Incidental Mutation 'R2145:Rictor'
| ID |
233771 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rictor
|
| Ensembl Gene |
ENSMUSG00000050310 |
| Gene Name |
RPTOR independent companion of MTOR, complex 2 |
| Synonyms |
D530039E11Rik, 4921505C17Rik, 6030405M08Rik |
| MMRRC Submission |
040148-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R2145 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
6737860-6829882 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 6794588 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Cysteine
at position 293
(R293C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051809
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061656]
|
| AlphaFold |
Q6QI06 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000061656
AA Change: R293C
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000051809
Gene: ENSMUSG00000050310
AA Change: R293C
| Domain | Start | End | E-Value | Type |
|---|
|
RICTOR_N
|
57 |
439 |
4.02e-185 |
SMART |
|
RICTOR_M
|
523 |
742 |
5.66e-98 |
SMART |
|
RasGEF_N_2
|
743 |
857 |
1.26e-54 |
SMART |
|
RICTOR_V
|
920 |
992 |
1.44e-40 |
SMART |
|
low complexity region
|
1019 |
1043 |
N/A |
INTRINSIC |
|
RICTOR_phospho
|
1084 |
1189 |
4.06e-58 |
SMART |
|
low complexity region
|
1221 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1255 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1273 |
1287 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1414 |
N/A |
INTRINSIC |
|
low complexity region
|
1464 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1628 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226181
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228266
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228918
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.6%
|
| Validation Efficiency |
97% (101/104) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal placental morphology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
A |
G |
7: 119,953,701 (GRCm39) |
N535S |
probably benign |
Het |
| Abcc6 |
A |
T |
7: 45,648,165 (GRCm39) |
L717Q |
probably benign |
Het |
| Abraxas2 |
C |
A |
7: 132,484,790 (GRCm39) |
Q278K |
probably benign |
Het |
| Acap2 |
A |
T |
16: 30,924,342 (GRCm39) |
D637E |
probably benign |
Het |
| AI661453 |
A |
G |
17: 47,777,023 (GRCm39) |
|
probably benign |
Het |
| Aoah |
A |
T |
13: 21,024,266 (GRCm39) |
E74V |
probably damaging |
Het |
| Aoc1l1 |
A |
T |
6: 48,953,629 (GRCm39) |
D518V |
probably damaging |
Het |
| Appl1 |
A |
G |
14: 26,671,576 (GRCm39) |
L292S |
possibly damaging |
Het |
| Astl |
T |
A |
2: 127,189,109 (GRCm39) |
V166E |
probably damaging |
Het |
| Bbs1 |
T |
G |
19: 4,953,735 (GRCm39) |
K143Q |
possibly damaging |
Het |
| Bbx |
T |
C |
16: 50,094,907 (GRCm39) |
|
probably benign |
Het |
| Birc6 |
A |
T |
17: 74,967,408 (GRCm39) |
Q4103L |
possibly damaging |
Het |
| C1qtnf2 |
T |
G |
11: 43,381,811 (GRCm39) |
F178V |
probably damaging |
Het |
| Camta2 |
A |
G |
11: 70,562,401 (GRCm39) |
F999L |
probably benign |
Het |
| Cfap68 |
T |
C |
9: 50,676,174 (GRCm39) |
Y32C |
probably damaging |
Het |
| Clcn7 |
A |
G |
17: 25,363,425 (GRCm39) |
I34V |
probably benign |
Het |
| Cntn5 |
G |
T |
9: 9,748,420 (GRCm39) |
P487Q |
probably damaging |
Het |
| Ctu2 |
T |
A |
8: 123,205,891 (GRCm39) |
I213K |
probably benign |
Het |
| Des |
C |
A |
1: 75,340,108 (GRCm39) |
|
probably benign |
Het |
| Dgcr8 |
A |
T |
16: 18,098,094 (GRCm39) |
D432E |
probably benign |
Het |
| Dlgap5 |
G |
A |
14: 47,633,380 (GRCm39) |
R549* |
probably null |
Het |
| Dmac2l |
A |
G |
12: 69,787,828 (GRCm39) |
Q88R |
probably damaging |
Het |
| Dmxl2 |
T |
C |
9: 54,323,194 (GRCm39) |
T1397A |
probably damaging |
Het |
| Dnmt1 |
T |
A |
9: 20,848,451 (GRCm39) |
|
probably benign |
Het |
| Dstyk |
T |
A |
1: 132,391,113 (GRCm39) |
M838K |
probably damaging |
Het |
| Dtwd1 |
C |
A |
2: 126,001,904 (GRCm39) |
T208N |
probably damaging |
Het |
| Dvl1 |
G |
A |
4: 155,932,273 (GRCm39) |
V28I |
possibly damaging |
Het |
| Dync1i2 |
T |
A |
2: 71,044,907 (GRCm39) |
|
probably benign |
Het |
| Fer1l6 |
T |
A |
15: 58,499,383 (GRCm39) |
M1251K |
probably benign |
Het |
| Fmod |
T |
C |
1: 133,968,256 (GRCm39) |
Y99H |
probably benign |
Het |
| Fn1 |
A |
T |
1: 71,645,163 (GRCm39) |
V1552D |
probably damaging |
Het |
| Fnip2 |
A |
T |
3: 79,407,739 (GRCm39) |
S281T |
probably damaging |
Het |
| Glb1 |
A |
G |
9: 114,293,233 (GRCm39) |
H536R |
probably benign |
Het |
| Glis2 |
T |
A |
16: 4,431,506 (GRCm39) |
S344R |
possibly damaging |
Het |
| Gm4847 |
A |
T |
1: 166,462,472 (GRCm39) |
S339R |
probably benign |
Het |
| Gpr155 |
A |
G |
2: 73,187,002 (GRCm39) |
S44P |
probably benign |
Het |
| Gprin1 |
G |
A |
13: 54,886,445 (GRCm39) |
P610S |
probably damaging |
Het |
| Gvin3 |
T |
A |
7: 106,202,215 (GRCm39) |
H343L |
possibly damaging |
Het |
| H2-Ob |
A |
T |
17: 34,461,554 (GRCm39) |
M98L |
probably benign |
Het |
| H3c6 |
T |
C |
13: 23,746,530 (GRCm39) |
T4A |
probably benign |
Het |
| Hmcn2 |
T |
C |
2: 31,223,943 (GRCm39) |
|
probably benign |
Het |
| Ikbke |
C |
A |
1: 131,201,211 (GRCm39) |
V176L |
probably damaging |
Het |
| Il13 |
T |
C |
11: 53,523,351 (GRCm39) |
T85A |
possibly damaging |
Het |
| Inpp5k |
A |
T |
11: 75,538,017 (GRCm39) |
|
probably null |
Het |
| Irgm2 |
T |
C |
11: 58,111,355 (GRCm39) |
S361P |
possibly damaging |
Het |
| Itga11 |
C |
T |
9: 62,639,486 (GRCm39) |
|
probably benign |
Het |
| Kalrn |
G |
T |
16: 33,829,632 (GRCm39) |
|
probably benign |
Het |
| Kcng1 |
C |
A |
2: 168,110,952 (GRCm39) |
G71C |
probably damaging |
Het |
| Kcnq5 |
T |
A |
1: 21,575,573 (GRCm39) |
D291V |
probably damaging |
Het |
| Klhl7 |
A |
T |
5: 24,305,861 (GRCm39) |
M37L |
probably benign |
Het |
| Letm1 |
A |
AG |
5: 33,926,859 (GRCm39) |
|
probably null |
Het |
| Lhx6 |
C |
T |
2: 35,977,478 (GRCm39) |
V325I |
probably benign |
Het |
| Lipc |
A |
G |
9: 70,841,817 (GRCm39) |
I9T |
possibly damaging |
Het |
| Lsmem1 |
GTACATACATACATACATACATACATACA |
GTACATACATACATACATACATACATACATACA |
12: 40,235,260 (GRCm39) |
|
probably null |
Het |
| Mast1 |
C |
A |
8: 85,648,107 (GRCm39) |
G458V |
probably damaging |
Het |
| Mga |
T |
C |
2: 119,794,638 (GRCm39) |
V2565A |
possibly damaging |
Het |
| Mpzl2 |
C |
G |
9: 44,955,471 (GRCm39) |
D127E |
probably benign |
Het |
| Mrtfb |
T |
C |
16: 13,230,450 (GRCm39) |
I1045T |
probably damaging |
Het |
| Myh3 |
T |
A |
11: 66,981,882 (GRCm39) |
C793S |
probably benign |
Het |
| Nomo1 |
T |
C |
7: 45,715,928 (GRCm39) |
L765P |
probably damaging |
Het |
| Nup210 |
A |
G |
6: 91,005,858 (GRCm39) |
I1335T |
possibly damaging |
Het |
| Or52b3 |
T |
C |
7: 102,204,267 (GRCm39) |
|
probably null |
Het |
| Oxr1 |
T |
A |
15: 41,683,340 (GRCm39) |
S254R |
probably damaging |
Het |
| Pan3 |
A |
G |
5: 147,466,908 (GRCm39) |
I592V |
possibly damaging |
Het |
| Pask |
C |
T |
1: 93,249,019 (GRCm39) |
A794T |
probably benign |
Het |
| Pex2 |
T |
C |
3: 5,626,650 (GRCm39) |
E53G |
probably damaging |
Het |
| Pfkfb2 |
T |
C |
1: 130,626,460 (GRCm39) |
T438A |
probably benign |
Het |
| Phactr4 |
T |
C |
4: 132,098,095 (GRCm39) |
E391G |
probably damaging |
Het |
| Pira2 |
A |
T |
7: 3,847,344 (GRCm39) |
L115Q |
probably damaging |
Het |
| Pkhd1l1 |
A |
T |
15: 44,376,273 (GRCm39) |
|
probably null |
Het |
| Pnlip |
A |
G |
19: 58,664,876 (GRCm39) |
S235G |
probably benign |
Het |
| Prkd1 |
A |
G |
12: 50,536,694 (GRCm39) |
V130A |
possibly damaging |
Het |
| Ptpn13 |
A |
G |
5: 103,703,999 (GRCm39) |
T1344A |
probably benign |
Het |
| Ptprc |
T |
C |
1: 138,001,419 (GRCm39) |
Y780C |
probably damaging |
Het |
| Pxn |
T |
A |
5: 115,690,815 (GRCm39) |
|
probably benign |
Het |
| Rap1gap2 |
G |
A |
11: 74,316,802 (GRCm39) |
T245M |
probably damaging |
Het |
| Rc3h1 |
G |
T |
1: 160,757,827 (GRCm39) |
K48N |
probably damaging |
Het |
| Rfwd3 |
T |
C |
8: 112,009,245 (GRCm39) |
I444V |
probably benign |
Het |
| Rif1 |
T |
A |
2: 52,001,412 (GRCm39) |
I1622N |
possibly damaging |
Het |
| Rnf213 |
T |
C |
11: 119,306,019 (GRCm39) |
V609A |
probably benign |
Het |
| Scgb1b2 |
G |
T |
7: 30,991,188 (GRCm39) |
|
probably benign |
Het |
| Serac1 |
A |
T |
17: 6,101,060 (GRCm39) |
I448N |
probably damaging |
Het |
| Sh3kbp1 |
C |
A |
X: 158,607,492 (GRCm39) |
T200K |
probably benign |
Het |
| Sned1 |
T |
A |
1: 93,199,406 (GRCm39) |
F495L |
probably damaging |
Het |
| Socs7 |
T |
C |
11: 97,263,950 (GRCm39) |
F281L |
probably benign |
Het |
| Spta1 |
C |
T |
1: 174,040,180 (GRCm39) |
L1214F |
probably benign |
Het |
| Ssu72 |
A |
G |
4: 155,789,900 (GRCm39) |
E21G |
probably damaging |
Het |
| Syngr4 |
A |
G |
7: 45,536,464 (GRCm39) |
V186A |
probably benign |
Het |
| Tars3 |
G |
A |
7: 65,305,539 (GRCm39) |
M254I |
possibly damaging |
Het |
| Tmem130 |
C |
A |
5: 144,680,595 (GRCm39) |
V270L |
probably benign |
Het |
| Trim66 |
A |
T |
7: 109,074,320 (GRCm39) |
I647N |
probably damaging |
Het |
| Tspyl2 |
A |
T |
X: 151,121,890 (GRCm39) |
D572E |
probably benign |
Het |
| Unc45b |
G |
A |
11: 82,808,580 (GRCm39) |
R222H |
probably benign |
Het |
| Uxs1 |
T |
C |
1: 43,866,783 (GRCm39) |
Y29C |
probably damaging |
Het |
| Virma |
T |
A |
4: 11,548,726 (GRCm39) |
|
probably benign |
Het |
| Vmn1r202 |
C |
T |
13: 22,685,953 (GRCm39) |
G155S |
possibly damaging |
Het |
| Vmn2r24 |
T |
A |
6: 123,755,972 (GRCm39) |
F15I |
probably benign |
Het |
| Wdr64 |
A |
G |
1: 175,594,661 (GRCm39) |
T471A |
probably benign |
Het |
| Zfa-ps |
T |
A |
10: 52,419,373 (GRCm39) |
|
noncoding transcript |
Het |
| Zfp260 |
A |
G |
7: 29,804,765 (GRCm39) |
K222E |
probably damaging |
Het |
| Zfp300 |
A |
G |
X: 20,948,190 (GRCm39) |
S525P |
possibly damaging |
Het |
| Zfp821 |
A |
G |
8: 110,450,979 (GRCm39) |
D324G |
probably damaging |
Het |
| Zfp934 |
T |
C |
13: 62,665,648 (GRCm39) |
D331G |
probably damaging |
Het |
| Zscan29 |
T |
C |
2: 121,000,587 (GRCm39) |
R7G |
probably damaging |
Het |
|
| Other mutations in Rictor |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00488:Rictor
|
APN |
15 |
6,816,071 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00785:Rictor
|
APN |
15 |
6,806,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00801:Rictor
|
APN |
15 |
6,824,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Rictor
|
APN |
15 |
6,819,043 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01139:Rictor
|
APN |
15 |
6,807,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01303:Rictor
|
APN |
15 |
6,738,119 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01307:Rictor
|
APN |
15 |
6,804,085 (GRCm39) |
splice site |
probably null |
|
|
IGL01767:Rictor
|
APN |
15 |
6,806,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01774:Rictor
|
APN |
15 |
6,799,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01800:Rictor
|
APN |
15 |
6,804,182 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02192:Rictor
|
APN |
15 |
6,815,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02503:Rictor
|
APN |
15 |
6,815,924 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02652:Rictor
|
APN |
15 |
6,805,668 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02656:Rictor
|
APN |
15 |
6,806,401 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02752:Rictor
|
APN |
15 |
6,816,852 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03000:Rictor
|
APN |
15 |
6,798,721 (GRCm39) |
splice site |
probably benign |
|
|
IGL03118:Rictor
|
APN |
15 |
6,788,999 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03182:Rictor
|
APN |
15 |
6,819,079 (GRCm39) |
missense |
probably benign |
0.08 |
|
Tense
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Tonus
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
Torrid
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0288:Rictor
|
UTSW |
15 |
6,816,021 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0304:Rictor
|
UTSW |
15 |
6,815,852 (GRCm39) |
splice site |
probably null |
|
|
R0336:Rictor
|
UTSW |
15 |
6,806,234 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0361:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0423:Rictor
|
UTSW |
15 |
6,803,381 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0453:Rictor
|
UTSW |
15 |
6,738,123 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0515:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Rictor
|
UTSW |
15 |
6,823,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0730:Rictor
|
UTSW |
15 |
6,803,467 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0836:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0881:Rictor
|
UTSW |
15 |
6,821,151 (GRCm39) |
missense |
probably benign |
|
|
R1114:Rictor
|
UTSW |
15 |
6,823,486 (GRCm39) |
nonsense |
probably null |
|
|
R1367:Rictor
|
UTSW |
15 |
6,820,119 (GRCm39) |
splice site |
probably benign |
|
|
R1655:Rictor
|
UTSW |
15 |
6,801,693 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1678:Rictor
|
UTSW |
15 |
6,785,952 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1679:Rictor
|
UTSW |
15 |
6,797,571 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1754:Rictor
|
UTSW |
15 |
6,764,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1757:Rictor
|
UTSW |
15 |
6,803,343 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1762:Rictor
|
UTSW |
15 |
6,786,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1914:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1915:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1994:Rictor
|
UTSW |
15 |
6,805,637 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2182:Rictor
|
UTSW |
15 |
6,801,685 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2191:Rictor
|
UTSW |
15 |
6,789,095 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2357:Rictor
|
UTSW |
15 |
6,813,043 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Rictor
|
UTSW |
15 |
6,799,476 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3082:Rictor
|
UTSW |
15 |
6,804,338 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3885:Rictor
|
UTSW |
15 |
6,789,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Rictor
|
UTSW |
15 |
6,818,954 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4376:Rictor
|
UTSW |
15 |
6,816,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4611:Rictor
|
UTSW |
15 |
6,816,625 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4644:Rictor
|
UTSW |
15 |
6,807,416 (GRCm39) |
nonsense |
probably null |
|
|
R4718:Rictor
|
UTSW |
15 |
6,812,641 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4822:Rictor
|
UTSW |
15 |
6,821,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4980:Rictor
|
UTSW |
15 |
6,811,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5034:Rictor
|
UTSW |
15 |
6,797,576 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5179:Rictor
|
UTSW |
15 |
6,825,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Rictor
|
UTSW |
15 |
6,818,985 (GRCm39) |
missense |
probably benign |
0.37 |
|
R5532:Rictor
|
UTSW |
15 |
6,819,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5549:Rictor
|
UTSW |
15 |
6,816,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Rictor
|
UTSW |
15 |
6,780,197 (GRCm39) |
nonsense |
probably null |
|
|
R5733:Rictor
|
UTSW |
15 |
6,812,585 (GRCm39) |
missense |
probably benign |
|
|
R5822:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5848:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5849:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5850:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5854:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5855:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5856:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5936:Rictor
|
UTSW |
15 |
6,813,642 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6155:Rictor
|
UTSW |
15 |
6,823,458 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6394:Rictor
|
UTSW |
15 |
6,798,790 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6549:Rictor
|
UTSW |
15 |
6,825,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6611:Rictor
|
UTSW |
15 |
6,780,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6657:Rictor
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6705:Rictor
|
UTSW |
15 |
6,823,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6819:Rictor
|
UTSW |
15 |
6,825,517 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6985:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6989:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7016:Rictor
|
UTSW |
15 |
6,804,361 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7030:Rictor
|
UTSW |
15 |
6,737,934 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7066:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7067:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7216:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7396:Rictor
|
UTSW |
15 |
6,816,462 (GRCm39) |
missense |
not run |
|
|
R7449:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7450:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7452:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7616:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7620:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7643:Rictor
|
UTSW |
15 |
6,798,750 (GRCm39) |
nonsense |
probably null |
|
|
R7699:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7700:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7749:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7750:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7751:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7753:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7841:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7894:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7897:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7898:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7937:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7944:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8062:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8063:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8094:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8119:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8134:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8166:Rictor
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8324:Rictor
|
UTSW |
15 |
6,775,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8343:Rictor
|
UTSW |
15 |
6,807,800 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8691:Rictor
|
UTSW |
15 |
6,816,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8859:Rictor
|
UTSW |
15 |
6,813,067 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8953:Rictor
|
UTSW |
15 |
6,823,928 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8977:Rictor
|
UTSW |
15 |
6,812,566 (GRCm39) |
missense |
probably benign |
|
|
R9008:Rictor
|
UTSW |
15 |
6,801,610 (GRCm39) |
splice site |
probably benign |
|
|
R9369:Rictor
|
UTSW |
15 |
6,773,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9563:Rictor
|
UTSW |
15 |
6,797,562 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9695:Rictor
|
UTSW |
15 |
6,816,010 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0020:Rictor
|
UTSW |
15 |
6,785,963 (GRCm39) |
missense |
probably benign |
0.32 |
|
X0060:Rictor
|
UTSW |
15 |
6,816,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCTTTAGAGTAGACCTGGTC -3'
(R):5'- AACTCAGAATACAGGATGCAGTATC -3'
Sequencing Primer
(F):5'- GAGTAGACCTGGTCTTTTTCAGAAC -3'
(R):5'- TCTCCTTGACTACCATACAT -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation