Mutagenetix > Incidental Mutation

Incidental Mutation 'R2323:Dnah10'

244801

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

040314-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R2323 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

124802149-124911372 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 124819064 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Threonine at position 450 (M450T)

Ref Sequence

ENSEMBL: ENSMUSP00000114593 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000058440
AA Change: M450T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: M450T

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000141137
AA Change: M450T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: M450T

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.4%
20x: 95.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca2	G	T	2: 25,335,187 (GRCm39)	M2008I	probably benign	Het
Adgrv1	A	G	13: 81,743,298 (GRCm39)	S68P	probably damaging	Het
Albfm1	T	A	5: 90,732,711 (GRCm39)	Y507*	probably null	Het
Anks3	T	C	16: 4,768,634 (GRCm39)		probably null	Het
Asap2	T	C	12: 21,253,969 (GRCm39)	I160T	probably damaging	Het
Asb15	T	A	6: 24,556,600 (GRCm39)	F32I	probably benign	Het
Catip	A	T	1: 74,402,437 (GRCm39)	M103L	probably benign	Het
Cela2a	G	C	4: 141,553,390 (GRCm39)		probably benign	Het
Crebrf	T	C	17: 26,982,581 (GRCm39)		probably benign	Het
Dst	T	C	1: 34,267,518 (GRCm39)	S5165P	possibly damaging	Het
Esrp2	T	A	8: 106,860,934 (GRCm39)	D196V	probably benign	Het
Hmox2	A	T	16: 4,583,720 (GRCm39)	K263*	probably null	Het
Ints10	A	G	8: 69,271,997 (GRCm39)	H566R	probably benign	Het
Ints12	G	A	3: 132,815,126 (GRCm39)	M444I	possibly damaging	Het
Liph	A	G	16: 21,802,754 (GRCm39)	V105A	probably damaging	Het
Myo1e	T	A	9: 70,286,040 (GRCm39)	Y941*	probably null	Het
Myo7b	T	C	18: 32,104,398 (GRCm39)	E1450G	probably damaging	Het
Myt1	G	T	2: 181,448,350 (GRCm39)	A594S	probably damaging	Het
Npas3	T	A	12: 54,115,129 (GRCm39)	Y666N	probably damaging	Het
Npsr1	A	G	9: 24,211,732 (GRCm39)	K240E	probably damaging	Het
Or52h7	T	C	7: 104,213,826 (GRCm39)	F133L	probably benign	Het
Rtkn2	A	G	10: 67,837,764 (GRCm39)	I102M	probably damaging	Het
Rundc1	T	C	11: 101,316,101 (GRCm39)	F58L	probably damaging	Het
Snrpc	T	G	17: 28,066,948 (GRCm39)	M91R	unknown	Het
Tgfbr2	T	C	9: 115,939,212 (GRCm39)	K205R	possibly damaging	Het
Tmem181a	T	A	17: 6,346,061 (GRCm39)	L185H	probably damaging	Het
Tnfrsf21	C	A	17: 43,396,420 (GRCm39)	S568*	probably null	Het
Tulp1	C	T	17: 28,581,456 (GRCm39)	G239D	probably damaging	Het
Vmn1r234	T	C	17: 21,449,965 (GRCm39)	I293T	probably benign	Het
Vmn1r26	T	C	6: 57,985,842 (GRCm39)	K116E	probably damaging	Het
Vmn2r98	T	A	17: 19,286,081 (GRCm39)	I193K	probably benign	Het
Wnk4	T	A	11: 101,159,307 (GRCm39)	S575T	probably damaging	Het
Zfp558	A	T	9: 18,380,573 (GRCm39)		probably null	Het
Zscan18	T	C	7: 12,509,386 (GRCm39)		probably benign	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,905,667 (GRCm39)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,823,680 (GRCm39)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,871,405 (GRCm39)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,852,576 (GRCm39)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,854,276 (GRCm39)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,856,218 (GRCm39)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,861,010 (GRCm39)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,898,405 (GRCm39)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,809,553 (GRCm39)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,880,392 (GRCm39)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,864,529 (GRCm39)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,845,991 (GRCm39)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,832,850 (GRCm39)	missense	probably benign
IGL01767:Dnah10	APN	5	124,820,801 (GRCm39)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,842,008 (GRCm39)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,860,985 (GRCm39)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,866,876 (GRCm39)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,881,810 (GRCm39)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,896,430 (GRCm39)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,910,487 (GRCm39)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,850,131 (GRCm39)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,850,883 (GRCm39)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,870,916 (GRCm39)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,898,351 (GRCm39)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,864,395 (GRCm39)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,876,069 (GRCm39)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,850,809 (GRCm39)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,903,927 (GRCm39)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,807,150 (GRCm39)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,875,078 (GRCm39)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,878,886 (GRCm39)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,840,197 (GRCm39)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,807,226 (GRCm39)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,841,950 (GRCm39)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,825,521 (GRCm39)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,894,707 (GRCm39)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,894,761 (GRCm39)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,831,354 (GRCm39)	missense	probably benign	0.06
frosty	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,906,593 (GRCm39)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,807,164 (GRCm39)	missense	probably benign
P0019:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
P0037:Dnah10	UTSW	5	124,895,056 (GRCm39)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,852,588 (GRCm39)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,803,966 (GRCm39)	missense	probably benign
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,907,808 (GRCm39)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,840,140 (GRCm39)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,911,139 (GRCm39)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,873,433 (GRCm39)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,900,416 (GRCm39)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,832,799 (GRCm39)	missense	probably benign
R0480:Dnah10	UTSW	5	124,885,915 (GRCm39)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,889,787 (GRCm39)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,852,314 (GRCm39)	splice site	probably null
R0599:Dnah10	UTSW	5	124,878,017 (GRCm39)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,827,876 (GRCm39)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,906,641 (GRCm39)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,875,002 (GRCm39)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,837,078 (GRCm39)	splice site	probably null
R1248:Dnah10	UTSW	5	124,832,887 (GRCm39)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,830,390 (GRCm39)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,852,050 (GRCm39)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,839,285 (GRCm39)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,876,009 (GRCm39)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,820,750 (GRCm39)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1479:Dnah10	UTSW	5	124,854,953 (GRCm39)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,831,303 (GRCm39)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,838,016 (GRCm39)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,906,678 (GRCm39)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,842,626 (GRCm39)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,837,155 (GRCm39)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,850,254 (GRCm39)	splice site	probably null
R1828:Dnah10	UTSW	5	124,838,343 (GRCm39)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,881,753 (GRCm39)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,909,590 (GRCm39)	splice site	probably null
R1893:Dnah10	UTSW	5	124,831,381 (GRCm39)	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124,835,494 (GRCm39)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,878,048 (GRCm39)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,859,332 (GRCm39)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,852,267 (GRCm39)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,911,052 (GRCm39)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,906,651 (GRCm39)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,823,768 (GRCm39)	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124,873,405 (GRCm39)	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124,891,738 (GRCm39)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,852,045 (GRCm39)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,838,301 (GRCm39)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,808,530 (GRCm39)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,896,285 (GRCm39)	missense	probably damaging	0.97
R2435:Dnah10	UTSW	5	124,839,929 (GRCm39)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,852,542 (GRCm39)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,894,734 (GRCm39)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,896,476 (GRCm39)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,873,322 (GRCm39)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,824,694 (GRCm39)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,850,095 (GRCm39)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,854,990 (GRCm39)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,807,201 (GRCm39)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,809,394 (GRCm39)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,896,989 (GRCm39)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,839,933 (GRCm39)	splice site	probably null
R4651:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,852,581 (GRCm39)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,824,809 (GRCm39)	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124,896,408 (GRCm39)	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124,850,196 (GRCm39)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,894,812 (GRCm39)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,839,260 (GRCm39)	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124,909,577 (GRCm39)	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,856,322 (GRCm39)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,876,024 (GRCm39)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,864,484 (GRCm39)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,862,220 (GRCm39)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,868,851 (GRCm39)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,850,630 (GRCm39)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,820,693 (GRCm39)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,907,557 (GRCm39)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,830,232 (GRCm39)	missense	probably benign
R5587:Dnah10	UTSW	5	124,870,977 (GRCm39)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,819,090 (GRCm39)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,898,450 (GRCm39)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,824,810 (GRCm39)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,900,437 (GRCm39)	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,885,793 (GRCm39)	missense	probably benign
R6021:Dnah10	UTSW	5	124,814,048 (GRCm39)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,878,924 (GRCm39)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,896,274 (GRCm39)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,882,961 (GRCm39)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,830,238 (GRCm39)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,862,239 (GRCm39)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,847,663 (GRCm39)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,900,382 (GRCm39)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,820,743 (GRCm39)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,871,283 (GRCm39)	splice site	probably null
R6275:Dnah10	UTSW	5	124,862,248 (GRCm39)	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124,852,144 (GRCm39)	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124,906,710 (GRCm39)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,886,333 (GRCm39)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,839,846 (GRCm39)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,835,419 (GRCm39)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,907,097 (GRCm39)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,837,223 (GRCm39)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,882,869 (GRCm39)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,885,876 (GRCm39)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,854,890 (GRCm39)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,867,064 (GRCm39)	splice site	probably null
R6932:Dnah10	UTSW	5	124,898,514 (GRCm39)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,864,490 (GRCm39)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,893,206 (GRCm39)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,900,009 (GRCm39)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,900,006 (GRCm39)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,890,892 (GRCm39)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,909,662 (GRCm39)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,898,333 (GRCm39)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,824,803 (GRCm39)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,876,095 (GRCm39)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,823,608 (GRCm39)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,894,776 (GRCm39)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,854,298 (GRCm39)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,859,425 (GRCm39)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,803,949 (GRCm39)	missense	probably benign
R7999:Dnah10	UTSW	5	124,802,322 (GRCm39)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,877,949 (GRCm39)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,823,676 (GRCm39)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,905,575 (GRCm39)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,831,330 (GRCm39)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,877,946 (GRCm39)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,832,790 (GRCm39)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,905,524 (GRCm39)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,827,858 (GRCm39)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,859,410 (GRCm39)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,909,566 (GRCm39)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,850,606 (GRCm39)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,813,895 (GRCm39)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,893,164 (GRCm39)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,803,911 (GRCm39)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,891,685 (GRCm39)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,852,410 (GRCm39)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,842,614 (GRCm39)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,895,181 (GRCm39)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,866,828 (GRCm39)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,878,015 (GRCm39)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,891,006 (GRCm39)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,814,057 (GRCm39)	missense
R9001:Dnah10	UTSW	5	124,852,515 (GRCm39)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,820,783 (GRCm39)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,905,141 (GRCm39)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,839,237 (GRCm39)	missense
R9133:Dnah10	UTSW	5	124,859,423 (GRCm39)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,907,475 (GRCm39)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,871,437 (GRCm39)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,818,989 (GRCm39)	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124,813,900 (GRCm39)	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124,845,990 (GRCm39)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,871,507 (GRCm39)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,823,677 (GRCm39)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,900,508 (GRCm39)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,907,107 (GRCm39)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,852,249 (GRCm39)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,895,141 (GRCm39)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,854,971 (GRCm39)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
U24488:Dnah10	UTSW	5	124,891,044 (GRCm39)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,842,761 (GRCm39)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,852,419 (GRCm39)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,819,019 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,895,052 (GRCm39)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,824,683 (GRCm39)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- AGATTCCTGGCCTTGACACTAAG -3'
(R):5'- TTGCAGTCCTGGGGATGAAAC -3'

Sequencing Primer
(F):5'- GACACTAAGTCCCTCTTCTGTC -3'
(R):5'- AGCCTGCTCTACTGCTGAG -3'

Posted On

2014-10-30