Incidental Mutation 'R2519:Parp14'
| ID |
254260 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Parp14
|
| Ensembl Gene |
ENSMUSG00000034422 |
| Gene Name |
poly (ADP-ribose) polymerase family, member 14 |
| Synonyms |
CoaSt6, collaborator of Stat6, 1600029O10Rik |
| MMRRC Submission |
040423-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.493)
|
| Stock # |
R2519 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
35653244-35691914 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 35678573 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 465
(L465Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037657
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042665]
|
| AlphaFold |
Q2EMV9 |
| PDB Structure |
Solution structure of WWE domain in Parp14 protein [SOLUTION NMR]
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000042665
AA Change: L465Q
PolyPhen 2
Score 0.950 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000037657
Gene: ENSMUSG00000034422
AA Change: L465Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
38 |
49 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
115 |
N/A |
INTRINSIC |
|
RRM
|
228 |
297 |
4.71e-2 |
SMART |
|
coiled coil region
|
443 |
468 |
N/A |
INTRINSIC |
|
Blast:A1pp
|
693 |
746 |
6e-6 |
BLAST |
|
low complexity region
|
771 |
795 |
N/A |
INTRINSIC |
|
A1pp
|
814 |
948 |
7.62e-41 |
SMART |
|
A1pp
|
1026 |
1160 |
5.88e-24 |
SMART |
|
A1pp
|
1239 |
1358 |
6.82e-20 |
SMART |
|
PDB:1X4R|A
|
1532 |
1619 |
9e-53 |
PDB |
|
Pfam:PARP
|
1632 |
1817 |
2.5e-29 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142946
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
99% (72/73) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit altered B cell subsets and inability to respond to the apoptosis protective affects of IL4. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933408J17Rik |
G |
A |
10: 93,425,450 (GRCm39) |
|
probably benign |
Het |
| Abtb3 |
T |
A |
10: 85,487,475 (GRCm39) |
V981D |
probably damaging |
Het |
| Actn1 |
A |
T |
12: 80,239,163 (GRCm39) |
H247Q |
probably damaging |
Het |
| Adgre1 |
T |
C |
17: 57,717,956 (GRCm39) |
C323R |
probably damaging |
Het |
| Adgrf2 |
T |
A |
17: 43,021,298 (GRCm39) |
I509F |
probably damaging |
Het |
| Aknad1 |
A |
T |
3: 108,663,784 (GRCm39) |
T331S |
probably damaging |
Het |
| Aldh1a3 |
T |
C |
7: 66,072,047 (GRCm39) |
D39G |
probably benign |
Het |
| Alms1 |
C |
A |
6: 85,644,945 (GRCm39) |
|
probably benign |
Het |
| Ankhd1 |
T |
G |
18: 36,711,596 (GRCm39) |
|
probably null |
Het |
| Arfgef2 |
T |
C |
2: 166,723,164 (GRCm39) |
S1535P |
probably benign |
Het |
| Bicc1 |
T |
C |
10: 70,766,474 (GRCm39) |
E916G |
probably damaging |
Het |
| Birc2 |
A |
T |
9: 7,821,180 (GRCm39) |
D381E |
possibly damaging |
Het |
| Carnmt1 |
A |
G |
19: 18,671,075 (GRCm39) |
I316V |
probably benign |
Het |
| Cdk2ap1rt |
A |
G |
11: 48,716,950 (GRCm39) |
I76T |
probably damaging |
Het |
| Chd6 |
T |
A |
2: 160,871,796 (GRCm39) |
Y213F |
possibly damaging |
Het |
| Coq7 |
A |
T |
7: 118,109,371 (GRCm39) |
W226R |
unknown |
Het |
| Cyp2d9 |
G |
A |
15: 82,338,719 (GRCm39) |
|
probably null |
Het |
| Ddx42 |
T |
A |
11: 106,136,155 (GRCm39) |
N635K |
probably damaging |
Het |
| Dmtf1 |
T |
C |
5: 9,179,323 (GRCm39) |
T292A |
possibly damaging |
Het |
| Dnajb8 |
T |
C |
6: 88,199,857 (GRCm39) |
V131A |
probably benign |
Het |
| Dock6 |
T |
C |
9: 21,727,629 (GRCm39) |
E1367G |
possibly damaging |
Het |
| Dvl1 |
T |
A |
4: 155,940,000 (GRCm39) |
Y377* |
probably null |
Het |
| Eif4g3 |
T |
A |
4: 137,824,629 (GRCm39) |
F278Y |
probably benign |
Het |
| Fancg |
A |
T |
4: 43,008,787 (GRCm39) |
L150H |
probably damaging |
Het |
| Fastkd5 |
T |
C |
2: 130,458,114 (GRCm39) |
T159A |
possibly damaging |
Het |
| Fkrp |
G |
T |
7: 16,544,877 (GRCm39) |
Y328* |
probably null |
Het |
| Fmo3 |
A |
T |
1: 162,785,874 (GRCm39) |
V372D |
probably damaging |
Het |
| Gsta5 |
T |
G |
9: 78,211,721 (GRCm39) |
L161R |
probably damaging |
Het |
| Gtf2h4 |
C |
A |
17: 35,981,801 (GRCm39) |
G143W |
probably damaging |
Het |
| Hivep2 |
C |
A |
10: 14,004,713 (GRCm39) |
T437K |
probably benign |
Het |
| Hmcn1 |
A |
T |
1: 150,649,571 (GRCm39) |
Y638* |
probably null |
Het |
| Ighv11-2 |
T |
A |
12: 114,011,912 (GRCm39) |
Q101L |
probably damaging |
Het |
| Lgalsl2 |
A |
T |
7: 5,362,833 (GRCm39) |
I155F |
probably damaging |
Het |
| Lipf |
G |
T |
19: 33,942,925 (GRCm39) |
V78L |
probably damaging |
Het |
| Magi3 |
T |
C |
3: 103,923,081 (GRCm39) |
E1212G |
probably benign |
Het |
| Mfap5 |
T |
C |
6: 122,502,948 (GRCm39) |
S75P |
probably damaging |
Het |
| Mn1 |
C |
A |
5: 111,566,418 (GRCm39) |
H129Q |
possibly damaging |
Het |
| Morc3 |
A |
G |
16: 93,659,427 (GRCm39) |
|
probably null |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Myo5c |
A |
G |
9: 75,157,718 (GRCm39) |
I224V |
probably damaging |
Het |
| Nup58 |
T |
C |
14: 60,460,808 (GRCm39) |
T486A |
probably benign |
Het |
| Or5m13b |
A |
G |
2: 85,753,951 (GRCm39) |
Y113C |
probably damaging |
Het |
| Or8b46 |
T |
A |
9: 38,450,281 (GRCm39) |
V30D |
probably damaging |
Het |
| Pcare |
C |
T |
17: 72,058,642 (GRCm39) |
S345N |
probably damaging |
Het |
| Plcd3 |
A |
T |
11: 102,971,226 (GRCm39) |
I110N |
possibly damaging |
Het |
| Prx |
A |
G |
7: 27,217,668 (GRCm39) |
E862G |
probably benign |
Het |
| Rad50 |
G |
A |
11: 53,598,012 (GRCm39) |
|
probably benign |
Het |
| Rbm15 |
A |
G |
3: 107,238,149 (GRCm39) |
S750P |
probably benign |
Het |
| Reln |
C |
A |
5: 22,549,367 (GRCm39) |
A14S |
unknown |
Het |
| Rph3a |
T |
C |
5: 121,092,485 (GRCm39) |
Y372C |
probably damaging |
Het |
| Serpine2 |
T |
A |
1: 79,777,256 (GRCm39) |
H187L |
possibly damaging |
Het |
| Slc11a2 |
T |
C |
15: 100,299,204 (GRCm39) |
D122G |
probably damaging |
Het |
| Slc25a32 |
A |
T |
15: 38,959,450 (GRCm39) |
V289E |
probably damaging |
Het |
| Slc25a46 |
A |
T |
18: 31,735,814 (GRCm39) |
S142T |
probably benign |
Het |
| Srm |
A |
G |
4: 148,675,961 (GRCm39) |
|
probably null |
Het |
| Srsf5 |
A |
G |
12: 80,995,870 (GRCm39) |
D123G |
probably damaging |
Het |
| Stab1 |
A |
T |
14: 30,876,829 (GRCm39) |
C832S |
probably damaging |
Het |
| Stab2 |
A |
C |
10: 86,770,704 (GRCm39) |
|
probably benign |
Het |
| Suds3 |
T |
C |
5: 117,233,018 (GRCm39) |
N282S |
probably damaging |
Het |
| Taar9 |
A |
T |
10: 23,985,152 (GRCm39) |
V94E |
probably damaging |
Het |
| Taf2 |
C |
A |
15: 54,915,643 (GRCm39) |
A428S |
probably benign |
Het |
| Tbk1 |
G |
T |
10: 121,393,164 (GRCm39) |
T462K |
probably benign |
Het |
| Tcaf2 |
T |
G |
6: 42,606,365 (GRCm39) |
I530L |
possibly damaging |
Het |
| Tigd4 |
A |
G |
3: 84,501,221 (GRCm39) |
Y46C |
probably damaging |
Het |
| Topors |
G |
T |
4: 40,261,714 (GRCm39) |
Y523* |
probably null |
Het |
| Tpte |
T |
C |
8: 22,823,176 (GRCm39) |
|
probably benign |
Het |
| Trpv5 |
T |
A |
6: 41,651,284 (GRCm39) |
Q254L |
probably damaging |
Het |
| Trpv6 |
G |
A |
6: 41,601,550 (GRCm39) |
Q457* |
probably null |
Het |
| Ush2a |
A |
T |
1: 187,999,304 (GRCm39) |
M205L |
probably benign |
Het |
| Vmn1r90 |
A |
T |
7: 14,295,643 (GRCm39) |
Y152N |
probably damaging |
Het |
| Vmn2r124 |
T |
A |
17: 18,294,280 (GRCm39) |
V789D |
probably damaging |
Het |
| Vmn2r99 |
T |
C |
17: 19,598,970 (GRCm39) |
I218T |
probably damaging |
Het |
| Vstm2b |
T |
C |
7: 40,552,299 (GRCm39) |
V248A |
probably benign |
Het |
| Wnk2 |
T |
C |
13: 49,224,505 (GRCm39) |
K1019E |
probably damaging |
Het |
| Zfhx4 |
C |
T |
3: 5,468,418 (GRCm39) |
P2859S |
probably benign |
Het |
| Zfp229 |
T |
A |
17: 21,964,568 (GRCm39) |
F266Y |
possibly damaging |
Het |
| Zfp616 |
T |
A |
11: 73,975,094 (GRCm39) |
C454* |
probably null |
Het |
|
| Other mutations in Parp14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Parp14
|
APN |
16 |
35,661,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00497:Parp14
|
APN |
16 |
35,655,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00754:Parp14
|
APN |
16 |
35,659,741 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL00960:Parp14
|
APN |
16 |
35,661,589 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01321:Parp14
|
APN |
16 |
35,676,929 (GRCm39) |
missense |
probably benign |
|
|
IGL01397:Parp14
|
APN |
16 |
35,679,098 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01591:Parp14
|
APN |
16 |
35,678,877 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01728:Parp14
|
APN |
16 |
35,677,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01734:Parp14
|
APN |
16 |
35,678,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02156:Parp14
|
APN |
16 |
35,678,967 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02951:Parp14
|
APN |
16 |
35,678,903 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03067:Parp14
|
APN |
16 |
35,676,878 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03135:Parp14
|
APN |
16 |
35,678,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03141:Parp14
|
APN |
16 |
35,659,663 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03146:Parp14
|
APN |
16 |
35,678,823 (GRCm39) |
nonsense |
probably null |
|
|
IGL03333:Parp14
|
APN |
16 |
35,661,800 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03391:Parp14
|
APN |
16 |
35,678,640 (GRCm39) |
missense |
probably benign |
|
|
thurston
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
PIT4585001:Parp14
|
UTSW |
16 |
35,678,975 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0306:Parp14
|
UTSW |
16 |
35,676,944 (GRCm39) |
missense |
probably benign |
|
|
R0506:Parp14
|
UTSW |
16 |
35,661,779 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R0586:Parp14
|
UTSW |
16 |
35,661,382 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0606:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0612:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0699:Parp14
|
UTSW |
16 |
35,680,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0786:Parp14
|
UTSW |
16 |
35,661,172 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0883:Parp14
|
UTSW |
16 |
35,678,888 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0900:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1087:Parp14
|
UTSW |
16 |
35,678,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1104:Parp14
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
R1120:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1134:Parp14
|
UTSW |
16 |
35,655,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1153:Parp14
|
UTSW |
16 |
35,678,041 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1159:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1160:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1237:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1238:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1239:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1423:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1511:Parp14
|
UTSW |
16 |
35,677,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1518:Parp14
|
UTSW |
16 |
35,677,008 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1619:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1707:Parp14
|
UTSW |
16 |
35,678,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1792:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1831:Parp14
|
UTSW |
16 |
35,678,958 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1840:Parp14
|
UTSW |
16 |
35,683,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1902:Parp14
|
UTSW |
16 |
35,673,888 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1943:Parp14
|
UTSW |
16 |
35,656,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Parp14
|
UTSW |
16 |
35,678,671 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2115:Parp14
|
UTSW |
16 |
35,678,904 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2216:Parp14
|
UTSW |
16 |
35,677,575 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3851:Parp14
|
UTSW |
16 |
35,674,118 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4052:Parp14
|
UTSW |
16 |
35,678,771 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4671:Parp14
|
UTSW |
16 |
35,678,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4867:Parp14
|
UTSW |
16 |
35,677,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4941:Parp14
|
UTSW |
16 |
35,666,403 (GRCm39) |
missense |
probably benign |
|
|
R4992:Parp14
|
UTSW |
16 |
35,661,512 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5055:Parp14
|
UTSW |
16 |
35,664,733 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5073:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5170:Parp14
|
UTSW |
16 |
35,677,649 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5422:Parp14
|
UTSW |
16 |
35,686,545 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5543:Parp14
|
UTSW |
16 |
35,655,137 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5549:Parp14
|
UTSW |
16 |
35,661,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5553:Parp14
|
UTSW |
16 |
35,677,306 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5691:Parp14
|
UTSW |
16 |
35,683,909 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5774:Parp14
|
UTSW |
16 |
35,678,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5855:Parp14
|
UTSW |
16 |
35,661,297 (GRCm39) |
nonsense |
probably null |
|
|
R5942:Parp14
|
UTSW |
16 |
35,659,737 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5990:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5991:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6018:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6022:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6075:Parp14
|
UTSW |
16 |
35,677,389 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6395:Parp14
|
UTSW |
16 |
35,676,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6525:Parp14
|
UTSW |
16 |
35,680,811 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6683:Parp14
|
UTSW |
16 |
35,655,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7525:Parp14
|
UTSW |
16 |
35,677,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8011:Parp14
|
UTSW |
16 |
35,677,004 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8192:Parp14
|
UTSW |
16 |
35,691,584 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8367:Parp14
|
UTSW |
16 |
35,678,124 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8526:Parp14
|
UTSW |
16 |
35,661,307 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8751:Parp14
|
UTSW |
16 |
35,677,181 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8962:Parp14
|
UTSW |
16 |
35,677,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Parp14
|
UTSW |
16 |
35,661,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9363:Parp14
|
UTSW |
16 |
35,678,586 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9366:Parp14
|
UTSW |
16 |
35,659,630 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9379:Parp14
|
UTSW |
16 |
35,680,853 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9562:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9565:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,252 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,251 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0026:Parp14
|
UTSW |
16 |
35,677,527 (GRCm39) |
nonsense |
probably null |
|
|
X0060:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Parp14
|
UTSW |
16 |
35,661,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,665,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,691,573 (GRCm39) |
missense |
probably benign |
0.16 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATCCTTTTGAGCCATGGAGAAC -3'
(R):5'- GTTTGAAGTGTGCTCGCCAG -3'
Sequencing Primer
(F):5'- TTTGAGCCATGGAGAACACCTTC -3'
(R):5'- AAGTGTGCTCGCCAGTATGG -3'
|
| Posted On |
2014-12-04 |
Incidental Mutation