Incidental Mutation 'R0201:Ugt1a10'
| ID |
258009 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ugt1a10
|
| Ensembl Gene |
ENSMUSG00000090165 |
| Gene Name |
UDP glycosyltransferase 1 family, polypeptide A10 |
| Synonyms |
A13 |
| MMRRC Submission |
038458-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.115)
|
| Stock # |
R0201 (G1)
|
| Quality Score |
55 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
88055388-88219004 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 88218249 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Leucine
at position 473
(P473L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108767
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014263]
[ENSMUST00000049289]
[ENSMUST00000058237]
[ENSMUST00000073049]
[ENSMUST00000073772]
[ENSMUST00000097659]
[ENSMUST00000113134]
[ENSMUST00000113135]
[ENSMUST00000113137]
[ENSMUST00000113138]
[ENSMUST00000113139]
[ENSMUST00000113142]
[ENSMUST00000126203]
[ENSMUST00000138182]
[ENSMUST00000140092]
[ENSMUST00000150634]
[ENSMUST00000173325]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000014263
AA Change: P474L
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000014263
Gene: ENSMUSG00000054545
AA Change: P474L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
1.2e-229 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
448 |
1e-8 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000049289
AA Change: P476L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000037258
Gene: ENSMUSG00000090171
AA Change: P476L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
28 |
524 |
2.2e-247 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
452 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000058237
AA Change: P474L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000058683
Gene: ENSMUSG00000090124
AA Change: P474L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
522 |
1.5e-234 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
361 |
450 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000073049
AA Change: P478L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000072803
Gene: ENSMUSG00000089960
AA Change: P478L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
30 |
526 |
5.8e-241 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
365 |
454 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000073772
AA Change: P471L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000073444
Gene: ENSMUSG00000090175
AA Change: P471L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
24 |
519 |
2.3e-232 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
358 |
447 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000097659
AA Change: P472L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000095263
Gene: ENSMUSG00000089943
AA Change: P472L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
25 |
520 |
6.7e-246 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
359 |
448 |
1.3e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113134
AA Change: P474L
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000108759
Gene: ENSMUSG00000054545
AA Change: P474L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
2.7e-232 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
361 |
450 |
4.5e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113135
AA Change: P474L
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000108760
Gene: ENSMUSG00000090124
AA Change: P474L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
1.2e-229 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
448 |
1e-8 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113137
AA Change: P474L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108762
Gene: ENSMUSG00000090145
AA Change: P474L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
1.3e-231 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
361 |
450 |
2.8e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113138
AA Change: P474L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108763
Gene: ENSMUSG00000090145
AA Change: P474L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
27 |
522 |
7.3e-229 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
363 |
448 |
6.6e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113139
AA Change: P473L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108764
Gene: ENSMUSG00000089675
AA Change: P473L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
521 |
3.6e-237 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
360 |
449 |
1.3e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113142
AA Change: P473L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108767
Gene: ENSMUSG00000090165
AA Change: P473L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
521 |
7.3e-231 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
360 |
449 |
1.3e-9 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124852
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173165
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000174821
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000126203
|
| SMART Domains |
Protein: ENSMUSP00000116653
Gene: ENSMUSG00000090124
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
62 |
4.6e-11 |
PFAM |
|
Pfam:UDPGT
|
59 |
127 |
8.9e-24 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138182
|
| SMART Domains |
Protein: ENSMUSP00000119985
Gene: ENSMUSG00000090165
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
62 |
7e-11 |
PFAM |
|
Pfam:UDPGT
|
58 |
207 |
1.9e-90 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
137 |
207 |
4.8e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140092
|
| SMART Domains |
Protein: ENSMUSP00000115642
Gene: ENSMUSG00000054545
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UDPGT
|
1 |
166 |
9.3e-98 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
96 |
166 |
4.9e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150634
|
| SMART Domains |
Protein: ENSMUSP00000123452
Gene: ENSMUSG00000090124
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
62 |
9.5e-11 |
PFAM |
|
Pfam:UDPGT
|
58 |
207 |
2e-90 |
PFAM |
|
Pfam:Glyco_tran_28_C
|
137 |
207 |
4.8e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173325
|
| SMART Domains |
Protein: ENSMUSP00000134443
Gene: ENSMUSG00000090165
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
Pfam:UDPGT
|
26 |
61 |
3.4e-10 |
PFAM |
|
Pfam:UDPGT
|
59 |
210 |
8.9e-92 |
PFAM |
|
| Meta Mutation Damage Score |
0.5212 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 94.2%
|
| Validation Efficiency |
97% (91/94) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamdec1 |
A |
G |
14: 68,581,957 (GRCm38) |
|
probably null |
Het |
| Adamts16 |
T |
A |
13: 70,779,644 (GRCm38) |
Q492L |
possibly damaging |
Het |
| Aplnr |
A |
G |
2: 85,137,177 (GRCm38) |
D182G |
probably damaging |
Het |
| Arnt2 |
G |
T |
7: 84,361,659 (GRCm38) |
S3* |
probably null |
Het |
| Asxl3 |
T |
C |
18: 22,523,154 (GRCm38) |
V1407A |
probably benign |
Het |
| Atg13 |
A |
T |
2: 91,684,762 (GRCm38) |
|
probably null |
Het |
| Atm |
A |
T |
9: 53,454,279 (GRCm38) |
|
probably benign |
Het |
| Birc6 |
T |
G |
17: 74,609,327 (GRCm38) |
V1746G |
possibly damaging |
Het |
| Cbln1 |
G |
T |
8: 87,472,113 (GRCm38) |
T43K |
probably benign |
Het |
| Cbx5 |
T |
C |
15: 103,199,700 (GRCm38) |
T173A |
probably damaging |
Het |
| Cc2d2a |
A |
G |
5: 43,737,512 (GRCm38) |
Y1437C |
probably damaging |
Het |
| Ccdc78 |
C |
A |
17: 25,789,236 (GRCm38) |
|
probably benign |
Het |
| Cd2bp2 |
A |
G |
7: 127,193,828 (GRCm38) |
Y341H |
probably damaging |
Het |
| Cdhr5 |
T |
A |
7: 141,276,378 (GRCm38) |
D88V |
probably damaging |
Het |
| Ces1f |
T |
A |
8: 93,267,329 (GRCm38) |
T275S |
probably null |
Het |
| Clca4a |
T |
C |
3: 144,960,717 (GRCm38) |
N458S |
probably benign |
Het |
| Cog5 |
A |
G |
12: 31,839,841 (GRCm38) |
K521R |
probably damaging |
Het |
| Csf2ra |
T |
A |
19: 61,225,568 (GRCm38) |
T305S |
probably benign |
Het |
| Csmd3 |
T |
A |
15: 47,619,729 (GRCm38) |
|
probably benign |
Het |
| Cts6 |
T |
A |
13: 61,201,499 (GRCm38) |
R132* |
probably null |
Het |
| D5Ertd579e |
G |
T |
5: 36,616,465 (GRCm38) |
N195K |
probably damaging |
Het |
| Ddx1 |
A |
G |
12: 13,223,808 (GRCm38) |
V606A |
probably damaging |
Het |
| Dip2b |
G |
A |
15: 100,186,147 (GRCm38) |
D884N |
probably damaging |
Het |
| Ehhadh |
A |
G |
16: 21,773,493 (GRCm38) |
|
probably null |
Het |
| Enpp1 |
T |
A |
10: 24,653,917 (GRCm38) |
T608S |
probably benign |
Het |
| Fancm |
T |
C |
12: 65,101,632 (GRCm38) |
Y674H |
probably damaging |
Het |
| Fat4 |
T |
A |
3: 38,891,596 (GRCm38) |
V1546D |
probably damaging |
Het |
| Fsd1 |
G |
A |
17: 55,990,522 (GRCm38) |
A158T |
probably benign |
Het |
| Fzd2 |
T |
A |
11: 102,606,122 (GRCm38) |
M464K |
probably damaging |
Het |
| Gjc2 |
A |
G |
11: 59,177,590 (GRCm38) |
F22S |
possibly damaging |
Het |
| Gm13101 |
T |
C |
4: 143,964,890 (GRCm38) |
E421G |
probably damaging |
Het |
| Gria2 |
T |
C |
3: 80,707,838 (GRCm38) |
Y445C |
probably damaging |
Het |
| Hsdl1 |
T |
A |
8: 119,566,256 (GRCm38) |
I147F |
possibly damaging |
Het |
| Ifi44 |
T |
C |
3: 151,745,636 (GRCm38) |
Y226C |
probably damaging |
Het |
| Il16 |
A |
G |
7: 83,722,308 (GRCm38) |
C97R |
probably damaging |
Het |
| Impg1 |
A |
T |
9: 80,345,561 (GRCm38) |
S369T |
probably damaging |
Het |
| Jmjd1c |
A |
G |
10: 67,219,109 (GRCm38) |
T390A |
unknown |
Het |
| Lgi1 |
A |
G |
19: 38,301,293 (GRCm38) |
E269G |
possibly damaging |
Het |
| Lrp6 |
G |
T |
6: 134,450,897 (GRCm38) |
Y1577* |
probably null |
Het |
| Lrrc74a |
G |
T |
12: 86,761,773 (GRCm38) |
|
probably benign |
Het |
| Man1c1 |
A |
T |
4: 134,640,398 (GRCm38) |
|
probably null |
Het |
| Map1lc3b |
A |
C |
8: 121,590,550 (GRCm38) |
Q9P |
possibly damaging |
Het |
| Mboat1 |
G |
A |
13: 30,202,375 (GRCm38) |
R124H |
probably benign |
Het |
| Mcu |
A |
G |
10: 59,456,677 (GRCm38) |
L60P |
probably damaging |
Het |
| Mrs2 |
G |
T |
13: 25,018,534 (GRCm38) |
Q75K |
probably benign |
Het |
| Muc2 |
CGTG |
CGTGTG |
7: 141,699,185 (GRCm38) |
|
probably null |
Het |
| Neb |
G |
A |
2: 52,206,878 (GRCm38) |
|
probably benign |
Het |
| Nlrp2 |
C |
T |
7: 5,328,329 (GRCm38) |
G356D |
probably benign |
Het |
| Notch3 |
A |
G |
17: 32,156,148 (GRCm38) |
|
probably benign |
Het |
| Npr2 |
A |
C |
4: 43,641,617 (GRCm38) |
S474R |
probably damaging |
Het |
| Nupl1 |
A |
G |
14: 60,244,616 (GRCm38) |
F100L |
probably benign |
Het |
| Osbpl6 |
A |
C |
2: 76,546,042 (GRCm38) |
D87A |
possibly damaging |
Het |
| Pabpc2 |
A |
T |
18: 39,775,307 (GRCm38) |
M542L |
probably benign |
Het |
| Papln |
A |
G |
12: 83,783,027 (GRCm38) |
|
probably benign |
Het |
| Parpbp |
T |
C |
10: 88,092,896 (GRCm38) |
I561V |
possibly damaging |
Het |
| Pcdhb13 |
C |
T |
18: 37,442,581 (GRCm38) |
A4V |
probably benign |
Het |
| Pelp1 |
T |
C |
11: 70,395,704 (GRCm38) |
T533A |
possibly damaging |
Het |
| Poldip3 |
T |
A |
15: 83,135,296 (GRCm38) |
M182L |
probably benign |
Het |
| Por |
T |
C |
5: 135,731,178 (GRCm38) |
S240P |
possibly damaging |
Het |
| Pramef20 |
A |
T |
4: 144,377,273 (GRCm38) |
|
probably benign |
Het |
| Prss22 |
A |
T |
17: 23,996,301 (GRCm38) |
V167D |
probably damaging |
Het |
| Prss37 |
A |
C |
6: 40,516,349 (GRCm38) |
L61R |
probably damaging |
Het |
| Psmd1 |
C |
T |
1: 86,118,616 (GRCm38) |
T702M |
probably benign |
Het |
| Pxdn |
G |
T |
12: 30,002,431 (GRCm38) |
G869V |
possibly damaging |
Het |
| Rabgap1l |
A |
G |
1: 160,453,745 (GRCm38) |
|
probably benign |
Het |
| Rapgef6 |
T |
C |
11: 54,619,941 (GRCm38) |
V228A |
probably damaging |
Het |
| Rnf169 |
T |
C |
7: 99,926,003 (GRCm38) |
R462G |
possibly damaging |
Het |
| Rnft2 |
A |
G |
5: 118,194,680 (GRCm38) |
|
probably benign |
Het |
| Sgo2b |
T |
C |
8: 63,926,636 (GRCm38) |
D1054G |
probably benign |
Het |
| Sh3bgr |
T |
C |
16: 96,228,517 (GRCm38) |
|
probably benign |
Het |
| Slc12a4 |
A |
G |
8: 105,945,350 (GRCm38) |
V910A |
possibly damaging |
Het |
| Slc6a12 |
A |
T |
6: 121,355,372 (GRCm38) |
I222F |
probably benign |
Het |
| Spty2d1 |
G |
A |
7: 46,997,901 (GRCm38) |
R427* |
probably null |
Het |
| Ssc5d |
A |
G |
7: 4,944,663 (GRCm38) |
T1339A |
probably benign |
Het |
| Sspo |
A |
C |
6: 48,455,752 (GRCm38) |
E854A |
possibly damaging |
Het |
| Stx7 |
A |
G |
10: 24,185,079 (GRCm38) |
|
probably benign |
Het |
| Styk1 |
A |
T |
6: 131,301,730 (GRCm38) |
|
probably benign |
Het |
| Tex33 |
T |
A |
15: 78,378,828 (GRCm38) |
M209L |
probably damaging |
Het |
| Tmem163 |
T |
G |
1: 127,668,637 (GRCm38) |
|
probably benign |
Het |
| Tmppe |
C |
CT |
9: 114,404,639 (GRCm38) |
|
probably null |
Het |
| Tmx2 |
A |
G |
2: 84,673,082 (GRCm38) |
V229A |
probably benign |
Het |
| Top2b |
T |
C |
14: 16,383,174 (GRCm38) |
L54P |
probably damaging |
Het |
| Trim62 |
A |
T |
4: 128,902,550 (GRCm38) |
Y280F |
probably benign |
Het |
| Tssk4 |
A |
T |
14: 55,651,559 (GRCm38) |
K181* |
probably null |
Het |
| Tssk4 |
A |
T |
14: 55,651,560 (GRCm38) |
K181M |
probably damaging |
Het |
| Ubn1 |
A |
G |
16: 5,064,614 (GRCm38) |
D313G |
probably damaging |
Het |
|
| Other mutations in Ugt1a10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01126:Ugt1a10
|
APN |
1 |
88,055,987 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
IGL02219:Ugt1a10
|
APN |
1 |
88,056,058 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02511:Ugt1a10
|
APN |
1 |
88,055,863 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02990:Ugt1a10
|
APN |
1 |
88,055,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4142001:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
R0201:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0522:Ugt1a10
|
UTSW |
1 |
88,218,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0525:Ugt1a10
|
UTSW |
1 |
88,218,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0554:Ugt1a10
|
UTSW |
1 |
88,056,095 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0748:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0811:Ugt1a10
|
UTSW |
1 |
88,056,182 (GRCm38) |
missense |
probably benign |
0.33 |
|
R0812:Ugt1a10
|
UTSW |
1 |
88,056,182 (GRCm38) |
missense |
probably benign |
0.33 |
|
R1129:Ugt1a10
|
UTSW |
1 |
88,055,609 (GRCm38) |
missense |
probably benign |
|
|
R1207:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1432:Ugt1a10
|
UTSW |
1 |
88,216,260 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1457:Ugt1a10
|
UTSW |
1 |
88,055,711 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1469:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1972:Ugt1a10
|
UTSW |
1 |
88,056,047 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1973:Ugt1a10
|
UTSW |
1 |
88,056,047 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2039:Ugt1a10
|
UTSW |
1 |
88,055,981 (GRCm38) |
missense |
probably benign |
0.32 |
|
R2307:Ugt1a10
|
UTSW |
1 |
88,055,947 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3952:Ugt1a10
|
UTSW |
1 |
88,216,140 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3973:Ugt1a10
|
UTSW |
1 |
88,216,140 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4232:Ugt1a10
|
UTSW |
1 |
88,056,210 (GRCm38) |
missense |
probably benign |
0.39 |
|
R4392:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4393:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4402:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4417:Ugt1a10
|
UTSW |
1 |
88,055,995 (GRCm38) |
missense |
probably benign |
|
|
R4474:Ugt1a10
|
UTSW |
1 |
88,215,928 (GRCm38) |
intron |
probably benign |
|
|
R4476:Ugt1a10
|
UTSW |
1 |
88,215,928 (GRCm38) |
intron |
probably benign |
|
|
R4515:Ugt1a10
|
UTSW |
1 |
88,056,197 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4579:Ugt1a10
|
UTSW |
1 |
88,056,116 (GRCm38) |
missense |
probably benign |
|
|
R4582:Ugt1a10
|
UTSW |
1 |
88,055,741 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4609:Ugt1a10
|
UTSW |
1 |
88,055,482 (GRCm38) |
start codon destroyed |
possibly damaging |
0.92 |
|
R4627:Ugt1a10
|
UTSW |
1 |
88,218,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4790:Ugt1a10
|
UTSW |
1 |
88,056,287 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4799:Ugt1a10
|
UTSW |
1 |
88,215,928 (GRCm38) |
intron |
probably benign |
|
|
R4910:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4915:Ugt1a10
|
UTSW |
1 |
88,055,924 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5110:Ugt1a10
|
UTSW |
1 |
88,056,252 (GRCm38) |
splice site |
probably null |
|
|
R5168:Ugt1a10
|
UTSW |
1 |
88,055,809 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5329:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ugt1a10
|
UTSW |
1 |
88,055,910 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5374:Ugt1a10
|
UTSW |
1 |
88,055,910 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5615:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
R6498:Ugt1a10
|
UTSW |
1 |
88,216,140 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6727:Ugt1a10
|
UTSW |
1 |
88,056,257 (GRCm38) |
splice site |
probably null |
|
|
R6809:Ugt1a10
|
UTSW |
1 |
88,055,925 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6924:Ugt1a10
|
UTSW |
1 |
88,055,657 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6967:Ugt1a10
|
UTSW |
1 |
88,215,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7913:Ugt1a10
|
UTSW |
1 |
88,055,755 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9165:Ugt1a10
|
UTSW |
1 |
88,055,787 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9264:Ugt1a10
|
UTSW |
1 |
88,055,671 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R9475:Ugt1a10
|
UTSW |
1 |
88,216,260 (GRCm38) |
missense |
probably damaging |
1.00 |
|
S24628:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
X0013:Ugt1a10
|
UTSW |
1 |
88,216,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Ugt1a10
|
UTSW |
1 |
88,055,842 (GRCm38) |
missense |
probably benign |
0.20 |
|
Z1190:Ugt1a10
|
UTSW |
1 |
88,216,158 (GRCm38) |
small deletion |
probably benign |
|
|
| Predicted Primers |
|
| Posted On |
2015-01-14 |
Incidental Mutation