Incidental Mutation 'R2153:Sned1'
| ID |
234461 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sned1
|
| Ensembl Gene |
ENSMUSG00000047793 |
| Gene Name |
sushi, nidogen and EGF-like domains 1 |
| Synonyms |
D430044C15Rik, 6720455I24Rik, Snep |
| MMRRC Submission |
040156-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.080)
|
| Stock # |
R2153 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
93163563-93228787 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 93202379 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 674
(D674E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000050832
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062202]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000062202
AA Change: D674E
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000050832
Gene: ENSMUSG00000047793
AA Change: D674E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
NIDO
|
103 |
260 |
2.98e-54 |
SMART |
|
EGF
|
271 |
309 |
3.79e-6 |
SMART |
|
EGF_CA
|
311 |
347 |
2.42e-13 |
SMART |
|
EGF
|
352 |
385 |
1.02e-6 |
SMART |
|
EGF_CA
|
387 |
423 |
1.91e-11 |
SMART |
|
EGF
|
432 |
465 |
2.96e-8 |
SMART |
|
EGF
|
471 |
500 |
6.02e0 |
SMART |
|
EGF
|
544 |
577 |
3.54e-6 |
SMART |
|
EGF
|
583 |
616 |
6.06e-5 |
SMART |
|
EGF_CA
|
619 |
655 |
2.33e-6 |
SMART |
|
EGF
|
660 |
693 |
1.77e-6 |
SMART |
|
CCP
|
698 |
751 |
2.5e-11 |
SMART |
|
EGF_CA
|
753 |
789 |
1.66e-11 |
SMART |
|
EGF_CA
|
791 |
827 |
1.38e-8 |
SMART |
|
EGF_CA
|
829 |
865 |
1.92e-7 |
SMART |
|
EGF
|
870 |
903 |
2.35e-2 |
SMART |
|
FN3
|
906 |
991 |
1.7e-4 |
SMART |
|
FN3
|
1005 |
1084 |
1.38e-4 |
SMART |
|
FN3
|
1104 |
1185 |
1.6e-9 |
SMART |
|
EGF
|
1309 |
1342 |
6.16e-6 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000165843
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000172289
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185062
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700030K09Rik |
A |
G |
8: 73,208,959 (GRCm39) |
E363G |
probably benign |
Het |
| Abcg2 |
T |
A |
6: 58,661,307 (GRCm39) |
|
probably null |
Het |
| Adgrg7 |
T |
G |
16: 56,572,791 (GRCm39) |
I342L |
possibly damaging |
Het |
| Akap6 |
A |
C |
12: 53,188,187 (GRCm39) |
D1867A |
probably benign |
Het |
| Ankrd17 |
A |
T |
5: 90,381,918 (GRCm39) |
V2416D |
probably damaging |
Het |
| Apaf1 |
A |
G |
10: 90,883,952 (GRCm39) |
V670A |
probably damaging |
Het |
| Art5 |
A |
G |
7: 101,747,407 (GRCm39) |
L124P |
possibly damaging |
Het |
| Atad5 |
T |
A |
11: 79,997,203 (GRCm39) |
D842E |
probably benign |
Het |
| Brd10 |
T |
C |
19: 29,694,229 (GRCm39) |
M1755V |
probably benign |
Het |
| Capns1 |
A |
G |
7: 29,891,765 (GRCm39) |
L124P |
probably damaging |
Het |
| Carmil1 |
A |
G |
13: 24,325,656 (GRCm39) |
S225P |
probably damaging |
Het |
| Cars2 |
C |
T |
8: 11,580,299 (GRCm39) |
A247T |
possibly damaging |
Het |
| Cd46 |
A |
G |
1: 194,744,721 (GRCm39) |
I339T |
probably benign |
Het |
| Ceacam14 |
C |
A |
7: 17,548,153 (GRCm39) |
T81N |
probably benign |
Het |
| Ceacam16 |
G |
A |
7: 19,595,066 (GRCm39) |
P4L |
probably benign |
Het |
| Chek1 |
C |
A |
9: 36,635,279 (GRCm39) |
V35F |
probably damaging |
Het |
| Cntnap5c |
A |
T |
17: 58,362,666 (GRCm39) |
I340L |
possibly damaging |
Het |
| Col2a1 |
C |
A |
15: 97,885,461 (GRCm39) |
A461S |
unknown |
Het |
| Comtd1 |
T |
C |
14: 21,898,340 (GRCm39) |
E27G |
possibly damaging |
Het |
| Cyp2a12 |
A |
G |
7: 26,732,042 (GRCm39) |
N261S |
probably benign |
Het |
| Dclk1 |
A |
G |
3: 55,154,633 (GRCm39) |
Y21C |
probably damaging |
Het |
| Dis3l |
T |
A |
9: 64,214,545 (GRCm39) |
N981I |
probably benign |
Het |
| Dlg5 |
A |
T |
14: 24,187,225 (GRCm39) |
I1819N |
probably damaging |
Het |
| Elp1 |
T |
A |
4: 56,779,636 (GRCm39) |
|
probably null |
Het |
| Enpep |
T |
C |
3: 129,074,231 (GRCm39) |
N772S |
probably damaging |
Het |
| Erich1 |
T |
C |
8: 14,128,773 (GRCm39) |
T56A |
probably benign |
Het |
| Ermp1 |
T |
C |
19: 29,614,798 (GRCm39) |
|
probably null |
Het |
| Etl4 |
A |
G |
2: 20,803,545 (GRCm39) |
E807G |
probably benign |
Het |
| Fat4 |
A |
T |
3: 39,037,544 (GRCm39) |
Y3732F |
probably damaging |
Het |
| Fbxw18 |
T |
G |
9: 109,522,438 (GRCm39) |
T144P |
probably damaging |
Het |
| Flywch1 |
A |
T |
17: 23,974,624 (GRCm39) |
I672K |
probably benign |
Het |
| Foxk2 |
C |
A |
11: 121,151,213 (GRCm39) |
A86E |
probably benign |
Het |
| Garem2 |
T |
C |
5: 30,313,297 (GRCm39) |
S54P |
probably damaging |
Het |
| Gda |
A |
G |
19: 21,374,869 (GRCm39) |
|
probably null |
Het |
| Gna15 |
T |
C |
10: 81,338,738 (GRCm39) |
Y367C |
probably damaging |
Het |
| Golga3 |
A |
G |
5: 110,335,856 (GRCm39) |
|
probably null |
Het |
| Greb1 |
T |
C |
12: 16,749,533 (GRCm39) |
S1098G |
probably damaging |
Het |
| Hook3 |
C |
A |
8: 26,560,225 (GRCm39) |
L333F |
probably damaging |
Het |
| Il6 |
C |
T |
5: 30,218,502 (GRCm39) |
Q33* |
probably null |
Het |
| Iqgap1 |
T |
C |
7: 80,401,701 (GRCm39) |
E468G |
probably benign |
Het |
| Iqgap1 |
A |
G |
7: 80,409,651 (GRCm39) |
I228T |
possibly damaging |
Het |
| Kat6b |
A |
T |
14: 21,718,735 (GRCm39) |
H1138L |
probably benign |
Het |
| Kcnab1 |
A |
T |
3: 65,278,861 (GRCm39) |
I371F |
probably damaging |
Het |
| Kcnj10 |
A |
T |
1: 172,197,455 (GRCm39) |
Y323F |
possibly damaging |
Het |
| Klk1b5 |
T |
C |
7: 43,869,322 (GRCm39) |
|
probably null |
Het |
| Lmo7 |
A |
G |
14: 102,157,951 (GRCm39) |
|
probably benign |
Het |
| Loxhd1 |
A |
T |
18: 77,443,862 (GRCm39) |
T277S |
possibly damaging |
Het |
| Lrp5 |
A |
T |
19: 3,664,339 (GRCm39) |
M796K |
probably benign |
Het |
| Med15 |
A |
T |
16: 17,503,315 (GRCm39) |
|
probably null |
Het |
| Mfn1 |
T |
A |
3: 32,596,975 (GRCm39) |
H144Q |
probably damaging |
Het |
| Mmp25 |
T |
A |
17: 23,850,048 (GRCm39) |
Y504F |
probably damaging |
Het |
| Nmi |
T |
C |
2: 51,842,555 (GRCm39) |
E179G |
probably damaging |
Het |
| Nrxn2 |
T |
C |
19: 6,554,944 (GRCm39) |
I1141T |
probably damaging |
Het |
| Olah |
T |
C |
2: 3,366,306 (GRCm39) |
S9G |
probably benign |
Het |
| Or1m1 |
T |
C |
9: 18,666,391 (GRCm39) |
D180G |
probably damaging |
Het |
| Or4c106 |
C |
A |
2: 88,683,128 (GRCm39) |
P278H |
probably damaging |
Het |
| Or5b120 |
T |
G |
19: 13,479,852 (GRCm39) |
I48M |
probably damaging |
Het |
| Or8b49 |
G |
T |
9: 38,505,707 (GRCm39) |
L63F |
probably damaging |
Het |
| Or8k22 |
A |
C |
2: 86,162,872 (GRCm39) |
F276C |
probably damaging |
Het |
| Otog |
T |
A |
7: 45,952,328 (GRCm39) |
C2591S |
probably damaging |
Het |
| Pdgfrb |
G |
T |
18: 61,205,828 (GRCm39) |
V605F |
probably damaging |
Het |
| Pik3cb |
T |
A |
9: 98,983,297 (GRCm39) |
K104* |
probably null |
Het |
| Plb1 |
T |
A |
5: 32,471,433 (GRCm39) |
I580N |
probably damaging |
Het |
| Plekha2 |
T |
C |
8: 25,578,413 (GRCm39) |
Y29C |
probably damaging |
Het |
| Plekha7 |
T |
A |
7: 115,775,002 (GRCm39) |
Y213F |
probably damaging |
Het |
| Plin5 |
T |
C |
17: 56,423,836 (GRCm39) |
D33G |
probably benign |
Het |
| Pnpla2 |
C |
A |
7: 141,039,132 (GRCm39) |
Q371K |
probably damaging |
Het |
| Ppm1n |
A |
G |
7: 19,012,110 (GRCm39) |
Y348H |
probably damaging |
Het |
| Ppp2r1b |
T |
A |
9: 50,777,854 (GRCm39) |
D266E |
probably damaging |
Het |
| Prss23 |
A |
G |
7: 89,159,119 (GRCm39) |
S317P |
probably damaging |
Het |
| Prss33 |
C |
T |
17: 24,053,817 (GRCm39) |
V87M |
probably damaging |
Het |
| Ptpn12 |
C |
A |
5: 21,207,466 (GRCm39) |
Q297H |
probably damaging |
Het |
| Pum1 |
G |
T |
4: 130,478,802 (GRCm39) |
A571S |
probably damaging |
Het |
| Rexo1 |
G |
T |
10: 80,379,943 (GRCm39) |
C13* |
probably null |
Het |
| Rhpn1 |
A |
T |
15: 75,576,243 (GRCm39) |
M1L |
probably null |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Ripk2 |
A |
G |
4: 16,132,775 (GRCm39) |
|
probably null |
Het |
| Rps6kc1 |
T |
C |
1: 190,530,920 (GRCm39) |
Y937C |
probably damaging |
Het |
| Rrbp1 |
A |
G |
2: 143,796,118 (GRCm39) |
L1200P |
possibly damaging |
Het |
| Ryr2 |
A |
G |
13: 11,592,759 (GRCm39) |
I4665T |
possibly damaging |
Het |
| Sbno1 |
C |
A |
5: 124,516,606 (GRCm39) |
V1256F |
probably benign |
Het |
| Senp5 |
T |
C |
16: 31,787,692 (GRCm39) |
I644V |
probably damaging |
Het |
| Serpinb9e |
T |
A |
13: 33,436,961 (GRCm39) |
F94I |
probably damaging |
Het |
| Sidt2 |
T |
C |
9: 45,856,638 (GRCm39) |
D477G |
probably damaging |
Het |
| Slc30a5 |
A |
T |
13: 100,940,457 (GRCm39) |
H619Q |
probably damaging |
Het |
| Slmap |
A |
G |
14: 26,139,402 (GRCm39) |
Y771H |
probably damaging |
Het |
| Sorl1 |
T |
C |
9: 41,895,788 (GRCm39) |
H1789R |
probably benign |
Het |
| Sp2 |
T |
C |
11: 96,852,834 (GRCm39) |
D30G |
possibly damaging |
Het |
| Stk33 |
T |
A |
7: 108,940,527 (GRCm39) |
N61I |
probably benign |
Het |
| Stxbp1 |
T |
A |
2: 32,692,868 (GRCm39) |
I383F |
probably damaging |
Het |
| Tbcd |
A |
G |
11: 121,494,457 (GRCm39) |
Q1006R |
possibly damaging |
Het |
| Tln2 |
T |
C |
9: 67,209,842 (GRCm39) |
T432A |
probably damaging |
Het |
| Tnfrsf21 |
A |
G |
17: 43,398,763 (GRCm39) |
D623G |
probably damaging |
Het |
| Trib2 |
A |
G |
12: 15,843,830 (GRCm39) |
F271L |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,810,477 (GRCm39) |
V17A |
probably benign |
Het |
| Ubqlnl |
A |
T |
7: 103,797,890 (GRCm39) |
C536S |
probably benign |
Het |
| Vmn1r230 |
T |
A |
17: 21,067,063 (GRCm39) |
M84K |
probably damaging |
Het |
| Vmn2r97 |
A |
T |
17: 19,167,584 (GRCm39) |
R613* |
probably null |
Het |
| Yeats2 |
T |
A |
16: 19,972,916 (GRCm39) |
D23E |
probably damaging |
Het |
| Zan |
T |
A |
5: 137,434,662 (GRCm39) |
I2214F |
unknown |
Het |
| Zbtb40 |
T |
C |
4: 136,718,946 (GRCm39) |
D917G |
probably damaging |
Het |
| Zcchc2 |
C |
A |
1: 105,949,453 (GRCm39) |
|
probably null |
Het |
| Zdhhc23 |
G |
T |
16: 43,794,282 (GRCm39) |
Q131K |
probably benign |
Het |
| Zfp345 |
T |
C |
2: 150,314,578 (GRCm39) |
T320A |
probably benign |
Het |
| Zfp532 |
A |
G |
18: 65,757,998 (GRCm39) |
T644A |
possibly damaging |
Het |
|
| Other mutations in Sned1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00785:Sned1
|
APN |
1 |
93,201,891 (GRCm39) |
splice site |
probably benign |
|
|
IGL00955:Sned1
|
APN |
1 |
93,202,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01367:Sned1
|
APN |
1 |
93,210,936 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02116:Sned1
|
APN |
1 |
93,209,447 (GRCm39) |
nonsense |
probably null |
|
|
IGL02195:Sned1
|
APN |
1 |
93,201,882 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02390:Sned1
|
APN |
1 |
93,189,386 (GRCm39) |
missense |
probably benign |
|
|
IGL02423:Sned1
|
APN |
1 |
93,211,322 (GRCm39) |
missense |
probably benign |
|
|
IGL02451:Sned1
|
APN |
1 |
93,163,930 (GRCm39) |
splice site |
probably benign |
|
|
IGL02567:Sned1
|
APN |
1 |
93,202,069 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03184:Sned1
|
APN |
1 |
93,202,390 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03328:Sned1
|
APN |
1 |
93,217,089 (GRCm39) |
missense |
probably benign |
|
|
Bulger
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
farina
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Millet
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
triticale
|
UTSW |
1 |
93,281,654 (GRCm39) |
missense |
|
|
|
R0257:Sned1
|
UTSW |
1 |
93,192,819 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R0372:Sned1
|
UTSW |
1 |
93,213,673 (GRCm39) |
splice site |
probably benign |
|
|
R0525:Sned1
|
UTSW |
1 |
93,199,696 (GRCm39) |
splice site |
probably null |
|
|
R0727:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0759:Sned1
|
UTSW |
1 |
93,200,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0965:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0968:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0969:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1006:Sned1
|
UTSW |
1 |
93,184,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1068:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1069:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1070:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1112:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1113:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1114:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1115:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1118:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1119:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1144:Sned1
|
UTSW |
1 |
93,208,298 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1228:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1230:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1231:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1340:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1382:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1383:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1394:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1395:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1397:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1414:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1430:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1432:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1473:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1503:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1563:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1565:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1689:Sned1
|
UTSW |
1 |
93,211,094 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1695:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1734:Sned1
|
UTSW |
1 |
93,187,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1764:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1767:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1896:Sned1
|
UTSW |
1 |
93,192,769 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1916:Sned1
|
UTSW |
1 |
93,201,884 (GRCm39) |
missense |
probably null |
1.00 |
|
R1945:Sned1
|
UTSW |
1 |
93,198,960 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1972:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1973:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2144:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2273:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2274:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2275:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2340:Sned1
|
UTSW |
1 |
93,184,174 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3237:Sned1
|
UTSW |
1 |
93,186,725 (GRCm39) |
missense |
probably benign |
0.21 |
|
R3747:Sned1
|
UTSW |
1 |
93,189,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3879:Sned1
|
UTSW |
1 |
93,192,752 (GRCm39) |
splice site |
probably benign |
|
|
R4281:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4282:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4356:Sned1
|
UTSW |
1 |
93,193,113 (GRCm39) |
splice site |
probably null |
|
|
R4358:Sned1
|
UTSW |
1 |
93,202,381 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4677:Sned1
|
UTSW |
1 |
93,224,019 (GRCm39) |
unclassified |
probably benign |
|
|
R5291:Sned1
|
UTSW |
1 |
93,223,446 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5340:Sned1
|
UTSW |
1 |
93,210,479 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5542:Sned1
|
UTSW |
1 |
93,199,324 (GRCm39) |
missense |
probably benign |
|
|
R5582:Sned1
|
UTSW |
1 |
93,210,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5874:Sned1
|
UTSW |
1 |
93,193,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6159:Sned1
|
UTSW |
1 |
93,210,659 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6175:Sned1
|
UTSW |
1 |
93,203,196 (GRCm39) |
splice site |
probably null |
|
|
R6445:Sned1
|
UTSW |
1 |
93,211,318 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6631:Sned1
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Sned1
|
UTSW |
1 |
93,212,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7035:Sned1
|
UTSW |
1 |
93,189,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7047:Sned1
|
UTSW |
1 |
93,213,540 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7347:Sned1
|
UTSW |
1 |
93,209,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Sned1
|
UTSW |
1 |
93,217,080 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7581:Sned1
|
UTSW |
1 |
93,184,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7679:Sned1
|
UTSW |
1 |
93,163,760 (GRCm39) |
missense |
unknown |
|
|
R7899:Sned1
|
UTSW |
1 |
93,201,804 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8093:Sned1
|
UTSW |
1 |
93,202,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8124:Sned1
|
UTSW |
1 |
93,210,711 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8489:Sned1
|
UTSW |
1 |
93,210,978 (GRCm39) |
nonsense |
probably null |
|
|
R9012:Sned1
|
UTSW |
1 |
93,212,320 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9290:Sned1
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
R9560:Sned1
|
UTSW |
1 |
93,202,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9775:Sned1
|
UTSW |
1 |
93,199,604 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0025:Sned1
|
UTSW |
1 |
93,189,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sned1
|
UTSW |
1 |
93,186,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Sned1
|
UTSW |
1 |
93,213,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACTCGCCTCAGCACACATG -3'
(R):5'- CTGCAGACACTGATTCCCTC -3'
Sequencing Primer
(F):5'- GCACACATGAAAACTGGGTC -3'
(R):5'- TGATTGAGAATGGCCCTCAC -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation