Incidental Mutation 'R2155:Myom2'
| ID |
234725 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| MMRRC Submission |
040158-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.148)
|
| Stock # |
R2155 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 15134555 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 453
(Y453N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000033842
AA Change: Y453N
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
AA Change: Y453N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610318N02Rik |
A |
G |
16: 16,939,260 (GRCm39) |
L41P |
probably damaging |
Het |
| Aff4 |
C |
T |
11: 53,290,446 (GRCm39) |
L469F |
probably damaging |
Het |
| AI182371 |
G |
A |
2: 34,975,366 (GRCm39) |
H288Y |
probably benign |
Het |
| AK157302 |
A |
T |
13: 21,679,827 (GRCm39) |
K118* |
probably null |
Het |
| Arhgef2 |
G |
A |
3: 88,543,351 (GRCm39) |
R454Q |
probably damaging |
Het |
| Asb17 |
C |
T |
3: 153,550,322 (GRCm39) |
T118M |
probably damaging |
Het |
| Atp7b |
A |
G |
8: 22,503,600 (GRCm39) |
V718A |
possibly damaging |
Het |
| Cdca2 |
A |
G |
14: 67,952,287 (GRCm39) |
L28S |
probably damaging |
Het |
| Cdh20 |
G |
T |
1: 109,976,594 (GRCm39) |
L86F |
probably damaging |
Het |
| Cela2a |
A |
T |
4: 141,545,350 (GRCm39) |
|
probably null |
Het |
| Cers3 |
T |
A |
7: 66,433,162 (GRCm39) |
Y160N |
probably damaging |
Het |
| Chmp2b |
A |
G |
16: 65,343,877 (GRCm39) |
V56A |
probably benign |
Het |
| Cryl1 |
A |
G |
14: 57,635,880 (GRCm39) |
V9A |
unknown |
Het |
| Dmbt1 |
A |
T |
7: 130,699,305 (GRCm39) |
H978L |
possibly damaging |
Het |
| Dnm1 |
C |
T |
2: 32,204,949 (GRCm39) |
V673M |
probably damaging |
Het |
| Dtx4 |
T |
A |
19: 12,462,646 (GRCm39) |
K378* |
probably null |
Het |
| Extl1 |
A |
T |
4: 134,090,491 (GRCm39) |
M328K |
possibly damaging |
Het |
| Fcgbp |
T |
C |
7: 27,806,628 (GRCm39) |
S2199P |
probably benign |
Het |
| Glis3 |
G |
T |
19: 28,508,702 (GRCm39) |
N427K |
probably benign |
Het |
| Hdac7 |
T |
C |
15: 97,691,944 (GRCm39) |
K810E |
probably benign |
Het |
| Hesx1 |
A |
G |
14: 26,723,434 (GRCm39) |
E88G |
probably benign |
Het |
| Hmcn2 |
A |
T |
2: 31,350,361 (GRCm39) |
Q5086L |
possibly damaging |
Het |
| Ier3 |
A |
G |
17: 36,133,101 (GRCm39) |
T128A |
probably benign |
Het |
| Igsf10 |
G |
T |
3: 59,239,101 (GRCm39) |
T360K |
probably damaging |
Het |
| Ilkap |
A |
C |
1: 91,312,345 (GRCm39) |
C2G |
possibly damaging |
Het |
| Itih1 |
A |
G |
14: 30,660,028 (GRCm39) |
F231S |
probably damaging |
Het |
| Jrkl |
A |
T |
9: 13,244,913 (GRCm39) |
Y249* |
probably null |
Het |
| Kat6a |
AGAGGAGGAGGAGGAGGAGGAGGAG |
AGAGGAGGAGGAGGAGGAGGAG |
8: 23,425,663 (GRCm39) |
|
probably benign |
Het |
| Katnal2 |
A |
T |
18: 77,098,637 (GRCm39) |
S184R |
probably benign |
Het |
| Kcnh5 |
T |
A |
12: 74,945,230 (GRCm39) |
|
probably null |
Het |
| Kcnj11 |
G |
T |
7: 45,748,781 (GRCm39) |
L181I |
probably damaging |
Het |
| Klhl2 |
T |
C |
8: 65,202,804 (GRCm39) |
T465A |
probably benign |
Het |
| Krt90 |
T |
A |
15: 101,471,046 (GRCm39) |
Y72F |
probably benign |
Het |
| Lig4 |
G |
A |
8: 10,022,766 (GRCm39) |
T338I |
probably benign |
Het |
| Lrrc37 |
T |
C |
11: 103,511,285 (GRCm39) |
T228A |
unknown |
Het |
| Magel2 |
T |
C |
7: 62,030,540 (GRCm39) |
V1148A |
unknown |
Het |
| Mak |
C |
A |
13: 41,186,020 (GRCm39) |
E549D |
probably benign |
Het |
| Marf1 |
G |
T |
16: 13,950,293 (GRCm39) |
S1001Y |
probably damaging |
Het |
| Mcoln1 |
G |
A |
8: 3,561,787 (GRCm39) |
V446I |
probably damaging |
Het |
| Meig1 |
T |
C |
2: 3,410,290 (GRCm39) |
N70S |
probably benign |
Het |
| Mfsd14a |
G |
A |
3: 116,441,479 (GRCm39) |
T108I |
probably damaging |
Het |
| Mocs1 |
G |
A |
17: 49,761,386 (GRCm39) |
M493I |
probably damaging |
Het |
| Mrpl11 |
C |
A |
19: 5,012,497 (GRCm39) |
A26E |
probably damaging |
Het |
| Myh6 |
A |
T |
14: 55,191,251 (GRCm39) |
D863E |
probably benign |
Het |
| Nhlh1 |
A |
G |
1: 171,881,524 (GRCm39) |
I114T |
probably damaging |
Het |
| Odr4 |
A |
G |
1: 150,258,086 (GRCm39) |
V183A |
possibly damaging |
Het |
| Or12j4 |
A |
C |
7: 140,046,504 (GRCm39) |
H130P |
probably benign |
Het |
| Or2y3 |
G |
T |
17: 38,393,071 (GRCm39) |
P266Q |
probably damaging |
Het |
| Or4k5 |
A |
T |
14: 50,386,154 (GRCm39) |
M59K |
probably damaging |
Het |
| Or5k17 |
G |
T |
16: 58,746,486 (GRCm39) |
F149L |
probably benign |
Het |
| Or5p80 |
C |
G |
7: 108,229,984 (GRCm39) |
P262A |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,764,309 (GRCm39) |
S976P |
probably benign |
Het |
| Pde3a |
G |
A |
6: 141,429,640 (GRCm39) |
E734K |
possibly damaging |
Het |
| Pdzd2 |
A |
T |
15: 12,375,879 (GRCm39) |
S1419T |
probably benign |
Het |
| Pdzd8 |
T |
A |
19: 59,288,853 (GRCm39) |
Y849F |
probably damaging |
Het |
| Phldb3 |
A |
G |
7: 24,312,070 (GRCm39) |
E128G |
probably damaging |
Het |
| Polg |
A |
G |
7: 79,111,468 (GRCm39) |
I261T |
possibly damaging |
Het |
| Ppp1r35 |
T |
C |
5: 137,778,267 (GRCm39) |
M254T |
probably benign |
Het |
| Ppp3ca |
G |
T |
3: 136,596,211 (GRCm39) |
R292M |
possibly damaging |
Het |
| Ptk7 |
T |
A |
17: 46,890,543 (GRCm39) |
T430S |
probably benign |
Het |
| Ptrh1 |
T |
A |
2: 32,667,040 (GRCm39) |
N144K |
possibly damaging |
Het |
| Rbfox1 |
A |
G |
16: 7,111,946 (GRCm39) |
T211A |
possibly damaging |
Het |
| Rbpjl |
A |
G |
2: 164,256,343 (GRCm39) |
D443G |
possibly damaging |
Het |
| Rcc1 |
A |
G |
4: 132,065,360 (GRCm39) |
|
probably null |
Het |
| Rimbp2 |
G |
T |
5: 128,865,229 (GRCm39) |
S706R |
probably damaging |
Het |
| Rsph10b |
G |
C |
5: 143,898,074 (GRCm39) |
E96D |
probably benign |
Het |
| Scn10a |
A |
T |
9: 119,438,514 (GRCm39) |
I1784K |
probably benign |
Het |
| Sfxn2 |
A |
G |
19: 46,579,985 (GRCm39) |
|
probably null |
Het |
| Slamf6 |
T |
A |
1: 171,765,575 (GRCm39) |
L233Q |
probably damaging |
Het |
| Slc17a5 |
A |
T |
9: 78,484,455 (GRCm39) |
Y102N |
probably damaging |
Het |
| Slc25a53 |
T |
C |
X: 135,884,216 (GRCm39) |
T42A |
probably damaging |
Het |
| Slco1a8 |
T |
C |
6: 141,926,670 (GRCm39) |
D552G |
probably damaging |
Het |
| Smg7 |
G |
A |
1: 152,716,064 (GRCm39) |
T1057I |
possibly damaging |
Het |
| Speer2 |
T |
A |
16: 69,657,485 (GRCm39) |
T53S |
possibly damaging |
Het |
| Srm |
A |
C |
4: 148,676,948 (GRCm39) |
I100L |
probably benign |
Het |
| Stoml3 |
A |
C |
3: 53,415,008 (GRCm39) |
N267H |
probably damaging |
Het |
| Thsd7a |
A |
C |
6: 12,379,632 (GRCm39) |
C931G |
probably damaging |
Het |
| Tlr11 |
A |
G |
14: 50,598,139 (GRCm39) |
I42V |
probably benign |
Het |
| Tmigd1 |
T |
C |
11: 76,800,999 (GRCm39) |
V162A |
probably benign |
Het |
| Tmx3 |
A |
G |
18: 90,528,505 (GRCm39) |
|
probably null |
Het |
| Topors |
T |
A |
4: 40,262,790 (GRCm39) |
R165W |
possibly damaging |
Het |
| Ttc17 |
A |
T |
2: 94,196,987 (GRCm39) |
S453R |
possibly damaging |
Het |
| Vmn1r49 |
G |
T |
6: 90,049,441 (GRCm39) |
T187N |
probably damaging |
Het |
| Zbtb49 |
A |
T |
5: 38,371,464 (GRCm39) |
V139E |
possibly damaging |
Het |
| Zfp11 |
T |
C |
5: 129,734,216 (GRCm39) |
H415R |
probably damaging |
Het |
| Zfp677 |
A |
T |
17: 21,617,970 (GRCm39) |
K342N |
probably benign |
Het |
| Zfp979 |
A |
C |
4: 147,697,915 (GRCm39) |
C265G |
possibly damaging |
Het |
| Zfpl1 |
T |
C |
19: 6,134,459 (GRCm39) |
R9G |
probably damaging |
Het |
| Zkscan8 |
A |
T |
13: 21,704,759 (GRCm39) |
C321* |
probably null |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0116:Myom2
|
UTSW |
8 |
15,167,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0463:Myom2
|
UTSW |
8 |
15,154,123 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0544:Myom2
|
UTSW |
8 |
15,119,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Myom2
|
UTSW |
8 |
15,115,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2018:Myom2
|
UTSW |
8 |
15,181,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6248:Myom2
|
UTSW |
8 |
15,148,472 (GRCm39) |
splice site |
probably null |
|
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8094:Myom2
|
UTSW |
8 |
15,119,418 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAATGGCTCCTCATGGTGACTG -3'
(R):5'- CGGGATGCCATACTTAAGGC -3'
Sequencing Primer
(F):5'- CTCATGGTGACTGCTCTCTATGAG -3'
(R):5'- GGATGCCATACTTAAGGCTCACATG -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation