Mutagenetix > Incidental Mutation

Incidental Mutation 'R2419:Tenm3'

249145

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Ten-m3, Odz3, 2610100B16Rik

MMRRC Submission

040381-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.598) question?

Stock #

R2419 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

48227682-48843951 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 48276658 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Asparagine at position 1438 (D1438N)

Ref Sequence

ENSEMBL: ENSMUSP00000033965 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000033965
AA Change: D1438N

PolyPhen 2 Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: D1438N

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000145344

Predicted Effect

probably benign
Transcript: ENSMUST00000190840
AA Change: D1422N

PolyPhen 2 Score 0.201 (Sensitivity: 0.92; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: D1422N

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Meta Mutation Damage Score

0.1188

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.2%
20x: 94.9%

Validation Efficiency

98% (57/58)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700022I11Rik	A	G	4: 42,974,146 (GRCm38)	T1160A	possibly damaging	Het
Abca2	G	A	2: 25,437,989 (GRCm38)	A768T	probably benign	Het
Acyp2	T	C	11: 30,632,316 (GRCm38)	Y33C	probably benign	Het
Ampd3	A	G	7: 110,768,369 (GRCm38)		probably benign	Het
Arap3	T	C	18: 37,989,944 (GRCm38)	D501G	probably damaging	Het
Arl4d	A	T	11: 101,666,888 (GRCm38)	Q80L	probably damaging	Het
Bcorl1	A	G	X: 48,370,541 (GRCm38)	T425A	probably damaging	Het
Ccdc38	T	A	10: 93,548,975 (GRCm38)	V35D	probably benign	Het
Cd6	G	A	19: 10,792,852 (GRCm38)	P492S	probably damaging	Het
Cdh20	G	A	1: 104,975,015 (GRCm38)	S477N	possibly damaging	Het
Cnmd	G	A	14: 79,638,048 (GRCm38)	P311S	probably damaging	Het
Cnot8	G	A	11: 58,115,310 (GRCm38)	G222R	probably damaging	Het
Dnah9	A	T	11: 66,095,415 (GRCm38)	L1131*	probably null	Het
Dscc1	G	A	15: 55,083,424 (GRCm38)	R302*	probably null	Het
Dusp18	T	C	11: 3,897,018 (GRCm38)	S3P	possibly damaging	Het
Eml2	A	G	7: 19,176,695 (GRCm38)		probably benign	Het
Foxb2	G	C	19: 16,872,961 (GRCm38)	A227G	probably damaging	Het
Hey1	A	G	3: 8,665,943 (GRCm38)		probably null	Het
Itk	A	G	11: 46,338,217 (GRCm38)	F379L	probably damaging	Het
Kcna2	G	A	3: 107,104,153 (GRCm38)	G17R	probably benign	Het
Kif7	C	A	7: 79,698,693 (GRCm38)	R1300L	probably benign	Het
Klkb1	A	T	8: 45,289,112 (GRCm38)	D43E	possibly damaging	Het
Leng9	A	G	7: 4,148,627 (GRCm38)	V350A	probably benign	Het
Lmbr1l	A	C	15: 98,907,537 (GRCm38)	F361C	possibly damaging	Het
Lrat	A	G	3: 82,903,685 (GRCm38)	S10P	probably damaging	Het
Lrrk2	C	A	15: 91,797,526 (GRCm38)		probably benign	Het
Mcur1	C	T	13: 43,549,537 (GRCm38)	V241M	possibly damaging	Het
Met	T	C	6: 17,535,830 (GRCm38)		probably benign	Het
Mical3	A	G	6: 120,959,923 (GRCm38)	V342A	probably benign	Het
Nup210	G	A	6: 91,017,556 (GRCm38)		probably benign	Het
Olfr1212	A	G	2: 88,959,036 (GRCm38)	N190S	probably benign	Het
Olfr1357	T	A	10: 78,612,387 (GRCm38)	I85F	probably benign	Het
Olfr340	T	A	2: 36,453,326 (GRCm38)	V247E	probably damaging	Het
Pcdhac1	T	C	18: 37,091,328 (GRCm38)	L398P	probably benign	Het
Phc3	T	C	3: 30,950,878 (GRCm38)	M189V	probably damaging	Het
Plcb1	A	G	2: 135,262,100 (GRCm38)		probably benign	Het
Plcxd3	G	T	15: 4,574,763 (GRCm38)	K284N	probably benign	Het
Plxnb2	A	G	15: 89,161,069 (GRCm38)	V1058A	possibly damaging	Het
Rbbp5	T	C	1: 132,493,826 (GRCm38)	I88T	possibly damaging	Het
Rfpl4b	T	C	10: 38,821,372 (GRCm38)	R78G	probably benign	Het
Rsf1	CG	CGACGGCGGGG	7: 97,579,908 (GRCm38)		probably benign	Het
Samt2	A	T	X: 154,575,227 (GRCm38)		probably null	Het
Sdad1	T	C	5: 92,305,818 (GRCm38)	H37R	possibly damaging	Het
Setd2	T	A	9: 110,548,997 (GRCm38)	F627I	possibly damaging	Het
Ski	A	G	4: 155,160,893 (GRCm38)	S293P	probably benign	Het
Slc27a1	A	G	8: 71,579,916 (GRCm38)	E191G	possibly damaging	Het
Snx18	T	C	13: 113,617,219 (GRCm38)	M393V	possibly damaging	Het
Tacc1	A	G	8: 25,182,813 (GRCm38)	V42A	possibly damaging	Het
Tbc1d8	A	G	1: 39,376,902 (GRCm38)	F897L	probably damaging	Het
Tmem62	G	A	2: 121,007,105 (GRCm38)	G501E	probably damaging	Het
Tmem94	A	G	11: 115,796,815 (GRCm38)	K1167E	probably damaging	Het
Trap1	A	G	16: 4,068,330 (GRCm38)	S88P	probably benign	Het
Ugt2b38	T	C	5: 87,423,732 (GRCm38)	D147G	probably damaging	Het
Vmn1r168	A	T	7: 23,541,399 (GRCm38)	N227I	probably benign	Het
Vmn1r203	T	A	13: 22,524,834 (GRCm38)	S262T	possibly damaging	Het
Vmn1r204	T	G	13: 22,556,250 (GRCm38)	L17R	probably damaging	Het
Zcchc14	T	A	8: 121,603,936 (GRCm38)	Q896L	probably damaging	Het
Zfp619	A	G	7: 39,535,883 (GRCm38)	K446E	possibly damaging	Het
Zpr1	T	C	9: 46,276,192 (GRCm38)		probably benign	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,417,060 (GRCm38)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,236,025 (GRCm38)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,279,042 (GRCm38)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,276,421 (GRCm38)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,417,132 (GRCm38)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,256,841 (GRCm38)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,236,423 (GRCm38)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,276,645 (GRCm38)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,228,802 (GRCm38)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,254,477 (GRCm38)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,236,758 (GRCm38)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,276,396 (GRCm38)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,276,576 (GRCm38)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,235,476 (GRCm38)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,236,694 (GRCm38)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,279,198 (GRCm38)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,288,016 (GRCm38)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,299,639 (GRCm38)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,298,956 (GRCm38)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,276,903 (GRCm38)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,298,878 (GRCm38)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	48,646,418 (GRCm38)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,235,523 (GRCm38)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,235,346 (GRCm38)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,235,607 (GRCm38)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,293,657 (GRCm38)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,343,345 (GRCm38)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,342,659 (GRCm38)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,341,034 (GRCm38)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,236,912 (GRCm38)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,232,105 (GRCm38)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,228,975 (GRCm38)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,287,791 (GRCm38)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,341,160 (GRCm38)	splice site	probably benign
R0573:Tenm3	UTSW	8	48,674,399 (GRCm38)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,277,710 (GRCm38)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,276,156 (GRCm38)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,236,525 (GRCm38)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,236,594 (GRCm38)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,335,742 (GRCm38)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,298,965 (GRCm38)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,228,542 (GRCm38)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,235,582 (GRCm38)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,240,396 (GRCm38)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,287,893 (GRCm38)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,276,400 (GRCm38)	missense	probably benign
R1455:Tenm3	UTSW	8	48,279,048 (GRCm38)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,235,971 (GRCm38)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,310,625 (GRCm38)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,343,316 (GRCm38)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,287,822 (GRCm38)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,395,576 (GRCm38)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,228,981 (GRCm38)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,236,421 (GRCm38)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,228,993 (GRCm38)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,279,074 (GRCm38)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,417,119 (GRCm38)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,310,634 (GRCm38)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,232,104 (GRCm38)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,417,179 (GRCm38)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	48,674,544 (GRCm38)	missense	probably damaging	0.98
R1801:Tenm3	UTSW	8	48,276,256 (GRCm38)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,276,346 (GRCm38)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,310,761 (GRCm38)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,236,313 (GRCm38)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,228,591 (GRCm38)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,228,668 (GRCm38)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,342,256 (GRCm38)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,343,349 (GRCm38)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,417,006 (GRCm38)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,395,544 (GRCm38)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	48,674,550 (GRCm38)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,342,337 (GRCm38)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,287,953 (GRCm38)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,240,270 (GRCm38)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,228,555 (GRCm38)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,277,746 (GRCm38)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,349,223 (GRCm38)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,349,404 (GRCm38)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,395,658 (GRCm38)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,293,726 (GRCm38)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,235,970 (GRCm38)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,310,621 (GRCm38)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,235,821 (GRCm38)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,276,861 (GRCm38)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,300,971 (GRCm38)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,278,961 (GRCm38)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,229,137 (GRCm38)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,235,826 (GRCm38)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,342,308 (GRCm38)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,229,198 (GRCm38)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,236,855 (GRCm38)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,287,831 (GRCm38)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,236,564 (GRCm38)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,367,377 (GRCm38)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,279,006 (GRCm38)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,236,764 (GRCm38)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,228,762 (GRCm38)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	48,646,498 (GRCm38)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	48,646,447 (GRCm38)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,228,508 (GRCm38)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,343,406 (GRCm38)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,395,573 (GRCm38)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,298,808 (GRCm38)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,254,622 (GRCm38)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,293,665 (GRCm38)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,417,059 (GRCm38)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,367,394 (GRCm38)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,276,849 (GRCm38)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,236,063 (GRCm38)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6516:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6747:Tenm3	UTSW	8	48,343,243 (GRCm38)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	48,646,256 (GRCm38)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	48,674,493 (GRCm38)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,256,837 (GRCm38)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,276,738 (GRCm38)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	48,674,416 (GRCm38)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,240,479 (GRCm38)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,240,444 (GRCm38)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	48,674,553 (GRCm38)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,292,236 (GRCm38)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,300,969 (GRCm38)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,235,935 (GRCm38)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,236,177 (GRCm38)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,236,183 (GRCm38)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,287,812 (GRCm38)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,276,600 (GRCm38)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,341,049 (GRCm38)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,335,727 (GRCm38)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	48,646,333 (GRCm38)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,236,465 (GRCm38)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,276,300 (GRCm38)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,229,111 (GRCm38)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,310,703 (GRCm38)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,367,422 (GRCm38)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,293,773 (GRCm38)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,287,848 (GRCm38)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,293,509 (GRCm38)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,229,181 (GRCm38)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,342,633 (GRCm38)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,299,645 (GRCm38)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,349,356 (GRCm38)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,342,449 (GRCm38)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,310,724 (GRCm38)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8831:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8853:Tenm3	UTSW	8	48,342,347 (GRCm38)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,236,402 (GRCm38)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,235,602 (GRCm38)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,279,060 (GRCm38)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,235,348 (GRCm38)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,276,687 (GRCm38)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,342,653 (GRCm38)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,254,633 (GRCm38)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,292,151 (GRCm38)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,335,513 (GRCm38)	missense	unknown
R9231:Tenm3	UTSW	8	48,236,196 (GRCm38)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	48,555,900 (GRCm38)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,417,080 (GRCm38)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,299,655 (GRCm38)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	48,674,524 (GRCm38)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,313,257 (GRCm38)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,235,761 (GRCm38)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,236,211 (GRCm38)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,300,814 (GRCm38)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,335,561 (GRCm38)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,287,829 (GRCm38)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,236,477 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,276,780 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- ATCTGCAATGTACAGAGTGCC -3'
(R):5'- CCATCTACGTCCTGGATAATAACG -3'

Sequencing Primer
(F):5'- CTGCAATGTACAGAGTGCCATCTG -3'
(R):5'- GATCACTGAAAACCGTCAG -3'

Posted On

2014-11-12