
APN |
9 |
9,693,489 (GRCm39) |
splice site |
probably benign |
|
|
IGL01505:Cntn5
|
APN |
9 |
9,706,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01556:Cntn5
|
APN |
9 |
9,673,913 (GRCm39) |
missense |
probably benign |
|
|
IGL01804:Cntn5
|
APN |
9 |
9,831,542 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02173:Cntn5
|
APN |
9 |
9,748,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02250:Cntn5
|
APN |
9 |
10,145,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02366:Cntn5
|
APN |
9 |
9,984,060 (GRCm39) |
splice site |
probably benign |
|
|
IGL02565:Cntn5
|
APN |
9 |
10,145,343 (GRCm39) |
nonsense |
probably null |
|
|
IGL02593:Cntn5
|
APN |
9 |
9,833,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02743:Cntn5
|
APN |
9 |
9,984,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02976:Cntn5
|
APN |
9 |
10,419,104 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03103:Cntn5
|
APN |
9 |
9,972,817 (GRCm39) |
splice site |
probably benign |
|
|
IGL03114:Cntn5
|
APN |
9 |
9,748,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03156:Cntn5
|
APN |
9 |
9,673,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Cntn5
|
UTSW |
9 |
10,048,683 (GRCm39) |
splice site |
probably null |
|
|
R0243:Cntn5
|
UTSW |
9 |
9,781,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0385:Cntn5
|
UTSW |
9 |
9,972,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0541:Cntn5
|
UTSW |
9 |
9,673,407 (GRCm39) |
splice site |
probably benign |
|
|
R0827:Cntn5
|
UTSW |
9 |
9,666,943 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1029:Cntn5
|
UTSW |
9 |
9,831,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1440:Cntn5
|
UTSW |
9 |
10,145,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Cntn5
|
UTSW |
9 |
9,673,801 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1536:Cntn5
|
UTSW |
9 |
9,976,321 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1746:Cntn5
|
UTSW |
9 |
9,831,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1761:Cntn5
|
UTSW |
9 |
10,172,059 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1764:Cntn5
|
UTSW |
9 |
9,673,988 (GRCm39) |
missense |
probably benign |
|
|
R1859:Cntn5
|
UTSW |
9 |
9,972,839 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Cntn5
|
UTSW |
9 |
9,984,082 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1888:Cntn5
|
UTSW |
9 |
9,984,082 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1950:Cntn5
|
UTSW |
9 |
9,781,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Cntn5
|
UTSW |
9 |
9,748,420 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2437:Cntn5
|
UTSW |
9 |
10,048,758 (GRCm39) |
nonsense |
probably null |
|
|
R2440:Cntn5
|
UTSW |
9 |
10,171,960 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2504:Cntn5
|
UTSW |
9 |
10,172,126 (GRCm39) |
missense |
probably benign |
|
|
R3054:Cntn5
|
UTSW |
9 |
10,419,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R3056:Cntn5
|
UTSW |
9 |
10,419,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R3804:Cntn5
|
UTSW |
9 |
9,781,668 (GRCm39) |
splice site |
probably benign |
|
|
R4164:Cntn5
|
UTSW |
9 |
9,781,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4444:Cntn5
|
UTSW |
9 |
9,704,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4472:Cntn5
|
UTSW |
9 |
10,048,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Cntn5
|
UTSW |
9 |
9,673,297 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4624:Cntn5
|
UTSW |
9 |
9,704,809 (GRCm39) |
nonsense |
probably null |
|
|
R4652:Cntn5
|
UTSW |
9 |
9,704,917 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4664:Cntn5
|
UTSW |
9 |
10,144,214 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4679:Cntn5
|
UTSW |
9 |
9,970,536 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4829:Cntn5
|
UTSW |
9 |
9,976,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4929:Cntn5
|
UTSW |
9 |
9,976,400 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5211:Cntn5
|
UTSW |
9 |
9,704,894 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5406:Cntn5
|
UTSW |
9 |
9,833,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5468:Cntn5
|
UTSW |
9 |
9,743,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5584:Cntn5
|
UTSW |
9 |
9,661,457 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5688:Cntn5
|
UTSW |
9 |
9,748,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5762:Cntn5
|
UTSW |
9 |
9,748,394 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6141:Cntn5
|
UTSW |
9 |
10,144,162 (GRCm39) |
missense |
probably benign |
|
|
R6147:Cntn5
|
UTSW |
9 |
10,012,894 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6325:Cntn5
|
UTSW |
9 |
10,144,328 (GRCm39) |
splice site |
probably null |
|
|
R6377:Cntn5
|
UTSW |
9 |
9,743,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6774:Cntn5
|
UTSW |
9 |
10,144,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Cntn5
|
UTSW |
9 |
10,904,704 (GRCm39) |
start gained |
probably benign |
|
|
R7252:Cntn5
|
UTSW |
9 |
9,831,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7363:Cntn5
|
UTSW |
9 |
10,172,021 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7401:Cntn5
|
UTSW |
9 |
9,833,466 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7488:Cntn5
|
UTSW |
9 |
9,970,570 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7548:Cntn5
|
UTSW |
9 |
9,673,415 (GRCm39) |
splice site |
probably null |
|
|
R7662:Cntn5
|
UTSW |
9 |
9,661,390 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7718:Cntn5
|
UTSW |
9 |
9,984,133 (GRCm39) |
missense |
probably benign |
|
|
R7719:Cntn5
|
UTSW |
9 |
9,704,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7788:Cntn5
|
UTSW |
9 |
9,704,934 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7864:Cntn5
|
UTSW |
9 |
9,984,182 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7937:Cntn5
|
UTSW |
9 |
9,748,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8117:Cntn5
|
UTSW |
9 |
9,673,955 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8159:Cntn5
|
UTSW |
9 |
10,145,386 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8349:Cntn5
|
UTSW |
9 |
9,666,840 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8449:Cntn5
|
UTSW |
9 |
9,666,840 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8779:Cntn5
|
UTSW |
9 |
10,171,920 (GRCm39) |
missense |
probably benign |
|
|
R8789:Cntn5
|
UTSW |
9 |
9,673,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8985:Cntn5
|
UTSW |
9 |
10,171,960 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9370:Cntn5
|
UTSW |
9 |
9,833,520 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9382:Cntn5
|
UTSW |
9 |
9,673,817 (GRCm39) |
missense |
probably benign |
|
|
R9781:Cntn5
|
UTSW |
9 |
10,048,686 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Cntn5
|
UTSW |
9 |
10,090,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cntn5
|
UTSW |
9 |
9,673,967 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGGAAGTAGTTGACCATGATCAATG -3'
(R):5'- GTTTAGGCAAACACATCATCTCATG -3'
Sequencing Primer
(F):5'- GTTGACCATGATCAATGTTGTAAAG -3'
(R):5'- CATCATCTCATGAGATCCACATTGG -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation