Incidental Mutation 'R0310:Mgam'
| ID |
25134 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mgam
|
| Ensembl Gene |
ENSMUSG00000068587 |
| Gene Name |
maltase-glucoamylase |
| Synonyms |
6030407P20Rik |
| MMRRC Submission |
038520-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.237)
|
| Stock # |
R0310 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
40605765-40746057 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 40737969 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144680
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071535]
[ENSMUST00000201148]
[ENSMUST00000202779]
[ENSMUST00000202966]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071535
|
| SMART Domains |
Protein: ENSMUSP00000071466
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
12 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
47 |
59 |
N/A |
INTRINSIC |
|
PD
|
63 |
111 |
1.81e-8 |
SMART |
|
Pfam:NtCtMGAM_N
|
124 |
233 |
6.2e-36 |
PFAM |
|
Pfam:Glyco_hydro_31
|
323 |
795 |
3.4e-145 |
PFAM |
|
PD
|
924 |
977 |
4.52e-9 |
SMART |
|
Pfam:NtCtMGAM_N
|
988 |
1101 |
1.5e-30 |
PFAM |
|
Blast:ANK
|
1141 |
1171 |
1e-7 |
BLAST |
|
Pfam:Glyco_hydro_31
|
1189 |
1691 |
2e-139 |
PFAM |
|
low complexity region
|
1776 |
1791 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201148
|
| SMART Domains |
Protein: ENSMUSP00000143946
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
12 |
34 |
N/A |
INTRINSIC |
|
low complexity region
|
47 |
59 |
N/A |
INTRINSIC |
|
PD
|
63 |
111 |
1.81e-8 |
SMART |
|
Pfam:NtCtMGAM_N
|
124 |
233 |
6.2e-36 |
PFAM |
|
Pfam:Glyco_hydro_31
|
323 |
795 |
3.4e-145 |
PFAM |
|
PD
|
924 |
977 |
4.52e-9 |
SMART |
|
Pfam:NtCtMGAM_N
|
988 |
1101 |
1.5e-30 |
PFAM |
|
Blast:ANK
|
1141 |
1171 |
1e-7 |
BLAST |
|
Pfam:Glyco_hydro_31
|
1189 |
1691 |
2e-139 |
PFAM |
|
low complexity region
|
1776 |
1791 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202775
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202779
|
| SMART Domains |
Protein: ENSMUSP00000144627
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Glyco_hydro_31
|
2 |
170 |
1.4e-53 |
PFAM |
|
PD
|
297 |
350 |
1.4e-14 |
SMART |
|
Pfam:NtCtMGAM_N
|
361 |
474 |
1.5e-26 |
PFAM |
|
Blast:ANK
|
514 |
544 |
7e-8 |
BLAST |
|
Pfam:Glyco_hydro_31
|
562 |
1064 |
2.2e-137 |
PFAM |
|
low complexity region
|
1149 |
1164 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202966
|
| SMART Domains |
Protein: ENSMUSP00000144680
Gene: ENSMUSG00000068587
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
2 |
88 |
2.6e-19 |
PROSPERO |
|
PD
|
178 |
231 |
1.4e-14 |
SMART |
|
Pfam:NtCtMGAM_N
|
242 |
355 |
1.1e-26 |
PFAM |
|
Blast:ANK
|
395 |
425 |
6e-8 |
BLAST |
|
Pfam:Glyco_hydro_31
|
443 |
945 |
1.3e-137 |
PFAM |
|
| Coding Region Coverage |
- 1x: 98.6%
- 3x: 97.3%
- 10x: 93.3%
- 20x: 82.5%
|
| Validation Efficiency |
99% (113/114) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null allele display abnormalities in starch digestion and prandial glucose homeostasis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 109 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930550C14Rik |
A |
C |
9: 53,336,971 (GRCm39) |
T92P |
probably damaging |
Het |
| Abca13 |
T |
C |
11: 9,243,810 (GRCm39) |
V1891A |
probably benign |
Het |
| Abcc1 |
T |
A |
16: 14,228,791 (GRCm39) |
I346N |
probably damaging |
Het |
| Afdn |
G |
T |
17: 14,105,770 (GRCm39) |
|
probably null |
Het |
| Ahrr |
G |
A |
13: 74,431,143 (GRCm39) |
|
probably benign |
Het |
| Akap13 |
A |
G |
7: 75,264,678 (GRCm39) |
D507G |
probably damaging |
Het |
| Akap8 |
A |
T |
17: 32,535,234 (GRCm39) |
M260K |
possibly damaging |
Het |
| Akr1b8 |
T |
C |
6: 34,342,194 (GRCm39) |
V265A |
probably benign |
Het |
| Alpk3 |
C |
G |
7: 80,728,358 (GRCm39) |
P496R |
possibly damaging |
Het |
| Ankrd13b |
A |
G |
11: 77,363,571 (GRCm39) |
V249A |
possibly damaging |
Het |
| Arid4a |
T |
C |
12: 71,122,604 (GRCm39) |
V995A |
probably benign |
Het |
| Ascc3 |
G |
T |
10: 50,625,022 (GRCm39) |
V1637L |
probably benign |
Het |
| Atad2 |
G |
A |
15: 57,977,653 (GRCm39) |
A499V |
probably damaging |
Het |
| Barhl2 |
G |
T |
5: 106,605,253 (GRCm39) |
A152E |
possibly damaging |
Het |
| Bbs12 |
T |
A |
3: 37,375,194 (GRCm39) |
D547E |
probably damaging |
Het |
| Btaf1 |
A |
G |
19: 36,981,934 (GRCm39) |
M1655V |
probably damaging |
Het |
| Ccdc50 |
T |
A |
16: 27,225,408 (GRCm39) |
H40Q |
probably damaging |
Het |
| Ccr9 |
A |
T |
9: 123,603,617 (GRCm39) |
|
probably benign |
Het |
| Cdh15 |
A |
G |
8: 123,592,175 (GRCm39) |
D654G |
probably damaging |
Het |
| Cebpz |
T |
C |
17: 79,233,553 (GRCm39) |
D758G |
probably damaging |
Het |
| Cgn |
C |
T |
3: 94,672,960 (GRCm39) |
R906K |
possibly damaging |
Het |
| Chil3 |
T |
A |
3: 106,067,839 (GRCm39) |
M109L |
possibly damaging |
Het |
| Cntnap4 |
A |
T |
8: 113,569,148 (GRCm39) |
|
probably null |
Het |
| Cyp4f18 |
C |
T |
8: 72,754,856 (GRCm39) |
|
probably benign |
Het |
| Daam2 |
A |
G |
17: 49,770,952 (GRCm39) |
|
probably null |
Het |
| Ddost |
T |
A |
4: 138,037,922 (GRCm39) |
H220Q |
probably benign |
Het |
| Dennd2a |
C |
T |
6: 39,441,135 (GRCm39) |
|
probably benign |
Het |
| Depdc1b |
G |
A |
13: 108,510,375 (GRCm39) |
V296I |
possibly damaging |
Het |
| Dnaaf4 |
A |
T |
9: 72,879,618 (GRCm39) |
D386V |
probably damaging |
Het |
| Dnah5 |
A |
T |
15: 28,299,256 (GRCm39) |
R1539S |
probably benign |
Het |
| Dusp22 |
T |
C |
13: 30,889,641 (GRCm39) |
I74T |
probably damaging |
Het |
| Epc1 |
A |
G |
18: 6,440,202 (GRCm39) |
|
probably benign |
Het |
| Epha7 |
A |
G |
4: 28,961,301 (GRCm39) |
I845V |
probably benign |
Het |
| Fanci |
C |
T |
7: 79,057,165 (GRCm39) |
|
probably benign |
Het |
| Fbn1 |
T |
A |
2: 125,205,564 (GRCm39) |
E1104V |
probably damaging |
Het |
| Fbxo8 |
T |
A |
8: 57,043,132 (GRCm39) |
F205L |
probably damaging |
Het |
| Fcgbpl1 |
G |
T |
7: 27,841,699 (GRCm39) |
V545L |
probably benign |
Het |
| Fetub |
T |
C |
16: 22,748,506 (GRCm39) |
|
probably benign |
Het |
| Frs3 |
T |
C |
17: 48,014,747 (GRCm39) |
V480A |
probably benign |
Het |
| Gne |
C |
A |
4: 44,060,157 (GRCm39) |
E79* |
probably null |
Het |
| Hrc |
T |
A |
7: 44,985,921 (GRCm39) |
H357Q |
probably benign |
Het |
| Idh1 |
T |
C |
1: 65,201,079 (GRCm39) |
M291V |
probably damaging |
Het |
| Il22b |
T |
A |
10: 118,129,090 (GRCm39) |
H133L |
probably benign |
Het |
| Ino80b |
T |
C |
6: 83,101,072 (GRCm39) |
E165G |
probably damaging |
Het |
| Inppl1 |
A |
T |
7: 101,477,706 (GRCm39) |
|
probably benign |
Het |
| Ints15 |
G |
T |
5: 143,293,643 (GRCm39) |
T278K |
probably benign |
Het |
| Ip6k2 |
T |
C |
9: 108,676,432 (GRCm39) |
|
probably benign |
Het |
| Itga11 |
A |
T |
9: 62,667,628 (GRCm39) |
I654F |
probably damaging |
Het |
| Jag2 |
G |
T |
12: 112,876,997 (GRCm39) |
|
probably benign |
Het |
| Katna1 |
G |
T |
10: 7,619,513 (GRCm39) |
|
probably benign |
Het |
| Kcnh4 |
G |
T |
11: 100,636,995 (GRCm39) |
S707Y |
probably benign |
Het |
| Kcnn2 |
T |
G |
18: 45,693,585 (GRCm39) |
L387R |
probably damaging |
Het |
| Khnyn |
A |
G |
14: 56,125,425 (GRCm39) |
T503A |
probably damaging |
Het |
| Lama5 |
G |
T |
2: 179,823,359 (GRCm39) |
|
probably benign |
Het |
| Lmbr1l |
A |
T |
15: 98,806,654 (GRCm39) |
|
probably benign |
Het |
| Mast4 |
A |
T |
13: 102,890,669 (GRCm39) |
S870T |
possibly damaging |
Het |
| Med1 |
A |
G |
11: 98,058,400 (GRCm39) |
Y266H |
probably benign |
Het |
| Med13 |
A |
T |
11: 86,236,829 (GRCm39) |
N109K |
probably benign |
Het |
| Mmp8 |
A |
G |
9: 7,561,455 (GRCm39) |
Q153R |
probably benign |
Het |
| Mpeg1 |
C |
A |
19: 12,439,055 (GRCm39) |
T171N |
probably benign |
Het |
| Mtus2 |
T |
C |
5: 148,043,829 (GRCm39) |
S806P |
probably benign |
Het |
| Naip2 |
T |
A |
13: 100,285,350 (GRCm39) |
E1226V |
probably damaging |
Het |
| Naip6 |
A |
G |
13: 100,444,721 (GRCm39) |
F246L |
possibly damaging |
Het |
| Nav3 |
T |
C |
10: 109,602,989 (GRCm39) |
I1187V |
possibly damaging |
Het |
| Nbeal1 |
T |
C |
1: 60,344,529 (GRCm39) |
|
probably benign |
Het |
| Nbeal2 |
C |
A |
9: 110,467,231 (GRCm39) |
V653L |
probably damaging |
Het |
| Ndufa9 |
G |
T |
6: 126,804,495 (GRCm39) |
|
probably benign |
Het |
| Nlrp5 |
G |
T |
7: 23,129,582 (GRCm39) |
C883F |
probably damaging |
Het |
| Nr0b2 |
C |
A |
4: 133,283,303 (GRCm39) |
|
probably null |
Het |
| Or1m1 |
T |
A |
9: 18,666,629 (GRCm39) |
M101L |
possibly damaging |
Het |
| Or6c209 |
T |
A |
10: 129,483,600 (GRCm39) |
V201E |
probably damaging |
Het |
| Or6c69c |
G |
A |
10: 129,910,692 (GRCm39) |
V138I |
probably benign |
Het |
| Or8b101 |
T |
A |
9: 38,020,782 (GRCm39) |
S267T |
possibly damaging |
Het |
| Pkhd1 |
A |
T |
1: 20,620,046 (GRCm39) |
|
probably null |
Het |
| Pkhd1l1 |
A |
G |
15: 44,386,134 (GRCm39) |
|
probably benign |
Het |
| Ppm1l |
A |
G |
3: 69,456,794 (GRCm39) |
K237R |
probably benign |
Het |
| Ppp1r18 |
T |
C |
17: 36,184,603 (GRCm39) |
|
probably benign |
Het |
| Ptpn3 |
A |
T |
4: 57,204,958 (GRCm39) |
D734E |
probably benign |
Het |
| Pxdn |
T |
C |
12: 30,065,528 (GRCm39) |
C1283R |
probably damaging |
Het |
| Rbm12 |
A |
G |
2: 155,937,644 (GRCm39) |
|
probably benign |
Het |
| Rttn |
A |
T |
18: 89,027,584 (GRCm39) |
|
probably benign |
Het |
| Sgsm1 |
G |
T |
5: 113,411,571 (GRCm39) |
H431Q |
probably benign |
Het |
| Siah3 |
A |
G |
14: 75,763,367 (GRCm39) |
N206S |
possibly damaging |
Het |
| Slc22a15 |
G |
T |
3: 101,767,827 (GRCm39) |
D521E |
probably benign |
Het |
| Sprr2k |
A |
T |
3: 92,340,770 (GRCm39) |
|
probably benign |
Het |
| Stab2 |
G |
A |
10: 86,803,477 (GRCm39) |
|
probably benign |
Het |
| Sval3 |
T |
A |
6: 41,945,120 (GRCm39) |
L16Q |
probably damaging |
Het |
| Sycp2 |
C |
G |
2: 178,023,648 (GRCm39) |
S456T |
probably benign |
Het |
| Tk1 |
T |
C |
11: 117,707,921 (GRCm39) |
|
probably benign |
Het |
| Tlk2 |
C |
A |
11: 105,145,799 (GRCm39) |
A335E |
probably benign |
Het |
| Tmtc1 |
T |
C |
6: 148,151,079 (GRCm39) |
K659E |
probably benign |
Het |
| Tnk2 |
C |
T |
16: 32,499,408 (GRCm39) |
P907L |
probably benign |
Het |
| Trim14 |
C |
A |
4: 46,522,043 (GRCm39) |
K211N |
probably damaging |
Het |
| Trim15 |
A |
C |
17: 37,177,878 (GRCm39) |
L39R |
probably damaging |
Het |
| Tspan15 |
T |
A |
10: 62,023,872 (GRCm39) |
T269S |
probably benign |
Het |
| Ttc7 |
T |
A |
17: 87,669,292 (GRCm39) |
D646E |
probably benign |
Het |
| Ttll6 |
A |
T |
11: 96,038,382 (GRCm39) |
Q410L |
probably benign |
Het |
| Unc79 |
A |
G |
12: 103,027,666 (GRCm39) |
Q419R |
probably damaging |
Het |
| Vcam1 |
A |
T |
3: 115,908,065 (GRCm39) |
Y666N |
possibly damaging |
Het |
| Vmn1r10 |
A |
T |
6: 57,090,486 (GRCm39) |
Y26F |
probably damaging |
Het |
| Vmn1r80 |
A |
G |
7: 11,927,775 (GRCm39) |
N295S |
probably benign |
Het |
| Vmn2r114 |
A |
T |
17: 23,509,917 (GRCm39) |
H854Q |
probably benign |
Het |
| Vmn2r2 |
A |
T |
3: 64,042,039 (GRCm39) |
D225E |
probably damaging |
Het |
| Vmn2r4 |
A |
T |
3: 64,296,855 (GRCm39) |
Y643* |
probably null |
Het |
| Vmn2r52 |
T |
A |
7: 9,893,393 (GRCm39) |
Y582F |
probably damaging |
Het |
| Vmn2r60 |
G |
T |
7: 41,844,564 (GRCm39) |
L642F |
possibly damaging |
Het |
| Zbtb20 |
T |
C |
16: 43,430,109 (GRCm39) |
S207P |
probably damaging |
Het |
| Zic2 |
CCCACCACCACCATCACCACCACCACC |
CCCACCATCACCACCACCACC |
14: 122,713,776 (GRCm39) |
|
probably benign |
Het |
| Zkscan7 |
G |
T |
9: 122,717,958 (GRCm39) |
E118* |
probably null |
Het |
|
| Other mutations in Mgam |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01024:Mgam
|
APN |
6 |
40,619,944 (GRCm39) |
missense |
probably benign |
|
|
IGL01065:Mgam
|
APN |
6 |
40,639,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01402:Mgam
|
APN |
6 |
40,621,879 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01404:Mgam
|
APN |
6 |
40,621,879 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01413:Mgam
|
APN |
6 |
40,638,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01546:Mgam
|
APN |
6 |
40,631,627 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01596:Mgam
|
APN |
6 |
40,635,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02133:Mgam
|
APN |
6 |
40,620,010 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02734:Mgam
|
APN |
6 |
40,639,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB002:Mgam
|
UTSW |
6 |
40,735,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
BB012:Mgam
|
UTSW |
6 |
40,735,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0012:Mgam
|
UTSW |
6 |
40,742,190 (GRCm39) |
splice site |
probably null |
|
|
R0116:Mgam
|
UTSW |
6 |
40,635,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0452:Mgam
|
UTSW |
6 |
40,736,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0497:Mgam
|
UTSW |
6 |
40,641,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0699:Mgam
|
UTSW |
6 |
40,619,953 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0738:Mgam
|
UTSW |
6 |
40,731,869 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1033:Mgam
|
UTSW |
6 |
40,657,558 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1403:Mgam
|
UTSW |
6 |
40,643,815 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1403:Mgam
|
UTSW |
6 |
40,643,815 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1430:Mgam
|
UTSW |
6 |
40,733,305 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1432:Mgam
|
UTSW |
6 |
40,733,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1443:Mgam
|
UTSW |
6 |
40,736,714 (GRCm39) |
nonsense |
probably null |
|
|
R1470:Mgam
|
UTSW |
6 |
40,736,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Mgam
|
UTSW |
6 |
40,736,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1519:Mgam
|
UTSW |
6 |
40,638,617 (GRCm39) |
missense |
probably benign |
0.45 |
|
R1654:Mgam
|
UTSW |
6 |
40,734,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1667:Mgam
|
UTSW |
6 |
40,653,978 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1730:Mgam
|
UTSW |
6 |
40,641,794 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1781:Mgam
|
UTSW |
6 |
40,646,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1783:Mgam
|
UTSW |
6 |
40,641,794 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1829:Mgam
|
UTSW |
6 |
40,643,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1833:Mgam
|
UTSW |
6 |
40,631,652 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1872:Mgam
|
UTSW |
6 |
40,638,234 (GRCm39) |
nonsense |
probably null |
|
|
R1912:Mgam
|
UTSW |
6 |
40,741,119 (GRCm39) |
nonsense |
probably null |
|
|
R1977:Mgam
|
UTSW |
6 |
40,641,814 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2048:Mgam
|
UTSW |
6 |
40,633,363 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2086:Mgam
|
UTSW |
6 |
40,737,962 (GRCm39) |
splice site |
probably null |
|
|
R2138:Mgam
|
UTSW |
6 |
40,733,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2224:Mgam
|
UTSW |
6 |
40,741,208 (GRCm39) |
splice site |
probably null |
|
|
R2408:Mgam
|
UTSW |
6 |
40,663,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2508:Mgam
|
UTSW |
6 |
40,736,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2842:Mgam
|
UTSW |
6 |
40,638,279 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2847:Mgam
|
UTSW |
6 |
40,629,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R2848:Mgam
|
UTSW |
6 |
40,629,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R2965:Mgam
|
UTSW |
6 |
40,745,154 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R2966:Mgam
|
UTSW |
6 |
40,745,154 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3035:Mgam
|
UTSW |
6 |
40,640,464 (GRCm39) |
missense |
probably benign |
|
|
R3895:Mgam
|
UTSW |
6 |
40,736,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4027:Mgam
|
UTSW |
6 |
40,731,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4030:Mgam
|
UTSW |
6 |
40,731,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4302:Mgam
|
UTSW |
6 |
40,740,019 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4707:Mgam
|
UTSW |
6 |
40,691,566 (GRCm39) |
splice site |
probably null |
|
|
R4826:Mgam
|
UTSW |
6 |
40,657,582 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4898:Mgam
|
UTSW |
6 |
40,619,988 (GRCm39) |
missense |
probably benign |
|
|
R5438:Mgam
|
UTSW |
6 |
40,661,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5492:Mgam
|
UTSW |
6 |
40,733,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Mgam
|
UTSW |
6 |
40,646,738 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5839:Mgam
|
UTSW |
6 |
40,716,998 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5845:Mgam
|
UTSW |
6 |
40,652,257 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R5847:Mgam
|
UTSW |
6 |
40,660,989 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5891:Mgam
|
UTSW |
6 |
40,721,282 (GRCm39) |
missense |
probably benign |
|
|
R6158:Mgam
|
UTSW |
6 |
40,734,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6193:Mgam
|
UTSW |
6 |
40,724,854 (GRCm39) |
nonsense |
probably null |
|
|
R6423:Mgam
|
UTSW |
6 |
40,653,979 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6706:Mgam
|
UTSW |
6 |
40,721,720 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6813:Mgam
|
UTSW |
6 |
40,727,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6863:Mgam
|
UTSW |
6 |
40,705,943 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6906:Mgam
|
UTSW |
6 |
40,724,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7091:Mgam
|
UTSW |
6 |
40,745,210 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7099:Mgam
|
UTSW |
6 |
40,638,650 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7282:Mgam
|
UTSW |
6 |
40,740,045 (GRCm39) |
missense |
probably benign |
|
|
R7282:Mgam
|
UTSW |
6 |
40,633,446 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7354:Mgam
|
UTSW |
6 |
40,721,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7374:Mgam
|
UTSW |
6 |
40,734,373 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7399:Mgam
|
UTSW |
6 |
40,643,788 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7406:Mgam
|
UTSW |
6 |
40,640,459 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7446:Mgam
|
UTSW |
6 |
40,723,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7466:Mgam
|
UTSW |
6 |
40,721,723 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7525:Mgam
|
UTSW |
6 |
40,742,954 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7530:Mgam
|
UTSW |
6 |
40,686,152 (GRCm39) |
splice site |
probably null |
|
|
R7570:Mgam
|
UTSW |
6 |
40,723,367 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7669:Mgam
|
UTSW |
6 |
40,635,944 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7679:Mgam
|
UTSW |
6 |
40,619,980 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7746:Mgam
|
UTSW |
6 |
40,645,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7859:Mgam
|
UTSW |
6 |
40,717,113 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7925:Mgam
|
UTSW |
6 |
40,735,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8206:Mgam
|
UTSW |
6 |
40,657,169 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8244:Mgam
|
UTSW |
6 |
40,727,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8309:Mgam
|
UTSW |
6 |
40,722,111 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8472:Mgam
|
UTSW |
6 |
40,671,460 (GRCm39) |
splice site |
probably null |
|
|
R8758:Mgam
|
UTSW |
6 |
40,705,977 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8777:Mgam
|
UTSW |
6 |
40,632,185 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8777-TAIL:Mgam
|
UTSW |
6 |
40,632,185 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8783:Mgam
|
UTSW |
6 |
40,633,423 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8939:Mgam
|
UTSW |
6 |
40,740,137 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8968:Mgam
|
UTSW |
6 |
40,734,745 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8987:Mgam
|
UTSW |
6 |
40,706,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9055:Mgam
|
UTSW |
6 |
40,691,663 (GRCm39) |
intron |
probably benign |
|
|
R9171:Mgam
|
UTSW |
6 |
40,745,146 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9252:Mgam
|
UTSW |
6 |
40,706,577 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9258:Mgam
|
UTSW |
6 |
40,657,121 (GRCm39) |
missense |
probably benign |
|
|
R9262:Mgam
|
UTSW |
6 |
40,723,422 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9287:Mgam
|
UTSW |
6 |
40,705,905 (GRCm39) |
intron |
probably benign |
|
|
R9521:Mgam
|
UTSW |
6 |
40,722,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9589:Mgam
|
UTSW |
6 |
40,727,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9658:Mgam
|
UTSW |
6 |
40,721,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9784:Mgam
|
UTSW |
6 |
40,736,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF011:Mgam
|
UTSW |
6 |
40,734,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF020:Mgam
|
UTSW |
6 |
40,662,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF023:Mgam
|
UTSW |
6 |
40,657,642 (GRCm39) |
missense |
probably benign |
|
|
X0021:Mgam
|
UTSW |
6 |
40,635,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Mgam
|
UTSW |
6 |
40,619,994 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Mgam
|
UTSW |
6 |
40,706,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Mgam
|
UTSW |
6 |
40,654,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Mgam
|
UTSW |
6 |
40,717,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGCAAACAGTCAGTCCTCTCACC -3'
(R):5'- GCACATGGTTTCCAGGGCAGATAC -3'
Sequencing Primer
(F):5'- aacaaaaacaacaacaacaacaaac -3'
(R):5'- CCAGGGCAGATACTTAGTGTG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation