Incidental Mutation 'R2249:Zfp142'
| ID |
240752 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp142
|
| Ensembl Gene |
ENSMUSG00000026135 |
| Gene Name |
zinc finger protein 142 |
| Synonyms |
9330177B18Rik |
| MMRRC Submission |
040249-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2249 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
74605490-74627308 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 74606191 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1793
(V1793A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000027315
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027315]
[ENSMUST00000027362]
[ENSMUST00000066986]
[ENSMUST00000067916]
[ENSMUST00000113737]
[ENSMUST00000113747]
[ENSMUST00000113749]
[ENSMUST00000141412]
[ENSMUST00000127921]
[ENSMUST00000156613]
[ENSMUST00000113750]
[ENSMUST00000152707]
|
| AlphaFold |
G5E869 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000027315
AA Change: V1793A
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000027315
Gene: ENSMUSG00000026135
AA Change: V1793A
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
103 |
127 |
1.16e1 |
SMART |
|
ZnF_C2H2
|
164 |
186 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
193 |
218 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
223 |
247 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
250 |
272 |
9.96e-1 |
SMART |
|
low complexity region
|
317 |
329 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
363 |
385 |
9.96e-1 |
SMART |
|
ZnF_C2H2
|
391 |
411 |
1.26e1 |
SMART |
|
ZnF_C2H2
|
419 |
442 |
1.47e-3 |
SMART |
|
ZnF_C2H2
|
453 |
475 |
2.75e-3 |
SMART |
|
ZnF_C2H2
|
486 |
511 |
3.34e-2 |
SMART |
|
ZnF_C2H2
|
516 |
540 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
543 |
566 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
572 |
595 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
601 |
623 |
1.56e-2 |
SMART |
|
ZnF_C2H2
|
629 |
651 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
657 |
679 |
1.38e-3 |
SMART |
|
ZnF_C2H2
|
685 |
707 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
712 |
735 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
744 |
767 |
1.31e0 |
SMART |
|
ZnF_C2H2
|
773 |
796 |
2.63e0 |
SMART |
|
low complexity region
|
903 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
953 |
969 |
N/A |
INTRINSIC |
|
low complexity region
|
996 |
1007 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1039 |
1059 |
2.01e1 |
SMART |
|
ZnF_C2H2
|
1069 |
1089 |
1.91e1 |
SMART |
|
low complexity region
|
1147 |
1160 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1187 |
1207 |
2.7e2 |
SMART |
|
low complexity region
|
1209 |
1222 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1265 |
1285 |
3.56e1 |
SMART |
|
ZnF_C2H2
|
1295 |
1318 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
1331 |
1354 |
2.49e-1 |
SMART |
|
ZnF_C2H2
|
1360 |
1382 |
1.03e-2 |
SMART |
|
ZnF_C2H2
|
1388 |
1411 |
5.72e-1 |
SMART |
|
ZnF_C2H2
|
1417 |
1440 |
6.75e0 |
SMART |
|
ZnF_C2H2
|
1446 |
1469 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
1488 |
1511 |
1.64e-1 |
SMART |
|
ZnF_C2H2
|
1514 |
1536 |
1.1e-2 |
SMART |
|
ZnF_C2H2
|
1540 |
1563 |
4.05e-1 |
SMART |
|
ZnF_C2H2
|
1580 |
1602 |
4.45e0 |
SMART |
|
ZnF_C2H2
|
1608 |
1630 |
8.81e-2 |
SMART |
|
ZnF_C2H2
|
1636 |
1658 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
1664 |
1686 |
1.2e-3 |
SMART |
|
ZnF_C2H2
|
1692 |
1715 |
3.89e-3 |
SMART |
|
ZnF_C2H2
|
1721 |
1743 |
4.54e-4 |
SMART |
|
ZnF_C2H2
|
1749 |
1771 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
1777 |
1799 |
3.52e-1 |
SMART |
|
low complexity region
|
1829 |
1838 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000027362
|
| SMART Domains |
Protein: ENSMUSP00000027362
Gene: ENSMUSG00000026173
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
17 |
126 |
2.6e-12 |
SMART |
|
EFh
|
138 |
166 |
9.97e-1 |
SMART |
|
EFh
|
174 |
202 |
1.83e1 |
SMART |
|
EFh
|
207 |
234 |
4.45e1 |
SMART |
|
PLCXc
|
290 |
435 |
2.03e-79 |
SMART |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
PLCYc
|
538 |
654 |
1.26e-75 |
SMART |
|
C2
|
673 |
779 |
5.68e-20 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066986
AA Change: V1592A
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000065149
Gene: ENSMUSG00000026135
AA Change: V1592A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
116 |
128 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
162 |
184 |
9.96e-1 |
SMART |
|
ZnF_C2H2
|
190 |
210 |
1.26e1 |
SMART |
|
ZnF_C2H2
|
218 |
241 |
1.47e-3 |
SMART |
|
ZnF_C2H2
|
252 |
274 |
2.75e-3 |
SMART |
|
ZnF_C2H2
|
285 |
310 |
3.34e-2 |
SMART |
|
ZnF_C2H2
|
315 |
339 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
342 |
365 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
371 |
394 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
400 |
422 |
1.56e-2 |
SMART |
|
ZnF_C2H2
|
428 |
450 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
456 |
478 |
1.38e-3 |
SMART |
|
ZnF_C2H2
|
484 |
506 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
511 |
534 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
543 |
566 |
1.31e0 |
SMART |
|
ZnF_C2H2
|
572 |
595 |
2.63e0 |
SMART |
|
low complexity region
|
702 |
718 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
768 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
806 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
838 |
858 |
2.01e1 |
SMART |
|
ZnF_C2H2
|
868 |
888 |
1.91e1 |
SMART |
|
low complexity region
|
946 |
959 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
986 |
1006 |
2.7e2 |
SMART |
|
low complexity region
|
1008 |
1021 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1064 |
1084 |
3.56e1 |
SMART |
|
ZnF_C2H2
|
1094 |
1117 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
1130 |
1153 |
2.49e-1 |
SMART |
|
ZnF_C2H2
|
1159 |
1181 |
1.03e-2 |
SMART |
|
ZnF_C2H2
|
1187 |
1210 |
5.72e-1 |
SMART |
|
ZnF_C2H2
|
1216 |
1239 |
6.75e0 |
SMART |
|
ZnF_C2H2
|
1245 |
1268 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
1287 |
1310 |
1.64e-1 |
SMART |
|
ZnF_C2H2
|
1313 |
1335 |
1.1e-2 |
SMART |
|
ZnF_C2H2
|
1339 |
1362 |
4.05e-1 |
SMART |
|
ZnF_C2H2
|
1379 |
1401 |
4.45e0 |
SMART |
|
ZnF_C2H2
|
1407 |
1429 |
8.81e-2 |
SMART |
|
ZnF_C2H2
|
1435 |
1457 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
1463 |
1485 |
1.2e-3 |
SMART |
|
ZnF_C2H2
|
1491 |
1514 |
3.89e-3 |
SMART |
|
ZnF_C2H2
|
1520 |
1542 |
4.54e-4 |
SMART |
|
ZnF_C2H2
|
1548 |
1570 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
1576 |
1598 |
3.52e-1 |
SMART |
|
low complexity region
|
1628 |
1637 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000067916
|
| SMART Domains |
Protein: ENSMUSP00000064413
Gene: ENSMUSG00000026173
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
17 |
126 |
2.6e-12 |
SMART |
|
EFh
|
138 |
166 |
9.97e-1 |
SMART |
|
EFh
|
174 |
202 |
1.83e1 |
SMART |
|
EFh
|
207 |
234 |
4.45e1 |
SMART |
|
PLCXc
|
290 |
435 |
2.03e-79 |
SMART |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
PLCYc
|
506 |
622 |
1.26e-75 |
SMART |
|
C2
|
641 |
747 |
5.68e-20 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113737
AA Change: V1690A
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000109366
Gene: ENSMUSG00000026135
AA Change: V1690A
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
93 |
115 |
9.81e1 |
SMART |
|
ZnF_C2H2
|
120 |
144 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
147 |
169 |
9.96e-1 |
SMART |
|
low complexity region
|
214 |
226 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
260 |
282 |
9.96e-1 |
SMART |
|
ZnF_C2H2
|
288 |
308 |
1.26e1 |
SMART |
|
ZnF_C2H2
|
316 |
339 |
1.47e-3 |
SMART |
|
ZnF_C2H2
|
350 |
372 |
2.75e-3 |
SMART |
|
ZnF_C2H2
|
383 |
408 |
3.34e-2 |
SMART |
|
ZnF_C2H2
|
413 |
437 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
440 |
463 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
469 |
492 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
498 |
520 |
1.56e-2 |
SMART |
|
ZnF_C2H2
|
526 |
548 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
554 |
576 |
1.38e-3 |
SMART |
|
ZnF_C2H2
|
582 |
604 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
609 |
632 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
641 |
664 |
1.31e0 |
SMART |
|
ZnF_C2H2
|
670 |
693 |
2.63e0 |
SMART |
|
low complexity region
|
800 |
816 |
N/A |
INTRINSIC |
|
low complexity region
|
850 |
866 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
904 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
936 |
956 |
2.01e1 |
SMART |
|
ZnF_C2H2
|
966 |
986 |
1.91e1 |
SMART |
|
low complexity region
|
1044 |
1057 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1084 |
1104 |
2.7e2 |
SMART |
|
low complexity region
|
1106 |
1119 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1162 |
1182 |
3.56e1 |
SMART |
|
ZnF_C2H2
|
1192 |
1215 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
1228 |
1251 |
2.49e-1 |
SMART |
|
ZnF_C2H2
|
1257 |
1279 |
1.03e-2 |
SMART |
|
ZnF_C2H2
|
1285 |
1308 |
5.72e-1 |
SMART |
|
ZnF_C2H2
|
1314 |
1337 |
6.75e0 |
SMART |
|
ZnF_C2H2
|
1343 |
1366 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
1385 |
1408 |
1.64e-1 |
SMART |
|
ZnF_C2H2
|
1411 |
1433 |
1.1e-2 |
SMART |
|
ZnF_C2H2
|
1437 |
1460 |
4.05e-1 |
SMART |
|
ZnF_C2H2
|
1477 |
1499 |
4.45e0 |
SMART |
|
ZnF_C2H2
|
1505 |
1527 |
8.81e-2 |
SMART |
|
ZnF_C2H2
|
1533 |
1555 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
1561 |
1583 |
1.2e-3 |
SMART |
|
ZnF_C2H2
|
1589 |
1612 |
3.89e-3 |
SMART |
|
ZnF_C2H2
|
1618 |
1640 |
4.54e-4 |
SMART |
|
ZnF_C2H2
|
1646 |
1668 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
1674 |
1696 |
3.52e-1 |
SMART |
|
low complexity region
|
1726 |
1735 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113747
|
| SMART Domains |
Protein: ENSMUSP00000109376
Gene: ENSMUSG00000026173
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
17 |
126 |
2.6e-12 |
SMART |
|
EFh
|
138 |
166 |
9.97e-1 |
SMART |
|
EFh
|
174 |
202 |
1.83e1 |
SMART |
|
EFh
|
207 |
234 |
4.45e1 |
SMART |
|
PLCXc
|
290 |
435 |
2.03e-79 |
SMART |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
PLCYc
|
506 |
622 |
1.26e-75 |
SMART |
|
C2
|
641 |
747 |
5.68e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113749
|
| SMART Domains |
Protein: ENSMUSP00000109378
Gene: ENSMUSG00000026173
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
17 |
126 |
2.6e-12 |
SMART |
|
EFh
|
138 |
166 |
9.97e-1 |
SMART |
|
EFh
|
174 |
202 |
1.83e1 |
SMART |
|
EFh
|
207 |
234 |
4.45e1 |
SMART |
|
PLCXc
|
290 |
435 |
2.03e-79 |
SMART |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
PLCYc
|
538 |
654 |
1.26e-75 |
SMART |
|
C2
|
673 |
779 |
5.68e-20 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135111
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000189956
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141412
|
| SMART Domains |
Protein: ENSMUSP00000115322
Gene: ENSMUSG00000026173
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
17 |
126 |
2.6e-12 |
SMART |
|
EFh
|
138 |
166 |
9.97e-1 |
SMART |
|
EFh
|
174 |
202 |
1.83e1 |
SMART |
|
EFh
|
207 |
234 |
4.45e1 |
SMART |
|
PLCXc
|
290 |
435 |
2.03e-79 |
SMART |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000127921
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156613
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113750
|
| SMART Domains |
Protein: ENSMUSP00000109379
Gene: ENSMUSG00000026173
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
17 |
126 |
2.6e-12 |
SMART |
|
EFh
|
138 |
166 |
9.97e-1 |
SMART |
|
EFh
|
174 |
202 |
1.83e1 |
SMART |
|
EFh
|
207 |
234 |
4.45e1 |
SMART |
|
PLCXc
|
290 |
435 |
2.03e-79 |
SMART |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
PLCYc
|
506 |
622 |
1.26e-75 |
SMART |
|
C2
|
641 |
747 |
7.16e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152707
|
| SMART Domains |
Protein: ENSMUSP00000121732
Gene: ENSMUSG00000026173
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
17 |
126 |
2.6e-12 |
SMART |
|
EFh
|
138 |
166 |
9.97e-1 |
SMART |
|
EFh
|
174 |
202 |
1.83e1 |
SMART |
|
EFh
|
207 |
234 |
4.45e1 |
SMART |
|
PLCXc
|
290 |
435 |
2.03e-79 |
SMART |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 52 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acvr1b |
G |
A |
15: 101,100,975 (GRCm39) |
R379Q |
probably null |
Het |
| Adam23 |
C |
T |
1: 63,574,335 (GRCm39) |
Q276* |
probably null |
Het |
| Apob |
A |
T |
12: 8,057,499 (GRCm39) |
S1961C |
probably damaging |
Het |
| Atxn7l1 |
C |
T |
12: 33,408,839 (GRCm39) |
P334S |
probably damaging |
Het |
| Ccnb1 |
T |
C |
13: 100,917,827 (GRCm39) |
M258V |
possibly damaging |
Het |
| Cd34 |
A |
C |
1: 194,630,260 (GRCm39) |
T65P |
possibly damaging |
Het |
| Cog6 |
A |
G |
3: 52,907,900 (GRCm39) |
|
probably null |
Het |
| Cp |
T |
C |
3: 20,041,734 (GRCm39) |
M953T |
probably damaging |
Het |
| Cwc27 |
C |
T |
13: 104,768,130 (GRCm39) |
R455Q |
unknown |
Het |
| Dhx57 |
A |
T |
17: 80,588,663 (GRCm39) |
D63E |
probably damaging |
Het |
| Elapor1 |
A |
T |
3: 108,378,726 (GRCm39) |
Y409* |
probably null |
Het |
| Flt4 |
T |
A |
11: 49,536,786 (GRCm39) |
M1252K |
possibly damaging |
Het |
| Gfral |
C |
T |
9: 76,100,631 (GRCm39) |
C269Y |
probably damaging |
Het |
| Itih4 |
C |
T |
14: 30,621,351 (GRCm39) |
Q788* |
probably null |
Het |
| Kif18b |
A |
G |
11: 102,803,214 (GRCm39) |
S499P |
probably benign |
Het |
| Map1a |
G |
C |
2: 121,130,768 (GRCm39) |
R528P |
probably damaging |
Het |
| Map3k5 |
T |
C |
10: 20,003,443 (GRCm39) |
F1152L |
probably damaging |
Het |
| Marveld2 |
T |
C |
13: 100,748,599 (GRCm39) |
D160G |
probably benign |
Het |
| Mtcl2 |
A |
T |
2: 156,882,013 (GRCm39) |
C680S |
probably benign |
Het |
| Mug1 |
A |
T |
6: 121,847,469 (GRCm39) |
M616L |
probably benign |
Het |
| Ndst4 |
A |
T |
3: 125,231,823 (GRCm39) |
I131F |
probably benign |
Het |
| Neto1 |
G |
T |
18: 86,479,399 (GRCm39) |
A196S |
probably benign |
Het |
| Notum |
A |
G |
11: 120,545,237 (GRCm39) |
F441L |
probably benign |
Het |
| Nsmce4a |
A |
G |
7: 130,140,769 (GRCm39) |
I239T |
probably benign |
Het |
| Or51g1 |
A |
T |
7: 102,633,647 (GRCm39) |
N241K |
possibly damaging |
Het |
| Or52z14 |
T |
A |
7: 103,252,943 (GRCm39) |
D27E |
probably benign |
Het |
| Or5d35 |
A |
T |
2: 87,855,707 (GRCm39) |
I214F |
probably damaging |
Het |
| Or6s1 |
T |
A |
14: 51,307,870 (GRCm39) |
K327* |
probably null |
Het |
| Or6x1 |
A |
T |
9: 40,098,980 (GRCm39) |
T190S |
possibly damaging |
Het |
| Or8k40 |
A |
G |
2: 86,584,398 (GRCm39) |
M228T |
probably damaging |
Het |
| Pde4dip |
A |
T |
3: 97,700,841 (GRCm39) |
V221D |
probably damaging |
Het |
| Pkp1 |
T |
C |
1: 135,808,545 (GRCm39) |
Y474C |
probably damaging |
Het |
| Ptk6 |
A |
C |
2: 180,838,173 (GRCm39) |
H363Q |
probably benign |
Het |
| Rb1cc1 |
T |
C |
1: 6,342,948 (GRCm39) |
W187R |
probably damaging |
Het |
| Rbfox3 |
A |
T |
11: 118,394,564 (GRCm39) |
F132L |
probably damaging |
Het |
| Rcl1 |
A |
T |
19: 29,099,268 (GRCm39) |
I188F |
possibly damaging |
Het |
| Scfd1 |
T |
A |
12: 51,462,299 (GRCm39) |
S385T |
possibly damaging |
Het |
| Sema6d |
A |
G |
2: 124,501,508 (GRCm39) |
E483G |
possibly damaging |
Het |
| Semp2l2b |
T |
C |
10: 21,943,015 (GRCm39) |
I322V |
possibly damaging |
Het |
| Sipa1l1 |
T |
C |
12: 82,388,890 (GRCm39) |
V372A |
probably benign |
Het |
| Slc17a6 |
G |
A |
7: 51,317,654 (GRCm39) |
G429D |
probably damaging |
Het |
| Slc22a5 |
A |
G |
11: 53,774,532 (GRCm39) |
V151A |
possibly damaging |
Het |
| Spidr |
T |
C |
16: 15,936,787 (GRCm39) |
D106G |
probably damaging |
Het |
| Tekt3 |
A |
T |
11: 62,974,778 (GRCm39) |
T366S |
probably benign |
Het |
| Trpm3 |
T |
C |
19: 22,710,398 (GRCm39) |
M281T |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,782,485 (GRCm39) |
V917A |
probably damaging |
Het |
| Tubgcp4 |
A |
T |
2: 121,014,110 (GRCm39) |
D221V |
possibly damaging |
Het |
| Ubr4 |
C |
T |
4: 139,176,232 (GRCm39) |
R3153W |
probably damaging |
Het |
| Vmn1r89 |
A |
C |
7: 12,954,187 (GRCm39) |
T308P |
possibly damaging |
Het |
| Vmn2r59 |
A |
G |
7: 41,708,326 (GRCm39) |
I27T |
probably benign |
Het |
| Vps13c |
T |
G |
9: 67,895,335 (GRCm39) |
|
probably null |
Het |
| Zfp472 |
T |
A |
17: 33,197,109 (GRCm39) |
C395S |
possibly damaging |
Het |
|
| Other mutations in Zfp142 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00581:Zfp142
|
APN |
1 |
74,606,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00711:Zfp142
|
APN |
1 |
74,611,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01391:Zfp142
|
APN |
1 |
74,618,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01808:Zfp142
|
APN |
1 |
74,615,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02074:Zfp142
|
APN |
1 |
74,609,022 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02134:Zfp142
|
APN |
1 |
74,609,022 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02567:Zfp142
|
APN |
1 |
74,617,309 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02567:Zfp142
|
APN |
1 |
74,617,306 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02567:Zfp142
|
APN |
1 |
74,617,308 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02669:Zfp142
|
APN |
1 |
74,610,432 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL02694:Zfp142
|
APN |
1 |
74,609,307 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02884:Zfp142
|
APN |
1 |
74,611,142 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03000:Zfp142
|
APN |
1 |
74,612,777 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03080:Zfp142
|
APN |
1 |
74,610,368 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL03238:Zfp142
|
APN |
1 |
74,615,437 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03277:Zfp142
|
APN |
1 |
74,610,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4402001:Zfp142
|
UTSW |
1 |
74,618,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0124:Zfp142
|
UTSW |
1 |
74,607,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0256:Zfp142
|
UTSW |
1 |
74,617,317 (GRCm39) |
missense |
probably benign |
|
|
R0267:Zfp142
|
UTSW |
1 |
74,615,223 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0306:Zfp142
|
UTSW |
1 |
74,609,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0321:Zfp142
|
UTSW |
1 |
74,608,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0466:Zfp142
|
UTSW |
1 |
74,624,570 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0513:Zfp142
|
UTSW |
1 |
74,610,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1084:Zfp142
|
UTSW |
1 |
74,610,985 (GRCm39) |
missense |
probably benign |
|
|
R1534:Zfp142
|
UTSW |
1 |
74,611,247 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1548:Zfp142
|
UTSW |
1 |
74,609,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1623:Zfp142
|
UTSW |
1 |
74,610,934 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1628:Zfp142
|
UTSW |
1 |
74,611,047 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1710:Zfp142
|
UTSW |
1 |
74,611,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1722:Zfp142
|
UTSW |
1 |
74,608,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1770:Zfp142
|
UTSW |
1 |
74,618,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2042:Zfp142
|
UTSW |
1 |
74,609,778 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2112:Zfp142
|
UTSW |
1 |
74,612,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4393:Zfp142
|
UTSW |
1 |
74,611,219 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4700:Zfp142
|
UTSW |
1 |
74,609,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4750:Zfp142
|
UTSW |
1 |
74,611,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4763:Zfp142
|
UTSW |
1 |
74,615,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5208:Zfp142
|
UTSW |
1 |
74,610,027 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5233:Zfp142
|
UTSW |
1 |
74,624,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5585:Zfp142
|
UTSW |
1 |
74,617,404 (GRCm39) |
nonsense |
probably null |
|
|
R6192:Zfp142
|
UTSW |
1 |
74,609,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6461:Zfp142
|
UTSW |
1 |
74,606,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6482:Zfp142
|
UTSW |
1 |
74,609,376 (GRCm39) |
splice site |
probably null |
|
|
R7320:Zfp142
|
UTSW |
1 |
74,609,167 (GRCm39) |
nonsense |
probably null |
|
|
R7438:Zfp142
|
UTSW |
1 |
74,624,679 (GRCm39) |
missense |
probably benign |
|
|
R7528:Zfp142
|
UTSW |
1 |
74,610,061 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7600:Zfp142
|
UTSW |
1 |
74,612,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8007:Zfp142
|
UTSW |
1 |
74,610,655 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8681:Zfp142
|
UTSW |
1 |
74,610,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8772:Zfp142
|
UTSW |
1 |
74,610,825 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9058:Zfp142
|
UTSW |
1 |
74,608,955 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Zfp142
|
UTSW |
1 |
74,610,288 (GRCm39) |
missense |
probably benign |
|
|
R9281:Zfp142
|
UTSW |
1 |
74,607,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9302:Zfp142
|
UTSW |
1 |
74,606,302 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9454:Zfp142
|
UTSW |
1 |
74,609,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9569:Zfp142
|
UTSW |
1 |
74,615,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9595:Zfp142
|
UTSW |
1 |
74,611,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9680:Zfp142
|
UTSW |
1 |
74,610,933 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1177:Zfp142
|
UTSW |
1 |
74,609,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCTCAGGCTAGCTATAGTTCC -3'
(R):5'- TCAAGACACGCTTCCTGCTG -3'
Sequencing Primer
(F):5'- CAGGCTAGCTATAGTTCCAATTTGC -3'
(R):5'- GCTTCCTGCTGCGCACC -3'
|
| Posted On |
2014-10-15 |
Incidental Mutation