Mutagenetix > Incidental Mutation

Incidental Mutation 'R2146:Fat3'

233838

Institutional Source

Beutler Lab

Gene Symbol

Fat3

Ensembl Gene

ENSMUSG00000074505

Gene Name

FAT atypical cadherin 3

Synonyms

D430038H04Rik, LOC382129, LOC234973, 9430076A06Rik

MMRRC Submission

040149-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.631) question?

Stock #

R2146 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

15821485-16412581 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 15901808 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 3072 (F3072L)

Ref Sequence

ENSEMBL: ENSMUSP00000148968 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082170] [ENSMUST00000217308]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000082170
AA Change: F3072L

PolyPhen 2 Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000080808
Gene: ENSMUSG00000074505
AA Change: F3072L

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
CA	65	151	3e-7	SMART
CA	175	259	8.9e-22	SMART
CA	280	368	8.9e-4	SMART
CA	389	465	2.6e-11	SMART
CA	489	571	2e-29	SMART
low complexity region	684	697	N/A	INTRINSIC
CA	743	824	1e-24	SMART
low complexity region	830	840	N/A	INTRINSIC
CA	848	929	7.6e-26	SMART
CA	953	1034	1.5e-25	SMART
CA	1060	1141	6.6e-32	SMART
CA	1165	1247	1.5e-30	SMART
CA	1273	1349	1.8e-8	SMART
CA	1375	1453	2.9e-12	SMART
CA	1477	1559	3e-22	SMART
CA	1583	1664	3.1e-16	SMART
CA	1688	1762	4.2e-22	SMART
CA	1793	1876	2.5e-26	SMART
CA	1900	1975	1.5e-8	SMART
low complexity region	1983	1994	N/A	INTRINSIC
CA	1999	2077	1.4e-18	SMART
CA	2101	2179	6.6e-10	SMART
CA	2203	2280	4.9e-19	SMART
CA	2304	2387	4.3e-29	SMART
CA	2411	2489	4.2e-11	SMART
CA	2513	2593	2.8e-22	SMART
CA	2617	2701	4.3e-10	SMART
CA	2719	2807	2.5e-7	SMART
CA	2831	2917	3.3e-27	SMART
CA	2941	3022	9.4e-23	SMART
CA	3046	3124	2.4e-26	SMART
CA	3148	3229	1.3e-32	SMART
CA	3253	3334	1.3e-29	SMART
CA	3358	3439	4.9e-28	SMART
CA	3463	3544	6.4e-12	SMART
EGF	3793	3828	1.3e-1	SMART
LamG	3852	3989	4.3e-25	SMART
EGF	4019	4053	2.7e-6	SMART
EGF	4058	4091	4.5e-6	SMART
EGF_CA	4093	4129	3.9e-11	SMART
transmembrane domain	4151	4170	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000217308
AA Change: F3072L

PolyPhen 2 Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)

Meta Mutation Damage Score

0.0618

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.4%
20x: 95.4%

Validation Efficiency

99% (84/85)

MGI Phenotype

PHENOTYPE: Mice homozgyous for a knock-out allele exhibit abnormal amacrine cell differentiation and migration that result in the formation of two additional plexiform layers and thickened retinal ganglion layer. [provided by MGI curators]

Allele List at MGI

All alleles(3) : Gene trapped(3)

Other mutations in this stock

Total: 85 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700013D24Rik	A	T	6: 124,324,803 (GRCm39)		probably null	Het
9530002B09Rik	T	A	4: 122,583,198 (GRCm39)	C13*	probably null	Het
Abca12	C	A	1: 71,302,647 (GRCm39)	V2191L	probably benign	Het
Adamts18	G	C	8: 114,571,635 (GRCm39)	A116G	possibly damaging	Het
Anxa2	TCCC	TCC	9: 69,397,036 (GRCm39)		probably null	Het
Arfgef1	C	T	1: 10,270,103 (GRCm39)	A349T	probably benign	Het
Arhgap6	A	G	X: 167,579,496 (GRCm39)	T94A	probably benign	Het
Arhgef5	T	C	6: 43,260,252 (GRCm39)	S1413P	probably damaging	Het
Atg4c	C	A	4: 99,109,463 (GRCm39)	N143K	possibly damaging	Het
C1qtnf12	A	G	4: 156,050,922 (GRCm39)	N297S	probably benign	Het
Cadps2	G	T	6: 23,838,998 (GRCm39)		probably benign	Het
Ccdc185	G	T	1: 182,575,085 (GRCm39)	H535N	possibly damaging	Het
Ccdc57	A	G	11: 120,776,051 (GRCm39)		probably benign	Het
Cd163	A	G	6: 124,286,167 (GRCm39)	H239R	probably damaging	Het
Ceacam2	G	T	7: 25,227,368 (GRCm39)	C166*	probably null	Het
Ces5a	T	A	8: 94,261,327 (GRCm39)	E33D	probably benign	Het
Chl1	T	C	6: 103,692,362 (GRCm39)		probably null	Het
Chsy3	G	A	18: 59,309,544 (GRCm39)	V266I	probably benign	Het
Cpa5	G	T	6: 30,626,821 (GRCm39)	R251L	probably damaging	Het
Cps1	A	C	1: 67,191,538 (GRCm39)		probably benign	Het
Csmd3	CCTTTGCGCTT	CCTT	15: 47,604,632 (GRCm39)		probably null	Het
Cstf1	T	C	2: 172,217,683 (GRCm39)	Y99H	probably damaging	Het
Cyp2j11	G	A	4: 96,204,595 (GRCm39)	T317I	probably damaging	Het
Dcaf8l	T	C	X: 88,449,883 (GRCm39)	D82G	possibly damaging	Het
Dennd3	C	T	15: 73,395,345 (GRCm39)	T146M	probably damaging	Het
Dennd3	A	T	15: 73,426,909 (GRCm39)	H762L	probably benign	Het
Dnah2	T	C	11: 69,406,587 (GRCm39)	M552V	probably benign	Het
Dnajc22	T	C	15: 99,002,264 (GRCm39)	V303A	probably benign	Het
Dtx2	T	G	5: 136,059,464 (GRCm39)	L458R	probably benign	Het
Fgf5	T	C	5: 98,423,409 (GRCm39)	*265R	probably null	Het
Fndc11	A	G	2: 180,863,918 (GRCm39)	E241G	probably damaging	Het
Glb1	T	C	9: 114,279,716 (GRCm39)	Y375H	probably damaging	Het
Gm4922	T	G	10: 18,659,264 (GRCm39)	Q486P	probably benign	Het
Gm5786	A	T	12: 59,128,084 (GRCm39)		noncoding transcript	Het
Hepacam2	A	T	6: 3,463,378 (GRCm39)		probably benign	Het
Ints9	G	A	14: 65,223,792 (GRCm39)	G89R	possibly damaging	Het
Iqcm	T	A	8: 76,615,241 (GRCm39)	W441R	probably damaging	Het
Itga10	T	C	3: 96,558,808 (GRCm39)	L382P	possibly damaging	Het
Itga10	G	T	3: 96,561,039 (GRCm39)	G635W	probably damaging	Het
Kbtbd2	A	G	6: 56,756,075 (GRCm39)	Y554H	probably damaging	Het
Kif1b	T	C	4: 149,268,766 (GRCm39)	K1649R	probably damaging	Het
L1cam	A	T	X: 72,904,747 (GRCm39)	F536Y	probably damaging	Het
Magee1	A	T	X: 104,166,564 (GRCm39)	D783V	probably damaging	Het
Marveld3	A	T	8: 110,686,434 (GRCm39)	V144E	probably benign	Het
Mcam	T	C	9: 44,047,932 (GRCm39)	V59A	probably damaging	Het
Mdga2	C	T	12: 66,915,515 (GRCm39)	E47K	probably damaging	Het
Metrn	T	A	17: 26,015,601 (GRCm39)	E38V	probably damaging	Het
Mfrp	T	C	9: 44,015,015 (GRCm39)	L314P	probably benign	Het
Mgat4f	T	A	1: 134,318,251 (GRCm39)	M341K	probably damaging	Het
Mideas	G	T	12: 84,219,809 (GRCm39)	P382T	probably damaging	Het
Mospd2	A	G	X: 163,739,473 (GRCm39)		probably null	Het
Mycbp2	G	A	14: 103,393,358 (GRCm39)	H3068Y	probably damaging	Het
Myh6	C	T	14: 55,191,228 (GRCm39)	R871H	probably damaging	Het
Nup214	C	T	2: 31,924,478 (GRCm39)	S1669F	probably damaging	Het
Or13c7b	A	G	4: 43,821,178 (GRCm39)	F61S	probably damaging	Het
Or5b111	T	C	19: 13,291,485 (GRCm39)	T55A	probably benign	Het
Or8i2	T	A	2: 86,852,009 (GRCm39)	N293I	probably damaging	Het
Parvb	A	G	15: 84,116,369 (GRCm39)	K33E	possibly damaging	Het
Pdcd11	A	G	19: 47,093,191 (GRCm39)	M490V	probably benign	Het
Pkd2	A	C	5: 104,603,456 (GRCm39)		probably benign	Het
Reps1	T	A	10: 17,969,061 (GRCm39)	D206E	probably benign	Het
Rimkla	T	A	4: 119,331,779 (GRCm39)	M140L	possibly damaging	Het
Rnf13	T	G	3: 57,709,907 (GRCm39)	I150S	probably null	Het
Rxfp4	C	T	3: 88,560,200 (GRCm39)	A84T	probably damaging	Het
Serpinb8	T	A	1: 107,533,657 (GRCm39)	D237E	probably benign	Het
Sgo2b	T	G	8: 64,381,057 (GRCm39)	T592P	probably benign	Het
Slc35d1	A	T	4: 103,062,349 (GRCm39)	I228N	probably damaging	Het
Slc39a1	T	G	3: 90,156,757 (GRCm39)	H104Q	probably benign	Het
Slc6a6	T	C	6: 91,712,161 (GRCm39)	V230A	probably benign	Het
Slc9a3	A	G	13: 74,269,722 (GRCm39)	E30G	probably benign	Het
Slc9c1	A	G	16: 45,413,827 (GRCm39)	Y985C	probably benign	Het
Supt6	A	G	11: 78,121,758 (GRCm39)	F298S	probably damaging	Het
Tada2a	T	C	11: 83,970,455 (GRCm39)	D432G	probably damaging	Het
Thoc2l	T	C	5: 104,666,857 (GRCm39)	F460L	probably benign	Het
Tmem131	C	A	1: 36,851,690 (GRCm39)	V938L	probably benign	Het
Tnpo3	A	G	6: 29,589,035 (GRCm39)	V105A	probably benign	Het
Ttc7	T	C	17: 87,654,135 (GRCm39)		probably benign	Het
Ttn	T	C	2: 76,727,532 (GRCm39)		probably benign	Het
Usp16	T	C	16: 87,270,075 (GRCm39)		probably null	Het
Usp36	A	G	11: 118,159,491 (GRCm39)	L486S	probably benign	Het
Uty	T	C	Y: 1,239,816 (GRCm39)	I72V	probably benign	Het
Vps51	A	G	19: 6,118,164 (GRCm39)	V777A	probably benign	Het
Zfp160	A	G	17: 21,247,244 (GRCm39)	K598R	probably benign	Het
Zfp39	T	C	11: 58,781,158 (GRCm39)	N535D	probably benign	Het
Zfp804a	A	G	2: 82,089,008 (GRCm39)	T946A	probably benign	Het

Other mutations in Fat3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00662:Fat3	APN	9	15,907,723 (GRCm39)	missense	possibly damaging	0.77
IGL00962:Fat3	APN	9	15,826,815 (GRCm39)	missense	probably benign	0.14
IGL00966:Fat3	APN	9	15,910,390 (GRCm39)	missense	possibly damaging	0.69
IGL01100:Fat3	APN	9	16,286,524 (GRCm39)	missense	probably damaging	1.00
IGL01104:Fat3	APN	9	16,287,024 (GRCm39)	missense	possibly damaging	0.92
IGL01104:Fat3	APN	9	15,909,756 (GRCm39)	missense	probably damaging	1.00
IGL01121:Fat3	APN	9	15,909,697 (GRCm39)	missense	probably benign	0.00
IGL01407:Fat3	APN	9	16,289,319 (GRCm39)	missense	probably benign	0.01
IGL01444:Fat3	APN	9	15,910,144 (GRCm39)	missense	probably damaging	1.00
IGL01634:Fat3	APN	9	15,909,654 (GRCm39)	missense	probably damaging	1.00
IGL01649:Fat3	APN	9	16,288,015 (GRCm39)	missense	possibly damaging	0.95
IGL01839:Fat3	APN	9	15,909,168 (GRCm39)	missense	probably damaging	1.00
IGL01867:Fat3	APN	9	16,289,197 (GRCm39)	missense	probably benign	0.03
IGL01894:Fat3	APN	9	16,287,145 (GRCm39)	missense	probably benign
IGL01913:Fat3	APN	9	15,910,086 (GRCm39)	missense	probably damaging	0.99
IGL02033:Fat3	APN	9	15,826,648 (GRCm39)	missense	possibly damaging	0.50
IGL02035:Fat3	APN	9	16,289,266 (GRCm39)	missense	probably benign	0.06
IGL02146:Fat3	APN	9	15,910,878 (GRCm39)	missense	probably benign
IGL02147:Fat3	APN	9	15,907,281 (GRCm39)	missense	probably damaging	1.00
IGL02161:Fat3	APN	9	15,908,346 (GRCm39)	missense	probably benign	0.10
IGL02161:Fat3	APN	9	15,908,347 (GRCm39)	nonsense	probably null
IGL02164:Fat3	APN	9	15,942,720 (GRCm39)	splice site	probably benign
IGL02269:Fat3	APN	9	15,826,873 (GRCm39)	missense	possibly damaging	0.84
IGL02314:Fat3	APN	9	15,881,134 (GRCm39)	missense	possibly damaging	0.61
IGL02393:Fat3	APN	9	15,899,708 (GRCm39)	nonsense	probably null
IGL02410:Fat3	APN	9	15,909,141 (GRCm39)	missense	probably damaging	1.00
IGL02504:Fat3	APN	9	15,871,094 (GRCm39)	missense	probably damaging	1.00
IGL02572:Fat3	APN	9	15,871,802 (GRCm39)	missense	probably benign
IGL02623:Fat3	APN	9	15,908,433 (GRCm39)	missense	probably damaging	1.00
IGL02654:Fat3	APN	9	15,908,271 (GRCm39)	missense	possibly damaging	0.84
IGL02749:Fat3	APN	9	15,918,007 (GRCm39)	missense	possibly damaging	0.93
IGL02810:Fat3	APN	9	16,288,146 (GRCm39)	missense	probably damaging	1.00
IGL02839:Fat3	APN	9	15,830,466 (GRCm39)	missense	probably damaging	1.00
IGL02890:Fat3	APN	9	15,826,636 (GRCm39)	missense	probably benign	0.03
IGL02892:Fat3	APN	9	16,288,858 (GRCm39)	missense	probably damaging	1.00
IGL03090:Fat3	APN	9	16,288,535 (GRCm39)	nonsense	probably null
IGL03144:Fat3	APN	9	16,286,541 (GRCm39)	missense	probably damaging	1.00
IGL03199:Fat3	APN	9	16,288,344 (GRCm39)	missense	possibly damaging	0.83
IGL03365:Fat3	APN	9	15,907,765 (GRCm39)	missense	probably damaging	1.00
IGL03392:Fat3	APN	9	15,915,158 (GRCm39)	missense	probably benign
IGL03408:Fat3	APN	9	15,909,253 (GRCm39)	nonsense	probably null
gagged	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
hushed	UTSW	9	15,871,165 (GRCm39)	missense	possibly damaging	0.72
Muffled	UTSW	9	15,849,287 (GRCm39)	critical splice donor site	probably null
muted	UTSW	9	15,908,773 (GRCm39)	missense	possibly damaging	0.93
Softened	UTSW	9	16,289,481 (GRCm39)	missense	probably benign
BB001:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
BB002:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
BB011:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
BB012:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
F6893:Fat3	UTSW	9	15,918,085 (GRCm39)	missense	probably damaging	0.99
IGL03050:Fat3	UTSW	9	15,907,896 (GRCm39)	missense	probably benign	0.04
PIT4142001:Fat3	UTSW	9	15,903,414 (GRCm39)	critical splice donor site	probably null
PIT4283001:Fat3	UTSW	9	15,917,897 (GRCm39)	missense	possibly damaging	0.77
PIT4378001:Fat3	UTSW	9	16,288,104 (GRCm39)	missense	probably benign	0.05
PIT4434001:Fat3	UTSW	9	15,907,612 (GRCm39)	missense	probably benign	0.00
PIT4468001:Fat3	UTSW	9	15,907,647 (GRCm39)	missense	probably benign	0.06
R0001:Fat3	UTSW	9	16,289,169 (GRCm39)	missense	probably damaging	0.99
R0005:Fat3	UTSW	9	15,874,162 (GRCm39)	missense	probably damaging	1.00
R0005:Fat3	UTSW	9	15,874,162 (GRCm39)	missense	probably damaging	1.00
R0038:Fat3	UTSW	9	15,826,306 (GRCm39)	missense	probably damaging	1.00
R0046:Fat3	UTSW	9	15,877,275 (GRCm39)	missense	possibly damaging	0.65
R0089:Fat3	UTSW	9	15,849,501 (GRCm39)	missense	probably benign
R0135:Fat3	UTSW	9	15,918,073 (GRCm39)	missense	probably damaging	1.00
R0255:Fat3	UTSW	9	15,881,002 (GRCm39)	splice site	probably benign
R0349:Fat3	UTSW	9	15,942,476 (GRCm39)	missense	probably damaging	1.00
R0361:Fat3	UTSW	9	15,909,699 (GRCm39)	missense	possibly damaging	0.77
R0382:Fat3	UTSW	9	15,871,052 (GRCm39)	missense	probably damaging	1.00
R0418:Fat3	UTSW	9	16,158,192 (GRCm39)	missense	probably damaging	1.00
R0419:Fat3	UTSW	9	15,903,552 (GRCm39)	missense	probably damaging	1.00
R0437:Fat3	UTSW	9	15,908,228 (GRCm39)	missense	probably damaging	1.00
R0441:Fat3	UTSW	9	15,856,304 (GRCm39)	splice site	probably benign
R0480:Fat3	UTSW	9	15,909,025 (GRCm39)	missense	probably benign	0.00
R0510:Fat3	UTSW	9	15,910,981 (GRCm39)	nonsense	probably null
R0665:Fat3	UTSW	9	15,908,698 (GRCm39)	missense	probably benign
R0715:Fat3	UTSW	9	16,286,419 (GRCm39)	missense	probably benign
R0727:Fat3	UTSW	9	15,907,995 (GRCm39)	missense	probably damaging	1.00
R0882:Fat3	UTSW	9	15,942,664 (GRCm39)	missense	possibly damaging	0.84
R0946:Fat3	UTSW	9	15,909,100 (GRCm39)	missense	possibly damaging	0.95
R1068:Fat3	UTSW	9	15,881,330 (GRCm39)	missense	probably benign
R1081:Fat3	UTSW	9	16,286,580 (GRCm39)	missense	possibly damaging	0.62
R1082:Fat3	UTSW	9	15,917,911 (GRCm39)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,908,070 (GRCm39)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,908,070 (GRCm39)	missense	probably damaging	1.00
R1233:Fat3	UTSW	9	15,834,041 (GRCm39)	missense	probably benign
R1306:Fat3	UTSW	9	16,287,975 (GRCm39)	missense	probably damaging	1.00
R1311:Fat3	UTSW	9	15,932,706 (GRCm39)	missense	probably damaging	1.00
R1338:Fat3	UTSW	9	15,836,387 (GRCm39)	missense	probably benign	0.00
R1395:Fat3	UTSW	9	16,158,212 (GRCm39)	missense	probably benign	0.00
R1466:Fat3	UTSW	9	16,286,778 (GRCm39)	missense	probably damaging	0.96
R1466:Fat3	UTSW	9	16,286,778 (GRCm39)	missense	probably damaging	0.96
R1510:Fat3	UTSW	9	15,871,351 (GRCm39)	missense	probably damaging	1.00
R1528:Fat3	UTSW	9	15,836,387 (GRCm39)	missense	probably benign	0.00
R1531:Fat3	UTSW	9	15,908,761 (GRCm39)	missense	probably damaging	1.00
R1659:Fat3	UTSW	9	15,908,479 (GRCm39)	missense	possibly damaging	0.91
R1697:Fat3	UTSW	9	15,856,176 (GRCm39)	missense	probably benign	0.05
R1699:Fat3	UTSW	9	15,849,694 (GRCm39)	missense	probably damaging	1.00
R1728:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1729:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1731:Fat3	UTSW	9	15,907,233 (GRCm39)	missense	probably benign
R1784:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1789:Fat3	UTSW	9	16,288,281 (GRCm39)	missense	probably benign	0.00
R1794:Fat3	UTSW	9	15,908,434 (GRCm39)	missense	probably benign	0.15
R1794:Fat3	UTSW	9	15,908,432 (GRCm39)	nonsense	probably null
R1830:Fat3	UTSW	9	15,826,636 (GRCm39)	missense	probably benign	0.03
R1835:Fat3	UTSW	9	15,909,384 (GRCm39)	missense	probably damaging	1.00
R1887:Fat3	UTSW	9	15,878,357 (GRCm39)	missense	probably damaging	1.00
R1898:Fat3	UTSW	9	15,871,426 (GRCm39)	missense	probably damaging	1.00
R1909:Fat3	UTSW	9	15,909,411 (GRCm39)	missense	probably benign
R1912:Fat3	UTSW	9	15,881,284 (GRCm39)	missense	probably damaging	1.00
R1917:Fat3	UTSW	9	15,908,353 (GRCm39)	missense	possibly damaging	0.55
R1967:Fat3	UTSW	9	15,879,591 (GRCm39)	missense	probably benign	0.00
R2070:Fat3	UTSW	9	15,910,666 (GRCm39)	missense	probably benign	0.21
R2100:Fat3	UTSW	9	16,288,726 (GRCm39)	missense	possibly damaging	0.73
R2104:Fat3	UTSW	9	15,909,813 (GRCm39)	missense	possibly damaging	0.77
R2113:Fat3	UTSW	9	15,911,082 (GRCm39)	missense	probably damaging	1.00
R2132:Fat3	UTSW	9	16,158,015 (GRCm39)	critical splice donor site	probably null
R2136:Fat3	UTSW	9	16,288,347 (GRCm39)	missense	probably benign	0.01
R2233:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2234:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2273:Fat3	UTSW	9	15,826,558 (GRCm39)	missense	probably benign
R2285:Fat3	UTSW	9	16,287,469 (GRCm39)	missense	probably damaging	1.00
R2363:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2365:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2367:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2403:Fat3	UTSW	9	15,881,167 (GRCm39)	missense	probably damaging	1.00
R2447:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2496:Fat3	UTSW	9	15,877,399 (GRCm39)	missense	probably benign	0.01
R2509:Fat3	UTSW	9	15,836,310 (GRCm39)	missense	possibly damaging	0.82
R2932:Fat3	UTSW	9	16,287,240 (GRCm39)	missense	probably damaging	1.00
R2986:Fat3	UTSW	9	15,903,424 (GRCm39)	missense	probably damaging	1.00
R3054:Fat3	UTSW	9	15,871,792 (GRCm39)	missense	probably benign
R3056:Fat3	UTSW	9	15,871,792 (GRCm39)	missense	probably benign
R3729:Fat3	UTSW	9	16,158,337 (GRCm39)	splice site	probably benign
R3745:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3806:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3859:Fat3	UTSW	9	15,908,524 (GRCm39)	nonsense	probably null
R3862:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3890:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3892:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3950:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3972:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4004:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4005:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4086:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4111:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4113:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4227:Fat3	UTSW	9	16,288,989 (GRCm39)	missense	probably damaging	1.00
R4352:Fat3	UTSW	9	16,158,074 (GRCm39)	missense	possibly damaging	0.55
R4394:Fat3	UTSW	9	15,834,088 (GRCm39)	missense	probably benign	0.11
R4403:Fat3	UTSW	9	15,856,169 (GRCm39)	missense	probably damaging	1.00
R4433:Fat3	UTSW	9	15,942,448 (GRCm39)	missense	probably damaging	0.99
R4453:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4479:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4480:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4521:Fat3	UTSW	9	15,834,238 (GRCm39)	missense	probably null	0.71
R4620:Fat3	UTSW	9	15,908,190 (GRCm39)	missense	probably damaging	1.00
R4700:Fat3	UTSW	9	15,942,469 (GRCm39)	missense	probably damaging	1.00
R4721:Fat3	UTSW	9	15,941,262 (GRCm39)	missense	probably damaging	1.00
R4790:Fat3	UTSW	9	15,909,780 (GRCm39)	missense	probably damaging	1.00
R4796:Fat3	UTSW	9	15,911,028 (GRCm39)	missense	probably benign	0.17
R4823:Fat3	UTSW	9	15,907,803 (GRCm39)	missense	probably benign
R4836:Fat3	UTSW	9	16,289,019 (GRCm39)	missense	probably damaging	1.00
R4842:Fat3	UTSW	9	15,908,883 (GRCm39)	missense	probably damaging	1.00
R4849:Fat3	UTSW	9	16,289,244 (GRCm39)	missense	probably benign	0.03
R4856:Fat3	UTSW	9	15,932,626 (GRCm39)	missense	probably benign
R4869:Fat3	UTSW	9	16,288,773 (GRCm39)	missense	probably damaging	0.98
R4886:Fat3	UTSW	9	15,932,626 (GRCm39)	missense	probably benign
R4899:Fat3	UTSW	9	15,881,095 (GRCm39)	missense	probably damaging	1.00
R4941:Fat3	UTSW	9	16,286,448 (GRCm39)	missense	probably damaging	1.00
R4986:Fat3	UTSW	9	15,909,636 (GRCm39)	missense	probably damaging	1.00
R5058:Fat3	UTSW	9	15,908,154 (GRCm39)	missense	probably damaging	1.00
R5079:Fat3	UTSW	9	15,910,423 (GRCm39)	missense	probably benign	0.01
R5080:Fat3	UTSW	9	15,910,634 (GRCm39)	missense	probably benign	0.35
R5174:Fat3	UTSW	9	15,910,866 (GRCm39)	missense	probably damaging	1.00
R5183:Fat3	UTSW	9	15,871,609 (GRCm39)	missense	probably damaging	0.99
R5203:Fat3	UTSW	9	16,289,438 (GRCm39)	missense	possibly damaging	0.79
R5216:Fat3	UTSW	9	16,288,833 (GRCm39)	missense	probably damaging	1.00
R5230:Fat3	UTSW	9	15,901,856 (GRCm39)	missense	possibly damaging	0.51
R5318:Fat3	UTSW	9	16,287,925 (GRCm39)	missense	probably damaging	1.00
R5377:Fat3	UTSW	9	16,287,739 (GRCm39)	missense	probably benign	0.05
R5385:Fat3	UTSW	9	15,833,971 (GRCm39)	missense	possibly damaging	0.82
R5436:Fat3	UTSW	9	15,871,810 (GRCm39)	missense	probably benign	0.02
R5437:Fat3	UTSW	9	15,996,604 (GRCm39)	missense	probably damaging	1.00
R5453:Fat3	UTSW	9	15,908,160 (GRCm39)	missense	probably damaging	1.00
R5460:Fat3	UTSW	9	15,830,463 (GRCm39)	missense	probably damaging	1.00
R5516:Fat3	UTSW	9	15,910,005 (GRCm39)	missense	probably damaging	1.00
R5568:Fat3	UTSW	9	16,288,219 (GRCm39)	nonsense	probably null
R5628:Fat3	UTSW	9	15,877,392 (GRCm39)	missense	probably damaging	1.00
R5835:Fat3	UTSW	9	16,287,129 (GRCm39)	missense	probably damaging	1.00
R5845:Fat3	UTSW	9	16,288,506 (GRCm39)	missense	probably damaging	1.00
R5898:Fat3	UTSW	9	15,849,757 (GRCm39)	missense	probably benign	0.15
R5941:Fat3	UTSW	9	15,910,797 (GRCm39)	missense	probably benign	0.07
R5974:Fat3	UTSW	9	15,917,824 (GRCm39)	critical splice donor site	probably null
R5986:Fat3	UTSW	9	15,909,613 (GRCm39)	missense	probably benign	0.22
R6015:Fat3	UTSW	9	16,287,346 (GRCm39)	missense	possibly damaging	0.55
R6031:Fat3	UTSW	9	15,899,788 (GRCm39)	missense	probably benign	0.02
R6031:Fat3	UTSW	9	15,899,788 (GRCm39)	missense	probably benign	0.02
R6042:Fat3	UTSW	9	16,289,113 (GRCm39)	missense	probably benign	0.12
R6051:Fat3	UTSW	9	16,286,751 (GRCm39)	missense	possibly damaging	0.83
R6052:Fat3	UTSW	9	15,833,975 (GRCm39)	missense	probably null
R6119:Fat3	UTSW	9	16,287,864 (GRCm39)	missense	possibly damaging	0.82
R6161:Fat3	UTSW	9	16,288,818 (GRCm39)	missense	probably damaging	1.00
R6254:Fat3	UTSW	9	15,907,441 (GRCm39)	missense	probably benign	0.19
R6318:Fat3	UTSW	9	15,828,280 (GRCm39)	intron	probably benign
R6347:Fat3	UTSW	9	15,909,668 (GRCm39)	missense	probably damaging	1.00
R6348:Fat3	UTSW	9	15,849,287 (GRCm39)	critical splice donor site	probably null
R6351:Fat3	UTSW	9	15,849,694 (GRCm39)	missense	probably damaging	1.00
R6450:Fat3	UTSW	9	15,910,466 (GRCm39)	missense	possibly damaging	0.51
R6460:Fat3	UTSW	9	15,878,296 (GRCm39)	missense	probably damaging	1.00
R6524:Fat3	UTSW	9	15,903,552 (GRCm39)	missense	probably damaging	1.00
R6533:Fat3	UTSW	9	15,910,195 (GRCm39)	missense	probably benign	0.02
R6565:Fat3	UTSW	9	15,826,623 (GRCm39)	missense	probably benign
R6576:Fat3	UTSW	9	16,288,506 (GRCm39)	missense	probably damaging	1.00
R6649:Fat3	UTSW	9	16,288,038 (GRCm39)	missense	probably damaging	1.00
R6716:Fat3	UTSW	9	15,830,565 (GRCm39)	missense	probably benign
R6719:Fat3	UTSW	9	15,907,440 (GRCm39)	missense	probably benign
R6753:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6754:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6755:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6792:Fat3	UTSW	9	16,286,940 (GRCm39)	missense	probably damaging	1.00
R6802:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6803:Fat3	UTSW	9	15,908,083 (GRCm39)	missense	probably damaging	0.99
R6831:Fat3	UTSW	9	16,287,847 (GRCm39)	missense	probably damaging	0.98
R6831:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6833:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6877:Fat3	UTSW	9	15,910,564 (GRCm39)	missense	probably benign
R6894:Fat3	UTSW	9	15,909,072 (GRCm39)	missense	probably damaging	1.00
R6915:Fat3	UTSW	9	16,289,044 (GRCm39)	missense	probably benign	0.37
R6931:Fat3	UTSW	9	15,871,238 (GRCm39)	missense	possibly damaging	0.89
R6934:Fat3	UTSW	9	16,288,252 (GRCm39)	missense	probably damaging	0.98
R6940:Fat3	UTSW	9	15,828,096 (GRCm39)	splice site	probably null
R6959:Fat3	UTSW	9	15,908,181 (GRCm39)	missense	possibly damaging	0.91
R6969:Fat3	UTSW	9	15,941,212 (GRCm39)	missense	probably benign	0.29
R6986:Fat3	UTSW	9	15,932,631 (GRCm39)	missense	probably damaging	1.00
R6993:Fat3	UTSW	9	15,830,517 (GRCm39)	missense	probably damaging	1.00
R7039:Fat3	UTSW	9	16,287,561 (GRCm39)	missense	probably damaging	1.00
R7051:Fat3	UTSW	9	16,289,123 (GRCm39)	missense	probably damaging	1.00
R7089:Fat3	UTSW	9	15,908,214 (GRCm39)	missense	probably benign	0.01
R7136:Fat3	UTSW	9	16,289,481 (GRCm39)	missense	probably benign
R7137:Fat3	UTSW	9	15,908,444 (GRCm39)	missense	probably damaging	1.00
R7154:Fat3	UTSW	9	15,908,160 (GRCm39)	missense	probably damaging	1.00
R7170:Fat3	UTSW	9	15,917,870 (GRCm39)	missense	probably damaging	0.99
R7183:Fat3	UTSW	9	15,834,133 (GRCm39)	missense	possibly damaging	0.81
R7237:Fat3	UTSW	9	16,288,510 (GRCm39)	missense	probably damaging	1.00
R7288:Fat3	UTSW	9	15,909,888 (GRCm39)	missense	probably damaging	1.00
R7293:Fat3	UTSW	9	15,826,592 (GRCm39)	missense
R7293:Fat3	UTSW	9	15,826,336 (GRCm39)	missense
R7381:Fat3	UTSW	9	16,158,283 (GRCm39)	missense	probably damaging	1.00
R7438:Fat3	UTSW	9	15,899,778 (GRCm39)	missense	probably benign
R7537:Fat3	UTSW	9	15,849,615 (GRCm39)	missense	probably damaging	1.00
R7560:Fat3	UTSW	9	15,908,138 (GRCm39)	missense	probably damaging	1.00
R7585:Fat3	UTSW	9	15,909,558 (GRCm39)	missense	probably benign	0.03
R7623:Fat3	UTSW	9	15,899,620 (GRCm39)	missense	probably damaging	1.00
R7624:Fat3	UTSW	9	15,871,165 (GRCm39)	missense	possibly damaging	0.72
R7684:Fat3	UTSW	9	15,899,564 (GRCm39)	critical splice donor site	probably null
R7690:Fat3	UTSW	9	15,909,477 (GRCm39)	missense	probably damaging	1.00
R7804:Fat3	UTSW	9	15,901,888 (GRCm39)	missense	probably benign	0.01
R7809:Fat3	UTSW	9	15,917,924 (GRCm39)	missense	probably damaging	1.00
R7924:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
R7925:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
R7954:Fat3	UTSW	9	15,909,708 (GRCm39)	missense	probably damaging	1.00
R8021:Fat3	UTSW	9	15,910,405 (GRCm39)	missense	probably damaging	0.99
R8118:Fat3	UTSW	9	15,871,400 (GRCm39)	missense	probably benign
R8141:Fat3	UTSW	9	15,908,362 (GRCm39)	missense	possibly damaging	0.79
R8163:Fat3	UTSW	9	15,871,055 (GRCm39)	missense	probably damaging	1.00
R8170:Fat3	UTSW	9	15,858,792 (GRCm39)	missense	probably damaging	0.97
R8201:Fat3	UTSW	9	15,908,773 (GRCm39)	missense	possibly damaging	0.93
R8258:Fat3	UTSW	9	15,901,887 (GRCm39)	missense	possibly damaging	0.79
R8259:Fat3	UTSW	9	15,901,887 (GRCm39)	missense	possibly damaging	0.79
R8274:Fat3	UTSW	9	16,288,786 (GRCm39)	nonsense	probably null
R8275:Fat3	UTSW	9	16,158,046 (GRCm39)	missense	probably damaging	1.00
R8345:Fat3	UTSW	9	15,910,570 (GRCm39)	missense	probably benign	0.08
R8350:Fat3	UTSW	9	15,826,435 (GRCm39)	missense
R8405:Fat3	UTSW	9	15,907,167 (GRCm39)	missense	probably damaging	1.00
R8421:Fat3	UTSW	9	15,909,480 (GRCm39)	missense	probably damaging	1.00
R8450:Fat3	UTSW	9	15,826,435 (GRCm39)	missense
R8472:Fat3	UTSW	9	16,286,563 (GRCm39)	missense	possibly damaging	0.90
R8482:Fat3	UTSW	9	16,158,263 (GRCm39)	missense	probably benign	0.02
R8680:Fat3	UTSW	9	15,908,703 (GRCm39)	missense	probably damaging	0.99
R8690:Fat3	UTSW	9	15,878,397 (GRCm39)	missense	probably benign	0.45
R8748:Fat3	UTSW	9	15,834,161 (GRCm39)	missense	possibly damaging	0.70
R8756:Fat3	UTSW	9	16,287,885 (GRCm39)	missense	probably damaging	1.00
R8834:Fat3	UTSW	9	15,942,493 (GRCm39)	missense	probably damaging	1.00
R8848:Fat3	UTSW	9	15,878,398 (GRCm39)	missense	probably damaging	1.00
R8884:Fat3	UTSW	9	15,941,280 (GRCm39)	missense	probably damaging	1.00
R8898:Fat3	UTSW	9	15,858,822 (GRCm39)	missense	probably benign	0.04
R8930:Fat3	UTSW	9	15,910,819 (GRCm39)	missense	probably benign	0.06
R8932:Fat3	UTSW	9	15,910,819 (GRCm39)	missense	probably benign	0.06
R8954:Fat3	UTSW	9	16,287,864 (GRCm39)	missense	probably benign	0.00
R8995:Fat3	UTSW	9	16,286,898 (GRCm39)	missense	probably damaging	1.00
R9000:Fat3	UTSW	9	15,918,095 (GRCm39)	missense	probably benign	0.12
R9000:Fat3	UTSW	9	15,871,816 (GRCm39)	missense	possibly damaging	0.82
R9060:Fat3	UTSW	9	15,910,782 (GRCm39)	missense	possibly damaging	0.80
R9116:Fat3	UTSW	9	15,909,421 (GRCm39)	missense	probably benign	0.34
R9136:Fat3	UTSW	9	15,833,738 (GRCm39)	missense
R9193:Fat3	UTSW	9	15,910,248 (GRCm39)	missense	probably benign
R9235:Fat3	UTSW	9	15,833,674 (GRCm39)	missense	probably null
R9257:Fat3	UTSW	9	15,907,863 (GRCm39)	missense	probably benign
R9297:Fat3	UTSW	9	15,908,996 (GRCm39)	missense	probably damaging	1.00
R9307:Fat3	UTSW	9	15,932,719 (GRCm39)	missense	probably damaging	1.00
R9412:Fat3	UTSW	9	15,908,703 (GRCm39)	missense	probably damaging	0.99
R9427:Fat3	UTSW	9	16,288,691 (GRCm39)	nonsense	probably null
R9430:Fat3	UTSW	9	16,287,381 (GRCm39)	missense	probably damaging	1.00
R9480:Fat3	UTSW	9	15,942,703 (GRCm39)	missense	probably damaging	1.00
R9497:Fat3	UTSW	9	15,903,504 (GRCm39)	missense	probably damaging	0.99
R9547:Fat3	UTSW	9	15,911,142 (GRCm39)	missense	possibly damaging	0.86
R9569:Fat3	UTSW	9	15,830,495 (GRCm39)	missense
R9591:Fat3	UTSW	9	16,288,336 (GRCm39)	missense	probably benign	0.01
R9615:Fat3	UTSW	9	16,289,343 (GRCm39)	missense	probably benign	0.00
R9649:Fat3	UTSW	9	15,908,054 (GRCm39)	missense	possibly damaging	0.57
R9671:Fat3	UTSW	9	16,286,871 (GRCm39)	missense	possibly damaging	0.93
R9750:Fat3	UTSW	9	15,915,157 (GRCm39)	missense	probably benign	0.00
R9777:Fat3	UTSW	9	15,826,537 (GRCm39)	missense	probably benign
RF006:Fat3	UTSW	9	15,909,913 (GRCm39)	missense	probably benign	0.36
X0021:Fat3	UTSW	9	15,941,227 (GRCm39)	missense	probably null	0.66
X0026:Fat3	UTSW	9	15,907,629 (GRCm39)	missense	probably benign
X0064:Fat3	UTSW	9	15,830,573 (GRCm39)	missense	probably benign
Z1176:Fat3	UTSW	9	16,286,913 (GRCm39)	missense	probably benign
Z1176:Fat3	UTSW	9	16,286,725 (GRCm39)	missense	probably damaging	1.00
Z1176:Fat3	UTSW	9	15,858,822 (GRCm39)	missense	probably damaging	0.98
Z1177:Fat3	UTSW	9	15,877,287 (GRCm39)	missense	possibly damaging	0.68
Z1177:Fat3	UTSW	9	15,858,834 (GRCm39)	missense	probably damaging	1.00
Z1177:Fat3	UTSW	9	15,834,322 (GRCm39)	missense	possibly damaging	0.81
Z1177:Fat3	UTSW	9	15,881,131 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- ACATCTGTATACTGTGAAGCGC -3'
(R):5'- ACACTGCAATATGGTCGGAGG -3'

Sequencing Primer
(F):5'- GCGCTTATTTCTTAACATCTAGAGC -3'
(R):5'- CTGCAGGCAGTAATGATTGACTTAC -3'

Posted On

2014-10-01