Incidental Mutation 'R0335:Iqgap2'
| ID |
26217 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap2
|
| Ensembl Gene |
ENSMUSG00000021676 |
| Gene Name |
IQ motif containing GTPase activating protein 2 |
| Synonyms |
4933417J23Rik |
| MMRRC Submission |
038544-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0335 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
95763685-96028788 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 95772141 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 1346
(D1346V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067685
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068603]
|
| AlphaFold |
Q3UQ44 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000068603
AA Change: D1346V
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000067685
Gene: ENSMUSG00000021676
AA Change: D1346V
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
43 |
152 |
3.32e-16 |
SMART |
|
coiled coil region
|
253 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
IQ
|
689 |
711 |
1.38e-4 |
SMART |
|
IQ
|
719 |
741 |
7.36e0 |
SMART |
|
IQ
|
749 |
771 |
2.43e1 |
SMART |
|
coiled coil region
|
799 |
828 |
N/A |
INTRINSIC |
|
RasGAP
|
905 |
1258 |
2.6e-120 |
SMART |
|
Pfam:RasGAP_C
|
1367 |
1498 |
3.2e-40 |
PFAM |
|
| Meta Mutation Damage Score |
0.3605 |
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.6%
- 10x: 94.6%
- 20x: 87.5%
|
| Validation Efficiency |
100% (89/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display reduced survival with increased incidence of hepatocellular carcinomas, increased hepatocyte apoptosis, and hepatocyte mitochondrial abnormalities. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts12 |
G |
T |
15: 11,311,144 (GRCm39) |
D1134Y |
possibly damaging |
Het |
| Add3 |
A |
G |
19: 53,225,259 (GRCm39) |
T460A |
probably benign |
Het |
| Amer3 |
A |
C |
1: 34,618,381 (GRCm39) |
|
probably benign |
Het |
| Arhgap22 |
C |
T |
14: 33,081,065 (GRCm39) |
|
probably benign |
Het |
| Arhgap32 |
T |
G |
9: 32,171,056 (GRCm39) |
S1279A |
probably benign |
Het |
| Bcas1 |
G |
A |
2: 170,260,601 (GRCm39) |
T26M |
probably damaging |
Het |
| Begain |
A |
T |
12: 109,004,860 (GRCm39) |
F256I |
probably damaging |
Het |
| Bltp1 |
T |
C |
3: 37,023,301 (GRCm39) |
V2210A |
probably damaging |
Het |
| Cabin1 |
A |
T |
10: 75,492,883 (GRCm39) |
I1804N |
probably damaging |
Het |
| Cad |
G |
A |
5: 31,231,329 (GRCm39) |
|
probably benign |
Het |
| Carmil1 |
G |
A |
13: 24,257,966 (GRCm39) |
S762L |
probably damaging |
Het |
| Ccdc93 |
T |
A |
1: 121,420,706 (GRCm39) |
L529Q |
probably damaging |
Het |
| Cdh12 |
T |
A |
15: 21,578,635 (GRCm39) |
|
probably null |
Het |
| Cep15 |
A |
G |
14: 12,301,266 (GRCm38) |
E124G |
possibly damaging |
Het |
| Clip2 |
T |
A |
5: 134,564,069 (GRCm39) |
|
probably benign |
Het |
| Cmip |
T |
C |
8: 118,172,105 (GRCm39) |
I480T |
probably damaging |
Het |
| Cnot1 |
A |
T |
8: 96,498,628 (GRCm39) |
I203K |
probably benign |
Het |
| Col18a1 |
G |
A |
10: 76,895,197 (GRCm39) |
P1155S |
probably damaging |
Het |
| Col1a2 |
T |
A |
6: 4,531,956 (GRCm39) |
|
probably benign |
Het |
| Crybg3 |
A |
T |
16: 59,364,503 (GRCm39) |
L2373Q |
probably damaging |
Het |
| D130043K22Rik |
A |
T |
13: 25,071,860 (GRCm39) |
I935F |
probably damaging |
Het |
| Dapl1 |
T |
A |
2: 59,326,938 (GRCm39) |
D61E |
possibly damaging |
Het |
| Def6 |
A |
G |
17: 28,447,043 (GRCm39) |
D558G |
possibly damaging |
Het |
| Dnah6 |
T |
C |
6: 73,046,382 (GRCm39) |
|
probably benign |
Het |
| Dvl2 |
G |
A |
11: 69,891,861 (GRCm39) |
|
probably benign |
Het |
| Ecd |
A |
C |
14: 20,370,802 (GRCm39) |
V639G |
probably benign |
Het |
| Epg5 |
C |
T |
18: 78,029,687 (GRCm39) |
T1350M |
probably benign |
Het |
| Erbb4 |
C |
A |
1: 68,298,418 (GRCm39) |
M657I |
probably benign |
Het |
| Evi5 |
T |
C |
5: 107,960,277 (GRCm39) |
R431G |
probably benign |
Het |
| Fbxo11 |
G |
A |
17: 88,323,041 (GRCm39) |
A115V |
possibly damaging |
Het |
| Fgfr2 |
T |
C |
7: 129,797,979 (GRCm39) |
T192A |
probably benign |
Het |
| Gas7 |
C |
T |
11: 67,552,878 (GRCm39) |
A146V |
possibly damaging |
Het |
| Gatad2b |
T |
A |
3: 90,263,489 (GRCm39) |
S529T |
probably benign |
Het |
| Gm10722 |
G |
T |
9: 3,001,048 (GRCm39) |
Q41H |
probably null |
Het |
| Gm10801 |
G |
C |
2: 98,494,352 (GRCm39) |
R143T |
possibly damaging |
Het |
| Gm7535 |
A |
G |
17: 18,131,374 (GRCm39) |
|
probably benign |
Het |
| Gstm1 |
T |
A |
3: 107,920,012 (GRCm39) |
N193I |
possibly damaging |
Het |
| Heatr5b |
G |
A |
17: 79,135,375 (GRCm39) |
P252L |
probably benign |
Het |
| Hmgb1 |
A |
G |
5: 148,987,441 (GRCm39) |
V36A |
probably benign |
Het |
| Hrh1 |
G |
T |
6: 114,457,193 (GRCm39) |
W158L |
probably damaging |
Het |
| Ighv6-4 |
T |
C |
12: 114,370,294 (GRCm39) |
M53V |
probably benign |
Het |
| Kcng3 |
A |
T |
17: 83,895,166 (GRCm39) |
N433K |
possibly damaging |
Het |
| Kif1a |
T |
A |
1: 92,980,288 (GRCm39) |
|
probably benign |
Het |
| Lctl |
C |
A |
9: 64,026,169 (GRCm39) |
Q75K |
probably benign |
Het |
| Ldb3 |
T |
A |
14: 34,300,608 (GRCm39) |
I89F |
possibly damaging |
Het |
| Lrrc49 |
A |
T |
9: 60,584,378 (GRCm39) |
L156Q |
probably damaging |
Het |
| Mark2 |
G |
T |
19: 7,259,193 (GRCm39) |
T83K |
probably benign |
Het |
| Ms4a15 |
A |
T |
19: 10,957,574 (GRCm39) |
D170E |
probably damaging |
Het |
| Msantd2 |
A |
G |
9: 37,434,056 (GRCm39) |
S99G |
possibly damaging |
Het |
| Nemf |
G |
T |
12: 69,400,577 (GRCm39) |
T124N |
probably benign |
Het |
| Nlrp9c |
A |
T |
7: 26,093,561 (GRCm39) |
F35I |
possibly damaging |
Het |
| Nwd2 |
A |
G |
5: 63,962,116 (GRCm39) |
I567V |
probably benign |
Het |
| Optn |
C |
T |
2: 5,028,926 (GRCm39) |
G526R |
probably damaging |
Het |
| Or11l3 |
T |
C |
11: 58,516,566 (GRCm39) |
Y102C |
probably damaging |
Het |
| Or13p8 |
A |
G |
4: 118,584,367 (GRCm39) |
I308V |
probably null |
Het |
| Or5v1b |
A |
C |
17: 37,841,533 (GRCm39) |
I222L |
probably benign |
Het |
| Or7g16 |
T |
A |
9: 18,727,290 (GRCm39) |
Q100L |
probably damaging |
Het |
| Pdk4 |
T |
C |
6: 5,491,138 (GRCm39) |
E209G |
probably benign |
Het |
| Plch1 |
T |
C |
3: 63,618,399 (GRCm39) |
Q712R |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 29,105,852 (GRCm39) |
V569E |
possibly damaging |
Het |
| Prkar2a |
A |
T |
9: 108,596,457 (GRCm39) |
D134V |
probably damaging |
Het |
| Ptov1 |
T |
A |
7: 44,514,046 (GRCm39) |
Q40L |
possibly damaging |
Het |
| Ptprq |
T |
C |
10: 107,544,589 (GRCm39) |
I314V |
probably benign |
Het |
| Rabl2 |
T |
C |
15: 89,468,169 (GRCm39) |
K66E |
probably damaging |
Het |
| Rnf38 |
A |
G |
4: 44,152,507 (GRCm39) |
V19A |
possibly damaging |
Het |
| Scn2a |
T |
A |
2: 65,512,435 (GRCm39) |
W191R |
probably damaging |
Het |
| Sec22b |
T |
A |
3: 97,828,572 (GRCm39) |
F212I |
possibly damaging |
Het |
| Sec24c |
T |
A |
14: 20,738,783 (GRCm39) |
|
probably null |
Het |
| Septin2 |
T |
C |
1: 93,423,321 (GRCm39) |
S51P |
probably damaging |
Het |
| Serpinb1a |
T |
C |
13: 33,032,639 (GRCm39) |
N90S |
probably damaging |
Het |
| Slc1a2 |
C |
T |
2: 102,574,208 (GRCm39) |
T206I |
probably benign |
Het |
| Slc25a19 |
C |
A |
11: 115,515,032 (GRCm39) |
R42L |
probably damaging |
Het |
| St14 |
G |
A |
9: 31,002,620 (GRCm39) |
|
probably benign |
Het |
| Stxbp1 |
C |
T |
2: 32,692,917 (GRCm39) |
|
probably benign |
Het |
| Tas2r131 |
C |
T |
6: 132,934,792 (GRCm39) |
V6I |
probably benign |
Het |
| Tdo2 |
T |
A |
3: 81,871,307 (GRCm39) |
M235L |
probably benign |
Het |
| Tenm3 |
T |
G |
8: 48,685,140 (GRCm39) |
H2432P |
probably damaging |
Het |
| Tmprss15 |
C |
T |
16: 78,821,630 (GRCm39) |
|
probably benign |
Het |
| Tmx1 |
A |
G |
12: 70,500,030 (GRCm39) |
N30D |
probably benign |
Het |
| Tom1 |
A |
G |
8: 75,791,020 (GRCm39) |
|
probably null |
Het |
| Top2a |
T |
C |
11: 98,913,781 (GRCm39) |
N20S |
probably benign |
Het |
| Ttc23l |
T |
A |
15: 10,540,049 (GRCm39) |
T145S |
probably benign |
Het |
| Unc13b |
T |
A |
4: 43,236,983 (GRCm39) |
M3351K |
possibly damaging |
Het |
| Vmn1r47 |
T |
C |
6: 89,999,641 (GRCm39) |
S258P |
probably damaging |
Het |
| Vmn2r8 |
T |
G |
5: 108,945,317 (GRCm39) |
|
probably null |
Het |
| Vps11 |
T |
C |
9: 44,265,135 (GRCm39) |
Q641R |
probably null |
Het |
| Wapl |
T |
A |
14: 34,414,281 (GRCm39) |
I381N |
probably damaging |
Het |
| Zmym6 |
G |
A |
4: 127,016,601 (GRCm39) |
G794E |
probably damaging |
Het |
|
| Other mutations in Iqgap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00799:Iqgap2
|
APN |
13 |
95,794,452 (GRCm39) |
splice site |
probably benign |
|
|
IGL01968:Iqgap2
|
APN |
13 |
95,772,090 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02049:Iqgap2
|
APN |
13 |
95,811,913 (GRCm39) |
splice site |
probably benign |
|
|
IGL02195:Iqgap2
|
APN |
13 |
95,798,242 (GRCm39) |
splice site |
probably benign |
|
|
IGL02387:Iqgap2
|
APN |
13 |
95,826,209 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02634:Iqgap2
|
APN |
13 |
95,764,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02666:Iqgap2
|
APN |
13 |
95,764,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02685:Iqgap2
|
APN |
13 |
95,807,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Iqgap2
|
APN |
13 |
95,861,184 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL02943:Iqgap2
|
APN |
13 |
95,798,243 (GRCm39) |
splice site |
probably benign |
|
|
IGL03167:Iqgap2
|
APN |
13 |
95,821,406 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL03169:Iqgap2
|
APN |
13 |
95,867,785 (GRCm39) |
splice site |
probably null |
|
|
IGL03293:Iqgap2
|
APN |
13 |
95,867,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
G1Funyon:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0257:Iqgap2
|
UTSW |
13 |
95,861,052 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0360:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0364:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0419:Iqgap2
|
UTSW |
13 |
95,826,207 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1229:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1290:Iqgap2
|
UTSW |
13 |
95,805,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1397:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1498:Iqgap2
|
UTSW |
13 |
95,783,313 (GRCm39) |
missense |
probably benign |
|
|
R1513:Iqgap2
|
UTSW |
13 |
95,766,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1630:Iqgap2
|
UTSW |
13 |
95,826,293 (GRCm39) |
missense |
probably benign |
|
|
R2088:Iqgap2
|
UTSW |
13 |
96,028,171 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2928:Iqgap2
|
UTSW |
13 |
95,818,744 (GRCm39) |
missense |
probably benign |
|
|
R3026:Iqgap2
|
UTSW |
13 |
95,809,564 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3720:Iqgap2
|
UTSW |
13 |
95,805,036 (GRCm39) |
splice site |
probably null |
|
|
R3846:Iqgap2
|
UTSW |
13 |
95,810,186 (GRCm39) |
splice site |
probably benign |
|
|
R4056:Iqgap2
|
UTSW |
13 |
95,886,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Iqgap2
|
UTSW |
13 |
95,794,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4353:Iqgap2
|
UTSW |
13 |
95,807,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4517:Iqgap2
|
UTSW |
13 |
95,800,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4628:Iqgap2
|
UTSW |
13 |
95,899,837 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4686:Iqgap2
|
UTSW |
13 |
95,858,117 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4724:Iqgap2
|
UTSW |
13 |
95,772,005 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4826:Iqgap2
|
UTSW |
13 |
95,899,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4847:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4967:Iqgap2
|
UTSW |
13 |
95,766,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4973:Iqgap2
|
UTSW |
13 |
95,794,305 (GRCm39) |
splice site |
probably null |
|
|
R5010:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5086:Iqgap2
|
UTSW |
13 |
95,772,088 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5496:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5512:Iqgap2
|
UTSW |
13 |
95,811,884 (GRCm39) |
nonsense |
probably null |
|
|
R5629:Iqgap2
|
UTSW |
13 |
95,768,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5830:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5831:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5832:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5833:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5834:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5888:Iqgap2
|
UTSW |
13 |
95,772,118 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5889:Iqgap2
|
UTSW |
13 |
95,768,550 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6093:Iqgap2
|
UTSW |
13 |
95,765,471 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6141:Iqgap2
|
UTSW |
13 |
95,858,194 (GRCm39) |
splice site |
probably null |
|
|
R6404:Iqgap2
|
UTSW |
13 |
95,865,985 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6434:Iqgap2
|
UTSW |
13 |
95,819,441 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6648:Iqgap2
|
UTSW |
13 |
95,818,719 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6658:Iqgap2
|
UTSW |
13 |
95,796,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6903:Iqgap2
|
UTSW |
13 |
95,797,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7223:Iqgap2
|
UTSW |
13 |
95,765,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7327:Iqgap2
|
UTSW |
13 |
95,772,163 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7371:Iqgap2
|
UTSW |
13 |
95,836,846 (GRCm39) |
splice site |
probably null |
|
|
R7378:Iqgap2
|
UTSW |
13 |
95,869,398 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7441:Iqgap2
|
UTSW |
13 |
95,764,584 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7575:Iqgap2
|
UTSW |
13 |
95,798,131 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7671:Iqgap2
|
UTSW |
13 |
95,764,627 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7713:Iqgap2
|
UTSW |
13 |
95,867,952 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7806:Iqgap2
|
UTSW |
13 |
95,818,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7893:Iqgap2
|
UTSW |
13 |
95,826,217 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8052:Iqgap2
|
UTSW |
13 |
95,794,387 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8121:Iqgap2
|
UTSW |
13 |
95,861,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8261:Iqgap2
|
UTSW |
13 |
95,772,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8301:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Iqgap2
|
UTSW |
13 |
95,798,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Iqgap2
|
UTSW |
13 |
95,796,659 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8709:Iqgap2
|
UTSW |
13 |
95,796,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8710:Iqgap2
|
UTSW |
13 |
95,796,756 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8737:Iqgap2
|
UTSW |
13 |
95,802,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8845:Iqgap2
|
UTSW |
13 |
95,794,392 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8902:Iqgap2
|
UTSW |
13 |
95,818,711 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8957:Iqgap2
|
UTSW |
13 |
95,772,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9153:Iqgap2
|
UTSW |
13 |
95,844,547 (GRCm39) |
missense |
probably benign |
|
|
R9259:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9290:Iqgap2
|
UTSW |
13 |
95,886,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9414:Iqgap2
|
UTSW |
13 |
95,783,349 (GRCm39) |
missense |
|
|
|
R9432:Iqgap2
|
UTSW |
13 |
95,774,261 (GRCm39) |
missense |
probably benign |
|
|
R9747:Iqgap2
|
UTSW |
13 |
95,821,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Iqgap2
|
UTSW |
13 |
95,807,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Iqgap2
|
UTSW |
13 |
95,867,951 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTATTCCCAGACACCTTGGCAATC -3'
(R):5'- TGGCAAGAAAACAGCACCTTTGAAC -3'
Sequencing Primer
(F):5'- CCTTGGCAATCTCGTTGAGAATG -3'
(R):5'- tgtttgtttgtttgtttgtttgttg -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation