Mutagenetix > Incidental Mutation

Incidental Mutation 'R0310:Stab2'

25198

Institutional Source

Beutler Lab

Gene Symbol

Stab2

Ensembl Gene

ENSMUSG00000035459

Gene Name

stabilin 2

Synonyms

FEEL-2, STAB-2

MMRRC Submission

038520-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R0310 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

86677062-86843889 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

G to A at 86803477 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000048309 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035288]

AlphaFold

Q8R4U0

Predicted Effect

probably benign
Transcript: ENSMUST00000035288

SMART Domains

Protein: ENSMUSP00000048309
Gene: ENSMUSG00000035459

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
EGF	119	156	1.85e0	SMART
EGF	167	201	2.43e1	SMART
EGF	206	244	1.43e-1	SMART
EGF	248	284	3.82e-2	SMART
EGF	333	370	2.02e-1	SMART
FAS1	414	515	1.06e-8	SMART
FAS1	561	662	3.54e-19	SMART
EGF	746	783	6.76e-3	SMART
EGF	836	873	1.31e0	SMART
EGF	877	917	2.99e-4	SMART
EGF	921	960	3.51e-1	SMART
EGF	964	1002	1.99e0	SMART
FAS1	1038	1138	1.73e-13	SMART
FAS1	1181	1276	1.83e-12	SMART
EGF	1354	1391	6.92e0	SMART
EGF	1401	1435	1.11e1	SMART
EGF	1442	1477	3.01e0	SMART
EGF	1481	1519	1.64e-1	SMART
EGF	1523	1561	1.14e0	SMART
EGF	1565	1603	5.62e0	SMART
FAS1	1638	1734	2.23e-25	SMART
FAS1	1785	1891	6.92e-22	SMART
EGF	1966	2006	1.95e1	SMART
EGF_like	1977	2017	2.46e-1	SMART
EGF	2016	2050	1.14e0	SMART
EGF	2058	2089	1.56e1	SMART
EGF	2093	2130	1.36e1	SMART
EGF	2134	2173	2.13e0	SMART
LINK	2204	2298	2.08e-29	SMART
FAS1	2363	2455	3.19e-12	SMART
transmembrane domain	2467	2489	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000162837

Coding Region Coverage

1x: 98.6%
3x: 97.3%
10x: 93.3%
20x: 82.5%

Validation Efficiency

99% (113/114)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for knock-out alleles exhibit no gross abnormaities. Mice homozygous for one null allele display elevated serum hyaluronic acid levels and decreased metastasis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 109 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930550C14Rik	A	C	9: 53,336,971 (GRCm39)	T92P	probably damaging	Het
Abca13	T	C	11: 9,243,810 (GRCm39)	V1891A	probably benign	Het
Abcc1	T	A	16: 14,228,791 (GRCm39)	I346N	probably damaging	Het
Afdn	G	T	17: 14,105,770 (GRCm39)		probably null	Het
Ahrr	G	A	13: 74,431,143 (GRCm39)		probably benign	Het
Akap13	A	G	7: 75,264,678 (GRCm39)	D507G	probably damaging	Het
Akap8	A	T	17: 32,535,234 (GRCm39)	M260K	possibly damaging	Het
Akr1b8	T	C	6: 34,342,194 (GRCm39)	V265A	probably benign	Het
Alpk3	C	G	7: 80,728,358 (GRCm39)	P496R	possibly damaging	Het
Ankrd13b	A	G	11: 77,363,571 (GRCm39)	V249A	possibly damaging	Het
Arid4a	T	C	12: 71,122,604 (GRCm39)	V995A	probably benign	Het
Ascc3	G	T	10: 50,625,022 (GRCm39)	V1637L	probably benign	Het
Atad2	G	A	15: 57,977,653 (GRCm39)	A499V	probably damaging	Het
Barhl2	G	T	5: 106,605,253 (GRCm39)	A152E	possibly damaging	Het
Bbs12	T	A	3: 37,375,194 (GRCm39)	D547E	probably damaging	Het
Btaf1	A	G	19: 36,981,934 (GRCm39)	M1655V	probably damaging	Het
Ccdc50	T	A	16: 27,225,408 (GRCm39)	H40Q	probably damaging	Het
Ccr9	A	T	9: 123,603,617 (GRCm39)		probably benign	Het
Cdh15	A	G	8: 123,592,175 (GRCm39)	D654G	probably damaging	Het
Cebpz	T	C	17: 79,233,553 (GRCm39)	D758G	probably damaging	Het
Cgn	C	T	3: 94,672,960 (GRCm39)	R906K	possibly damaging	Het
Chil3	T	A	3: 106,067,839 (GRCm39)	M109L	possibly damaging	Het
Cntnap4	A	T	8: 113,569,148 (GRCm39)		probably null	Het
Cyp4f18	C	T	8: 72,754,856 (GRCm39)		probably benign	Het
Daam2	A	G	17: 49,770,952 (GRCm39)		probably null	Het
Ddost	T	A	4: 138,037,922 (GRCm39)	H220Q	probably benign	Het
Dennd2a	C	T	6: 39,441,135 (GRCm39)		probably benign	Het
Depdc1b	G	A	13: 108,510,375 (GRCm39)	V296I	possibly damaging	Het
Dnaaf4	A	T	9: 72,879,618 (GRCm39)	D386V	probably damaging	Het
Dnah5	A	T	15: 28,299,256 (GRCm39)	R1539S	probably benign	Het
Dusp22	T	C	13: 30,889,641 (GRCm39)	I74T	probably damaging	Het
Epc1	A	G	18: 6,440,202 (GRCm39)		probably benign	Het
Epha7	A	G	4: 28,961,301 (GRCm39)	I845V	probably benign	Het
Fanci	C	T	7: 79,057,165 (GRCm39)		probably benign	Het
Fbn1	T	A	2: 125,205,564 (GRCm39)	E1104V	probably damaging	Het
Fbxo8	T	A	8: 57,043,132 (GRCm39)	F205L	probably damaging	Het
Fcgbpl1	G	T	7: 27,841,699 (GRCm39)	V545L	probably benign	Het
Fetub	T	C	16: 22,748,506 (GRCm39)		probably benign	Het
Frs3	T	C	17: 48,014,747 (GRCm39)	V480A	probably benign	Het
Gne	C	A	4: 44,060,157 (GRCm39)	E79*	probably null	Het
Hrc	T	A	7: 44,985,921 (GRCm39)	H357Q	probably benign	Het
Idh1	T	C	1: 65,201,079 (GRCm39)	M291V	probably damaging	Het
Il22b	T	A	10: 118,129,090 (GRCm39)	H133L	probably benign	Het
Ino80b	T	C	6: 83,101,072 (GRCm39)	E165G	probably damaging	Het
Inppl1	A	T	7: 101,477,706 (GRCm39)		probably benign	Het
Ints15	G	T	5: 143,293,643 (GRCm39)	T278K	probably benign	Het
Ip6k2	T	C	9: 108,676,432 (GRCm39)		probably benign	Het
Itga11	A	T	9: 62,667,628 (GRCm39)	I654F	probably damaging	Het
Jag2	G	T	12: 112,876,997 (GRCm39)		probably benign	Het
Katna1	G	T	10: 7,619,513 (GRCm39)		probably benign	Het
Kcnh4	G	T	11: 100,636,995 (GRCm39)	S707Y	probably benign	Het
Kcnn2	T	G	18: 45,693,585 (GRCm39)	L387R	probably damaging	Het
Khnyn	A	G	14: 56,125,425 (GRCm39)	T503A	probably damaging	Het
Lama5	G	T	2: 179,823,359 (GRCm39)		probably benign	Het
Lmbr1l	A	T	15: 98,806,654 (GRCm39)		probably benign	Het
Mast4	A	T	13: 102,890,669 (GRCm39)	S870T	possibly damaging	Het
Med1	A	G	11: 98,058,400 (GRCm39)	Y266H	probably benign	Het
Med13	A	T	11: 86,236,829 (GRCm39)	N109K	probably benign	Het
Mgam	T	C	6: 40,737,969 (GRCm39)		probably benign	Het
Mmp8	A	G	9: 7,561,455 (GRCm39)	Q153R	probably benign	Het
Mpeg1	C	A	19: 12,439,055 (GRCm39)	T171N	probably benign	Het
Mtus2	T	C	5: 148,043,829 (GRCm39)	S806P	probably benign	Het
Naip2	T	A	13: 100,285,350 (GRCm39)	E1226V	probably damaging	Het
Naip6	A	G	13: 100,444,721 (GRCm39)	F246L	possibly damaging	Het
Nav3	T	C	10: 109,602,989 (GRCm39)	I1187V	possibly damaging	Het
Nbeal1	T	C	1: 60,344,529 (GRCm39)		probably benign	Het
Nbeal2	C	A	9: 110,467,231 (GRCm39)	V653L	probably damaging	Het
Ndufa9	G	T	6: 126,804,495 (GRCm39)		probably benign	Het
Nlrp5	G	T	7: 23,129,582 (GRCm39)	C883F	probably damaging	Het
Nr0b2	C	A	4: 133,283,303 (GRCm39)		probably null	Het
Or1m1	T	A	9: 18,666,629 (GRCm39)	M101L	possibly damaging	Het
Or6c209	T	A	10: 129,483,600 (GRCm39)	V201E	probably damaging	Het
Or6c69c	G	A	10: 129,910,692 (GRCm39)	V138I	probably benign	Het
Or8b101	T	A	9: 38,020,782 (GRCm39)	S267T	possibly damaging	Het
Pkhd1	A	T	1: 20,620,046 (GRCm39)		probably null	Het
Pkhd1l1	A	G	15: 44,386,134 (GRCm39)		probably benign	Het
Ppm1l	A	G	3: 69,456,794 (GRCm39)	K237R	probably benign	Het
Ppp1r18	T	C	17: 36,184,603 (GRCm39)		probably benign	Het
Ptpn3	A	T	4: 57,204,958 (GRCm39)	D734E	probably benign	Het
Pxdn	T	C	12: 30,065,528 (GRCm39)	C1283R	probably damaging	Het
Rbm12	A	G	2: 155,937,644 (GRCm39)		probably benign	Het
Rttn	A	T	18: 89,027,584 (GRCm39)		probably benign	Het
Sgsm1	G	T	5: 113,411,571 (GRCm39)	H431Q	probably benign	Het
Siah3	A	G	14: 75,763,367 (GRCm39)	N206S	possibly damaging	Het
Slc22a15	G	T	3: 101,767,827 (GRCm39)	D521E	probably benign	Het
Sprr2k	A	T	3: 92,340,770 (GRCm39)		probably benign	Het
Sval3	T	A	6: 41,945,120 (GRCm39)	L16Q	probably damaging	Het
Sycp2	C	G	2: 178,023,648 (GRCm39)	S456T	probably benign	Het
Tk1	T	C	11: 117,707,921 (GRCm39)		probably benign	Het
Tlk2	C	A	11: 105,145,799 (GRCm39)	A335E	probably benign	Het
Tmtc1	T	C	6: 148,151,079 (GRCm39)	K659E	probably benign	Het
Tnk2	C	T	16: 32,499,408 (GRCm39)	P907L	probably benign	Het
Trim14	C	A	4: 46,522,043 (GRCm39)	K211N	probably damaging	Het
Trim15	A	C	17: 37,177,878 (GRCm39)	L39R	probably damaging	Het
Tspan15	T	A	10: 62,023,872 (GRCm39)	T269S	probably benign	Het
Ttc7	T	A	17: 87,669,292 (GRCm39)	D646E	probably benign	Het
Ttll6	A	T	11: 96,038,382 (GRCm39)	Q410L	probably benign	Het
Unc79	A	G	12: 103,027,666 (GRCm39)	Q419R	probably damaging	Het
Vcam1	A	T	3: 115,908,065 (GRCm39)	Y666N	possibly damaging	Het
Vmn1r10	A	T	6: 57,090,486 (GRCm39)	Y26F	probably damaging	Het
Vmn1r80	A	G	7: 11,927,775 (GRCm39)	N295S	probably benign	Het
Vmn2r114	A	T	17: 23,509,917 (GRCm39)	H854Q	probably benign	Het
Vmn2r2	A	T	3: 64,042,039 (GRCm39)	D225E	probably damaging	Het
Vmn2r4	A	T	3: 64,296,855 (GRCm39)	Y643*	probably null	Het
Vmn2r52	T	A	7: 9,893,393 (GRCm39)	Y582F	probably damaging	Het
Vmn2r60	G	T	7: 41,844,564 (GRCm39)	L642F	possibly damaging	Het
Zbtb20	T	C	16: 43,430,109 (GRCm39)	S207P	probably damaging	Het
Zic2	CCCACCACCACCATCACCACCACCACC	CCCACCATCACCACCACCACC	14: 122,713,776 (GRCm39)		probably benign	Het
Zkscan7	G	T	9: 122,717,958 (GRCm39)	E118*	probably null	Het

Other mutations in Stab2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00091:Stab2	APN	10	86,705,070 (GRCm39)	splice site	probably null
IGL00809:Stab2	APN	10	86,684,038 (GRCm39)	splice site	probably benign
IGL00911:Stab2	APN	10	86,805,617 (GRCm39)	missense	probably damaging	1.00
IGL01347:Stab2	APN	10	86,737,567 (GRCm39)	splice site	probably null
IGL01411:Stab2	APN	10	86,815,872 (GRCm39)	splice site	probably benign
IGL01503:Stab2	APN	10	86,776,477 (GRCm39)	splice site	probably benign
IGL01599:Stab2	APN	10	86,758,759 (GRCm39)	missense	probably damaging	1.00
IGL01635:Stab2	APN	10	86,816,992 (GRCm39)	missense	probably benign	0.04
IGL01640:Stab2	APN	10	86,790,035 (GRCm39)	missense	probably benign	0.09
IGL01671:Stab2	APN	10	86,805,141 (GRCm39)	missense	possibly damaging	0.80
IGL02023:Stab2	APN	10	86,707,695 (GRCm39)	missense	possibly damaging	0.67
IGL02075:Stab2	APN	10	86,803,514 (GRCm39)	missense	possibly damaging	0.71
IGL02174:Stab2	APN	10	86,695,606 (GRCm39)	splice site	probably null
IGL02600:Stab2	APN	10	86,790,123 (GRCm39)	missense	probably damaging	1.00
IGL02666:Stab2	APN	10	86,686,766 (GRCm39)	missense	possibly damaging	0.67
IGL02668:Stab2	APN	10	86,682,027 (GRCm39)	splice site	probably benign
IGL02709:Stab2	APN	10	86,682,029 (GRCm39)	splice site	probably benign
IGL02728:Stab2	APN	10	86,692,420 (GRCm39)	missense	possibly damaging	0.95
IGL02803:Stab2	APN	10	86,786,133 (GRCm39)	splice site	probably benign
IGL02938:Stab2	APN	10	86,707,785 (GRCm39)	missense	possibly damaging	0.77
IGL03033:Stab2	APN	10	86,832,667 (GRCm39)	critical splice donor site	probably null
IGL03238:Stab2	APN	10	86,690,985 (GRCm39)	missense	probably damaging	1.00
IGL03402:Stab2	APN	10	86,805,165 (GRCm39)	missense	probably benign	0.03
prospector	UTSW	10	86,737,431 (GRCm39)	splice site	probably null
songbird	UTSW	10	86,694,016 (GRCm39)	missense	probably damaging	1.00
3-1:Stab2	UTSW	10	86,705,041 (GRCm39)	missense	probably damaging	0.96
F6893:Stab2	UTSW	10	86,691,035 (GRCm39)	missense	probably damaging	1.00
K7371:Stab2	UTSW	10	86,779,153 (GRCm39)	critical splice donor site	probably null
PIT4142001:Stab2	UTSW	10	86,703,039 (GRCm39)	missense	possibly damaging	0.94
PIT4362001:Stab2	UTSW	10	86,697,299 (GRCm39)	nonsense	probably null
R0015:Stab2	UTSW	10	86,679,481 (GRCm39)	missense	probably benign
R0254:Stab2	UTSW	10	86,733,824 (GRCm39)	missense	probably benign
R0333:Stab2	UTSW	10	86,677,491 (GRCm39)	missense	probably benign
R0391:Stab2	UTSW	10	86,783,008 (GRCm39)	missense	probably benign	0.27
R0400:Stab2	UTSW	10	86,708,474 (GRCm39)	missense	probably damaging	1.00
R0433:Stab2	UTSW	10	86,679,355 (GRCm39)	splice site	probably benign
R0440:Stab2	UTSW	10	86,785,792 (GRCm39)	missense	probably benign	0.23
R0743:Stab2	UTSW	10	86,723,759 (GRCm39)	missense	probably damaging	1.00
R0847:Stab2	UTSW	10	86,805,735 (GRCm39)	missense	probably benign	0.00
R0883:Stab2	UTSW	10	86,760,314 (GRCm39)	splice site	probably benign
R1078:Stab2	UTSW	10	86,742,997 (GRCm39)	splice site	probably null
R1118:Stab2	UTSW	10	86,721,582 (GRCm39)	splice site	probably null
R1119:Stab2	UTSW	10	86,695,619 (GRCm39)	missense	possibly damaging	0.51
R1179:Stab2	UTSW	10	86,786,165 (GRCm39)	missense	probably damaging	0.98
R1440:Stab2	UTSW	10	86,697,231 (GRCm39)	splice site	probably null
R1550:Stab2	UTSW	10	86,714,790 (GRCm39)	missense	probably benign	0.01
R1616:Stab2	UTSW	10	86,721,582 (GRCm39)	splice site	probably null
R1728:Stab2	UTSW	10	86,773,903 (GRCm39)	missense	probably benign	0.41
R1768:Stab2	UTSW	10	86,838,872 (GRCm39)	missense	probably damaging	1.00
R1772:Stab2	UTSW	10	86,790,098 (GRCm39)	missense	probably benign	0.06
R1776:Stab2	UTSW	10	86,793,680 (GRCm39)	missense	possibly damaging	0.92
R1784:Stab2	UTSW	10	86,773,903 (GRCm39)	missense	probably benign	0.41
R1892:Stab2	UTSW	10	86,773,913 (GRCm39)	missense	probably damaging	0.99
R1957:Stab2	UTSW	10	86,697,334 (GRCm39)	missense	probably benign	0.13
R1972:Stab2	UTSW	10	86,796,180 (GRCm39)	missense	probably damaging	0.99
R1975:Stab2	UTSW	10	86,732,360 (GRCm39)	critical splice donor site	probably null
R1976:Stab2	UTSW	10	86,732,360 (GRCm39)	critical splice donor site	probably null
R1996:Stab2	UTSW	10	86,838,895 (GRCm39)	missense	probably damaging	1.00
R2085:Stab2	UTSW	10	86,790,023 (GRCm39)	missense	probably damaging	1.00
R2149:Stab2	UTSW	10	86,700,904 (GRCm39)	nonsense	probably null
R2169:Stab2	UTSW	10	86,723,726 (GRCm39)	missense	probably damaging	1.00
R2201:Stab2	UTSW	10	86,776,503 (GRCm39)	missense	probably benign	0.22
R2296:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2297:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2298:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2326:Stab2	UTSW	10	86,790,338 (GRCm39)	critical splice acceptor site	probably null
R2434:Stab2	UTSW	10	86,805,183 (GRCm39)	missense	possibly damaging	0.78
R2519:Stab2	UTSW	10	86,770,704 (GRCm39)	splice site	probably benign
R2696:Stab2	UTSW	10	86,697,363 (GRCm39)	missense	probably benign	0.45
R2883:Stab2	UTSW	10	86,803,550 (GRCm39)	missense	possibly damaging	0.92
R2923:Stab2	UTSW	10	86,697,325 (GRCm39)	missense	probably damaging	1.00
R3711:Stab2	UTSW	10	86,702,572 (GRCm39)	missense	probably damaging	1.00
R3787:Stab2	UTSW	10	86,805,141 (GRCm39)	missense	possibly damaging	0.50
R3834:Stab2	UTSW	10	86,785,776 (GRCm39)	missense	possibly damaging	0.87
R3970:Stab2	UTSW	10	86,714,750 (GRCm39)	missense	probably damaging	0.97
R3979:Stab2	UTSW	10	86,699,320 (GRCm39)	missense	possibly damaging	0.56
R4003:Stab2	UTSW	10	86,693,988 (GRCm39)	missense	probably damaging	1.00
R4088:Stab2	UTSW	10	86,758,049 (GRCm39)	missense	probably damaging	1.00
R4151:Stab2	UTSW	10	86,838,847 (GRCm39)	missense	probably benign	0.12
R4190:Stab2	UTSW	10	86,714,808 (GRCm39)	missense	probably damaging	0.98
R4556:Stab2	UTSW	10	86,803,543 (GRCm39)	missense	possibly damaging	0.95
R4773:Stab2	UTSW	10	86,743,235 (GRCm39)	nonsense	probably null
R4825:Stab2	UTSW	10	86,783,011 (GRCm39)	missense	probably benign	0.08
R4865:Stab2	UTSW	10	86,679,364 (GRCm39)	splice site	probably null
R4871:Stab2	UTSW	10	86,778,099 (GRCm39)	missense	probably damaging	0.99
R4943:Stab2	UTSW	10	86,790,026 (GRCm39)	missense	probably damaging	0.99
R4981:Stab2	UTSW	10	86,796,087 (GRCm39)	missense	probably benign
R4994:Stab2	UTSW	10	86,785,771 (GRCm39)	missense	probably benign
R4999:Stab2	UTSW	10	86,773,773 (GRCm39)	missense	probably damaging	0.97
R5061:Stab2	UTSW	10	86,743,249 (GRCm39)	missense	probably damaging	1.00
R5072:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5073:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5074:Stab2	UTSW	10	86,699,422 (GRCm39)	missense	probably benign	0.23
R5134:Stab2	UTSW	10	86,707,674 (GRCm39)	splice site	probably null
R5213:Stab2	UTSW	10	86,743,061 (GRCm39)	missense	probably damaging	0.99
R5508:Stab2	UTSW	10	86,796,143 (GRCm39)	missense	probably benign	0.01
R5530:Stab2	UTSW	10	86,783,026 (GRCm39)	missense	probably benign	0.04
R5540:Stab2	UTSW	10	86,683,989 (GRCm39)	missense	probably benign	0.30
R5839:Stab2	UTSW	10	86,708,555 (GRCm39)	missense	probably damaging	0.97
R5949:Stab2	UTSW	10	86,805,713 (GRCm39)	missense	possibly damaging	0.87
R6015:Stab2	UTSW	10	86,773,906 (GRCm39)	missense	probably damaging	0.99
R6019:Stab2	UTSW	10	86,838,886 (GRCm39)	missense	probably benign	0.00
R6116:Stab2	UTSW	10	86,743,054 (GRCm39)	missense	probably damaging	1.00
R6131:Stab2	UTSW	10	86,719,642 (GRCm39)	splice site	probably null
R6209:Stab2	UTSW	10	86,758,867 (GRCm39)	missense	possibly damaging	0.94
R6243:Stab2	UTSW	10	86,743,025 (GRCm39)	missense	probably damaging	1.00
R6433:Stab2	UTSW	10	86,737,431 (GRCm39)	splice site	probably null
R6787:Stab2	UTSW	10	86,754,948 (GRCm39)	missense	probably benign	0.07
R6841:Stab2	UTSW	10	86,778,054 (GRCm39)	missense	probably damaging	1.00
R6873:Stab2	UTSW	10	86,697,230 (GRCm39)	critical splice donor site	probably null
R7025:Stab2	UTSW	10	86,686,701 (GRCm39)	missense	probably damaging	1.00
R7043:Stab2	UTSW	10	86,706,110 (GRCm39)	missense	probably damaging	0.99
R7047:Stab2	UTSW	10	86,694,016 (GRCm39)	missense	probably damaging	1.00
R7107:Stab2	UTSW	10	86,741,456 (GRCm39)	missense	possibly damaging	0.96
R7214:Stab2	UTSW	10	86,735,705 (GRCm39)	missense	probably damaging	0.99
R7271:Stab2	UTSW	10	86,838,972 (GRCm39)	splice site	probably null
R7291:Stab2	UTSW	10	86,782,084 (GRCm39)	missense	probably damaging	0.96
R7336:Stab2	UTSW	10	86,805,049 (GRCm39)	nonsense	probably null
R7432:Stab2	UTSW	10	86,721,547 (GRCm39)	missense	probably damaging	0.99
R7580:Stab2	UTSW	10	86,705,028 (GRCm39)	missense	probably benign	0.00
R7622:Stab2	UTSW	10	86,709,766 (GRCm39)	missense	possibly damaging	0.65
R7629:Stab2	UTSW	10	86,719,646 (GRCm39)	critical splice donor site	probably null
R7658:Stab2	UTSW	10	86,816,999 (GRCm39)	missense	probably benign	0.12
R7798:Stab2	UTSW	10	86,793,776 (GRCm39)	missense	probably damaging	0.98
R7835:Stab2	UTSW	10	86,708,483 (GRCm39)	missense	probably benign	0.06
R7845:Stab2	UTSW	10	86,832,758 (GRCm39)	missense	probably benign	0.09
R7863:Stab2	UTSW	10	86,808,745 (GRCm39)	missense	probably benign	0.30
R7885:Stab2	UTSW	10	86,714,776 (GRCm39)	missense	probably benign	0.03
R7904:Stab2	UTSW	10	86,790,056 (GRCm39)	nonsense	probably null
R7947:Stab2	UTSW	10	86,681,897 (GRCm39)	missense	probably benign	0.31
R7963:Stab2	UTSW	10	86,683,887 (GRCm39)	critical splice donor site	probably null
R8014:Stab2	UTSW	10	86,686,767 (GRCm39)	missense	possibly damaging	0.78
R8021:Stab2	UTSW	10	86,741,403 (GRCm39)	missense	possibly damaging	0.69
R8024:Stab2	UTSW	10	86,681,916 (GRCm39)	missense	probably benign	0.34
R8097:Stab2	UTSW	10	86,704,959 (GRCm39)	missense	possibly damaging	0.86
R8281:Stab2	UTSW	10	86,709,728 (GRCm39)	missense	probably damaging	0.98
R8462:Stab2	UTSW	10	86,803,598 (GRCm39)	missense	possibly damaging	0.79
R8670:Stab2	UTSW	10	86,776,587 (GRCm39)	missense	probably damaging	1.00
R8692:Stab2	UTSW	10	86,808,794 (GRCm39)	missense	probably damaging	0.99
R8744:Stab2	UTSW	10	86,805,213 (GRCm39)	missense	probably benign	0.32
R8745:Stab2	UTSW	10	86,805,213 (GRCm39)	missense	probably benign	0.32
R8782:Stab2	UTSW	10	86,735,685 (GRCm39)	missense	probably benign	0.00
R8875:Stab2	UTSW	10	86,832,728 (GRCm39)	missense	probably damaging	1.00
R8978:Stab2	UTSW	10	86,785,782 (GRCm39)	missense	possibly damaging	0.64
R9141:Stab2	UTSW	10	86,704,911 (GRCm39)	missense	probably damaging	1.00
R9248:Stab2	UTSW	10	86,727,481 (GRCm39)	missense	probably damaging	0.98
R9326:Stab2	UTSW	10	86,791,010 (GRCm39)	missense	probably damaging	1.00
R9426:Stab2	UTSW	10	86,704,911 (GRCm39)	missense	probably damaging	1.00
R9568:Stab2	UTSW	10	86,699,420 (GRCm39)	missense	probably damaging	1.00
R9627:Stab2	UTSW	10	86,793,704 (GRCm39)	missense	probably damaging	0.98
R9635:Stab2	UTSW	10	86,686,651 (GRCm39)	nonsense	probably null
R9648:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9649:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9650:Stab2	UTSW	10	86,692,561 (GRCm39)	frame shift	probably null
R9726:Stab2	UTSW	10	86,790,095 (GRCm39)	missense	probably benign	0.00
R9756:Stab2	UTSW	10	86,803,553 (GRCm39)	missense	possibly damaging	0.50
R9786:Stab2	UTSW	10	86,757,997 (GRCm39)	missense	probably benign	0.03
RF061:Stab2	UTSW	10	86,702,622 (GRCm39)	critical splice acceptor site	probably benign
X0023:Stab2	UTSW	10	86,758,062 (GRCm39)	critical splice acceptor site	probably null
X0025:Stab2	UTSW	10	86,723,680 (GRCm39)	missense	probably damaging	1.00
Z1176:Stab2	UTSW	10	86,785,778 (GRCm39)	missense	probably damaging	0.99
Z1177:Stab2	UTSW	10	86,732,460 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AAGCAATTACTGTTCTCCTTGCTGCTG -3'
(R):5'- AGAAATTGTCCAAAGCTCTTCCTCCAC -3'

Sequencing Primer
(F):5'- CTGCTGTCTGGAATGGAGTAGATAC -3'
(R):5'- GTGTAAGCCCACATTTGGTC -3'

Posted On

2013-04-16