Incidental Mutation 'R1261:Dnajc9'
ID262743
Institutional Source Beutler Lab
Gene Symbol Dnajc9
Ensembl Gene ENSMUSG00000021811
Gene NameDnaJ heat shock protein family (Hsp40) member C9
Synonyms
MMRRC Submission 039328-MU
Accession Numbers
Is this an essential gene? Essential (E-score: 1.000) question?
Stock #R1261 (G1)
Quality Score137
Status Not validated
Chromosome14
Chromosomal Location20384638-20388910 bp(-) (GRCm38)
Type of Mutationsplice site (607 bp from exon)
DNA Base Change (assembly) G to A at 20388697 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000055619 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000022345] [ENSMUST00000061444]
Predicted Effect probably null
Transcript: ENSMUST00000022345
SMART Domains Protein: ENSMUSP00000022345
Gene: ENSMUSG00000021811

DomainStartEndE-ValueType
DnaJ 14 74 2.76e-16 SMART
coiled coil region 176 212 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000061444
SMART Domains Protein: ENSMUSP00000055619
Gene: ENSMUSG00000049960

DomainStartEndE-ValueType
Pfam:Ribosomal_S16 24 84 9.9e-25 PFAM
low complexity region 107 135 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000223844
Predicted Effect noncoding transcript
Transcript: ENSMUST00000223889
Predicted Effect noncoding transcript
Transcript: ENSMUST00000223950
Predicted Effect noncoding transcript
Transcript: ENSMUST00000224286
Coding Region Coverage
  • 1x: 99.0%
  • 3x: 98.2%
  • 10x: 96.1%
  • 20x: 92.0%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 19 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aak1 T C 6: 86,935,488 V114A probably benign Het
Arhgef38 T C 3: 133,160,863 E171G possibly damaging Het
Arsi A G 18: 60,916,671 T209A probably damaging Het
BC005561 A G 5: 104,520,635 T1008A probably damaging Het
Bmp3 A T 5: 98,879,926 R468S probably damaging Het
Cenpk T A 13: 104,230,785 V43E possibly damaging Het
Chmp7 C T 14: 69,719,450 M336I probably benign Het
Cul9 G T 17: 46,525,782 L1106M probably damaging Het
Enpp3 A T 10: 24,774,934 V768E probably damaging Het
Klk5 T C 7: 43,845,290 S66P probably damaging Het
Lrriq1 T C 10: 103,234,137 D6G possibly damaging Het
Myh7b A G 2: 155,621,083 K453R probably benign Het
Nipsnap3b G T 4: 53,015,166 G71V probably damaging Het
Oas1h A G 5: 120,871,867 E335G probably benign Het
Olfr1002 A C 2: 85,647,799 I174S probably damaging Het
Rfwd3 C T 8: 111,288,242 R326Q probably damaging Het
Slc10a1 T A 12: 80,967,830 M39L probably damaging Het
Tas1r2 G A 4: 139,655,288 R79Q probably damaging Het
Tmprss11d T C 5: 86,309,380 D140G possibly damaging Het
Other mutations in Dnajc9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00923:Dnajc9 APN 14 20385447 missense probably benign 0.01
IGL01631:Dnajc9 APN 14 20388108 missense probably benign 0.02
R1257:Dnajc9 UTSW 14 20388697 splice site probably null
R1258:Dnajc9 UTSW 14 20388697 splice site probably null
R1765:Dnajc9 UTSW 14 20388090 missense possibly damaging 0.73
R1835:Dnajc9 UTSW 14 20388334 missense possibly damaging 0.89
R7218:Dnajc9 UTSW 14 20388439 missense probably benign 0.02
R7570:Dnajc9 UTSW 14 20388644 missense probably benign 0.01
R7600:Dnajc9 UTSW 14 20388725 missense probably damaging 1.00
R7960:Dnajc9 UTSW 14 20388696 missense possibly damaging 0.90
Predicted Primers
Posted On2015-02-04