Incidental Mutation 'R2511:Tnrc6a'
| ID |
252939 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6a
|
| Ensembl Gene |
ENSMUSG00000052707 |
| Gene Name |
trinucleotide repeat containing 6a |
| Synonyms |
3110054G10Rik, 2010321I05Rik, Tnrc6, CAGH26, D130023A07Rik |
| MMRRC Submission |
040417-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.850)
|
| Stock # |
R2511 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
122723108-122794519 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 122770315 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 702
(V702I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091595
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094053]
[ENSMUST00000205514]
[ENSMUST00000206014]
[ENSMUST00000206888]
|
| AlphaFold |
Q3UHK8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000094053
AA Change: V702I
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000091595
Gene: ENSMUSG00000052707
AA Change: V702I
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
568 |
590 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
690 |
853 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
858 |
871 |
N/A |
INTRINSIC |
|
Pfam:Ago_hook
|
1028 |
1190 |
1.2e-29 |
PFAM |
|
low complexity region
|
1284 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1301 |
1316 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1392 |
N/A |
INTRINSIC |
|
Pfam:TNRC6-PABC_bdg
|
1439 |
1714 |
1.5e-126 |
PFAM |
|
RRM
|
1717 |
1784 |
4.95e-2 |
SMART |
|
low complexity region
|
1808 |
1820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205449
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205514
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205732
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000205760
AA Change: V154I
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205789
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206014
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000211170
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206922
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206888
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 94.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The human protein associates with messenger RNAs and argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies, and inhibiting its expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit partial embryonic lethality during organogenesis associated with impaired hematopoiesis. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(21) : Gene trapped(21) |
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9330159F19Rik |
T |
A |
10: 29,097,902 (GRCm39) |
C100S |
probably damaging |
Het |
| Abcc8 |
C |
T |
7: 45,800,204 (GRCm39) |
R526H |
probably damaging |
Het |
| Acad10 |
G |
A |
5: 121,769,630 (GRCm39) |
P609S |
probably benign |
Het |
| Acod1 |
A |
T |
14: 103,288,775 (GRCm39) |
D95V |
probably damaging |
Het |
| Acsm5 |
A |
T |
7: 119,129,677 (GRCm39) |
I130F |
possibly damaging |
Het |
| Ago4 |
A |
T |
4: 126,410,864 (GRCm39) |
D208E |
probably damaging |
Het |
| Agrn |
A |
T |
4: 156,250,881 (GRCm39) |
|
probably null |
Het |
| Ankar |
A |
T |
1: 72,697,853 (GRCm39) |
I791K |
probably damaging |
Het |
| Ano10 |
A |
G |
9: 122,088,011 (GRCm39) |
V364A |
probably damaging |
Het |
| Arhgap9 |
T |
C |
10: 127,164,854 (GRCm39) |
|
probably null |
Het |
| Arsi |
G |
A |
18: 61,049,666 (GRCm39) |
C183Y |
probably damaging |
Het |
| Ascl2 |
T |
G |
7: 142,521,953 (GRCm39) |
E97A |
probably damaging |
Het |
| Bcl2a1a |
C |
T |
9: 88,839,506 (GRCm39) |
R135W |
probably damaging |
Het |
| Bms1 |
C |
T |
6: 118,368,114 (GRCm39) |
|
probably null |
Het |
| Bysl |
T |
A |
17: 47,915,260 (GRCm39) |
T163S |
probably benign |
Het |
| Card10 |
A |
G |
15: 78,664,473 (GRCm39) |
I821T |
probably benign |
Het |
| Cc2d2a |
A |
T |
5: 43,892,737 (GRCm39) |
Q1433L |
probably damaging |
Het |
| Cchcr1 |
T |
C |
17: 35,841,410 (GRCm39) |
S809P |
probably benign |
Het |
| Ccz1 |
G |
T |
5: 143,949,815 (GRCm39) |
T70K |
probably damaging |
Het |
| Cdc25c |
G |
C |
18: 34,871,292 (GRCm39) |
L275V |
probably damaging |
Het |
| Cep164 |
A |
T |
9: 45,686,547 (GRCm39) |
L729Q |
probably damaging |
Het |
| Clcn6 |
A |
G |
4: 148,101,951 (GRCm39) |
|
probably null |
Het |
| Clcn7 |
T |
A |
17: 25,374,420 (GRCm39) |
V507E |
probably damaging |
Het |
| Cracdl |
T |
C |
1: 37,664,381 (GRCm39) |
M506V |
probably benign |
Het |
| Ctso |
A |
C |
3: 81,840,041 (GRCm39) |
T24P |
probably damaging |
Het |
| Dis3l2 |
A |
T |
1: 86,917,980 (GRCm39) |
N543I |
probably benign |
Het |
| Dnah12 |
A |
T |
14: 26,491,907 (GRCm39) |
Y1114F |
possibly damaging |
Het |
| Emx1 |
A |
G |
6: 85,181,033 (GRCm39) |
D250G |
probably benign |
Het |
| Epha4 |
G |
A |
1: 77,488,339 (GRCm39) |
A47V |
possibly damaging |
Het |
| Fam149b |
A |
C |
14: 20,428,524 (GRCm39) |
N341T |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,782,001 (GRCm39) |
K62R |
probably damaging |
Het |
| Fsip2 |
T |
C |
2: 82,816,782 (GRCm39) |
S4172P |
probably benign |
Het |
| Gbp3 |
A |
G |
3: 142,276,343 (GRCm39) |
R480G |
probably benign |
Het |
| Get3 |
A |
G |
8: 85,746,395 (GRCm39) |
V151A |
possibly damaging |
Het |
| Gja8 |
T |
G |
3: 96,827,033 (GRCm39) |
T210P |
probably damaging |
Het |
| Gm5431 |
T |
A |
11: 48,779,536 (GRCm39) |
N740I |
probably benign |
Het |
| Gm9930 |
T |
C |
10: 9,410,446 (GRCm39) |
|
noncoding transcript |
Het |
| Gstt4 |
C |
T |
10: 75,650,959 (GRCm39) |
C221Y |
probably benign |
Het |
| Gzmg |
A |
T |
14: 56,395,832 (GRCm39) |
D42E |
probably benign |
Het |
| Hoxd12 |
G |
A |
2: 74,505,815 (GRCm39) |
A129T |
possibly damaging |
Het |
| Hs2st1 |
G |
A |
3: 144,275,691 (GRCm39) |
|
probably benign |
Het |
| Ifnlr1 |
G |
T |
4: 135,432,559 (GRCm39) |
D332Y |
probably damaging |
Het |
| Igsf10 |
T |
C |
3: 59,239,287 (GRCm39) |
D298G |
probably damaging |
Het |
| Irf1 |
T |
C |
11: 53,664,617 (GRCm39) |
V108A |
probably damaging |
Het |
| Jsrp1 |
C |
G |
10: 80,648,140 (GRCm39) |
S36T |
probably benign |
Het |
| Kcnq5 |
T |
A |
1: 21,576,006 (GRCm39) |
R233* |
probably null |
Het |
| Kif7 |
T |
C |
7: 79,352,012 (GRCm39) |
K917E |
probably damaging |
Het |
| Krt7 |
A |
C |
15: 101,310,538 (GRCm39) |
I62L |
probably benign |
Het |
| Lifr |
A |
G |
15: 7,196,397 (GRCm39) |
T194A |
probably benign |
Het |
| Ltbp2 |
T |
C |
12: 84,851,183 (GRCm39) |
|
probably null |
Het |
| Maco1 |
A |
G |
4: 134,531,699 (GRCm39) |
S657P |
probably damaging |
Het |
| Man2c1 |
A |
G |
9: 57,048,672 (GRCm39) |
|
probably null |
Het |
| Met |
T |
C |
6: 17,491,966 (GRCm39) |
S243P |
probably damaging |
Het |
| Mllt10 |
C |
A |
2: 18,069,935 (GRCm39) |
D30E |
possibly damaging |
Het |
| Mre11a |
A |
C |
9: 14,707,065 (GRCm39) |
|
probably null |
Het |
| Mroh9 |
A |
G |
1: 162,866,514 (GRCm39) |
S710P |
probably benign |
Het |
| Mvk |
C |
A |
5: 114,588,459 (GRCm39) |
Y116* |
probably null |
Het |
| Myh1 |
A |
G |
11: 67,096,423 (GRCm39) |
I301V |
probably benign |
Het |
| Ncf1 |
T |
C |
5: 134,254,552 (GRCm39) |
D184G |
probably damaging |
Het |
| Nxpe4 |
T |
C |
9: 48,304,533 (GRCm39) |
F207L |
probably damaging |
Het |
| Or2ag18 |
G |
T |
7: 106,405,168 (GRCm39) |
P167H |
probably damaging |
Het |
| Or2y1b |
T |
G |
11: 49,209,048 (GRCm39) |
L225R |
probably damaging |
Het |
| Or4k51 |
T |
A |
2: 111,584,661 (GRCm39) |
N22K |
probably benign |
Het |
| Or52b1 |
A |
T |
7: 104,978,817 (GRCm39) |
I194N |
probably damaging |
Het |
| Or5b24 |
T |
A |
19: 12,912,537 (GRCm39) |
M145K |
possibly damaging |
Het |
| Or5w14 |
T |
C |
2: 87,541,392 (GRCm39) |
N286S |
probably damaging |
Het |
| Pcdh1 |
G |
A |
18: 38,332,532 (GRCm39) |
T296M |
possibly damaging |
Het |
| Pcdh15 |
A |
G |
10: 74,481,828 (GRCm39) |
D391G |
possibly damaging |
Het |
| Pcdha7 |
C |
A |
18: 37,107,786 (GRCm39) |
D270E |
probably damaging |
Het |
| Pgam1 |
C |
A |
19: 41,904,315 (GRCm39) |
S137R |
probably damaging |
Het |
| Pitpnm2 |
T |
C |
5: 124,274,389 (GRCm39) |
E240G |
probably damaging |
Het |
| Plce1 |
T |
G |
19: 38,748,498 (GRCm39) |
I1729S |
probably damaging |
Het |
| Plppr4 |
G |
T |
3: 117,125,355 (GRCm39) |
N161K |
probably damaging |
Het |
| Pramel27 |
G |
A |
4: 143,578,561 (GRCm39) |
V274I |
probably benign |
Het |
| Prkce |
T |
A |
17: 86,932,754 (GRCm39) |
I578N |
probably damaging |
Het |
| Prss58 |
A |
C |
6: 40,874,734 (GRCm39) |
S36A |
probably damaging |
Het |
| Ptprm |
T |
C |
17: 67,000,773 (GRCm39) |
H1128R |
probably damaging |
Het |
| Rgs9 |
T |
C |
11: 109,159,798 (GRCm39) |
Y178C |
probably benign |
Het |
| Rubcn |
T |
C |
16: 32,667,624 (GRCm39) |
N179S |
probably damaging |
Het |
| Sh3bp1 |
C |
T |
15: 78,795,706 (GRCm39) |
P612S |
probably damaging |
Het |
| Sh3bp5 |
G |
A |
14: 31,133,586 (GRCm39) |
T82M |
probably damaging |
Het |
| Shank2 |
A |
G |
7: 143,965,314 (GRCm39) |
Y974C |
probably damaging |
Het |
| Slc9c1 |
T |
C |
16: 45,365,099 (GRCm39) |
I144T |
possibly damaging |
Het |
| Slf2 |
T |
C |
19: 44,930,045 (GRCm39) |
I374T |
possibly damaging |
Het |
| Snx13 |
A |
G |
12: 35,188,080 (GRCm39) |
D786G |
probably benign |
Het |
| Spcs3 |
A |
G |
8: 54,976,389 (GRCm39) |
V151A |
possibly damaging |
Het |
| Sstr2 |
A |
T |
11: 113,515,749 (GRCm39) |
I223F |
probably damaging |
Het |
| Stac3 |
T |
C |
10: 127,339,787 (GRCm39) |
|
probably null |
Het |
| Tas1r2 |
A |
G |
4: 139,387,162 (GRCm39) |
N207S |
probably damaging |
Het |
| Tectb |
C |
G |
19: 55,169,431 (GRCm39) |
|
probably benign |
Het |
| Tgm5 |
T |
C |
2: 120,907,429 (GRCm39) |
E98G |
possibly damaging |
Het |
| Tktl2 |
A |
G |
8: 66,965,504 (GRCm39) |
E354G |
probably benign |
Het |
| Tmem94 |
G |
A |
11: 115,682,787 (GRCm39) |
R608H |
probably damaging |
Het |
| Trappc10 |
A |
G |
10: 78,047,357 (GRCm39) |
S380P |
possibly damaging |
Het |
| Trim24 |
G |
A |
6: 37,880,587 (GRCm39) |
|
probably null |
Het |
| Ugt1a2 |
A |
G |
1: 88,128,846 (GRCm39) |
Y163C |
probably damaging |
Het |
| Vmn1r215 |
A |
G |
13: 23,260,343 (GRCm39) |
I128V |
probably benign |
Het |
| Vmn2r50 |
T |
A |
7: 9,781,640 (GRCm39) |
E368D |
possibly damaging |
Het |
| Vmn2r59 |
T |
C |
7: 41,693,190 (GRCm39) |
N470S |
probably damaging |
Het |
| Vps45 |
T |
C |
3: 95,948,757 (GRCm39) |
T333A |
probably benign |
Het |
| Zbtb44 |
T |
A |
9: 30,965,539 (GRCm39) |
D316E |
probably damaging |
Het |
| Zdhhc1 |
C |
T |
8: 106,210,190 (GRCm39) |
V76M |
probably benign |
Het |
| Zfp235 |
T |
C |
7: 23,841,549 (GRCm39) |
F656S |
probably damaging |
Het |
|
| Other mutations in Tnrc6a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00335:Tnrc6a
|
APN |
7 |
122,770,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00580:Tnrc6a
|
APN |
7 |
122,773,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Tnrc6a
|
APN |
7 |
122,770,717 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02004:Tnrc6a
|
APN |
7 |
122,780,589 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02142:Tnrc6a
|
APN |
7 |
122,751,414 (GRCm39) |
intron |
probably benign |
|
|
IGL02220:Tnrc6a
|
APN |
7 |
122,769,679 (GRCm39) |
missense |
probably benign |
|
|
IGL02436:Tnrc6a
|
APN |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02670:Tnrc6a
|
APN |
7 |
122,770,535 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02743:Tnrc6a
|
APN |
7 |
122,770,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
0152:Tnrc6a
|
UTSW |
7 |
122,779,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Tnrc6a
|
UTSW |
7 |
122,770,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Tnrc6a
|
UTSW |
7 |
122,785,951 (GRCm39) |
splice site |
probably benign |
|
|
R0566:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0600:Tnrc6a
|
UTSW |
7 |
122,771,039 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0751:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1184:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1319:Tnrc6a
|
UTSW |
7 |
122,783,474 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Tnrc6a
|
UTSW |
7 |
122,776,098 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1709:Tnrc6a
|
UTSW |
7 |
122,769,205 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1776:Tnrc6a
|
UTSW |
7 |
122,770,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Tnrc6a
|
UTSW |
7 |
122,792,140 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1807:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R1876:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2010:Tnrc6a
|
UTSW |
7 |
122,770,269 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2086:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2089:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2830:Tnrc6a
|
UTSW |
7 |
122,792,172 (GRCm39) |
makesense |
probably null |
|
|
R2850:Tnrc6a
|
UTSW |
7 |
122,779,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Tnrc6a
|
UTSW |
7 |
122,780,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4028:Tnrc6a
|
UTSW |
7 |
122,769,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4235:Tnrc6a
|
UTSW |
7 |
122,770,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4439:Tnrc6a
|
UTSW |
7 |
122,751,405 (GRCm39) |
nonsense |
probably null |
|
|
R4525:Tnrc6a
|
UTSW |
7 |
122,779,005 (GRCm39) |
missense |
probably benign |
|
|
R4578:Tnrc6a
|
UTSW |
7 |
122,783,444 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4613:Tnrc6a
|
UTSW |
7 |
122,783,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4711:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Tnrc6a
|
UTSW |
7 |
122,791,313 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4746:Tnrc6a
|
UTSW |
7 |
122,789,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4892:Tnrc6a
|
UTSW |
7 |
122,769,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Tnrc6a
|
UTSW |
7 |
122,791,836 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4967:Tnrc6a
|
UTSW |
7 |
122,789,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5064:Tnrc6a
|
UTSW |
7 |
122,785,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5239:Tnrc6a
|
UTSW |
7 |
122,785,842 (GRCm39) |
missense |
probably benign |
|
|
R5604:Tnrc6a
|
UTSW |
7 |
122,773,459 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5805:Tnrc6a
|
UTSW |
7 |
122,769,299 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5942:Tnrc6a
|
UTSW |
7 |
122,785,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Tnrc6a
|
UTSW |
7 |
122,781,603 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6212:Tnrc6a
|
UTSW |
7 |
122,742,965 (GRCm39) |
splice site |
probably null |
|
|
R6284:Tnrc6a
|
UTSW |
7 |
122,770,558 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6417:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6420:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6575:Tnrc6a
|
UTSW |
7 |
122,769,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6760:Tnrc6a
|
UTSW |
7 |
122,771,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6886:Tnrc6a
|
UTSW |
7 |
122,786,668 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6968:Tnrc6a
|
UTSW |
7 |
122,781,650 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7216:Tnrc6a
|
UTSW |
7 |
122,770,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7260:Tnrc6a
|
UTSW |
7 |
122,785,813 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7299:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
|
|
R7322:Tnrc6a
|
UTSW |
7 |
122,770,731 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7500:Tnrc6a
|
UTSW |
7 |
122,772,673 (GRCm39) |
splice site |
probably null |
|
|
R7872:Tnrc6a
|
UTSW |
7 |
122,779,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8270:Tnrc6a
|
UTSW |
7 |
122,769,294 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8313:Tnrc6a
|
UTSW |
7 |
122,769,936 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8348:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8390:Tnrc6a
|
UTSW |
7 |
122,761,794 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8448:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8514:Tnrc6a
|
UTSW |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R8767:Tnrc6a
|
UTSW |
7 |
122,783,133 (GRCm39) |
unclassified |
probably benign |
|
|
R9047:Tnrc6a
|
UTSW |
7 |
122,778,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9147:Tnrc6a
|
UTSW |
7 |
122,785,667 (GRCm39) |
intron |
probably benign |
|
|
R9153:Tnrc6a
|
UTSW |
7 |
122,773,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9166:Tnrc6a
|
UTSW |
7 |
122,786,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9179:Tnrc6a
|
UTSW |
7 |
122,791,881 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9192:Tnrc6a
|
UTSW |
7 |
122,789,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Tnrc6a
|
UTSW |
7 |
122,778,958 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9778:Tnrc6a
|
UTSW |
7 |
122,769,635 (GRCm39) |
missense |
probably benign |
0.43 |
|
X0064:Tnrc6a
|
UTSW |
7 |
122,769,021 (GRCm39) |
missense |
probably benign |
0.28 |
|
Z1176:Tnrc6a
|
UTSW |
7 |
122,761,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCAAAACAGTGTGTGGGCC -3'
(R):5'- CCTCAGAGTAGGTTTGGGATCAC -3'
Sequencing Primer
(F):5'- CAGTGTGTGGGCCAAAGC -3'
(R):5'- CACCCTGATACAGATGAGGTATC -3'
|
| Posted On |
2014-12-04 |
Incidental Mutation