Mutagenetix > Incidental Mutation

Incidental Mutation 'R0180:Dnah9'

23837

Institutional Source

Beutler Lab

Gene Symbol

Dnah9

Ensembl Gene

ENSMUSG00000056752

Gene Name

dynein, axonemal, heavy chain 9

Synonyms

D11Ertd686e, Dnahc9

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.294) question?

Stock #

R0180 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

65831282-66168551 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 66147290 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Proline at position 140 (H140P)

Ref Sequence

ENSEMBL: ENSMUSP00000104331 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000080665] [ENSMUST00000108691]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000080665
AA Change: H338P

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000079494
Gene: ENSMUSG00000056752
AA Change: H338P

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	209	787	3.6e-164	PFAM
coiled coil region	788	820	N/A	INTRINSIC
low complexity region	1228	1240	N/A	INTRINSIC
Pfam:DHC_N2	1290	1699	1.4e-134	PFAM
AAA	1863	1999	4.9e-1	SMART
AAA	2141	2341	1.99e0	SMART
AAA	2468	2614	6.75e-1	SMART
Pfam:AAA_8	2786	3053	1.1e-165	PFAM
Pfam:MT	3065	3408	7.2e-208	PFAM
Pfam:AAA_9	3430	3652	3.2e-87	PFAM
Pfam:Dynein_heavy	3786	4482	1e-241	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000108691
AA Change: H140P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000104331
Gene: ENSMUSG00000056752
AA Change: H140P

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	10	457	2.3e-141	PFAM

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.8%
20x: 89.5%

Validation Efficiency

77% (53/69)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 74 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110059E24Rik	T	A	19: 21,652,639	N24Y	probably damaging	Het
2810408A11Rik	A	T	11: 69,898,876	M311K	probably benign	Het
Ackr2	T	C	9: 121,908,916	I119T	probably benign	Het
Adamtsl3	A	G	7: 82,575,990	M336V	probably benign	Het
Adhfe1	T	A	1: 9,563,857	F374I	probably benign	Het
Apob	C	T	12: 8,008,285	Q2256*	probably null	Het
Arg1	T	C	10: 24,916,830	I169V	probably benign	Het
Atxn1	A	G	13: 45,557,548	V636A	probably damaging	Het
B3gnt5	T	A	16: 19,769,100	I23K	possibly damaging	Het
Casc1	A	G	6: 145,183,218		probably benign	Het
Catsperg1	A	T	7: 29,190,431		probably null	Het
Celf3	T	A	3: 94,485,340	F115L	probably damaging	Het
Cep192	T	A	18: 67,835,488	H984Q	probably damaging	Het
Col18a1	A	G	10: 77,096,517	V493A	probably benign	Het
Col5a2	C	T	1: 45,411,460	G376S	probably damaging	Het
Colec12	C	T	18: 9,858,921	P568L	unknown	Het
Colec12	A	G	18: 9,848,890	H356R	probably damaging	Het
Cracr2a	T	C	6: 127,604,074		probably null	Het
Ctsr	T	C	13: 61,162,745	H62R	probably damaging	Het
Cyp4f40	G	T	17: 32,659,667	W61L	probably benign	Het
Dnm1	T	G	2: 32,327,993	I464L	probably damaging	Het
Dnmt1	G	A	9: 20,908,620	T1409I	probably damaging	Het
Dock1	G	A	7: 135,098,837	D1109N	probably damaging	Het
Efhc1	A	G	1: 20,967,489	M297V	probably benign	Het
Emcn	A	T	3: 137,418,994		probably null	Het
Ephb1	A	T	9: 101,927,504	M905K	probably damaging	Het
Fbxw10	A	G	11: 62,853,096	Y276C	probably benign	Het
Fermt3	C	A	19: 7,002,343	S474I	possibly damaging	Het
Frg1	T	A	8: 41,399,068		probably null	Het
Gbf1	T	C	19: 46,285,722	S1732P	probably benign	Het
Gbp8	A	C	5: 105,031,276	L119R	probably damaging	Het
Gldc	C	T	19: 30,100,817	A927T	possibly damaging	Het
Gm8836	T	A	6: 70,260,405		probably benign	Het
Grhl3	C	T	4: 135,554,530	V344I	probably benign	Het
Hhipl1	T	A	12: 108,328,070	L745H	probably damaging	Het
Ido1	T	C	8: 24,593,140	I90V	possibly damaging	Het
Itpr2	T	A	6: 146,501,909		probably benign	Het
Kif1b	T	G	4: 149,213,659	S1029R	probably damaging	Het
Kmt2a	G	A	9: 44,826,851		probably benign	Het
Limk1	T	C	5: 134,669,261	N215D	probably damaging	Het
Lims2	A	G	18: 31,956,315	K144E	probably benign	Het
Mfsd6l	A	T	11: 68,556,545	Q74L	possibly damaging	Het
Mroh1	T	A	15: 76,428,250	S546T	probably damaging	Het
Ncbp3	T	A	11: 73,064,978		probably null	Het
Nlrx1	G	A	9: 44,255,459	H776Y	possibly damaging	Het
Nptxr	T	C	15: 79,794,403	M228V	probably benign	Het
Nsf	T	A	11: 103,930,780	L13F	probably damaging	Het
Nyap1	T	C	5: 137,738,021	E68G	probably damaging	Het
Olfr550	A	G	7: 102,579,032	Y179C	probably damaging	Het
Olfr9	A	T	10: 128,990,834	R307S	possibly damaging	Het
Pcdhb9	A	G	18: 37,402,254	N434D	probably damaging	Het
Pgm5	T	C	19: 24,815,763	D313G	probably damaging	Het
Pkdcc	G	A	17: 83,221,870		probably null	Het
Pkp1	T	C	1: 135,886,800	K261R	probably benign	Het
Pnpla6	A	G	8: 3,524,250		probably null	Het
Polr3b	A	G	10: 84,622,515	T17A	probably benign	Het
Ppt2	A	T	17: 34,626,503	M98K	probably damaging	Het
Rasal3	T	C	17: 32,399,405	D142G	probably benign	Het
Rbm17	G	A	2: 11,587,779	S295L	probably benign	Het
Rhbdf1	A	T	11: 32,210,042	V153D	possibly damaging	Het
Slc6a3	C	T	13: 73,562,336	T355M	probably damaging	Het
Snrnp35	A	T	5: 124,490,820		probably benign	Het
Sorcs2	A	T	5: 36,153,845	I37N	probably damaging	Het
Tecta	G	T	9: 42,366,813	P1133Q	probably benign	Het
Tmem145	A	G	7: 25,314,699	I413V	probably benign	Het
Trappc11	G	T	8: 47,527,974	T144K	possibly damaging	Het
Triml2	A	T	8: 43,190,309	I223L	probably benign	Het
Ube2g2	T	A	10: 77,630,739	N19K	possibly damaging	Het
Ubqln3	A	G	7: 104,141,840	Y348H	probably damaging	Het
Wfs1	A	G	5: 36,967,028	F840L	probably damaging	Het
Zc3h11a	T	C	1: 133,621,611	I771V	probably benign	Het
Zdhhc23	G	A	16: 43,973,703	P203S	probably benign	Het
Zfp106	T	G	2: 120,533,875	T684P	probably damaging	Het
Zfp217	A	T	2: 170,120,137	L90Q	probably damaging	Het

Other mutations in Dnah9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00696:Dnah9	APN	11	65,841,238 (GRCm38)	splice site	probably benign
IGL00805:Dnah9	APN	11	65,881,695 (GRCm38)	missense	probably benign	0.00
IGL00826:Dnah9	APN	11	65,989,942 (GRCm38)	missense	probably damaging	1.00
IGL01108:Dnah9	APN	11	65,849,980 (GRCm38)	missense	possibly damaging	0.93
IGL01152:Dnah9	APN	11	66,072,056 (GRCm38)	missense	probably damaging	1.00
IGL01353:Dnah9	APN	11	66,080,571 (GRCm38)	missense	probably damaging	1.00
IGL01364:Dnah9	APN	11	66,155,459 (GRCm38)	missense	probably damaging	1.00
IGL01479:Dnah9	APN	11	65,955,717 (GRCm38)	missense	probably benign	0.14
IGL01537:Dnah9	APN	11	65,947,680 (GRCm38)	missense	probably benign
IGL01565:Dnah9	APN	11	66,033,829 (GRCm38)	missense	possibly damaging	0.95
IGL01597:Dnah9	APN	11	66,118,830 (GRCm38)	missense	probably damaging	1.00
IGL01619:Dnah9	APN	11	65,831,615 (GRCm38)	nonsense	probably null
IGL01625:Dnah9	APN	11	66,044,645 (GRCm38)	missense	probably damaging	1.00
IGL01803:Dnah9	APN	11	66,118,829 (GRCm38)	missense	probably damaging	1.00
IGL01819:Dnah9	APN	11	66,108,126 (GRCm38)	missense	probably benign	0.33
IGL01896:Dnah9	APN	11	66,130,666 (GRCm38)	missense	possibly damaging	0.89
IGL01922:Dnah9	APN	11	66,075,034 (GRCm38)	splice site	probably benign
IGL01923:Dnah9	APN	11	66,125,235 (GRCm38)	splice site	probably benign
IGL02059:Dnah9	APN	11	66,072,958 (GRCm38)	missense	probably damaging	1.00
IGL02068:Dnah9	APN	11	66,061,045 (GRCm38)	missense	probably damaging	1.00
IGL02135:Dnah9	APN	11	66,117,492 (GRCm38)	missense	possibly damaging	0.63
IGL02146:Dnah9	APN	11	65,927,700 (GRCm38)	missense	probably damaging	1.00
IGL02264:Dnah9	APN	11	66,080,488 (GRCm38)	splice site	probably benign
IGL02325:Dnah9	APN	11	65,834,217 (GRCm38)	missense	probably damaging	1.00
IGL02426:Dnah9	APN	11	66,125,153 (GRCm38)	missense	probably benign
IGL02440:Dnah9	APN	11	65,955,246 (GRCm38)	missense	probably damaging	1.00
IGL02471:Dnah9	APN	11	65,947,618 (GRCm38)	nonsense	probably null
IGL02496:Dnah9	APN	11	66,029,363 (GRCm38)	missense	probably damaging	1.00
IGL02672:Dnah9	APN	11	65,927,601 (GRCm38)	missense	probably benign	0.02
IGL02718:Dnah9	APN	11	65,886,640 (GRCm38)	missense	probably damaging	0.99
IGL02832:Dnah9	APN	11	66,040,346 (GRCm38)	missense	probably damaging	1.00
IGL02851:Dnah9	APN	11	66,037,744 (GRCm38)	splice site	probably benign
IGL02859:Dnah9	APN	11	65,881,619 (GRCm38)	splice site	probably benign
IGL02864:Dnah9	APN	11	66,061,003 (GRCm38)	missense	probably damaging	1.00
IGL02954:Dnah9	APN	11	66,118,967 (GRCm38)	missense	probably damaging	1.00
IGL02987:Dnah9	APN	11	65,841,273 (GRCm38)	missense	probably benign	0.23
IGL02987:Dnah9	APN	11	65,855,272 (GRCm38)	missense	probably damaging	0.98
IGL03160:Dnah9	APN	11	66,108,054 (GRCm38)	missense	probably damaging	0.98
IGL03171:Dnah9	APN	11	65,981,241 (GRCm38)	missense	probably benign	0.13
IGL03180:Dnah9	APN	11	65,886,639 (GRCm38)	missense	probably damaging	0.99
IGL03388:Dnah9	APN	11	65,947,542 (GRCm38)	missense	probably damaging	1.00
anarchy	UTSW	11	65,955,248 (GRCm38)	missense	probably damaging	0.99
sacco	UTSW	11	66,168,079 (GRCm38)	missense	possibly damaging	0.82
Tweed	UTSW	11	66,072,072 (GRCm38)	missense	probably damaging	0.99
vanzetti	UTSW	11	65,855,372 (GRCm38)	nonsense	probably null
IGL02837:Dnah9	UTSW	11	65,874,196 (GRCm38)	missense	probably damaging	1.00
PIT4280001:Dnah9	UTSW	11	66,005,013 (GRCm38)	missense	probably benign	0.44
R0021:Dnah9	UTSW	11	65,969,979 (GRCm38)	missense	probably benign	0.36
R0021:Dnah9	UTSW	11	65,969,979 (GRCm38)	missense	probably benign	0.36
R0025:Dnah9	UTSW	11	65,969,955 (GRCm38)	splice site	probably benign
R0025:Dnah9	UTSW	11	65,969,955 (GRCm38)	splice site	probably benign
R0070:Dnah9	UTSW	11	66,160,040 (GRCm38)	missense	probably benign	0.10
R0164:Dnah9	UTSW	11	65,918,804 (GRCm38)	nonsense	probably null
R0164:Dnah9	UTSW	11	65,918,804 (GRCm38)	nonsense	probably null
R0195:Dnah9	UTSW	11	65,895,905 (GRCm38)	missense	probably benign	0.30
R0230:Dnah9	UTSW	11	65,855,315 (GRCm38)	missense	probably damaging	1.00
R0243:Dnah9	UTSW	11	65,911,852 (GRCm38)	missense	possibly damaging	0.91
R0279:Dnah9	UTSW	11	65,911,789 (GRCm38)	critical splice donor site	probably null
R0288:Dnah9	UTSW	11	66,025,134 (GRCm38)	critical splice donor site	probably null
R0309:Dnah9	UTSW	11	66,026,972 (GRCm38)	splice site	probably benign
R0356:Dnah9	UTSW	11	66,130,562 (GRCm38)	critical splice donor site	probably null
R0403:Dnah9	UTSW	11	66,084,789 (GRCm38)	missense	possibly damaging	0.90
R0413:Dnah9	UTSW	11	66,108,135 (GRCm38)	missense	probably damaging	1.00
R0448:Dnah9	UTSW	11	65,918,713 (GRCm38)	splice site	probably benign
R0496:Dnah9	UTSW	11	66,075,135 (GRCm38)	missense	probably null	1.00
R0557:Dnah9	UTSW	11	66,084,666 (GRCm38)	missense	probably damaging	1.00
R0584:Dnah9	UTSW	11	65,990,489 (GRCm38)	missense	probably damaging	1.00
R0598:Dnah9	UTSW	11	66,118,877 (GRCm38)	missense	probably benign	0.02
R0599:Dnah9	UTSW	11	65,965,689 (GRCm38)	missense	probably damaging	1.00
R0606:Dnah9	UTSW	11	65,841,333 (GRCm38)	missense	probably damaging	1.00
R0666:Dnah9	UTSW	11	66,085,458 (GRCm38)	missense	probably benign	0.01
R0715:Dnah9	UTSW	11	66,081,248 (GRCm38)	splice site	probably benign
R0726:Dnah9	UTSW	11	65,965,681 (GRCm38)	missense	probably damaging	1.00
R0737:Dnah9	UTSW	11	66,107,898 (GRCm38)	missense	probably damaging	1.00
R0763:Dnah9	UTSW	11	66,155,530 (GRCm38)	missense	probably benign	0.30
R0792:Dnah9	UTSW	11	65,896,001 (GRCm38)	missense	possibly damaging	0.84
R0829:Dnah9	UTSW	11	66,005,176 (GRCm38)	missense	probably benign	0.00
R0973:Dnah9	UTSW	11	66,005,837 (GRCm38)	splice site	probably null
R0974:Dnah9	UTSW	11	66,005,837 (GRCm38)	splice site	probably null
R1055:Dnah9	UTSW	11	66,160,011 (GRCm38)	missense	probably damaging	1.00
R1081:Dnah9	UTSW	11	66,084,877 (GRCm38)	missense	probably damaging	0.99
R1184:Dnah9	UTSW	11	66,084,612 (GRCm38)	critical splice donor site	probably null
R1225:Dnah9	UTSW	11	65,871,060 (GRCm38)	missense	possibly damaging	0.94
R1304:Dnah9	UTSW	11	65,927,588 (GRCm38)	missense	probably damaging	0.98
R1417:Dnah9	UTSW	11	65,955,747 (GRCm38)	missense	probably damaging	0.96
R1439:Dnah9	UTSW	11	65,874,132 (GRCm38)	missense	probably benign	0.22
R1447:Dnah9	UTSW	11	66,108,482 (GRCm38)	missense	possibly damaging	0.65
R1450:Dnah9	UTSW	11	65,927,786 (GRCm38)	missense	probably damaging	1.00
R1470:Dnah9	UTSW	11	65,927,822 (GRCm38)	missense	probably benign	0.11
R1470:Dnah9	UTSW	11	65,927,822 (GRCm38)	missense	probably benign	0.11
R1486:Dnah9	UTSW	11	65,834,272 (GRCm38)	missense	probably damaging	1.00
R1519:Dnah9	UTSW	11	65,881,761 (GRCm38)	missense	probably damaging	0.96
R1570:Dnah9	UTSW	11	66,112,330 (GRCm38)	missense	probably benign
R1617:Dnah9	UTSW	11	65,895,921 (GRCm38)	missense	probably damaging	1.00
R1623:Dnah9	UTSW	11	66,037,637 (GRCm38)	missense	probably damaging	1.00
R1626:Dnah9	UTSW	11	66,085,267 (GRCm38)	missense	probably benign	0.05
R1671:Dnah9	UTSW	11	65,927,963 (GRCm38)	missense	probably damaging	0.99
R1694:Dnah9	UTSW	11	65,954,824 (GRCm38)	nonsense	probably null
R1701:Dnah9	UTSW	11	65,911,924 (GRCm38)	missense	probably damaging	1.00
R1702:Dnah9	UTSW	11	66,085,195 (GRCm38)	missense	possibly damaging	0.72
R1708:Dnah9	UTSW	11	65,915,154 (GRCm38)	missense	probably benign	0.11
R1718:Dnah9	UTSW	11	66,168,079 (GRCm38)	missense	possibly damaging	0.82
R1729:Dnah9	UTSW	11	66,085,020 (GRCm38)	missense	possibly damaging	0.51
R1760:Dnah9	UTSW	11	65,981,222 (GRCm38)	missense	probably benign	0.31
R1784:Dnah9	UTSW	11	66,085,020 (GRCm38)	missense	possibly damaging	0.51
R1793:Dnah9	UTSW	11	66,119,594 (GRCm38)	critical splice donor site	probably null
R1801:Dnah9	UTSW	11	65,955,297 (GRCm38)	missense	probably damaging	0.99
R1827:Dnah9	UTSW	11	65,850,061 (GRCm38)	missense	probably damaging	0.97
R1836:Dnah9	UTSW	11	66,118,841 (GRCm38)	missense	probably benign	0.10
R1840:Dnah9	UTSW	11	65,834,198 (GRCm38)	nonsense	probably null
R1847:Dnah9	UTSW	11	65,834,386 (GRCm38)	missense	probably damaging	1.00
R1872:Dnah9	UTSW	11	66,037,490 (GRCm38)	missense	probably benign	0.16
R1929:Dnah9	UTSW	11	65,976,398 (GRCm38)	missense	probably benign	0.05
R1969:Dnah9	UTSW	11	65,848,371 (GRCm38)	missense	probably damaging	1.00
R1971:Dnah9	UTSW	11	65,848,371 (GRCm38)	missense	probably damaging	1.00
R2027:Dnah9	UTSW	11	65,955,338 (GRCm38)	missense	probably benign	0.11
R2049:Dnah9	UTSW	11	66,044,683 (GRCm38)	missense	probably damaging	1.00
R2064:Dnah9	UTSW	11	66,145,435 (GRCm38)	missense	probably benign	0.31
R2104:Dnah9	UTSW	11	66,061,124 (GRCm38)	missense	probably damaging	1.00
R2109:Dnah9	UTSW	11	66,037,585 (GRCm38)	missense	probably damaging	1.00
R2160:Dnah9	UTSW	11	66,117,483 (GRCm38)	missense	probably damaging	1.00
R2172:Dnah9	UTSW	11	66,072,779 (GRCm38)	missense	probably damaging	1.00
R2198:Dnah9	UTSW	11	65,859,499 (GRCm38)	missense	possibly damaging	0.50
R2271:Dnah9	UTSW	11	66,112,362 (GRCm38)	missense	probably benign	0.37
R2272:Dnah9	UTSW	11	66,112,362 (GRCm38)	missense	probably benign	0.37
R2396:Dnah9	UTSW	11	66,085,158 (GRCm38)	missense	probably benign	0.01
R2398:Dnah9	UTSW	11	65,915,203 (GRCm38)	missense	probably damaging	1.00
R2418:Dnah9	UTSW	11	66,095,415 (GRCm38)	nonsense	probably null
R2419:Dnah9	UTSW	11	66,095,415 (GRCm38)	nonsense	probably null
R2510:Dnah9	UTSW	11	66,005,169 (GRCm38)	missense	probably damaging	1.00
R2680:Dnah9	UTSW	11	66,033,925 (GRCm38)	missense	probably benign	0.00
R2875:Dnah9	UTSW	11	66,168,461 (GRCm38)	missense	possibly damaging	0.89
R2979:Dnah9	UTSW	11	66,117,588 (GRCm38)	missense	possibly damaging	0.89
R3236:Dnah9	UTSW	11	65,954,989 (GRCm38)	missense	probably benign	0.11
R3237:Dnah9	UTSW	11	65,954,989 (GRCm38)	missense	probably benign	0.11
R3433:Dnah9	UTSW	11	66,075,112 (GRCm38)	missense	possibly damaging	0.85
R3737:Dnah9	UTSW	11	66,156,908 (GRCm38)	nonsense	probably null
R3820:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3821:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3822:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3861:Dnah9	UTSW	11	66,052,994 (GRCm38)	splice site	probably benign
R3918:Dnah9	UTSW	11	65,870,974 (GRCm38)	missense	possibly damaging	0.54
R4011:Dnah9	UTSW	11	65,834,464 (GRCm38)	missense	probably damaging	0.98
R4044:Dnah9	UTSW	11	66,133,635 (GRCm38)	missense	probably benign	0.03
R4072:Dnah9	UTSW	11	66,084,904 (GRCm38)	missense	probably benign	0.00
R4076:Dnah9	UTSW	11	66,084,904 (GRCm38)	missense	probably benign	0.00
R4097:Dnah9	UTSW	11	65,990,459 (GRCm38)	missense	probably damaging	1.00
R4409:Dnah9	UTSW	11	66,085,477 (GRCm38)	missense	possibly damaging	0.51
R4410:Dnah9	UTSW	11	66,085,477 (GRCm38)	missense	possibly damaging	0.51
R4417:Dnah9	UTSW	11	65,981,214 (GRCm38)	missense	possibly damaging	0.75
R4420:Dnah9	UTSW	11	66,118,749 (GRCm38)	missense	probably benign	0.00
R4434:Dnah9	UTSW	11	66,108,075 (GRCm38)	missense	possibly damaging	0.67
R4451:Dnah9	UTSW	11	65,881,641 (GRCm38)	missense	probably benign	0.07
R4452:Dnah9	UTSW	11	66,027,082 (GRCm38)	missense	probably damaging	0.96
R4454:Dnah9	UTSW	11	66,147,389 (GRCm38)	missense	probably damaging	0.96
R4551:Dnah9	UTSW	11	65,841,366 (GRCm38)	missense	probably damaging	1.00
R4552:Dnah9	UTSW	11	65,841,366 (GRCm38)	missense	probably damaging	1.00
R4590:Dnah9	UTSW	11	66,040,392 (GRCm38)	missense	probably damaging	1.00
R4595:Dnah9	UTSW	11	66,168,152 (GRCm38)	missense	probably benign
R4655:Dnah9	UTSW	11	65,955,732 (GRCm38)	missense	probably benign	0.00
R4667:Dnah9	UTSW	11	66,155,531 (GRCm38)	missense	probably benign
R4718:Dnah9	UTSW	11	66,085,473 (GRCm38)	missense	probably benign
R4720:Dnah9	UTSW	11	66,076,358 (GRCm38)	missense	probably damaging	1.00
R4734:Dnah9	UTSW	11	65,834,115 (GRCm38)	missense	probably damaging	1.00
R4749:Dnah9	UTSW	11	65,834,115 (GRCm38)	missense	probably damaging	1.00
R4765:Dnah9	UTSW	11	65,927,726 (GRCm38)	missense	probably damaging	1.00
R4905:Dnah9	UTSW	11	65,874,124 (GRCm38)	nonsense	probably null
R4963:Dnah9	UTSW	11	66,084,611 (GRCm38)	splice site	probably null
R5074:Dnah9	UTSW	11	65,850,040 (GRCm38)	missense	probably damaging	1.00
R5230:Dnah9	UTSW	11	66,084,666 (GRCm38)	missense	probably damaging	0.99
R5262:Dnah9	UTSW	11	66,112,333 (GRCm38)	missense	probably benign	0.34
R5364:Dnah9	UTSW	11	65,881,696 (GRCm38)	missense	possibly damaging	0.93
R5370:Dnah9	UTSW	11	66,029,354 (GRCm38)	missense	probably damaging	1.00
R5386:Dnah9	UTSW	11	66,029,356 (GRCm38)	missense	probably damaging	1.00
R5389:Dnah9	UTSW	11	66,095,314 (GRCm38)	nonsense	probably null
R5541:Dnah9	UTSW	11	66,145,336 (GRCm38)	missense	probably damaging	1.00
R5560:Dnah9	UTSW	11	65,881,740 (GRCm38)	missense	probably benign	0.00
R5576:Dnah9	UTSW	11	65,834,096 (GRCm38)	splice site	probably null
R5648:Dnah9	UTSW	11	65,927,755 (GRCm38)	missense	probably benign	0.00
R5653:Dnah9	UTSW	11	65,849,980 (GRCm38)	missense	probably damaging	0.99
R5713:Dnah9	UTSW	11	66,025,223 (GRCm38)	missense	possibly damaging	0.92
R5763:Dnah9	UTSW	11	65,955,239 (GRCm38)	missense	probably damaging	1.00
R5825:Dnah9	UTSW	11	66,126,601 (GRCm38)	missense	probably benign	0.01
R5831:Dnah9	UTSW	11	66,108,121 (GRCm38)	missense	probably benign	0.00
R5847:Dnah9	UTSW	11	66,095,240 (GRCm38)	frame shift	probably null
R5870:Dnah9	UTSW	11	66,085,210 (GRCm38)	missense	probably benign	0.01
R5902:Dnah9	UTSW	11	66,025,187 (GRCm38)	missense	probably benign	0.08
R5918:Dnah9	UTSW	11	65,834,199 (GRCm38)	missense	probably damaging	1.00
R5979:Dnah9	UTSW	11	65,834,481 (GRCm38)	missense	probably damaging	1.00
R6065:Dnah9	UTSW	11	66,145,397 (GRCm38)	missense	possibly damaging	0.65
R6065:Dnah9	UTSW	11	65,855,338 (GRCm38)	missense	probably benign	0.05
R6086:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
R6086:Dnah9	UTSW	11	65,989,915 (GRCm38)	missense	probably damaging	0.99
R6102:Dnah9	UTSW	11	65,990,516 (GRCm38)	missense	probably damaging	0.97
R6120:Dnah9	UTSW	11	66,147,399 (GRCm38)	missense	probably benign
R6154:Dnah9	UTSW	11	65,855,338 (GRCm38)	missense	probably benign	0.00
R6262:Dnah9	UTSW	11	65,881,805 (GRCm38)	splice site	probably null
R6265:Dnah9	UTSW	11	66,168,094 (GRCm38)	missense	probably benign	0.04
R6290:Dnah9	UTSW	11	65,841,375 (GRCm38)	missense	probably damaging	1.00
R6345:Dnah9	UTSW	11	66,037,693 (GRCm38)	missense	probably damaging	0.97
R6357:Dnah9	UTSW	11	65,874,196 (GRCm38)	missense	probably damaging	1.00
R6534:Dnah9	UTSW	11	65,955,248 (GRCm38)	missense	probably damaging	0.99
R6574:Dnah9	UTSW	11	66,168,281 (GRCm38)	missense	probably benign	0.37
R6582:Dnah9	UTSW	11	66,061,097 (GRCm38)	missense	probably damaging	1.00
R6700:Dnah9	UTSW	11	65,955,366 (GRCm38)	missense	probably damaging	1.00
R6800:Dnah9	UTSW	11	66,072,739 (GRCm38)	critical splice donor site	probably null
R6812:Dnah9	UTSW	11	65,981,329 (GRCm38)	missense	probably damaging	0.99
R6931:Dnah9	UTSW	11	66,117,626 (GRCm38)	missense	possibly damaging	0.63
R6944:Dnah9	UTSW	11	66,085,149 (GRCm38)	missense	possibly damaging	0.91
R6958:Dnah9	UTSW	11	66,076,341 (GRCm38)	missense	probably damaging	1.00
R6977:Dnah9	UTSW	11	66,107,909 (GRCm38)	missense	probably benign	0.37
R7021:Dnah9	UTSW	11	65,981,231 (GRCm38)	missense	probably benign
R7161:Dnah9	UTSW	11	65,855,372 (GRCm38)	nonsense	probably null
R7175:Dnah9	UTSW	11	66,133,637 (GRCm38)	missense	probably benign	0.03
R7199:Dnah9	UTSW	11	66,118,944 (GRCm38)	missense	probably benign	0.04
R7231:Dnah9	UTSW	11	65,965,647 (GRCm38)	missense	probably damaging	1.00
R7284:Dnah9	UTSW	11	65,990,476 (GRCm38)	missense	probably damaging	0.99
R7314:Dnah9	UTSW	11	65,989,851 (GRCm38)	missense	probably benign	0.00
R7350:Dnah9	UTSW	11	66,080,578 (GRCm38)	missense	probably damaging	1.00
R7420:Dnah9	UTSW	11	66,117,407 (GRCm38)	critical splice donor site	probably null
R7427:Dnah9	UTSW	11	65,955,219 (GRCm38)	missense	probably benign
R7477:Dnah9	UTSW	11	65,992,731 (GRCm38)	missense	probably damaging	0.98
R7515:Dnah9	UTSW	11	65,841,414 (GRCm38)	missense	probably benign	0.01
R7521:Dnah9	UTSW	11	65,989,837 (GRCm38)	missense	probably damaging	0.98
R7573:Dnah9	UTSW	11	66,125,215 (GRCm38)	missense	probably benign	0.43
R7659:Dnah9	UTSW	11	65,989,780 (GRCm38)	missense	probably damaging	0.99
R7707:Dnah9	UTSW	11	66,118,958 (GRCm38)	missense	probably damaging	1.00
R7749:Dnah9	UTSW	11	65,911,830 (GRCm38)	missense	probably damaging	1.00
R7792:Dnah9	UTSW	11	65,850,013 (GRCm38)	missense	probably damaging	1.00
R7808:Dnah9	UTSW	11	66,005,805 (GRCm38)	nonsense	probably null
R7814:Dnah9	UTSW	11	66,005,660 (GRCm38)	missense	probably damaging	1.00
R7818:Dnah9	UTSW	11	66,025,211 (GRCm38)	missense	possibly damaging	0.64
R7890:Dnah9	UTSW	11	66,072,072 (GRCm38)	missense	probably damaging	0.99
R7976:Dnah9	UTSW	11	65,841,401 (GRCm38)	missense	possibly damaging	0.91
R8121:Dnah9	UTSW	11	66,017,375 (GRCm38)	missense	probably benign	0.02
R8232:Dnah9	UTSW	11	65,855,323 (GRCm38)	missense	possibly damaging	0.91
R8311:Dnah9	UTSW	11	65,989,818 (GRCm38)	missense	probably benign	0.00
R8326:Dnah9	UTSW	11	66,117,626 (GRCm38)	missense	probably benign	0.01
R8338:Dnah9	UTSW	11	65,841,241 (GRCm38)	critical splice donor site	probably null
R8356:Dnah9	UTSW	11	66,156,938 (GRCm38)	missense	probably damaging	0.99
R8456:Dnah9	UTSW	11	66,156,938 (GRCm38)	missense	probably damaging	0.99
R8468:Dnah9	UTSW	11	65,831,730 (GRCm38)	missense	probably benign	0.00
R8721:Dnah9	UTSW	11	66,095,298 (GRCm38)	missense	probably damaging	1.00
R8747:Dnah9	UTSW	11	65,927,990 (GRCm38)	missense	possibly damaging	0.69
R8798:Dnah9	UTSW	11	65,905,231 (GRCm38)	missense	probably damaging	0.99
R8806:Dnah9	UTSW	11	65,859,483 (GRCm38)	missense	probably damaging	1.00
R8826:Dnah9	UTSW	11	65,849,916 (GRCm38)	missense	probably benign	0.13
R8837:Dnah9	UTSW	11	65,855,234 (GRCm38)	missense	possibly damaging	0.72
R8886:Dnah9	UTSW	11	66,053,014 (GRCm38)	missense	probably damaging	1.00
R8887:Dnah9	UTSW	11	65,855,384 (GRCm38)	missense	probably benign	0.01
R8921:Dnah9	UTSW	11	65,911,921 (GRCm38)	missense	probably benign
R8933:Dnah9	UTSW	11	65,855,252 (GRCm38)	missense	possibly damaging	0.88
R8949:Dnah9	UTSW	11	66,168,400 (GRCm38)	missense	possibly damaging	0.91
R8967:Dnah9	UTSW	11	66,125,112 (GRCm38)	critical splice donor site	probably null
R8979:Dnah9	UTSW	11	66,005,152 (GRCm38)	missense	probably benign
R8991:Dnah9	UTSW	11	65,886,680 (GRCm38)	missense	probably damaging	0.96
R9016:Dnah9	UTSW	11	66,108,030 (GRCm38)	missense	probably damaging	0.99
R9025:Dnah9	UTSW	11	66,005,825 (GRCm38)	missense	probably damaging	1.00
R9043:Dnah9	UTSW	11	65,954,854 (GRCm38)	missense
R9047:Dnah9	UTSW	11	66,072,099 (GRCm38)	missense	possibly damaging	0.89
R9076:Dnah9	UTSW	11	66,117,638 (GRCm38)	missense	probably benign	0.21
R9113:Dnah9	UTSW	11	65,989,887 (GRCm38)	missense	probably damaging	1.00
R9152:Dnah9	UTSW	11	66,130,631 (GRCm38)	missense	probably damaging	1.00
R9187:Dnah9	UTSW	11	66,005,146 (GRCm38)	missense	probably benign
R9198:Dnah9	UTSW	11	65,955,744 (GRCm38)	missense	probably benign	0.02
R9203:Dnah9	UTSW	11	65,855,287 (GRCm38)	missense	possibly damaging	0.58
R9234:Dnah9	UTSW	11	66,033,925 (GRCm38)	missense	possibly damaging	0.68
R9245:Dnah9	UTSW	11	65,895,905 (GRCm38)	missense	probably benign	0.30
R9265:Dnah9	UTSW	11	65,841,255 (GRCm38)	missense	probably benign	0.01
R9307:Dnah9	UTSW	11	66,085,474 (GRCm38)	missense	probably benign	0.14
R9336:Dnah9	UTSW	11	65,870,949 (GRCm38)	missense	probably damaging	1.00
R9386:Dnah9	UTSW	11	65,947,542 (GRCm38)	missense	probably damaging	1.00
R9498:Dnah9	UTSW	11	65,848,373 (GRCm38)	missense	probably damaging	0.99
R9508:Dnah9	UTSW	11	65,834,263 (GRCm38)	missense	probably damaging	1.00
R9524:Dnah9	UTSW	11	66,085,483 (GRCm38)	missense	possibly damaging	0.92
R9577:Dnah9	UTSW	11	65,976,521 (GRCm38)	missense	probably benign	0.00
R9583:Dnah9	UTSW	11	65,965,681 (GRCm38)	missense	probably damaging	1.00
R9587:Dnah9	UTSW	11	66,108,391 (GRCm38)	missense	probably null	0.92
R9612:Dnah9	UTSW	11	65,927,649 (GRCm38)	missense	probably benign	0.00
R9748:Dnah9	UTSW	11	66,085,464 (GRCm38)	missense	possibly damaging	0.51
R9749:Dnah9	UTSW	11	66,095,376 (GRCm38)	missense	probably damaging	1.00
R9759:Dnah9	UTSW	11	66,075,118 (GRCm38)	missense	probably null	0.93
R9784:Dnah9	UTSW	11	66,085,134 (GRCm38)	missense	probably damaging	0.99
V3553:Dnah9	UTSW	11	65,970,076 (GRCm38)	missense	probably damaging	1.00
X0027:Dnah9	UTSW	11	66,085,479 (GRCm38)	missense	probably benign	0.07
X0028:Dnah9	UTSW	11	65,990,452 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,970,084 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,927,853 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,895,972 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	66,072,835 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	66,037,474 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah9	UTSW	11	66,126,650 (GRCm38)	missense	probably damaging	1.00
Z1186:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1186:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1187:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1187:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1188:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1188:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1189:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1189:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1190:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1190:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1191:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1191:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1192:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1192:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TCAAGTGAGACAAGTCTTTGGGCAG -3'
(R):5'- AACTCTTCGCTCTCCAGACACAGG -3'

Sequencing Primer
(F):5'- TAGGGAAACACACATTTTACTCCTC -3'
(R):5'- TCCAGACACAGGGGTTCTATG -3'

Posted On

2013-04-16