Incidental Mutation 'R2484:Prdm2'
| ID |
250796 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prdm2
|
| Ensembl Gene |
ENSMUSG00000057637 |
| Gene Name |
PR domain containing 2, with ZNF domain |
| Synonyms |
KMT8, LOC381568, Riz, E330024L24Rik, 4833427P12Rik, Riz1 |
| MMRRC Submission |
040408-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2484 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
142833961-142939560 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 142861776 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 505
(I505F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000105778]
|
| AlphaFold |
A2A7B5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105778
AA Change: I505F
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000101404
Gene: ENSMUSG00000057637
AA Change: I505F
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
146 |
2.79e-21 |
SMART |
|
coiled coil region
|
254 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
333 |
346 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
356 |
378 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
386 |
408 |
4.79e-3 |
SMART |
|
ZnF_C2H2
|
477 |
500 |
4.17e-3 |
SMART |
|
low complexity region
|
517 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
744 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
951 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1035 |
1080 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1126 |
1148 |
3.52e-1 |
SMART |
|
ZnF_C2H2
|
1154 |
1177 |
7.55e-1 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.72e-2 |
SMART |
|
low complexity region
|
1239 |
1253 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1324 |
1344 |
5.12e1 |
SMART |
|
low complexity region
|
1406 |
1423 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1446 |
1466 |
1.86e1 |
SMART |
|
low complexity region
|
1475 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1551 |
1568 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197026
|
| Meta Mutation Damage Score |
0.1280 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.5%
- 20x: 95.7%
|
| Validation Efficiency |
97% (72/74) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
PHENOTYPE: Homozygous null mice have shortened life spans, becoming moribund due to increased incidence of tumors. Mice had a broad spectrum of unusual tumors in multiple organs, with a high incidence of diffuse large B cell lymphomas. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
G |
A |
2: 68,541,819 (GRCm39) |
D46N |
possibly damaging |
Het |
| A830018L16Rik |
G |
T |
1: 11,666,526 (GRCm39) |
A278S |
probably damaging |
Het |
| Acsbg3 |
A |
G |
17: 57,189,641 (GRCm39) |
N252S |
probably benign |
Het |
| Adarb2 |
A |
T |
13: 8,619,810 (GRCm39) |
K99* |
probably null |
Het |
| Arsi |
G |
A |
18: 61,049,723 (GRCm39) |
G202E |
probably benign |
Het |
| Atxn1l |
A |
G |
8: 110,458,883 (GRCm39) |
S460P |
probably damaging |
Het |
| Bicra |
T |
A |
7: 15,722,605 (GRCm39) |
N304I |
possibly damaging |
Het |
| Capn10 |
A |
T |
1: 92,872,565 (GRCm39) |
D470V |
probably damaging |
Het |
| Chchd3 |
A |
G |
6: 32,780,950 (GRCm39) |
Y184H |
possibly damaging |
Het |
| Col6a6 |
T |
C |
9: 105,658,003 (GRCm39) |
I736M |
probably damaging |
Het |
| Dhx36 |
T |
A |
3: 62,380,236 (GRCm39) |
N820I |
probably damaging |
Het |
| Drd4 |
C |
T |
7: 140,874,649 (GRCm39) |
P347S |
probably benign |
Het |
| Ephx1 |
A |
T |
1: 180,817,537 (GRCm39) |
V378D |
probably damaging |
Het |
| Extl3 |
A |
T |
14: 65,313,184 (GRCm39) |
V666E |
probably damaging |
Het |
| Fam20c |
G |
C |
5: 138,794,872 (GRCm39) |
R500S |
probably benign |
Het |
| Glod4 |
A |
T |
11: 76,130,344 (GRCm39) |
D42E |
probably damaging |
Het |
| Golga2 |
T |
C |
2: 32,194,782 (GRCm39) |
I643T |
probably benign |
Het |
| Hnf1b |
A |
T |
11: 83,752,661 (GRCm39) |
T73S |
probably benign |
Het |
| Hydin |
A |
G |
8: 111,239,747 (GRCm39) |
Y2009C |
possibly damaging |
Het |
| Ido2 |
A |
G |
8: 25,023,831 (GRCm39) |
C336R |
probably damaging |
Het |
| Ifngr1 |
T |
C |
10: 19,477,163 (GRCm39) |
V108A |
probably damaging |
Het |
| Igbp1b |
A |
T |
6: 138,634,492 (GRCm39) |
N317K |
probably benign |
Het |
| Ints14 |
A |
G |
9: 64,893,366 (GRCm39) |
S511G |
probably benign |
Het |
| Itpr1 |
T |
C |
6: 108,346,071 (GRCm39) |
S125P |
probably damaging |
Het |
| Jag1 |
T |
C |
2: 136,926,620 (GRCm39) |
T975A |
possibly damaging |
Het |
| Klra17 |
A |
G |
6: 129,845,720 (GRCm39) |
W165R |
probably damaging |
Het |
| Leo1 |
T |
A |
9: 75,352,755 (GRCm39) |
N99K |
possibly damaging |
Het |
| Lonp1 |
C |
A |
17: 56,921,659 (GRCm39) |
G883C |
probably damaging |
Het |
| Lpin1 |
C |
A |
12: 16,597,500 (GRCm39) |
G682W |
probably damaging |
Het |
| Macf1 |
A |
C |
4: 123,367,465 (GRCm39) |
L2432R |
probably damaging |
Het |
| Med12l |
T |
G |
3: 59,205,259 (GRCm39) |
I2075M |
probably benign |
Het |
| Mroh6 |
A |
G |
15: 75,756,177 (GRCm39) |
S660P |
probably benign |
Het |
| Myh6 |
G |
T |
14: 55,198,699 (GRCm39) |
Y309* |
probably null |
Het |
| Myof |
C |
T |
19: 37,892,291 (GRCm39) |
R1154H |
probably benign |
Het |
| Myrip |
G |
A |
9: 120,253,685 (GRCm39) |
E253K |
probably benign |
Het |
| Ndst3 |
T |
C |
3: 123,346,186 (GRCm39) |
D281G |
possibly damaging |
Het |
| Nipbl |
T |
C |
15: 8,353,182 (GRCm39) |
K1788R |
probably damaging |
Het |
| Nol12 |
A |
G |
15: 78,824,717 (GRCm39) |
|
probably benign |
Het |
| Nptn |
A |
G |
9: 58,550,956 (GRCm39) |
T212A |
possibly damaging |
Het |
| Nptx2 |
C |
T |
5: 144,493,155 (GRCm39) |
A414V |
probably damaging |
Het |
| Nub1 |
A |
G |
5: 24,913,700 (GRCm39) |
D503G |
possibly damaging |
Het |
| Obscn |
T |
A |
11: 58,898,366 (GRCm39) |
|
probably benign |
Het |
| Or4a80 |
A |
G |
2: 89,582,578 (GRCm39) |
I198T |
probably benign |
Het |
| Or51q1 |
A |
G |
7: 103,628,545 (GRCm39) |
T49A |
probably benign |
Het |
| Or5b97 |
C |
T |
19: 12,879,005 (GRCm39) |
M46I |
probably benign |
Het |
| Pcnx2 |
T |
C |
8: 126,617,859 (GRCm39) |
E132G |
probably damaging |
Het |
| Pkdcc |
A |
G |
17: 83,529,667 (GRCm39) |
|
probably benign |
Het |
| Psmc3 |
C |
G |
2: 90,886,346 (GRCm39) |
Q169E |
probably damaging |
Het |
| Ptger4 |
A |
T |
15: 5,264,654 (GRCm39) |
I334N |
probably benign |
Het |
| Ptrh1 |
T |
C |
2: 32,667,183 (GRCm39) |
M161T |
probably benign |
Het |
| Rapgef6 |
T |
A |
11: 54,533,582 (GRCm39) |
V482D |
possibly damaging |
Het |
| Rdh16f2 |
T |
C |
10: 127,710,946 (GRCm39) |
S188P |
probably damaging |
Het |
| Rrh |
T |
C |
3: 129,616,040 (GRCm39) |
Y31C |
probably damaging |
Het |
| Selp |
G |
T |
1: 163,971,523 (GRCm39) |
W659L |
probably benign |
Het |
| Selp |
G |
T |
1: 163,971,524 (GRCm39) |
W659C |
probably damaging |
Het |
| Shh |
A |
G |
5: 28,671,740 (GRCm39) |
C8R |
probably benign |
Het |
| Spdye4b |
C |
A |
5: 143,187,848 (GRCm39) |
S167R |
possibly damaging |
Het |
| Strip1 |
T |
C |
3: 107,535,537 (GRCm39) |
Y62C |
possibly damaging |
Het |
| Sucla2 |
A |
T |
14: 73,819,149 (GRCm39) |
I232F |
probably benign |
Het |
| Sugp1 |
A |
G |
8: 70,522,174 (GRCm39) |
D437G |
possibly damaging |
Het |
| Taf1a |
A |
G |
1: 183,177,422 (GRCm39) |
|
probably benign |
Het |
| Tbc1d20 |
T |
A |
2: 152,153,283 (GRCm39) |
M271K |
probably damaging |
Het |
| Tecpr2 |
T |
C |
12: 110,899,752 (GRCm39) |
S707P |
probably benign |
Het |
| Tert |
G |
A |
13: 73,796,104 (GRCm39) |
R1017H |
probably benign |
Het |
| Tox |
C |
G |
4: 6,688,886 (GRCm39) |
V493L |
probably damaging |
Het |
| Tpo |
C |
T |
12: 30,153,968 (GRCm39) |
A246T |
probably benign |
Het |
| Traf7 |
A |
T |
17: 24,730,613 (GRCm39) |
V358D |
probably damaging |
Het |
| Trim56 |
C |
T |
5: 137,141,528 (GRCm39) |
V663M |
possibly damaging |
Het |
| Unc80 |
C |
T |
1: 66,560,740 (GRCm39) |
H823Y |
possibly damaging |
Het |
| Usf3 |
C |
T |
16: 44,041,045 (GRCm39) |
H1842Y |
probably damaging |
Het |
| Uvrag |
T |
C |
7: 98,537,668 (GRCm39) |
E509G |
probably benign |
Het |
| Vmn2r5 |
T |
C |
3: 64,411,392 (GRCm39) |
D305G |
possibly damaging |
Het |
| Vmn2r52 |
T |
C |
7: 9,903,058 (GRCm39) |
R457G |
probably damaging |
Het |
| Vti1a |
A |
C |
19: 55,369,411 (GRCm39) |
N101T |
possibly damaging |
Het |
| Zfp236 |
A |
G |
18: 82,686,762 (GRCm39) |
F259L |
probably benign |
Het |
|
| Other mutations in Prdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00530:Prdm2
|
APN |
4 |
142,860,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00843:Prdm2
|
APN |
4 |
142,860,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01419:Prdm2
|
APN |
4 |
142,860,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01662:Prdm2
|
APN |
4 |
142,860,138 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01892:Prdm2
|
APN |
4 |
142,860,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Prdm2
|
APN |
4 |
142,859,997 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02208:Prdm2
|
APN |
4 |
142,862,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02260:Prdm2
|
APN |
4 |
142,861,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Prdm2
|
APN |
4 |
142,861,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Prdm2
|
APN |
4 |
142,858,542 (GRCm39) |
missense |
probably benign |
|
|
IGL02972:Prdm2
|
APN |
4 |
142,858,736 (GRCm39) |
missense |
probably benign |
|
|
IGL03038:Prdm2
|
APN |
4 |
142,860,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Prdm2
|
APN |
4 |
142,861,658 (GRCm39) |
missense |
probably benign |
0.07 |
|
G1patch:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
PIT4677001:Prdm2
|
UTSW |
4 |
142,861,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0088:Prdm2
|
UTSW |
4 |
142,861,524 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0153:Prdm2
|
UTSW |
4 |
142,860,338 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0320:Prdm2
|
UTSW |
4 |
142,905,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0384:Prdm2
|
UTSW |
4 |
142,862,258 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0400:Prdm2
|
UTSW |
4 |
142,838,240 (GRCm39) |
missense |
probably benign |
|
|
R0658:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0850:Prdm2
|
UTSW |
4 |
142,858,773 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1118:Prdm2
|
UTSW |
4 |
142,858,953 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1355:Prdm2
|
UTSW |
4 |
142,858,533 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1519:Prdm2
|
UTSW |
4 |
142,862,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Prdm2
|
UTSW |
4 |
142,861,032 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1987:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2006:Prdm2
|
UTSW |
4 |
142,858,447 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2008:Prdm2
|
UTSW |
4 |
142,861,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Prdm2
|
UTSW |
4 |
142,859,334 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R2112:Prdm2
|
UTSW |
4 |
142,858,506 (GRCm39) |
missense |
probably benign |
|
|
R2221:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2223:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2426:Prdm2
|
UTSW |
4 |
142,838,320 (GRCm39) |
nonsense |
probably null |
|
|
R2430:Prdm2
|
UTSW |
4 |
142,859,733 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3735:Prdm2
|
UTSW |
4 |
142,860,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Prdm2
|
UTSW |
4 |
142,858,385 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4209:Prdm2
|
UTSW |
4 |
142,861,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4411:Prdm2
|
UTSW |
4 |
142,860,240 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4647:Prdm2
|
UTSW |
4 |
142,859,525 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4898:Prdm2
|
UTSW |
4 |
142,860,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Prdm2
|
UTSW |
4 |
142,905,937 (GRCm39) |
nonsense |
probably null |
|
|
R5181:Prdm2
|
UTSW |
4 |
142,861,536 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5513:Prdm2
|
UTSW |
4 |
142,862,463 (GRCm39) |
small deletion |
probably benign |
|
|
R5539:Prdm2
|
UTSW |
4 |
142,859,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5563:Prdm2
|
UTSW |
4 |
142,861,200 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5618:Prdm2
|
UTSW |
4 |
142,860,107 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5900:Prdm2
|
UTSW |
4 |
142,861,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5990:Prdm2
|
UTSW |
4 |
142,896,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6148:Prdm2
|
UTSW |
4 |
142,859,477 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6166:Prdm2
|
UTSW |
4 |
142,861,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6223:Prdm2
|
UTSW |
4 |
142,868,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6530:Prdm2
|
UTSW |
4 |
142,860,617 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6631:Prdm2
|
UTSW |
4 |
142,861,454 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6725:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6847:Prdm2
|
UTSW |
4 |
142,859,520 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7193:Prdm2
|
UTSW |
4 |
142,907,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Prdm2
|
UTSW |
4 |
142,862,391 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7292:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7417:Prdm2
|
UTSW |
4 |
142,905,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7748:Prdm2
|
UTSW |
4 |
142,862,459 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7885:Prdm2
|
UTSW |
4 |
142,861,140 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7936:Prdm2
|
UTSW |
4 |
142,862,434 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7976:Prdm2
|
UTSW |
4 |
142,859,812 (GRCm39) |
nonsense |
probably null |
|
|
R8124:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Prdm2
|
UTSW |
4 |
142,859,303 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8156:Prdm2
|
UTSW |
4 |
142,861,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8178:Prdm2
|
UTSW |
4 |
142,859,018 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8235:Prdm2
|
UTSW |
4 |
142,859,037 (GRCm39) |
nonsense |
probably null |
|
|
R8404:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8498:Prdm2
|
UTSW |
4 |
142,907,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8502:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8688:Prdm2
|
UTSW |
4 |
142,838,310 (GRCm39) |
missense |
probably benign |
|
|
R8732:Prdm2
|
UTSW |
4 |
142,862,580 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Prdm2
|
UTSW |
4 |
142,860,017 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8874:Prdm2
|
UTSW |
4 |
142,859,785 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8887:Prdm2
|
UTSW |
4 |
142,860,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Prdm2
|
UTSW |
4 |
142,858,449 (GRCm39) |
nonsense |
probably null |
|
|
R9139:Prdm2
|
UTSW |
4 |
142,858,752 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9165:Prdm2
|
UTSW |
4 |
142,858,674 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9342:Prdm2
|
UTSW |
4 |
142,861,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9518:Prdm2
|
UTSW |
4 |
142,860,579 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9546:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9680:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9730:Prdm2
|
UTSW |
4 |
142,858,659 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
X0017:Prdm2
|
UTSW |
4 |
142,861,277 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGTTGTTGGTCTGAATCTTACCATC -3'
(R):5'- TGAGTCGAGTCCACCTCAAC -3'
Sequencing Primer
(F):5'- CTCTGTGCTTGGTACATAGA -3'
(R):5'- CCTCAACTTGGGCAAGACTGTTTG -3'
|
| Posted On |
2014-12-04 |
Incidental Mutation