Incidental Mutation 'R2219:Adamts16'
| ID |
241357 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts16
|
| Ensembl Gene |
ENSMUSG00000049538 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 16 |
| Synonyms |
|
| MMRRC Submission |
040221-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2219 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
70875921-70989930 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site |
| DNA Base Change (assembly) |
G to A
at 70927637 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000122031
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080145]
[ENSMUST00000109694]
[ENSMUST00000123552]
|
| AlphaFold |
Q69Z28 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080145
|
| SMART Domains |
Protein: ENSMUSP00000079041
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
57 |
203 |
7.8e-34 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
2.9e-13 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
1.2e-8 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
5.4e-32 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
3.7e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
6.4e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
Pfam:ADAM_spacer1
|
744 |
856 |
1.3e-37 |
PFAM |
|
TSP1
|
872 |
926 |
3.48e0 |
SMART |
|
TSP1
|
928 |
985 |
4.84e-3 |
SMART |
|
TSP1
|
987 |
1046 |
1.49e-3 |
SMART |
|
TSP1
|
1052 |
1113 |
3.19e-2 |
SMART |
|
TSP1
|
1127 |
1179 |
7.68e-6 |
SMART |
|
Pfam:PLAC
|
1188 |
1218 |
2.9e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109694
|
| SMART Domains |
Protein: ENSMUSP00000105316
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
56 |
203 |
2.2e-32 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
1.8e-13 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
7.3e-9 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
4.6e-33 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
4.1e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
3.3e-10 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
Pfam:ADAM_spacer1
|
744 |
856 |
1.3e-37 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123552
|
| SMART Domains |
Protein: ENSMUSP00000122031
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
56 |
203 |
5.9e-33 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
5.1e-14 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
2.2e-9 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
1.2e-33 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
1.2e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
9.7e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
| Meta Mutation Damage Score |
0.0967 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933421I07Rik |
A |
G |
7: 42,095,769 (GRCm39) |
Y160H |
probably damaging |
Het |
| Adgre1 |
T |
A |
17: 57,708,912 (GRCm39) |
N34K |
possibly damaging |
Het |
| Ago2 |
T |
A |
15: 73,018,260 (GRCm39) |
E59D |
probably benign |
Het |
| Akap8l |
G |
T |
17: 32,553,605 (GRCm39) |
Q372K |
probably benign |
Het |
| Aox1 |
A |
G |
1: 58,388,289 (GRCm39) |
|
probably null |
Het |
| Apc2 |
T |
C |
10: 80,144,943 (GRCm39) |
V618A |
probably benign |
Het |
| Cacna1d |
A |
T |
14: 29,764,047 (GRCm39) |
C2140S |
probably damaging |
Het |
| Cadps2 |
A |
G |
6: 23,410,831 (GRCm39) |
L671P |
probably damaging |
Het |
| Capn9 |
C |
T |
8: 125,335,898 (GRCm39) |
R529* |
probably null |
Het |
| Ccdc180 |
T |
A |
4: 45,944,949 (GRCm39) |
N1452K |
probably damaging |
Het |
| Cdh5 |
A |
T |
8: 104,869,538 (GRCm39) |
I755F |
possibly damaging |
Het |
| Cdkal1 |
T |
A |
13: 29,538,741 (GRCm39) |
M473L |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,943,184 (GRCm39) |
I1614V |
probably damaging |
Het |
| Champ1 |
A |
G |
8: 13,930,017 (GRCm39) |
H725R |
probably damaging |
Het |
| Cntnap5a |
A |
T |
1: 116,508,369 (GRCm39) |
T1294S |
possibly damaging |
Het |
| Cops8 |
A |
C |
1: 90,534,341 (GRCm39) |
N94T |
probably benign |
Het |
| Cpne7 |
G |
T |
8: 123,851,177 (GRCm39) |
V155L |
probably benign |
Het |
| Dhx29 |
T |
C |
13: 113,089,338 (GRCm39) |
V703A |
probably damaging |
Het |
| Dhx30 |
A |
G |
9: 109,916,703 (GRCm39) |
L575P |
probably damaging |
Het |
| Dmc1 |
T |
A |
15: 79,469,327 (GRCm39) |
H156L |
possibly damaging |
Het |
| Dnmt3a |
A |
G |
12: 3,899,654 (GRCm39) |
|
probably benign |
Het |
| Dst |
C |
G |
1: 34,209,514 (GRCm39) |
L869V |
probably damaging |
Het |
| Eif3d |
A |
T |
15: 77,849,142 (GRCm39) |
M180K |
probably benign |
Het |
| Erbb3 |
T |
C |
10: 128,405,740 (GRCm39) |
T1173A |
probably damaging |
Het |
| Fat4 |
A |
T |
3: 39,064,364 (GRCm39) |
K4773N |
probably damaging |
Het |
| Fbn2 |
G |
A |
18: 58,186,035 (GRCm39) |
P1771L |
possibly damaging |
Het |
| Fer1l4 |
T |
G |
2: 155,873,684 (GRCm39) |
Y1207S |
probably damaging |
Het |
| Fermt2 |
G |
A |
14: 45,713,354 (GRCm39) |
T87I |
probably benign |
Het |
| Fpr3 |
T |
A |
17: 18,191,644 (GRCm39) |
M305K |
possibly damaging |
Het |
| Fzd2 |
A |
G |
11: 102,496,249 (GRCm39) |
E231G |
probably benign |
Het |
| Ggcx |
T |
C |
6: 72,404,965 (GRCm39) |
Y458H |
probably benign |
Het |
| Ggt7 |
A |
G |
2: 155,337,639 (GRCm39) |
S504P |
probably damaging |
Het |
| Gm4884 |
A |
G |
7: 40,692,910 (GRCm39) |
H293R |
possibly damaging |
Het |
| Gm5475 |
A |
G |
15: 100,322,094 (GRCm39) |
|
probably benign |
Het |
| Gm5930 |
A |
T |
14: 44,573,993 (GRCm39) |
L115M |
probably damaging |
Het |
| Itln1 |
T |
A |
1: 171,359,115 (GRCm39) |
T122S |
probably damaging |
Het |
| Itpr3 |
T |
A |
17: 27,334,027 (GRCm39) |
L2033Q |
probably benign |
Het |
| Lama2 |
T |
C |
10: 26,919,565 (GRCm39) |
D2222G |
probably damaging |
Het |
| Lars2 |
T |
C |
9: 123,247,845 (GRCm39) |
L334P |
probably damaging |
Het |
| Ly9 |
T |
C |
1: 171,425,249 (GRCm39) |
|
probably null |
Het |
| Man1a |
T |
C |
10: 53,853,145 (GRCm39) |
I324M |
probably damaging |
Het |
| Mast3 |
T |
C |
8: 71,233,607 (GRCm39) |
E994G |
probably damaging |
Het |
| Mettl21a |
A |
T |
1: 64,655,442 (GRCm39) |
V46E |
probably damaging |
Het |
| Mmp15 |
A |
G |
8: 96,096,801 (GRCm39) |
D398G |
probably benign |
Het |
| Mybpc1 |
T |
A |
10: 88,391,540 (GRCm39) |
D319V |
probably damaging |
Het |
| Or10ad1c |
T |
A |
15: 98,084,848 (GRCm39) |
K277* |
probably null |
Het |
| Or4a47 |
A |
T |
2: 89,665,769 (GRCm39) |
D173E |
probably damaging |
Het |
| Or4a78 |
A |
T |
2: 89,498,211 (GRCm39) |
N6K |
possibly damaging |
Het |
| Or4c35 |
G |
A |
2: 89,808,256 (GRCm39) |
V45I |
possibly damaging |
Het |
| Or4f61 |
A |
T |
2: 111,922,752 (GRCm39) |
I98N |
probably damaging |
Het |
| Or5b113 |
T |
A |
19: 13,342,901 (GRCm39) |
I303N |
possibly damaging |
Het |
| Or5p5 |
G |
A |
7: 107,414,429 (GRCm39) |
V213I |
probably benign |
Het |
| Or9m1 |
A |
C |
2: 87,733,269 (GRCm39) |
Y250* |
probably null |
Het |
| Otogl |
C |
T |
10: 107,692,838 (GRCm39) |
C882Y |
probably damaging |
Het |
| Parp10 |
A |
G |
15: 76,117,783 (GRCm39) |
Y868H |
probably damaging |
Het |
| Pick1 |
T |
A |
15: 79,123,899 (GRCm39) |
I90N |
probably damaging |
Het |
| Piezo1 |
C |
T |
8: 123,218,227 (GRCm39) |
V1170I |
probably benign |
Het |
| Pim3 |
G |
A |
15: 88,747,115 (GRCm39) |
V54I |
possibly damaging |
Het |
| Pinlyp |
T |
C |
7: 24,245,433 (GRCm39) |
|
probably benign |
Het |
| Pira12 |
A |
T |
7: 3,900,488 (GRCm39) |
N87K |
probably benign |
Het |
| Ppfia3 |
G |
A |
7: 45,004,314 (GRCm39) |
Q473* |
probably null |
Het |
| Rab3gap2 |
G |
A |
1: 185,008,113 (GRCm39) |
G1056E |
probably damaging |
Het |
| Ralgapa2 |
G |
A |
2: 146,263,599 (GRCm39) |
T706I |
probably benign |
Het |
| Reln |
T |
C |
5: 22,177,045 (GRCm39) |
T1874A |
possibly damaging |
Het |
| Rftn1 |
C |
A |
17: 50,476,173 (GRCm39) |
M1I |
probably null |
Het |
| Ros1 |
T |
A |
10: 52,042,175 (GRCm39) |
Q250L |
probably damaging |
Het |
| Slc11a1 |
T |
A |
1: 74,419,824 (GRCm39) |
F166I |
probably damaging |
Het |
| Slc17a9 |
A |
G |
2: 180,373,755 (GRCm39) |
T59A |
probably benign |
Het |
| Slc26a5 |
T |
C |
5: 22,028,476 (GRCm39) |
K364R |
probably damaging |
Het |
| Slitrk2 |
T |
C |
X: 65,698,754 (GRCm39) |
I415T |
probably damaging |
Het |
| Stom |
A |
G |
2: 35,211,613 (GRCm39) |
I136T |
possibly damaging |
Het |
| Strc |
G |
T |
2: 121,195,004 (GRCm39) |
P1728T |
probably damaging |
Het |
| Telo2 |
C |
A |
17: 25,322,673 (GRCm39) |
V640F |
probably benign |
Het |
| Tg |
T |
C |
15: 66,553,782 (GRCm39) |
V399A |
probably benign |
Het |
| Tmem214 |
A |
G |
5: 31,030,975 (GRCm39) |
K383E |
possibly damaging |
Het |
| Tomm40l |
A |
T |
1: 171,049,550 (GRCm39) |
L13* |
probably null |
Het |
| Tonsl |
A |
T |
15: 76,518,840 (GRCm39) |
N526K |
probably damaging |
Het |
| Top2b |
T |
G |
14: 16,409,189 (GRCm38) |
I777M |
probably damaging |
Het |
| Tymp |
T |
A |
15: 89,258,965 (GRCm39) |
M240L |
probably benign |
Het |
| Ubr2 |
A |
T |
17: 47,296,968 (GRCm39) |
S271T |
possibly damaging |
Het |
| Uggt2 |
A |
T |
14: 119,312,749 (GRCm39) |
N353K |
probably damaging |
Het |
| Ugt2b35 |
T |
A |
5: 87,151,191 (GRCm39) |
F266I |
possibly damaging |
Het |
| Vmn2r103 |
C |
T |
17: 20,013,909 (GRCm39) |
R234W |
probably damaging |
Het |
| Zfp109 |
C |
A |
7: 23,927,886 (GRCm39) |
D508Y |
probably damaging |
Het |
| Zfp623 |
T |
C |
15: 75,819,379 (GRCm39) |
S112P |
possibly damaging |
Het |
| Zfp735 |
A |
G |
11: 73,601,851 (GRCm39) |
N265S |
possibly damaging |
Het |
| Zfp879 |
A |
G |
11: 50,724,094 (GRCm39) |
C321R |
probably damaging |
Het |
|
| Other mutations in Adamts16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01024:Adamts16
|
APN |
13 |
70,943,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01338:Adamts16
|
APN |
13 |
70,984,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Adamts16
|
APN |
13 |
70,941,260 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01804:Adamts16
|
APN |
13 |
70,949,080 (GRCm39) |
nonsense |
probably null |
|
|
IGL01874:Adamts16
|
APN |
13 |
70,916,823 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01984:Adamts16
|
APN |
13 |
70,935,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02305:Adamts16
|
APN |
13 |
70,921,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02350:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02357:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02429:Adamts16
|
APN |
13 |
70,935,289 (GRCm39) |
splice site |
probably benign |
|
|
IGL02450:Adamts16
|
APN |
13 |
70,984,419 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02807:Adamts16
|
APN |
13 |
70,886,897 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03356:Adamts16
|
APN |
13 |
70,901,410 (GRCm39) |
missense |
probably benign |
0.00 |
|
swap
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
switcheroo
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0201:Adamts16
|
UTSW |
13 |
70,927,763 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0326:Adamts16
|
UTSW |
13 |
70,927,730 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0336:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R0369:Adamts16
|
UTSW |
13 |
70,927,671 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0422:Adamts16
|
UTSW |
13 |
70,887,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0507:Adamts16
|
UTSW |
13 |
70,916,766 (GRCm39) |
missense |
probably benign |
|
|
R0524:Adamts16
|
UTSW |
13 |
70,949,013 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0590:Adamts16
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0734:Adamts16
|
UTSW |
13 |
70,886,600 (GRCm39) |
splice site |
probably benign |
|
|
R0787:Adamts16
|
UTSW |
13 |
70,886,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0826:Adamts16
|
UTSW |
13 |
70,916,811 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0920:Adamts16
|
UTSW |
13 |
70,911,680 (GRCm39) |
splice site |
probably benign |
|
|
R1027:Adamts16
|
UTSW |
13 |
70,915,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1535:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1617:Adamts16
|
UTSW |
13 |
70,946,154 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1700:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1734:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1736:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1737:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1738:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1746:Adamts16
|
UTSW |
13 |
70,927,717 (GRCm39) |
splice site |
probably null |
|
|
R1869:Adamts16
|
UTSW |
13 |
70,883,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1944:Adamts16
|
UTSW |
13 |
70,940,005 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1997:Adamts16
|
UTSW |
13 |
70,901,386 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2018:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2135:Adamts16
|
UTSW |
13 |
70,949,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2228:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R3410:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3411:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3842:Adamts16
|
UTSW |
13 |
70,887,010 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4117:Adamts16
|
UTSW |
13 |
70,916,111 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4435:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4436:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4526:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4552:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4555:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4556:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4557:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4579:Adamts16
|
UTSW |
13 |
70,927,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4639:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4640:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4641:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4642:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4672:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R5350:Adamts16
|
UTSW |
13 |
70,901,315 (GRCm39) |
nonsense |
probably null |
|
|
R5464:Adamts16
|
UTSW |
13 |
70,909,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5613:Adamts16
|
UTSW |
13 |
70,878,253 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5667:Adamts16
|
UTSW |
13 |
70,984,494 (GRCm39) |
nonsense |
probably null |
|
|
R5735:Adamts16
|
UTSW |
13 |
70,984,337 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5762:Adamts16
|
UTSW |
13 |
70,886,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Adamts16
|
UTSW |
13 |
70,877,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6169:Adamts16
|
UTSW |
13 |
70,918,393 (GRCm39) |
nonsense |
probably null |
|
|
R6351:Adamts16
|
UTSW |
13 |
70,984,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6665:Adamts16
|
UTSW |
13 |
70,927,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6913:Adamts16
|
UTSW |
13 |
70,877,017 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6982:Adamts16
|
UTSW |
13 |
70,916,639 (GRCm39) |
splice site |
probably null |
|
|
R6996:Adamts16
|
UTSW |
13 |
70,946,157 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7313:Adamts16
|
UTSW |
13 |
70,921,074 (GRCm39) |
nonsense |
probably null |
|
|
R7356:Adamts16
|
UTSW |
13 |
70,984,399 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7509:Adamts16
|
UTSW |
13 |
70,935,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Adamts16
|
UTSW |
13 |
70,878,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Adamts16
|
UTSW |
13 |
70,984,265 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7968:Adamts16
|
UTSW |
13 |
70,886,701 (GRCm39) |
missense |
probably benign |
|
|
R8231:Adamts16
|
UTSW |
13 |
70,925,599 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8232:Adamts16
|
UTSW |
13 |
70,941,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8470:Adamts16
|
UTSW |
13 |
70,984,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Adamts16
|
UTSW |
13 |
70,886,794 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8772:Adamts16
|
UTSW |
13 |
70,984,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Adamts16
|
UTSW |
13 |
70,941,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8921:Adamts16
|
UTSW |
13 |
70,939,910 (GRCm39) |
splice site |
probably benign |
|
|
R8973:Adamts16
|
UTSW |
13 |
70,886,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9132:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9149:Adamts16
|
UTSW |
13 |
70,883,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9159:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9312:Adamts16
|
UTSW |
13 |
70,949,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Adamts16
|
UTSW |
13 |
70,949,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adamts16
|
UTSW |
13 |
70,909,892 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTGAGCTCCCAAATGAAAGCTG -3'
(R):5'- TCATCAAATTGCATGGGAAAGG -3'
Sequencing Primer
(F):5'- AAAAGTATCTCCCATCATCTGCTCCG -3'
(R):5'- GGTCATATATCCCTTGGTAACTCATC -3'
|
| Posted On |
2014-10-15 |
Incidental Mutation