Incidental Mutation 'R0973:Ift172'
| ID |
236724 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ift172
|
| Ensembl Gene |
ENSMUSG00000038564 |
| Gene Name |
intraflagellar transport 172 |
| Synonyms |
wim |
| MMRRC Submission |
039102-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0973 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
31253277-31291116 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 31265355 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Histidine
at position 917
(R917H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041565]
|
| AlphaFold |
Q6VH22 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041565
AA Change: R917H
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000049335
Gene: ENSMUSG00000038564
AA Change: R917H
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
44 |
6e-3 |
SMART |
|
WD40
|
55 |
94 |
2.22e0 |
SMART |
|
WD40
|
102 |
139 |
1.23e2 |
SMART |
|
WD40
|
141 |
180 |
4.6e0 |
SMART |
|
WD40
|
186 |
223 |
3.3e1 |
SMART |
|
WD40
|
225 |
267 |
4.42e1 |
SMART |
|
WD40
|
279 |
314 |
1.03e1 |
SMART |
|
Blast:WD40
|
516 |
550 |
5e-13 |
BLAST |
|
low complexity region
|
573 |
588 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
625 |
1026 |
1.7e-10 |
PROSPERO |
|
Blast:TPR
|
1029 |
1062 |
2e-13 |
BLAST |
|
low complexity region
|
1077 |
1091 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1101 |
1498 |
1.7e-10 |
PROSPERO |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200936
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201057
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201953
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202585
|
| SMART Domains |
Protein: ENSMUSP00000144216
Gene: ENSMUSG00000038564
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:WD40
|
46 |
78 |
2e-11 |
BLAST |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.6%
- 20x: 96.0%
|
| Validation Efficiency |
93% (38/41) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014]
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality during organogenesis, neural tube defects, and developmental patterning abnormalities. Mice homozygous for a conditional allele activated in the early limb bud exhibit polydactyly and short limbs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700056E22Rik |
C |
T |
1: 184,033,505 (GRCm38) |
S119N |
probably benign |
Het |
| 4930503L19Rik |
T |
A |
18: 70,467,926 (GRCm38) |
|
probably null |
Het |
| 5430419D17Rik |
T |
C |
7: 131,238,182 (GRCm38) |
L611P |
probably damaging |
Het |
| Adam18 |
T |
C |
8: 24,647,853 (GRCm38) |
T324A |
probably benign |
Het |
| Adamts20 |
T |
A |
15: 94,286,371 (GRCm38) |
Q1517L |
probably benign |
Het |
| AI429214 |
A |
G |
8: 36,994,319 (GRCm38) |
Q207R |
probably benign |
Het |
| Arhgef7 |
A |
G |
8: 11,819,659 (GRCm38) |
T432A |
possibly damaging |
Het |
| Atad2b |
A |
G |
12: 5,031,784 (GRCm38) |
N1231S |
probably benign |
Het |
| Atp13a1 |
T |
C |
8: 69,802,144 (GRCm38) |
|
probably null |
Het |
| Atp6v0a1 |
T |
A |
11: 101,055,491 (GRCm38) |
L770* |
probably null |
Het |
| Atp8b3 |
T |
C |
10: 80,534,198 (GRCm38) |
N127S |
probably damaging |
Het |
| B3gnt5 |
T |
A |
16: 19,770,010 (GRCm38) |
D326E |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,565,861 (GRCm38) |
S372T |
probably damaging |
Het |
| Btbd9 |
T |
A |
17: 30,299,633 (GRCm38) |
D451V |
probably damaging |
Het |
| Cd46 |
T |
C |
1: 195,041,992 (GRCm38) |
*366W |
probably null |
Het |
| Cdh18 |
T |
A |
15: 23,473,995 (GRCm38) |
D650E |
probably damaging |
Het |
| Cenpc1 |
A |
T |
5: 86,037,908 (GRCm38) |
V248E |
probably damaging |
Het |
| Cep152 |
A |
G |
2: 125,594,899 (GRCm38) |
S574P |
probably benign |
Het |
| Chd2 |
A |
G |
7: 73,478,664 (GRCm38) |
S858P |
probably damaging |
Het |
| Cib4 |
T |
C |
5: 30,488,594 (GRCm38) |
D110G |
probably damaging |
Het |
| Col9a2 |
T |
A |
4: 121,039,788 (GRCm38) |
|
probably null |
Het |
| Csmd2 |
A |
T |
4: 128,496,188 (GRCm38) |
I2239F |
possibly damaging |
Het |
| Csmd3 |
C |
A |
15: 47,659,089 (GRCm38) |
G2728V |
probably damaging |
Het |
| Cxcl1 |
A |
T |
5: 90,891,767 (GRCm38) |
K85* |
probably null |
Het |
| Cyp2d11 |
A |
G |
15: 82,389,529 (GRCm38) |
L416P |
possibly damaging |
Het |
| Daam1 |
A |
C |
12: 71,915,784 (GRCm38) |
K90T |
unknown |
Het |
| Depdc5 |
T |
A |
5: 32,986,966 (GRCm38) |
M1435K |
possibly damaging |
Het |
| Diexf |
A |
T |
1: 193,114,703 (GRCm38) |
N573K |
probably damaging |
Het |
| Dip2c |
G |
A |
13: 9,576,908 (GRCm38) |
A632T |
probably damaging |
Het |
| Dld |
A |
T |
12: 31,334,054 (GRCm38) |
I350N |
probably damaging |
Het |
| Dmtf1 |
T |
A |
5: 9,127,987 (GRCm38) |
I391F |
possibly damaging |
Het |
| Dnah14 |
T |
C |
1: 181,752,145 (GRCm38) |
V3081A |
probably damaging |
Het |
| Efemp1 |
A |
G |
11: 28,854,538 (GRCm38) |
E22G |
probably damaging |
Het |
| Ephb6 |
A |
G |
6: 41,614,104 (GRCm38) |
D65G |
probably damaging |
Het |
| Fsip2 |
A |
T |
2: 82,977,092 (GRCm38) |
T1252S |
probably benign |
Het |
| Gm13084 |
T |
C |
4: 143,811,858 (GRCm38) |
Y181C |
probably damaging |
Het |
| Gm4847 |
A |
G |
1: 166,630,255 (GRCm38) |
S510P |
probably benign |
Het |
| Golga4 |
T |
C |
9: 118,537,273 (GRCm38) |
I365T |
probably damaging |
Het |
| Gp2 |
A |
T |
7: 119,454,543 (GRCm38) |
L65Q |
probably damaging |
Het |
| Ibtk |
T |
C |
9: 85,743,577 (GRCm38) |
Y40C |
probably damaging |
Het |
| Ice1 |
C |
A |
13: 70,602,427 (GRCm38) |
V1847L |
probably benign |
Het |
| Itgae |
C |
T |
11: 73,138,509 (GRCm38) |
Q1037* |
probably null |
Het |
| Kbtbd7 |
A |
G |
14: 79,427,430 (GRCm38) |
E234G |
possibly damaging |
Het |
| Khsrp |
T |
C |
17: 57,025,576 (GRCm38) |
T235A |
probably benign |
Het |
| Klk13 |
T |
C |
7: 43,721,158 (GRCm38) |
|
probably null |
Het |
| Lrfn5 |
G |
A |
12: 61,843,437 (GRCm38) |
G504D |
probably damaging |
Het |
| Macf1 |
A |
G |
4: 123,476,000 (GRCm38) |
V91A |
possibly damaging |
Het |
| Map6 |
G |
A |
7: 99,336,743 (GRCm38) |
G821D |
possibly damaging |
Het |
| Mark1 |
A |
C |
1: 184,921,604 (GRCm38) |
V167G |
probably damaging |
Het |
| Mrgprf |
T |
A |
7: 145,308,256 (GRCm38) |
L185Q |
probably damaging |
Het |
| Mtor |
T |
A |
4: 148,550,188 (GRCm38) |
V2422D |
probably damaging |
Het |
| Myh13 |
T |
A |
11: 67,332,520 (GRCm38) |
I222N |
probably damaging |
Het |
| Myh7b |
G |
A |
2: 155,620,427 (GRCm38) |
C350Y |
probably benign |
Het |
| Nfix |
G |
A |
8: 84,726,526 (GRCm38) |
R300C |
probably damaging |
Het |
| Olfm3 |
C |
A |
3: 115,101,986 (GRCm38) |
S172R |
probably benign |
Het |
| Olfr1168 |
A |
T |
2: 88,184,978 (GRCm38) |
T34S |
probably benign |
Het |
| Olfr1231 |
A |
T |
2: 89,303,184 (GRCm38) |
I136N |
probably damaging |
Het |
| Olfr342 |
A |
G |
2: 36,528,008 (GRCm38) |
I199V |
probably benign |
Het |
| Olfr70 |
A |
G |
4: 43,696,706 (GRCm38) |
S156P |
probably damaging |
Het |
| Olfr912 |
T |
A |
9: 38,581,283 (GRCm38) |
V2D |
possibly damaging |
Het |
| Pacs1 |
A |
T |
19: 5,143,829 (GRCm38) |
D557E |
probably damaging |
Het |
| Pde1c |
A |
G |
6: 56,361,815 (GRCm38) |
F11L |
probably benign |
Het |
| Phactr2 |
T |
C |
10: 13,247,139 (GRCm38) |
D343G |
possibly damaging |
Het |
| Piezo2 |
T |
C |
18: 63,015,802 (GRCm38) |
Y2659C |
probably damaging |
Het |
| Pkd2l2 |
A |
G |
18: 34,428,252 (GRCm38) |
T438A |
probably damaging |
Het |
| Pld2 |
T |
C |
11: 70,557,081 (GRCm38) |
W857R |
probably damaging |
Het |
| Plxnb1 |
T |
C |
9: 109,102,142 (GRCm38) |
V410A |
possibly damaging |
Het |
| Ptger2 |
A |
G |
14: 44,989,500 (GRCm38) |
Y179C |
probably damaging |
Het |
| Ptpro |
T |
A |
6: 137,443,594 (GRCm38) |
V1007D |
probably damaging |
Het |
| Rcan1 |
A |
T |
16: 92,393,520 (GRCm38) |
M177K |
probably benign |
Het |
| Rilpl1 |
A |
G |
5: 124,501,888 (GRCm38) |
I122T |
possibly damaging |
Het |
| Rilpl1 |
A |
G |
5: 124,501,871 (GRCm38) |
S156P |
probably benign |
Het |
| Rims4 |
C |
T |
2: 163,863,929 (GRCm38) |
V262M |
possibly damaging |
Het |
| Rpa1 |
C |
T |
11: 75,312,973 (GRCm38) |
|
probably null |
Het |
| Saxo2 |
A |
G |
7: 82,634,870 (GRCm38) |
V260A |
probably benign |
Het |
| Sel1l |
T |
C |
12: 91,824,860 (GRCm38) |
Y309C |
probably damaging |
Het |
| Setd1b |
GCCCCCCC |
GCCCCCCCCCCCCC |
5: 123,160,703 (GRCm38) |
|
probably benign |
Het |
| Slc33a1 |
A |
G |
3: 63,943,304 (GRCm38) |
F533S |
probably benign |
Het |
| Slc38a4 |
C |
T |
15: 97,005,858 (GRCm38) |
V421M |
probably benign |
Het |
| Snx14 |
A |
G |
9: 88,400,721 (GRCm38) |
|
probably null |
Het |
| Spef2 |
A |
G |
15: 9,716,396 (GRCm38) |
F368S |
probably damaging |
Het |
| Sri |
A |
T |
5: 8,059,381 (GRCm38) |
Q55L |
probably damaging |
Het |
| Stat4 |
A |
G |
1: 52,096,820 (GRCm38) |
I429M |
probably damaging |
Het |
| Stkld1 |
A |
T |
2: 26,951,450 (GRCm38) |
Q469L |
probably benign |
Het |
| Tm9sf1 |
T |
C |
14: 55,642,935 (GRCm38) |
T2A |
possibly damaging |
Het |
| Tmco5 |
A |
G |
2: 116,883,218 (GRCm38) |
T122A |
probably benign |
Het |
| Tmem59l |
G |
A |
8: 70,486,060 (GRCm38) |
P124S |
possibly damaging |
Het |
| Tmem81 |
G |
A |
1: 132,507,924 (GRCm38) |
R156Q |
probably damaging |
Het |
| Trpv6 |
T |
A |
6: 41,625,188 (GRCm38) |
T396S |
probably benign |
Het |
| Usp24 |
T |
A |
4: 106,371,079 (GRCm38) |
Y780* |
probably null |
Het |
| Vmn1r120 |
A |
G |
7: 21,053,016 (GRCm38) |
C257R |
probably damaging |
Het |
| Vmn2r53 |
A |
G |
7: 12,601,392 (GRCm38) |
F114L |
probably damaging |
Het |
| Vwf |
A |
G |
6: 125,643,006 (GRCm38) |
E1549G |
probably damaging |
Het |
| Zfp626 |
G |
A |
7: 27,818,482 (GRCm38) |
R296H |
probably damaging |
Het |
|
| Other mutations in Ift172 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Ift172
|
APN |
5 |
31,275,896 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01399:Ift172
|
APN |
5 |
31,266,248 (GRCm38) |
missense |
probably benign |
|
|
IGL01405:Ift172
|
APN |
5 |
31,261,852 (GRCm38) |
nonsense |
probably null |
|
|
IGL01562:Ift172
|
APN |
5 |
31,267,247 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL01758:Ift172
|
APN |
5 |
31,280,714 (GRCm38) |
missense |
probably benign |
|
|
IGL01792:Ift172
|
APN |
5 |
31,276,871 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01830:Ift172
|
APN |
5 |
31,285,292 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01839:Ift172
|
APN |
5 |
31,266,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02007:Ift172
|
APN |
5 |
31,286,604 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL02172:Ift172
|
APN |
5 |
31,281,337 (GRCm38) |
splice site |
probably benign |
|
|
IGL02190:Ift172
|
APN |
5 |
31,254,458 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
IGL02334:Ift172
|
APN |
5 |
31,283,058 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02486:Ift172
|
APN |
5 |
31,257,583 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02517:Ift172
|
APN |
5 |
31,253,648 (GRCm38) |
splice site |
probably null |
|
|
IGL02571:Ift172
|
APN |
5 |
31,257,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02626:Ift172
|
APN |
5 |
31,264,496 (GRCm38) |
missense |
probably benign |
|
|
IGL03183:Ift172
|
APN |
5 |
31,272,004 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL03277:Ift172
|
APN |
5 |
31,267,298 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL03349:Ift172
|
APN |
5 |
31,284,130 (GRCm38) |
missense |
probably benign |
0.05 |
|
ostinato
|
UTSW |
5 |
31,276,940 (GRCm38) |
missense |
probably benign |
0.10 |
|
pushback
|
UTSW |
5 |
31,286,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
P0042:Ift172
|
UTSW |
5 |
31,261,455 (GRCm38) |
missense |
probably benign |
0.35 |
|
PIT4802001:Ift172
|
UTSW |
5 |
31,285,266 (GRCm38) |
missense |
probably benign |
0.03 |
|
R0153:Ift172
|
UTSW |
5 |
31,260,624 (GRCm38) |
missense |
probably benign |
|
|
R0328:Ift172
|
UTSW |
5 |
31,263,851 (GRCm38) |
nonsense |
probably null |
|
|
R0357:Ift172
|
UTSW |
5 |
31,257,900 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R0369:Ift172
|
UTSW |
5 |
31,253,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0391:Ift172
|
UTSW |
5 |
31,286,667 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0512:Ift172
|
UTSW |
5 |
31,285,477 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0546:Ift172
|
UTSW |
5 |
31,257,601 (GRCm38) |
missense |
probably benign |
0.14 |
|
R0553:Ift172
|
UTSW |
5 |
31,275,842 (GRCm38) |
splice site |
probably benign |
|
|
R0606:Ift172
|
UTSW |
5 |
31,254,313 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0834:Ift172
|
UTSW |
5 |
31,257,371 (GRCm38) |
missense |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,257,918 (GRCm38) |
unclassified |
probably benign |
|
|
R1189:Ift172
|
UTSW |
5 |
31,285,830 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R1205:Ift172
|
UTSW |
5 |
31,285,792 (GRCm38) |
missense |
probably benign |
|
|
R1289:Ift172
|
UTSW |
5 |
31,280,976 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1342:Ift172
|
UTSW |
5 |
31,261,866 (GRCm38) |
missense |
probably benign |
|
|
R1395:Ift172
|
UTSW |
5 |
31,285,238 (GRCm38) |
unclassified |
probably benign |
|
|
R1417:Ift172
|
UTSW |
5 |
31,256,649 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2020:Ift172
|
UTSW |
5 |
31,267,241 (GRCm38) |
nonsense |
probably null |
|
|
R2111:Ift172
|
UTSW |
5 |
31,286,079 (GRCm38) |
missense |
probably benign |
0.04 |
|
R2175:Ift172
|
UTSW |
5 |
31,266,685 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2509:Ift172
|
UTSW |
5 |
31,262,968 (GRCm38) |
missense |
probably benign |
|
|
R2870:Ift172
|
UTSW |
5 |
31,257,861 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2870:Ift172
|
UTSW |
5 |
31,257,861 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,257,861 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,257,861 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,257,861 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,257,861 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3705:Ift172
|
UTSW |
5 |
31,261,437 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3793:Ift172
|
UTSW |
5 |
31,257,581 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R4385:Ift172
|
UTSW |
5 |
31,286,967 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4477:Ift172
|
UTSW |
5 |
31,265,437 (GRCm38) |
missense |
probably benign |
0.38 |
|
R4590:Ift172
|
UTSW |
5 |
31,253,955 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4663:Ift172
|
UTSW |
5 |
31,284,215 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4665:Ift172
|
UTSW |
5 |
31,285,254 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4977:Ift172
|
UTSW |
5 |
31,272,116 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R5109:Ift172
|
UTSW |
5 |
31,265,986 (GRCm38) |
missense |
probably benign |
0.06 |
|
R5182:Ift172
|
UTSW |
5 |
31,267,614 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R5343:Ift172
|
UTSW |
5 |
31,263,812 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5465:Ift172
|
UTSW |
5 |
31,261,518 (GRCm38) |
splice site |
probably null |
|
|
R5622:Ift172
|
UTSW |
5 |
31,283,082 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5718:Ift172
|
UTSW |
5 |
31,255,277 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5793:Ift172
|
UTSW |
5 |
31,276,948 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R5870:Ift172
|
UTSW |
5 |
31,276,940 (GRCm38) |
missense |
probably benign |
0.10 |
|
R5919:Ift172
|
UTSW |
5 |
31,260,662 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R5968:Ift172
|
UTSW |
5 |
31,261,484 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6112:Ift172
|
UTSW |
5 |
31,256,897 (GRCm38) |
missense |
probably benign |
|
|
R6339:Ift172
|
UTSW |
5 |
31,286,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6339:Ift172
|
UTSW |
5 |
31,256,583 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6355:Ift172
|
UTSW |
5 |
31,284,157 (GRCm38) |
missense |
probably benign |
0.33 |
|
R6565:Ift172
|
UTSW |
5 |
31,275,883 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R6668:Ift172
|
UTSW |
5 |
31,255,339 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6755:Ift172
|
UTSW |
5 |
31,260,998 (GRCm38) |
nonsense |
probably null |
|
|
R6818:Ift172
|
UTSW |
5 |
31,265,960 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6939:Ift172
|
UTSW |
5 |
31,257,586 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6980:Ift172
|
UTSW |
5 |
31,257,386 (GRCm38) |
missense |
probably benign |
|
|
R7047:Ift172
|
UTSW |
5 |
31,275,894 (GRCm38) |
nonsense |
probably null |
|
|
R7156:Ift172
|
UTSW |
5 |
31,272,075 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7180:Ift172
|
UTSW |
5 |
31,254,262 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7288:Ift172
|
UTSW |
5 |
31,285,286 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7351:Ift172
|
UTSW |
5 |
31,275,896 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7706:Ift172
|
UTSW |
5 |
31,266,379 (GRCm38) |
nonsense |
probably null |
|
|
R7890:Ift172
|
UTSW |
5 |
31,283,081 (GRCm38) |
nonsense |
probably null |
|
|
R7980:Ift172
|
UTSW |
5 |
31,260,644 (GRCm38) |
missense |
probably benign |
|
|
R8263:Ift172
|
UTSW |
5 |
31,265,337 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R8559:Ift172
|
UTSW |
5 |
31,256,577 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8717:Ift172
|
UTSW |
5 |
31,255,641 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8774:Ift172
|
UTSW |
5 |
31,257,863 (GRCm38) |
missense |
probably benign |
0.45 |
|
R8774-TAIL:Ift172
|
UTSW |
5 |
31,257,863 (GRCm38) |
missense |
probably benign |
0.45 |
|
R9037:Ift172
|
UTSW |
5 |
31,263,056 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R9038:Ift172
|
UTSW |
5 |
31,284,055 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R9133:Ift172
|
UTSW |
5 |
31,285,523 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9607:Ift172
|
UTSW |
5 |
31,253,569 (GRCm38) |
missense |
|
|
|
X0022:Ift172
|
UTSW |
5 |
31,285,320 (GRCm38) |
missense |
probably damaging |
0.97 |
|
Z1176:Ift172
|
UTSW |
5 |
31,276,924 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAGTGCACCTCCTCATTCAC -3'
(R):5'- CAGCCTGAAAGGAATCTCGGAG -3'
Sequencing Primer
(F):5'- CACTGTGATGTTGTCTGAGCTCC -3'
(R):5'- CCTGAAAGGAATCTCGGAGTGTGG -3'
|
| Posted On |
2014-10-02 |
Incidental Mutation