Incidental Mutation 'IGL00225:Klrb1f'
ID2369
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Klrb1f
Ensembl Gene ENSMUSG00000030154
Gene Namekiller cell lectin-like receptor subfamily B member 1F
SynonymsNkrp1f, A630024B12Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL00225
Quality Score
Status
Chromosome6
Chromosomal Location129045901-129057464 bp(+) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) T to A at 129053175 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000145033 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000032257] [ENSMUST00000203059] [ENSMUST00000204320] [ENSMUST00000204508]
Predicted Effect probably benign
Transcript: ENSMUST00000032257
SMART Domains Protein: ENSMUSP00000032257
Gene: ENSMUSG00000030154

DomainStartEndE-ValueType
transmembrane domain 44 66 N/A INTRINSIC
CLECT 94 211 2.86e-20 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000203059
SMART Domains Protein: ENSMUSP00000145316
Gene: ENSMUSG00000030154

DomainStartEndE-ValueType
transmembrane domain 44 66 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000204320
SMART Domains Protein: ENSMUSP00000144813
Gene: ENSMUSG00000030154

DomainStartEndE-ValueType
low complexity region 41 64 N/A INTRINSIC
PDB:3M9Z|A 65 111 2e-7 PDB
Blast:CLECT 69 111 6e-25 BLAST
SCOP:d1e87a_ 69 111 2e-6 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000204413
Predicted Effect probably benign
Transcript: ENSMUST00000204508
SMART Domains Protein: ENSMUSP00000145033
Gene: ENSMUSG00000030154

DomainStartEndE-ValueType
transmembrane domain 39 61 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000204784
Predicted Effect noncoding transcript
Transcript: ENSMUST00000205038
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Flii T C 11: 60,723,415 N93D probably benign Het
Gm8356 T C 14: 6,537,141 K24E probably damaging Het
Hars G A 18: 36,768,172 T409M probably damaging Het
Ivns1abp A G 1: 151,351,112 probably null Het
Kcnq4 G A 4: 120,698,016 Q657* probably null Het
Kdm4c T G 4: 74,345,567 V696G probably benign Het
Lrp4 G A 2: 91,495,026 V1399I probably benign Het
Mki67 A G 7: 135,690,120 V3168A probably benign Het
Nf1 T A 11: 79,395,905 I177K probably damaging Het
Nnt A T 13: 119,369,997 N371K probably damaging Het
Olfr472 C T 7: 107,903,104 P129L probably damaging Het
Olfr60 A G 7: 140,345,210 Y260H probably damaging Het
Oraov1 G A 7: 144,917,668 G86D possibly damaging Het
Prkdc G T 16: 15,809,644 V3389L possibly damaging Het
Prr16 T A 18: 51,303,120 Y224N possibly damaging Het
Ptgs1 G A 2: 36,237,219 C39Y probably damaging Het
Sla T C 15: 66,782,630 D269G possibly damaging Het
Stk38l T A 6: 146,758,473 M1K probably null Het
Trim24 T A 6: 37,903,648 N160K possibly damaging Het
Zfp451 A G 1: 33,786,540 probably benign Het
Other mutations in Klrb1f
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00838:Klrb1f APN 6 129054316 missense possibly damaging 0.81
IGL03077:Klrb1f APN 6 129053802 missense probably null 0.99
R0352:Klrb1f UTSW 6 129053717 missense probably damaging 0.99
R0412:Klrb1f UTSW 6 129054331 missense probably benign 0.30
R1733:Klrb1f UTSW 6 129054359 nonsense probably null
R3237:Klrb1f UTSW 6 129054343 missense possibly damaging 0.58
R4849:Klrb1f UTSW 6 129056384 missense probably damaging 1.00
R4894:Klrb1f UTSW 6 129053188 missense probably benign 0.23
R5378:Klrb1f UTSW 6 129053831 missense probably damaging 1.00
R5610:Klrb1f UTSW 6 129054372 critical splice donor site probably null
R6916:Klrb1f UTSW 6 129053811 missense probably benign
R7412:Klrb1f UTSW 6 129056345 nonsense probably null
Z1177:Klrb1f UTSW 6 129052503 missense possibly damaging 0.77
Posted On2011-12-09