Incidental Mutation 'IGL00487:Dusp23'
ID26569
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Dusp23
Ensembl Gene ENSMUSG00000026544
Gene Namedual specificity phosphatase 23
SynonymsLdp-3, 1300005N15Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.073) question?
Stock #IGL00487
Quality Score
Status
Chromosome1
Chromosomal Location172630764-172632962 bp(-) (GRCm38)
Type of Mutationutr 3 prime
DNA Base Change (assembly) T to C at 172631632 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000027826 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000027826]
Predicted Effect probably benign
Transcript: ENSMUST00000027826
SMART Domains Protein: ENSMUSP00000027826
Gene: ENSMUSG00000026544

DomainStartEndE-ValueType
Pfam:DSPc 26 148 1e-14 PFAM
Pfam:Y_phosphatase 36 147 7.6e-10 PFAM
Pfam:PTPlike_phytase 48 112 3.1e-14 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 15 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca5 T A 11: 110,309,450 probably null Het
Invs C T 4: 48,407,689 Q555* probably null Het
Mak16 T C 8: 31,166,750 N9D probably benign Het
Mrps7 T C 11: 115,604,858 I74T possibly damaging Het
Nlrp4a T G 7: 26,449,985 V339G possibly damaging Het
Nucb1 A G 7: 45,501,651 L102P probably damaging Het
Pdp2 T C 8: 104,594,197 M226T probably benign Het
Pik3r2 T C 8: 70,770,429 D449G probably damaging Het
Rnf157 G A 11: 116,362,355 P76S probably benign Het
Senp6 C A 9: 80,113,838 Q267K probably damaging Het
Slc9a2 A G 1: 40,742,658 E349G probably damaging Het
Snx14 G T 9: 88,402,190 S475Y probably damaging Het
Vmn1r180 A T 7: 23,952,523 H37L probably benign Het
Wdr66 T G 5: 123,274,177 I84S probably damaging Het
Xrn1 A T 9: 96,038,949 H1371L probably benign Het
Other mutations in Dusp23
AlleleSourceChrCoordTypePredicted EffectPPH Score
R4571:Dusp23 UTSW 1 172632614 critical splice donor site probably null
R6991:Dusp23 UTSW 1 172631657 missense probably benign 0.00
R7048:Dusp23 UTSW 1 172631686 nonsense probably null
Posted On2013-04-17