Incidental Mutation 'R0325:Myo15b'
| ID |
25766 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo15b
|
| Ensembl Gene |
ENSMUSG00000034427 |
| Gene Name |
myosin XVB |
| Synonyms |
LOC217328, LOC380737, E330039G21Rik |
| MMRRC Submission |
038535-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.063)
|
| Stock # |
R0325 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
115749232-115783429 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 115775091 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 751
(I751N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000152405
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040703]
[ENSMUST00000093911]
[ENSMUST00000125835]
[ENSMUST00000167507]
[ENSMUST00000222123]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000040703
AA Change: I519N
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000048072
Gene: ENSMUSG00000034427
AA Change: I519N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
93 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
179 |
213 |
N/A |
INTRINSIC |
|
low complexity region
|
250 |
289 |
N/A |
INTRINSIC |
|
low complexity region
|
345 |
370 |
N/A |
INTRINSIC |
|
low complexity region
|
497 |
511 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
552 |
N/A |
INTRINSIC |
|
Blast:MYSc
|
587 |
775 |
3e-15 |
BLAST |
|
SH3
|
778 |
835 |
1.15e-7 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000093911
AA Change: I2173N
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000091439
Gene: ENSMUSG00000034427
AA Change: I2173N
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
1 |
640 |
2.4e-134 |
SMART |
|
IQ
|
660 |
682 |
1.03e1 |
SMART |
|
Pfam:MyTH4
|
837 |
945 |
2.1e-23 |
PFAM |
|
low complexity region
|
1050 |
1068 |
N/A |
INTRINSIC |
|
low complexity region
|
1136 |
1170 |
N/A |
INTRINSIC |
|
low complexity region
|
1207 |
1246 |
N/A |
INTRINSIC |
|
low complexity region
|
1302 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1468 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1509 |
N/A |
INTRINSIC |
|
SH3
|
1735 |
1792 |
1.15e-7 |
SMART |
|
Pfam:MyTH4
|
1928 |
2029 |
8.3e-25 |
PFAM |
|
B41
|
2032 |
2235 |
6.99e-4 |
SMART |
|
low complexity region
|
2243 |
2253 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125835
|
| SMART Domains |
Protein: ENSMUSP00000144423
Gene: ENSMUSG00000034427
| Domain | Start | End | E-Value | Type |
|---|
|
SH3
|
75 |
132 |
7e-10 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132447
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151507
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167507
|
| SMART Domains |
Protein: ENSMUSP00000129226
Gene: ENSMUSG00000034427
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:MyTH4
|
100 |
205 |
3.1e-24 |
PFAM |
|
B41
|
207 |
410 |
6.99e-4 |
SMART |
|
low complexity region
|
418 |
428 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000222123
AA Change: I751N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.9%
- 20x: 92.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm2 |
T |
C |
4: 144,282,081 (GRCm39) |
Y237C |
probably damaging |
Het |
| Adcyap1 |
A |
G |
17: 93,510,260 (GRCm39) |
D96G |
probably benign |
Het |
| Adgrv1 |
C |
T |
13: 81,688,134 (GRCm39) |
V1749M |
probably damaging |
Het |
| Adnp2 |
A |
T |
18: 80,173,868 (GRCm39) |
N180K |
probably benign |
Het |
| Ahdc1 |
G |
T |
4: 132,790,030 (GRCm39) |
A424S |
unknown |
Het |
| Alpk3 |
G |
A |
7: 80,717,701 (GRCm39) |
R86H |
possibly damaging |
Het |
| Atf7ip |
A |
C |
6: 136,537,987 (GRCm39) |
T49P |
possibly damaging |
Het |
| Atp7b |
G |
A |
8: 22,518,467 (GRCm39) |
L124F |
probably benign |
Het |
| Bub1 |
A |
T |
2: 127,643,314 (GRCm39) |
L1010* |
probably null |
Het |
| Cd300c |
C |
A |
11: 114,850,411 (GRCm39) |
E131* |
probably null |
Het |
| Cep135 |
A |
G |
5: 76,763,590 (GRCm39) |
K527E |
probably damaging |
Het |
| Cfd |
G |
T |
10: 79,727,592 (GRCm39) |
E89* |
probably null |
Het |
| Crb1 |
A |
C |
1: 139,168,904 (GRCm39) |
C871W |
probably damaging |
Het |
| D6Ertd527e |
A |
T |
6: 87,088,277 (GRCm39) |
S147C |
unknown |
Het |
| Ddx60 |
A |
T |
8: 62,436,889 (GRCm39) |
E946D |
probably benign |
Het |
| Dmrt1 |
G |
A |
19: 25,523,371 (GRCm39) |
E241K |
probably benign |
Het |
| Dnah11 |
C |
G |
12: 117,976,074 (GRCm39) |
V2782L |
probably benign |
Het |
| Dzip1 |
T |
C |
14: 119,146,969 (GRCm39) |
I313M |
probably damaging |
Het |
| Egln3 |
T |
C |
12: 54,250,298 (GRCm39) |
E17G |
probably benign |
Het |
| Eif3d |
A |
G |
15: 77,852,420 (GRCm39) |
V42A |
probably damaging |
Het |
| Elapor1 |
A |
G |
3: 108,368,567 (GRCm39) |
L808P |
probably damaging |
Het |
| Eogt |
C |
A |
6: 97,090,916 (GRCm39) |
G408W |
probably damaging |
Het |
| Fip1l1 |
T |
A |
5: 74,756,503 (GRCm39) |
N498K |
probably damaging |
Het |
| Fmn2 |
T |
A |
1: 174,437,520 (GRCm39) |
|
probably null |
Het |
| Fndc3b |
T |
C |
3: 27,521,579 (GRCm39) |
E532G |
probably damaging |
Het |
| Gabrb3 |
T |
C |
7: 57,415,278 (GRCm39) |
L116P |
probably damaging |
Het |
| Galnt6 |
A |
T |
15: 100,591,352 (GRCm39) |
|
probably null |
Het |
| Glmp |
G |
A |
3: 88,232,391 (GRCm39) |
M1I |
probably null |
Het |
| Gm5478 |
T |
C |
15: 101,552,761 (GRCm39) |
D79G |
probably damaging |
Het |
| Gnb1 |
T |
G |
4: 155,636,140 (GRCm39) |
D153E |
probably benign |
Het |
| Grik2 |
T |
C |
10: 49,116,821 (GRCm39) |
I86V |
probably damaging |
Het |
| Hdac3 |
C |
T |
18: 38,074,005 (GRCm39) |
|
probably null |
Het |
| Hdgfl2 |
G |
A |
17: 56,406,181 (GRCm39) |
R523H |
possibly damaging |
Het |
| Ifngr1 |
T |
A |
10: 19,473,180 (GRCm39) |
N43K |
probably damaging |
Het |
| Iqgap1 |
A |
G |
7: 80,401,678 (GRCm39) |
W476R |
probably benign |
Het |
| Jag1 |
A |
G |
2: 136,937,365 (GRCm39) |
|
probably null |
Het |
| Kars1 |
T |
C |
8: 112,734,848 (GRCm39) |
D46G |
probably benign |
Het |
| Kcnd2 |
A |
G |
6: 21,216,682 (GRCm39) |
I129V |
probably damaging |
Het |
| Lama3 |
A |
C |
18: 12,615,183 (GRCm39) |
D1369A |
probably damaging |
Het |
| Lars1 |
A |
T |
18: 42,383,967 (GRCm39) |
V76E |
possibly damaging |
Het |
| Lgals9 |
T |
C |
11: 78,854,274 (GRCm39) |
I337V |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 40,741,723 (GRCm39) |
D3068G |
probably damaging |
Het |
| Med12l |
A |
G |
3: 58,984,480 (GRCm39) |
T462A |
possibly damaging |
Het |
| Megf9 |
T |
A |
4: 70,374,178 (GRCm39) |
D286V |
probably damaging |
Het |
| Meox1 |
T |
A |
11: 101,770,227 (GRCm39) |
S167C |
probably damaging |
Het |
| Mier2 |
C |
T |
10: 79,378,430 (GRCm39) |
|
probably null |
Het |
| Mrps2 |
C |
A |
2: 28,359,791 (GRCm39) |
T216K |
probably damaging |
Het |
| Mto1 |
A |
T |
9: 78,360,286 (GRCm39) |
D258V |
probably damaging |
Het |
| Mug1 |
A |
T |
6: 121,826,801 (GRCm39) |
H208L |
probably benign |
Het |
| Napg |
C |
T |
18: 63,120,034 (GRCm39) |
R149C |
probably damaging |
Het |
| Ndrg4 |
T |
A |
8: 96,437,563 (GRCm39) |
M17K |
probably damaging |
Het |
| Nfrkb |
T |
G |
9: 31,325,476 (GRCm39) |
M973R |
probably benign |
Het |
| Nxph4 |
C |
T |
10: 127,362,780 (GRCm39) |
R37H |
probably damaging |
Het |
| Oas1e |
A |
G |
5: 120,933,460 (GRCm39) |
I35T |
probably damaging |
Het |
| Oc90 |
C |
T |
15: 65,769,514 (GRCm39) |
|
probably null |
Het |
| Or4b12 |
A |
T |
2: 90,095,880 (GRCm39) |
M298K |
probably null |
Het |
| Or52d3 |
A |
T |
7: 104,229,567 (GRCm39) |
D238V |
probably damaging |
Het |
| Or8j3 |
G |
A |
2: 86,029,055 (GRCm39) |
L14F |
possibly damaging |
Het |
| Or8k30 |
A |
T |
2: 86,339,549 (GRCm39) |
T249S |
probably benign |
Het |
| Or9a7 |
A |
T |
6: 40,521,057 (GRCm39) |
N285K |
possibly damaging |
Het |
| Papola |
T |
A |
12: 105,773,452 (GRCm39) |
I157N |
probably damaging |
Het |
| Pcyox1l |
G |
C |
18: 61,830,964 (GRCm39) |
P303A |
possibly damaging |
Het |
| Pkdrej |
T |
C |
15: 85,703,752 (GRCm39) |
N728S |
probably benign |
Het |
| Pkp4 |
A |
G |
2: 59,148,873 (GRCm39) |
D542G |
probably damaging |
Het |
| Pla2g5 |
C |
T |
4: 138,527,967 (GRCm39) |
D100N |
probably benign |
Het |
| Poln |
C |
T |
5: 34,307,108 (GRCm39) |
R31H |
probably benign |
Het |
| Ppp3ca |
G |
A |
3: 136,640,900 (GRCm39) |
A484T |
probably benign |
Het |
| Prag1 |
A |
G |
8: 36,570,958 (GRCm39) |
T514A |
probably benign |
Het |
| Pramel28 |
A |
T |
4: 143,693,310 (GRCm39) |
V56E |
probably damaging |
Het |
| Prex2 |
G |
A |
1: 11,270,281 (GRCm39) |
|
probably null |
Het |
| Prrc2b |
G |
T |
2: 32,089,103 (GRCm39) |
W403L |
probably damaging |
Het |
| Pter |
A |
T |
2: 13,005,748 (GRCm39) |
K307M |
probably damaging |
Het |
| Ptpn5 |
G |
A |
7: 46,740,506 (GRCm39) |
S99L |
probably benign |
Het |
| Ptpn5 |
A |
C |
7: 46,740,507 (GRCm39) |
S99A |
probably benign |
Het |
| Rpap1 |
A |
C |
2: 119,602,321 (GRCm39) |
H674Q |
probably benign |
Het |
| Rph3a |
A |
T |
5: 121,081,127 (GRCm39) |
D623E |
probably benign |
Het |
| Sdr9c7 |
G |
T |
10: 127,734,588 (GRCm39) |
E25D |
probably benign |
Het |
| Septin9 |
T |
G |
11: 117,247,458 (GRCm39) |
V479G |
probably damaging |
Het |
| Sgo2a |
A |
G |
1: 58,055,856 (GRCm39) |
D680G |
probably benign |
Het |
| Sgo2b |
A |
T |
8: 64,381,410 (GRCm39) |
I474N |
probably benign |
Het |
| Sgsm1 |
A |
T |
5: 113,436,701 (GRCm39) |
I43N |
probably damaging |
Het |
| Shprh |
G |
A |
10: 11,045,853 (GRCm39) |
M891I |
probably benign |
Het |
| Skic2 |
A |
T |
17: 35,063,791 (GRCm39) |
Y551N |
possibly damaging |
Het |
| Slc12a9 |
A |
G |
5: 137,321,108 (GRCm39) |
M469T |
probably damaging |
Het |
| Slc4a2 |
A |
T |
5: 24,640,941 (GRCm39) |
I747F |
probably damaging |
Het |
| Slc7a6 |
T |
A |
8: 106,921,149 (GRCm39) |
N373K |
probably damaging |
Het |
| Slc7a6os |
T |
C |
8: 106,927,688 (GRCm39) |
D296G |
probably benign |
Het |
| Sncaip |
A |
G |
18: 53,038,881 (GRCm39) |
T120A |
probably damaging |
Het |
| Sorcs1 |
G |
C |
19: 50,301,480 (GRCm39) |
|
probably null |
Het |
| Spata16 |
A |
G |
3: 26,721,605 (GRCm39) |
E42G |
probably damaging |
Het |
| Spata31e2 |
G |
T |
1: 26,724,347 (GRCm39) |
Q278K |
possibly damaging |
Het |
| Syne2 |
A |
T |
12: 76,009,415 (GRCm39) |
M2440L |
probably benign |
Het |
| Taf7l2 |
T |
C |
10: 115,949,474 (GRCm39) |
I17M |
probably damaging |
Het |
| Tead2 |
A |
G |
7: 44,875,179 (GRCm39) |
E232G |
probably damaging |
Het |
| Tmf1 |
T |
G |
6: 97,153,465 (GRCm39) |
T203P |
possibly damaging |
Het |
| Trrap |
C |
A |
5: 144,753,205 (GRCm39) |
H1843Q |
probably benign |
Het |
| Unc79 |
C |
A |
12: 103,137,903 (GRCm39) |
Q2314K |
probably damaging |
Het |
| Unc80 |
G |
T |
1: 66,550,040 (GRCm39) |
G766V |
probably damaging |
Het |
| Vmn1r217 |
A |
G |
13: 23,298,764 (GRCm39) |
L46P |
probably damaging |
Het |
| Vmn2r80 |
A |
T |
10: 78,984,773 (GRCm39) |
I42F |
possibly damaging |
Het |
| Vwa5a |
T |
C |
9: 38,639,961 (GRCm39) |
V403A |
probably damaging |
Het |
| Zfp42 |
T |
C |
8: 43,748,988 (GRCm39) |
E171G |
probably damaging |
Het |
| Zfp64 |
A |
T |
2: 168,767,960 (GRCm39) |
S551T |
probably benign |
Het |
|
| Other mutations in Myo15b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00556:Myo15b
|
APN |
11 |
115,782,742 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01409:Myo15b
|
APN |
11 |
115,760,330 (GRCm39) |
nonsense |
probably null |
|
|
IGL01539:Myo15b
|
APN |
11 |
115,754,299 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL01895:Myo15b
|
APN |
11 |
115,774,324 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02254:Myo15b
|
APN |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02343:Myo15b
|
APN |
11 |
115,764,226 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02349:Myo15b
|
APN |
11 |
115,753,931 (GRCm39) |
splice site |
probably benign |
|
|
IGL02368:Myo15b
|
APN |
11 |
115,767,828 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02576:Myo15b
|
APN |
11 |
115,780,879 (GRCm39) |
missense |
probably null |
0.97 |
|
IGL02650:Myo15b
|
APN |
11 |
115,777,337 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02661:Myo15b
|
APN |
11 |
115,774,895 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02716:Myo15b
|
APN |
11 |
115,774,535 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02733:Myo15b
|
APN |
11 |
115,775,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02951:Myo15b
|
APN |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03017:Myo15b
|
APN |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03029:Myo15b
|
APN |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
ANU74:Myo15b
|
UTSW |
11 |
115,769,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0092:Myo15b
|
UTSW |
11 |
115,753,812 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0255:Myo15b
|
UTSW |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Myo15b
|
UTSW |
11 |
115,773,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0652:Myo15b
|
UTSW |
11 |
115,755,468 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0711:Myo15b
|
UTSW |
11 |
115,774,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0815:Myo15b
|
UTSW |
11 |
115,757,162 (GRCm39) |
splice site |
probably benign |
|
|
R0961:Myo15b
|
UTSW |
11 |
115,773,280 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1066:Myo15b
|
UTSW |
11 |
115,770,577 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1221:Myo15b
|
UTSW |
11 |
115,777,546 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1240:Myo15b
|
UTSW |
11 |
115,771,327 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1275:Myo15b
|
UTSW |
11 |
115,774,318 (GRCm39) |
small deletion |
probably benign |
|
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1317:Myo15b
|
UTSW |
11 |
115,774,460 (GRCm39) |
missense |
probably null |
0.14 |
|
R1491:Myo15b
|
UTSW |
11 |
115,777,683 (GRCm39) |
splice site |
probably null |
|
|
R1552:Myo15b
|
UTSW |
11 |
115,757,461 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1731:Myo15b
|
UTSW |
11 |
115,782,386 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R1800:Myo15b
|
UTSW |
11 |
115,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1843:Myo15b
|
UTSW |
11 |
115,760,412 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1894:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Myo15b
|
UTSW |
11 |
115,773,080 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1934:Myo15b
|
UTSW |
11 |
115,754,310 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1939:Myo15b
|
UTSW |
11 |
115,778,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1945:Myo15b
|
UTSW |
11 |
115,769,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Myo15b
|
UTSW |
11 |
115,773,701 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2130:Myo15b
|
UTSW |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2138:Myo15b
|
UTSW |
11 |
115,774,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2176:Myo15b
|
UTSW |
11 |
115,757,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2415:Myo15b
|
UTSW |
11 |
115,770,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Myo15b
|
UTSW |
11 |
115,755,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3620:Myo15b
|
UTSW |
11 |
115,762,013 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3716:Myo15b
|
UTSW |
11 |
115,754,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4013:Myo15b
|
UTSW |
11 |
115,762,282 (GRCm39) |
nonsense |
probably null |
|
|
R4021:Myo15b
|
UTSW |
11 |
115,764,331 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4119:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4120:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4499:Myo15b
|
UTSW |
11 |
115,781,778 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4653:Myo15b
|
UTSW |
11 |
115,770,813 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4655:Myo15b
|
UTSW |
11 |
115,781,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Myo15b
|
UTSW |
11 |
115,752,761 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4702:Myo15b
|
UTSW |
11 |
115,774,834 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4777:Myo15b
|
UTSW |
11 |
115,770,478 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4833:Myo15b
|
UTSW |
11 |
115,778,428 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5083:Myo15b
|
UTSW |
11 |
115,757,482 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5121:Myo15b
|
UTSW |
11 |
115,776,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5146:Myo15b
|
UTSW |
11 |
115,782,024 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5535:Myo15b
|
UTSW |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5647:Myo15b
|
UTSW |
11 |
115,762,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5849:Myo15b
|
UTSW |
11 |
115,772,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5882:Myo15b
|
UTSW |
11 |
115,760,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5956:Myo15b
|
UTSW |
11 |
115,764,583 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6273:Myo15b
|
UTSW |
11 |
115,753,625 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6302:Myo15b
|
UTSW |
11 |
115,777,065 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6318:Myo15b
|
UTSW |
11 |
115,781,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6462:Myo15b
|
UTSW |
11 |
115,750,268 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6792:Myo15b
|
UTSW |
11 |
115,775,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo15b
|
UTSW |
11 |
115,781,540 (GRCm39) |
splice site |
probably null |
|
|
R7015:Myo15b
|
UTSW |
11 |
115,762,670 (GRCm39) |
missense |
|
|
|
R7020:Myo15b
|
UTSW |
11 |
115,757,493 (GRCm39) |
nonsense |
probably null |
|
|
R7096:Myo15b
|
UTSW |
11 |
115,782,324 (GRCm39) |
splice site |
probably null |
|
|
R7219:Myo15b
|
UTSW |
11 |
115,767,921 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7400:Myo15b
|
UTSW |
11 |
115,750,939 (GRCm39) |
missense |
|
|
|
R7413:Myo15b
|
UTSW |
11 |
115,768,970 (GRCm39) |
missense |
|
|
|
R7483:Myo15b
|
UTSW |
11 |
115,749,570 (GRCm39) |
missense |
|
|
|
R7523:Myo15b
|
UTSW |
11 |
115,781,684 (GRCm39) |
missense |
unknown |
|
|
R7737:Myo15b
|
UTSW |
11 |
115,778,749 (GRCm39) |
missense |
unknown |
|
|
R7784:Myo15b
|
UTSW |
11 |
115,752,166 (GRCm39) |
missense |
|
|
|
R7842:Myo15b
|
UTSW |
11 |
115,762,321 (GRCm39) |
missense |
|
|
|
R7921:Myo15b
|
UTSW |
11 |
115,778,004 (GRCm39) |
nonsense |
probably null |
|
|
R8065:Myo15b
|
UTSW |
11 |
115,778,769 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8183:Myo15b
|
UTSW |
11 |
115,773,843 (GRCm39) |
splice site |
probably null |
|
|
R8193:Myo15b
|
UTSW |
11 |
115,775,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Myo15b
|
UTSW |
11 |
115,767,827 (GRCm39) |
missense |
|
|
|
R8430:Myo15b
|
UTSW |
11 |
115,773,049 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8482:Myo15b
|
UTSW |
11 |
115,774,083 (GRCm39) |
nonsense |
probably null |
|
|
R8515:Myo15b
|
UTSW |
11 |
115,749,610 (GRCm39) |
missense |
|
|
|
R8798:Myo15b
|
UTSW |
11 |
115,754,232 (GRCm39) |
missense |
|
|
|
R8937:Myo15b
|
UTSW |
11 |
115,773,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8975:Myo15b
|
UTSW |
11 |
115,781,780 (GRCm39) |
missense |
unknown |
|
|
R9045:Myo15b
|
UTSW |
11 |
115,783,178 (GRCm39) |
makesense |
probably null |
|
|
R9117:Myo15b
|
UTSW |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9185:Myo15b
|
UTSW |
11 |
115,771,255 (GRCm39) |
missense |
unknown |
|
|
R9226:Myo15b
|
UTSW |
11 |
115,750,924 (GRCm39) |
missense |
|
|
|
R9302:Myo15b
|
UTSW |
11 |
115,776,238 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9318:Myo15b
|
UTSW |
11 |
115,775,965 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9336:Myo15b
|
UTSW |
11 |
115,771,064 (GRCm39) |
missense |
|
|
|
R9337:Myo15b
|
UTSW |
11 |
115,749,861 (GRCm39) |
missense |
|
|
|
R9338:Myo15b
|
UTSW |
11 |
115,762,238 (GRCm39) |
missense |
|
|
|
R9498:Myo15b
|
UTSW |
11 |
115,770,784 (GRCm39) |
missense |
|
|
|
R9500:Myo15b
|
UTSW |
11 |
115,777,466 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9602:Myo15b
|
UTSW |
11 |
115,769,269 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9642:Myo15b
|
UTSW |
11 |
115,772,335 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0020:Myo15b
|
UTSW |
11 |
115,762,625 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,778,751 (GRCm39) |
missense |
unknown |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,774,278 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- CACGAGGCCCATCAAAACTTTTCAG -3'
(R):5'- GATGATGACTTCCGCCATGAGTCC -3'
Sequencing Primer
(F):5'- GATAAATGGCGTCCACTTGC -3'
(R):5'- ATGAGTCCCAAGAGGCTGTC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation