Incidental Mutation 'R0325:Ddx60'
| ID |
25734 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| Synonyms |
|
| MMRRC Submission |
038535-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.145)
|
| Stock # |
R0325 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
61928087-62038244 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 61983855 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 946
(E946D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070631
AA Change: E945D
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
AA Change: E945D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093485
AA Change: E946D
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
AA Change: E946D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153806
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.9%
- 20x: 92.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931408C20Rik |
G |
T |
1: 26,685,266 (GRCm38) |
Q278K |
possibly damaging |
Het |
| 4933416C03Rik |
T |
C |
10: 116,113,569 (GRCm38) |
I17M |
probably damaging |
Het |
| 5330417C22Rik |
A |
G |
3: 108,461,251 (GRCm38) |
L808P |
probably damaging |
Het |
| Adcyap1 |
A |
G |
17: 93,202,832 (GRCm38) |
D96G |
probably benign |
Het |
| Adgrv1 |
C |
T |
13: 81,540,015 (GRCm38) |
V1749M |
probably damaging |
Het |
| Adnp2 |
A |
T |
18: 80,130,653 (GRCm38) |
N180K |
probably benign |
Het |
| Ahdc1 |
G |
T |
4: 133,062,719 (GRCm38) |
A424S |
unknown |
Het |
| Alpk3 |
G |
A |
7: 81,067,953 (GRCm38) |
R86H |
possibly damaging |
Het |
| Atf7ip |
A |
C |
6: 136,560,989 (GRCm38) |
T49P |
possibly damaging |
Het |
| Atp7b |
G |
A |
8: 22,028,451 (GRCm38) |
L124F |
probably benign |
Het |
| Bub1 |
A |
T |
2: 127,801,394 (GRCm38) |
L1010* |
probably null |
Het |
| Cd300c |
C |
A |
11: 114,959,585 (GRCm38) |
E131* |
probably null |
Het |
| Cep135 |
A |
G |
5: 76,615,743 (GRCm38) |
K527E |
probably damaging |
Het |
| Cfd |
G |
T |
10: 79,891,758 (GRCm38) |
E89* |
probably null |
Het |
| Crb1 |
A |
C |
1: 139,241,166 (GRCm38) |
C871W |
probably damaging |
Het |
| D6Ertd527e |
A |
T |
6: 87,111,295 (GRCm38) |
S147C |
unknown |
Het |
| Dmrt1 |
G |
A |
19: 25,546,007 (GRCm38) |
E241K |
probably benign |
Het |
| Dnah11 |
C |
G |
12: 118,012,339 (GRCm38) |
V2782L |
probably benign |
Het |
| Dzip1 |
T |
C |
14: 118,909,557 (GRCm38) |
I313M |
probably damaging |
Het |
| Egln3 |
T |
C |
12: 54,203,512 (GRCm38) |
E17G |
probably benign |
Het |
| Eif3d |
A |
G |
15: 77,968,220 (GRCm38) |
V42A |
probably damaging |
Het |
| Eogt |
C |
A |
6: 97,113,955 (GRCm38) |
G408W |
probably damaging |
Het |
| Fip1l1 |
T |
A |
5: 74,595,842 (GRCm38) |
N498K |
probably damaging |
Het |
| Fmn2 |
T |
A |
1: 174,609,954 (GRCm38) |
|
probably null |
Het |
| Fndc3b |
T |
C |
3: 27,467,430 (GRCm38) |
E532G |
probably damaging |
Het |
| Gabrb3 |
T |
C |
7: 57,765,530 (GRCm38) |
L116P |
probably damaging |
Het |
| Galnt6 |
A |
T |
15: 100,693,471 (GRCm38) |
|
probably null |
Het |
| Glmp |
G |
A |
3: 88,325,084 (GRCm38) |
M1I |
probably null |
Het |
| Gm13101 |
A |
T |
4: 143,966,740 (GRCm38) |
V56E |
probably damaging |
Het |
| Gm13124 |
T |
C |
4: 144,555,511 (GRCm38) |
Y237C |
probably damaging |
Het |
| Gm5478 |
T |
C |
15: 101,644,326 (GRCm38) |
D79G |
probably damaging |
Het |
| Gnb1 |
T |
G |
4: 155,551,683 (GRCm38) |
D153E |
probably benign |
Het |
| Grik2 |
T |
C |
10: 49,240,725 (GRCm38) |
I86V |
probably damaging |
Het |
| Hdac3 |
C |
T |
18: 37,940,952 (GRCm38) |
|
probably null |
Het |
| Hdgfl2 |
G |
A |
17: 56,099,181 (GRCm38) |
R523H |
possibly damaging |
Het |
| Ifngr1 |
T |
A |
10: 19,597,432 (GRCm38) |
N43K |
probably damaging |
Het |
| Iqgap1 |
A |
G |
7: 80,751,930 (GRCm38) |
W476R |
probably benign |
Het |
| Jag1 |
A |
G |
2: 137,095,445 (GRCm38) |
|
probably null |
Het |
| Kars |
T |
C |
8: 112,008,216 (GRCm38) |
D46G |
probably benign |
Het |
| Kcnd2 |
A |
G |
6: 21,216,683 (GRCm38) |
I129V |
probably damaging |
Het |
| Lama3 |
A |
C |
18: 12,482,126 (GRCm38) |
D1369A |
probably damaging |
Het |
| Lars |
A |
T |
18: 42,250,902 (GRCm38) |
V76E |
possibly damaging |
Het |
| Lgals9 |
T |
C |
11: 78,963,448 (GRCm38) |
I337V |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 40,851,711 (GRCm38) |
D3068G |
probably damaging |
Het |
| Med12l |
A |
G |
3: 59,077,059 (GRCm38) |
T462A |
possibly damaging |
Het |
| Megf9 |
T |
A |
4: 70,455,941 (GRCm38) |
D286V |
probably damaging |
Het |
| Meox1 |
T |
A |
11: 101,879,401 (GRCm38) |
S167C |
probably damaging |
Het |
| Mier2 |
C |
T |
10: 79,542,596 (GRCm38) |
|
probably null |
Het |
| Mrps2 |
C |
A |
2: 28,469,779 (GRCm38) |
T216K |
probably damaging |
Het |
| Mto1 |
A |
T |
9: 78,453,004 (GRCm38) |
D258V |
probably damaging |
Het |
| Mug1 |
A |
T |
6: 121,849,842 (GRCm38) |
H208L |
probably benign |
Het |
| Myo15b |
T |
A |
11: 115,884,265 (GRCm38) |
I751N |
probably damaging |
Het |
| Napg |
C |
T |
18: 62,986,963 (GRCm38) |
R149C |
probably damaging |
Het |
| Ndrg4 |
T |
A |
8: 95,710,935 (GRCm38) |
M17K |
probably damaging |
Het |
| Nfrkb |
T |
G |
9: 31,414,180 (GRCm38) |
M973R |
probably benign |
Het |
| Nxph4 |
C |
T |
10: 127,526,911 (GRCm38) |
R37H |
probably damaging |
Het |
| Oas1e |
A |
G |
5: 120,795,395 (GRCm38) |
I35T |
probably damaging |
Het |
| Oc90 |
C |
T |
15: 65,897,665 (GRCm38) |
|
probably null |
Het |
| Olfr1045 |
G |
A |
2: 86,198,711 (GRCm38) |
L14F |
possibly damaging |
Het |
| Olfr1076 |
A |
T |
2: 86,509,205 (GRCm38) |
T249S |
probably benign |
Het |
| Olfr1271 |
A |
T |
2: 90,265,536 (GRCm38) |
M298K |
probably null |
Het |
| Olfr461 |
A |
T |
6: 40,544,123 (GRCm38) |
N285K |
possibly damaging |
Het |
| Olfr653 |
A |
T |
7: 104,580,360 (GRCm38) |
D238V |
probably damaging |
Het |
| Papola |
T |
A |
12: 105,807,193 (GRCm38) |
I157N |
probably damaging |
Het |
| Pcyox1l |
G |
C |
18: 61,697,893 (GRCm38) |
P303A |
possibly damaging |
Het |
| Pkdrej |
T |
C |
15: 85,819,551 (GRCm38) |
N728S |
probably benign |
Het |
| Pkp4 |
A |
G |
2: 59,318,529 (GRCm38) |
D542G |
probably damaging |
Het |
| Pla2g5 |
C |
T |
4: 138,800,656 (GRCm38) |
D100N |
probably benign |
Het |
| Poln |
C |
T |
5: 34,149,764 (GRCm38) |
R31H |
probably benign |
Het |
| Ppp3ca |
G |
A |
3: 136,935,139 (GRCm38) |
A484T |
probably benign |
Het |
| Prag1 |
A |
G |
8: 36,103,804 (GRCm38) |
T514A |
probably benign |
Het |
| Prex2 |
G |
A |
1: 11,200,057 (GRCm38) |
|
probably null |
Het |
| Prrc2b |
G |
T |
2: 32,199,091 (GRCm38) |
W403L |
probably damaging |
Het |
| Pter |
A |
T |
2: 13,000,937 (GRCm38) |
K307M |
probably damaging |
Het |
| Ptpn5 |
G |
A |
7: 47,090,758 (GRCm38) |
S99L |
probably benign |
Het |
| Ptpn5 |
A |
C |
7: 47,090,759 (GRCm38) |
S99A |
probably benign |
Het |
| Rpap1 |
A |
C |
2: 119,771,840 (GRCm38) |
H674Q |
probably benign |
Het |
| Rph3a |
A |
T |
5: 120,943,064 (GRCm38) |
D623E |
probably benign |
Het |
| Sdr9c7 |
G |
T |
10: 127,898,719 (GRCm38) |
E25D |
probably benign |
Het |
| Sept9 |
T |
G |
11: 117,356,632 (GRCm38) |
V479G |
probably damaging |
Het |
| Sgo2a |
A |
G |
1: 58,016,697 (GRCm38) |
D680G |
probably benign |
Het |
| Sgo2b |
A |
T |
8: 63,928,376 (GRCm38) |
I474N |
probably benign |
Het |
| Sgsm1 |
A |
T |
5: 113,288,835 (GRCm38) |
I43N |
probably damaging |
Het |
| Shprh |
G |
A |
10: 11,170,109 (GRCm38) |
M891I |
probably benign |
Het |
| Skiv2l |
A |
T |
17: 34,844,815 (GRCm38) |
Y551N |
possibly damaging |
Het |
| Slc12a9 |
A |
G |
5: 137,322,846 (GRCm38) |
M469T |
probably damaging |
Het |
| Slc4a2 |
A |
T |
5: 24,435,943 (GRCm38) |
I747F |
probably damaging |
Het |
| Slc7a6 |
T |
A |
8: 106,194,517 (GRCm38) |
N373K |
probably damaging |
Het |
| Slc7a6os |
T |
C |
8: 106,201,056 (GRCm38) |
D296G |
probably benign |
Het |
| Sncaip |
A |
G |
18: 52,905,809 (GRCm38) |
T120A |
probably damaging |
Het |
| Sorcs1 |
G |
C |
19: 50,313,042 (GRCm38) |
|
probably null |
Het |
| Spata16 |
A |
G |
3: 26,667,456 (GRCm38) |
E42G |
probably damaging |
Het |
| Syne2 |
A |
T |
12: 75,962,641 (GRCm38) |
M2440L |
probably benign |
Het |
| Tead2 |
A |
G |
7: 45,225,755 (GRCm38) |
E232G |
probably damaging |
Het |
| Tmf1 |
T |
G |
6: 97,176,504 (GRCm38) |
T203P |
possibly damaging |
Het |
| Trrap |
C |
A |
5: 144,816,395 (GRCm38) |
H1843Q |
probably benign |
Het |
| Unc79 |
C |
A |
12: 103,171,644 (GRCm38) |
Q2314K |
probably damaging |
Het |
| Unc80 |
G |
T |
1: 66,510,881 (GRCm38) |
G766V |
probably damaging |
Het |
| Vmn1r217 |
A |
G |
13: 23,114,594 (GRCm38) |
L46P |
probably damaging |
Het |
| Vmn2r80 |
A |
T |
10: 79,148,939 (GRCm38) |
I42F |
possibly damaging |
Het |
| Vwa5a |
T |
C |
9: 38,728,665 (GRCm38) |
V403A |
probably damaging |
Het |
| Zfp42 |
T |
C |
8: 43,295,951 (GRCm38) |
E171G |
probably damaging |
Het |
| Zfp64 |
A |
T |
2: 168,926,040 (GRCm38) |
S551T |
probably benign |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
61,958,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
61,987,431 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
61,969,583 (GRCm38) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
61,942,514 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
61,982,526 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
61,963,740 (GRCm38) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
61,983,865 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,017,823 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,000,709 (GRCm38) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,017,247 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
61,975,832 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
61,958,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,024,951 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
61,942,436 (GRCm38) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
61,984,115 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
61,988,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
61,979,341 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
61,956,122 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
61,988,083 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,012,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
61,977,882 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
61,958,113 (GRCm38) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
61,972,254 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
61,942,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,033,493 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0367:Ddx60
|
UTSW |
8 |
62,017,749 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R0403:Ddx60
|
UTSW |
8 |
61,994,541 (GRCm38) |
splice site |
probably benign |
|
|
R0479:Ddx60
|
UTSW |
8 |
61,969,657 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,017,794 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
61,987,361 (GRCm38) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
61,942,544 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
61,958,159 (GRCm38) |
splice site |
probably benign |
|
|
R1778:Ddx60
|
UTSW |
8 |
61,974,176 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1840:Ddx60
|
UTSW |
8 |
61,969,553 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1964:Ddx60
|
UTSW |
8 |
61,948,869 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1970:Ddx60
|
UTSW |
8 |
61,972,206 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R2101:Ddx60
|
UTSW |
8 |
61,940,645 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,017,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
61,956,141 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
61,958,063 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,037,091 (GRCm38) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,012,436 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,037,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
61,956,144 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
61,972,220 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
61,994,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
61,948,978 (GRCm38) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
61,942,461 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
61,987,421 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,023,261 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,012,424 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
61,945,906 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
61,974,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
61,984,158 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,010,002 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
61,950,451 (GRCm38) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
61,958,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,000,578 (GRCm38) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
61,948,921 (GRCm38) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
61,948,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,012,388 (GRCm38) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
61,963,722 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
61,940,740 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,021,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,000,582 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,023,241 (GRCm38) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
61,945,940 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
61,950,578 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
61,983,905 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
61,998,681 (GRCm38) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
61,977,950 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
61,956,239 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
61,983,890 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,000,689 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,037,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
61,988,108 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
61,958,578 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
61,940,674 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
61,975,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
61,977,890 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,017,171 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,017,250 (GRCm38) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
61,977,968 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
61,998,769 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
61,942,635 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
61,974,171 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
61,956,243 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
61,974,150 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
61,958,606 (GRCm38) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
61,945,956 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
61,940,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
61,994,519 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
61,974,134 (GRCm38) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
61,989,864 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,017,841 (GRCm38) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
61,977,978 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,009,960 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
61,972,214 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,012,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,033,417 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
61,963,692 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,000,588 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCATCCCTGGAAGTGGGATTGAAGG -3'
(R):5'- ACGTGATCTATGGTTAGTGCAGCG -3'
Sequencing Primer
(F):5'- ggaagtgggattgaagggaaag -3'
(R):5'- TCTCCATAGAGCACTGGAGGG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation