Incidental Mutation 'R3716:Mink1'
| ID |
259925 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mink1
|
| Ensembl Gene |
ENSMUSG00000020827 |
| Gene Name |
misshapen-like kinase 1 (zebrafish) |
| Synonyms |
Map4k6, Ysk2, MINK, Misshapen/NIKs-related kinase |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R3716 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
70562881-70614483 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 70607761 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 584
(L584Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072091
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072237]
[ENSMUST00000072873]
[ENSMUST00000079244]
[ENSMUST00000102558]
[ENSMUST00000102559]
|
| AlphaFold |
Q9JM52 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072237
AA Change: L584Q
PolyPhen 2
Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000072091
Gene: ENSMUSG00000020827
AA Change: L584Q
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
25 |
289 |
1.86e-91 |
SMART |
|
low complexity region
|
307 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
351 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
557 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
620 |
633 |
N/A |
INTRINSIC |
|
low complexity region
|
646 |
659 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
738 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
874 |
N/A |
INTRINSIC |
|
CNH
|
1026 |
1324 |
1.58e-113 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000072873
AA Change: L584Q
PolyPhen 2
Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000072649
Gene: ENSMUSG00000020827
AA Change: L584Q
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
25 |
289 |
1.86e-91 |
SMART |
|
low complexity region
|
307 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
351 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
557 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
620 |
633 |
N/A |
INTRINSIC |
|
low complexity region
|
646 |
659 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
738 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
853 |
N/A |
INTRINSIC |
|
CNH
|
1019 |
1317 |
1.58e-113 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000079244
AA Change: L581Q
PolyPhen 2
Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000078234
Gene: ENSMUSG00000020827
AA Change: L581Q
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
25 |
289 |
1.86e-91 |
SMART |
|
low complexity region
|
314 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
348 |
493 |
N/A |
INTRINSIC |
|
low complexity region
|
554 |
566 |
N/A |
INTRINSIC |
|
low complexity region
|
617 |
630 |
N/A |
INTRINSIC |
|
low complexity region
|
643 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
716 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
826 |
850 |
N/A |
INTRINSIC |
|
CNH
|
1016 |
1314 |
1.58e-113 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000102558
AA Change: L584Q
PolyPhen 2
Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000099618
Gene: ENSMUSG00000020827
AA Change: L584Q
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
25 |
289 |
1.86e-91 |
SMART |
|
low complexity region
|
307 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
351 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
557 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
620 |
633 |
N/A |
INTRINSIC |
|
low complexity region
|
646 |
659 |
N/A |
INTRINSIC |
|
low complexity region
|
792 |
816 |
N/A |
INTRINSIC |
|
CNH
|
982 |
1280 |
1.58e-113 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000102559
AA Change: L584Q
PolyPhen 2
Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000099619
Gene: ENSMUSG00000020827
AA Change: L584Q
| Domain | Start | End | E-Value | Type |
|---|
|
S_TKc
|
25 |
289 |
1.86e-91 |
SMART |
|
low complexity region
|
307 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
351 |
496 |
N/A |
INTRINSIC |
|
low complexity region
|
557 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
620 |
633 |
N/A |
INTRINSIC |
|
low complexity region
|
646 |
659 |
N/A |
INTRINSIC |
|
low complexity region
|
800 |
824 |
N/A |
INTRINSIC |
|
CNH
|
990 |
1288 |
1.58e-113 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125853
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132208
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133310
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000136663
AA Change: L437Q
|
| SMART Domains |
Protein: ENSMUSP00000117959
Gene: ENSMUSG00000020827
AA Change: L437Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase_Tyr
|
1 |
140 |
2.3e-22 |
PFAM |
|
Pfam:Pkinase
|
1 |
143 |
1.6e-30 |
PFAM |
|
low complexity region
|
161 |
192 |
N/A |
INTRINSIC |
|
coiled coil region
|
204 |
349 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
423 |
N/A |
INTRINSIC |
|
low complexity region
|
474 |
487 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
573 |
592 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
728 |
N/A |
INTRINSIC |
|
CNH
|
880 |
1178 |
1.58e-113 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142650
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149845
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000152857
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153503
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000178764
|
| Meta Mutation Damage Score |
0.0603 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 50 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9930111J21Rik2 |
A |
T |
11: 49,019,536 (GRCm38) |
L690H |
probably damaging |
Het |
| Abtb3 |
C |
T |
10: 85,561,528 (GRCm38) |
H442Y |
probably damaging |
Het |
| Acaa1b |
A |
G |
9: 119,156,641 (GRCm38) |
V72A |
probably benign |
Het |
| Actl7a |
T |
C |
4: 56,744,295 (GRCm38) |
L274P |
possibly damaging |
Het |
| Ankrd50 |
T |
C |
3: 38,454,150 (GRCm38) |
E433G |
probably damaging |
Het |
| Ano6 |
A |
G |
15: 95,913,379 (GRCm38) |
D120G |
probably damaging |
Het |
| Bbs10 |
A |
G |
10: 111,301,134 (GRCm38) |
K703E |
probably benign |
Het |
| Canx |
A |
G |
11: 50,304,474 (GRCm38) |
S256P |
probably benign |
Het |
| Caps2 |
A |
G |
10: 112,200,732 (GRCm38) |
H399R |
probably benign |
Het |
| Col6a6 |
A |
C |
9: 105,782,174 (GRCm38) |
L524R |
probably damaging |
Het |
| Dab1 |
C |
T |
4: 104,731,751 (GRCm38) |
A524V |
probably benign |
Het |
| Dglucy |
A |
T |
12: 100,850,116 (GRCm38) |
N339I |
probably damaging |
Het |
| Dhrs4 |
G |
T |
14: 55,478,905 (GRCm38) |
M1I |
probably null |
Het |
| Disp1 |
A |
T |
1: 183,087,751 (GRCm38) |
L1035Q |
probably damaging |
Het |
| Ephb1 |
T |
C |
9: 102,194,800 (GRCm38) |
E260G |
probably damaging |
Het |
| Fetub |
T |
A |
16: 22,935,693 (GRCm38) |
C217S |
probably damaging |
Het |
| Firrm |
T |
C |
1: 163,956,888 (GRCm38) |
I779M |
probably damaging |
Het |
| Frem2 |
T |
C |
3: 53,572,360 (GRCm38) |
S1971G |
probably damaging |
Het |
| Gria2 |
A |
G |
3: 80,741,004 (GRCm38) |
Y142H |
possibly damaging |
Het |
| Hivep1 |
C |
T |
13: 42,158,495 (GRCm38) |
H1404Y |
probably damaging |
Het |
| Il21r |
A |
G |
7: 125,632,269 (GRCm38) |
K290E |
probably damaging |
Het |
| Inpp5f |
C |
G |
7: 128,690,670 (GRCm38) |
L17V |
probably damaging |
Het |
| Kcnh3 |
A |
G |
15: 99,232,765 (GRCm38) |
N421S |
possibly damaging |
Het |
| Krt33a |
A |
C |
11: 100,014,165 (GRCm38) |
C172G |
probably benign |
Het |
| Lrp6 |
A |
T |
6: 134,507,447 (GRCm38) |
H404Q |
probably damaging |
Het |
| Macf1 |
T |
C |
4: 123,473,502 (GRCm38) |
T924A |
probably benign |
Het |
| Mepe |
C |
A |
5: 104,337,428 (GRCm38) |
H145N |
probably benign |
Het |
| Mesp2 |
T |
G |
7: 79,812,794 (GRCm38) |
L366R |
possibly damaging |
Het |
| Mms19 |
A |
G |
19: 41,944,735 (GRCm38) |
V997A |
probably damaging |
Het |
| Mroh7 |
T |
C |
4: 106,704,210 (GRCm38) |
E612G |
probably benign |
Het |
| Myo15b |
G |
T |
11: 115,863,413 (GRCm38) |
C913F |
probably benign |
Het |
| Nav1 |
A |
T |
1: 135,450,630 (GRCm38) |
I1653K |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,277,470 (GRCm38) |
E1948G |
probably damaging |
Het |
| Nelfcd |
T |
C |
2: 174,423,005 (GRCm38) |
V179A |
possibly damaging |
Het |
| Obscn |
C |
T |
11: 59,082,661 (GRCm38) |
C2157Y |
probably damaging |
Het |
| Or8i2 |
A |
T |
2: 87,022,363 (GRCm38) |
Y60* |
probably null |
Het |
| Orc1 |
C |
T |
4: 108,614,459 (GRCm38) |
A836V |
probably damaging |
Het |
| Pcdhb6 |
G |
T |
18: 37,336,206 (GRCm38) |
V43L |
probably benign |
Het |
| Prkcd |
G |
T |
14: 30,599,712 (GRCm38) |
D393E |
probably benign |
Het |
| Rb1cc1 |
G |
C |
1: 6,270,690 (GRCm38) |
|
probably null |
Het |
| Rp1 |
T |
A |
1: 4,349,765 (GRCm38) |
T375S |
probably benign |
Het |
| Slc9c1 |
A |
T |
16: 45,580,219 (GRCm38) |
M731L |
probably benign |
Het |
| Sox21 |
A |
T |
14: 118,235,430 (GRCm38) |
M69K |
probably benign |
Het |
| Spata18 |
A |
T |
5: 73,666,850 (GRCm38) |
|
probably null |
Het |
| Taok1 |
A |
G |
11: 77,541,810 (GRCm38) |
F726L |
probably benign |
Het |
| Ttn |
G |
A |
2: 76,745,214 (GRCm38) |
P25112S |
probably damaging |
Het |
| Ubac1 |
C |
T |
2: 26,014,941 (GRCm38) |
R95H |
probably damaging |
Het |
| Usp32 |
A |
G |
11: 85,042,563 (GRCm38) |
Y40H |
probably damaging |
Het |
| Usp37 |
A |
T |
1: 74,492,986 (GRCm38) |
S83T |
possibly damaging |
Het |
| Vps13d |
A |
G |
4: 145,075,726 (GRCm38) |
I405T |
probably damaging |
Het |
|
| Other mutations in Mink1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00501:Mink1
|
APN |
11 |
70,603,812 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL00709:Mink1
|
APN |
11 |
70,613,019 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01064:Mink1
|
APN |
11 |
70,603,481 (GRCm38) |
missense |
probably benign |
0.05 |
|
IGL02612:Mink1
|
APN |
11 |
70,597,226 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02797:Mink1
|
APN |
11 |
70,610,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03056:Mink1
|
APN |
11 |
70,612,583 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL03066:Mink1
|
APN |
11 |
70,608,889 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03185:Mink1
|
APN |
11 |
70,603,860 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4498001:Mink1
|
UTSW |
11 |
70,598,888 (GRCm38) |
missense |
probably benign |
0.05 |
|
R0025:Mink1
|
UTSW |
11 |
70,613,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0025:Mink1
|
UTSW |
11 |
70,613,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0488:Mink1
|
UTSW |
11 |
70,597,204 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0637:Mink1
|
UTSW |
11 |
70,601,676 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0828:Mink1
|
UTSW |
11 |
70,610,145 (GRCm38) |
nonsense |
probably null |
|
|
R1081:Mink1
|
UTSW |
11 |
70,607,035 (GRCm38) |
missense |
probably benign |
0.07 |
|
R1175:Mink1
|
UTSW |
11 |
70,611,340 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1441:Mink1
|
UTSW |
11 |
70,607,114 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R1532:Mink1
|
UTSW |
11 |
70,602,007 (GRCm38) |
missense |
probably null |
1.00 |
|
R1545:Mink1
|
UTSW |
11 |
70,598,891 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R1634:Mink1
|
UTSW |
11 |
70,608,880 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1932:Mink1
|
UTSW |
11 |
70,608,428 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2033:Mink1
|
UTSW |
11 |
70,612,508 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2184:Mink1
|
UTSW |
11 |
70,603,797 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2267:Mink1
|
UTSW |
11 |
70,601,724 (GRCm38) |
splice site |
probably null |
|
|
R2268:Mink1
|
UTSW |
11 |
70,601,724 (GRCm38) |
splice site |
probably null |
|
|
R2859:Mink1
|
UTSW |
11 |
70,612,508 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3713:Mink1
|
UTSW |
11 |
70,608,950 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R3714:Mink1
|
UTSW |
11 |
70,608,950 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R3715:Mink1
|
UTSW |
11 |
70,608,950 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R3717:Mink1
|
UTSW |
11 |
70,607,761 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4607:Mink1
|
UTSW |
11 |
70,606,067 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R4735:Mink1
|
UTSW |
11 |
70,609,260 (GRCm38) |
splice site |
probably null |
|
|
R4790:Mink1
|
UTSW |
11 |
70,599,041 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4847:Mink1
|
UTSW |
11 |
70,602,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4860:Mink1
|
UTSW |
11 |
70,611,592 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4860:Mink1
|
UTSW |
11 |
70,611,592 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5081:Mink1
|
UTSW |
11 |
70,605,144 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5310:Mink1
|
UTSW |
11 |
70,607,343 (GRCm38) |
missense |
probably benign |
0.33 |
|
R5677:Mink1
|
UTSW |
11 |
70,605,165 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R5767:Mink1
|
UTSW |
11 |
70,606,075 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R5795:Mink1
|
UTSW |
11 |
70,607,790 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R5888:Mink1
|
UTSW |
11 |
70,610,059 (GRCm38) |
unclassified |
probably benign |
|
|
R5950:Mink1
|
UTSW |
11 |
70,609,586 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R6024:Mink1
|
UTSW |
11 |
70,599,089 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R6034:Mink1
|
UTSW |
11 |
70,607,040 (GRCm38) |
small deletion |
probably benign |
|
|
R6034:Mink1
|
UTSW |
11 |
70,607,040 (GRCm38) |
small deletion |
probably benign |
|
|
R6058:Mink1
|
UTSW |
11 |
70,611,720 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R6144:Mink1
|
UTSW |
11 |
70,610,652 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R6154:Mink1
|
UTSW |
11 |
70,610,101 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R6218:Mink1
|
UTSW |
11 |
70,598,894 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6262:Mink1
|
UTSW |
11 |
70,603,325 (GRCm38) |
splice site |
probably null |
|
|
R6269:Mink1
|
UTSW |
11 |
70,598,987 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6273:Mink1
|
UTSW |
11 |
70,611,435 (GRCm38) |
nonsense |
probably null |
|
|
R6301:Mink1
|
UTSW |
11 |
70,612,294 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R6603:Mink1
|
UTSW |
11 |
70,609,593 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6876:Mink1
|
UTSW |
11 |
70,607,435 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7030:Mink1
|
UTSW |
11 |
70,607,775 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7050:Mink1
|
UTSW |
11 |
70,612,332 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R7094:Mink1
|
UTSW |
11 |
70,610,075 (GRCm38) |
splice site |
probably null |
|
|
R7135:Mink1
|
UTSW |
11 |
70,603,503 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7238:Mink1
|
UTSW |
11 |
70,611,479 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7320:Mink1
|
UTSW |
11 |
70,599,073 (GRCm38) |
missense |
probably benign |
0.23 |
|
R7396:Mink1
|
UTSW |
11 |
70,605,168 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R7446:Mink1
|
UTSW |
11 |
70,609,629 (GRCm38) |
missense |
probably benign |
0.18 |
|
R7723:Mink1
|
UTSW |
11 |
70,612,910 (GRCm38) |
missense |
probably benign |
0.16 |
|
R7896:Mink1
|
UTSW |
11 |
70,612,282 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R8058:Mink1
|
UTSW |
11 |
70,603,768 (GRCm38) |
nonsense |
probably null |
|
|
R8082:Mink1
|
UTSW |
11 |
70,613,277 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R8160:Mink1
|
UTSW |
11 |
70,606,081 (GRCm38) |
nonsense |
probably null |
|
|
R8335:Mink1
|
UTSW |
11 |
70,609,575 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8353:Mink1
|
UTSW |
11 |
70,610,328 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R8453:Mink1
|
UTSW |
11 |
70,610,328 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R8732:Mink1
|
UTSW |
11 |
70,610,076 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R9072:Mink1
|
UTSW |
11 |
70,608,381 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R9073:Mink1
|
UTSW |
11 |
70,608,381 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R9324:Mink1
|
UTSW |
11 |
70,611,651 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9596:Mink1
|
UTSW |
11 |
70,607,089 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGTGTCTTCTGCGCACTAC -3'
(R):5'- ATTATCAGGCCGAACCCAGG -3'
Sequencing Primer
(F):5'- TCTTCTGCGCACTACAGGGC -3'
(R):5'- TCTGAATTCTGGCGGATGAC -3'
|
| Posted On |
2015-01-23 |
Incidental Mutation