Incidental Mutation 'R3022:Bptf'
| ID |
265733 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Bptf
|
| Ensembl Gene |
ENSMUSG00000040481 |
| Gene Name |
bromodomain PHD finger transcription factor |
| Synonyms |
9430093H17Rik, Falz |
| MMRRC Submission |
040538-MU
|
| Accession Numbers |
Genbank: NM_176850; MGI: 2444008 |
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R3022 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
107033081-107132127 bp(-) (GRCm38) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
T to A
at 107111637 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102374
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057892]
[ENSMUST00000057892]
[ENSMUST00000057892]
[ENSMUST00000106762]
[ENSMUST00000106762]
[ENSMUST00000106762]
[ENSMUST00000106763]
[ENSMUST00000106763]
[ENSMUST00000106763]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000057892
|
| SMART Domains |
Protein: ENSMUSP00000052303
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.7e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
coiled coil region
|
864 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
961 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
987 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1062 |
1072 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1098 |
N/A |
INTRINSIC |
|
low complexity region
|
1225 |
1238 |
N/A |
INTRINSIC |
|
low complexity region
|
1251 |
1265 |
N/A |
INTRINSIC |
|
low complexity region
|
1491 |
1503 |
N/A |
INTRINSIC |
|
low complexity region
|
1594 |
1613 |
N/A |
INTRINSIC |
|
low complexity region
|
1636 |
1645 |
N/A |
INTRINSIC |
|
low complexity region
|
1665 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
1818 |
1834 |
N/A |
INTRINSIC |
|
coiled coil region
|
1908 |
1936 |
N/A |
INTRINSIC |
|
low complexity region
|
1941 |
1957 |
N/A |
INTRINSIC |
|
low complexity region
|
2051 |
2061 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2115 |
2128 |
N/A |
INTRINSIC |
|
low complexity region
|
2175 |
2197 |
N/A |
INTRINSIC |
|
low complexity region
|
2227 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2275 |
2312 |
N/A |
INTRINSIC |
|
low complexity region
|
2336 |
2355 |
N/A |
INTRINSIC |
|
low complexity region
|
2361 |
2378 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2430 |
2463 |
N/A |
INTRINSIC |
|
coiled coil region
|
2489 |
2527 |
N/A |
INTRINSIC |
|
coiled coil region
|
2576 |
2604 |
N/A |
INTRINSIC |
|
low complexity region
|
2663 |
2700 |
N/A |
INTRINSIC |
|
low complexity region
|
2713 |
2736 |
N/A |
INTRINSIC |
|
PHD
|
2744 |
2791 |
5.32e-9 |
SMART |
|
BROMO
|
2800 |
2908 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000057892
|
| SMART Domains |
Protein: ENSMUSP00000052303
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.7e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
coiled coil region
|
864 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
961 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
987 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1062 |
1072 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1098 |
N/A |
INTRINSIC |
|
low complexity region
|
1225 |
1238 |
N/A |
INTRINSIC |
|
low complexity region
|
1251 |
1265 |
N/A |
INTRINSIC |
|
low complexity region
|
1491 |
1503 |
N/A |
INTRINSIC |
|
low complexity region
|
1594 |
1613 |
N/A |
INTRINSIC |
|
low complexity region
|
1636 |
1645 |
N/A |
INTRINSIC |
|
low complexity region
|
1665 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
1818 |
1834 |
N/A |
INTRINSIC |
|
coiled coil region
|
1908 |
1936 |
N/A |
INTRINSIC |
|
low complexity region
|
1941 |
1957 |
N/A |
INTRINSIC |
|
low complexity region
|
2051 |
2061 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2115 |
2128 |
N/A |
INTRINSIC |
|
low complexity region
|
2175 |
2197 |
N/A |
INTRINSIC |
|
low complexity region
|
2227 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2275 |
2312 |
N/A |
INTRINSIC |
|
low complexity region
|
2336 |
2355 |
N/A |
INTRINSIC |
|
low complexity region
|
2361 |
2378 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2430 |
2463 |
N/A |
INTRINSIC |
|
coiled coil region
|
2489 |
2527 |
N/A |
INTRINSIC |
|
coiled coil region
|
2576 |
2604 |
N/A |
INTRINSIC |
|
low complexity region
|
2663 |
2700 |
N/A |
INTRINSIC |
|
low complexity region
|
2713 |
2736 |
N/A |
INTRINSIC |
|
PHD
|
2744 |
2791 |
5.32e-9 |
SMART |
|
BROMO
|
2800 |
2908 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000057892
|
| SMART Domains |
Protein: ENSMUSP00000052303
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.7e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
coiled coil region
|
864 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
961 |
973 |
N/A |
INTRINSIC |
|
low complexity region
|
987 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1062 |
1072 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1098 |
N/A |
INTRINSIC |
|
low complexity region
|
1225 |
1238 |
N/A |
INTRINSIC |
|
low complexity region
|
1251 |
1265 |
N/A |
INTRINSIC |
|
low complexity region
|
1491 |
1503 |
N/A |
INTRINSIC |
|
low complexity region
|
1594 |
1613 |
N/A |
INTRINSIC |
|
low complexity region
|
1636 |
1645 |
N/A |
INTRINSIC |
|
low complexity region
|
1665 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
1818 |
1834 |
N/A |
INTRINSIC |
|
coiled coil region
|
1908 |
1936 |
N/A |
INTRINSIC |
|
low complexity region
|
1941 |
1957 |
N/A |
INTRINSIC |
|
low complexity region
|
2051 |
2061 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2115 |
2128 |
N/A |
INTRINSIC |
|
low complexity region
|
2175 |
2197 |
N/A |
INTRINSIC |
|
low complexity region
|
2227 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2275 |
2312 |
N/A |
INTRINSIC |
|
low complexity region
|
2336 |
2355 |
N/A |
INTRINSIC |
|
low complexity region
|
2361 |
2378 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2430 |
2463 |
N/A |
INTRINSIC |
|
coiled coil region
|
2489 |
2527 |
N/A |
INTRINSIC |
|
coiled coil region
|
2576 |
2604 |
N/A |
INTRINSIC |
|
low complexity region
|
2663 |
2700 |
N/A |
INTRINSIC |
|
low complexity region
|
2713 |
2736 |
N/A |
INTRINSIC |
|
PHD
|
2744 |
2791 |
5.32e-9 |
SMART |
|
BROMO
|
2800 |
2908 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106762
|
| SMART Domains |
Protein: ENSMUSP00000102373
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.7e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
internal_repeat_1
|
589 |
642 |
6.48e-5 |
PROSPERO |
|
low complexity region
|
644 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
662 |
679 |
N/A |
INTRINSIC |
|
coiled coil region
|
926 |
956 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1039 |
1050 |
N/A |
INTRINSIC |
|
low complexity region
|
1114 |
1124 |
N/A |
INTRINSIC |
|
low complexity region
|
1138 |
1150 |
N/A |
INTRINSIC |
|
low complexity region
|
1277 |
1290 |
N/A |
INTRINSIC |
|
low complexity region
|
1303 |
1317 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1387 |
1440 |
6.48e-5 |
PROSPERO |
|
low complexity region
|
1543 |
1555 |
N/A |
INTRINSIC |
|
low complexity region
|
1646 |
1665 |
N/A |
INTRINSIC |
|
low complexity region
|
1688 |
1697 |
N/A |
INTRINSIC |
|
low complexity region
|
1717 |
1735 |
N/A |
INTRINSIC |
|
low complexity region
|
1870 |
1886 |
N/A |
INTRINSIC |
|
coiled coil region
|
1960 |
1988 |
N/A |
INTRINSIC |
|
low complexity region
|
1993 |
2009 |
N/A |
INTRINSIC |
|
low complexity region
|
2103 |
2113 |
N/A |
INTRINSIC |
|
low complexity region
|
2144 |
2159 |
N/A |
INTRINSIC |
|
low complexity region
|
2167 |
2180 |
N/A |
INTRINSIC |
|
low complexity region
|
2227 |
2249 |
N/A |
INTRINSIC |
|
low complexity region
|
2279 |
2304 |
N/A |
INTRINSIC |
|
low complexity region
|
2327 |
2364 |
N/A |
INTRINSIC |
|
low complexity region
|
2388 |
2407 |
N/A |
INTRINSIC |
|
low complexity region
|
2413 |
2430 |
N/A |
INTRINSIC |
|
low complexity region
|
2442 |
2472 |
N/A |
INTRINSIC |
|
low complexity region
|
2482 |
2515 |
N/A |
INTRINSIC |
|
coiled coil region
|
2541 |
2579 |
N/A |
INTRINSIC |
|
coiled coil region
|
2628 |
2656 |
N/A |
INTRINSIC |
|
low complexity region
|
2715 |
2752 |
N/A |
INTRINSIC |
|
low complexity region
|
2765 |
2788 |
N/A |
INTRINSIC |
|
PHD
|
2796 |
2843 |
5.32e-9 |
SMART |
|
BROMO
|
2852 |
2960 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106762
|
| SMART Domains |
Protein: ENSMUSP00000102373
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.7e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
internal_repeat_1
|
589 |
642 |
6.48e-5 |
PROSPERO |
|
low complexity region
|
644 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
662 |
679 |
N/A |
INTRINSIC |
|
coiled coil region
|
926 |
956 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1039 |
1050 |
N/A |
INTRINSIC |
|
low complexity region
|
1114 |
1124 |
N/A |
INTRINSIC |
|
low complexity region
|
1138 |
1150 |
N/A |
INTRINSIC |
|
low complexity region
|
1277 |
1290 |
N/A |
INTRINSIC |
|
low complexity region
|
1303 |
1317 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1387 |
1440 |
6.48e-5 |
PROSPERO |
|
low complexity region
|
1543 |
1555 |
N/A |
INTRINSIC |
|
low complexity region
|
1646 |
1665 |
N/A |
INTRINSIC |
|
low complexity region
|
1688 |
1697 |
N/A |
INTRINSIC |
|
low complexity region
|
1717 |
1735 |
N/A |
INTRINSIC |
|
low complexity region
|
1870 |
1886 |
N/A |
INTRINSIC |
|
coiled coil region
|
1960 |
1988 |
N/A |
INTRINSIC |
|
low complexity region
|
1993 |
2009 |
N/A |
INTRINSIC |
|
low complexity region
|
2103 |
2113 |
N/A |
INTRINSIC |
|
low complexity region
|
2144 |
2159 |
N/A |
INTRINSIC |
|
low complexity region
|
2167 |
2180 |
N/A |
INTRINSIC |
|
low complexity region
|
2227 |
2249 |
N/A |
INTRINSIC |
|
low complexity region
|
2279 |
2304 |
N/A |
INTRINSIC |
|
low complexity region
|
2327 |
2364 |
N/A |
INTRINSIC |
|
low complexity region
|
2388 |
2407 |
N/A |
INTRINSIC |
|
low complexity region
|
2413 |
2430 |
N/A |
INTRINSIC |
|
low complexity region
|
2442 |
2472 |
N/A |
INTRINSIC |
|
low complexity region
|
2482 |
2515 |
N/A |
INTRINSIC |
|
coiled coil region
|
2541 |
2579 |
N/A |
INTRINSIC |
|
coiled coil region
|
2628 |
2656 |
N/A |
INTRINSIC |
|
low complexity region
|
2715 |
2752 |
N/A |
INTRINSIC |
|
low complexity region
|
2765 |
2788 |
N/A |
INTRINSIC |
|
PHD
|
2796 |
2843 |
5.32e-9 |
SMART |
|
BROMO
|
2852 |
2960 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106762
|
| SMART Domains |
Protein: ENSMUSP00000102373
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.7e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
internal_repeat_1
|
589 |
642 |
6.48e-5 |
PROSPERO |
|
low complexity region
|
644 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
662 |
679 |
N/A |
INTRINSIC |
|
coiled coil region
|
926 |
956 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1039 |
1050 |
N/A |
INTRINSIC |
|
low complexity region
|
1114 |
1124 |
N/A |
INTRINSIC |
|
low complexity region
|
1138 |
1150 |
N/A |
INTRINSIC |
|
low complexity region
|
1277 |
1290 |
N/A |
INTRINSIC |
|
low complexity region
|
1303 |
1317 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1387 |
1440 |
6.48e-5 |
PROSPERO |
|
low complexity region
|
1543 |
1555 |
N/A |
INTRINSIC |
|
low complexity region
|
1646 |
1665 |
N/A |
INTRINSIC |
|
low complexity region
|
1688 |
1697 |
N/A |
INTRINSIC |
|
low complexity region
|
1717 |
1735 |
N/A |
INTRINSIC |
|
low complexity region
|
1870 |
1886 |
N/A |
INTRINSIC |
|
coiled coil region
|
1960 |
1988 |
N/A |
INTRINSIC |
|
low complexity region
|
1993 |
2009 |
N/A |
INTRINSIC |
|
low complexity region
|
2103 |
2113 |
N/A |
INTRINSIC |
|
low complexity region
|
2144 |
2159 |
N/A |
INTRINSIC |
|
low complexity region
|
2167 |
2180 |
N/A |
INTRINSIC |
|
low complexity region
|
2227 |
2249 |
N/A |
INTRINSIC |
|
low complexity region
|
2279 |
2304 |
N/A |
INTRINSIC |
|
low complexity region
|
2327 |
2364 |
N/A |
INTRINSIC |
|
low complexity region
|
2388 |
2407 |
N/A |
INTRINSIC |
|
low complexity region
|
2413 |
2430 |
N/A |
INTRINSIC |
|
low complexity region
|
2442 |
2472 |
N/A |
INTRINSIC |
|
low complexity region
|
2482 |
2515 |
N/A |
INTRINSIC |
|
coiled coil region
|
2541 |
2579 |
N/A |
INTRINSIC |
|
coiled coil region
|
2628 |
2656 |
N/A |
INTRINSIC |
|
low complexity region
|
2715 |
2752 |
N/A |
INTRINSIC |
|
low complexity region
|
2765 |
2788 |
N/A |
INTRINSIC |
|
PHD
|
2796 |
2843 |
5.32e-9 |
SMART |
|
BROMO
|
2852 |
2960 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106763
|
| SMART Domains |
Protein: ENSMUSP00000102374
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.9e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
low complexity region
|
624 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
707 |
717 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
742 |
N/A |
INTRINSIC |
|
coiled coil region
|
989 |
1019 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1088 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1177 |
1187 |
N/A |
INTRINSIC |
|
low complexity region
|
1201 |
1213 |
N/A |
INTRINSIC |
|
low complexity region
|
1340 |
1353 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1380 |
N/A |
INTRINSIC |
|
low complexity region
|
1606 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1709 |
1728 |
N/A |
INTRINSIC |
|
low complexity region
|
1751 |
1760 |
N/A |
INTRINSIC |
|
low complexity region
|
1780 |
1798 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1949 |
N/A |
INTRINSIC |
|
coiled coil region
|
2023 |
2051 |
N/A |
INTRINSIC |
|
low complexity region
|
2056 |
2072 |
N/A |
INTRINSIC |
|
low complexity region
|
2166 |
2176 |
N/A |
INTRINSIC |
|
low complexity region
|
2207 |
2222 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2243 |
N/A |
INTRINSIC |
|
low complexity region
|
2290 |
2312 |
N/A |
INTRINSIC |
|
low complexity region
|
2342 |
2367 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2427 |
N/A |
INTRINSIC |
|
low complexity region
|
2451 |
2470 |
N/A |
INTRINSIC |
|
low complexity region
|
2476 |
2493 |
N/A |
INTRINSIC |
|
low complexity region
|
2505 |
2535 |
N/A |
INTRINSIC |
|
low complexity region
|
2545 |
2578 |
N/A |
INTRINSIC |
|
coiled coil region
|
2604 |
2642 |
N/A |
INTRINSIC |
|
coiled coil region
|
2691 |
2719 |
N/A |
INTRINSIC |
|
low complexity region
|
2778 |
2815 |
N/A |
INTRINSIC |
|
low complexity region
|
2828 |
2851 |
N/A |
INTRINSIC |
|
PHD
|
2859 |
2906 |
5.32e-9 |
SMART |
|
BROMO
|
2915 |
3023 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106763
|
| SMART Domains |
Protein: ENSMUSP00000102374
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.9e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
low complexity region
|
624 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
707 |
717 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
742 |
N/A |
INTRINSIC |
|
coiled coil region
|
989 |
1019 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1088 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1177 |
1187 |
N/A |
INTRINSIC |
|
low complexity region
|
1201 |
1213 |
N/A |
INTRINSIC |
|
low complexity region
|
1340 |
1353 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1380 |
N/A |
INTRINSIC |
|
low complexity region
|
1606 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1709 |
1728 |
N/A |
INTRINSIC |
|
low complexity region
|
1751 |
1760 |
N/A |
INTRINSIC |
|
low complexity region
|
1780 |
1798 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1949 |
N/A |
INTRINSIC |
|
coiled coil region
|
2023 |
2051 |
N/A |
INTRINSIC |
|
low complexity region
|
2056 |
2072 |
N/A |
INTRINSIC |
|
low complexity region
|
2166 |
2176 |
N/A |
INTRINSIC |
|
low complexity region
|
2207 |
2222 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2243 |
N/A |
INTRINSIC |
|
low complexity region
|
2290 |
2312 |
N/A |
INTRINSIC |
|
low complexity region
|
2342 |
2367 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2427 |
N/A |
INTRINSIC |
|
low complexity region
|
2451 |
2470 |
N/A |
INTRINSIC |
|
low complexity region
|
2476 |
2493 |
N/A |
INTRINSIC |
|
low complexity region
|
2505 |
2535 |
N/A |
INTRINSIC |
|
low complexity region
|
2545 |
2578 |
N/A |
INTRINSIC |
|
coiled coil region
|
2604 |
2642 |
N/A |
INTRINSIC |
|
coiled coil region
|
2691 |
2719 |
N/A |
INTRINSIC |
|
low complexity region
|
2778 |
2815 |
N/A |
INTRINSIC |
|
low complexity region
|
2828 |
2851 |
N/A |
INTRINSIC |
|
PHD
|
2859 |
2906 |
5.32e-9 |
SMART |
|
BROMO
|
2915 |
3023 |
5.5e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106763
|
| SMART Domains |
Protein: ENSMUSP00000102374
Gene: ENSMUSG00000040481
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
49 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
77 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
137 |
197 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
215 |
N/A |
INTRINSIC |
|
DDT
|
252 |
312 |
2.02e-23 |
SMART |
|
Pfam:WHIM1
|
351 |
400 |
4.9e-8 |
PFAM |
|
PHD
|
404 |
447 |
2.23e-11 |
SMART |
|
low complexity region
|
624 |
639 |
N/A |
INTRINSIC |
|
low complexity region
|
707 |
717 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
742 |
N/A |
INTRINSIC |
|
coiled coil region
|
989 |
1019 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1088 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1177 |
1187 |
N/A |
INTRINSIC |
|
low complexity region
|
1201 |
1213 |
N/A |
INTRINSIC |
|
low complexity region
|
1340 |
1353 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1380 |
N/A |
INTRINSIC |
|
low complexity region
|
1606 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1709 |
1728 |
N/A |
INTRINSIC |
|
low complexity region
|
1751 |
1760 |
N/A |
INTRINSIC |
|
low complexity region
|
1780 |
1798 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1949 |
N/A |
INTRINSIC |
|
coiled coil region
|
2023 |
2051 |
N/A |
INTRINSIC |
|
low complexity region
|
2056 |
2072 |
N/A |
INTRINSIC |
|
low complexity region
|
2166 |
2176 |
N/A |
INTRINSIC |
|
low complexity region
|
2207 |
2222 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2243 |
N/A |
INTRINSIC |
|
low complexity region
|
2290 |
2312 |
N/A |
INTRINSIC |
|
low complexity region
|
2342 |
2367 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2427 |
N/A |
INTRINSIC |
|
low complexity region
|
2451 |
2470 |
N/A |
INTRINSIC |
|
low complexity region
|
2476 |
2493 |
N/A |
INTRINSIC |
|
low complexity region
|
2505 |
2535 |
N/A |
INTRINSIC |
|
low complexity region
|
2545 |
2578 |
N/A |
INTRINSIC |
|
coiled coil region
|
2604 |
2642 |
N/A |
INTRINSIC |
|
coiled coil region
|
2691 |
2719 |
N/A |
INTRINSIC |
|
low complexity region
|
2778 |
2815 |
N/A |
INTRINSIC |
|
low complexity region
|
2828 |
2851 |
N/A |
INTRINSIC |
|
PHD
|
2859 |
2906 |
5.32e-9 |
SMART |
|
BROMO
|
2915 |
3023 |
5.5e-37 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription. Two alternative transcripts encoding different isoforms have been described completely. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality during organogenesis with embryonic growth arrest around early gastrulation and a greatly reduced ectoplacental cone. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(58) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(56) |
| Other mutations in this stock |
Total: 11 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Dnah3 |
T |
A |
7: 120,078,481 |
I406F |
possibly damaging |
Het |
| Dnah7b |
G |
A |
1: 46,182,423 |
C1229Y |
probably damaging |
Het |
| Flywch1 |
T |
C |
17: 23,763,108 |
R41G |
probably benign |
Het |
| Itpkb |
A |
T |
1: 180,418,323 |
T802S |
probably damaging |
Het |
| Kdm1b |
C |
T |
13: 47,063,077 |
R308W |
probably damaging |
Het |
| Olfr433 |
A |
G |
1: 174,042,084 |
I45V |
probably benign |
Het |
| Padi2 |
T |
A |
4: 140,937,988 |
V468E |
possibly damaging |
Het |
| Prom1 |
G |
A |
5: 44,047,574 |
T177I |
probably damaging |
Het |
| Rufy4 |
T |
C |
1: 74,147,663 |
C537R |
probably damaging |
Het |
| Stx5a |
T |
C |
19: 8,755,154 |
|
probably benign |
Het |
| Vmn1r237 |
T |
A |
17: 21,314,447 |
I144K |
probably damaging |
Het |
|
| Other mutations in Bptf |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00553:Bptf
|
APN |
11 |
107055279 |
missense |
possibly damaging |
0.88 |
|
IGL00664:Bptf
|
APN |
11 |
107077665 |
missense |
possibly damaging |
0.78 |
|
IGL00705:Bptf
|
APN |
11 |
107095708 |
splice site |
probably benign |
|
|
IGL00796:Bptf
|
APN |
11 |
107054550 |
missense |
probably damaging |
1.00 |
|
IGL00834:Bptf
|
APN |
11 |
107073928 |
missense |
possibly damaging |
0.59 |
|
IGL01155:Bptf
|
APN |
11 |
107080727 |
missense |
probably damaging |
1.00 |
|
IGL01314:Bptf
|
APN |
11 |
107054853 |
missense |
probably damaging |
1.00 |
|
IGL01371:Bptf
|
APN |
11 |
107055907 |
missense |
probably benign |
0.00 |
|
IGL01567:Bptf
|
APN |
11 |
107058774 |
missense |
probably damaging |
1.00 |
|
IGL01794:Bptf
|
APN |
11 |
107053221 |
critical splice donor site |
probably null |
|
|
IGL02108:Bptf
|
APN |
11 |
107074988 |
missense |
probably benign |
0.45 |
|
IGL02367:Bptf
|
APN |
11 |
107073352 |
missense |
probably benign |
|
|
IGL02437:Bptf
|
APN |
11 |
107074695 |
missense |
probably benign |
0.00 |
|
IGL02589:Bptf
|
APN |
11 |
107111531 |
missense |
possibly damaging |
0.92 |
|
IGL02897:Bptf
|
APN |
11 |
107047121 |
missense |
probably damaging |
1.00 |
|
IGL02935:Bptf
|
APN |
11 |
107080799 |
missense |
probably damaging |
1.00 |
|
IGL02954:Bptf
|
APN |
11 |
107054749 |
missense |
possibly damaging |
0.89 |
|
IGL02982:Bptf
|
APN |
11 |
107076674 |
missense |
probably damaging |
1.00 |
|
IGL03109:Bptf
|
APN |
11 |
107061701 |
missense |
possibly damaging |
0.53 |
|
IGL03265:Bptf
|
APN |
11 |
107054628 |
missense |
probably benign |
0.00 |
|
IGL03403:Bptf
|
APN |
11 |
107099733 |
missense |
possibly damaging |
0.51 |
|
Anodyne
|
UTSW |
11 |
107043631 |
critical splice donor site |
probably null |
|
|
Arroyo
|
UTSW |
11 |
107042690 |
missense |
probably benign |
0.32 |
|
mojado
|
UTSW |
11 |
107044640 |
missense |
probably benign |
0.03 |
|
IGL03097:Bptf
|
UTSW |
11 |
107077680 |
missense |
probably damaging |
1.00 |
|
PIT4486001:Bptf
|
UTSW |
11 |
107054788 |
missense |
probably damaging |
0.98 |
|
R0066:Bptf
|
UTSW |
11 |
107062136 |
missense |
possibly damaging |
0.90 |
|
R0157:Bptf
|
UTSW |
11 |
107074658 |
missense |
possibly damaging |
0.89 |
|
R0320:Bptf
|
UTSW |
11 |
107072819 |
missense |
probably damaging |
1.00 |
|
R0328:Bptf
|
UTSW |
11 |
107047127 |
missense |
probably damaging |
1.00 |
|
R0402:Bptf
|
UTSW |
11 |
107074114 |
missense |
probably damaging |
1.00 |
|
R0482:Bptf
|
UTSW |
11 |
107081262 |
missense |
probably benign |
0.13 |
|
R0574:Bptf
|
UTSW |
11 |
107076527 |
missense |
probably damaging |
1.00 |
|
R0598:Bptf
|
UTSW |
11 |
107072965 |
missense |
probably damaging |
0.99 |
|
R0599:Bptf
|
UTSW |
11 |
107068382 |
missense |
probably damaging |
1.00 |
|
R0601:Bptf
|
UTSW |
11 |
107061692 |
missense |
probably benign |
0.04 |
|
R0744:Bptf
|
UTSW |
11 |
107110812 |
critical splice donor site |
probably null |
|
|
R0836:Bptf
|
UTSW |
11 |
107110812 |
critical splice donor site |
probably null |
|
|
R0885:Bptf
|
UTSW |
11 |
107043791 |
missense |
probably damaging |
1.00 |
|
R1070:Bptf
|
UTSW |
11 |
107055055 |
missense |
possibly damaging |
0.92 |
|
R1252:Bptf
|
UTSW |
11 |
107073251 |
missense |
probably benign |
0.00 |
|
R1370:Bptf
|
UTSW |
11 |
107047094 |
missense |
probably damaging |
0.99 |
|
R1428:Bptf
|
UTSW |
11 |
107073047 |
missense |
probably damaging |
0.99 |
|
R1467:Bptf
|
UTSW |
11 |
107055055 |
missense |
possibly damaging |
0.92 |
|
R1467:Bptf
|
UTSW |
11 |
107055055 |
missense |
possibly damaging |
0.92 |
|
R1742:Bptf
|
UTSW |
11 |
107110951 |
missense |
probably damaging |
1.00 |
|
R1816:Bptf
|
UTSW |
11 |
107060579 |
missense |
probably damaging |
1.00 |
|
R1858:Bptf
|
UTSW |
11 |
107073301 |
missense |
probably benign |
0.00 |
|
R1989:Bptf
|
UTSW |
11 |
107074826 |
missense |
probably damaging |
1.00 |
|
R2253:Bptf
|
UTSW |
11 |
107111322 |
missense |
probably damaging |
1.00 |
|
R2392:Bptf
|
UTSW |
11 |
107072747 |
missense |
probably damaging |
1.00 |
|
R2431:Bptf
|
UTSW |
11 |
107047240 |
missense |
possibly damaging |
0.48 |
|
R3161:Bptf
|
UTSW |
11 |
107074476 |
missense |
probably damaging |
1.00 |
|
R3686:Bptf
|
UTSW |
11 |
107074198 |
missense |
probably benign |
0.25 |
|
R3687:Bptf
|
UTSW |
11 |
107074198 |
missense |
probably benign |
0.25 |
|
R3688:Bptf
|
UTSW |
11 |
107074198 |
missense |
probably benign |
0.25 |
|
R3787:Bptf
|
UTSW |
11 |
107073827 |
missense |
probably damaging |
1.00 |
|
R3834:Bptf
|
UTSW |
11 |
107073857 |
missense |
probably benign |
0.05 |
|
R3885:Bptf
|
UTSW |
11 |
107074513 |
missense |
probably damaging |
0.97 |
|
R4090:Bptf
|
UTSW |
11 |
107081523 |
missense |
probably damaging |
0.99 |
|
R4398:Bptf
|
UTSW |
11 |
107110844 |
missense |
probably damaging |
1.00 |
|
R4437:Bptf
|
UTSW |
11 |
107074474 |
missense |
possibly damaging |
0.59 |
|
R4514:Bptf
|
UTSW |
11 |
107077692 |
missense |
probably damaging |
1.00 |
|
R4565:Bptf
|
UTSW |
11 |
107073010 |
missense |
probably damaging |
1.00 |
|
R4715:Bptf
|
UTSW |
11 |
107047181 |
missense |
probably damaging |
1.00 |
|
R4748:Bptf
|
UTSW |
11 |
107095880 |
missense |
probably damaging |
0.96 |
|
R4764:Bptf
|
UTSW |
11 |
107043694 |
missense |
probably damaging |
1.00 |
|
R4885:Bptf
|
UTSW |
11 |
107074648 |
missense |
probably benign |
0.39 |
|
R4901:Bptf
|
UTSW |
11 |
107110860 |
nonsense |
probably null |
|
|
R4995:Bptf
|
UTSW |
11 |
107054565 |
missense |
probably damaging |
0.98 |
|
R5057:Bptf
|
UTSW |
11 |
107082528 |
missense |
probably damaging |
0.98 |
|
R5120:Bptf
|
UTSW |
11 |
107073385 |
missense |
probably damaging |
0.99 |
|
R5320:Bptf
|
UTSW |
11 |
107081367 |
nonsense |
probably null |
|
|
R5329:Bptf
|
UTSW |
11 |
107073295 |
missense |
probably benign |
0.06 |
|
R5418:Bptf
|
UTSW |
11 |
107111294 |
missense |
probably damaging |
1.00 |
|
R5461:Bptf
|
UTSW |
11 |
107061764 |
missense |
probably damaging |
1.00 |
|
R5664:Bptf
|
UTSW |
11 |
107073699 |
missense |
probably benign |
0.01 |
|
R5718:Bptf
|
UTSW |
11 |
107111434 |
missense |
probably damaging |
1.00 |
|
R5774:Bptf
|
UTSW |
11 |
107111137 |
missense |
probably damaging |
1.00 |
|
R5851:Bptf
|
UTSW |
11 |
107110862 |
missense |
probably damaging |
1.00 |
|
R5930:Bptf
|
UTSW |
11 |
107073196 |
missense |
probably damaging |
1.00 |
|
R5949:Bptf
|
UTSW |
11 |
107111089 |
missense |
probably damaging |
0.99 |
|
R5975:Bptf
|
UTSW |
11 |
107035864 |
utr 3 prime |
probably benign |
|
|
R6027:Bptf
|
UTSW |
11 |
107074945 |
missense |
probably damaging |
1.00 |
|
R6128:Bptf
|
UTSW |
11 |
107074690 |
missense |
possibly damaging |
0.87 |
|
R6337:Bptf
|
UTSW |
11 |
107058779 |
missense |
possibly damaging |
0.89 |
|
R6407:Bptf
|
UTSW |
11 |
107111126 |
missense |
probably damaging |
1.00 |
|
R6470:Bptf
|
UTSW |
11 |
107072767 |
missense |
probably damaging |
1.00 |
|
R6487:Bptf
|
UTSW |
11 |
107077726 |
missense |
probably damaging |
0.99 |
|
R6501:Bptf
|
UTSW |
11 |
107077683 |
missense |
probably null |
1.00 |
|
R6755:Bptf
|
UTSW |
11 |
107047256 |
missense |
probably benign |
0.27 |
|
R6861:Bptf
|
UTSW |
11 |
107062565 |
missense |
probably damaging |
1.00 |
|
R6866:Bptf
|
UTSW |
11 |
107073580 |
missense |
probably damaging |
1.00 |
|
R6879:Bptf
|
UTSW |
11 |
107042690 |
missense |
probably benign |
0.32 |
|
R6927:Bptf
|
UTSW |
11 |
107054595 |
missense |
probably damaging |
1.00 |
|
R6944:Bptf
|
UTSW |
11 |
107080823 |
missense |
probably damaging |
1.00 |
|
R7082:Bptf
|
UTSW |
11 |
107086747 |
missense |
probably benign |
0.00 |
|
R7136:Bptf
|
UTSW |
11 |
107099715 |
missense |
probably damaging |
1.00 |
|
R7162:Bptf
|
UTSW |
11 |
107043631 |
critical splice donor site |
probably null |
|
|
R7171:Bptf
|
UTSW |
11 |
107131407 |
missense |
unknown |
|
|
R7193:Bptf
|
UTSW |
11 |
107054809 |
nonsense |
probably null |
|
|
R7210:Bptf
|
UTSW |
11 |
107054464 |
nonsense |
probably null |
|
|
R7221:Bptf
|
UTSW |
11 |
107054832 |
missense |
probably damaging |
1.00 |
|
R7316:Bptf
|
UTSW |
11 |
107073109 |
missense |
probably damaging |
1.00 |
|
R7316:Bptf
|
UTSW |
11 |
107110914 |
nonsense |
probably null |
|
|
R7422:Bptf
|
UTSW |
11 |
107060558 |
missense |
probably damaging |
1.00 |
|
R7454:Bptf
|
UTSW |
11 |
107044640 |
missense |
probably benign |
0.03 |
|
R7657:Bptf
|
UTSW |
11 |
107074729 |
missense |
probably damaging |
1.00 |
|
R7718:Bptf
|
UTSW |
11 |
107081456 |
missense |
possibly damaging |
0.65 |
|
R7827:Bptf
|
UTSW |
11 |
107047187 |
missense |
probably benign |
0.01 |
|
R7844:Bptf
|
UTSW |
11 |
107074061 |
missense |
probably damaging |
0.97 |
|
R7992:Bptf
|
UTSW |
11 |
107110883 |
missense |
probably benign |
0.00 |
|
R8001:Bptf
|
UTSW |
11 |
107047340 |
nonsense |
probably null |
|
|
R8037:Bptf
|
UTSW |
11 |
107055950 |
missense |
probably damaging |
1.00 |
|
R8122:Bptf
|
UTSW |
11 |
107036591 |
critical splice acceptor site |
probably null |
|
|
R8235:Bptf
|
UTSW |
11 |
107076632 |
missense |
probably benign |
0.04 |
|
R8308:Bptf
|
UTSW |
11 |
107052989 |
missense |
probably damaging |
0.99 |
|
R8409:Bptf
|
UTSW |
11 |
107062669 |
missense |
probably damaging |
1.00 |
|
R8464:Bptf
|
UTSW |
11 |
107131342 |
missense |
probably benign |
0.01 |
|
R8477:Bptf
|
UTSW |
11 |
107052853 |
missense |
probably damaging |
0.98 |
|
R8482:Bptf
|
UTSW |
11 |
107043698 |
missense |
probably benign |
0.19 |
|
R8515:Bptf
|
UTSW |
11 |
107055238 |
missense |
possibly damaging |
0.85 |
|
R8519:Bptf
|
UTSW |
11 |
107061764 |
missense |
probably damaging |
1.00 |
|
R8708:Bptf
|
UTSW |
11 |
107073313 |
missense |
probably damaging |
0.99 |
|
R8708:Bptf
|
UTSW |
11 |
107073314 |
missense |
probably damaging |
1.00 |
|
R8722:Bptf
|
UTSW |
11 |
107131469 |
missense |
unknown |
|
|
R8732:Bptf
|
UTSW |
11 |
107040380 |
missense |
probably damaging |
1.00 |
|
R8783:Bptf
|
UTSW |
11 |
107131531 |
missense |
unknown |
|
|
R8828:Bptf
|
UTSW |
11 |
107055010 |
missense |
probably damaging |
0.98 |
|
R9004:Bptf
|
UTSW |
11 |
107054887 |
missense |
probably damaging |
1.00 |
|
R9010:Bptf
|
UTSW |
11 |
107073750 |
missense |
probably damaging |
1.00 |
|
R9035:Bptf
|
UTSW |
11 |
107073016 |
missense |
probably damaging |
1.00 |
|
R9083:Bptf
|
UTSW |
11 |
107068350 |
missense |
probably damaging |
1.00 |
|
R9211:Bptf
|
UTSW |
11 |
107055298 |
missense |
probably damaging |
1.00 |
|
R9345:Bptf
|
UTSW |
11 |
107080762 |
missense |
possibly damaging |
0.77 |
|
R9393:Bptf
|
UTSW |
11 |
107074308 |
missense |
probably benign |
0.00 |
|
R9451:Bptf
|
UTSW |
11 |
107044585 |
missense |
probably damaging |
1.00 |
|
R9561:Bptf
|
UTSW |
11 |
107074128 |
nonsense |
probably null |
|
|
R9632:Bptf
|
UTSW |
11 |
107061719 |
missense |
probably damaging |
1.00 |
|
R9648:Bptf
|
UTSW |
11 |
107052894 |
missense |
probably damaging |
0.99 |
|
R9650:Bptf
|
UTSW |
11 |
107044586 |
missense |
probably benign |
0.15 |
|
R9658:Bptf
|
UTSW |
11 |
107111344 |
missense |
probably damaging |
1.00 |
|
R9775:Bptf
|
UTSW |
11 |
107043676 |
missense |
probably benign |
0.04 |
|
R9776:Bptf
|
UTSW |
11 |
107078570 |
missense |
probably damaging |
1.00 |
|
Z1088:Bptf
|
UTSW |
11 |
107074582 |
missense |
probably benign |
0.00 |
|
Z1176:Bptf
|
UTSW |
11 |
107058684 |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAAACGTTGCCAAAGTTCCG -3'
(R):5'- CTGAAGAACTAAGTCATTGAACAGC -3'
Sequencing Primer
(F):5'- GTTCCGCACCACCTCATAAATGG -3'
(R):5'- ATATCTCACTGTGTAGACCAGGCTG -3'
|
| Posted On |
2015-02-05 |
Incidental Mutation