Incidental Mutation 'R0335:Crybg3'
| ID |
26227 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Crybg3
|
| Ensembl Gene |
ENSMUSG00000022723 |
| Gene Name |
beta-gamma crystallin domain containing 3 |
| Synonyms |
|
| MMRRC Submission |
038544-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.187)
|
| Stock # |
R0335 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
59490775-59600979 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 59544140 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 2373
(L2373Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156047
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044604]
[ENSMUST00000139989]
[ENSMUST00000172910]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000044604
AA Change: L659Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000037682
Gene: ENSMUSG00000022723
AA Change: L659Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
258 |
273 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
290 |
N/A |
INTRINSIC |
|
XTALbg
|
430 |
516 |
2.78e-4 |
SMART |
|
Pfam:Crystall
|
536 |
599 |
3.3e-7 |
PFAM |
|
XTALbg
|
614 |
699 |
1.2e-21 |
SMART |
|
XTALbg
|
707 |
790 |
5.73e-19 |
SMART |
|
XTALbg
|
803 |
881 |
6.87e-5 |
SMART |
|
XTALbg
|
889 |
969 |
1.28e-7 |
SMART |
|
RICIN
|
972 |
1104 |
8.16e-14 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129350
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139989
|
| SMART Domains |
Protein: ENSMUSP00000122663
Gene: ENSMUSG00000022723
| Domain | Start | End | E-Value | Type |
|---|
|
XTALbg
|
1 |
86 |
2.15e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000172910
AA Change: L2373Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000179383
AA Change: L659Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000137452
Gene: ENSMUSG00000022723
AA Change: L659Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
390 |
405 |
N/A |
INTRINSIC |
|
low complexity region
|
414 |
422 |
N/A |
INTRINSIC |
|
XTALbg
|
562 |
648 |
2.78e-4 |
SMART |
|
Pfam:Crystall
|
668 |
731 |
1e-6 |
PFAM |
|
XTALbg
|
746 |
831 |
1.2e-21 |
SMART |
|
XTALbg
|
839 |
922 |
5.73e-19 |
SMART |
|
XTALbg
|
935 |
1013 |
6.87e-5 |
SMART |
|
XTALbg
|
1021 |
1101 |
1.28e-7 |
SMART |
|
RICIN
|
1104 |
1236 |
8.16e-14 |
SMART |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.6%
- 10x: 94.6%
- 20x: 87.5%
|
| Validation Efficiency |
100% (89/89) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3830406C13Rik |
A |
G |
14: 12,301,266 (GRCm38) |
E124G |
possibly damaging |
Het |
| 4932438A13Rik |
T |
C |
3: 36,969,152 (GRCm38) |
V2210A |
probably damaging |
Het |
| Adamts12 |
G |
T |
15: 11,311,058 (GRCm38) |
D1134Y |
possibly damaging |
Het |
| Add3 |
A |
G |
19: 53,236,828 (GRCm38) |
T460A |
probably benign |
Het |
| Amer3 |
A |
C |
1: 34,579,300 (GRCm38) |
|
probably benign |
Het |
| Arhgap22 |
C |
T |
14: 33,359,108 (GRCm38) |
|
probably benign |
Het |
| Arhgap32 |
T |
G |
9: 32,259,760 (GRCm38) |
S1279A |
probably benign |
Het |
| Bcas1 |
G |
A |
2: 170,418,681 (GRCm38) |
T26M |
probably damaging |
Het |
| Begain |
A |
T |
12: 109,038,934 (GRCm38) |
F256I |
probably damaging |
Het |
| Cabin1 |
A |
T |
10: 75,657,049 (GRCm38) |
I1804N |
probably damaging |
Het |
| Cad |
G |
A |
5: 31,073,985 (GRCm38) |
|
probably benign |
Het |
| Carmil1 |
G |
A |
13: 24,073,983 (GRCm38) |
S762L |
probably damaging |
Het |
| Ccdc93 |
T |
A |
1: 121,492,977 (GRCm38) |
L529Q |
probably damaging |
Het |
| Cdh12 |
T |
A |
15: 21,578,549 (GRCm38) |
|
probably null |
Het |
| Clip2 |
T |
A |
5: 134,535,215 (GRCm38) |
|
probably benign |
Het |
| Cmip |
T |
C |
8: 117,445,366 (GRCm38) |
I480T |
probably damaging |
Het |
| Cnot1 |
A |
T |
8: 95,772,000 (GRCm38) |
I203K |
probably benign |
Het |
| Col18a1 |
G |
A |
10: 77,059,363 (GRCm38) |
P1155S |
probably damaging |
Het |
| Col1a2 |
T |
A |
6: 4,531,956 (GRCm38) |
|
probably benign |
Het |
| D130043K22Rik |
A |
T |
13: 24,887,877 (GRCm38) |
I935F |
probably damaging |
Het |
| Dapl1 |
T |
A |
2: 59,496,594 (GRCm38) |
D61E |
possibly damaging |
Het |
| Def6 |
A |
G |
17: 28,228,069 (GRCm38) |
D558G |
possibly damaging |
Het |
| Dnah6 |
T |
C |
6: 73,069,399 (GRCm38) |
|
probably benign |
Het |
| Dvl2 |
G |
A |
11: 70,001,035 (GRCm38) |
|
probably benign |
Het |
| Ecd |
A |
C |
14: 20,320,734 (GRCm38) |
V639G |
probably benign |
Het |
| Epg5 |
C |
T |
18: 77,986,472 (GRCm38) |
T1350M |
probably benign |
Het |
| Erbb4 |
C |
A |
1: 68,259,259 (GRCm38) |
M657I |
probably benign |
Het |
| Evi5 |
T |
C |
5: 107,812,411 (GRCm38) |
R431G |
probably benign |
Het |
| Fbxo11 |
G |
A |
17: 88,015,613 (GRCm38) |
A115V |
possibly damaging |
Het |
| Fgfr2 |
T |
C |
7: 130,196,249 (GRCm38) |
T192A |
probably benign |
Het |
| Gas7 |
C |
T |
11: 67,662,052 (GRCm38) |
A146V |
possibly damaging |
Het |
| Gatad2b |
T |
A |
3: 90,356,182 (GRCm38) |
S529T |
probably benign |
Het |
| Gm10722 |
G |
T |
9: 3,001,048 (GRCm38) |
Q41H |
probably null |
Het |
| Gm10801 |
G |
C |
2: 98,664,007 (GRCm38) |
R143T |
possibly damaging |
Het |
| Gm7535 |
A |
G |
17: 17,911,112 (GRCm38) |
|
probably benign |
Het |
| Gstm1 |
T |
A |
3: 108,012,696 (GRCm38) |
N193I |
possibly damaging |
Het |
| Heatr5b |
G |
A |
17: 78,827,946 (GRCm38) |
P252L |
probably benign |
Het |
| Hmgb1 |
A |
G |
5: 149,050,631 (GRCm38) |
V36A |
probably benign |
Het |
| Hrh1 |
G |
T |
6: 114,480,232 (GRCm38) |
W158L |
probably damaging |
Het |
| Ighv6-4 |
T |
C |
12: 114,406,674 (GRCm38) |
M53V |
probably benign |
Het |
| Iqgap2 |
T |
A |
13: 95,635,633 (GRCm38) |
D1346V |
probably damaging |
Het |
| Kcng3 |
A |
T |
17: 83,587,737 (GRCm38) |
N433K |
possibly damaging |
Het |
| Kif1a |
T |
A |
1: 93,052,566 (GRCm38) |
|
probably benign |
Het |
| Lctl |
C |
A |
9: 64,118,887 (GRCm38) |
Q75K |
probably benign |
Het |
| Ldb3 |
T |
A |
14: 34,578,651 (GRCm38) |
I89F |
possibly damaging |
Het |
| Lrrc49 |
A |
T |
9: 60,677,095 (GRCm38) |
L156Q |
probably damaging |
Het |
| Mark2 |
G |
T |
19: 7,281,828 (GRCm38) |
T83K |
probably benign |
Het |
| Ms4a15 |
A |
T |
19: 10,980,210 (GRCm38) |
D170E |
probably damaging |
Het |
| Msantd2 |
A |
G |
9: 37,522,760 (GRCm38) |
S99G |
possibly damaging |
Het |
| Nemf |
G |
T |
12: 69,353,803 (GRCm38) |
T124N |
probably benign |
Het |
| Nlrp9c |
A |
T |
7: 26,394,136 (GRCm38) |
F35I |
possibly damaging |
Het |
| Nwd2 |
A |
G |
5: 63,804,773 (GRCm38) |
I567V |
probably benign |
Het |
| Olfr111 |
A |
C |
17: 37,530,642 (GRCm38) |
I222L |
probably benign |
Het |
| Olfr1340 |
A |
G |
4: 118,727,170 (GRCm38) |
I308V |
probably null |
Het |
| Olfr323 |
T |
C |
11: 58,625,740 (GRCm38) |
Y102C |
probably damaging |
Het |
| Olfr828 |
T |
A |
9: 18,815,994 (GRCm38) |
Q100L |
probably damaging |
Het |
| Optn |
C |
T |
2: 5,024,115 (GRCm38) |
G526R |
probably damaging |
Het |
| Pdk4 |
T |
C |
6: 5,491,138 (GRCm38) |
E209G |
probably benign |
Het |
| Plch1 |
T |
C |
3: 63,710,978 (GRCm38) |
Q712R |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 28,886,878 (GRCm38) |
V569E |
possibly damaging |
Het |
| Prkar2a |
A |
T |
9: 108,719,258 (GRCm38) |
D134V |
probably damaging |
Het |
| Ptov1 |
T |
A |
7: 44,864,622 (GRCm38) |
Q40L |
possibly damaging |
Het |
| Ptprq |
T |
C |
10: 107,708,728 (GRCm38) |
I314V |
probably benign |
Het |
| Rabl2 |
T |
C |
15: 89,583,966 (GRCm38) |
K66E |
probably damaging |
Het |
| Rnf38 |
A |
G |
4: 44,152,507 (GRCm38) |
V19A |
possibly damaging |
Het |
| Scn2a |
T |
A |
2: 65,682,091 (GRCm38) |
W191R |
probably damaging |
Het |
| Sec22b |
T |
A |
3: 97,921,256 (GRCm38) |
F212I |
possibly damaging |
Het |
| Sec24c |
T |
A |
14: 20,688,715 (GRCm38) |
|
probably null |
Het |
| Sept2 |
T |
C |
1: 93,495,599 (GRCm38) |
S51P |
probably damaging |
Het |
| Serpinb1a |
T |
C |
13: 32,848,656 (GRCm38) |
N90S |
probably damaging |
Het |
| Slc1a2 |
C |
T |
2: 102,743,863 (GRCm38) |
T206I |
probably benign |
Het |
| Slc25a19 |
C |
A |
11: 115,624,206 (GRCm38) |
R42L |
probably damaging |
Het |
| St14 |
G |
A |
9: 31,091,324 (GRCm38) |
|
probably benign |
Het |
| Stxbp1 |
C |
T |
2: 32,802,905 (GRCm38) |
|
probably benign |
Het |
| Tas2r131 |
C |
T |
6: 132,957,829 (GRCm38) |
V6I |
probably benign |
Het |
| Tdo2 |
T |
A |
3: 81,964,000 (GRCm38) |
M235L |
probably benign |
Het |
| Tenm3 |
T |
G |
8: 48,232,105 (GRCm38) |
H2432P |
probably damaging |
Het |
| Tmprss15 |
C |
T |
16: 79,024,742 (GRCm38) |
|
probably benign |
Het |
| Tmx1 |
A |
G |
12: 70,453,256 (GRCm38) |
N30D |
probably benign |
Het |
| Tom1 |
A |
G |
8: 75,064,392 (GRCm38) |
|
probably null |
Het |
| Top2a |
T |
C |
11: 99,022,955 (GRCm38) |
N20S |
probably benign |
Het |
| Ttc23l |
T |
A |
15: 10,539,963 (GRCm38) |
T145S |
probably benign |
Het |
| Unc13b |
T |
A |
4: 43,236,983 (GRCm38) |
M3351K |
possibly damaging |
Het |
| Vmn1r47 |
T |
C |
6: 90,022,659 (GRCm38) |
S258P |
probably damaging |
Het |
| Vmn2r8 |
T |
G |
5: 108,797,451 (GRCm38) |
|
probably null |
Het |
| Vps11 |
T |
C |
9: 44,353,838 (GRCm38) |
Q641R |
probably null |
Het |
| Wapl |
T |
A |
14: 34,692,324 (GRCm38) |
I381N |
probably damaging |
Het |
| Zmym6 |
G |
A |
4: 127,122,808 (GRCm38) |
G794E |
probably damaging |
Het |
|
| Other mutations in Crybg3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00516:Crybg3
|
APN |
16 |
59,530,440 (GRCm38) |
missense |
probably benign |
0.15 |
|
IGL01305:Crybg3
|
APN |
16 |
59,529,227 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01809:Crybg3
|
APN |
16 |
59,524,853 (GRCm38) |
critical splice donor site |
probably benign |
0.00 |
|
IGL02247:Crybg3
|
APN |
16 |
59,503,150 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02252:Crybg3
|
APN |
16 |
59,552,524 (GRCm38) |
splice site |
probably benign |
|
|
IGL03036:Crybg3
|
APN |
16 |
59,555,179 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
IGL03202:Crybg3
|
APN |
16 |
59,494,709 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03232:Crybg3
|
APN |
16 |
59,530,368 (GRCm38) |
missense |
probably damaging |
1.00 |
|
ANU22:Crybg3
|
UTSW |
16 |
59,529,227 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0052:Crybg3
|
UTSW |
16 |
59,565,656 (GRCm38) |
splice site |
probably benign |
|
|
R0691:Crybg3
|
UTSW |
16 |
59,565,211 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1511:Crybg3
|
UTSW |
16 |
59,554,112 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1579:Crybg3
|
UTSW |
16 |
59,530,198 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1965:Crybg3
|
UTSW |
16 |
59,503,237 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1982:Crybg3
|
UTSW |
16 |
59,544,125 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R2225:Crybg3
|
UTSW |
16 |
59,554,678 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4074:Crybg3
|
UTSW |
16 |
59,555,757 (GRCm38) |
unclassified |
probably benign |
|
|
R4210:Crybg3
|
UTSW |
16 |
59,544,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4393:Crybg3
|
UTSW |
16 |
59,560,095 (GRCm38) |
unclassified |
probably benign |
|
|
R4394:Crybg3
|
UTSW |
16 |
59,560,095 (GRCm38) |
unclassified |
probably benign |
|
|
R4397:Crybg3
|
UTSW |
16 |
59,560,095 (GRCm38) |
unclassified |
probably benign |
|
|
R4427:Crybg3
|
UTSW |
16 |
59,543,199 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4578:Crybg3
|
UTSW |
16 |
59,530,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4720:Crybg3
|
UTSW |
16 |
59,539,817 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4917:Crybg3
|
UTSW |
16 |
59,530,419 (GRCm38) |
missense |
probably benign |
0.14 |
|
R5007:Crybg3
|
UTSW |
16 |
59,558,100 (GRCm38) |
unclassified |
probably benign |
|
|
R5020:Crybg3
|
UTSW |
16 |
59,554,796 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R5155:Crybg3
|
UTSW |
16 |
59,524,901 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5306:Crybg3
|
UTSW |
16 |
59,559,993 (GRCm38) |
unclassified |
probably benign |
|
|
R5342:Crybg3
|
UTSW |
16 |
59,522,149 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5687:Crybg3
|
UTSW |
16 |
59,559,166 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5763:Crybg3
|
UTSW |
16 |
59,554,610 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R5860:Crybg3
|
UTSW |
16 |
59,565,269 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5950:Crybg3
|
UTSW |
16 |
59,493,571 (GRCm38) |
unclassified |
probably benign |
|
|
R6007:Crybg3
|
UTSW |
16 |
59,554,474 (GRCm38) |
nonsense |
probably null |
|
|
R6042:Crybg3
|
UTSW |
16 |
59,550,475 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R6049:Crybg3
|
UTSW |
16 |
59,544,054 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6242:Crybg3
|
UTSW |
16 |
59,555,690 (GRCm38) |
missense |
probably benign |
|
|
R6301:Crybg3
|
UTSW |
16 |
59,530,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6408:Crybg3
|
UTSW |
16 |
59,495,690 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R6724:Crybg3
|
UTSW |
16 |
59,544,138 (GRCm38) |
missense |
probably benign |
0.13 |
|
R6745:Crybg3
|
UTSW |
16 |
59,552,244 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R6777:Crybg3
|
UTSW |
16 |
59,558,315 (GRCm38) |
unclassified |
probably benign |
|
|
R6843:Crybg3
|
UTSW |
16 |
59,559,796 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6914:Crybg3
|
UTSW |
16 |
59,539,820 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R6942:Crybg3
|
UTSW |
16 |
59,539,820 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7033:Crybg3
|
UTSW |
16 |
59,554,165 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7091:Crybg3
|
UTSW |
16 |
59,557,168 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R7133:Crybg3
|
UTSW |
16 |
59,536,804 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7193:Crybg3
|
UTSW |
16 |
59,559,593 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R7204:Crybg3
|
UTSW |
16 |
59,558,890 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7398:Crybg3
|
UTSW |
16 |
59,557,325 (GRCm38) |
missense |
probably benign |
0.38 |
|
R7666:Crybg3
|
UTSW |
16 |
59,559,337 (GRCm38) |
nonsense |
probably null |
|
|
R7691:Crybg3
|
UTSW |
16 |
59,556,134 (GRCm38) |
missense |
not run |
|
|
R7714:Crybg3
|
UTSW |
16 |
59,558,873 (GRCm38) |
missense |
probably benign |
0.19 |
|
R7860:Crybg3
|
UTSW |
16 |
59,555,242 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7901:Crybg3
|
UTSW |
16 |
59,557,544 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8371:Crybg3
|
UTSW |
16 |
59,557,051 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8394:Crybg3
|
UTSW |
16 |
59,558,288 (GRCm38) |
missense |
probably benign |
0.06 |
|
R8438:Crybg3
|
UTSW |
16 |
59,565,292 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8529:Crybg3
|
UTSW |
16 |
59,556,621 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8699:Crybg3
|
UTSW |
16 |
59,554,928 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8766:Crybg3
|
UTSW |
16 |
59,555,333 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8767:Crybg3
|
UTSW |
16 |
59,556,137 (GRCm38) |
missense |
probably benign |
|
|
R8789:Crybg3
|
UTSW |
16 |
59,554,996 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8871:Crybg3
|
UTSW |
16 |
59,558,156 (GRCm38) |
missense |
probably benign |
|
|
R8878:Crybg3
|
UTSW |
16 |
59,560,184 (GRCm38) |
missense |
probably benign |
0.09 |
|
R8894:Crybg3
|
UTSW |
16 |
59,522,189 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8928:Crybg3
|
UTSW |
16 |
59,556,352 (GRCm38) |
missense |
probably benign |
0.40 |
|
R8928:Crybg3
|
UTSW |
16 |
59,494,760 (GRCm38) |
missense |
probably benign |
0.31 |
|
R8939:Crybg3
|
UTSW |
16 |
59,556,149 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9010:Crybg3
|
UTSW |
16 |
59,554,339 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9266:Crybg3
|
UTSW |
16 |
59,552,181 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9348:Crybg3
|
UTSW |
16 |
59,600,893 (GRCm38) |
start codon destroyed |
probably null |
0.66 |
|
R9353:Crybg3
|
UTSW |
16 |
59,600,744 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9406:Crybg3
|
UTSW |
16 |
59,558,476 (GRCm38) |
missense |
probably benign |
0.42 |
|
R9429:Crybg3
|
UTSW |
16 |
59,555,193 (GRCm38) |
missense |
probably benign |
0.08 |
|
R9464:Crybg3
|
UTSW |
16 |
59,555,757 (GRCm38) |
unclassified |
probably benign |
|
|
R9621:Crybg3
|
UTSW |
16 |
59,506,250 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R9703:Crybg3
|
UTSW |
16 |
59,555,576 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9751:Crybg3
|
UTSW |
16 |
59,557,524 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R9766:Crybg3
|
UTSW |
16 |
59,555,844 (GRCm38) |
missense |
probably benign |
0.03 |
|
RF007:Crybg3
|
UTSW |
16 |
59,556,704 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
Z1177:Crybg3
|
UTSW |
16 |
59,556,478 (GRCm38) |
missense |
probably benign |
0.09 |
|
Z1177:Crybg3
|
UTSW |
16 |
59,555,393 (GRCm38) |
nonsense |
probably null |
|
|
Z1187:Crybg3
|
UTSW |
16 |
59,506,245 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCTGCTCCTGGAAGTCATACATC -3'
(R):5'- GGCGTTGTTCTTGTGGAGAAATCCC -3'
Sequencing Primer
(F):5'- GGAATCTGTTTTAAGCCAGGAAGTC -3'
(R):5'- TTTACAACACCAGCCCTGTG -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation