Incidental Mutation 'R2916:Anxa13'
ID256227
Institutional Source Beutler Lab
Gene Symbol Anxa13
Ensembl Gene ENSMUSG00000055114
Gene Nameannexin A13
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.126) question?
Stock #R2916 (G1)
Quality Score225
Status Not validated
Chromosome15
Chromosomal Location58341874-58364148 bp(-) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) T to C at 58345080 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000068515]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000068515
SMART Domains Protein: ENSMUSP00000065295
Gene: ENSMUSG00000055114

DomainStartEndE-ValueType
ANX 27 79 1.07e-23 SMART
ANX 99 151 8.37e-26 SMART
low complexity region 192 203 N/A INTRINSIC
ANX 250 302 1.65e-24 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000227274
Coding Region Coverage
  • 1x: 99.1%
  • 3x: 98.6%
  • 10x: 97.2%
  • 20x: 94.9%
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 18 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Brd7 A G 8: 88,342,780 I429T probably damaging Het
Btbd10 T C 7: 113,332,824 M124V probably benign Het
Dysf G A 6: 84,186,509 probably null Het
Ephb2 T C 4: 136,683,945 D468G probably damaging Het
Fig4 A G 10: 41,258,075 F404S probably damaging Het
Hcn3 A G 3: 89,147,613 S776P probably benign Het
Hivep2 C A 10: 14,128,969 T437K probably benign Het
Il17re G A 6: 113,466,028 probably null Het
Mug2 A G 6: 122,074,724 probably null Het
Nudt9 C A 5: 104,055,558 A121E probably damaging Het
Olfr223 T C 11: 59,589,439 T217A probably benign Het
Pdcd11 AGAGGAGGAGGAGGAGGAGGAGGAG AGAGGAGGAGGAGGAGGAGGAG 19: 47,113,437 probably benign Het
Pkdcc G C 17: 83,215,949 A162P probably benign Het
Rassf4 A G 6: 116,641,740 V194A probably damaging Het
Rps24 T C 14: 24,491,941 V23A probably benign Het
Six3 A T 17: 85,621,633 I132F probably benign Het
Srsf12 C T 4: 33,231,042 R179* probably null Het
Zbtb14 C T 17: 69,388,219 P304L probably damaging Het
Other mutations in Anxa13
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01417:Anxa13 APN 15 58356194 exon noncoding transcript
IGL02192:Anxa13 APN 15 58348780 exon noncoding transcript
IGL02654:Anxa13 APN 15 58342001 splice site noncoding transcript
R1572:Anxa13 UTSW 15 58348807 splice site noncoding transcript
R1973:Anxa13 UTSW 15 58356181 exon noncoding transcript
R1988:Anxa13 UTSW 15 58341948 exon noncoding transcript
R1989:Anxa13 UTSW 15 58341948 exon noncoding transcript
R4504:Anxa13 UTSW 15 58356203 exon noncoding transcript
R5832:Anxa13 UTSW 15 58341993 splice site noncoding transcript
R6526:Anxa13 UTSW 15 58344957 exon noncoding transcript
Predicted Primers
Posted On2014-12-31