Incidental Mutation 'R2484:Zfp236'
| ID |
250899 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp236
|
| Ensembl Gene |
ENSMUSG00000041258 |
| Gene Name |
zinc finger protein 236 |
| Synonyms |
LOC240456 |
| MMRRC Submission |
040408-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R2484 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
82611718-82711008 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 82686762 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 259
(F259L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138179
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000171071]
[ENSMUST00000182122]
[ENSMUST00000183048]
|
| AlphaFold |
S4R299 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171071
AA Change: F259L
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000130004
Gene: ENSMUSG00000041258
AA Change: F259L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
low complexity region
|
290 |
309 |
N/A |
INTRINSIC |
|
low complexity region
|
403 |
426 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
436 |
458 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
464 |
486 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
492 |
514 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
520 |
542 |
1.18e-2 |
SMART |
|
low complexity region
|
592 |
605 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
611 |
633 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
639 |
661 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
667 |
689 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
695 |
717 |
7.37e-4 |
SMART |
|
low complexity region
|
720 |
733 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
922 |
944 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
950 |
972 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
978 |
1000 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1006 |
1028 |
2.75e-3 |
SMART |
|
low complexity region
|
1030 |
1039 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1122 |
1144 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1150 |
1172 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1178 |
1200 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1206 |
1228 |
5.42e-2 |
SMART |
|
low complexity region
|
1243 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1462 |
1477 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1612 |
1635 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1641 |
1663 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1677 |
1699 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1705 |
1727 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1733 |
1756 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182122
AA Change: F259L
PolyPhen 2
Score 0.025 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000138557
Gene: ENSMUSG00000041258
AA Change: F259L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
474 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
484 |
506 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
512 |
534 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
540 |
562 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
568 |
590 |
1.18e-2 |
SMART |
|
low complexity region
|
640 |
653 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
659 |
681 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
687 |
709 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
715 |
737 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
743 |
765 |
7.37e-4 |
SMART |
|
low complexity region
|
768 |
781 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
970 |
992 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
998 |
1020 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
1026 |
1048 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1054 |
1076 |
2.75e-3 |
SMART |
|
low complexity region
|
1078 |
1087 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1170 |
1192 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1198 |
1220 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1226 |
1248 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1254 |
1276 |
5.42e-2 |
SMART |
|
low complexity region
|
1291 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1525 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1660 |
1683 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1689 |
1711 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1725 |
1747 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1753 |
1775 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1781 |
1804 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183048
AA Change: F259L
PolyPhen 2
Score 0.052 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000138179
Gene: ENSMUSG00000041258
AA Change: F259L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
467 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0690 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.5%
- 20x: 95.7%
|
| Validation Efficiency |
97% (72/74) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
G |
A |
2: 68,541,819 (GRCm39) |
D46N |
possibly damaging |
Het |
| A830018L16Rik |
G |
T |
1: 11,666,526 (GRCm39) |
A278S |
probably damaging |
Het |
| Acsbg3 |
A |
G |
17: 57,189,641 (GRCm39) |
N252S |
probably benign |
Het |
| Adarb2 |
A |
T |
13: 8,619,810 (GRCm39) |
K99* |
probably null |
Het |
| Arsi |
G |
A |
18: 61,049,723 (GRCm39) |
G202E |
probably benign |
Het |
| Atxn1l |
A |
G |
8: 110,458,883 (GRCm39) |
S460P |
probably damaging |
Het |
| Bicra |
T |
A |
7: 15,722,605 (GRCm39) |
N304I |
possibly damaging |
Het |
| Capn10 |
A |
T |
1: 92,872,565 (GRCm39) |
D470V |
probably damaging |
Het |
| Chchd3 |
A |
G |
6: 32,780,950 (GRCm39) |
Y184H |
possibly damaging |
Het |
| Col6a6 |
T |
C |
9: 105,658,003 (GRCm39) |
I736M |
probably damaging |
Het |
| Dhx36 |
T |
A |
3: 62,380,236 (GRCm39) |
N820I |
probably damaging |
Het |
| Drd4 |
C |
T |
7: 140,874,649 (GRCm39) |
P347S |
probably benign |
Het |
| Ephx1 |
A |
T |
1: 180,817,537 (GRCm39) |
V378D |
probably damaging |
Het |
| Extl3 |
A |
T |
14: 65,313,184 (GRCm39) |
V666E |
probably damaging |
Het |
| Fam20c |
G |
C |
5: 138,794,872 (GRCm39) |
R500S |
probably benign |
Het |
| Glod4 |
A |
T |
11: 76,130,344 (GRCm39) |
D42E |
probably damaging |
Het |
| Golga2 |
T |
C |
2: 32,194,782 (GRCm39) |
I643T |
probably benign |
Het |
| Hnf1b |
A |
T |
11: 83,752,661 (GRCm39) |
T73S |
probably benign |
Het |
| Hydin |
A |
G |
8: 111,239,747 (GRCm39) |
Y2009C |
possibly damaging |
Het |
| Ido2 |
A |
G |
8: 25,023,831 (GRCm39) |
C336R |
probably damaging |
Het |
| Ifngr1 |
T |
C |
10: 19,477,163 (GRCm39) |
V108A |
probably damaging |
Het |
| Igbp1b |
A |
T |
6: 138,634,492 (GRCm39) |
N317K |
probably benign |
Het |
| Ints14 |
A |
G |
9: 64,893,366 (GRCm39) |
S511G |
probably benign |
Het |
| Itpr1 |
T |
C |
6: 108,346,071 (GRCm39) |
S125P |
probably damaging |
Het |
| Jag1 |
T |
C |
2: 136,926,620 (GRCm39) |
T975A |
possibly damaging |
Het |
| Klra17 |
A |
G |
6: 129,845,720 (GRCm39) |
W165R |
probably damaging |
Het |
| Leo1 |
T |
A |
9: 75,352,755 (GRCm39) |
N99K |
possibly damaging |
Het |
| Lonp1 |
C |
A |
17: 56,921,659 (GRCm39) |
G883C |
probably damaging |
Het |
| Lpin1 |
C |
A |
12: 16,597,500 (GRCm39) |
G682W |
probably damaging |
Het |
| Macf1 |
A |
C |
4: 123,367,465 (GRCm39) |
L2432R |
probably damaging |
Het |
| Med12l |
T |
G |
3: 59,205,259 (GRCm39) |
I2075M |
probably benign |
Het |
| Mroh6 |
A |
G |
15: 75,756,177 (GRCm39) |
S660P |
probably benign |
Het |
| Myh6 |
G |
T |
14: 55,198,699 (GRCm39) |
Y309* |
probably null |
Het |
| Myof |
C |
T |
19: 37,892,291 (GRCm39) |
R1154H |
probably benign |
Het |
| Myrip |
G |
A |
9: 120,253,685 (GRCm39) |
E253K |
probably benign |
Het |
| Ndst3 |
T |
C |
3: 123,346,186 (GRCm39) |
D281G |
possibly damaging |
Het |
| Nipbl |
T |
C |
15: 8,353,182 (GRCm39) |
K1788R |
probably damaging |
Het |
| Nol12 |
A |
G |
15: 78,824,717 (GRCm39) |
|
probably benign |
Het |
| Nptn |
A |
G |
9: 58,550,956 (GRCm39) |
T212A |
possibly damaging |
Het |
| Nptx2 |
C |
T |
5: 144,493,155 (GRCm39) |
A414V |
probably damaging |
Het |
| Nub1 |
A |
G |
5: 24,913,700 (GRCm39) |
D503G |
possibly damaging |
Het |
| Obscn |
T |
A |
11: 58,898,366 (GRCm39) |
|
probably benign |
Het |
| Or4a80 |
A |
G |
2: 89,582,578 (GRCm39) |
I198T |
probably benign |
Het |
| Or51q1 |
A |
G |
7: 103,628,545 (GRCm39) |
T49A |
probably benign |
Het |
| Or5b97 |
C |
T |
19: 12,879,005 (GRCm39) |
M46I |
probably benign |
Het |
| Pcnx2 |
T |
C |
8: 126,617,859 (GRCm39) |
E132G |
probably damaging |
Het |
| Pkdcc |
A |
G |
17: 83,529,667 (GRCm39) |
|
probably benign |
Het |
| Prdm2 |
T |
A |
4: 142,861,776 (GRCm39) |
I505F |
probably damaging |
Het |
| Psmc3 |
C |
G |
2: 90,886,346 (GRCm39) |
Q169E |
probably damaging |
Het |
| Ptger4 |
A |
T |
15: 5,264,654 (GRCm39) |
I334N |
probably benign |
Het |
| Ptrh1 |
T |
C |
2: 32,667,183 (GRCm39) |
M161T |
probably benign |
Het |
| Rapgef6 |
T |
A |
11: 54,533,582 (GRCm39) |
V482D |
possibly damaging |
Het |
| Rdh16f2 |
T |
C |
10: 127,710,946 (GRCm39) |
S188P |
probably damaging |
Het |
| Rrh |
T |
C |
3: 129,616,040 (GRCm39) |
Y31C |
probably damaging |
Het |
| Selp |
G |
T |
1: 163,971,523 (GRCm39) |
W659L |
probably benign |
Het |
| Selp |
G |
T |
1: 163,971,524 (GRCm39) |
W659C |
probably damaging |
Het |
| Shh |
A |
G |
5: 28,671,740 (GRCm39) |
C8R |
probably benign |
Het |
| Spdye4b |
C |
A |
5: 143,187,848 (GRCm39) |
S167R |
possibly damaging |
Het |
| Strip1 |
T |
C |
3: 107,535,537 (GRCm39) |
Y62C |
possibly damaging |
Het |
| Sucla2 |
A |
T |
14: 73,819,149 (GRCm39) |
I232F |
probably benign |
Het |
| Sugp1 |
A |
G |
8: 70,522,174 (GRCm39) |
D437G |
possibly damaging |
Het |
| Taf1a |
A |
G |
1: 183,177,422 (GRCm39) |
|
probably benign |
Het |
| Tbc1d20 |
T |
A |
2: 152,153,283 (GRCm39) |
M271K |
probably damaging |
Het |
| Tecpr2 |
T |
C |
12: 110,899,752 (GRCm39) |
S707P |
probably benign |
Het |
| Tert |
G |
A |
13: 73,796,104 (GRCm39) |
R1017H |
probably benign |
Het |
| Tox |
C |
G |
4: 6,688,886 (GRCm39) |
V493L |
probably damaging |
Het |
| Tpo |
C |
T |
12: 30,153,968 (GRCm39) |
A246T |
probably benign |
Het |
| Traf7 |
A |
T |
17: 24,730,613 (GRCm39) |
V358D |
probably damaging |
Het |
| Trim56 |
C |
T |
5: 137,141,528 (GRCm39) |
V663M |
possibly damaging |
Het |
| Unc80 |
C |
T |
1: 66,560,740 (GRCm39) |
H823Y |
possibly damaging |
Het |
| Usf3 |
C |
T |
16: 44,041,045 (GRCm39) |
H1842Y |
probably damaging |
Het |
| Uvrag |
T |
C |
7: 98,537,668 (GRCm39) |
E509G |
probably benign |
Het |
| Vmn2r5 |
T |
C |
3: 64,411,392 (GRCm39) |
D305G |
possibly damaging |
Het |
| Vmn2r52 |
T |
C |
7: 9,903,058 (GRCm39) |
R457G |
probably damaging |
Het |
| Vti1a |
A |
C |
19: 55,369,411 (GRCm39) |
N101T |
possibly damaging |
Het |
|
| Other mutations in Zfp236 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Zfp236
|
APN |
18 |
82,686,815 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01760:Zfp236
|
APN |
18 |
82,639,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01923:Zfp236
|
APN |
18 |
82,700,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01934:Zfp236
|
APN |
18 |
82,651,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01949:Zfp236
|
APN |
18 |
82,642,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02063:Zfp236
|
APN |
18 |
82,676,276 (GRCm39) |
missense |
probably benign |
|
|
IGL02496:Zfp236
|
APN |
18 |
82,648,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02513:Zfp236
|
APN |
18 |
82,648,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Zfp236
|
APN |
18 |
82,676,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL02880:Zfp236
|
APN |
18 |
82,642,584 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03156:Zfp236
|
APN |
18 |
82,698,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03261:Zfp236
|
APN |
18 |
82,648,733 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0047:Zfp236
|
UTSW |
18 |
82,698,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Zfp236
|
UTSW |
18 |
82,657,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0194:Zfp236
|
UTSW |
18 |
82,675,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0207:Zfp236
|
UTSW |
18 |
82,658,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0302:Zfp236
|
UTSW |
18 |
82,676,213 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0730:Zfp236
|
UTSW |
18 |
82,658,369 (GRCm39) |
splice site |
probably benign |
|
|
R0755:Zfp236
|
UTSW |
18 |
82,638,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1202:Zfp236
|
UTSW |
18 |
82,646,291 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1449:Zfp236
|
UTSW |
18 |
82,664,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Zfp236
|
UTSW |
18 |
82,692,549 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1785:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1786:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2042:Zfp236
|
UTSW |
18 |
82,651,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2133:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2247:Zfp236
|
UTSW |
18 |
82,622,423 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3715:Zfp236
|
UTSW |
18 |
82,651,095 (GRCm39) |
splice site |
probably benign |
|
|
R4003:Zfp236
|
UTSW |
18 |
82,698,870 (GRCm39) |
nonsense |
probably null |
|
|
R4031:Zfp236
|
UTSW |
18 |
82,642,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4482:Zfp236
|
UTSW |
18 |
82,662,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4492:Zfp236
|
UTSW |
18 |
82,648,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4502:Zfp236
|
UTSW |
18 |
82,655,079 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4561:Zfp236
|
UTSW |
18 |
82,638,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp236
|
UTSW |
18 |
82,615,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Zfp236
|
UTSW |
18 |
82,627,543 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5064:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5084:Zfp236
|
UTSW |
18 |
82,627,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Zfp236
|
UTSW |
18 |
82,637,006 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5191:Zfp236
|
UTSW |
18 |
82,639,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5264:Zfp236
|
UTSW |
18 |
82,676,198 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5264:Zfp236
|
UTSW |
18 |
82,648,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5339:Zfp236
|
UTSW |
18 |
82,642,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5375:Zfp236
|
UTSW |
18 |
82,615,813 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5445:Zfp236
|
UTSW |
18 |
82,700,281 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5513:Zfp236
|
UTSW |
18 |
82,676,147 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5527:Zfp236
|
UTSW |
18 |
82,676,159 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5628:Zfp236
|
UTSW |
18 |
82,675,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5758:Zfp236
|
UTSW |
18 |
82,689,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Zfp236
|
UTSW |
18 |
82,658,276 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6137:Zfp236
|
UTSW |
18 |
82,689,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6193:Zfp236
|
UTSW |
18 |
82,622,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6198:Zfp236
|
UTSW |
18 |
82,675,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Zfp236
|
UTSW |
18 |
82,675,229 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6705:Zfp236
|
UTSW |
18 |
82,651,862 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6948:Zfp236
|
UTSW |
18 |
82,662,187 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6989:Zfp236
|
UTSW |
18 |
82,646,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7113:Zfp236
|
UTSW |
18 |
82,638,462 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7261:Zfp236
|
UTSW |
18 |
82,627,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7363:Zfp236
|
UTSW |
18 |
82,639,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7447:Zfp236
|
UTSW |
18 |
82,651,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7564:Zfp236
|
UTSW |
18 |
82,662,366 (GRCm39) |
nonsense |
probably null |
|
|
R7731:Zfp236
|
UTSW |
18 |
82,698,798 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7857:Zfp236
|
UTSW |
18 |
82,686,726 (GRCm39) |
nonsense |
probably null |
|
|
R7860:Zfp236
|
UTSW |
18 |
82,692,481 (GRCm39) |
nonsense |
probably null |
|
|
R7904:Zfp236
|
UTSW |
18 |
82,627,507 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7948:Zfp236
|
UTSW |
18 |
82,642,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp236
|
UTSW |
18 |
82,657,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Zfp236
|
UTSW |
18 |
82,648,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8435:Zfp236
|
UTSW |
18 |
82,658,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Zfp236
|
UTSW |
18 |
82,664,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8878:Zfp236
|
UTSW |
18 |
82,617,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Zfp236
|
UTSW |
18 |
82,664,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Zfp236
|
UTSW |
18 |
82,637,042 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9076:Zfp236
|
UTSW |
18 |
82,638,469 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9243:Zfp236
|
UTSW |
18 |
82,662,050 (GRCm39) |
intron |
probably benign |
|
|
R9594:Zfp236
|
UTSW |
18 |
82,664,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9642:Zfp236
|
UTSW |
18 |
82,622,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Zfp236
|
UTSW |
18 |
82,664,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Zfp236
|
UTSW |
18 |
82,637,008 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAAACAGCATGTTCCCATCAGTG -3'
(R):5'- TTGGACACCTGGCAGAGTTC -3'
Sequencing Primer
(F):5'- GGCTACTGTACATAAACTCAATCTGC -3'
(R):5'- CTCTCATTCTGAAATATTCACAGCG -3'
|
| Posted On |
2014-12-04 |
Incidental Mutation