Incidental Mutation 'R2519:Magi3'
| ID |
254157 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi3
|
| Ensembl Gene |
ENSMUSG00000052539 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Synonyms |
4732496O19Rik, 6530407C02Rik |
| MMRRC Submission |
040423-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.435)
|
| Stock # |
R2519 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
103920575-104127690 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 103923081 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1212
(E1212G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112934
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064371]
[ENSMUST00000121198]
[ENSMUST00000122303]
[ENSMUST00000145727]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064371
|
| SMART Domains |
Protein: ENSMUSP00000067932
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121198
AA Change: E1212G
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000112934
Gene: ENSMUSG00000052539
AA Change: E1212G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122303
|
| SMART Domains |
Protein: ENSMUSP00000113713
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145727
|
| SMART Domains |
Protein: ENSMUSP00000114722
Gene: ENSMUSG00000058388
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Phtf-FEM1B_bdg
|
3 |
158 |
1.6e-88 |
PFAM |
|
low complexity region
|
170 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
347 |
370 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
512 |
534 |
N/A |
INTRINSIC |
|
transmembrane domain
|
610 |
632 |
N/A |
INTRINSIC |
|
transmembrane domain
|
647 |
664 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0630 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
99% (72/73) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933408J17Rik |
G |
A |
10: 93,425,450 (GRCm39) |
|
probably benign |
Het |
| Abtb3 |
T |
A |
10: 85,487,475 (GRCm39) |
V981D |
probably damaging |
Het |
| Actn1 |
A |
T |
12: 80,239,163 (GRCm39) |
H247Q |
probably damaging |
Het |
| Adgre1 |
T |
C |
17: 57,717,956 (GRCm39) |
C323R |
probably damaging |
Het |
| Adgrf2 |
T |
A |
17: 43,021,298 (GRCm39) |
I509F |
probably damaging |
Het |
| Aknad1 |
A |
T |
3: 108,663,784 (GRCm39) |
T331S |
probably damaging |
Het |
| Aldh1a3 |
T |
C |
7: 66,072,047 (GRCm39) |
D39G |
probably benign |
Het |
| Alms1 |
C |
A |
6: 85,644,945 (GRCm39) |
|
probably benign |
Het |
| Ankhd1 |
T |
G |
18: 36,711,596 (GRCm39) |
|
probably null |
Het |
| Arfgef2 |
T |
C |
2: 166,723,164 (GRCm39) |
S1535P |
probably benign |
Het |
| Bicc1 |
T |
C |
10: 70,766,474 (GRCm39) |
E916G |
probably damaging |
Het |
| Birc2 |
A |
T |
9: 7,821,180 (GRCm39) |
D381E |
possibly damaging |
Het |
| Carnmt1 |
A |
G |
19: 18,671,075 (GRCm39) |
I316V |
probably benign |
Het |
| Cdk2ap1rt |
A |
G |
11: 48,716,950 (GRCm39) |
I76T |
probably damaging |
Het |
| Chd6 |
T |
A |
2: 160,871,796 (GRCm39) |
Y213F |
possibly damaging |
Het |
| Coq7 |
A |
T |
7: 118,109,371 (GRCm39) |
W226R |
unknown |
Het |
| Cyp2d9 |
G |
A |
15: 82,338,719 (GRCm39) |
|
probably null |
Het |
| Ddx42 |
T |
A |
11: 106,136,155 (GRCm39) |
N635K |
probably damaging |
Het |
| Dmtf1 |
T |
C |
5: 9,179,323 (GRCm39) |
T292A |
possibly damaging |
Het |
| Dnajb8 |
T |
C |
6: 88,199,857 (GRCm39) |
V131A |
probably benign |
Het |
| Dock6 |
T |
C |
9: 21,727,629 (GRCm39) |
E1367G |
possibly damaging |
Het |
| Dvl1 |
T |
A |
4: 155,940,000 (GRCm39) |
Y377* |
probably null |
Het |
| Eif4g3 |
T |
A |
4: 137,824,629 (GRCm39) |
F278Y |
probably benign |
Het |
| Fancg |
A |
T |
4: 43,008,787 (GRCm39) |
L150H |
probably damaging |
Het |
| Fastkd5 |
T |
C |
2: 130,458,114 (GRCm39) |
T159A |
possibly damaging |
Het |
| Fkrp |
G |
T |
7: 16,544,877 (GRCm39) |
Y328* |
probably null |
Het |
| Fmo3 |
A |
T |
1: 162,785,874 (GRCm39) |
V372D |
probably damaging |
Het |
| Gsta5 |
T |
G |
9: 78,211,721 (GRCm39) |
L161R |
probably damaging |
Het |
| Gtf2h4 |
C |
A |
17: 35,981,801 (GRCm39) |
G143W |
probably damaging |
Het |
| Hivep2 |
C |
A |
10: 14,004,713 (GRCm39) |
T437K |
probably benign |
Het |
| Hmcn1 |
A |
T |
1: 150,649,571 (GRCm39) |
Y638* |
probably null |
Het |
| Ighv11-2 |
T |
A |
12: 114,011,912 (GRCm39) |
Q101L |
probably damaging |
Het |
| Lgalsl2 |
A |
T |
7: 5,362,833 (GRCm39) |
I155F |
probably damaging |
Het |
| Lipf |
G |
T |
19: 33,942,925 (GRCm39) |
V78L |
probably damaging |
Het |
| Mfap5 |
T |
C |
6: 122,502,948 (GRCm39) |
S75P |
probably damaging |
Het |
| Mn1 |
C |
A |
5: 111,566,418 (GRCm39) |
H129Q |
possibly damaging |
Het |
| Morc3 |
A |
G |
16: 93,659,427 (GRCm39) |
|
probably null |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Myo5c |
A |
G |
9: 75,157,718 (GRCm39) |
I224V |
probably damaging |
Het |
| Nup58 |
T |
C |
14: 60,460,808 (GRCm39) |
T486A |
probably benign |
Het |
| Or5m13b |
A |
G |
2: 85,753,951 (GRCm39) |
Y113C |
probably damaging |
Het |
| Or8b46 |
T |
A |
9: 38,450,281 (GRCm39) |
V30D |
probably damaging |
Het |
| Parp14 |
A |
T |
16: 35,678,573 (GRCm39) |
L465Q |
possibly damaging |
Het |
| Pcare |
C |
T |
17: 72,058,642 (GRCm39) |
S345N |
probably damaging |
Het |
| Plcd3 |
A |
T |
11: 102,971,226 (GRCm39) |
I110N |
possibly damaging |
Het |
| Prx |
A |
G |
7: 27,217,668 (GRCm39) |
E862G |
probably benign |
Het |
| Rad50 |
G |
A |
11: 53,598,012 (GRCm39) |
|
probably benign |
Het |
| Rbm15 |
A |
G |
3: 107,238,149 (GRCm39) |
S750P |
probably benign |
Het |
| Reln |
C |
A |
5: 22,549,367 (GRCm39) |
A14S |
unknown |
Het |
| Rph3a |
T |
C |
5: 121,092,485 (GRCm39) |
Y372C |
probably damaging |
Het |
| Serpine2 |
T |
A |
1: 79,777,256 (GRCm39) |
H187L |
possibly damaging |
Het |
| Slc11a2 |
T |
C |
15: 100,299,204 (GRCm39) |
D122G |
probably damaging |
Het |
| Slc25a32 |
A |
T |
15: 38,959,450 (GRCm39) |
V289E |
probably damaging |
Het |
| Slc25a46 |
A |
T |
18: 31,735,814 (GRCm39) |
S142T |
probably benign |
Het |
| Srm |
A |
G |
4: 148,675,961 (GRCm39) |
|
probably null |
Het |
| Srsf5 |
A |
G |
12: 80,995,870 (GRCm39) |
D123G |
probably damaging |
Het |
| Stab1 |
A |
T |
14: 30,876,829 (GRCm39) |
C832S |
probably damaging |
Het |
| Stab2 |
A |
C |
10: 86,770,704 (GRCm39) |
|
probably benign |
Het |
| Suds3 |
T |
C |
5: 117,233,018 (GRCm39) |
N282S |
probably damaging |
Het |
| Taar9 |
A |
T |
10: 23,985,152 (GRCm39) |
V94E |
probably damaging |
Het |
| Taf2 |
C |
A |
15: 54,915,643 (GRCm39) |
A428S |
probably benign |
Het |
| Tbk1 |
G |
T |
10: 121,393,164 (GRCm39) |
T462K |
probably benign |
Het |
| Tcaf2 |
T |
G |
6: 42,606,365 (GRCm39) |
I530L |
possibly damaging |
Het |
| Tigd4 |
A |
G |
3: 84,501,221 (GRCm39) |
Y46C |
probably damaging |
Het |
| Topors |
G |
T |
4: 40,261,714 (GRCm39) |
Y523* |
probably null |
Het |
| Tpte |
T |
C |
8: 22,823,176 (GRCm39) |
|
probably benign |
Het |
| Trpv5 |
T |
A |
6: 41,651,284 (GRCm39) |
Q254L |
probably damaging |
Het |
| Trpv6 |
G |
A |
6: 41,601,550 (GRCm39) |
Q457* |
probably null |
Het |
| Ush2a |
A |
T |
1: 187,999,304 (GRCm39) |
M205L |
probably benign |
Het |
| Vmn1r90 |
A |
T |
7: 14,295,643 (GRCm39) |
Y152N |
probably damaging |
Het |
| Vmn2r124 |
T |
A |
17: 18,294,280 (GRCm39) |
V789D |
probably damaging |
Het |
| Vmn2r99 |
T |
C |
17: 19,598,970 (GRCm39) |
I218T |
probably damaging |
Het |
| Vstm2b |
T |
C |
7: 40,552,299 (GRCm39) |
V248A |
probably benign |
Het |
| Wnk2 |
T |
C |
13: 49,224,505 (GRCm39) |
K1019E |
probably damaging |
Het |
| Zfhx4 |
C |
T |
3: 5,468,418 (GRCm39) |
P2859S |
probably benign |
Het |
| Zfp229 |
T |
A |
17: 21,964,568 (GRCm39) |
F266Y |
possibly damaging |
Het |
| Zfp616 |
T |
A |
11: 73,975,094 (GRCm39) |
C454* |
probably null |
Het |
|
| Other mutations in Magi3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Magi3
|
APN |
3 |
103,922,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00933:Magi3
|
APN |
3 |
103,923,163 (GRCm39) |
missense |
probably benign |
|
|
IGL01151:Magi3
|
APN |
3 |
103,958,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01674:Magi3
|
APN |
3 |
104,013,037 (GRCm39) |
splice site |
probably benign |
|
|
IGL01790:Magi3
|
APN |
3 |
103,992,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01903:Magi3
|
APN |
3 |
103,958,526 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01939:Magi3
|
APN |
3 |
103,961,778 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02142:Magi3
|
APN |
3 |
103,923,219 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02183:Magi3
|
APN |
3 |
103,992,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02887:Magi3
|
APN |
3 |
104,002,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03071:Magi3
|
APN |
3 |
103,923,202 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03085:Magi3
|
APN |
3 |
103,922,655 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03192:Magi3
|
APN |
3 |
103,950,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Magi3
|
APN |
3 |
104,013,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03227:Magi3
|
APN |
3 |
103,958,435 (GRCm39) |
missense |
probably benign |
|
|
IGL03388:Magi3
|
APN |
3 |
103,923,157 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4280001:Magi3
|
UTSW |
3 |
103,961,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4504001:Magi3
|
UTSW |
3 |
103,922,842 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0092:Magi3
|
UTSW |
3 |
103,958,280 (GRCm39) |
nonsense |
probably null |
|
|
R0514:Magi3
|
UTSW |
3 |
103,922,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0569:Magi3
|
UTSW |
3 |
103,923,358 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0608:Magi3
|
UTSW |
3 |
103,924,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0920:Magi3
|
UTSW |
3 |
103,941,507 (GRCm39) |
splice site |
probably null |
|
|
R1173:Magi3
|
UTSW |
3 |
103,968,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1256:Magi3
|
UTSW |
3 |
103,935,126 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1391:Magi3
|
UTSW |
3 |
103,922,374 (GRCm39) |
nonsense |
probably null |
|
|
R1559:Magi3
|
UTSW |
3 |
103,954,169 (GRCm39) |
splice site |
probably benign |
|
|
R1568:Magi3
|
UTSW |
3 |
103,996,843 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1631:Magi3
|
UTSW |
3 |
103,958,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1747:Magi3
|
UTSW |
3 |
103,941,489 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1930:Magi3
|
UTSW |
3 |
103,996,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1964:Magi3
|
UTSW |
3 |
103,927,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2151:Magi3
|
UTSW |
3 |
103,992,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,954,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2267:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2268:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R3104:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3105:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3619:Magi3
|
UTSW |
3 |
103,961,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4158:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4160:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4284:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4285:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Magi3
|
UTSW |
3 |
104,127,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4512:Magi3
|
UTSW |
3 |
103,996,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Magi3
|
UTSW |
3 |
103,923,141 (GRCm39) |
missense |
probably benign |
|
|
R4758:Magi3
|
UTSW |
3 |
103,922,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4940:Magi3
|
UTSW |
3 |
103,958,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Magi3
|
UTSW |
3 |
104,013,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Magi3
|
UTSW |
3 |
103,935,224 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5422:Magi3
|
UTSW |
3 |
103,958,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Magi3
|
UTSW |
3 |
103,922,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5839:Magi3
|
UTSW |
3 |
104,127,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Magi3
|
UTSW |
3 |
103,961,854 (GRCm39) |
splice site |
probably null |
|
|
R6018:Magi3
|
UTSW |
3 |
104,013,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Magi3
|
UTSW |
3 |
103,958,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6235:Magi3
|
UTSW |
3 |
103,923,384 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6244:Magi3
|
UTSW |
3 |
103,923,013 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6258:Magi3
|
UTSW |
3 |
103,996,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6358:Magi3
|
UTSW |
3 |
103,958,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Magi3
|
UTSW |
3 |
103,992,536 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6806:Magi3
|
UTSW |
3 |
103,954,285 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6816:Magi3
|
UTSW |
3 |
103,997,227 (GRCm39) |
splice site |
probably null |
|
|
R6897:Magi3
|
UTSW |
3 |
103,996,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Magi3
|
UTSW |
3 |
104,013,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Magi3
|
UTSW |
3 |
103,958,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Magi3
|
UTSW |
3 |
103,956,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7237:Magi3
|
UTSW |
3 |
103,935,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7285:Magi3
|
UTSW |
3 |
103,941,430 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Magi3
|
UTSW |
3 |
103,941,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Magi3
|
UTSW |
3 |
103,923,243 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7797:Magi3
|
UTSW |
3 |
103,958,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Magi3
|
UTSW |
3 |
103,924,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8140:Magi3
|
UTSW |
3 |
103,941,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8204:Magi3
|
UTSW |
3 |
103,958,502 (GRCm39) |
missense |
probably benign |
|
|
R8229:Magi3
|
UTSW |
3 |
103,923,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8229:Magi3
|
UTSW |
3 |
103,923,017 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8260:Magi3
|
UTSW |
3 |
103,922,625 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8348:Magi3
|
UTSW |
3 |
103,958,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8368:Magi3
|
UTSW |
3 |
104,002,379 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8543:Magi3
|
UTSW |
3 |
104,126,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8762:Magi3
|
UTSW |
3 |
103,958,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Magi3
|
UTSW |
3 |
103,992,662 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8847:Magi3
|
UTSW |
3 |
103,922,334 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8892:Magi3
|
UTSW |
3 |
103,958,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Magi3
|
UTSW |
3 |
103,996,748 (GRCm39) |
intron |
probably benign |
|
|
R9090:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9187:Magi3
|
UTSW |
3 |
103,923,073 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9271:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9433:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9439:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9557:Magi3
|
UTSW |
3 |
103,924,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9557:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9697:Magi3
|
UTSW |
3 |
103,956,458 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9796:Magi3
|
UTSW |
3 |
103,928,291 (GRCm39) |
missense |
probably benign |
|
|
X0026:Magi3
|
UTSW |
3 |
103,927,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATGGTGAGCCGACCTTTAC -3'
(R):5'- TTCTGCTTCCACATTTGAAGAGTC -3'
Sequencing Primer
(F):5'- ATGGTGAGCCGACCTTTACTTTCTC -3'
(R):5'- CATTTGAAGAGTCTCATGTGCCAGC -3'
|
| Posted On |
2014-12-04 |
Incidental Mutation