Incidental Mutation 'R0200:Myo1c'
| ID |
23583 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo1c
|
| Ensembl Gene |
ENSMUSG00000017774 |
| Gene Name |
myosin IC |
| Synonyms |
myr2, mm1beta, C80397, myosin-Ibeta |
| MMRRC Submission |
038457-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.684)
|
| Stock # |
R0200 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
75541330-75564736 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 75563008 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 997
(D997E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099562
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069057]
[ENSMUST00000102504]
[ENSMUST00000102505]
[ENSMUST00000108431]
|
| AlphaFold |
Q9WTI7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000069057
AA Change: D997E
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000070388
Gene: ENSMUSG00000017774
AA Change: D997E
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
5 |
697 |
N/A |
SMART |
|
IQ
|
698 |
720 |
3.85e-3 |
SMART |
|
IQ
|
721 |
743 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
751 |
780 |
5e-9 |
BLAST |
|
low complexity region
|
804 |
815 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
838 |
1024 |
1.9e-41 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102504
AA Change: D997E
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000099562
Gene: ENSMUSG00000017774
AA Change: D997E
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
5 |
697 |
N/A |
SMART |
|
IQ
|
698 |
720 |
3.85e-3 |
SMART |
|
IQ
|
721 |
743 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
751 |
780 |
5e-9 |
BLAST |
|
low complexity region
|
804 |
815 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
838 |
1024 |
1.9e-41 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102505
AA Change: D1032E
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000099563
Gene: ENSMUSG00000017774
AA Change: D1032E
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
40 |
732 |
N/A |
SMART |
|
IQ
|
733 |
755 |
3.85e-3 |
SMART |
|
IQ
|
756 |
778 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
786 |
815 |
6e-9 |
BLAST |
|
low complexity region
|
839 |
850 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
874 |
1052 |
2.9e-29 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108431
AA Change: D1013E
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000104069
Gene: ENSMUSG00000017774
AA Change: D1013E
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
21 |
713 |
N/A |
SMART |
|
IQ
|
714 |
736 |
3.85e-3 |
SMART |
|
IQ
|
737 |
759 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
767 |
796 |
5e-9 |
BLAST |
|
low complexity region
|
820 |
831 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
854 |
1040 |
3.3e-41 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123064
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146419
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151174
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155027
|
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.8%
- 10x: 94.7%
- 20x: 86.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The protein functions in intracellular vesicle transport to the plasma membrane. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-in (Y61G) mutation that sensitizes to N6-modified ADP analogs display altered fast adaption in vestibular hair cells. Mice homozygous for a nuclear isoform-specifc knock-out allele exhibit minor changes in bone marrow density and red blood cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aatf |
T |
C |
11: 84,336,502 (GRCm39) |
K466E |
probably damaging |
Het |
| Abcc3 |
T |
C |
11: 94,245,900 (GRCm39) |
D1245G |
probably damaging |
Het |
| Adam12 |
T |
C |
7: 133,576,145 (GRCm39) |
|
probably null |
Het |
| Akap11 |
A |
G |
14: 78,748,193 (GRCm39) |
V1398A |
probably benign |
Het |
| Ank1 |
T |
G |
8: 23,586,828 (GRCm39) |
L461R |
probably damaging |
Het |
| Ankfn1 |
T |
C |
11: 89,332,792 (GRCm39) |
S402G |
possibly damaging |
Het |
| Arhgef40 |
A |
C |
14: 52,234,431 (GRCm39) |
E911D |
probably damaging |
Het |
| Atp2b1 |
C |
T |
10: 98,815,676 (GRCm39) |
Q107* |
probably null |
Het |
| Cacng3 |
T |
A |
7: 122,271,008 (GRCm39) |
C4* |
probably null |
Het |
| Cds1 |
G |
A |
5: 101,962,299 (GRCm39) |
V305M |
probably damaging |
Het |
| Cecr2 |
T |
G |
6: 120,738,758 (GRCm39) |
F1162V |
probably damaging |
Het |
| Cfap70 |
A |
T |
14: 20,498,631 (GRCm39) |
Y19N |
probably damaging |
Het |
| Chrm5 |
A |
G |
2: 112,311,065 (GRCm39) |
V17A |
probably benign |
Het |
| Col20a1 |
T |
C |
2: 180,642,231 (GRCm39) |
I714T |
probably damaging |
Het |
| Cpeb2 |
T |
A |
5: 43,419,119 (GRCm39) |
M156K |
possibly damaging |
Het |
| Cstdc6 |
T |
C |
16: 36,143,386 (GRCm39) |
|
probably null |
Het |
| Defb25 |
C |
A |
2: 152,464,332 (GRCm39) |
V71L |
probably benign |
Het |
| Dhx35 |
A |
T |
2: 158,671,543 (GRCm39) |
M325L |
probably benign |
Het |
| Dhx57 |
A |
T |
17: 80,558,902 (GRCm39) |
L1019H |
probably damaging |
Het |
| Dnah6 |
T |
A |
6: 73,046,403 (GRCm39) |
D3195V |
probably damaging |
Het |
| Dph5 |
A |
G |
3: 115,722,352 (GRCm39) |
S277G |
probably benign |
Het |
| Dpm1 |
C |
A |
2: 168,065,075 (GRCm39) |
|
probably null |
Het |
| Dsg1a |
A |
T |
18: 20,473,995 (GRCm39) |
M1023L |
probably benign |
Het |
| Egf |
A |
G |
3: 129,499,882 (GRCm39) |
Y252H |
probably benign |
Het |
| Egf |
A |
G |
3: 129,531,198 (GRCm39) |
S126P |
probably damaging |
Het |
| Enam |
T |
C |
5: 88,640,886 (GRCm39) |
W183R |
possibly damaging |
Het |
| Foxn1 |
T |
C |
11: 78,251,866 (GRCm39) |
Y455C |
probably damaging |
Het |
| Iars1 |
A |
T |
13: 49,879,678 (GRCm39) |
D983V |
possibly damaging |
Het |
| Ikzf4 |
C |
A |
10: 128,470,545 (GRCm39) |
G325V |
probably damaging |
Het |
| Il1rl1 |
T |
A |
1: 40,480,463 (GRCm39) |
W31R |
possibly damaging |
Het |
| Ip6k3 |
C |
T |
17: 27,363,999 (GRCm39) |
D350N |
probably damaging |
Het |
| Irgc |
T |
C |
7: 24,131,431 (GRCm39) |
D462G |
probably benign |
Het |
| Itprid1 |
T |
C |
6: 55,874,941 (GRCm39) |
L297P |
probably benign |
Het |
| Jph3 |
A |
G |
8: 122,511,572 (GRCm39) |
E520G |
probably benign |
Het |
| Kcna2 |
T |
A |
3: 107,012,476 (GRCm39) |
D352E |
probably benign |
Het |
| Klk4 |
T |
A |
7: 43,534,785 (GRCm39) |
I248N |
probably damaging |
Het |
| Krtap16-1 |
T |
C |
11: 99,876,123 (GRCm39) |
Y427C |
probably damaging |
Het |
| Lgr4 |
A |
G |
2: 109,801,035 (GRCm39) |
|
probably null |
Het |
| Lhpp |
C |
T |
7: 132,212,406 (GRCm39) |
|
probably benign |
Het |
| Lypd3 |
T |
A |
7: 24,339,656 (GRCm39) |
V241D |
probably damaging |
Het |
| Lyz2 |
T |
A |
10: 117,116,678 (GRCm39) |
N57Y |
possibly damaging |
Het |
| Man1a |
A |
G |
10: 53,950,594 (GRCm39) |
V176A |
probably damaging |
Het |
| Mcm4 |
G |
A |
16: 15,447,503 (GRCm39) |
T487I |
probably benign |
Het |
| Mettl21c |
T |
A |
1: 44,052,814 (GRCm39) |
I68F |
probably damaging |
Het |
| Miip |
T |
A |
4: 147,946,720 (GRCm39) |
T313S |
probably damaging |
Het |
| Minar2 |
A |
G |
18: 59,195,531 (GRCm39) |
|
probably null |
Het |
| Mog |
A |
T |
17: 37,323,311 (GRCm39) |
I209K |
probably damaging |
Het |
| Npc1 |
T |
C |
18: 12,352,261 (GRCm39) |
Y146C |
probably damaging |
Het |
| Nploc4 |
A |
G |
11: 120,304,507 (GRCm39) |
L238P |
probably damaging |
Het |
| Opa1 |
A |
G |
16: 29,432,947 (GRCm39) |
N544S |
probably benign |
Het |
| Or2j6 |
T |
C |
7: 139,980,788 (GRCm39) |
Y57C |
probably damaging |
Het |
| Or2v1 |
T |
A |
11: 49,025,874 (GRCm39) |
M285K |
probably damaging |
Het |
| Or6k6 |
T |
C |
1: 173,945,078 (GRCm39) |
H168R |
probably benign |
Het |
| Pam |
C |
T |
1: 97,822,126 (GRCm39) |
|
probably null |
Het |
| Pdgfra |
T |
C |
5: 75,324,438 (GRCm39) |
Y98H |
probably damaging |
Het |
| Plcz1 |
C |
T |
6: 139,936,459 (GRCm39) |
R590H |
probably damaging |
Het |
| Plxdc1 |
T |
C |
11: 97,824,838 (GRCm39) |
Y339C |
probably damaging |
Het |
| Plxna1 |
T |
C |
6: 89,300,575 (GRCm39) |
N1583S |
probably damaging |
Het |
| Plxna4 |
C |
T |
6: 32,174,023 (GRCm39) |
V1191M |
probably damaging |
Het |
| Polk |
T |
A |
13: 96,633,330 (GRCm39) |
N238Y |
probably benign |
Het |
| Ptprq |
T |
C |
10: 107,521,018 (GRCm39) |
N718S |
probably benign |
Het |
| Rsrc1 |
A |
T |
3: 67,088,194 (GRCm39) |
H176L |
probably damaging |
Het |
| Sbno1 |
T |
C |
5: 124,522,604 (GRCm39) |
D1072G |
probably damaging |
Het |
| Scmh1 |
A |
G |
4: 120,341,028 (GRCm39) |
K238R |
probably damaging |
Het |
| Senp7 |
A |
G |
16: 55,944,236 (GRCm39) |
T187A |
possibly damaging |
Het |
| Slc12a4 |
T |
C |
8: 106,678,249 (GRCm39) |
R315G |
probably benign |
Het |
| Slc16a10 |
A |
G |
10: 39,916,612 (GRCm39) |
V430A |
probably benign |
Het |
| Slc26a7 |
T |
C |
4: 14,621,317 (GRCm39) |
D23G |
probably benign |
Het |
| Slc28a2b |
T |
A |
2: 122,357,928 (GRCm39) |
*661R |
probably null |
Het |
| Slc7a7 |
A |
G |
14: 54,615,259 (GRCm39) |
L246P |
probably damaging |
Het |
| Spata7 |
T |
A |
12: 98,629,428 (GRCm39) |
S332T |
probably benign |
Het |
| Spsb1 |
A |
G |
4: 149,982,673 (GRCm39) |
*274R |
probably null |
Het |
| Sspo |
T |
G |
6: 48,463,349 (GRCm39) |
V3767G |
probably null |
Het |
| Syt10 |
C |
A |
15: 89,711,144 (GRCm39) |
A130S |
probably benign |
Het |
| Tgm6 |
T |
A |
2: 129,994,865 (GRCm39) |
|
probably null |
Het |
| Them7 |
A |
C |
2: 105,128,262 (GRCm39) |
N81T |
probably damaging |
Het |
| Tinag |
C |
A |
9: 76,859,217 (GRCm39) |
A464S |
probably damaging |
Het |
| Tmem217 |
T |
G |
17: 29,745,284 (GRCm39) |
I149L |
probably benign |
Het |
| Trp53rkb |
T |
G |
2: 166,637,603 (GRCm39) |
D186E |
probably damaging |
Het |
| Vmn1r20 |
T |
C |
6: 57,409,084 (GRCm39) |
Y137H |
probably damaging |
Het |
| Vmn1r60 |
T |
A |
7: 5,547,379 (GRCm39) |
L240F |
probably benign |
Het |
| Vmn1r64 |
A |
G |
7: 5,886,817 (GRCm39) |
M242T |
probably benign |
Het |
| Xkr4 |
T |
C |
1: 3,740,886 (GRCm39) |
N229S |
probably benign |
Het |
| Zcchc2 |
T |
A |
1: 105,931,853 (GRCm39) |
L352M |
probably damaging |
Het |
| Zfp217 |
C |
T |
2: 169,957,382 (GRCm39) |
A539T |
probably benign |
Het |
| Zfp638 |
T |
C |
6: 83,944,336 (GRCm39) |
L1018P |
probably damaging |
Het |
|
| Other mutations in Myo1c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01346:Myo1c
|
APN |
11 |
75,563,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02054:Myo1c
|
APN |
11 |
75,551,962 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02115:Myo1c
|
APN |
11 |
75,552,417 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02375:Myo1c
|
APN |
11 |
75,552,400 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02878:Myo1c
|
APN |
11 |
75,559,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03008:Myo1c
|
APN |
11 |
75,549,240 (GRCm39) |
missense |
probably benign |
0.13 |
|
Sweeper
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R0070:Myo1c
|
UTSW |
11 |
75,551,076 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0070:Myo1c
|
UTSW |
11 |
75,551,076 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0138:Myo1c
|
UTSW |
11 |
75,551,827 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0227:Myo1c
|
UTSW |
11 |
75,549,520 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0257:Myo1c
|
UTSW |
11 |
75,556,342 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0513:Myo1c
|
UTSW |
11 |
75,556,657 (GRCm39) |
splice site |
probably null |
|
|
R0587:Myo1c
|
UTSW |
11 |
75,548,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0667:Myo1c
|
UTSW |
11 |
75,559,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo1c
|
UTSW |
11 |
75,560,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo1c
|
UTSW |
11 |
75,560,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1793:Myo1c
|
UTSW |
11 |
75,548,415 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1922:Myo1c
|
UTSW |
11 |
75,559,055 (GRCm39) |
missense |
probably benign |
|
|
R2000:Myo1c
|
UTSW |
11 |
75,561,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3983:Myo1c
|
UTSW |
11 |
75,552,325 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4583:Myo1c
|
UTSW |
11 |
75,562,688 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4599:Myo1c
|
UTSW |
11 |
75,559,019 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4671:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4682:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4708:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4709:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4742:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4770:Myo1c
|
UTSW |
11 |
75,551,139 (GRCm39) |
nonsense |
probably null |
|
|
R4888:Myo1c
|
UTSW |
11 |
75,560,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Myo1c
|
UTSW |
11 |
75,547,135 (GRCm39) |
start codon destroyed |
probably null |
|
|
R4934:Myo1c
|
UTSW |
11 |
75,562,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4971:Myo1c
|
UTSW |
11 |
75,562,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5319:Myo1c
|
UTSW |
11 |
75,552,852 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5589:Myo1c
|
UTSW |
11 |
75,548,414 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5624:Myo1c
|
UTSW |
11 |
75,553,461 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5756:Myo1c
|
UTSW |
11 |
75,549,240 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5959:Myo1c
|
UTSW |
11 |
75,548,345 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6160:Myo1c
|
UTSW |
11 |
75,541,568 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6559:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6568:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6569:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6574:Myo1c
|
UTSW |
11 |
75,547,124 (GRCm39) |
start gained |
probably benign |
|
|
R6579:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6580:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6583:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6640:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6642:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6643:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6679:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6680:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6687:Myo1c
|
UTSW |
11 |
75,563,027 (GRCm39) |
missense |
probably benign |
|
|
R6695:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6696:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6700:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6712:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6713:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6715:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7081:Myo1c
|
UTSW |
11 |
75,551,789 (GRCm39) |
missense |
probably benign |
|
|
R7265:Myo1c
|
UTSW |
11 |
75,560,616 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7397:Myo1c
|
UTSW |
11 |
75,562,068 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7586:Myo1c
|
UTSW |
11 |
75,548,345 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7714:Myo1c
|
UTSW |
11 |
75,549,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Myo1c
|
UTSW |
11 |
75,546,942 (GRCm39) |
unclassified |
probably benign |
|
|
R8341:Myo1c
|
UTSW |
11 |
75,562,253 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8466:Myo1c
|
UTSW |
11 |
75,549,213 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8771:Myo1c
|
UTSW |
11 |
75,556,709 (GRCm39) |
missense |
probably benign |
|
|
R8829:Myo1c
|
UTSW |
11 |
75,561,072 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8832:Myo1c
|
UTSW |
11 |
75,561,072 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9243:Myo1c
|
UTSW |
11 |
75,541,437 (GRCm39) |
unclassified |
probably benign |
|
|
R9489:Myo1c
|
UTSW |
11 |
75,559,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9605:Myo1c
|
UTSW |
11 |
75,559,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9744:Myo1c
|
UTSW |
11 |
75,562,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9782:Myo1c
|
UTSW |
11 |
75,549,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGACCGCGTGAACAATATCAAC -3'
(R):5'- AATACCTGCTTGCCAGAGTGAACC -3'
Sequencing Primer
(F):5'- TATCAACATCAACCAGGGCAGG -3'
(R):5'- CACCATAGGGGTCCAAGC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation