Incidental Mutation 'R1522:Olfr1302'
ID 262822
Institutional Source Beutler Lab
Gene Symbol Olfr1302
Ensembl Gene ENSMUSG00000044560
Gene Name olfactory receptor 1302
Synonyms MOR248-3, GA_x6K02T2Q125-72831562-72832500
MMRRC Submission 040871-MU
Accession Numbers
Essential gene? Probably non essential (E-score: 0.070) question?
Stock # R1522 (G1)
Quality Score 225
Status Not validated
Chromosome 2
Chromosomal Location 111777429-111782700 bp(+) (GRCm38)
Type of Mutation splice site
DNA Base Change (assembly) A to T at 111780348 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000061674 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000054004] [ENSMUST00000119566] [ENSMUST00000214708] [ENSMUST00000215244]
AlphaFold Q8VGE9
Predicted Effect probably null
Transcript: ENSMUST00000054004
SMART Domains Protein: ENSMUSP00000061674
Gene: ENSMUSG00000044560

Pfam:7tm_4 34 308 2.4e-49 PFAM
Pfam:7tm_1 44 290 8.1e-19 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000119566
Predicted Effect silent
Transcript: ENSMUST00000214708
Predicted Effect silent
Transcript: ENSMUST00000215244
Coding Region Coverage
  • 1x: 99.0%
  • 3x: 98.1%
  • 10x: 95.8%
  • 20x: 91.1%
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 99 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700003E16Rik T C 6: 83,162,586 (GRCm38) S498P probably damaging Het
3100002H09Rik A G 4: 124,610,694 (GRCm38) W22R probably damaging Het
AA986860 A G 1: 130,743,094 (GRCm38) E351G probably damaging Het
Acsl5 T C 19: 55,280,492 (GRCm38) V195A probably benign Het
Adamts10 A G 17: 33,537,319 (GRCm38) D312G probably benign Het
Adgrb1 A G 15: 74,580,617 (GRCm38) M211V probably damaging Het
Ankfy1 C T 11: 72,755,867 (GRCm38) R859* probably null Het
Atp8b1 T A 18: 64,550,432 (GRCm38) I742L probably benign Het
B3galnt2 T A 13: 13,970,769 (GRCm38) V89E probably damaging Het
BC024978 A G 7: 27,202,680 (GRCm38) H244R probably damaging Het
Brinp3 A C 1: 146,901,890 (GRCm38) T692P probably damaging Het
C9 T A 15: 6,486,762 (GRCm38) F349I probably damaging Het
Cacna1a T A 8: 84,633,433 (GRCm38) M1976K probably benign Het
Ccdc180 T C 4: 45,927,975 (GRCm38) V1170A possibly damaging Het
Celsr1 A G 15: 85,931,276 (GRCm38) V1846A probably benign Het
Ces1f A T 8: 93,271,889 (GRCm38) Y160N possibly damaging Het
Cfap45 A G 1: 172,540,572 (GRCm38) E377G probably damaging Het
Clca3a1 T A 3: 144,755,171 (GRCm38) M240L probably benign Het
Clnk G A 5: 38,794,966 (GRCm38) T10M probably damaging Het
Cntrl T A 2: 35,155,279 (GRCm38) I781K possibly damaging Het
Col11a2 G A 17: 34,055,254 (GRCm38) G375S probably damaging Het
Col6a5 T A 9: 105,939,994 (GRCm38) I373F unknown Het
Dmxl1 C T 18: 49,852,367 (GRCm38) A227V probably benign Het
Dok5 A G 2: 170,732,132 (GRCm38) N4D probably benign Het
Dpysl3 A T 18: 43,363,557 (GRCm38) V138D probably damaging Het
Efs A T 14: 54,919,715 (GRCm38) Y380N probably damaging Het
Eme2 G A 17: 24,892,918 (GRCm38) S263F probably damaging Het
Farp2 A G 1: 93,618,553 (GRCm38) Q855R possibly damaging Het
Fcrls A C 3: 87,256,707 (GRCm38) S372A possibly damaging Het
Gadl1 C T 9: 115,944,229 (GRCm38) A113V probably damaging Het
Gatsl2 T G 5: 134,125,887 (GRCm38) S43R probably damaging Het
Gda T A 19: 21,412,539 (GRCm38) E219D probably benign Het
Gli1 A T 10: 127,332,577 (GRCm38) M469K probably damaging Het
Gm4847 A T 1: 166,641,650 (GRCm38) S148R probably damaging Het
Golga2 T C 2: 32,302,204 (GRCm38) V325A probably benign Het
Hpf1 A G 8: 60,896,749 (GRCm38) D137G probably damaging Het
Htr2a C G 14: 74,705,853 (GRCm38) S291* probably null Het
Itga5 G A 15: 103,356,782 (GRCm38) Q233* probably null Het
Jazf1 C A 6: 52,812,183 (GRCm38) R102L probably damaging Het
Kif6 T G 17: 49,714,113 (GRCm38) L322R probably damaging Het
Ktn1 A C 14: 47,667,416 (GRCm38) K217T probably damaging Het
Lig4 A T 8: 9,973,012 (GRCm38) V256E possibly damaging Het
Lrp1 A T 10: 127,575,286 (GRCm38) D1399E probably benign Het
Lrp1 G T 10: 127,567,364 (GRCm38) D2113E probably damaging Het
Mmel1 A G 4: 154,894,986 (GRCm38) E717G probably damaging Het
Mndal G T 1: 173,871,466 (GRCm38) P155H possibly damaging Het
Mycbpap A G 11: 94,511,623 (GRCm38) probably null Het
Nedd1 T C 10: 92,719,614 (GRCm38) E3G probably damaging Het
Nlgn1 A T 3: 25,435,909 (GRCm38) N551K probably damaging Het
Nup210 G A 6: 91,069,166 (GRCm38) P595L possibly damaging Het
Olfr117 A T 17: 37,659,770 (GRCm38) C188S probably damaging Het
Olfr199 T G 16: 59,215,984 (GRCm38) T210P probably damaging Het
Olfr477 A G 7: 107,990,533 (GRCm38) H56R probably benign Het
Olfr697 A G 7: 106,741,005 (GRCm38) C310R probably benign Het
Pank3 G A 11: 35,781,681 (GRCm38) V304M probably benign Het
Phf3 G A 1: 30,805,648 (GRCm38) T1410I probably benign Het
Ppm1k A G 6: 57,525,157 (GRCm38) I7T possibly damaging Het
Ppp1r12c T C 7: 4,497,425 (GRCm38) D73G probably damaging Het
Prelid2 T G 18: 41,881,267 (GRCm38) M165L probably benign Het
Prkd3 A C 17: 78,952,696 (GRCm38) L826R probably damaging Het
Ptchd4 A T 17: 42,503,542 (GRCm38) N778I probably damaging Het
Ptprm T C 17: 66,693,871 (GRCm38) D1063G possibly damaging Het
Rab27a C A 9: 73,075,482 (GRCm38) T23N probably damaging Het
Rasgrf2 A T 13: 91,896,086 (GRCm38) F949L probably benign Het
Rbm33 A G 5: 28,337,004 (GRCm38) N68D probably damaging Het
Rgl1 A T 1: 152,586,533 (GRCm38) L109Q probably damaging Het
Rnf20 A G 4: 49,638,197 (GRCm38) N103S possibly damaging Het
Sbno1 G A 5: 124,392,612 (GRCm38) L875F probably damaging Het
Scube1 T A 15: 83,628,076 (GRCm38) probably null Het
Selenbp1 G A 3: 94,937,358 (GRCm38) V109M probably damaging Het
Serpina3c T A 12: 104,151,546 (GRCm38) I178F probably damaging Het
Shisa8 C T 15: 82,208,501 (GRCm38) G63D probably damaging Het
Snx14 T C 9: 88,402,224 (GRCm38) R464G possibly damaging Het
Snx25 A T 8: 46,124,082 (GRCm38) M1K probably null Het
Sorcs3 C A 19: 48,706,009 (GRCm38) T574K possibly damaging Het
Syne2 A G 12: 76,103,783 (GRCm38) E6528G probably damaging Het
Syt5 T C 7: 4,540,246 (GRCm38) E338G probably damaging Het
Tbk1 T C 10: 121,551,318 (GRCm38) K691E probably benign Het
Tenm3 G A 8: 48,395,576 (GRCm38) T11I probably damaging Het
Thrb A G 14: 18,002,597 (GRCm38) H87R probably damaging Het
Tlr4 T A 4: 66,839,696 (GRCm38) M242K possibly damaging Het
Tm4sf19 T C 16: 32,406,002 (GRCm38) M56T possibly damaging Het
Tmem212 T A 3: 27,886,471 (GRCm38) R66* probably null Het
Tmem39b G T 4: 129,684,482 (GRCm38) D315E probably benign Het
Tnxb T C 17: 34,718,638 (GRCm38) F3834L probably damaging Het
Trim36 A T 18: 46,186,183 (GRCm38) L225* probably null Het
Trim42 A T 9: 97,365,679 (GRCm38) H321Q probably damaging Het
Trio G T 15: 27,732,640 (GRCm38) Q3052K probably benign Het
Trpm3 T C 19: 22,978,334 (GRCm38) I1091T probably benign Het
Tst T C 15: 78,399,943 (GRCm38) E228G possibly damaging Het
Ttn T C 2: 76,871,716 (GRCm38) probably benign Het
Uap1 A C 1: 170,150,941 (GRCm38) probably null Het
Ush2a T C 1: 188,797,814 (GRCm38) S3267P possibly damaging Het
Usp5 T C 6: 124,825,166 (GRCm38) T38A probably benign Het
Uvssa A T 5: 33,387,808 (GRCm38) Q84L probably damaging Het
Vmn1r159 T G 7: 22,843,268 (GRCm38) H113P probably damaging Het
Vps13d A T 4: 145,098,172 (GRCm38) probably null Het
Zfp182 T A X: 21,031,560 (GRCm38) I166L probably benign Het
Zfp811 A T 17: 32,797,648 (GRCm38) Y472N probably damaging Het
Other mutations in Olfr1302
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01354:Olfr1302 APN 2 111,780,901 (GRCm38) missense possibly damaging 0.80
IGL01604:Olfr1302 APN 2 111,780,590 (GRCm38) missense possibly damaging 0.60
IGL02959:Olfr1302 APN 2 111,780,610 (GRCm38) missense probably damaging 1.00
IGL02975:Olfr1302 APN 2 111,780,921 (GRCm38) nonsense probably null
IGL03357:Olfr1302 APN 2 111,780,526 (GRCm38) missense probably benign 0.01
R0245:Olfr1302 UTSW 2 111,780,335 (GRCm38) missense probably damaging 1.00
R2126:Olfr1302 UTSW 2 111,780,496 (GRCm38) missense probably damaging 0.99
R2432:Olfr1302 UTSW 2 111,780,671 (GRCm38) missense probably benign 0.01
R4780:Olfr1302 UTSW 2 111,780,845 (GRCm38) missense probably damaging 1.00
R5260:Olfr1302 UTSW 2 111,781,181 (GRCm38) missense probably damaging 1.00
R5517:Olfr1302 UTSW 2 111,780,459 (GRCm38) missense probably benign
R6273:Olfr1302 UTSW 2 111,781,222 (GRCm38) missense probably benign 0.00
R7315:Olfr1302 UTSW 2 111,780,659 (GRCm38) missense probably damaging 0.96
R7740:Olfr1302 UTSW 2 111,780,448 (GRCm38) missense possibly damaging 0.94
R8742:Olfr1302 UTSW 2 111,780,565 (GRCm38) missense probably benign 0.03
R8891:Olfr1302 UTSW 2 111,780,841 (GRCm38) missense probably damaging 0.99
Predicted Primers
Posted On 2015-02-04