Mutagenetix > Incidental Mutation

Incidental Mutation 'R2233:Fat3'

240182

Institutional Source

Beutler Lab

Gene Symbol

Fat3

Ensembl Gene

ENSMUSG00000074505

Gene Name

FAT atypical cadherin 3

Synonyms

D430038H04Rik, LOC382129, LOC234973, 9430076A06Rik

MMRRC Submission

040234-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.631) question?

Stock #

R2233 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

15821485-16412581 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 15909567 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Phenylalanine at position 2145 (S2145F)

Ref Sequence

ENSEMBL: ENSMUSP00000148968 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082170] [ENSMUST00000217308]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000082170
AA Change: S2145F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000080808
Gene: ENSMUSG00000074505
AA Change: S2145F

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
CA	65	151	3e-7	SMART
CA	175	259	8.9e-22	SMART
CA	280	368	8.9e-4	SMART
CA	389	465	2.6e-11	SMART
CA	489	571	2e-29	SMART
low complexity region	684	697	N/A	INTRINSIC
CA	743	824	1e-24	SMART
low complexity region	830	840	N/A	INTRINSIC
CA	848	929	7.6e-26	SMART
CA	953	1034	1.5e-25	SMART
CA	1060	1141	6.6e-32	SMART
CA	1165	1247	1.5e-30	SMART
CA	1273	1349	1.8e-8	SMART
CA	1375	1453	2.9e-12	SMART
CA	1477	1559	3e-22	SMART
CA	1583	1664	3.1e-16	SMART
CA	1688	1762	4.2e-22	SMART
CA	1793	1876	2.5e-26	SMART
CA	1900	1975	1.5e-8	SMART
low complexity region	1983	1994	N/A	INTRINSIC
CA	1999	2077	1.4e-18	SMART
CA	2101	2179	6.6e-10	SMART
CA	2203	2280	4.9e-19	SMART
CA	2304	2387	4.3e-29	SMART
CA	2411	2489	4.2e-11	SMART
CA	2513	2593	2.8e-22	SMART
CA	2617	2701	4.3e-10	SMART
CA	2719	2807	2.5e-7	SMART
CA	2831	2917	3.3e-27	SMART
CA	2941	3022	9.4e-23	SMART
CA	3046	3124	2.4e-26	SMART
CA	3148	3229	1.3e-32	SMART
CA	3253	3334	1.3e-29	SMART
CA	3358	3439	4.9e-28	SMART
CA	3463	3544	6.4e-12	SMART
EGF	3793	3828	1.3e-1	SMART
LamG	3852	3989	4.3e-25	SMART
EGF	4019	4053	2.7e-6	SMART
EGF	4058	4091	4.5e-6	SMART
EGF_CA	4093	4129	3.9e-11	SMART
transmembrane domain	4151	4170	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000217308
AA Change: S2145F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Meta Mutation Damage Score

0.2384

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 94.9%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozgyous for a knock-out allele exhibit abnormal amacrine cell differentiation and migration that result in the formation of two additional plexiform layers and thickened retinal ganglion layer. [provided by MGI curators]

Allele List at MGI

All alleles(3) : Gene trapped(3)

Other mutations in this stock

Total: 63 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam23	A	G	1: 63,584,671 (GRCm39)	I360V	probably benign	Het
Adarb1	A	G	10: 77,153,183 (GRCm39)	V322A	probably damaging	Het
Atad2b	T	G	12: 5,056,745 (GRCm39)	F867C	probably damaging	Het
Ccdc24	T	C	4: 117,727,113 (GRCm39)	K79R	possibly damaging	Het
Cfap44	A	G	16: 44,271,888 (GRCm39)	I1214V	probably benign	Het
Chrm4	A	G	2: 91,758,875 (GRCm39)	S428G	probably benign	Het
Chrnb1	A	T	11: 69,686,428 (GRCm39)	I64N	probably damaging	Het
Crh	A	T	3: 19,748,096 (GRCm39)	M182K	probably damaging	Het
Dazap1	A	G	10: 80,113,433 (GRCm39)	K110E	possibly damaging	Het
Dhx16	T	C	17: 36,198,778 (GRCm39)	C737R	probably damaging	Het
Dst	A	G	1: 34,313,343 (GRCm39)	E6384G	probably damaging	Het
Dync1i2	C	T	2: 71,079,764 (GRCm39)	Q419*	probably null	Het
E2f4	T	A	8: 106,025,283 (GRCm39)	V121E	probably damaging	Het
Enah	G	A	1: 181,749,537 (GRCm39)	P415L	probably damaging	Het
Fezf1	T	C	6: 23,246,002 (GRCm39)	T388A	probably damaging	Het
Gimap6	T	A	6: 48,681,418 (GRCm39)	H72L	possibly damaging	Het
Gm11149	A	G	9: 49,473,446 (GRCm39)		probably benign	Het
Gm12695	C	T	4: 96,612,266 (GRCm39)	R499Q	probably damaging	Het
Grhl1	A	G	12: 24,658,510 (GRCm39)	D385G	probably damaging	Het
Hyou1	C	T	9: 44,300,388 (GRCm39)	T855M	probably benign	Het
Igf1r	T	A	7: 67,861,828 (GRCm39)	N1129K	probably damaging	Het
Iglon5	T	C	7: 43,130,062 (GRCm39)	E34G	probably damaging	Het
Kcnab1	T	A	3: 65,226,888 (GRCm39)	V189D	probably damaging	Het
Kifap3	T	A	1: 163,683,634 (GRCm39)	D438E	probably benign	Het
Lmo2	T	C	2: 103,811,407 (GRCm39)	Y147H	probably damaging	Het
Lrrc41	G	A	4: 115,953,582 (GRCm39)	R756Q	possibly damaging	Het
Lrrc49	A	T	9: 60,505,440 (GRCm39)	F538L	possibly damaging	Het
Nphp3	G	A	9: 103,914,575 (GRCm39)	R1052H	probably benign	Het
Nynrin	G	A	14: 56,109,524 (GRCm39)	V1544I	possibly damaging	Het
Obscn	T	C	11: 59,022,472 (GRCm39)	R758G	possibly damaging	Het
Or6z5	T	C	7: 6,477,441 (GRCm39)	S111P	possibly damaging	Het
Or9m1	G	A	2: 87,733,819 (GRCm39)	S67F	probably damaging	Het
Osbpl6	T	C	2: 76,417,113 (GRCm39)	F577L	probably damaging	Het
Otc	A	G	X: 10,169,606 (GRCm39)	Q216R	probably benign	Het
Ppp1r12a	A	G	10: 108,034,780 (GRCm39)	I108M	possibly damaging	Het
Prl7a1	C	A	13: 27,826,402 (GRCm39)		probably null	Het
Prss16	T	C	13: 22,193,579 (GRCm39)	D72G	possibly damaging	Het
Qrsl1	T	C	10: 43,772,092 (GRCm39)	K33E	probably benign	Het
Rabepk	A	T	2: 34,685,246 (GRCm39)	I58N	possibly damaging	Het
Ralgapa1	A	T	12: 55,763,856 (GRCm39)	H1403Q	probably benign	Het
Rhobtb3	C	A	13: 76,020,484 (GRCm39)	C606F	possibly damaging	Het
Rnf216	G	A	5: 143,076,681 (GRCm39)	H68Y	probably benign	Het
Scap	T	C	9: 110,210,661 (GRCm39)	C998R	probably damaging	Het
Scgb1b27	T	C	7: 33,721,249 (GRCm39)	Y46H	probably damaging	Het
Sel1l2	T	C	2: 140,086,085 (GRCm39)	Y502C	probably damaging	Het
Sf3a2	G	T	10: 80,638,663 (GRCm39)	A95S	probably benign	Het
Sis	A	T	3: 72,820,527 (GRCm39)	F1412L	probably benign	Het
Slc25a29	A	T	12: 108,801,587 (GRCm39)	C9S	possibly damaging	Het
Snap91	T	C	9: 86,680,624 (GRCm39)	T427A	probably benign	Het
St3gal6	A	G	16: 58,293,897 (GRCm39)	F211L	probably damaging	Het
Stab1	G	A	14: 30,883,837 (GRCm39)	S240F	probably benign	Het
Sun3	T	A	11: 8,973,371 (GRCm39)	K109*	probably null	Het
Syne1	T	C	10: 4,991,484 (GRCm39)	N8410S	probably benign	Het
Tbx18	G	T	9: 87,606,403 (GRCm39)	S247R	probably damaging	Het
Tenm3	T	C	8: 48,729,204 (GRCm39)	I1601V	probably benign	Het
Tmem135	T	C	7: 88,803,282 (GRCm39)	N297S	probably damaging	Het
Tnk1	C	T	11: 69,746,017 (GRCm39)		probably null	Het
Txnl4b	A	G	8: 110,295,551 (GRCm39)		probably benign	Het
Uck1	T	C	2: 32,148,315 (GRCm39)	D167G	probably damaging	Het
Vmn2r124	A	T	17: 18,269,927 (GRCm39)	H61L	possibly damaging	Het
Xylt2	C	T	11: 94,560,822 (GRCm39)	V239M	possibly damaging	Het
Zmpste24	T	C	4: 120,955,162 (GRCm39)	D12G	probably benign	Het
Zscan25	A	G	5: 145,220,502 (GRCm39)	Y99C	probably damaging	Het

Other mutations in Fat3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00662:Fat3	APN	9	15,907,723 (GRCm39)	missense	possibly damaging	0.77
IGL00962:Fat3	APN	9	15,826,815 (GRCm39)	missense	probably benign	0.14
IGL00966:Fat3	APN	9	15,910,390 (GRCm39)	missense	possibly damaging	0.69
IGL01100:Fat3	APN	9	16,286,524 (GRCm39)	missense	probably damaging	1.00
IGL01104:Fat3	APN	9	16,287,024 (GRCm39)	missense	possibly damaging	0.92
IGL01104:Fat3	APN	9	15,909,756 (GRCm39)	missense	probably damaging	1.00
IGL01121:Fat3	APN	9	15,909,697 (GRCm39)	missense	probably benign	0.00
IGL01407:Fat3	APN	9	16,289,319 (GRCm39)	missense	probably benign	0.01
IGL01444:Fat3	APN	9	15,910,144 (GRCm39)	missense	probably damaging	1.00
IGL01634:Fat3	APN	9	15,909,654 (GRCm39)	missense	probably damaging	1.00
IGL01649:Fat3	APN	9	16,288,015 (GRCm39)	missense	possibly damaging	0.95
IGL01839:Fat3	APN	9	15,909,168 (GRCm39)	missense	probably damaging	1.00
IGL01867:Fat3	APN	9	16,289,197 (GRCm39)	missense	probably benign	0.03
IGL01894:Fat3	APN	9	16,287,145 (GRCm39)	missense	probably benign
IGL01913:Fat3	APN	9	15,910,086 (GRCm39)	missense	probably damaging	0.99
IGL02033:Fat3	APN	9	15,826,648 (GRCm39)	missense	possibly damaging	0.50
IGL02035:Fat3	APN	9	16,289,266 (GRCm39)	missense	probably benign	0.06
IGL02146:Fat3	APN	9	15,910,878 (GRCm39)	missense	probably benign
IGL02147:Fat3	APN	9	15,907,281 (GRCm39)	missense	probably damaging	1.00
IGL02161:Fat3	APN	9	15,908,346 (GRCm39)	missense	probably benign	0.10
IGL02161:Fat3	APN	9	15,908,347 (GRCm39)	nonsense	probably null
IGL02164:Fat3	APN	9	15,942,720 (GRCm39)	splice site	probably benign
IGL02269:Fat3	APN	9	15,826,873 (GRCm39)	missense	possibly damaging	0.84
IGL02314:Fat3	APN	9	15,881,134 (GRCm39)	missense	possibly damaging	0.61
IGL02393:Fat3	APN	9	15,899,708 (GRCm39)	nonsense	probably null
IGL02410:Fat3	APN	9	15,909,141 (GRCm39)	missense	probably damaging	1.00
IGL02504:Fat3	APN	9	15,871,094 (GRCm39)	missense	probably damaging	1.00
IGL02572:Fat3	APN	9	15,871,802 (GRCm39)	missense	probably benign
IGL02623:Fat3	APN	9	15,908,433 (GRCm39)	missense	probably damaging	1.00
IGL02654:Fat3	APN	9	15,908,271 (GRCm39)	missense	possibly damaging	0.84
IGL02749:Fat3	APN	9	15,918,007 (GRCm39)	missense	possibly damaging	0.93
IGL02810:Fat3	APN	9	16,288,146 (GRCm39)	missense	probably damaging	1.00
IGL02839:Fat3	APN	9	15,830,466 (GRCm39)	missense	probably damaging	1.00
IGL02890:Fat3	APN	9	15,826,636 (GRCm39)	missense	probably benign	0.03
IGL02892:Fat3	APN	9	16,288,858 (GRCm39)	missense	probably damaging	1.00
IGL03090:Fat3	APN	9	16,288,535 (GRCm39)	nonsense	probably null
IGL03144:Fat3	APN	9	16,286,541 (GRCm39)	missense	probably damaging	1.00
IGL03199:Fat3	APN	9	16,288,344 (GRCm39)	missense	possibly damaging	0.83
IGL03365:Fat3	APN	9	15,907,765 (GRCm39)	missense	probably damaging	1.00
IGL03392:Fat3	APN	9	15,915,158 (GRCm39)	missense	probably benign
IGL03408:Fat3	APN	9	15,909,253 (GRCm39)	nonsense	probably null
gagged	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
hushed	UTSW	9	15,871,165 (GRCm39)	missense	possibly damaging	0.72
Muffled	UTSW	9	15,849,287 (GRCm39)	critical splice donor site	probably null
muted	UTSW	9	15,908,773 (GRCm39)	missense	possibly damaging	0.93
Softened	UTSW	9	16,289,481 (GRCm39)	missense	probably benign
BB001:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
BB002:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
BB011:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
BB012:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
F6893:Fat3	UTSW	9	15,918,085 (GRCm39)	missense	probably damaging	0.99
IGL03050:Fat3	UTSW	9	15,907,896 (GRCm39)	missense	probably benign	0.04
PIT4142001:Fat3	UTSW	9	15,903,414 (GRCm39)	critical splice donor site	probably null
PIT4283001:Fat3	UTSW	9	15,917,897 (GRCm39)	missense	possibly damaging	0.77
PIT4378001:Fat3	UTSW	9	16,288,104 (GRCm39)	missense	probably benign	0.05
PIT4434001:Fat3	UTSW	9	15,907,612 (GRCm39)	missense	probably benign	0.00
PIT4468001:Fat3	UTSW	9	15,907,647 (GRCm39)	missense	probably benign	0.06
R0001:Fat3	UTSW	9	16,289,169 (GRCm39)	missense	probably damaging	0.99
R0005:Fat3	UTSW	9	15,874,162 (GRCm39)	missense	probably damaging	1.00
R0005:Fat3	UTSW	9	15,874,162 (GRCm39)	missense	probably damaging	1.00
R0038:Fat3	UTSW	9	15,826,306 (GRCm39)	missense	probably damaging	1.00
R0046:Fat3	UTSW	9	15,877,275 (GRCm39)	missense	possibly damaging	0.65
R0089:Fat3	UTSW	9	15,849,501 (GRCm39)	missense	probably benign
R0135:Fat3	UTSW	9	15,918,073 (GRCm39)	missense	probably damaging	1.00
R0255:Fat3	UTSW	9	15,881,002 (GRCm39)	splice site	probably benign
R0349:Fat3	UTSW	9	15,942,476 (GRCm39)	missense	probably damaging	1.00
R0361:Fat3	UTSW	9	15,909,699 (GRCm39)	missense	possibly damaging	0.77
R0382:Fat3	UTSW	9	15,871,052 (GRCm39)	missense	probably damaging	1.00
R0418:Fat3	UTSW	9	16,158,192 (GRCm39)	missense	probably damaging	1.00
R0419:Fat3	UTSW	9	15,903,552 (GRCm39)	missense	probably damaging	1.00
R0437:Fat3	UTSW	9	15,908,228 (GRCm39)	missense	probably damaging	1.00
R0441:Fat3	UTSW	9	15,856,304 (GRCm39)	splice site	probably benign
R0480:Fat3	UTSW	9	15,909,025 (GRCm39)	missense	probably benign	0.00
R0510:Fat3	UTSW	9	15,910,981 (GRCm39)	nonsense	probably null
R0665:Fat3	UTSW	9	15,908,698 (GRCm39)	missense	probably benign
R0715:Fat3	UTSW	9	16,286,419 (GRCm39)	missense	probably benign
R0727:Fat3	UTSW	9	15,907,995 (GRCm39)	missense	probably damaging	1.00
R0882:Fat3	UTSW	9	15,942,664 (GRCm39)	missense	possibly damaging	0.84
R0946:Fat3	UTSW	9	15,909,100 (GRCm39)	missense	possibly damaging	0.95
R1068:Fat3	UTSW	9	15,881,330 (GRCm39)	missense	probably benign
R1081:Fat3	UTSW	9	16,286,580 (GRCm39)	missense	possibly damaging	0.62
R1082:Fat3	UTSW	9	15,917,911 (GRCm39)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,908,070 (GRCm39)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,908,070 (GRCm39)	missense	probably damaging	1.00
R1233:Fat3	UTSW	9	15,834,041 (GRCm39)	missense	probably benign
R1306:Fat3	UTSW	9	16,287,975 (GRCm39)	missense	probably damaging	1.00
R1311:Fat3	UTSW	9	15,932,706 (GRCm39)	missense	probably damaging	1.00
R1338:Fat3	UTSW	9	15,836,387 (GRCm39)	missense	probably benign	0.00
R1395:Fat3	UTSW	9	16,158,212 (GRCm39)	missense	probably benign	0.00
R1466:Fat3	UTSW	9	16,286,778 (GRCm39)	missense	probably damaging	0.96
R1466:Fat3	UTSW	9	16,286,778 (GRCm39)	missense	probably damaging	0.96
R1510:Fat3	UTSW	9	15,871,351 (GRCm39)	missense	probably damaging	1.00
R1528:Fat3	UTSW	9	15,836,387 (GRCm39)	missense	probably benign	0.00
R1531:Fat3	UTSW	9	15,908,761 (GRCm39)	missense	probably damaging	1.00
R1659:Fat3	UTSW	9	15,908,479 (GRCm39)	missense	possibly damaging	0.91
R1697:Fat3	UTSW	9	15,856,176 (GRCm39)	missense	probably benign	0.05
R1699:Fat3	UTSW	9	15,849,694 (GRCm39)	missense	probably damaging	1.00
R1728:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1729:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1731:Fat3	UTSW	9	15,907,233 (GRCm39)	missense	probably benign
R1784:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1789:Fat3	UTSW	9	16,288,281 (GRCm39)	missense	probably benign	0.00
R1794:Fat3	UTSW	9	15,908,434 (GRCm39)	missense	probably benign	0.15
R1794:Fat3	UTSW	9	15,908,432 (GRCm39)	nonsense	probably null
R1830:Fat3	UTSW	9	15,826,636 (GRCm39)	missense	probably benign	0.03
R1835:Fat3	UTSW	9	15,909,384 (GRCm39)	missense	probably damaging	1.00
R1887:Fat3	UTSW	9	15,878,357 (GRCm39)	missense	probably damaging	1.00
R1898:Fat3	UTSW	9	15,871,426 (GRCm39)	missense	probably damaging	1.00
R1909:Fat3	UTSW	9	15,909,411 (GRCm39)	missense	probably benign
R1912:Fat3	UTSW	9	15,881,284 (GRCm39)	missense	probably damaging	1.00
R1917:Fat3	UTSW	9	15,908,353 (GRCm39)	missense	possibly damaging	0.55
R1967:Fat3	UTSW	9	15,879,591 (GRCm39)	missense	probably benign	0.00
R2070:Fat3	UTSW	9	15,910,666 (GRCm39)	missense	probably benign	0.21
R2100:Fat3	UTSW	9	16,288,726 (GRCm39)	missense	possibly damaging	0.73
R2104:Fat3	UTSW	9	15,909,813 (GRCm39)	missense	possibly damaging	0.77
R2113:Fat3	UTSW	9	15,911,082 (GRCm39)	missense	probably damaging	1.00
R2132:Fat3	UTSW	9	16,158,015 (GRCm39)	critical splice donor site	probably null
R2136:Fat3	UTSW	9	16,288,347 (GRCm39)	missense	probably benign	0.01
R2146:Fat3	UTSW	9	15,901,808 (GRCm39)	missense	probably benign	0.01
R2234:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2273:Fat3	UTSW	9	15,826,558 (GRCm39)	missense	probably benign
R2285:Fat3	UTSW	9	16,287,469 (GRCm39)	missense	probably damaging	1.00
R2363:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2365:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2367:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2403:Fat3	UTSW	9	15,881,167 (GRCm39)	missense	probably damaging	1.00
R2447:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2496:Fat3	UTSW	9	15,877,399 (GRCm39)	missense	probably benign	0.01
R2509:Fat3	UTSW	9	15,836,310 (GRCm39)	missense	possibly damaging	0.82
R2932:Fat3	UTSW	9	16,287,240 (GRCm39)	missense	probably damaging	1.00
R2986:Fat3	UTSW	9	15,903,424 (GRCm39)	missense	probably damaging	1.00
R3054:Fat3	UTSW	9	15,871,792 (GRCm39)	missense	probably benign
R3056:Fat3	UTSW	9	15,871,792 (GRCm39)	missense	probably benign
R3729:Fat3	UTSW	9	16,158,337 (GRCm39)	splice site	probably benign
R3745:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3806:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3859:Fat3	UTSW	9	15,908,524 (GRCm39)	nonsense	probably null
R3862:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3890:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3892:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3950:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3972:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4004:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4005:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4086:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4111:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4113:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4227:Fat3	UTSW	9	16,288,989 (GRCm39)	missense	probably damaging	1.00
R4352:Fat3	UTSW	9	16,158,074 (GRCm39)	missense	possibly damaging	0.55
R4394:Fat3	UTSW	9	15,834,088 (GRCm39)	missense	probably benign	0.11
R4403:Fat3	UTSW	9	15,856,169 (GRCm39)	missense	probably damaging	1.00
R4433:Fat3	UTSW	9	15,942,448 (GRCm39)	missense	probably damaging	0.99
R4453:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4479:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4480:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4521:Fat3	UTSW	9	15,834,238 (GRCm39)	missense	probably null	0.71
R4620:Fat3	UTSW	9	15,908,190 (GRCm39)	missense	probably damaging	1.00
R4700:Fat3	UTSW	9	15,942,469 (GRCm39)	missense	probably damaging	1.00
R4721:Fat3	UTSW	9	15,941,262 (GRCm39)	missense	probably damaging	1.00
R4790:Fat3	UTSW	9	15,909,780 (GRCm39)	missense	probably damaging	1.00
R4796:Fat3	UTSW	9	15,911,028 (GRCm39)	missense	probably benign	0.17
R4823:Fat3	UTSW	9	15,907,803 (GRCm39)	missense	probably benign
R4836:Fat3	UTSW	9	16,289,019 (GRCm39)	missense	probably damaging	1.00
R4842:Fat3	UTSW	9	15,908,883 (GRCm39)	missense	probably damaging	1.00
R4849:Fat3	UTSW	9	16,289,244 (GRCm39)	missense	probably benign	0.03
R4856:Fat3	UTSW	9	15,932,626 (GRCm39)	missense	probably benign
R4869:Fat3	UTSW	9	16,288,773 (GRCm39)	missense	probably damaging	0.98
R4886:Fat3	UTSW	9	15,932,626 (GRCm39)	missense	probably benign
R4899:Fat3	UTSW	9	15,881,095 (GRCm39)	missense	probably damaging	1.00
R4941:Fat3	UTSW	9	16,286,448 (GRCm39)	missense	probably damaging	1.00
R4986:Fat3	UTSW	9	15,909,636 (GRCm39)	missense	probably damaging	1.00
R5058:Fat3	UTSW	9	15,908,154 (GRCm39)	missense	probably damaging	1.00
R5079:Fat3	UTSW	9	15,910,423 (GRCm39)	missense	probably benign	0.01
R5080:Fat3	UTSW	9	15,910,634 (GRCm39)	missense	probably benign	0.35
R5174:Fat3	UTSW	9	15,910,866 (GRCm39)	missense	probably damaging	1.00
R5183:Fat3	UTSW	9	15,871,609 (GRCm39)	missense	probably damaging	0.99
R5203:Fat3	UTSW	9	16,289,438 (GRCm39)	missense	possibly damaging	0.79
R5216:Fat3	UTSW	9	16,288,833 (GRCm39)	missense	probably damaging	1.00
R5230:Fat3	UTSW	9	15,901,856 (GRCm39)	missense	possibly damaging	0.51
R5318:Fat3	UTSW	9	16,287,925 (GRCm39)	missense	probably damaging	1.00
R5377:Fat3	UTSW	9	16,287,739 (GRCm39)	missense	probably benign	0.05
R5385:Fat3	UTSW	9	15,833,971 (GRCm39)	missense	possibly damaging	0.82
R5436:Fat3	UTSW	9	15,871,810 (GRCm39)	missense	probably benign	0.02
R5437:Fat3	UTSW	9	15,996,604 (GRCm39)	missense	probably damaging	1.00
R5453:Fat3	UTSW	9	15,908,160 (GRCm39)	missense	probably damaging	1.00
R5460:Fat3	UTSW	9	15,830,463 (GRCm39)	missense	probably damaging	1.00
R5516:Fat3	UTSW	9	15,910,005 (GRCm39)	missense	probably damaging	1.00
R5568:Fat3	UTSW	9	16,288,219 (GRCm39)	nonsense	probably null
R5628:Fat3	UTSW	9	15,877,392 (GRCm39)	missense	probably damaging	1.00
R5835:Fat3	UTSW	9	16,287,129 (GRCm39)	missense	probably damaging	1.00
R5845:Fat3	UTSW	9	16,288,506 (GRCm39)	missense	probably damaging	1.00
R5898:Fat3	UTSW	9	15,849,757 (GRCm39)	missense	probably benign	0.15
R5941:Fat3	UTSW	9	15,910,797 (GRCm39)	missense	probably benign	0.07
R5974:Fat3	UTSW	9	15,917,824 (GRCm39)	critical splice donor site	probably null
R5986:Fat3	UTSW	9	15,909,613 (GRCm39)	missense	probably benign	0.22
R6015:Fat3	UTSW	9	16,287,346 (GRCm39)	missense	possibly damaging	0.55
R6031:Fat3	UTSW	9	15,899,788 (GRCm39)	missense	probably benign	0.02
R6031:Fat3	UTSW	9	15,899,788 (GRCm39)	missense	probably benign	0.02
R6042:Fat3	UTSW	9	16,289,113 (GRCm39)	missense	probably benign	0.12
R6051:Fat3	UTSW	9	16,286,751 (GRCm39)	missense	possibly damaging	0.83
R6052:Fat3	UTSW	9	15,833,975 (GRCm39)	missense	probably null
R6119:Fat3	UTSW	9	16,287,864 (GRCm39)	missense	possibly damaging	0.82
R6161:Fat3	UTSW	9	16,288,818 (GRCm39)	missense	probably damaging	1.00
R6254:Fat3	UTSW	9	15,907,441 (GRCm39)	missense	probably benign	0.19
R6318:Fat3	UTSW	9	15,828,280 (GRCm39)	intron	probably benign
R6347:Fat3	UTSW	9	15,909,668 (GRCm39)	missense	probably damaging	1.00
R6348:Fat3	UTSW	9	15,849,287 (GRCm39)	critical splice donor site	probably null
R6351:Fat3	UTSW	9	15,849,694 (GRCm39)	missense	probably damaging	1.00
R6450:Fat3	UTSW	9	15,910,466 (GRCm39)	missense	possibly damaging	0.51
R6460:Fat3	UTSW	9	15,878,296 (GRCm39)	missense	probably damaging	1.00
R6524:Fat3	UTSW	9	15,903,552 (GRCm39)	missense	probably damaging	1.00
R6533:Fat3	UTSW	9	15,910,195 (GRCm39)	missense	probably benign	0.02
R6565:Fat3	UTSW	9	15,826,623 (GRCm39)	missense	probably benign
R6576:Fat3	UTSW	9	16,288,506 (GRCm39)	missense	probably damaging	1.00
R6649:Fat3	UTSW	9	16,288,038 (GRCm39)	missense	probably damaging	1.00
R6716:Fat3	UTSW	9	15,830,565 (GRCm39)	missense	probably benign
R6719:Fat3	UTSW	9	15,907,440 (GRCm39)	missense	probably benign
R6753:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6754:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6755:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6792:Fat3	UTSW	9	16,286,940 (GRCm39)	missense	probably damaging	1.00
R6802:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6803:Fat3	UTSW	9	15,908,083 (GRCm39)	missense	probably damaging	0.99
R6831:Fat3	UTSW	9	16,287,847 (GRCm39)	missense	probably damaging	0.98
R6831:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6833:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6877:Fat3	UTSW	9	15,910,564 (GRCm39)	missense	probably benign
R6894:Fat3	UTSW	9	15,909,072 (GRCm39)	missense	probably damaging	1.00
R6915:Fat3	UTSW	9	16,289,044 (GRCm39)	missense	probably benign	0.37
R6931:Fat3	UTSW	9	15,871,238 (GRCm39)	missense	possibly damaging	0.89
R6934:Fat3	UTSW	9	16,288,252 (GRCm39)	missense	probably damaging	0.98
R6940:Fat3	UTSW	9	15,828,096 (GRCm39)	splice site	probably null
R6959:Fat3	UTSW	9	15,908,181 (GRCm39)	missense	possibly damaging	0.91
R6969:Fat3	UTSW	9	15,941,212 (GRCm39)	missense	probably benign	0.29
R6986:Fat3	UTSW	9	15,932,631 (GRCm39)	missense	probably damaging	1.00
R6993:Fat3	UTSW	9	15,830,517 (GRCm39)	missense	probably damaging	1.00
R7039:Fat3	UTSW	9	16,287,561 (GRCm39)	missense	probably damaging	1.00
R7051:Fat3	UTSW	9	16,289,123 (GRCm39)	missense	probably damaging	1.00
R7089:Fat3	UTSW	9	15,908,214 (GRCm39)	missense	probably benign	0.01
R7136:Fat3	UTSW	9	16,289,481 (GRCm39)	missense	probably benign
R7137:Fat3	UTSW	9	15,908,444 (GRCm39)	missense	probably damaging	1.00
R7154:Fat3	UTSW	9	15,908,160 (GRCm39)	missense	probably damaging	1.00
R7170:Fat3	UTSW	9	15,917,870 (GRCm39)	missense	probably damaging	0.99
R7183:Fat3	UTSW	9	15,834,133 (GRCm39)	missense	possibly damaging	0.81
R7237:Fat3	UTSW	9	16,288,510 (GRCm39)	missense	probably damaging	1.00
R7288:Fat3	UTSW	9	15,909,888 (GRCm39)	missense	probably damaging	1.00
R7293:Fat3	UTSW	9	15,826,592 (GRCm39)	missense
R7293:Fat3	UTSW	9	15,826,336 (GRCm39)	missense
R7381:Fat3	UTSW	9	16,158,283 (GRCm39)	missense	probably damaging	1.00
R7438:Fat3	UTSW	9	15,899,778 (GRCm39)	missense	probably benign
R7537:Fat3	UTSW	9	15,849,615 (GRCm39)	missense	probably damaging	1.00
R7560:Fat3	UTSW	9	15,908,138 (GRCm39)	missense	probably damaging	1.00
R7585:Fat3	UTSW	9	15,909,558 (GRCm39)	missense	probably benign	0.03
R7623:Fat3	UTSW	9	15,899,620 (GRCm39)	missense	probably damaging	1.00
R7624:Fat3	UTSW	9	15,871,165 (GRCm39)	missense	possibly damaging	0.72
R7684:Fat3	UTSW	9	15,899,564 (GRCm39)	critical splice donor site	probably null
R7690:Fat3	UTSW	9	15,909,477 (GRCm39)	missense	probably damaging	1.00
R7804:Fat3	UTSW	9	15,901,888 (GRCm39)	missense	probably benign	0.01
R7809:Fat3	UTSW	9	15,917,924 (GRCm39)	missense	probably damaging	1.00
R7924:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
R7925:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
R7954:Fat3	UTSW	9	15,909,708 (GRCm39)	missense	probably damaging	1.00
R8021:Fat3	UTSW	9	15,910,405 (GRCm39)	missense	probably damaging	0.99
R8118:Fat3	UTSW	9	15,871,400 (GRCm39)	missense	probably benign
R8141:Fat3	UTSW	9	15,908,362 (GRCm39)	missense	possibly damaging	0.79
R8163:Fat3	UTSW	9	15,871,055 (GRCm39)	missense	probably damaging	1.00
R8170:Fat3	UTSW	9	15,858,792 (GRCm39)	missense	probably damaging	0.97
R8201:Fat3	UTSW	9	15,908,773 (GRCm39)	missense	possibly damaging	0.93
R8258:Fat3	UTSW	9	15,901,887 (GRCm39)	missense	possibly damaging	0.79
R8259:Fat3	UTSW	9	15,901,887 (GRCm39)	missense	possibly damaging	0.79
R8274:Fat3	UTSW	9	16,288,786 (GRCm39)	nonsense	probably null
R8275:Fat3	UTSW	9	16,158,046 (GRCm39)	missense	probably damaging	1.00
R8345:Fat3	UTSW	9	15,910,570 (GRCm39)	missense	probably benign	0.08
R8350:Fat3	UTSW	9	15,826,435 (GRCm39)	missense
R8405:Fat3	UTSW	9	15,907,167 (GRCm39)	missense	probably damaging	1.00
R8421:Fat3	UTSW	9	15,909,480 (GRCm39)	missense	probably damaging	1.00
R8450:Fat3	UTSW	9	15,826,435 (GRCm39)	missense
R8472:Fat3	UTSW	9	16,286,563 (GRCm39)	missense	possibly damaging	0.90
R8482:Fat3	UTSW	9	16,158,263 (GRCm39)	missense	probably benign	0.02
R8680:Fat3	UTSW	9	15,908,703 (GRCm39)	missense	probably damaging	0.99
R8690:Fat3	UTSW	9	15,878,397 (GRCm39)	missense	probably benign	0.45
R8748:Fat3	UTSW	9	15,834,161 (GRCm39)	missense	possibly damaging	0.70
R8756:Fat3	UTSW	9	16,287,885 (GRCm39)	missense	probably damaging	1.00
R8834:Fat3	UTSW	9	15,942,493 (GRCm39)	missense	probably damaging	1.00
R8848:Fat3	UTSW	9	15,878,398 (GRCm39)	missense	probably damaging	1.00
R8884:Fat3	UTSW	9	15,941,280 (GRCm39)	missense	probably damaging	1.00
R8898:Fat3	UTSW	9	15,858,822 (GRCm39)	missense	probably benign	0.04
R8930:Fat3	UTSW	9	15,910,819 (GRCm39)	missense	probably benign	0.06
R8932:Fat3	UTSW	9	15,910,819 (GRCm39)	missense	probably benign	0.06
R8954:Fat3	UTSW	9	16,287,864 (GRCm39)	missense	probably benign	0.00
R8995:Fat3	UTSW	9	16,286,898 (GRCm39)	missense	probably damaging	1.00
R9000:Fat3	UTSW	9	15,918,095 (GRCm39)	missense	probably benign	0.12
R9000:Fat3	UTSW	9	15,871,816 (GRCm39)	missense	possibly damaging	0.82
R9060:Fat3	UTSW	9	15,910,782 (GRCm39)	missense	possibly damaging	0.80
R9116:Fat3	UTSW	9	15,909,421 (GRCm39)	missense	probably benign	0.34
R9136:Fat3	UTSW	9	15,833,738 (GRCm39)	missense
R9193:Fat3	UTSW	9	15,910,248 (GRCm39)	missense	probably benign
R9235:Fat3	UTSW	9	15,833,674 (GRCm39)	missense	probably null
R9257:Fat3	UTSW	9	15,907,863 (GRCm39)	missense	probably benign
R9297:Fat3	UTSW	9	15,908,996 (GRCm39)	missense	probably damaging	1.00
R9307:Fat3	UTSW	9	15,932,719 (GRCm39)	missense	probably damaging	1.00
R9412:Fat3	UTSW	9	15,908,703 (GRCm39)	missense	probably damaging	0.99
R9427:Fat3	UTSW	9	16,288,691 (GRCm39)	nonsense	probably null
R9430:Fat3	UTSW	9	16,287,381 (GRCm39)	missense	probably damaging	1.00
R9480:Fat3	UTSW	9	15,942,703 (GRCm39)	missense	probably damaging	1.00
R9497:Fat3	UTSW	9	15,903,504 (GRCm39)	missense	probably damaging	0.99
R9547:Fat3	UTSW	9	15,911,142 (GRCm39)	missense	possibly damaging	0.86
R9569:Fat3	UTSW	9	15,830,495 (GRCm39)	missense
R9591:Fat3	UTSW	9	16,288,336 (GRCm39)	missense	probably benign	0.01
R9615:Fat3	UTSW	9	16,289,343 (GRCm39)	missense	probably benign	0.00
R9649:Fat3	UTSW	9	15,908,054 (GRCm39)	missense	possibly damaging	0.57
R9671:Fat3	UTSW	9	16,286,871 (GRCm39)	missense	possibly damaging	0.93
R9750:Fat3	UTSW	9	15,915,157 (GRCm39)	missense	probably benign	0.00
R9777:Fat3	UTSW	9	15,826,537 (GRCm39)	missense	probably benign
RF006:Fat3	UTSW	9	15,909,913 (GRCm39)	missense	probably benign	0.36
X0021:Fat3	UTSW	9	15,941,227 (GRCm39)	missense	probably null	0.66
X0026:Fat3	UTSW	9	15,907,629 (GRCm39)	missense	probably benign
X0064:Fat3	UTSW	9	15,830,573 (GRCm39)	missense	probably benign
Z1176:Fat3	UTSW	9	16,286,913 (GRCm39)	missense	probably benign
Z1176:Fat3	UTSW	9	16,286,725 (GRCm39)	missense	probably damaging	1.00
Z1176:Fat3	UTSW	9	15,858,822 (GRCm39)	missense	probably damaging	0.98
Z1177:Fat3	UTSW	9	15,877,287 (GRCm39)	missense	possibly damaging	0.68
Z1177:Fat3	UTSW	9	15,858,834 (GRCm39)	missense	probably damaging	1.00
Z1177:Fat3	UTSW	9	15,834,322 (GRCm39)	missense	possibly damaging	0.81
Z1177:Fat3	UTSW	9	15,881,131 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- AGGGATCTCCATCGATGATGAGG -3'
(R):5'- CAAGTTGATGCTGAGCCAGG -3'

Sequencing Primer
(F):5'- CATCGATGATGAGGTATATGATGCCC -3'
(R):5'- TGCTGAGCCAGGAACTCTGATATAC -3'

Posted On

2014-10-15