Incidental Mutation 'R2267:Skint6'
| ID |
242107 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Skint6
|
| Ensembl Gene |
ENSMUSG00000087194 |
| Gene Name |
selection and upkeep of intraepithelial T cells 6 |
| Synonyms |
OTTMUSG00000008519 |
| MMRRC Submission |
040267-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.066)
|
| Stock # |
R2267 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
112661813-113144170 bp(-) (GRCm39) |
| Type of Mutation |
splice site (83 bp from exon) |
| DNA Base Change (assembly) |
T to C
at 112700019 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132312
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000138966]
[ENSMUST00000171224]
|
| AlphaFold |
A7XUZ6 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000138966
|
| SMART Domains |
Protein: ENSMUSP00000121870
Gene: ENSMUSG00000087194
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
IGv
|
44 |
125 |
2.32e-8 |
SMART |
|
internal_repeat_1
|
219 |
594 |
1.11e-41 |
PROSPERO |
|
low complexity region
|
601 |
610 |
N/A |
INTRINSIC |
|
low complexity region
|
678 |
690 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
701 |
1076 |
1.11e-41 |
PROSPERO |
|
transmembrane domain
|
1087 |
1104 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1164 |
1186 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1206 |
1228 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000171224
|
| SMART Domains |
Protein: ENSMUSP00000132312
Gene: ENSMUSG00000087194
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
IGv
|
44 |
125 |
2.32e-8 |
SMART |
|
internal_repeat_1
|
219 |
594 |
1.11e-41 |
PROSPERO |
|
low complexity region
|
601 |
610 |
N/A |
INTRINSIC |
|
low complexity region
|
678 |
690 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
701 |
1076 |
1.11e-41 |
PROSPERO |
|
transmembrane domain
|
1087 |
1104 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1164 |
1186 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1206 |
1228 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
98% (108/110) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadac |
T |
A |
3: 59,944,737 (GRCm39) |
D136E |
probably damaging |
Het |
| Abca16 |
A |
G |
7: 120,030,383 (GRCm39) |
D165G |
probably benign |
Het |
| Abca8b |
G |
A |
11: 109,845,974 (GRCm39) |
T820M |
probably benign |
Het |
| Acot2 |
C |
T |
12: 84,037,334 (GRCm39) |
A216V |
probably damaging |
Het |
| Agap2 |
T |
A |
10: 126,918,297 (GRCm39) |
|
probably benign |
Het |
| Ak7 |
T |
C |
12: 105,713,473 (GRCm39) |
V419A |
probably benign |
Het |
| Apmap |
A |
G |
2: 150,430,821 (GRCm39) |
|
probably null |
Het |
| Apob |
T |
C |
12: 8,065,475 (GRCm39) |
F4115S |
possibly damaging |
Het |
| Cachd1 |
T |
A |
4: 100,806,266 (GRCm39) |
|
probably benign |
Het |
| Ccdc39 |
T |
A |
3: 33,869,633 (GRCm39) |
E731D |
probably damaging |
Het |
| Ces2a |
A |
T |
8: 105,466,822 (GRCm39) |
I65F |
probably benign |
Het |
| Commd8 |
A |
G |
5: 72,322,765 (GRCm39) |
W51R |
probably damaging |
Het |
| D2hgdh |
C |
T |
1: 93,763,157 (GRCm39) |
A314V |
probably damaging |
Het |
| Dcun1d4 |
T |
A |
5: 73,638,618 (GRCm39) |
|
probably benign |
Het |
| Dgke |
T |
A |
11: 88,943,295 (GRCm39) |
E231D |
probably benign |
Het |
| Dhrs9 |
A |
G |
2: 69,223,197 (GRCm39) |
|
probably benign |
Het |
| Dhx30 |
C |
T |
9: 109,916,102 (GRCm39) |
G662R |
probably damaging |
Het |
| Dipk2b |
A |
G |
X: 18,289,926 (GRCm39) |
S179P |
possibly damaging |
Het |
| Dnah7b |
T |
A |
1: 46,273,075 (GRCm39) |
M2401K |
probably damaging |
Het |
| Dnmt3a |
T |
A |
12: 3,947,551 (GRCm39) |
|
probably null |
Het |
| Dst |
C |
T |
1: 34,334,547 (GRCm39) |
T4874I |
probably damaging |
Het |
| Eef2kmt |
G |
A |
16: 5,073,804 (GRCm39) |
|
probably benign |
Het |
| Ess2 |
T |
C |
16: 17,727,859 (GRCm39) |
T107A |
probably damaging |
Het |
| Etfa |
A |
T |
9: 55,394,015 (GRCm39) |
L212Q |
probably damaging |
Het |
| Exosc5 |
T |
C |
7: 25,363,809 (GRCm39) |
L107P |
possibly damaging |
Het |
| Fam117b |
T |
C |
1: 59,952,789 (GRCm39) |
L156P |
probably damaging |
Het |
| Fam186b |
T |
G |
15: 99,183,524 (GRCm39) |
D40A |
probably damaging |
Het |
| Fga |
T |
C |
3: 82,940,257 (GRCm39) |
L637P |
probably damaging |
Het |
| Foxn4 |
T |
C |
5: 114,393,662 (GRCm39) |
T486A |
probably damaging |
Het |
| Gcc1 |
A |
G |
6: 28,418,498 (GRCm39) |
S612P |
probably benign |
Het |
| Gjd3 |
C |
T |
11: 98,873,227 (GRCm39) |
V206M |
probably damaging |
Het |
| Gpam |
A |
T |
19: 55,061,142 (GRCm39) |
|
probably null |
Het |
| Gpc6 |
A |
T |
14: 118,125,932 (GRCm39) |
|
probably null |
Het |
| Gphb5 |
C |
G |
12: 75,459,720 (GRCm39) |
V92L |
probably benign |
Het |
| Grid2ip |
C |
T |
5: 143,371,847 (GRCm39) |
P690L |
probably benign |
Het |
| Gsdmc |
T |
C |
15: 63,648,647 (GRCm39) |
E429G |
probably benign |
Het |
| H2bc9 |
T |
C |
13: 23,727,162 (GRCm39) |
K121E |
possibly damaging |
Het |
| Heatr5a |
T |
C |
12: 51,940,528 (GRCm39) |
D1444G |
possibly damaging |
Het |
| Hmcn1 |
T |
C |
1: 150,474,761 (GRCm39) |
S4709G |
probably benign |
Het |
| Hr |
A |
T |
14: 70,795,547 (GRCm39) |
D393V |
probably benign |
Het |
| Ido2 |
T |
C |
8: 25,025,268 (GRCm39) |
Y253C |
probably damaging |
Het |
| Itgal |
A |
G |
7: 126,905,873 (GRCm39) |
I352V |
possibly damaging |
Het |
| Itih4 |
A |
G |
14: 30,614,385 (GRCm39) |
D445G |
probably damaging |
Het |
| Kcnh8 |
GAGACCAACGAGCAGCTGATGCTTCAGA |
GAGA |
17: 53,032,934 (GRCm39) |
74 |
probably benign |
Het |
| Kcnt2 |
G |
A |
1: 140,501,421 (GRCm39) |
|
probably null |
Het |
| Klk1b21 |
T |
C |
7: 43,753,863 (GRCm39) |
I49T |
possibly damaging |
Het |
| Klrb1 |
A |
T |
6: 128,699,937 (GRCm39) |
S25T |
probably damaging |
Het |
| L3mbtl3 |
C |
T |
10: 26,207,755 (GRCm39) |
W321* |
probably null |
Het |
| Lama2 |
T |
A |
10: 26,868,932 (GRCm39) |
I2838F |
probably damaging |
Het |
| Lrrtm1 |
C |
A |
6: 77,220,996 (GRCm39) |
A151E |
probably damaging |
Het |
| Lsmem1 |
GTACATACATACATACATACATACATACA |
GTACATACATACATACATACATACATACATACA |
12: 40,235,260 (GRCm39) |
|
probably null |
Het |
| Magi3 |
G |
A |
3: 103,928,382 (GRCm39) |
|
probably benign |
Het |
| Mamdc2 |
A |
T |
19: 23,281,267 (GRCm39) |
|
probably benign |
Het |
| Mcc |
T |
C |
18: 44,652,608 (GRCm39) |
D272G |
probably damaging |
Het |
| Mgst3 |
T |
A |
1: 167,201,368 (GRCm39) |
T106S |
probably benign |
Het |
| Mink1 |
G |
A |
11: 70,492,550 (GRCm39) |
|
probably null |
Het |
| Mlh3 |
G |
T |
12: 85,307,585 (GRCm39) |
H1181N |
possibly damaging |
Het |
| Mmrn2 |
A |
G |
14: 34,121,449 (GRCm39) |
K773R |
probably benign |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Mro |
T |
C |
18: 74,006,368 (GRCm39) |
I104T |
probably benign |
Het |
| Mtbp |
G |
A |
15: 55,432,556 (GRCm39) |
|
probably null |
Het |
| Mtss2 |
A |
G |
8: 111,455,362 (GRCm39) |
K92E |
possibly damaging |
Het |
| Mybphl |
A |
G |
3: 108,272,317 (GRCm39) |
E2G |
probably damaging |
Het |
| Nbeal1 |
T |
A |
1: 60,370,037 (GRCm39) |
|
probably benign |
Het |
| Neurod2 |
C |
A |
11: 98,218,582 (GRCm39) |
C194F |
probably damaging |
Het |
| Nr4a2 |
T |
A |
2: 57,002,018 (GRCm39) |
D145V |
possibly damaging |
Het |
| Ntmt1 |
C |
A |
2: 30,710,472 (GRCm39) |
N58K |
probably benign |
Het |
| Nup205 |
T |
C |
6: 35,218,284 (GRCm39) |
S1819P |
possibly damaging |
Het |
| Obsl1 |
T |
C |
1: 75,482,342 (GRCm39) |
H176R |
probably damaging |
Het |
| Or51f1d |
G |
A |
7: 102,701,344 (GRCm39) |
V280I |
probably benign |
Het |
| Or7g21 |
A |
T |
9: 19,032,737 (GRCm39) |
H162L |
probably benign |
Het |
| Or8d2b |
A |
G |
9: 38,789,359 (GRCm39) |
T296A |
probably benign |
Het |
| P2ry13 |
T |
C |
3: 59,117,449 (GRCm39) |
M110V |
probably damaging |
Het |
| P2ry14 |
T |
C |
3: 59,022,992 (GRCm39) |
N165S |
probably damaging |
Het |
| Phka1 |
A |
G |
X: 101,584,716 (GRCm39) |
|
probably benign |
Het |
| Plxnd1 |
A |
G |
6: 115,939,704 (GRCm39) |
V1425A |
probably benign |
Het |
| Ppp2ca |
G |
A |
11: 52,008,913 (GRCm39) |
G138R |
probably damaging |
Het |
| Ptpn12 |
A |
T |
5: 21,203,409 (GRCm39) |
N456K |
probably damaging |
Het |
| Scarb1 |
A |
T |
5: 125,364,439 (GRCm39) |
S97T |
possibly damaging |
Het |
| Scyl1 |
C |
T |
19: 5,811,749 (GRCm39) |
D440N |
possibly damaging |
Het |
| Sema5a |
C |
A |
15: 32,575,065 (GRCm39) |
T391K |
probably benign |
Het |
| Sipa1l3 |
T |
A |
7: 29,099,027 (GRCm39) |
N414I |
probably damaging |
Het |
| Slc35a3 |
T |
C |
3: 116,467,285 (GRCm39) |
K325E |
possibly damaging |
Het |
| Spag17 |
C |
A |
3: 99,969,182 (GRCm39) |
|
probably null |
Het |
| Spib |
T |
A |
7: 44,178,348 (GRCm39) |
M141L |
probably benign |
Het |
| Srebf1 |
A |
G |
11: 60,097,973 (GRCm39) |
S44P |
probably damaging |
Het |
| Styk1 |
T |
C |
6: 131,289,539 (GRCm39) |
E25G |
probably benign |
Het |
| Taar8b |
T |
C |
10: 23,967,270 (GRCm39) |
N308S |
probably damaging |
Het |
| Taf15 |
T |
G |
11: 83,388,088 (GRCm39) |
S200R |
probably damaging |
Het |
| Tanc1 |
G |
A |
2: 59,667,563 (GRCm39) |
|
probably null |
Het |
| Tas2r134 |
A |
G |
2: 51,518,249 (GRCm39) |
T243A |
probably benign |
Het |
| Tatdn1 |
A |
T |
15: 58,777,601 (GRCm39) |
M218K |
probably damaging |
Het |
| Tbc1d14 |
A |
G |
5: 36,700,561 (GRCm39) |
L269P |
possibly damaging |
Het |
| Tbx1 |
T |
C |
16: 18,400,744 (GRCm39) |
|
probably null |
Het |
| Tgfbr3l |
A |
G |
8: 4,300,506 (GRCm39) |
E228G |
probably benign |
Het |
| Tmem233 |
G |
C |
5: 116,189,517 (GRCm39) |
|
probably benign |
Het |
| Tmprss11d |
A |
G |
5: 86,521,208 (GRCm39) |
Y2H |
probably benign |
Het |
| Trps1 |
G |
A |
15: 50,685,794 (GRCm39) |
R544C |
probably damaging |
Het |
| Ttc22 |
T |
C |
4: 106,496,282 (GRCm39) |
V444A |
possibly damaging |
Het |
| Ttc28 |
A |
G |
5: 111,373,869 (GRCm39) |
T1071A |
possibly damaging |
Het |
| Tymp |
A |
T |
15: 89,258,011 (GRCm39) |
V378D |
probably damaging |
Het |
| Ube2j1 |
T |
A |
4: 33,049,943 (GRCm39) |
F257I |
possibly damaging |
Het |
| Vmn2r18 |
T |
C |
5: 151,510,127 (GRCm39) |
E82G |
probably damaging |
Het |
| Wwp1 |
T |
C |
4: 19,638,618 (GRCm39) |
D575G |
probably damaging |
Het |
|
| Other mutations in Skint6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01123:Skint6
|
APN |
4 |
112,661,879 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01296:Skint6
|
APN |
4 |
113,093,637 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01343:Skint6
|
APN |
4 |
113,140,823 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL01543:Skint6
|
APN |
4 |
112,757,160 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL01633:Skint6
|
APN |
4 |
113,095,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01818:Skint6
|
APN |
4 |
112,805,766 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL02124:Skint6
|
APN |
4 |
112,944,993 (GRCm39) |
missense |
probably benign |
|
|
IGL02517:Skint6
|
APN |
4 |
112,805,737 (GRCm39) |
splice site |
probably benign |
|
|
IGL02647:Skint6
|
APN |
4 |
112,985,088 (GRCm39) |
splice site |
probably benign |
|
|
IGL02887:Skint6
|
APN |
4 |
113,095,381 (GRCm39) |
nonsense |
probably null |
|
|
IGL03026:Skint6
|
APN |
4 |
112,848,441 (GRCm39) |
splice site |
probably null |
|
|
IGL03030:Skint6
|
APN |
4 |
112,870,153 (GRCm39) |
missense |
probably benign |
0.03 |
|
meissner
|
UTSW |
4 |
112,661,891 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Tegmentum
|
UTSW |
4 |
112,700,019 (GRCm39) |
splice site |
probably null |
|
|
PIT4576001:Skint6
|
UTSW |
4 |
112,910,564 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0058:Skint6
|
UTSW |
4 |
112,904,012 (GRCm39) |
splice site |
probably benign |
|
|
R0058:Skint6
|
UTSW |
4 |
112,904,012 (GRCm39) |
splice site |
probably benign |
|
|
R0099:Skint6
|
UTSW |
4 |
112,668,698 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0158:Skint6
|
UTSW |
4 |
113,042,011 (GRCm39) |
splice site |
probably benign |
|
|
R0164:Skint6
|
UTSW |
4 |
112,848,433 (GRCm39) |
splice site |
probably benign |
|
|
R0312:Skint6
|
UTSW |
4 |
112,666,297 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0591:Skint6
|
UTSW |
4 |
112,715,366 (GRCm39) |
splice site |
probably benign |
|
|
R0762:Skint6
|
UTSW |
4 |
112,722,848 (GRCm39) |
splice site |
probably benign |
|
|
R0941:Skint6
|
UTSW |
4 |
113,095,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1023:Skint6
|
UTSW |
4 |
113,095,300 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1132:Skint6
|
UTSW |
4 |
112,755,296 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1228:Skint6
|
UTSW |
4 |
112,711,649 (GRCm39) |
missense |
probably benign |
|
|
R1338:Skint6
|
UTSW |
4 |
112,870,158 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1432:Skint6
|
UTSW |
4 |
112,726,721 (GRCm39) |
splice site |
probably benign |
|
|
R1512:Skint6
|
UTSW |
4 |
113,095,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1577:Skint6
|
UTSW |
4 |
113,005,720 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1733:Skint6
|
UTSW |
4 |
113,034,234 (GRCm39) |
splice site |
probably benign |
|
|
R1762:Skint6
|
UTSW |
4 |
113,093,678 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1891:Skint6
|
UTSW |
4 |
112,703,893 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1908:Skint6
|
UTSW |
4 |
112,749,187 (GRCm39) |
missense |
probably benign |
|
|
R2069:Skint6
|
UTSW |
4 |
113,095,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2089:Skint6
|
UTSW |
4 |
112,703,881 (GRCm39) |
missense |
probably benign |
|
|
R2091:Skint6
|
UTSW |
4 |
112,703,881 (GRCm39) |
missense |
probably benign |
|
|
R2091:Skint6
|
UTSW |
4 |
112,703,881 (GRCm39) |
missense |
probably benign |
|
|
R2144:Skint6
|
UTSW |
4 |
113,093,457 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2166:Skint6
|
UTSW |
4 |
112,711,649 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2192:Skint6
|
UTSW |
4 |
112,722,909 (GRCm39) |
nonsense |
probably null |
|
|
R2312:Skint6
|
UTSW |
4 |
113,095,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2324:Skint6
|
UTSW |
4 |
112,729,654 (GRCm39) |
splice site |
probably null |
|
|
R2342:Skint6
|
UTSW |
4 |
113,034,180 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3028:Skint6
|
UTSW |
4 |
113,093,690 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3704:Skint6
|
UTSW |
4 |
112,993,669 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3752:Skint6
|
UTSW |
4 |
112,700,096 (GRCm39) |
splice site |
probably benign |
|
|
R3760:Skint6
|
UTSW |
4 |
112,794,655 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R3827:Skint6
|
UTSW |
4 |
112,794,634 (GRCm39) |
missense |
probably benign |
|
|
R4377:Skint6
|
UTSW |
4 |
113,093,715 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4406:Skint6
|
UTSW |
4 |
113,013,683 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4611:Skint6
|
UTSW |
4 |
112,931,273 (GRCm39) |
missense |
probably benign |
|
|
R4780:Skint6
|
UTSW |
4 |
113,093,594 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4788:Skint6
|
UTSW |
4 |
113,095,533 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R4818:Skint6
|
UTSW |
4 |
112,812,589 (GRCm39) |
intron |
probably benign |
|
|
R4900:Skint6
|
UTSW |
4 |
112,924,667 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4972:Skint6
|
UTSW |
4 |
112,692,265 (GRCm39) |
missense |
probably benign |
|
|
R5008:Skint6
|
UTSW |
4 |
112,848,452 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5016:Skint6
|
UTSW |
4 |
113,028,730 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5085:Skint6
|
UTSW |
4 |
113,093,465 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5165:Skint6
|
UTSW |
4 |
112,722,865 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5221:Skint6
|
UTSW |
4 |
112,752,121 (GRCm39) |
splice site |
probably null |
|
|
R5310:Skint6
|
UTSW |
4 |
113,041,965 (GRCm39) |
nonsense |
probably null |
|
|
R5423:Skint6
|
UTSW |
4 |
112,707,937 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5436:Skint6
|
UTSW |
4 |
112,953,788 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5447:Skint6
|
UTSW |
4 |
112,963,106 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5564:Skint6
|
UTSW |
4 |
112,846,162 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5629:Skint6
|
UTSW |
4 |
112,870,176 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5936:Skint6
|
UTSW |
4 |
112,953,790 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5993:Skint6
|
UTSW |
4 |
112,666,276 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6027:Skint6
|
UTSW |
4 |
112,953,761 (GRCm39) |
splice site |
probably null |
|
|
R6174:Skint6
|
UTSW |
4 |
112,696,510 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6497:Skint6
|
UTSW |
4 |
113,093,595 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6552:Skint6
|
UTSW |
4 |
112,924,687 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6645:Skint6
|
UTSW |
4 |
112,749,235 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6810:Skint6
|
UTSW |
4 |
112,805,577 (GRCm39) |
splice site |
probably null |
|
|
R7003:Skint6
|
UTSW |
4 |
112,963,109 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7211:Skint6
|
UTSW |
4 |
113,095,566 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7269:Skint6
|
UTSW |
4 |
112,711,686 (GRCm39) |
splice site |
probably null |
|
|
R7398:Skint6
|
UTSW |
4 |
112,755,335 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7438:Skint6
|
UTSW |
4 |
113,095,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Skint6
|
UTSW |
4 |
113,034,243 (GRCm39) |
splice site |
probably null |
|
|
R7536:Skint6
|
UTSW |
4 |
112,668,744 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7613:Skint6
|
UTSW |
4 |
113,034,243 (GRCm39) |
splice site |
probably null |
|
|
R7956:Skint6
|
UTSW |
4 |
112,703,894 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8118:Skint6
|
UTSW |
4 |
113,013,691 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8118:Skint6
|
UTSW |
4 |
112,722,872 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8197:Skint6
|
UTSW |
4 |
112,752,040 (GRCm39) |
splice site |
probably null |
|
|
R8218:Skint6
|
UTSW |
4 |
112,696,471 (GRCm39) |
splice site |
probably null |
|
|
R8344:Skint6
|
UTSW |
4 |
113,093,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8518:Skint6
|
UTSW |
4 |
113,095,465 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R8776:Skint6
|
UTSW |
4 |
112,661,885 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8776-TAIL:Skint6
|
UTSW |
4 |
112,661,885 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8794:Skint6
|
UTSW |
4 |
113,049,869 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8796:Skint6
|
UTSW |
4 |
112,661,891 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8812:Skint6
|
UTSW |
4 |
112,846,149 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8866:Skint6
|
UTSW |
4 |
112,711,650 (GRCm39) |
missense |
probably benign |
|
|
R8881:Skint6
|
UTSW |
4 |
112,672,716 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8949:Skint6
|
UTSW |
4 |
112,931,296 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8967:Skint6
|
UTSW |
4 |
112,729,701 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Skint6
|
UTSW |
4 |
113,095,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9007:Skint6
|
UTSW |
4 |
113,095,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9053:Skint6
|
UTSW |
4 |
113,095,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9055:Skint6
|
UTSW |
4 |
113,095,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9144:Skint6
|
UTSW |
4 |
112,985,102 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9149:Skint6
|
UTSW |
4 |
113,034,173 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9297:Skint6
|
UTSW |
4 |
112,668,717 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9388:Skint6
|
UTSW |
4 |
113,049,838 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9407:Skint6
|
UTSW |
4 |
113,034,224 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9475:Skint6
|
UTSW |
4 |
112,664,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9515:Skint6
|
UTSW |
4 |
112,715,375 (GRCm39) |
missense |
probably benign |
|
|
R9572:Skint6
|
UTSW |
4 |
112,985,128 (GRCm39) |
missense |
probably benign |
|
|
R9689:Skint6
|
UTSW |
4 |
113,093,546 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9744:Skint6
|
UTSW |
4 |
112,666,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9785:Skint6
|
UTSW |
4 |
112,740,884 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1176:Skint6
|
UTSW |
4 |
113,095,491 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Z1176:Skint6
|
UTSW |
4 |
112,749,211 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
Z1176:Skint6
|
UTSW |
4 |
113,095,492 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Skint6
|
UTSW |
4 |
112,963,158 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Skint6
|
UTSW |
4 |
112,664,125 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATTATAAATCTTTTAAAGGGGCCACTC -3'
(R):5'- AGCTCTAGGCAACACAGCA -3'
Sequencing Primer
(F):5'- TAAAGGGGCCACTCTGAGTTC -3'
(R):5'- TCTAAAGCATGCTACTGCTAGC -3'
|
| Posted On |
2014-10-16 |
Incidental Mutation