Incidental Mutation 'R0331:Shprh'
| ID |
26068 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Shprh
|
| Ensembl Gene |
ENSMUSG00000090112 |
| Gene Name |
SNF2 histone linker PHD RING helicase |
| Synonyms |
2610103K11Rik, D230017O13Rik |
| MMRRC Submission |
038540-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0331 (G1)
|
| Quality Score |
215 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
11149427-11217595 bp(+) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 11194170 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132870
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044053]
[ENSMUST00000054814]
[ENSMUST00000159541]
|
| AlphaFold |
Q7TPQ3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000044053
|
| SMART Domains |
Protein: ENSMUSP00000039422
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
Pfam:Helicase_C
|
1500 |
1613 |
1.6e-8 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054814
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159541
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159553
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.0%
- 10x: 95.8%
- 20x: 91.7%
|
| Validation Efficiency |
100% (81/81) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700011L22Rik |
T |
A |
8: 79,229,392 (GRCm38) |
T79S |
probably benign |
Het |
| Abtb1 |
T |
C |
6: 88,840,702 (GRCm38) |
|
probably benign |
Het |
| Acot12 |
G |
A |
13: 91,760,064 (GRCm38) |
|
probably null |
Het |
| Adamts4 |
T |
A |
1: 171,250,972 (GRCm38) |
S54T |
probably benign |
Het |
| Adgrl4 |
T |
C |
3: 151,497,940 (GRCm38) |
S96P |
probably benign |
Het |
| Aip |
G |
T |
19: 4,118,247 (GRCm38) |
T40K |
probably damaging |
Het |
| Anapc4 |
A |
G |
5: 52,855,642 (GRCm38) |
|
probably benign |
Het |
| Asz1 |
A |
G |
6: 18,103,619 (GRCm38) |
|
probably benign |
Het |
| Atf7ip |
A |
G |
6: 136,561,163 (GRCm38) |
T465A |
possibly damaging |
Het |
| Atp11a |
C |
T |
8: 12,816,953 (GRCm38) |
Q127* |
probably null |
Het |
| Axin1 |
A |
G |
17: 26,143,107 (GRCm38) |
R142G |
probably damaging |
Het |
| B230359F08Rik |
A |
G |
14: 53,795,748 (GRCm38) |
N38S |
probably benign |
Het |
| Bcat1 |
T |
A |
6: 145,047,314 (GRCm38) |
E86V |
probably benign |
Het |
| Brd4 |
G |
A |
17: 32,202,515 (GRCm38) |
P749L |
probably benign |
Het |
| C1ra |
G |
A |
6: 124,519,435 (GRCm38) |
|
probably null |
Het |
| Capza2 |
A |
T |
6: 17,665,103 (GRCm38) |
N237I |
probably benign |
Het |
| Cd2ap |
A |
T |
17: 42,805,301 (GRCm38) |
V556E |
probably benign |
Het |
| Cfap65 |
G |
A |
1: 74,929,301 (GRCm38) |
P124L |
probably damaging |
Het |
| Cfap65 |
G |
T |
1: 74,929,302 (GRCm38) |
P124T |
probably damaging |
Het |
| Cftr |
T |
C |
6: 18,235,226 (GRCm38) |
V488A |
possibly damaging |
Het |
| Ckmt1 |
A |
T |
2: 121,362,856 (GRCm38) |
|
probably null |
Het |
| Cmya5 |
T |
G |
13: 93,144,403 (GRCm38) |
E35A |
possibly damaging |
Het |
| Col7a1 |
A |
G |
9: 108,967,502 (GRCm38) |
|
probably benign |
Het |
| Crmp1 |
C |
T |
5: 37,265,313 (GRCm38) |
L155F |
possibly damaging |
Het |
| Cyp2d10 |
T |
A |
15: 82,407,026 (GRCm38) |
T33S |
probably benign |
Het |
| Dhdh |
T |
C |
7: 45,488,120 (GRCm38) |
K48E |
probably benign |
Het |
| Dlst |
T |
C |
12: 85,118,812 (GRCm38) |
V103A |
probably damaging |
Het |
| Dohh |
C |
T |
10: 81,387,812 (GRCm38) |
T233I |
probably benign |
Het |
| Dvl2 |
C |
A |
11: 70,006,217 (GRCm38) |
|
probably benign |
Het |
| Eipr1 |
C |
T |
12: 28,864,704 (GRCm38) |
Q286* |
probably null |
Het |
| Enpp6 |
C |
A |
8: 47,082,449 (GRCm38) |
T343K |
probably damaging |
Het |
| Fbxw11 |
T |
A |
11: 32,711,895 (GRCm38) |
F112I |
probably damaging |
Het |
| Gdpd4 |
T |
A |
7: 97,973,008 (GRCm38) |
N231K |
probably benign |
Het |
| Gm6370 |
A |
T |
5: 146,493,766 (GRCm38) |
T254S |
probably benign |
Het |
| Hapln4 |
G |
T |
8: 70,084,509 (GRCm38) |
Q31H |
probably damaging |
Het |
| Hic1 |
T |
A |
11: 75,165,490 (GRCm38) |
T858S |
possibly damaging |
Het |
| Isg20l2 |
T |
C |
3: 87,931,785 (GRCm38) |
L101P |
probably damaging |
Het |
| Itga10 |
T |
C |
3: 96,652,483 (GRCm38) |
Y485H |
probably damaging |
Het |
| Itgal |
T |
A |
7: 127,306,681 (GRCm38) |
|
probably null |
Het |
| Itln1 |
T |
C |
1: 171,531,549 (GRCm38) |
N62S |
probably damaging |
Het |
| Kdm4b |
T |
C |
17: 56,386,289 (GRCm38) |
|
probably benign |
Het |
| Lct |
T |
C |
1: 128,298,742 (GRCm38) |
|
probably benign |
Het |
| Lman2 |
A |
T |
13: 55,353,016 (GRCm38) |
H123Q |
probably damaging |
Het |
| Lztr1 |
T |
A |
16: 17,524,237 (GRCm38) |
|
probably benign |
Het |
| Myo3b |
G |
T |
2: 70,095,261 (GRCm38) |
G24V |
probably damaging |
Het |
| Nacad |
T |
A |
11: 6,599,441 (GRCm38) |
Q1250L |
possibly damaging |
Het |
| Ncor2 |
A |
T |
5: 125,084,917 (GRCm38) |
M431K |
unknown |
Het |
| Nek9 |
T |
A |
12: 85,327,375 (GRCm38) |
|
probably benign |
Het |
| Neu1 |
C |
A |
17: 34,934,170 (GRCm38) |
N255K |
possibly damaging |
Het |
| Nf2 |
T |
A |
11: 4,794,914 (GRCm38) |
T75S |
probably benign |
Het |
| Nipal4 |
T |
A |
11: 46,150,213 (GRCm38) |
D385V |
probably damaging |
Het |
| Olah |
T |
A |
2: 3,342,474 (GRCm38) |
N245I |
probably damaging |
Het |
| Olfr474 |
G |
T |
7: 107,954,870 (GRCm38) |
L76F |
probably benign |
Het |
| Pag1 |
T |
A |
3: 9,701,970 (GRCm38) |
T90S |
probably benign |
Het |
| Pald1 |
A |
G |
10: 61,340,929 (GRCm38) |
|
probably null |
Het |
| Parva |
A |
G |
7: 112,544,798 (GRCm38) |
M98V |
probably benign |
Het |
| Paxbp1 |
T |
A |
16: 91,037,367 (GRCm38) |
D177V |
possibly damaging |
Het |
| Paxip1 |
A |
G |
5: 27,765,232 (GRCm38) |
I587T |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,680,376 (GRCm38) |
|
probably benign |
Het |
| Pdgfra |
T |
A |
5: 75,195,052 (GRCm38) |
D1074E |
probably damaging |
Het |
| Pef1 |
A |
T |
4: 130,127,448 (GRCm38) |
D265V |
probably damaging |
Het |
| Plekhh2 |
G |
A |
17: 84,586,366 (GRCm38) |
E870K |
possibly damaging |
Het |
| Plscr4 |
G |
A |
9: 92,482,642 (GRCm38) |
G40D |
probably damaging |
Het |
| Psg18 |
A |
G |
7: 18,353,308 (GRCm38) |
Y142H |
probably benign |
Het |
| Ptchd3 |
A |
T |
11: 121,842,191 (GRCm38) |
M636L |
probably benign |
Het |
| Rab2a |
A |
G |
4: 8,572,559 (GRCm38) |
D51G |
probably benign |
Het |
| Rnf139 |
T |
A |
15: 58,899,906 (GRCm38) |
D593E |
probably benign |
Het |
| Sept7 |
A |
G |
9: 25,306,256 (GRCm38) |
N422S |
probably benign |
Het |
| Slc7a6os |
A |
G |
8: 106,210,567 (GRCm38) |
I87T |
probably damaging |
Het |
| Slc7a7 |
A |
G |
14: 54,377,924 (GRCm38) |
|
probably benign |
Het |
| Spc24 |
G |
T |
9: 21,757,313 (GRCm38) |
N129K |
possibly damaging |
Het |
| Strip2 |
C |
T |
6: 29,926,560 (GRCm38) |
T148I |
probably benign |
Het |
| Tmem150c |
A |
C |
5: 100,086,273 (GRCm38) |
|
probably null |
Het |
| Ttn |
G |
T |
2: 76,811,020 (GRCm38) |
Y11801* |
probably null |
Het |
| Usp37 |
A |
T |
1: 74,454,064 (GRCm38) |
L688* |
probably null |
Het |
| Usp38 |
T |
C |
8: 80,995,840 (GRCm38) |
I351V |
probably benign |
Het |
| Vav2 |
T |
A |
2: 27,296,175 (GRCm38) |
M223L |
probably benign |
Het |
| Wdr36 |
A |
G |
18: 32,852,915 (GRCm38) |
I557M |
possibly damaging |
Het |
| Wwc2 |
A |
T |
8: 47,880,204 (GRCm38) |
M259K |
probably benign |
Het |
| Znfx1 |
G |
A |
2: 167,046,978 (GRCm38) |
S770L |
probably benign |
Het |
|
| Other mutations in Shprh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00492:Shprh
|
APN |
10 |
11,188,158 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00583:Shprh
|
APN |
10 |
11,188,020 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL00684:Shprh
|
APN |
10 |
11,163,037 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL01295:Shprh
|
APN |
10 |
11,183,868 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01387:Shprh
|
APN |
10 |
11,170,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01635:Shprh
|
APN |
10 |
11,170,019 (GRCm38) |
nonsense |
probably null |
|
|
IGL01833:Shprh
|
APN |
10 |
11,191,062 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02013:Shprh
|
APN |
10 |
11,181,502 (GRCm38) |
splice site |
probably benign |
|
|
IGL02502:Shprh
|
APN |
10 |
11,194,357 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
IGL02819:Shprh
|
APN |
10 |
11,154,765 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
PIT4581001:Shprh
|
UTSW |
10 |
11,192,494 (GRCm38) |
frame shift |
probably null |
|
|
R0010:Shprh
|
UTSW |
10 |
11,151,931 (GRCm38) |
missense |
probably benign |
|
|
R0010:Shprh
|
UTSW |
10 |
11,151,931 (GRCm38) |
missense |
probably benign |
|
|
R0053:Shprh
|
UTSW |
10 |
11,194,372 (GRCm38) |
splice site |
probably null |
|
|
R0053:Shprh
|
UTSW |
10 |
11,194,372 (GRCm38) |
splice site |
probably null |
|
|
R0255:Shprh
|
UTSW |
10 |
11,186,391 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0325:Shprh
|
UTSW |
10 |
11,170,109 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0494:Shprh
|
UTSW |
10 |
11,157,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0532:Shprh
|
UTSW |
10 |
11,162,812 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R0546:Shprh
|
UTSW |
10 |
11,183,887 (GRCm38) |
splice site |
probably benign |
|
|
R0574:Shprh
|
UTSW |
10 |
11,163,077 (GRCm38) |
unclassified |
probably benign |
|
|
R0605:Shprh
|
UTSW |
10 |
11,207,112 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0662:Shprh
|
UTSW |
10 |
11,186,847 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1148:Shprh
|
UTSW |
10 |
11,213,482 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1148:Shprh
|
UTSW |
10 |
11,213,482 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1263:Shprh
|
UTSW |
10 |
11,159,530 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1588:Shprh
|
UTSW |
10 |
11,164,744 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1638:Shprh
|
UTSW |
10 |
11,157,078 (GRCm38) |
missense |
probably benign |
|
|
R1830:Shprh
|
UTSW |
10 |
11,186,911 (GRCm38) |
splice site |
probably null |
|
|
R1898:Shprh
|
UTSW |
10 |
11,186,869 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1903:Shprh
|
UTSW |
10 |
11,183,797 (GRCm38) |
nonsense |
probably null |
|
|
R2060:Shprh
|
UTSW |
10 |
11,152,120 (GRCm38) |
missense |
probably benign |
0.03 |
|
R2225:Shprh
|
UTSW |
10 |
11,162,235 (GRCm38) |
unclassified |
probably benign |
|
|
R2363:Shprh
|
UTSW |
10 |
11,171,953 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2509:Shprh
|
UTSW |
10 |
11,166,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2891:Shprh
|
UTSW |
10 |
11,164,356 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3077:Shprh
|
UTSW |
10 |
11,170,413 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3150:Shprh
|
UTSW |
10 |
11,170,030 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3796:Shprh
|
UTSW |
10 |
11,178,757 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R4196:Shprh
|
UTSW |
10 |
11,207,860 (GRCm38) |
utr 3 prime |
probably benign |
|
|
R4423:Shprh
|
UTSW |
10 |
11,186,518 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4488:Shprh
|
UTSW |
10 |
11,160,471 (GRCm38) |
missense |
probably benign |
0.17 |
|
R4748:Shprh
|
UTSW |
10 |
11,170,476 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4768:Shprh
|
UTSW |
10 |
11,181,540 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4867:Shprh
|
UTSW |
10 |
11,164,557 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4937:Shprh
|
UTSW |
10 |
11,157,119 (GRCm38) |
missense |
probably benign |
|
|
R5140:Shprh
|
UTSW |
10 |
11,154,705 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5318:Shprh
|
UTSW |
10 |
11,166,557 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5323:Shprh
|
UTSW |
10 |
11,170,297 (GRCm38) |
splice site |
probably null |
|
|
R5450:Shprh
|
UTSW |
10 |
11,212,330 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5872:Shprh
|
UTSW |
10 |
11,188,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6030:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6030:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6392:Shprh
|
UTSW |
10 |
11,178,741 (GRCm38) |
nonsense |
probably null |
|
|
R6416:Shprh
|
UTSW |
10 |
11,167,873 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6470:Shprh
|
UTSW |
10 |
11,171,937 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6513:Shprh
|
UTSW |
10 |
11,186,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6530:Shprh
|
UTSW |
10 |
11,194,267 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6678:Shprh
|
UTSW |
10 |
11,166,545 (GRCm38) |
missense |
probably benign |
0.16 |
|
R6757:Shprh
|
UTSW |
10 |
11,181,508 (GRCm38) |
splice site |
probably null |
|
|
R6971:Shprh
|
UTSW |
10 |
11,166,693 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7158:Shprh
|
UTSW |
10 |
11,166,730 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7582:Shprh
|
UTSW |
10 |
11,164,705 (GRCm38) |
missense |
probably benign |
|
|
R7757:Shprh
|
UTSW |
10 |
11,162,180 (GRCm38) |
missense |
probably benign |
0.30 |
|
R7812:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
|
|
R7998:Shprh
|
UTSW |
10 |
11,185,341 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8061:Shprh
|
UTSW |
10 |
11,212,333 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R8082:Shprh
|
UTSW |
10 |
11,151,811 (GRCm38) |
missense |
probably benign |
0.22 |
|
R8116:Shprh
|
UTSW |
10 |
11,213,461 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8390:Shprh
|
UTSW |
10 |
11,187,983 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8445:Shprh
|
UTSW |
10 |
11,181,569 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8530:Shprh
|
UTSW |
10 |
11,151,934 (GRCm38) |
missense |
probably benign |
0.37 |
|
R8759:Shprh
|
UTSW |
10 |
11,157,164 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8937:Shprh
|
UTSW |
10 |
11,185,437 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R8995:Shprh
|
UTSW |
10 |
11,164,830 (GRCm38) |
nonsense |
probably null |
|
|
R9053:Shprh
|
UTSW |
10 |
11,154,702 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9131:Shprh
|
UTSW |
10 |
11,162,845 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R9176:Shprh
|
UTSW |
10 |
11,160,576 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9391:Shprh
|
UTSW |
10 |
11,162,889 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9423:Shprh
|
UTSW |
10 |
11,205,263 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9563:Shprh
|
UTSW |
10 |
11,166,491 (GRCm38) |
nonsense |
probably null |
|
|
R9668:Shprh
|
UTSW |
10 |
11,206,332 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9709:Shprh
|
UTSW |
10 |
11,162,830 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R9718:Shprh
|
UTSW |
10 |
11,213,504 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9750:Shprh
|
UTSW |
10 |
11,164,460 (GRCm38) |
missense |
probably damaging |
0.98 |
|
RF012:Shprh
|
UTSW |
10 |
11,164,841 (GRCm38) |
missense |
probably benign |
0.02 |
|
V8831:Shprh
|
UTSW |
10 |
11,186,862 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,186,447 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,164,553 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Shprh
|
UTSW |
10 |
11,151,762 (GRCm38) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGAGAGCCTAAAACCCATTGCC -3'
(R):5'- TACGCTCACTGTGCCAACTGTC -3'
Sequencing Primer
(F):5'- CAGTTCTGCATTATCTGCTGTTAAG -3'
(R):5'- CACAGGGATATCATCCTCTTGG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation