Incidental Mutation 'R2219:Ccdc180'
| ID |
241318 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc180
|
| Ensembl Gene |
ENSMUSG00000035539 |
| Gene Name |
coiled-coil domain containing 180 |
| Synonyms |
LOC381522, E230008N13Rik |
| MMRRC Submission |
040221-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2219 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
45890303-45950774 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 45944949 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1452
(N1452K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136714
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000178561]
|
| AlphaFold |
J3QNE4 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000149903
AA Change: N1276K
|
| SMART Domains |
Protein: ENSMUSP00000119784
Gene: ENSMUSG00000035539
AA Change: N1276K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
42 |
N/A |
INTRINSIC |
|
coiled coil region
|
90 |
117 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
141 |
609 |
2e-189 |
PFAM |
|
low complexity region
|
628 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
658 |
675 |
N/A |
INTRINSIC |
|
coiled coil region
|
710 |
780 |
N/A |
INTRINSIC |
|
coiled coil region
|
945 |
979 |
N/A |
INTRINSIC |
|
low complexity region
|
1100 |
1123 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1169 |
1372 |
9.5e-77 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000178561
AA Change: N1452K
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000136714
Gene: ENSMUSG00000035539
AA Change: N1452K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
49 |
N/A |
INTRINSIC |
|
coiled coil region
|
98 |
125 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
148 |
616 |
7.3e-189 |
PFAM |
|
low complexity region
|
635 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
682 |
N/A |
INTRINSIC |
|
coiled coil region
|
718 |
788 |
N/A |
INTRINSIC |
|
coiled coil region
|
1121 |
1155 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1298 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1344 |
1547 |
2.2e-76 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a coiled-coil domain. Alternative splicing results in multiple transcript variants encoding different isoforms. A single nucleotide polymorphism (SNP) in this gene has been associated with increased susceptibility to Behcet's Disease (PMID: 19442274). [provided by RefSeq, Dec 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933421I07Rik |
A |
G |
7: 42,095,769 (GRCm39) |
Y160H |
probably damaging |
Het |
| Adamts16 |
G |
A |
13: 70,927,637 (GRCm39) |
|
probably benign |
Het |
| Adgre1 |
T |
A |
17: 57,708,912 (GRCm39) |
N34K |
possibly damaging |
Het |
| Ago2 |
T |
A |
15: 73,018,260 (GRCm39) |
E59D |
probably benign |
Het |
| Akap8l |
G |
T |
17: 32,553,605 (GRCm39) |
Q372K |
probably benign |
Het |
| Aox1 |
A |
G |
1: 58,388,289 (GRCm39) |
|
probably null |
Het |
| Apc2 |
T |
C |
10: 80,144,943 (GRCm39) |
V618A |
probably benign |
Het |
| Cacna1d |
A |
T |
14: 29,764,047 (GRCm39) |
C2140S |
probably damaging |
Het |
| Cadps2 |
A |
G |
6: 23,410,831 (GRCm39) |
L671P |
probably damaging |
Het |
| Capn9 |
C |
T |
8: 125,335,898 (GRCm39) |
R529* |
probably null |
Het |
| Cdh5 |
A |
T |
8: 104,869,538 (GRCm39) |
I755F |
possibly damaging |
Het |
| Cdkal1 |
T |
A |
13: 29,538,741 (GRCm39) |
M473L |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,943,184 (GRCm39) |
I1614V |
probably damaging |
Het |
| Champ1 |
A |
G |
8: 13,930,017 (GRCm39) |
H725R |
probably damaging |
Het |
| Cntnap5a |
A |
T |
1: 116,508,369 (GRCm39) |
T1294S |
possibly damaging |
Het |
| Cops8 |
A |
C |
1: 90,534,341 (GRCm39) |
N94T |
probably benign |
Het |
| Cpne7 |
G |
T |
8: 123,851,177 (GRCm39) |
V155L |
probably benign |
Het |
| Dhx29 |
T |
C |
13: 113,089,338 (GRCm39) |
V703A |
probably damaging |
Het |
| Dhx30 |
A |
G |
9: 109,916,703 (GRCm39) |
L575P |
probably damaging |
Het |
| Dmc1 |
T |
A |
15: 79,469,327 (GRCm39) |
H156L |
possibly damaging |
Het |
| Dnmt3a |
A |
G |
12: 3,899,654 (GRCm39) |
|
probably benign |
Het |
| Dst |
C |
G |
1: 34,209,514 (GRCm39) |
L869V |
probably damaging |
Het |
| Eif3d |
A |
T |
15: 77,849,142 (GRCm39) |
M180K |
probably benign |
Het |
| Erbb3 |
T |
C |
10: 128,405,740 (GRCm39) |
T1173A |
probably damaging |
Het |
| Fat4 |
A |
T |
3: 39,064,364 (GRCm39) |
K4773N |
probably damaging |
Het |
| Fbn2 |
G |
A |
18: 58,186,035 (GRCm39) |
P1771L |
possibly damaging |
Het |
| Fer1l4 |
T |
G |
2: 155,873,684 (GRCm39) |
Y1207S |
probably damaging |
Het |
| Fermt2 |
G |
A |
14: 45,713,354 (GRCm39) |
T87I |
probably benign |
Het |
| Fpr3 |
T |
A |
17: 18,191,644 (GRCm39) |
M305K |
possibly damaging |
Het |
| Fzd2 |
A |
G |
11: 102,496,249 (GRCm39) |
E231G |
probably benign |
Het |
| Ggcx |
T |
C |
6: 72,404,965 (GRCm39) |
Y458H |
probably benign |
Het |
| Ggt7 |
A |
G |
2: 155,337,639 (GRCm39) |
S504P |
probably damaging |
Het |
| Gm4884 |
A |
G |
7: 40,692,910 (GRCm39) |
H293R |
possibly damaging |
Het |
| Gm5475 |
A |
G |
15: 100,322,094 (GRCm39) |
|
probably benign |
Het |
| Gm5930 |
A |
T |
14: 44,573,993 (GRCm39) |
L115M |
probably damaging |
Het |
| Itln1 |
T |
A |
1: 171,359,115 (GRCm39) |
T122S |
probably damaging |
Het |
| Itpr3 |
T |
A |
17: 27,334,027 (GRCm39) |
L2033Q |
probably benign |
Het |
| Lama2 |
T |
C |
10: 26,919,565 (GRCm39) |
D2222G |
probably damaging |
Het |
| Lars2 |
T |
C |
9: 123,247,845 (GRCm39) |
L334P |
probably damaging |
Het |
| Ly9 |
T |
C |
1: 171,425,249 (GRCm39) |
|
probably null |
Het |
| Man1a |
T |
C |
10: 53,853,145 (GRCm39) |
I324M |
probably damaging |
Het |
| Mast3 |
T |
C |
8: 71,233,607 (GRCm39) |
E994G |
probably damaging |
Het |
| Mettl21a |
A |
T |
1: 64,655,442 (GRCm39) |
V46E |
probably damaging |
Het |
| Mmp15 |
A |
G |
8: 96,096,801 (GRCm39) |
D398G |
probably benign |
Het |
| Mybpc1 |
T |
A |
10: 88,391,540 (GRCm39) |
D319V |
probably damaging |
Het |
| Or10ad1c |
T |
A |
15: 98,084,848 (GRCm39) |
K277* |
probably null |
Het |
| Or4a47 |
A |
T |
2: 89,665,769 (GRCm39) |
D173E |
probably damaging |
Het |
| Or4a78 |
A |
T |
2: 89,498,211 (GRCm39) |
N6K |
possibly damaging |
Het |
| Or4c35 |
G |
A |
2: 89,808,256 (GRCm39) |
V45I |
possibly damaging |
Het |
| Or4f61 |
A |
T |
2: 111,922,752 (GRCm39) |
I98N |
probably damaging |
Het |
| Or5b113 |
T |
A |
19: 13,342,901 (GRCm39) |
I303N |
possibly damaging |
Het |
| Or5p5 |
G |
A |
7: 107,414,429 (GRCm39) |
V213I |
probably benign |
Het |
| Or9m1 |
A |
C |
2: 87,733,269 (GRCm39) |
Y250* |
probably null |
Het |
| Otogl |
C |
T |
10: 107,692,838 (GRCm39) |
C882Y |
probably damaging |
Het |
| Parp10 |
A |
G |
15: 76,117,783 (GRCm39) |
Y868H |
probably damaging |
Het |
| Pick1 |
T |
A |
15: 79,123,899 (GRCm39) |
I90N |
probably damaging |
Het |
| Piezo1 |
C |
T |
8: 123,218,227 (GRCm39) |
V1170I |
probably benign |
Het |
| Pim3 |
G |
A |
15: 88,747,115 (GRCm39) |
V54I |
possibly damaging |
Het |
| Pinlyp |
T |
C |
7: 24,245,433 (GRCm39) |
|
probably benign |
Het |
| Pira12 |
A |
T |
7: 3,900,488 (GRCm39) |
N87K |
probably benign |
Het |
| Ppfia3 |
G |
A |
7: 45,004,314 (GRCm39) |
Q473* |
probably null |
Het |
| Rab3gap2 |
G |
A |
1: 185,008,113 (GRCm39) |
G1056E |
probably damaging |
Het |
| Ralgapa2 |
G |
A |
2: 146,263,599 (GRCm39) |
T706I |
probably benign |
Het |
| Reln |
T |
C |
5: 22,177,045 (GRCm39) |
T1874A |
possibly damaging |
Het |
| Rftn1 |
C |
A |
17: 50,476,173 (GRCm39) |
M1I |
probably null |
Het |
| Ros1 |
T |
A |
10: 52,042,175 (GRCm39) |
Q250L |
probably damaging |
Het |
| Slc11a1 |
T |
A |
1: 74,419,824 (GRCm39) |
F166I |
probably damaging |
Het |
| Slc17a9 |
A |
G |
2: 180,373,755 (GRCm39) |
T59A |
probably benign |
Het |
| Slc26a5 |
T |
C |
5: 22,028,476 (GRCm39) |
K364R |
probably damaging |
Het |
| Slitrk2 |
T |
C |
X: 65,698,754 (GRCm39) |
I415T |
probably damaging |
Het |
| Stom |
A |
G |
2: 35,211,613 (GRCm39) |
I136T |
possibly damaging |
Het |
| Strc |
G |
T |
2: 121,195,004 (GRCm39) |
P1728T |
probably damaging |
Het |
| Telo2 |
C |
A |
17: 25,322,673 (GRCm39) |
V640F |
probably benign |
Het |
| Tg |
T |
C |
15: 66,553,782 (GRCm39) |
V399A |
probably benign |
Het |
| Tmem214 |
A |
G |
5: 31,030,975 (GRCm39) |
K383E |
possibly damaging |
Het |
| Tomm40l |
A |
T |
1: 171,049,550 (GRCm39) |
L13* |
probably null |
Het |
| Tonsl |
A |
T |
15: 76,518,840 (GRCm39) |
N526K |
probably damaging |
Het |
| Top2b |
T |
G |
14: 16,409,189 (GRCm38) |
I777M |
probably damaging |
Het |
| Tymp |
T |
A |
15: 89,258,965 (GRCm39) |
M240L |
probably benign |
Het |
| Ubr2 |
A |
T |
17: 47,296,968 (GRCm39) |
S271T |
possibly damaging |
Het |
| Uggt2 |
A |
T |
14: 119,312,749 (GRCm39) |
N353K |
probably damaging |
Het |
| Ugt2b35 |
T |
A |
5: 87,151,191 (GRCm39) |
F266I |
possibly damaging |
Het |
| Vmn2r103 |
C |
T |
17: 20,013,909 (GRCm39) |
R234W |
probably damaging |
Het |
| Zfp109 |
C |
A |
7: 23,927,886 (GRCm39) |
D508Y |
probably damaging |
Het |
| Zfp623 |
T |
C |
15: 75,819,379 (GRCm39) |
S112P |
possibly damaging |
Het |
| Zfp735 |
A |
G |
11: 73,601,851 (GRCm39) |
N265S |
possibly damaging |
Het |
| Zfp879 |
A |
G |
11: 50,724,094 (GRCm39) |
C321R |
probably damaging |
Het |
|
| Other mutations in Ccdc180 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01369:Ccdc180
|
APN |
4 |
45,900,256 (GRCm39) |
missense |
probably benign |
|
|
IGL01713:Ccdc180
|
APN |
4 |
45,921,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01915:Ccdc180
|
APN |
4 |
45,904,544 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01935:Ccdc180
|
APN |
4 |
45,906,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02539:Ccdc180
|
APN |
4 |
45,921,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02982:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03071:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03146:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
PIT4687001:Ccdc180
|
UTSW |
4 |
45,949,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0080:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0082:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0126:Ccdc180
|
UTSW |
4 |
45,912,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0193:Ccdc180
|
UTSW |
4 |
45,914,803 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0276:Ccdc180
|
UTSW |
4 |
45,923,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Ccdc180
|
UTSW |
4 |
45,923,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Ccdc180
|
UTSW |
4 |
45,930,197 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0468:Ccdc180
|
UTSW |
4 |
45,923,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0539:Ccdc180
|
UTSW |
4 |
45,922,010 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0543:Ccdc180
|
UTSW |
4 |
45,900,041 (GRCm39) |
nonsense |
probably null |
|
|
R0546:Ccdc180
|
UTSW |
4 |
45,904,597 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0612:Ccdc180
|
UTSW |
4 |
45,927,969 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0792:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1056:Ccdc180
|
UTSW |
4 |
45,916,375 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1099:Ccdc180
|
UTSW |
4 |
45,914,225 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1136:Ccdc180
|
UTSW |
4 |
45,914,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1263:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1331:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1522:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1819:Ccdc180
|
UTSW |
4 |
45,926,195 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2022:Ccdc180
|
UTSW |
4 |
45,944,418 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2056:Ccdc180
|
UTSW |
4 |
45,932,477 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2228:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2229:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2255:Ccdc180
|
UTSW |
4 |
45,921,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2427:Ccdc180
|
UTSW |
4 |
45,929,545 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3001:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3002:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3003:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3110:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3111:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3112:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3898:Ccdc180
|
UTSW |
4 |
45,912,799 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4022:Ccdc180
|
UTSW |
4 |
45,904,560 (GRCm39) |
nonsense |
probably null |
|
|
R4084:Ccdc180
|
UTSW |
4 |
45,950,632 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4377:Ccdc180
|
UTSW |
4 |
45,941,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4595:Ccdc180
|
UTSW |
4 |
45,945,023 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4637:Ccdc180
|
UTSW |
4 |
45,914,443 (GRCm39) |
missense |
probably benign |
|
|
R4811:Ccdc180
|
UTSW |
4 |
45,928,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Ccdc180
|
UTSW |
4 |
45,912,794 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4858:Ccdc180
|
UTSW |
4 |
45,923,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4888:Ccdc180
|
UTSW |
4 |
45,909,308 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,453 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5042:Ccdc180
|
UTSW |
4 |
45,916,255 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5119:Ccdc180
|
UTSW |
4 |
45,914,603 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5177:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5311:Ccdc180
|
UTSW |
4 |
45,917,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5333:Ccdc180
|
UTSW |
4 |
45,890,935 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5448:Ccdc180
|
UTSW |
4 |
45,920,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5510:Ccdc180
|
UTSW |
4 |
45,928,046 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6018:Ccdc180
|
UTSW |
4 |
45,926,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6108:Ccdc180
|
UTSW |
4 |
45,911,389 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6283:Ccdc180
|
UTSW |
4 |
45,902,486 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6483:Ccdc180
|
UTSW |
4 |
45,921,950 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6618:Ccdc180
|
UTSW |
4 |
45,950,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7017:Ccdc180
|
UTSW |
4 |
45,940,934 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7205:Ccdc180
|
UTSW |
4 |
45,914,588 (GRCm39) |
missense |
probably benign |
|
|
R7341:Ccdc180
|
UTSW |
4 |
45,898,644 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7351:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7418:Ccdc180
|
UTSW |
4 |
45,904,616 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7492:Ccdc180
|
UTSW |
4 |
45,930,009 (GRCm39) |
splice site |
probably null |
|
|
R7573:Ccdc180
|
UTSW |
4 |
45,922,015 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7639:Ccdc180
|
UTSW |
4 |
45,928,043 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7792:Ccdc180
|
UTSW |
4 |
45,890,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7806:Ccdc180
|
UTSW |
4 |
45,912,801 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7812:Ccdc180
|
UTSW |
4 |
45,906,952 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7840:Ccdc180
|
UTSW |
4 |
45,900,461 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7842:Ccdc180
|
UTSW |
4 |
45,909,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8712:Ccdc180
|
UTSW |
4 |
45,920,842 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8818:Ccdc180
|
UTSW |
4 |
45,900,484 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8961:Ccdc180
|
UTSW |
4 |
45,929,573 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R8983:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9035:Ccdc180
|
UTSW |
4 |
45,906,922 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Ccdc180
|
UTSW |
4 |
45,949,466 (GRCm39) |
nonsense |
probably null |
|
|
R9240:Ccdc180
|
UTSW |
4 |
45,917,566 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9293:Ccdc180
|
UTSW |
4 |
45,944,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Ccdc180
|
UTSW |
4 |
45,902,447 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9346:Ccdc180
|
UTSW |
4 |
45,927,953 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9521:Ccdc180
|
UTSW |
4 |
45,916,283 (GRCm39) |
missense |
probably null |
0.50 |
|
R9653:Ccdc180
|
UTSW |
4 |
45,923,495 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9667:Ccdc180
|
UTSW |
4 |
45,920,861 (GRCm39) |
nonsense |
probably null |
|
|
X0017:Ccdc180
|
UTSW |
4 |
45,909,350 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,920,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,916,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAAAGGTCCAGATGGTGCTG -3'
(R):5'- ATCAGGCCTAGCTCTCTGAAGG -3'
Sequencing Primer
(F):5'- TGGAGCAGGTACTCAGCTC -3'
(R):5'- TCTCTGAAGGGCGGCATG -3'
|
| Posted On |
2014-10-15 |
Incidental Mutation