Mutagenetix > Incidental Mutation

Incidental Mutation 'R2517:Polq'

254007

Institutional Source

Beutler Lab

Gene Symbol

Polq

Ensembl Gene

ENSMUSG00000034206

Gene Name

polymerase (DNA directed), theta

Synonyms

A430110D14Rik

MMRRC Submission

040421-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.492) question?

Stock #

R2517 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

36832148-36915779 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 36909687 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Aspartic acid at position 2078 (G2078D)

Ref Sequence

ENSEMBL: ENSMUSP00000071396 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000054034] [ENSMUST00000071452] [ENSMUST00000182946] [ENSMUST00000183112]

AlphaFold

Q8CGS6

Predicted Effect

possibly damaging
Transcript: ENSMUST00000054034
AA Change: G2357D

PolyPhen 2 Score 0.849 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000059757
Gene: ENSMUSG00000034206
AA Change: G2357D

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
DEXDc	87	298	4.09e-18	SMART
HELICc	398	484	4.02e-17	SMART
Blast:DEXDc	485	550	2e-25	BLAST
low complexity region	609	626	N/A	INTRINSIC
PDB:2ZJA\|A	712	826	5e-9	PDB
low complexity region	845	852	N/A	INTRINSIC
low complexity region	898	911	N/A	INTRINSIC
low complexity region	1126	1149	N/A	INTRINSIC
low complexity region	1813	1822	N/A	INTRINSIC
POLAc	2265	2504	3.3e-101	SMART
low complexity region	2521	2531	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000071452
AA Change: G2078D

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000071396
Gene: ENSMUSG00000034206
AA Change: G2078D

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
Pfam:DEAD	92	216	5.9e-12	PFAM
low complexity region	330	347	N/A	INTRINSIC
PDB:2ZJA\|A	433	547	5e-9	PDB
low complexity region	566	573	N/A	INTRINSIC
low complexity region	619	632	N/A	INTRINSIC
low complexity region	847	870	N/A	INTRINSIC
low complexity region	1534	1543	N/A	INTRINSIC
POLAc	1986	2225	3.3e-101	SMART
low complexity region	2242	2252	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000182717

Predicted Effect

probably benign
Transcript: ENSMUST00000182946

SMART Domains

Protein: ENSMUSP00000138685
Gene: ENSMUSG00000034206

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
Pfam:DEAD	92	164	1.3e-9	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000183112

SMART Domains

Protein: ENSMUSP00000138648
Gene: ENSMUSG00000034206

Domain	Start	End	E-Value	Type
low complexity region	2	29	N/A	INTRINSIC
low complexity region	38	55	N/A	INTRINSIC
Pfam:DEAD	92	164	1.3e-9	PFAM

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 97.1%
20x: 94.2%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Animals carrying a homozygous mutation at this locus display elevated levels of chromosomal damage. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 60 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adcy4	C	A	14: 56,019,403 (GRCm39)	E82D	probably damaging	Het
Ago1	G	A	4: 126,333,732 (GRCm39)	R486*	probably null	Het
Ago2	T	A	15: 72,996,091 (GRCm39)	N346I	possibly damaging	Het
Apol11a	A	T	15: 77,401,395 (GRCm39)	D294V	probably benign	Het
Atp13a5	A	G	16: 29,116,215 (GRCm39)	F634L	possibly damaging	Het
Atp2a2	G	A	5: 122,595,576 (GRCm39)	P953L	probably damaging	Het
Brca2	A	G	5: 150,463,137 (GRCm39)	D967G	probably benign	Het
Bud13	A	T	9: 46,199,446 (GRCm39)	H269L	probably benign	Het
Cachd1	A	T	4: 100,838,079 (GRCm39)		probably null	Het
Cog3	T	C	14: 75,979,182 (GRCm39)	D188G	probably benign	Het
Col15a1	T	C	4: 47,208,492 (GRCm39)	S20P	probably damaging	Het
Col4a3	A	G	1: 82,658,431 (GRCm39)	D838G	unknown	Het
Cwh43	A	T	5: 73,578,886 (GRCm39)	T298S	probably benign	Het
Dip2c	A	G	13: 9,659,041 (GRCm39)	R847G	probably damaging	Het
Dnah2	C	T	11: 69,407,470 (GRCm39)	D438N	probably damaging	Het
Drg2	T	C	11: 60,358,954 (GRCm39)	V358A	probably damaging	Het
Eif4enif1	T	A	11: 3,171,168 (GRCm39)	W220R	probably damaging	Het
Enpp2	A	T	15: 54,783,090 (GRCm39)	I75K	probably damaging	Het
Fam110c	T	C	12: 31,125,238 (GRCm39)	I400T	probably damaging	Het
Fam193b	C	A	13: 55,690,629 (GRCm39)	R711L	probably damaging	Het
Fgfr1	T	C	8: 26,053,462 (GRCm39)	Y246H	probably damaging	Het
Frs3	G	A	17: 48,013,997 (GRCm39)	R230Q	probably benign	Het
Galnt5	A	G	2: 57,889,425 (GRCm39)	K342E	probably benign	Het
Glrb	A	T	3: 80,769,054 (GRCm39)	L189Q	probably damaging	Het
Gmeb2	T	C	2: 180,900,819 (GRCm39)	T193A	probably benign	Het
Gnl3	A	G	14: 30,736,120 (GRCm39)	S307P	probably damaging	Het
Golim4	A	T	3: 75,800,166 (GRCm39)	F443I	probably benign	Het
Hivep2	C	A	10: 14,004,713 (GRCm39)	T437K	probably benign	Het
Klf10	A	C	15: 38,297,357 (GRCm39)	Y228D	probably benign	Het
Klrc3	A	T	6: 129,616,520 (GRCm39)	W166R	probably damaging	Het
Kng2	A	T	16: 22,807,065 (GRCm39)	I378N	probably benign	Het
Map3k10	T	C	7: 27,362,688 (GRCm39)	K466R	possibly damaging	Het
Mrrf	C	T	2: 36,079,109 (GRCm39)	T245M	probably benign	Het
Msi1	A	G	5: 115,583,517 (GRCm39)	Y239C	probably damaging	Het
Nfasc	A	G	1: 132,525,501 (GRCm39)		probably null	Het
Or1x6	T	A	11: 50,939,300 (GRCm39)	L122Q	probably damaging	Het
Or7g25	A	T	9: 19,160,357 (GRCm39)	C113S	probably benign	Het
P3r3urf	A	G	4: 116,030,791 (GRCm39)	D65G	probably benign	Het
Pkd1l1	T	C	11: 8,908,900 (GRCm39)	E368G	unknown	Het
Ppfibp1	A	C	6: 146,893,942 (GRCm39)	I134L	probably damaging	Het
Rasip1	A	T	7: 45,284,247 (GRCm39)	I608F	probably damaging	Het
Ripk3	A	T	14: 56,025,492 (GRCm39)	V24E	probably damaging	Het
Rtkn	T	A	6: 83,124,526 (GRCm39)	I110N	probably damaging	Het
Scn1a	C	T	2: 66,104,176 (GRCm39)	V1695I	probably damaging	Het
Shank2	A	G	7: 143,606,042 (GRCm39)	N75S	possibly damaging	Het
Snu13	C	A	15: 81,928,182 (GRCm39)	A14S	probably benign	Het
Snx27	A	C	3: 94,438,541 (GRCm39)	D231E	probably damaging	Het
Spef2	A	G	15: 9,725,283 (GRCm39)	I158T	possibly damaging	Het
Sptb	A	G	12: 76,696,643 (GRCm39)	I19T	possibly damaging	Het
Ssu72	T	C	4: 155,817,970 (GRCm39)	L175P	probably damaging	Het
Tcstv2a	T	A	13: 120,725,475 (GRCm39)	C46*	probably null	Het
Tecr	C	T	8: 84,299,204 (GRCm39)	V248I	probably benign	Het
Tnfrsf13b	T	G	11: 61,032,302 (GRCm39)	S59A	probably benign	Het
Tom1l1	T	C	11: 90,561,951 (GRCm39)	T150A	possibly damaging	Het
Ubr3	A	T	2: 69,766,362 (GRCm39)	Y410F	probably damaging	Het
Vmn2r108	A	G	17: 20,692,577 (GRCm39)	I93T	probably damaging	Het
Vmn2r19	A	G	6: 123,306,937 (GRCm39)	T482A	probably benign	Het
Vstm4	T	A	14: 32,585,664 (GRCm39)	M77K	probably benign	Het
Zbtb17	C	T	4: 141,191,896 (GRCm39)	T309I	probably damaging	Het
Zfp957	T	C	14: 79,451,494 (GRCm39)	T102A	probably damaging	Het

Other mutations in Polq

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00336:Polq	APN	16	36,885,609 (GRCm39)	splice site	probably benign
IGL00539:Polq	APN	16	36,880,931 (GRCm39)	missense	probably damaging	0.98
IGL00960:Polq	APN	16	36,880,874 (GRCm39)	missense	probably damaging	0.96
IGL01100:Polq	APN	16	36,881,474 (GRCm39)	missense	probably benign
IGL01112:Polq	APN	16	36,837,671 (GRCm39)	missense	probably damaging	1.00
IGL01138:Polq	APN	16	36,866,231 (GRCm39)	missense	possibly damaging	0.94
IGL01432:Polq	APN	16	36,892,184 (GRCm39)	splice site	probably benign
IGL01522:Polq	APN	16	36,848,265 (GRCm39)	missense	probably damaging	1.00
IGL01565:Polq	APN	16	36,833,475 (GRCm39)	missense	probably benign	0.00
IGL01592:Polq	APN	16	36,855,212 (GRCm39)	missense	probably benign	0.01
IGL01690:Polq	APN	16	36,883,200 (GRCm39)	missense	probably damaging	0.97
IGL01943:Polq	APN	16	36,881,805 (GRCm39)	missense	possibly damaging	0.47
IGL02531:Polq	APN	16	36,882,736 (GRCm39)	missense	possibly damaging	0.75
IGL02553:Polq	APN	16	36,862,130 (GRCm39)	missense	probably damaging	1.00
IGL02623:Polq	APN	16	36,880,737 (GRCm39)	missense	probably benign	0.04
IGL02692:Polq	APN	16	36,880,989 (GRCm39)	missense	probably damaging	1.00
IGL02717:Polq	APN	16	36,843,102 (GRCm39)	missense	probably damaging	1.00
IGL02937:Polq	APN	16	36,833,471 (GRCm39)	missense	probably benign	0.14
IGL02959:Polq	APN	16	36,906,928 (GRCm39)	missense	probably damaging	1.00
IGL03086:Polq	APN	16	36,911,411 (GRCm39)	missense	probably benign	0.02
IGL03141:Polq	APN	16	36,837,720 (GRCm39)	splice site	probably benign
IGL03302:Polq	APN	16	36,892,134 (GRCm39)	missense	probably damaging	1.00
IGL03393:Polq	APN	16	36,865,156 (GRCm39)	missense	probably damaging	1.00
R0013_Polq_667	UTSW	16	36,882,201 (GRCm39)	missense	possibly damaging	0.56
R4238_Polq_233	UTSW	16	36,833,543 (GRCm39)	missense	probably damaging	1.00
R4280_polq_867	UTSW	16	36,902,419 (GRCm39)	missense	probably damaging	1.00
G1Funyon:Polq	UTSW	16	36,882,181 (GRCm39)	missense	probably damaging	1.00
PIT4403001:Polq	UTSW	16	36,880,949 (GRCm39)	missense	probably benign	0.00
R0013:Polq	UTSW	16	36,882,201 (GRCm39)	missense	possibly damaging	0.56
R0082:Polq	UTSW	16	36,837,619 (GRCm39)	missense	probably benign	0.01
R0212:Polq	UTSW	16	36,887,216 (GRCm39)	missense	probably damaging	0.99
R0387:Polq	UTSW	16	36,909,679 (GRCm39)	missense	probably damaging	1.00
R0387:Polq	UTSW	16	36,849,792 (GRCm39)	missense	probably damaging	1.00
R0427:Polq	UTSW	16	36,882,355 (GRCm39)	nonsense	probably null
R0454:Polq	UTSW	16	36,855,252 (GRCm39)	missense	probably damaging	0.98
R0513:Polq	UTSW	16	36,914,864 (GRCm39)	missense	probably damaging	1.00
R0622:Polq	UTSW	16	36,881,355 (GRCm39)	missense	probably benign	0.02
R0848:Polq	UTSW	16	36,882,492 (GRCm39)	missense	probably benign	0.08
R1142:Polq	UTSW	16	36,833,579 (GRCm39)	missense	probably damaging	0.98
R1218:Polq	UTSW	16	36,849,808 (GRCm39)	missense	possibly damaging	0.93
R1331:Polq	UTSW	16	36,862,109 (GRCm39)	missense	probably damaging	1.00
R1398:Polq	UTSW	16	36,882,857 (GRCm39)	missense	possibly damaging	0.87
R1424:Polq	UTSW	16	36,906,890 (GRCm39)	missense	probably damaging	1.00
R1644:Polq	UTSW	16	36,880,626 (GRCm39)	missense	probably damaging	0.96
R1777:Polq	UTSW	16	36,880,586 (GRCm39)	missense	possibly damaging	0.94
R1820:Polq	UTSW	16	36,849,780 (GRCm39)	missense	possibly damaging	0.48
R1854:Polq	UTSW	16	36,882,471 (GRCm39)	missense	probably benign	0.01
R1880:Polq	UTSW	16	36,906,954 (GRCm39)	missense	possibly damaging	0.90
R1932:Polq	UTSW	16	36,882,666 (GRCm39)	missense	possibly damaging	0.92
R2008:Polq	UTSW	16	36,882,844 (GRCm39)	missense	probably damaging	0.96
R2014:Polq	UTSW	16	36,898,728 (GRCm39)	missense	probably damaging	1.00
R2026:Polq	UTSW	16	36,883,107 (GRCm39)	missense	possibly damaging	0.93
R2178:Polq	UTSW	16	36,883,191 (GRCm39)	missense	probably damaging	1.00
R2259:Polq	UTSW	16	36,882,459 (GRCm39)	missense	probably benign	0.03
R2266:Polq	UTSW	16	36,882,515 (GRCm39)	missense	possibly damaging	0.59
R2305:Polq	UTSW	16	36,882,699 (GRCm39)	missense	probably damaging	0.99
R2370:Polq	UTSW	16	36,894,301 (GRCm39)	missense	probably damaging	1.00
R2504:Polq	UTSW	16	36,832,304 (GRCm39)	missense	unknown
R2697:Polq	UTSW	16	36,862,515 (GRCm39)	missense	probably damaging	1.00
R2858:Polq	UTSW	16	36,883,115 (GRCm39)	missense	possibly damaging	0.88
R3436:Polq	UTSW	16	36,882,699 (GRCm39)	missense	probably damaging	0.99
R3437:Polq	UTSW	16	36,882,699 (GRCm39)	missense	probably damaging	0.99
R3699:Polq	UTSW	16	36,862,518 (GRCm39)	missense	probably damaging	1.00
R3838:Polq	UTSW	16	36,898,711 (GRCm39)	missense	probably damaging	1.00
R3875:Polq	UTSW	16	36,894,389 (GRCm39)	missense	probably damaging	0.99
R4050:Polq	UTSW	16	36,913,182 (GRCm39)	critical splice acceptor site	probably null
R4172:Polq	UTSW	16	36,881,120 (GRCm39)	missense	probably benign	0.02
R4238:Polq	UTSW	16	36,833,543 (GRCm39)	missense	probably damaging	1.00
R4240:Polq	UTSW	16	36,833,543 (GRCm39)	missense	probably damaging	1.00
R4280:Polq	UTSW	16	36,902,419 (GRCm39)	missense	probably damaging	1.00
R4296:Polq	UTSW	16	36,881,663 (GRCm39)	missense	possibly damaging	0.94
R4360:Polq	UTSW	16	36,880,701 (GRCm39)	missense	probably benign	0.00
R4373:Polq	UTSW	16	36,833,543 (GRCm39)	missense	probably damaging	1.00
R4375:Polq	UTSW	16	36,833,543 (GRCm39)	missense	probably damaging	1.00
R4376:Polq	UTSW	16	36,833,543 (GRCm39)	missense	probably damaging	1.00
R4509:Polq	UTSW	16	36,868,925 (GRCm39)	missense	probably damaging	1.00
R4510:Polq	UTSW	16	36,868,925 (GRCm39)	missense	probably damaging	1.00
R4511:Polq	UTSW	16	36,868,925 (GRCm39)	missense	probably damaging	1.00
R4543:Polq	UTSW	16	36,881,147 (GRCm39)	missense	probably benign	0.43
R4633:Polq	UTSW	16	36,868,904 (GRCm39)	missense	probably damaging	1.00
R4739:Polq	UTSW	16	36,862,109 (GRCm39)	missense	probably damaging	1.00
R4834:Polq	UTSW	16	36,848,176 (GRCm39)	missense	probably damaging	1.00
R4841:Polq	UTSW	16	36,869,145 (GRCm39)	critical splice donor site	probably null
R4842:Polq	UTSW	16	36,869,145 (GRCm39)	critical splice donor site	probably null
R4937:Polq	UTSW	16	36,848,274 (GRCm39)	missense	probably benign	0.01
R4955:Polq	UTSW	16	36,881,444 (GRCm39)	missense	probably benign	0.32
R4992:Polq	UTSW	16	36,881,524 (GRCm39)	missense	possibly damaging	0.59
R5008:Polq	UTSW	16	36,882,749 (GRCm39)	missense	probably benign
R5221:Polq	UTSW	16	36,862,540 (GRCm39)	missense	probably damaging	0.98
R5254:Polq	UTSW	16	36,909,681 (GRCm39)	missense	probably damaging	1.00
R5292:Polq	UTSW	16	36,881,745 (GRCm39)	missense	probably damaging	1.00
R5375:Polq	UTSW	16	36,903,146 (GRCm39)	missense	probably damaging	1.00
R5480:Polq	UTSW	16	36,833,652 (GRCm39)	splice site	probably benign
R5552:Polq	UTSW	16	36,914,872 (GRCm39)	missense	possibly damaging	0.93
R5591:Polq	UTSW	16	36,832,247 (GRCm39)	utr 5 prime	probably benign
R5653:Polq	UTSW	16	36,860,896 (GRCm39)	missense	probably damaging	1.00
R5708:Polq	UTSW	16	36,881,380 (GRCm39)	missense	probably damaging	0.98
R5754:Polq	UTSW	16	36,837,625 (GRCm39)	missense	probably benign
R5757:Polq	UTSW	16	36,907,043 (GRCm39)	missense	probably benign	0.01
R5764:Polq	UTSW	16	36,837,706 (GRCm39)	missense	probably damaging	0.97
R6019:Polq	UTSW	16	36,882,126 (GRCm39)	missense	probably damaging	1.00
R6170:Polq	UTSW	16	36,866,174 (GRCm39)	missense	possibly damaging	0.82
R6177:Polq	UTSW	16	36,892,071 (GRCm39)	missense	probably damaging	0.98
R6307:Polq	UTSW	16	36,837,718 (GRCm39)	critical splice donor site	probably null
R6499:Polq	UTSW	16	36,881,189 (GRCm39)	missense	probably benign	0.03
R6520:Polq	UTSW	16	36,880,739 (GRCm39)	missense	possibly damaging	0.88
R6598:Polq	UTSW	16	36,881,993 (GRCm39)	missense	probably benign	0.39
R6694:Polq	UTSW	16	36,835,535 (GRCm39)	missense	probably null	0.99
R6788:Polq	UTSW	16	36,897,510 (GRCm39)	missense	probably damaging	1.00
R7104:Polq	UTSW	16	36,909,715 (GRCm39)	nonsense	probably null
R7159:Polq	UTSW	16	36,883,215 (GRCm39)	missense	possibly damaging	0.87
R7222:Polq	UTSW	16	36,906,995 (GRCm39)	nonsense	probably null
R7340:Polq	UTSW	16	36,881,288 (GRCm39)	missense	probably benign	0.00
R7361:Polq	UTSW	16	36,880,790 (GRCm39)	missense	probably benign	0.00
R7384:Polq	UTSW	16	36,849,780 (GRCm39)	missense	probably damaging	1.00
R7509:Polq	UTSW	16	36,880,706 (GRCm39)	missense	probably benign	0.00
R7509:Polq	UTSW	16	36,880,705 (GRCm39)	missense	probably benign
R7575:Polq	UTSW	16	36,911,496 (GRCm39)	missense	probably benign	0.00
R7785:Polq	UTSW	16	36,848,239 (GRCm39)	missense	probably damaging	1.00
R7787:Polq	UTSW	16	36,837,671 (GRCm39)	missense	probably damaging	1.00
R7891:Polq	UTSW	16	36,848,244 (GRCm39)	missense	probably damaging	1.00
R7898:Polq	UTSW	16	36,865,245 (GRCm39)	missense	probably damaging	0.98
R7917:Polq	UTSW	16	36,885,650 (GRCm39)	missense	probably benign	0.08
R7940:Polq	UTSW	16	36,881,004 (GRCm39)	missense	probably benign	0.27
R8028:Polq	UTSW	16	36,881,678 (GRCm39)	missense	possibly damaging	0.82
R8114:Polq	UTSW	16	36,862,577 (GRCm39)	missense	possibly damaging	0.94
R8144:Polq	UTSW	16	36,849,846 (GRCm39)	missense	probably benign	0.01
R8288:Polq	UTSW	16	36,848,272 (GRCm39)	missense	probably damaging	1.00
R8301:Polq	UTSW	16	36,882,181 (GRCm39)	missense	probably damaging	1.00
R8341:Polq	UTSW	16	36,892,133 (GRCm39)	missense	possibly damaging	0.96
R8348:Polq	UTSW	16	36,837,559 (GRCm39)	critical splice acceptor site	probably null
R8448:Polq	UTSW	16	36,837,559 (GRCm39)	critical splice acceptor site	probably null
R8815:Polq	UTSW	16	36,853,893 (GRCm39)	missense	probably damaging	1.00
R8843:Polq	UTSW	16	36,832,280 (GRCm39)	missense	unknown
R8878:Polq	UTSW	16	36,860,869 (GRCm39)	missense	probably benign	0.02
R9016:Polq	UTSW	16	36,843,159 (GRCm39)	missense	probably damaging	1.00
R9189:Polq	UTSW	16	36,865,265 (GRCm39)	missense	probably damaging	1.00
R9209:Polq	UTSW	16	36,869,011 (GRCm39)	missense	possibly damaging	0.94
R9352:Polq	UTSW	16	36,862,252 (GRCm39)	missense	probably damaging	0.98
R9398:Polq	UTSW	16	36,881,394 (GRCm39)	missense	probably benign	0.02
R9403:Polq	UTSW	16	36,882,215 (GRCm39)	missense	probably benign	0.00
R9489:Polq	UTSW	16	36,843,173 (GRCm39)	missense	probably benign	0.00
R9605:Polq	UTSW	16	36,843,173 (GRCm39)	missense	probably benign	0.00
R9664:Polq	UTSW	16	36,848,176 (GRCm39)	missense	probably damaging	0.98
R9801:Polq	UTSW	16	36,913,190 (GRCm39)	missense	probably damaging	1.00
X0060:Polq	UTSW	16	36,837,599 (GRCm39)	nonsense	probably null
Z1176:Polq	UTSW	16	36,862,619 (GRCm39)	critical splice donor site	probably null

Predicted Primers

PCR Primer
(F):5'- ACAGCTTCTGTGGGTCCAAC -3'
(R):5'- CCAAATAATGACAGTAAGCTGCATG -3'

Sequencing Primer
(F):5'- GGTCCAACCCACTAATTATTTCTTTG -3'
(R):5'- GCTACTTGTCCTCAATAATTCCTGG -3'

Posted On

2014-12-04