Incidental Mutation 'R2267:Kcnt2'
| ID |
242085 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kcnt2
|
| Ensembl Gene |
ENSMUSG00000052726 |
| Gene Name |
potassium channel, subfamily T, member 2 |
| Synonyms |
E330038N15Rik |
| MMRRC Submission |
040267-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.099)
|
| Stock # |
R2267 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
140173896-140539805 bp(+) (GRCm39) |
| Type of Mutation |
splice site (5 bp from exon) |
| DNA Base Change (assembly) |
G to A
at 140501421 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113333
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000119786]
[ENSMUST00000119786]
[ENSMUST00000120709]
[ENSMUST00000120709]
[ENSMUST00000120796]
[ENSMUST00000120796]
|
| AlphaFold |
D3Z649 |
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000054623
Gene: ENSMUSG00000052726
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
64 |
83 |
N/A |
INTRINSIC |
|
transmembrane domain
|
103 |
125 |
N/A |
INTRINSIC |
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans_2
|
199 |
282 |
2.8e-15 |
PFAM |
|
Pfam:BK_channel_a
|
424 |
533 |
1.3e-31 |
PFAM |
|
low complexity region
|
655 |
670 |
N/A |
INTRINSIC |
|
low complexity region
|
677 |
689 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000119786
|
| SMART Domains |
Protein: ENSMUSP00000113535
Gene: ENSMUSG00000052726
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
64 |
83 |
N/A |
INTRINSIC |
|
transmembrane domain
|
103 |
125 |
N/A |
INTRINSIC |
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans_2
|
199 |
282 |
2.6e-15 |
PFAM |
|
Pfam:BK_channel_a
|
422 |
476 |
2.3e-16 |
PFAM |
|
low complexity region
|
598 |
613 |
N/A |
INTRINSIC |
|
low complexity region
|
620 |
632 |
N/A |
INTRINSIC |
|
low complexity region
|
699 |
714 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000119786
|
| SMART Domains |
Protein: ENSMUSP00000113535
Gene: ENSMUSG00000052726
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
64 |
83 |
N/A |
INTRINSIC |
|
transmembrane domain
|
103 |
125 |
N/A |
INTRINSIC |
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans_2
|
199 |
282 |
2.6e-15 |
PFAM |
|
Pfam:BK_channel_a
|
422 |
476 |
2.3e-16 |
PFAM |
|
low complexity region
|
598 |
613 |
N/A |
INTRINSIC |
|
low complexity region
|
620 |
632 |
N/A |
INTRINSIC |
|
low complexity region
|
699 |
714 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120709
|
| SMART Domains |
Protein: ENSMUSP00000112887
Gene: ENSMUSG00000052726
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
64 |
83 |
N/A |
INTRINSIC |
|
transmembrane domain
|
103 |
125 |
N/A |
INTRINSIC |
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans_2
|
199 |
282 |
2.7e-15 |
PFAM |
|
Pfam:BK_channel_a
|
422 |
527 |
1.5e-39 |
PFAM |
|
low complexity region
|
648 |
663 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
682 |
N/A |
INTRINSIC |
|
low complexity region
|
749 |
764 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120709
|
| SMART Domains |
Protein: ENSMUSP00000112887
Gene: ENSMUSG00000052726
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
64 |
83 |
N/A |
INTRINSIC |
|
transmembrane domain
|
103 |
125 |
N/A |
INTRINSIC |
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans_2
|
199 |
282 |
2.7e-15 |
PFAM |
|
Pfam:BK_channel_a
|
422 |
527 |
1.5e-39 |
PFAM |
|
low complexity region
|
648 |
663 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
682 |
N/A |
INTRINSIC |
|
low complexity region
|
749 |
764 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120796
|
| SMART Domains |
Protein: ENSMUSP00000113333
Gene: ENSMUSG00000052726
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
64 |
83 |
N/A |
INTRINSIC |
|
transmembrane domain
|
103 |
125 |
N/A |
INTRINSIC |
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans_2
|
199 |
282 |
2.8e-15 |
PFAM |
|
Pfam:BK_channel_a
|
422 |
527 |
1.5e-39 |
PFAM |
|
low complexity region
|
648 |
663 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
682 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000120796
|
| SMART Domains |
Protein: ENSMUSP00000113333
Gene: ENSMUSG00000052726
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
64 |
83 |
N/A |
INTRINSIC |
|
transmembrane domain
|
103 |
125 |
N/A |
INTRINSIC |
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans_2
|
199 |
282 |
2.8e-15 |
PFAM |
|
Pfam:BK_channel_a
|
422 |
527 |
1.5e-39 |
PFAM |
|
low complexity region
|
648 |
663 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
682 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193606
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000193820
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
98% (108/110) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele are viable with normal pain and itch responses. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadac |
T |
A |
3: 59,944,737 (GRCm39) |
D136E |
probably damaging |
Het |
| Abca16 |
A |
G |
7: 120,030,383 (GRCm39) |
D165G |
probably benign |
Het |
| Abca8b |
G |
A |
11: 109,845,974 (GRCm39) |
T820M |
probably benign |
Het |
| Acot2 |
C |
T |
12: 84,037,334 (GRCm39) |
A216V |
probably damaging |
Het |
| Agap2 |
T |
A |
10: 126,918,297 (GRCm39) |
|
probably benign |
Het |
| Ak7 |
T |
C |
12: 105,713,473 (GRCm39) |
V419A |
probably benign |
Het |
| Apmap |
A |
G |
2: 150,430,821 (GRCm39) |
|
probably null |
Het |
| Apob |
T |
C |
12: 8,065,475 (GRCm39) |
F4115S |
possibly damaging |
Het |
| Cachd1 |
T |
A |
4: 100,806,266 (GRCm39) |
|
probably benign |
Het |
| Ccdc39 |
T |
A |
3: 33,869,633 (GRCm39) |
E731D |
probably damaging |
Het |
| Ces2a |
A |
T |
8: 105,466,822 (GRCm39) |
I65F |
probably benign |
Het |
| Commd8 |
A |
G |
5: 72,322,765 (GRCm39) |
W51R |
probably damaging |
Het |
| D2hgdh |
C |
T |
1: 93,763,157 (GRCm39) |
A314V |
probably damaging |
Het |
| Dcun1d4 |
T |
A |
5: 73,638,618 (GRCm39) |
|
probably benign |
Het |
| Dgke |
T |
A |
11: 88,943,295 (GRCm39) |
E231D |
probably benign |
Het |
| Dhrs9 |
A |
G |
2: 69,223,197 (GRCm39) |
|
probably benign |
Het |
| Dhx30 |
C |
T |
9: 109,916,102 (GRCm39) |
G662R |
probably damaging |
Het |
| Dipk2b |
A |
G |
X: 18,289,926 (GRCm39) |
S179P |
possibly damaging |
Het |
| Dnah7b |
T |
A |
1: 46,273,075 (GRCm39) |
M2401K |
probably damaging |
Het |
| Dnmt3a |
T |
A |
12: 3,947,551 (GRCm39) |
|
probably null |
Het |
| Dst |
C |
T |
1: 34,334,547 (GRCm39) |
T4874I |
probably damaging |
Het |
| Eef2kmt |
G |
A |
16: 5,073,804 (GRCm39) |
|
probably benign |
Het |
| Ess2 |
T |
C |
16: 17,727,859 (GRCm39) |
T107A |
probably damaging |
Het |
| Etfa |
A |
T |
9: 55,394,015 (GRCm39) |
L212Q |
probably damaging |
Het |
| Exosc5 |
T |
C |
7: 25,363,809 (GRCm39) |
L107P |
possibly damaging |
Het |
| Fam117b |
T |
C |
1: 59,952,789 (GRCm39) |
L156P |
probably damaging |
Het |
| Fam186b |
T |
G |
15: 99,183,524 (GRCm39) |
D40A |
probably damaging |
Het |
| Fga |
T |
C |
3: 82,940,257 (GRCm39) |
L637P |
probably damaging |
Het |
| Foxn4 |
T |
C |
5: 114,393,662 (GRCm39) |
T486A |
probably damaging |
Het |
| Gcc1 |
A |
G |
6: 28,418,498 (GRCm39) |
S612P |
probably benign |
Het |
| Gjd3 |
C |
T |
11: 98,873,227 (GRCm39) |
V206M |
probably damaging |
Het |
| Gpam |
A |
T |
19: 55,061,142 (GRCm39) |
|
probably null |
Het |
| Gpc6 |
A |
T |
14: 118,125,932 (GRCm39) |
|
probably null |
Het |
| Gphb5 |
C |
G |
12: 75,459,720 (GRCm39) |
V92L |
probably benign |
Het |
| Grid2ip |
C |
T |
5: 143,371,847 (GRCm39) |
P690L |
probably benign |
Het |
| Gsdmc |
T |
C |
15: 63,648,647 (GRCm39) |
E429G |
probably benign |
Het |
| H2bc9 |
T |
C |
13: 23,727,162 (GRCm39) |
K121E |
possibly damaging |
Het |
| Heatr5a |
T |
C |
12: 51,940,528 (GRCm39) |
D1444G |
possibly damaging |
Het |
| Hmcn1 |
T |
C |
1: 150,474,761 (GRCm39) |
S4709G |
probably benign |
Het |
| Hr |
A |
T |
14: 70,795,547 (GRCm39) |
D393V |
probably benign |
Het |
| Ido2 |
T |
C |
8: 25,025,268 (GRCm39) |
Y253C |
probably damaging |
Het |
| Itgal |
A |
G |
7: 126,905,873 (GRCm39) |
I352V |
possibly damaging |
Het |
| Itih4 |
A |
G |
14: 30,614,385 (GRCm39) |
D445G |
probably damaging |
Het |
| Kcnh8 |
GAGACCAACGAGCAGCTGATGCTTCAGA |
GAGA |
17: 53,032,934 (GRCm39) |
74 |
probably benign |
Het |
| Klk1b21 |
T |
C |
7: 43,753,863 (GRCm39) |
I49T |
possibly damaging |
Het |
| Klrb1 |
A |
T |
6: 128,699,937 (GRCm39) |
S25T |
probably damaging |
Het |
| L3mbtl3 |
C |
T |
10: 26,207,755 (GRCm39) |
W321* |
probably null |
Het |
| Lama2 |
T |
A |
10: 26,868,932 (GRCm39) |
I2838F |
probably damaging |
Het |
| Lrrtm1 |
C |
A |
6: 77,220,996 (GRCm39) |
A151E |
probably damaging |
Het |
| Lsmem1 |
GTACATACATACATACATACATACATACA |
GTACATACATACATACATACATACATACATACA |
12: 40,235,260 (GRCm39) |
|
probably null |
Het |
| Magi3 |
G |
A |
3: 103,928,382 (GRCm39) |
|
probably benign |
Het |
| Mamdc2 |
A |
T |
19: 23,281,267 (GRCm39) |
|
probably benign |
Het |
| Mcc |
T |
C |
18: 44,652,608 (GRCm39) |
D272G |
probably damaging |
Het |
| Mgst3 |
T |
A |
1: 167,201,368 (GRCm39) |
T106S |
probably benign |
Het |
| Mink1 |
G |
A |
11: 70,492,550 (GRCm39) |
|
probably null |
Het |
| Mlh3 |
G |
T |
12: 85,307,585 (GRCm39) |
H1181N |
possibly damaging |
Het |
| Mmrn2 |
A |
G |
14: 34,121,449 (GRCm39) |
K773R |
probably benign |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Mro |
T |
C |
18: 74,006,368 (GRCm39) |
I104T |
probably benign |
Het |
| Mtbp |
G |
A |
15: 55,432,556 (GRCm39) |
|
probably null |
Het |
| Mtss2 |
A |
G |
8: 111,455,362 (GRCm39) |
K92E |
possibly damaging |
Het |
| Mybphl |
A |
G |
3: 108,272,317 (GRCm39) |
E2G |
probably damaging |
Het |
| Nbeal1 |
T |
A |
1: 60,370,037 (GRCm39) |
|
probably benign |
Het |
| Neurod2 |
C |
A |
11: 98,218,582 (GRCm39) |
C194F |
probably damaging |
Het |
| Nr4a2 |
T |
A |
2: 57,002,018 (GRCm39) |
D145V |
possibly damaging |
Het |
| Ntmt1 |
C |
A |
2: 30,710,472 (GRCm39) |
N58K |
probably benign |
Het |
| Nup205 |
T |
C |
6: 35,218,284 (GRCm39) |
S1819P |
possibly damaging |
Het |
| Obsl1 |
T |
C |
1: 75,482,342 (GRCm39) |
H176R |
probably damaging |
Het |
| Or51f1d |
G |
A |
7: 102,701,344 (GRCm39) |
V280I |
probably benign |
Het |
| Or7g21 |
A |
T |
9: 19,032,737 (GRCm39) |
H162L |
probably benign |
Het |
| Or8d2b |
A |
G |
9: 38,789,359 (GRCm39) |
T296A |
probably benign |
Het |
| P2ry13 |
T |
C |
3: 59,117,449 (GRCm39) |
M110V |
probably damaging |
Het |
| P2ry14 |
T |
C |
3: 59,022,992 (GRCm39) |
N165S |
probably damaging |
Het |
| Phka1 |
A |
G |
X: 101,584,716 (GRCm39) |
|
probably benign |
Het |
| Plxnd1 |
A |
G |
6: 115,939,704 (GRCm39) |
V1425A |
probably benign |
Het |
| Ppp2ca |
G |
A |
11: 52,008,913 (GRCm39) |
G138R |
probably damaging |
Het |
| Ptpn12 |
A |
T |
5: 21,203,409 (GRCm39) |
N456K |
probably damaging |
Het |
| Scarb1 |
A |
T |
5: 125,364,439 (GRCm39) |
S97T |
possibly damaging |
Het |
| Scyl1 |
C |
T |
19: 5,811,749 (GRCm39) |
D440N |
possibly damaging |
Het |
| Sema5a |
C |
A |
15: 32,575,065 (GRCm39) |
T391K |
probably benign |
Het |
| Sipa1l3 |
T |
A |
7: 29,099,027 (GRCm39) |
N414I |
probably damaging |
Het |
| Skint6 |
T |
C |
4: 112,700,019 (GRCm39) |
|
probably null |
Het |
| Slc35a3 |
T |
C |
3: 116,467,285 (GRCm39) |
K325E |
possibly damaging |
Het |
| Spag17 |
C |
A |
3: 99,969,182 (GRCm39) |
|
probably null |
Het |
| Spib |
T |
A |
7: 44,178,348 (GRCm39) |
M141L |
probably benign |
Het |
| Srebf1 |
A |
G |
11: 60,097,973 (GRCm39) |
S44P |
probably damaging |
Het |
| Styk1 |
T |
C |
6: 131,289,539 (GRCm39) |
E25G |
probably benign |
Het |
| Taar8b |
T |
C |
10: 23,967,270 (GRCm39) |
N308S |
probably damaging |
Het |
| Taf15 |
T |
G |
11: 83,388,088 (GRCm39) |
S200R |
probably damaging |
Het |
| Tanc1 |
G |
A |
2: 59,667,563 (GRCm39) |
|
probably null |
Het |
| Tas2r134 |
A |
G |
2: 51,518,249 (GRCm39) |
T243A |
probably benign |
Het |
| Tatdn1 |
A |
T |
15: 58,777,601 (GRCm39) |
M218K |
probably damaging |
Het |
| Tbc1d14 |
A |
G |
5: 36,700,561 (GRCm39) |
L269P |
possibly damaging |
Het |
| Tbx1 |
T |
C |
16: 18,400,744 (GRCm39) |
|
probably null |
Het |
| Tgfbr3l |
A |
G |
8: 4,300,506 (GRCm39) |
E228G |
probably benign |
Het |
| Tmem233 |
G |
C |
5: 116,189,517 (GRCm39) |
|
probably benign |
Het |
| Tmprss11d |
A |
G |
5: 86,521,208 (GRCm39) |
Y2H |
probably benign |
Het |
| Trps1 |
G |
A |
15: 50,685,794 (GRCm39) |
R544C |
probably damaging |
Het |
| Ttc22 |
T |
C |
4: 106,496,282 (GRCm39) |
V444A |
possibly damaging |
Het |
| Ttc28 |
A |
G |
5: 111,373,869 (GRCm39) |
T1071A |
possibly damaging |
Het |
| Tymp |
A |
T |
15: 89,258,011 (GRCm39) |
V378D |
probably damaging |
Het |
| Ube2j1 |
T |
A |
4: 33,049,943 (GRCm39) |
F257I |
possibly damaging |
Het |
| Vmn2r18 |
T |
C |
5: 151,510,127 (GRCm39) |
E82G |
probably damaging |
Het |
| Wwp1 |
T |
C |
4: 19,638,618 (GRCm39) |
D575G |
probably damaging |
Het |
|
| Other mutations in Kcnt2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Kcnt2
|
APN |
1 |
140,450,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00673:Kcnt2
|
APN |
1 |
140,523,789 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
IGL00806:Kcnt2
|
APN |
1 |
140,450,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01135:Kcnt2
|
APN |
1 |
140,282,293 (GRCm39) |
critical splice donor site |
probably null |
0.00 |
|
IGL01412:Kcnt2
|
APN |
1 |
140,498,155 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01777:Kcnt2
|
APN |
1 |
140,523,736 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01780:Kcnt2
|
APN |
1 |
140,279,007 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02134:Kcnt2
|
APN |
1 |
140,304,121 (GRCm39) |
missense |
probably benign |
|
|
IGL02350:Kcnt2
|
APN |
1 |
140,279,007 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02357:Kcnt2
|
APN |
1 |
140,279,007 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02481:Kcnt2
|
APN |
1 |
140,282,299 (GRCm39) |
splice site |
probably benign |
|
|
IGL02483:Kcnt2
|
APN |
1 |
140,282,299 (GRCm39) |
splice site |
probably benign |
|
|
IGL02866:Kcnt2
|
APN |
1 |
140,352,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02891:Kcnt2
|
APN |
1 |
140,502,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03007:Kcnt2
|
APN |
1 |
140,282,245 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL03024:Kcnt2
|
APN |
1 |
140,498,193 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03231:Kcnt2
|
APN |
1 |
140,461,740 (GRCm39) |
intron |
probably benign |
|
|
BB002:Kcnt2
|
UTSW |
1 |
140,282,247 (GRCm39) |
nonsense |
probably null |
|
|
BB012:Kcnt2
|
UTSW |
1 |
140,282,247 (GRCm39) |
nonsense |
probably null |
|
|
R0230:Kcnt2
|
UTSW |
1 |
140,174,083 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0367:Kcnt2
|
UTSW |
1 |
140,278,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0486:Kcnt2
|
UTSW |
1 |
140,437,218 (GRCm39) |
nonsense |
probably null |
|
|
R0543:Kcnt2
|
UTSW |
1 |
140,537,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0849:Kcnt2
|
UTSW |
1 |
140,435,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1123:Kcnt2
|
UTSW |
1 |
140,501,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1156:Kcnt2
|
UTSW |
1 |
140,356,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1425:Kcnt2
|
UTSW |
1 |
140,310,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Kcnt2
|
UTSW |
1 |
140,411,970 (GRCm39) |
nonsense |
probably null |
|
|
R1546:Kcnt2
|
UTSW |
1 |
140,359,116 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1728:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1729:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1730:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1739:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1762:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1783:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1784:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1785:Kcnt2
|
UTSW |
1 |
140,282,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1862:Kcnt2
|
UTSW |
1 |
140,353,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1887:Kcnt2
|
UTSW |
1 |
140,511,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1889:Kcnt2
|
UTSW |
1 |
140,512,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1894:Kcnt2
|
UTSW |
1 |
140,353,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2005:Kcnt2
|
UTSW |
1 |
140,480,756 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2044:Kcnt2
|
UTSW |
1 |
140,302,892 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2115:Kcnt2
|
UTSW |
1 |
140,480,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2135:Kcnt2
|
UTSW |
1 |
140,356,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Kcnt2
|
UTSW |
1 |
140,437,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2212:Kcnt2
|
UTSW |
1 |
140,458,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2442:Kcnt2
|
UTSW |
1 |
140,304,091 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R3121:Kcnt2
|
UTSW |
1 |
140,356,622 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3176:Kcnt2
|
UTSW |
1 |
140,537,377 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3276:Kcnt2
|
UTSW |
1 |
140,537,377 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3704:Kcnt2
|
UTSW |
1 |
140,461,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Kcnt2
|
UTSW |
1 |
140,512,025 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4164:Kcnt2
|
UTSW |
1 |
140,537,368 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4201:Kcnt2
|
UTSW |
1 |
140,353,070 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4501:Kcnt2
|
UTSW |
1 |
140,480,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4502:Kcnt2
|
UTSW |
1 |
140,435,485 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4632:Kcnt2
|
UTSW |
1 |
140,450,886 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4758:Kcnt2
|
UTSW |
1 |
140,446,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4790:Kcnt2
|
UTSW |
1 |
140,282,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4892:Kcnt2
|
UTSW |
1 |
140,440,763 (GRCm39) |
nonsense |
probably null |
|
|
R4973:Kcnt2
|
UTSW |
1 |
140,537,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5154:Kcnt2
|
UTSW |
1 |
140,278,994 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5296:Kcnt2
|
UTSW |
1 |
140,537,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5353:Kcnt2
|
UTSW |
1 |
140,354,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Kcnt2
|
UTSW |
1 |
140,502,481 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R5806:Kcnt2
|
UTSW |
1 |
140,437,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5887:Kcnt2
|
UTSW |
1 |
140,353,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5917:Kcnt2
|
UTSW |
1 |
140,461,666 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5961:Kcnt2
|
UTSW |
1 |
140,435,440 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6123:Kcnt2
|
UTSW |
1 |
140,290,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6225:Kcnt2
|
UTSW |
1 |
140,354,661 (GRCm39) |
nonsense |
probably null |
|
|
R6248:Kcnt2
|
UTSW |
1 |
140,437,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6351:Kcnt2
|
UTSW |
1 |
140,302,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6380:Kcnt2
|
UTSW |
1 |
140,437,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6532:Kcnt2
|
UTSW |
1 |
140,511,844 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6693:Kcnt2
|
UTSW |
1 |
140,278,965 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6817:Kcnt2
|
UTSW |
1 |
140,173,931 (GRCm39) |
unclassified |
probably benign |
|
|
R6856:Kcnt2
|
UTSW |
1 |
140,523,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6944:Kcnt2
|
UTSW |
1 |
140,511,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6971:Kcnt2
|
UTSW |
1 |
140,440,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7052:Kcnt2
|
UTSW |
1 |
140,310,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7138:Kcnt2
|
UTSW |
1 |
140,523,778 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7261:Kcnt2
|
UTSW |
1 |
140,282,255 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7474:Kcnt2
|
UTSW |
1 |
140,498,216 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7524:Kcnt2
|
UTSW |
1 |
140,511,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7541:Kcnt2
|
UTSW |
1 |
140,304,122 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7558:Kcnt2
|
UTSW |
1 |
140,450,928 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7651:Kcnt2
|
UTSW |
1 |
140,498,199 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7730:Kcnt2
|
UTSW |
1 |
140,446,686 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7875:Kcnt2
|
UTSW |
1 |
140,501,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7883:Kcnt2
|
UTSW |
1 |
140,450,888 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7925:Kcnt2
|
UTSW |
1 |
140,282,247 (GRCm39) |
nonsense |
probably null |
|
|
R8040:Kcnt2
|
UTSW |
1 |
140,377,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8041:Kcnt2
|
UTSW |
1 |
140,537,398 (GRCm39) |
missense |
probably benign |
|
|
R8171:Kcnt2
|
UTSW |
1 |
140,437,203 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8268:Kcnt2
|
UTSW |
1 |
140,450,954 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8905:Kcnt2
|
UTSW |
1 |
140,435,467 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8927:Kcnt2
|
UTSW |
1 |
140,356,535 (GRCm39) |
splice site |
probably null |
|
|
R8988:Kcnt2
|
UTSW |
1 |
140,356,587 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9020:Kcnt2
|
UTSW |
1 |
140,512,049 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9109:Kcnt2
|
UTSW |
1 |
140,353,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9167:Kcnt2
|
UTSW |
1 |
140,506,200 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9232:Kcnt2
|
UTSW |
1 |
140,411,931 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9297:Kcnt2
|
UTSW |
1 |
140,352,933 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9298:Kcnt2
|
UTSW |
1 |
140,353,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9318:Kcnt2
|
UTSW |
1 |
140,352,933 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9404:Kcnt2
|
UTSW |
1 |
140,353,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Kcnt2
|
UTSW |
1 |
140,440,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
Z1088:Kcnt2
|
UTSW |
1 |
140,511,896 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Kcnt2
|
UTSW |
1 |
140,501,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Kcnt2
|
UTSW |
1 |
140,304,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Kcnt2
|
UTSW |
1 |
140,537,386 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCAAGGCTTACTGAGATGCTAG -3'
(R):5'- GCTGATGGACATTGTCATTGTC -3'
Sequencing Primer
(F):5'- CTGAGATGCTAGAAATAGATTTCCAG -3'
(R):5'- CTTGGACATGTCATTGTCAAAACTG -3'
|
| Posted On |
2014-10-16 |
Incidental Mutation