Mutagenetix > Incidental Mutation

Incidental Mutation 'R3705:Tenm2'

258716

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

D3Bwg1534e, Odz2, 9330187F13Rik, Ten-m2, 2610040L17Rik

MMRRC Submission

040698-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.569) question?

Stock #

R3705 (G1)

Quality Score

209

Status

Validated

Chromosome

Chromosomal Location

35897483-37126791 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 35959153 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Valine at position 1132 (D1132V)

Ref Sequence

ENSEMBL: ENSMUSP00000052014 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057207
AA Change: D1132V

PolyPhen 2 Score 0.974 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: D1132V

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000102801
AA Change: D1131V

PolyPhen 2 Score 0.889 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: D1131V

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000163524
AA Change: D1131V

PolyPhen 2 Score 0.889 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: D1131V

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Meta Mutation Damage Score

0.0979

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.0%

Validation Efficiency

100% (46/46)

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9930111J21Rik1	T	C	11: 48,838,803 (GRCm39)	T595A	possibly damaging	Het
Abca12	T	C	1: 71,324,864 (GRCm39)	D1538G	probably damaging	Het
Asap3	TGAGGAGGAGGAGGAGGA	TGAGGAGGAGGAGGAGGAGGA	4: 135,968,552 (GRCm39)		probably benign	Het
Bcap29	T	C	12: 31,667,151 (GRCm39)	H170R	probably benign	Het
Bltp1	T	A	3: 37,041,730 (GRCm39)	C2703S	probably damaging	Het
Brwd3	A	G	X: 107,804,021 (GRCm39)		probably benign	Het
Capn1	T	C	19: 6,057,401 (GRCm39)	E349G	probably damaging	Het
Cers3	G	T	7: 66,435,823 (GRCm39)	A261S	probably benign	Het
Csf3r	A	G	4: 125,926,078 (GRCm39)	D221G	possibly damaging	Het
Cubn	T	A	2: 13,355,754 (GRCm39)	H1826L	probably damaging	Het
Dnajc19	A	G	3: 34,134,378 (GRCm39)		probably null	Het
Dync1h1	G	A	12: 110,607,020 (GRCm39)	V2566I	possibly damaging	Het
Ehd1	A	G	19: 6,348,330 (GRCm39)	D436G		Het
Fam133b	T	C	5: 3,611,034 (GRCm39)		probably benign	Het
Fam43b	G	C	4: 138,122,409 (GRCm39)	R304G	probably benign	Het
Gpnmb	T	A	6: 49,028,799 (GRCm39)	I439N	possibly damaging	Het
Grm1	G	A	10: 10,658,473 (GRCm39)	T339I	possibly damaging	Het
Gtpbp3	T	G	8: 71,944,779 (GRCm39)	S345A	probably benign	Het
Hdac4	A	G	1: 91,862,416 (GRCm39)		probably benign	Het
Hfm1	A	G	5: 107,040,705 (GRCm39)		probably benign	Het
Ift172	A	G	5: 31,418,781 (GRCm39)		probably null	Het
Igfn1	T	C	1: 135,896,147 (GRCm39)	N1473S	probably benign	Het
Jak3	A	G	8: 72,134,166 (GRCm39)	K423E	probably damaging	Het
Kifc3	G	A	8: 95,830,656 (GRCm39)		probably benign	Het
Lrrc8d	T	C	5: 105,961,341 (GRCm39)	S584P	probably damaging	Het
Nipal4	T	C	11: 46,052,678 (GRCm39)		probably benign	Het
Nisch	A	G	14: 30,898,702 (GRCm39)		probably benign	Het
Nmur2	T	C	11: 55,931,300 (GRCm39)	Y137C	probably damaging	Het
Nod2	T	C	8: 89,379,948 (GRCm39)	S150P	probably benign	Het
Or5w22	A	G	2: 87,362,412 (GRCm39)	I12V	probably benign	Het
Pdgfc	T	C	3: 81,111,751 (GRCm39)		probably null	Het
Phldb1	G	T	9: 44,605,691 (GRCm39)	H1323N	probably damaging	Het
Ppp1r14c	A	G	10: 3,373,524 (GRCm39)	I112V	possibly damaging	Het
Pramel26	T	C	4: 143,538,345 (GRCm39)	T209A	probably benign	Het
Rcc1l	A	T	5: 134,183,030 (GRCm39)	V414E	probably damaging	Het
Riok3	A	G	18: 12,282,011 (GRCm39)	M327V	probably benign	Het
Sf3b4	T	C	3: 96,083,944 (GRCm39)		probably benign	Het
Spag6	A	G	2: 18,715,368 (GRCm39)	Y49C	probably damaging	Het
Syngap1	T	C	17: 27,178,994 (GRCm39)	S495P	probably damaging	Het
Tedc2	A	G	17: 24,435,361 (GRCm39)	S343P	probably benign	Het
Tmem63a	G	A	1: 180,790,679 (GRCm39)	D446N	possibly damaging	Het
Top1	G	A	2: 160,544,744 (GRCm39)		probably null	Het
Tox3	G	T	8: 90,975,533 (GRCm39)	T366K	possibly damaging	Het
Tph2	G	A	10: 114,955,798 (GRCm39)	Q332*	probably null	Het
Zfr2	T	G	10: 81,081,913 (GRCm39)	V493G	probably benign	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,097,726 (GRCm39)	splice site	probably benign
IGL00834:Tenm2	APN	11	35,915,085 (GRCm39)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	35,899,560 (GRCm39)	nonsense	probably null
IGL00937:Tenm2	APN	11	35,915,450 (GRCm39)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	35,932,371 (GRCm39)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	35,915,075 (GRCm39)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	35,918,232 (GRCm39)	nonsense	probably null
IGL01539:Tenm2	APN	11	35,997,654 (GRCm39)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,755,711 (GRCm39)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	35,937,768 (GRCm39)	missense	probably benign
IGL01821:Tenm2	APN	11	35,914,710 (GRCm39)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	35,918,078 (GRCm39)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,097,922 (GRCm39)	missense	probably benign
IGL02449:Tenm2	APN	11	35,914,449 (GRCm39)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	35,942,743 (GRCm39)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,097,912 (GRCm39)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	35,959,285 (GRCm39)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	35,937,857 (GRCm39)	nonsense	probably null
IGL02928:Tenm2	APN	11	35,917,997 (GRCm39)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	35,932,471 (GRCm39)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	35,915,375 (GRCm39)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	35,914,157 (GRCm39)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	35,963,603 (GRCm39)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	35,942,852 (GRCm39)	splice site	probably null
IGL03381:Tenm2	APN	11	35,959,238 (GRCm39)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	35,915,370 (GRCm39)	missense	probably damaging	1.00
browser	UTSW	11	35,937,592 (GRCm39)	critical splice donor site	probably null
mosaic	UTSW	11	35,954,602 (GRCm39)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,164,235 (GRCm39)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,054,557 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	35,954,729 (GRCm39)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	35,914,184 (GRCm39)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,097,951 (GRCm39)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,054,557 (GRCm39)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	35,915,607 (GRCm39)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,834,803 (GRCm39)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	35,915,636 (GRCm39)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,755,511 (GRCm39)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	35,899,185 (GRCm39)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	35,932,486 (GRCm39)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	35,959,421 (GRCm39)	splice site	probably benign
R1374:Tenm2	UTSW	11	35,899,281 (GRCm39)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,191,047 (GRCm39)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	35,937,896 (GRCm39)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	35,997,610 (GRCm39)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1722:Tenm2	UTSW	11	35,898,930 (GRCm39)	missense	probably damaging	1.00
R1756:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	35,914,209 (GRCm39)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	35,954,004 (GRCm39)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	35,938,374 (GRCm39)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	35,938,091 (GRCm39)	nonsense	probably null
R2117:Tenm2	UTSW	11	35,915,681 (GRCm39)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,755,689 (GRCm39)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	35,937,604 (GRCm39)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	35,918,018 (GRCm39)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	35,914,800 (GRCm39)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	35,914,193 (GRCm39)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	35,942,644 (GRCm39)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	35,942,644 (GRCm39)	missense	probably benign	0.00
R3820:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	35,915,147 (GRCm39)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	35,938,365 (GRCm39)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,030,401 (GRCm39)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	35,937,901 (GRCm39)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	35,899,482 (GRCm39)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	35,918,225 (GRCm39)	missense	probably benign
R4395:Tenm2	UTSW	11	35,915,451 (GRCm39)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	35,899,172 (GRCm39)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	35,953,931 (GRCm39)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	35,937,607 (GRCm39)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	35,937,963 (GRCm39)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	35,915,275 (GRCm39)	missense	probably damaging	0.99
R4669:Tenm2	UTSW	11	35,901,314 (GRCm39)	missense	probably damaging	1.00
R4687:Tenm2	UTSW	11	35,939,924 (GRCm39)	missense	probably benign
R4711:Tenm2	UTSW	11	36,191,039 (GRCm39)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	35,918,117 (GRCm39)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	35,914,847 (GRCm39)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	35,914,315 (GRCm39)	nonsense	probably null
R4870:Tenm2	UTSW	11	35,969,396 (GRCm39)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,097,907 (GRCm39)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	35,959,208 (GRCm39)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	35,915,460 (GRCm39)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,834,989 (GRCm39)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	35,915,633 (GRCm39)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	35,938,028 (GRCm39)	nonsense	probably null
R5343:Tenm2	UTSW	11	35,960,330 (GRCm39)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,755,503 (GRCm39)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,054,541 (GRCm39)	splice site	probably null
R5677:Tenm2	UTSW	11	36,032,510 (GRCm39)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	35,914,626 (GRCm39)	missense	probably benign	0.34
R5707:Tenm2	UTSW	11	35,938,009 (GRCm39)	missense	possibly damaging	0.79
R6026:Tenm2	UTSW	11	35,963,556 (GRCm39)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,054,544 (GRCm39)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	35,899,473 (GRCm39)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	35,899,610 (GRCm39)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,030,517 (GRCm39)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	35,937,621 (GRCm39)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,755,686 (GRCm39)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	35,901,334 (GRCm39)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	35,954,602 (GRCm39)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	35,937,592 (GRCm39)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	35,937,711 (GRCm39)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	35,914,407 (GRCm39)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,062,236 (GRCm39)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,054,644 (GRCm39)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	35,915,009 (GRCm39)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	35,932,378 (GRCm39)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,062,263 (GRCm39)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	35,939,956 (GRCm39)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	35,963,625 (GRCm39)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	35,914,298 (GRCm39)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	35,960,241 (GRCm39)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,755,768 (GRCm39)	missense	probably benign
R7504:Tenm2	UTSW	11	36,030,570 (GRCm39)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	35,942,727 (GRCm39)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	35,969,408 (GRCm39)	splice site	probably null
R7527:Tenm2	UTSW	11	36,097,803 (GRCm39)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	35,997,563 (GRCm39)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	35,938,174 (GRCm39)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,755,762 (GRCm39)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	35,960,388 (GRCm39)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	35,914,133 (GRCm39)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	35,901,276 (GRCm39)	missense	probably damaging	0.99
R7803:Tenm2	UTSW	11	35,937,943 (GRCm39)	missense	probably damaging	0.98
R7834:Tenm2	UTSW	11	35,915,681 (GRCm39)	missense	probably damaging	1.00
R7838:Tenm2	UTSW	11	35,997,626 (GRCm39)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,030,471 (GRCm39)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	35,918,048 (GRCm39)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	35,899,137 (GRCm39)	missense	probably benign
R8306:Tenm2	UTSW	11	35,960,196 (GRCm39)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	35,914,428 (GRCm39)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	35,914,428 (GRCm39)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	35,918,022 (GRCm39)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	35,942,788 (GRCm39)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,834,861 (GRCm39)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	35,942,688 (GRCm39)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	35,930,722 (GRCm39)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	35,959,303 (GRCm39)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	35,915,327 (GRCm39)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	35,914,474 (GRCm39)	missense	probably damaging	0.99
R9373:Tenm2	UTSW	11	35,930,713 (GRCm39)	missense	probably damaging	1.00
R9408:Tenm2	UTSW	11	35,960,246 (GRCm39)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,032,396 (GRCm39)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,112,286 (GRCm39)	missense	probably benign
R9489:Tenm2	UTSW	11	36,834,791 (GRCm39)	missense	probably damaging	0.99
R9711:Tenm2	UTSW	11	35,915,341 (GRCm39)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	35,915,030 (GRCm39)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	35,915,027 (GRCm39)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	35,915,557 (GRCm39)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,164,094 (GRCm39)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,191,162 (GRCm39)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	35,899,061 (GRCm39)	missense	possibly damaging	0.95
Z1177:Tenm2	UTSW	11	36,275,957 (GRCm39)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- GCACTTAGCATGGCTTCCTG -3'
(R):5'- CGTTATCTCAGCTCTAGAACTGC -3'

Sequencing Primer
(F):5'- AGCATGGCTTCCTGTTTTCTGAC -3'
(R):5'- TCAGCTCTAGAACTGCAGGGTAC -3'

Posted On

2015-01-23