Incidental Mutation 'R0201:Dip2b'
| ID |
23676 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2b
|
| Ensembl Gene |
ENSMUSG00000023026 |
| Gene Name |
disco interacting protein 2 homolog B |
| Synonyms |
|
| MMRRC Submission |
038458-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.636)
|
| Stock # |
R0201 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
99936545-100117354 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 100084028 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Asparagine
at position 884
(D884N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097777
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023768]
[ENSMUST00000100203]
[ENSMUST00000108971]
|
| AlphaFold |
Q3UH60 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000023768
AA Change: D650N
PolyPhen 2
Score 0.195 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000023768
Gene: ENSMUSG00000023026
AA Change: D650N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AMP-binding
|
109 |
584 |
9.5e-26 |
PFAM |
|
Pfam:AMP-binding
|
760 |
1235 |
1.2e-52 |
PFAM |
|
low complexity region
|
1299 |
1311 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000100203
AA Change: D884N
PolyPhen 2
Score 0.978 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000097777
Gene: ENSMUSG00000023026
AA Change: D884N
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
12 |
130 |
1e-42 |
SMART |
|
low complexity region
|
152 |
168 |
N/A |
INTRINSIC |
|
low complexity region
|
181 |
192 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
341 |
817 |
2e-26 |
PFAM |
|
Pfam:AMP-binding
|
993 |
1468 |
1.8e-64 |
PFAM |
|
low complexity region
|
1532 |
1544 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108971
AA Change: D650N
PolyPhen 2
Score 0.195 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000104599
Gene: ENSMUSG00000023026
AA Change: D650N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AMP-binding
|
108 |
583 |
9.5e-26 |
PFAM |
|
Pfam:AMP-binding
|
759 |
1234 |
1.2e-52 |
PFAM |
|
low complexity region
|
1298 |
1310 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000229080
|
| Meta Mutation Damage Score |
0.3342 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 94.2%
|
| Validation Efficiency |
97% (91/94) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamdec1 |
A |
G |
14: 68,819,406 (GRCm39) |
|
probably null |
Het |
| Adamts16 |
T |
A |
13: 70,927,763 (GRCm39) |
Q492L |
possibly damaging |
Het |
| Aplnr |
A |
G |
2: 84,967,521 (GRCm39) |
D182G |
probably damaging |
Het |
| Arnt2 |
G |
T |
7: 84,010,867 (GRCm39) |
S3* |
probably null |
Het |
| Asxl3 |
T |
C |
18: 22,656,211 (GRCm39) |
V1407A |
probably benign |
Het |
| Atg13 |
A |
T |
2: 91,515,107 (GRCm39) |
|
probably null |
Het |
| Atm |
A |
T |
9: 53,365,579 (GRCm39) |
|
probably benign |
Het |
| Birc6 |
T |
G |
17: 74,916,322 (GRCm39) |
V1746G |
possibly damaging |
Het |
| Cbln1 |
G |
T |
8: 88,198,741 (GRCm39) |
T43K |
probably benign |
Het |
| Cbx5 |
T |
C |
15: 103,108,127 (GRCm39) |
T173A |
probably damaging |
Het |
| Cc2d2a |
A |
G |
5: 43,894,854 (GRCm39) |
Y1437C |
probably damaging |
Het |
| Ccdc78 |
C |
A |
17: 26,008,210 (GRCm39) |
|
probably benign |
Het |
| Cd2bp2 |
A |
G |
7: 126,793,000 (GRCm39) |
Y341H |
probably damaging |
Het |
| Cdhr5 |
T |
A |
7: 140,856,291 (GRCm39) |
D88V |
probably damaging |
Het |
| Ces1f |
T |
A |
8: 93,993,957 (GRCm39) |
T275S |
probably null |
Het |
| Cimip4 |
T |
A |
15: 78,263,028 (GRCm39) |
M209L |
probably damaging |
Het |
| Clca4a |
T |
C |
3: 144,666,478 (GRCm39) |
N458S |
probably benign |
Het |
| Cog5 |
A |
G |
12: 31,889,840 (GRCm39) |
K521R |
probably damaging |
Het |
| Csf2ra |
T |
A |
19: 61,214,006 (GRCm39) |
T305S |
probably benign |
Het |
| Csmd3 |
T |
A |
15: 47,483,125 (GRCm39) |
|
probably benign |
Het |
| Cts6 |
T |
A |
13: 61,349,313 (GRCm39) |
R132* |
probably null |
Het |
| D5Ertd579e |
G |
T |
5: 36,773,809 (GRCm39) |
N195K |
probably damaging |
Het |
| Ddx1 |
A |
G |
12: 13,273,809 (GRCm39) |
V606A |
probably damaging |
Het |
| Ehhadh |
A |
G |
16: 21,592,243 (GRCm39) |
|
probably null |
Het |
| Enpp1 |
T |
A |
10: 24,529,815 (GRCm39) |
T608S |
probably benign |
Het |
| Fancm |
T |
C |
12: 65,148,406 (GRCm39) |
Y674H |
probably damaging |
Het |
| Fat4 |
T |
A |
3: 38,945,745 (GRCm39) |
V1546D |
probably damaging |
Het |
| Fsd1 |
G |
A |
17: 56,297,522 (GRCm39) |
A158T |
probably benign |
Het |
| Fzd2 |
T |
A |
11: 102,496,948 (GRCm39) |
M464K |
probably damaging |
Het |
| Gjc2 |
A |
G |
11: 59,068,416 (GRCm39) |
F22S |
possibly damaging |
Het |
| Gria2 |
T |
C |
3: 80,615,145 (GRCm39) |
Y445C |
probably damaging |
Het |
| Hsdl1 |
T |
A |
8: 120,292,995 (GRCm39) |
I147F |
possibly damaging |
Het |
| Ifi44 |
T |
C |
3: 151,451,273 (GRCm39) |
Y226C |
probably damaging |
Het |
| Il16 |
A |
G |
7: 83,371,516 (GRCm39) |
C97R |
probably damaging |
Het |
| Impg1 |
A |
T |
9: 80,252,843 (GRCm39) |
S369T |
probably damaging |
Het |
| Jmjd1c |
A |
G |
10: 67,054,888 (GRCm39) |
T390A |
unknown |
Het |
| Lgi1 |
A |
G |
19: 38,289,741 (GRCm39) |
E269G |
possibly damaging |
Het |
| Lrp6 |
G |
T |
6: 134,427,860 (GRCm39) |
Y1577* |
probably null |
Het |
| Lrrc74a |
G |
T |
12: 86,808,547 (GRCm39) |
|
probably benign |
Het |
| Man1c1 |
A |
T |
4: 134,367,709 (GRCm39) |
|
probably null |
Het |
| Map1lc3b |
A |
C |
8: 122,317,289 (GRCm39) |
Q9P |
possibly damaging |
Het |
| Mboat1 |
G |
A |
13: 30,386,358 (GRCm39) |
R124H |
probably benign |
Het |
| Mcu |
A |
G |
10: 59,292,499 (GRCm39) |
L60P |
probably damaging |
Het |
| Mrs2 |
G |
T |
13: 25,202,517 (GRCm39) |
Q75K |
probably benign |
Het |
| Muc2 |
CGTG |
CGTGTG |
7: 141,699,185 (GRCm38) |
|
probably null |
Het |
| Neb |
G |
A |
2: 52,096,890 (GRCm39) |
|
probably benign |
Het |
| Nlrp2 |
C |
T |
7: 5,331,328 (GRCm39) |
G356D |
probably benign |
Het |
| Notch3 |
A |
G |
17: 32,375,122 (GRCm39) |
|
probably benign |
Het |
| Npr2 |
A |
C |
4: 43,641,617 (GRCm39) |
S474R |
probably damaging |
Het |
| Nup58 |
A |
G |
14: 60,482,065 (GRCm39) |
F100L |
probably benign |
Het |
| Osbpl6 |
A |
C |
2: 76,376,386 (GRCm39) |
D87A |
possibly damaging |
Het |
| Pabpc2 |
A |
T |
18: 39,908,360 (GRCm39) |
M542L |
probably benign |
Het |
| Papln |
A |
G |
12: 83,829,801 (GRCm39) |
|
probably benign |
Het |
| Parpbp |
T |
C |
10: 87,928,758 (GRCm39) |
I561V |
possibly damaging |
Het |
| Pcdhb13 |
C |
T |
18: 37,575,634 (GRCm39) |
A4V |
probably benign |
Het |
| Pelp1 |
T |
C |
11: 70,286,530 (GRCm39) |
T533A |
possibly damaging |
Het |
| Poldip3 |
T |
A |
15: 83,019,497 (GRCm39) |
M182L |
probably benign |
Het |
| Por |
T |
C |
5: 135,760,032 (GRCm39) |
S240P |
possibly damaging |
Het |
| Pramel15 |
A |
T |
4: 144,103,843 (GRCm39) |
|
probably benign |
Het |
| Pramel28 |
T |
C |
4: 143,691,460 (GRCm39) |
E421G |
probably damaging |
Het |
| Prss22 |
A |
T |
17: 24,215,275 (GRCm39) |
V167D |
probably damaging |
Het |
| Prss37 |
A |
C |
6: 40,493,283 (GRCm39) |
L61R |
probably damaging |
Het |
| Psmd1 |
C |
T |
1: 86,046,338 (GRCm39) |
T702M |
probably benign |
Het |
| Pxdn |
G |
T |
12: 30,052,430 (GRCm39) |
G869V |
possibly damaging |
Het |
| Rabgap1l |
A |
G |
1: 160,281,315 (GRCm39) |
|
probably benign |
Het |
| Rapgef6 |
T |
C |
11: 54,510,767 (GRCm39) |
V228A |
probably damaging |
Het |
| Rnf169 |
T |
C |
7: 99,575,210 (GRCm39) |
R462G |
possibly damaging |
Het |
| Rnft2 |
A |
G |
5: 118,332,745 (GRCm39) |
|
probably benign |
Het |
| Sgo2b |
T |
C |
8: 64,379,670 (GRCm39) |
D1054G |
probably benign |
Het |
| Sh3bgr |
T |
C |
16: 96,029,717 (GRCm39) |
|
probably benign |
Het |
| Slc12a4 |
A |
G |
8: 106,671,982 (GRCm39) |
V910A |
possibly damaging |
Het |
| Slc6a12 |
A |
T |
6: 121,332,331 (GRCm39) |
I222F |
probably benign |
Het |
| Spty2d1 |
G |
A |
7: 46,647,649 (GRCm39) |
R427* |
probably null |
Het |
| Ssc5d |
A |
G |
7: 4,947,662 (GRCm39) |
T1339A |
probably benign |
Het |
| Sspo |
A |
C |
6: 48,432,686 (GRCm39) |
E854A |
possibly damaging |
Het |
| Stx7 |
A |
G |
10: 24,060,977 (GRCm39) |
|
probably benign |
Het |
| Styk1 |
A |
T |
6: 131,278,693 (GRCm39) |
|
probably benign |
Het |
| Tmem163 |
T |
G |
1: 127,596,374 (GRCm39) |
|
probably benign |
Het |
| Tmppe |
C |
CT |
9: 114,233,707 (GRCm39) |
|
probably null |
Het |
| Tmx2 |
A |
G |
2: 84,503,426 (GRCm39) |
V229A |
probably benign |
Het |
| Top2b |
T |
C |
14: 16,383,174 (GRCm38) |
L54P |
probably damaging |
Het |
| Trim62 |
A |
T |
4: 128,796,343 (GRCm39) |
Y280F |
probably benign |
Het |
| Tssk4 |
A |
T |
14: 55,889,016 (GRCm39) |
K181* |
probably null |
Het |
| Tssk4 |
A |
T |
14: 55,889,017 (GRCm39) |
K181M |
probably damaging |
Het |
| Ubn1 |
A |
G |
16: 4,882,478 (GRCm39) |
D313G |
probably damaging |
Het |
| Ugt1a10 |
C |
T |
1: 88,142,845 (GRCm39) |
P113L |
probably damaging |
Het |
| Ugt1a10 |
C |
T |
1: 88,145,971 (GRCm39) |
P473L |
probably damaging |
Het |
|
| Other mutations in Dip2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00515:Dip2b
|
APN |
15 |
100,072,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01716:Dip2b
|
APN |
15 |
100,107,517 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01893:Dip2b
|
APN |
15 |
100,069,101 (GRCm39) |
splice site |
probably benign |
|
|
IGL01915:Dip2b
|
APN |
15 |
100,076,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02125:Dip2b
|
APN |
15 |
100,084,131 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
IGL02200:Dip2b
|
APN |
15 |
100,049,083 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02506:Dip2b
|
APN |
15 |
100,055,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02571:Dip2b
|
APN |
15 |
100,055,766 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02706:Dip2b
|
APN |
15 |
100,113,192 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02983:Dip2b
|
APN |
15 |
100,029,903 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03120:Dip2b
|
APN |
15 |
100,101,008 (GRCm39) |
splice site |
probably benign |
|
|
IGL03181:Dip2b
|
APN |
15 |
100,113,088 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03229:Dip2b
|
APN |
15 |
100,105,719 (GRCm39) |
splice site |
probably benign |
|
|
IGL03399:Dip2b
|
APN |
15 |
100,073,208 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
PIT4131001:Dip2b
|
UTSW |
15 |
100,100,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2b
|
UTSW |
15 |
100,067,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Dip2b
|
UTSW |
15 |
100,113,121 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0058:Dip2b
|
UTSW |
15 |
100,113,121 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0092:Dip2b
|
UTSW |
15 |
100,100,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0359:Dip2b
|
UTSW |
15 |
100,109,874 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0390:Dip2b
|
UTSW |
15 |
100,091,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0564:Dip2b
|
UTSW |
15 |
100,060,600 (GRCm39) |
nonsense |
probably null |
|
|
R0730:Dip2b
|
UTSW |
15 |
100,069,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1144:Dip2b
|
UTSW |
15 |
100,052,131 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1200:Dip2b
|
UTSW |
15 |
100,107,626 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1506:Dip2b
|
UTSW |
15 |
100,080,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1750:Dip2b
|
UTSW |
15 |
100,076,347 (GRCm39) |
missense |
probably benign |
|
|
R1760:Dip2b
|
UTSW |
15 |
100,109,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1773:Dip2b
|
UTSW |
15 |
100,091,842 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1812:Dip2b
|
UTSW |
15 |
100,096,819 (GRCm39) |
splice site |
probably null |
|
|
R2264:Dip2b
|
UTSW |
15 |
100,101,097 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3105:Dip2b
|
UTSW |
15 |
100,040,018 (GRCm39) |
nonsense |
probably null |
|
|
R4029:Dip2b
|
UTSW |
15 |
100,084,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4030:Dip2b
|
UTSW |
15 |
100,084,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4296:Dip2b
|
UTSW |
15 |
100,079,217 (GRCm39) |
missense |
probably benign |
|
|
R4392:Dip2b
|
UTSW |
15 |
100,059,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4480:Dip2b
|
UTSW |
15 |
100,084,182 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4564:Dip2b
|
UTSW |
15 |
100,055,139 (GRCm39) |
nonsense |
probably null |
|
|
R4605:Dip2b
|
UTSW |
15 |
100,107,517 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4606:Dip2b
|
UTSW |
15 |
100,113,210 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4634:Dip2b
|
UTSW |
15 |
100,058,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4667:Dip2b
|
UTSW |
15 |
100,049,241 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4739:Dip2b
|
UTSW |
15 |
100,105,658 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4826:Dip2b
|
UTSW |
15 |
100,067,162 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4870:Dip2b
|
UTSW |
15 |
100,093,665 (GRCm39) |
splice site |
probably null |
|
|
R4877:Dip2b
|
UTSW |
15 |
100,058,410 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4932:Dip2b
|
UTSW |
15 |
100,069,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5009:Dip2b
|
UTSW |
15 |
100,093,665 (GRCm39) |
splice site |
probably null |
|
|
R5169:Dip2b
|
UTSW |
15 |
100,102,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5216:Dip2b
|
UTSW |
15 |
100,109,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5218:Dip2b
|
UTSW |
15 |
100,052,177 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5274:Dip2b
|
UTSW |
15 |
100,109,985 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5370:Dip2b
|
UTSW |
15 |
100,109,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5420:Dip2b
|
UTSW |
15 |
100,103,054 (GRCm39) |
intron |
probably benign |
|
|
R5447:Dip2b
|
UTSW |
15 |
100,109,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5670:Dip2b
|
UTSW |
15 |
100,087,985 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5768:Dip2b
|
UTSW |
15 |
100,055,826 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5908:Dip2b
|
UTSW |
15 |
100,049,065 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5957:Dip2b
|
UTSW |
15 |
100,107,575 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5987:Dip2b
|
UTSW |
15 |
100,087,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6260:Dip2b
|
UTSW |
15 |
100,060,583 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6325:Dip2b
|
UTSW |
15 |
100,052,163 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6367:Dip2b
|
UTSW |
15 |
100,013,795 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6391:Dip2b
|
UTSW |
15 |
100,049,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Dip2b
|
UTSW |
15 |
100,096,892 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6818:Dip2b
|
UTSW |
15 |
100,091,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6922:Dip2b
|
UTSW |
15 |
100,091,724 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7002:Dip2b
|
UTSW |
15 |
100,058,346 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7076:Dip2b
|
UTSW |
15 |
100,055,853 (GRCm39) |
splice site |
probably null |
|
|
R7176:Dip2b
|
UTSW |
15 |
100,067,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7255:Dip2b
|
UTSW |
15 |
100,107,508 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7463:Dip2b
|
UTSW |
15 |
100,052,038 (GRCm39) |
missense |
probably benign |
|
|
R7513:Dip2b
|
UTSW |
15 |
100,105,629 (GRCm39) |
splice site |
probably null |
|
|
R7876:Dip2b
|
UTSW |
15 |
100,088,922 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8368:Dip2b
|
UTSW |
15 |
100,052,124 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9289:Dip2b
|
UTSW |
15 |
100,071,152 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9405:Dip2b
|
UTSW |
15 |
100,093,757 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9477:Dip2b
|
UTSW |
15 |
99,936,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9485:Dip2b
|
UTSW |
15 |
100,052,924 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9533:Dip2b
|
UTSW |
15 |
100,073,178 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9581:Dip2b
|
UTSW |
15 |
100,079,255 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9666:Dip2b
|
UTSW |
15 |
100,107,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0064:Dip2b
|
UTSW |
15 |
100,013,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTCTGCTTCACTGCACATTTACACG -3'
(R):5'- GTGGGCACATGAGGATATTACACGG -3'
Sequencing Primer
(F):5'- ACACGTCAGACAGTTCCTTGG -3'
(R):5'- TACACGGGTGTAGAGAACCCTC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation