Incidental Mutation 'R2870:St5'
| ID |
266516 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St5
|
| Ensembl Gene |
ENSMUSG00000031024 |
| Gene Name |
suppression of tumorigenicity 5 |
| Synonyms |
2610305K15Rik, 2010004M01Rik |
| MMRRC Submission |
040458-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.414)
|
| Stock # |
R2870 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
109523911-109703605 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 109557430 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 38
(Y38N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000078264
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000077909]
[ENSMUST00000079282]
[ENSMUST00000084738]
[ENSMUST00000168005]
[ENSMUST00000207394]
[ENSMUST00000207745]
[ENSMUST00000208583]
|
| AlphaFold |
Q924W7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000077909
AA Change: Y38N
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000077067
Gene: ENSMUSG00000031024
AA Change: Y38N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
28 |
46 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
213 |
N/A |
INTRINSIC |
|
low complexity region
|
314 |
326 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
407 |
426 |
N/A |
INTRINSIC |
|
low complexity region
|
577 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
624 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
645 |
656 |
N/A |
INTRINSIC |
|
uDENN
|
690 |
781 |
1.16e-30 |
SMART |
|
DENN
|
788 |
972 |
7.84e-78 |
SMART |
|
low complexity region
|
1007 |
1014 |
N/A |
INTRINSIC |
|
dDENN
|
1019 |
1086 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000079282
AA Change: Y38N
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000078264
Gene: ENSMUSG00000031024
AA Change: Y38N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
28 |
46 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
213 |
N/A |
INTRINSIC |
|
low complexity region
|
314 |
326 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
407 |
426 |
N/A |
INTRINSIC |
|
low complexity region
|
577 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
624 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
645 |
656 |
N/A |
INTRINSIC |
|
uDENN
|
690 |
781 |
1.16e-30 |
SMART |
|
DENN
|
788 |
972 |
7.84e-78 |
SMART |
|
low complexity region
|
1007 |
1014 |
N/A |
INTRINSIC |
|
dDENN
|
1019 |
1086 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000084738
|
| SMART Domains |
Protein: ENSMUSP00000081789
Gene: ENSMUSG00000031024
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
228 |
239 |
N/A |
INTRINSIC |
|
uDENN
|
273 |
364 |
1.16e-30 |
SMART |
|
DENN
|
371 |
555 |
7.84e-78 |
SMART |
|
low complexity region
|
590 |
597 |
N/A |
INTRINSIC |
|
dDENN
|
602 |
669 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168005
|
| SMART Domains |
Protein: ENSMUSP00000130119
Gene: ENSMUSG00000031024
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
228 |
239 |
N/A |
INTRINSIC |
|
uDENN
|
273 |
364 |
1.16e-30 |
SMART |
|
DENN
|
371 |
555 |
7.84e-78 |
SMART |
|
low complexity region
|
590 |
597 |
N/A |
INTRINSIC |
|
dDENN
|
602 |
669 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207394
AA Change: Y38N
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207745
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208557
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208583
AA Change: Y38N
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208981
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actrt3 |
A |
G |
3: 30,599,698 (GRCm38) |
V51A |
probably damaging |
Het |
| Adgb |
C |
T |
10: 10,431,281 (GRCm38) |
|
probably null |
Het |
| Als2 |
A |
G |
1: 59,211,137 (GRCm38) |
S483P |
probably damaging |
Het |
| Ankrd10 |
C |
T |
8: 11,615,682 (GRCm38) |
R306H |
probably damaging |
Het |
| Arhgef10 |
A |
G |
8: 14,975,666 (GRCm38) |
I459V |
probably benign |
Het |
| Arhgef10 |
T |
C |
8: 14,975,093 (GRCm38) |
|
probably null |
Het |
| Armc2 |
C |
T |
10: 41,966,700 (GRCm38) |
|
probably null |
Het |
| Atp12a |
A |
G |
14: 56,386,950 (GRCm38) |
R952G |
possibly damaging |
Het |
| Atp6v1g1 |
A |
G |
4: 63,550,021 (GRCm38) |
Y87C |
probably benign |
Het |
| C030034I22Rik |
T |
A |
17: 69,418,111 (GRCm38) |
|
noncoding transcript |
Het |
| Cacna2d1 |
G |
A |
5: 16,312,568 (GRCm38) |
C404Y |
probably damaging |
Het |
| Ccdc163 |
T |
C |
4: 116,741,861 (GRCm38) |
|
silent |
Het |
| Ccdc59 |
A |
T |
10: 105,841,527 (GRCm38) |
K9M |
possibly damaging |
Het |
| Cd6 |
A |
G |
19: 10,794,626 (GRCm38) |
I307T |
possibly damaging |
Het |
| Cimap1d |
G |
A |
10: 79,645,653 (GRCm38) |
T14I |
probably benign |
Het |
| Clasrp |
C |
A |
7: 19,585,240 (GRCm38) |
|
probably benign |
Het |
| Csmd2 |
T |
C |
4: 128,557,718 (GRCm38) |
F113S |
unknown |
Het |
| Csmd3 |
C |
T |
15: 47,857,924 (GRCm38) |
G1437D |
probably damaging |
Het |
| Cyp4a14 |
C |
A |
4: 115,487,301 (GRCm38) |
G456W |
probably damaging |
Het |
| Cyp4a30b |
A |
G |
4: 115,458,362 (GRCm38) |
H260R |
possibly damaging |
Het |
| Dcp1b |
C |
T |
6: 119,214,774 (GRCm38) |
S217L |
probably benign |
Het |
| Dhx57 |
A |
T |
17: 80,251,376 (GRCm38) |
D1051E |
probably benign |
Het |
| Dmp1 |
A |
G |
5: 104,212,108 (GRCm38) |
S217G |
probably benign |
Het |
| Eif4enif1 |
C |
T |
11: 3,242,586 (GRCm38) |
P805S |
probably damaging |
Het |
| Eral1 |
A |
G |
11: 78,076,278 (GRCm38) |
I164T |
possibly damaging |
Het |
| Esr1 |
G |
A |
10: 4,997,890 (GRCm38) |
R481H |
probably damaging |
Het |
| Fan1 |
A |
G |
7: 64,363,190 (GRCm38) |
I668T |
probably benign |
Het |
| Gbp11 |
C |
T |
5: 105,331,000 (GRCm38) |
D191N |
probably benign |
Het |
| Gm21759 |
T |
A |
5: 8,180,863 (GRCm38) |
|
probably benign |
Het |
| Gm5454 |
C |
A |
13: 103,357,523 (GRCm38) |
|
noncoding transcript |
Het |
| Gm9874 |
A |
T |
17: 30,485,789 (GRCm38) |
|
probably benign |
Het |
| Gria2 |
G |
A |
3: 80,702,492 (GRCm38) |
T670I |
probably damaging |
Het |
| Gria4 |
T |
A |
9: 4,503,614 (GRCm38) |
N334I |
probably damaging |
Het |
| Grm5 |
T |
C |
7: 87,602,722 (GRCm38) |
V60A |
possibly damaging |
Het |
| Ift172 |
C |
T |
5: 31,257,861 (GRCm38) |
V1335I |
probably benign |
Het |
| Ino80d |
C |
T |
1: 63,061,039 (GRCm38) |
|
probably null |
Het |
| Kif1c |
A |
G |
11: 70,724,081 (GRCm38) |
E567G |
probably damaging |
Het |
| Krt31 |
T |
G |
11: 100,047,873 (GRCm38) |
N298T |
possibly damaging |
Het |
| Mapk7 |
C |
A |
11: 61,490,212 (GRCm38) |
|
probably benign |
Het |
| Marchf8 |
C |
T |
6: 116,401,145 (GRCm38) |
|
probably benign |
Het |
| Matr3 |
T |
A |
18: 35,572,296 (GRCm38) |
S91R |
probably benign |
Het |
| Mdm1 |
A |
G |
10: 118,150,942 (GRCm38) |
T267A |
probably benign |
Het |
| Mlxip |
A |
G |
5: 123,452,667 (GRCm38) |
M878V |
probably benign |
Het |
| Mtm1 |
T |
C |
X: 71,296,362 (GRCm38) |
|
probably benign |
Homo |
| Mtor |
T |
A |
4: 148,540,030 (GRCm38) |
M2089K |
probably benign |
Het |
| Mylk2 |
A |
G |
2: 152,919,348 (GRCm38) |
K457R |
probably damaging |
Het |
| Nell1 |
A |
T |
7: 50,249,657 (GRCm38) |
|
probably benign |
Het |
| Nomo1 |
C |
A |
7: 46,046,937 (GRCm38) |
T293N |
probably damaging |
Het |
| Or10g1 |
T |
G |
14: 52,410,861 (GRCm38) |
T4P |
probably benign |
Het |
| Or6c211 |
A |
T |
10: 129,669,759 (GRCm38) |
C253* |
probably null |
Het |
| Or8k33 |
T |
C |
2: 86,553,584 (GRCm38) |
D180G |
possibly damaging |
Het |
| Ostc |
T |
C |
3: 130,703,508 (GRCm38) |
N80S |
probably damaging |
Het |
| Otud4 |
T |
A |
8: 79,661,073 (GRCm38) |
N300K |
possibly damaging |
Het |
| Otx1 |
A |
G |
11: 21,998,681 (GRCm38) |
|
probably benign |
Het |
| Palmd |
T |
C |
3: 116,923,751 (GRCm38) |
R366G |
possibly damaging |
Het |
| Pcdhb20 |
A |
T |
18: 37,505,780 (GRCm38) |
Q453L |
possibly damaging |
Het |
| Pcdhga9 |
T |
A |
18: 37,737,471 (GRCm38) |
Y118N |
possibly damaging |
Het |
| Pes1 |
C |
A |
11: 3,976,834 (GRCm38) |
T372K |
probably benign |
Het |
| Plcl1 |
A |
T |
1: 55,697,150 (GRCm38) |
D550V |
probably benign |
Het |
| Plekhg5 |
T |
A |
4: 152,107,503 (GRCm38) |
C433S |
probably benign |
Het |
| Plin2 |
A |
G |
4: 86,668,678 (GRCm38) |
M1T |
probably null |
Het |
| Pold1 |
C |
T |
7: 44,543,347 (GRCm38) |
|
silent |
Het |
| Ppp1r7 |
T |
A |
1: 93,357,863 (GRCm38) |
|
probably null |
Het |
| Psmb8 |
T |
C |
17: 34,200,170 (GRCm38) |
I146T |
probably damaging |
Het |
| Pzp |
A |
T |
6: 128,485,556 (GRCm38) |
|
probably null |
Het |
| Rel |
T |
C |
11: 23,761,129 (GRCm38) |
I13V |
probably benign |
Het |
| Reln |
C |
T |
5: 22,049,791 (GRCm38) |
V527I |
possibly damaging |
Het |
| Retnla |
A |
G |
16: 48,843,612 (GRCm38) |
R90G |
probably benign |
Het |
| Semp2l2b |
A |
T |
10: 22,067,379 (GRCm38) |
I234N |
probably benign |
Het |
| Shoc1 |
A |
C |
4: 59,093,850 (GRCm38) |
L226R |
probably damaging |
Het |
| Slc39a8 |
T |
A |
3: 135,886,793 (GRCm38) |
|
probably null |
Het |
| Slc5a8 |
A |
G |
10: 88,904,963 (GRCm38) |
I247V |
probably benign |
Het |
| Son |
A |
G |
16: 91,664,317 (GRCm38) |
|
probably null |
Het |
| Spcs2 |
T |
C |
7: 99,839,761 (GRCm38) |
D240G |
probably damaging |
Het |
| Stx3 |
A |
T |
19: 11,789,574 (GRCm38) |
V91D |
probably damaging |
Het |
| Taf6l |
A |
G |
19: 8,778,628 (GRCm38) |
|
probably benign |
Het |
| Tafa2 |
A |
T |
10: 123,704,365 (GRCm38) |
H42L |
possibly damaging |
Het |
| Tbc1d8 |
A |
G |
1: 39,405,317 (GRCm38) |
F187S |
probably damaging |
Het |
| Thbs1 |
C |
G |
2: 118,119,378 (GRCm38) |
N611K |
probably damaging |
Het |
| Tipin |
A |
C |
9: 64,304,327 (GRCm38) |
S232R |
probably benign |
Het |
| Tmem132b |
A |
G |
5: 125,638,268 (GRCm38) |
D347G |
probably benign |
Het |
| Tmem161a |
C |
T |
8: 70,178,915 (GRCm38) |
|
probably benign |
Het |
| Vmn2r68 |
A |
C |
7: 85,233,626 (GRCm38) |
M306R |
probably benign |
Het |
| Vwa7 |
G |
A |
17: 35,021,242 (GRCm38) |
M395I |
probably damaging |
Het |
| Ybx3 |
G |
A |
6: 131,370,413 (GRCm38) |
A253V |
probably damaging |
Het |
| Zfp53 |
A |
T |
17: 21,508,078 (GRCm38) |
E124D |
probably benign |
Het |
| Zzz3 |
T |
A |
3: 152,446,844 (GRCm38) |
|
silent |
Het |
|
| Other mutations in St5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00493:St5
|
APN |
7 |
109,527,708 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
IGL01132:St5
|
APN |
7 |
109,570,005 (GRCm38) |
splice site |
probably null |
|
|
IGL01288:St5
|
APN |
7 |
109,539,822 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01645:St5
|
APN |
7 |
109,527,634 (GRCm38) |
nonsense |
probably null |
|
|
IGL01714:St5
|
APN |
7 |
109,570,062 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02021:St5
|
APN |
7 |
109,557,372 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02302:St5
|
APN |
7 |
109,525,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02496:St5
|
APN |
7 |
109,556,235 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
IGL02795:St5
|
APN |
7 |
109,556,364 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Bucolic
|
UTSW |
7 |
109,525,548 (GRCm38) |
nonsense |
probably null |
|
|
Halcyon
|
UTSW |
7 |
109,556,793 (GRCm38) |
nonsense |
probably null |
|
|
FR4340:St5
|
UTSW |
7 |
109,556,921 (GRCm38) |
unclassified |
probably benign |
|
|
FR4737:St5
|
UTSW |
7 |
109,556,921 (GRCm38) |
unclassified |
probably benign |
|
|
PIT4466001:St5
|
UTSW |
7 |
109,531,130 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4469001:St5
|
UTSW |
7 |
109,531,130 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4472001:St5
|
UTSW |
7 |
109,531,130 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0024:St5
|
UTSW |
7 |
109,524,659 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0124:St5
|
UTSW |
7 |
109,542,511 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R0125:St5
|
UTSW |
7 |
109,556,338 (GRCm38) |
missense |
probably benign |
0.19 |
|
R0365:St5
|
UTSW |
7 |
109,538,949 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0491:St5
|
UTSW |
7 |
109,557,204 (GRCm38) |
missense |
probably benign |
0.45 |
|
R0534:St5
|
UTSW |
7 |
109,541,428 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0662:St5
|
UTSW |
7 |
109,557,426 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0743:St5
|
UTSW |
7 |
109,557,345 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0772:St5
|
UTSW |
7 |
109,542,320 (GRCm38) |
splice site |
probably null |
|
|
R0774:St5
|
UTSW |
7 |
109,542,320 (GRCm38) |
splice site |
probably null |
|
|
R0787:St5
|
UTSW |
7 |
109,525,620 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R0884:St5
|
UTSW |
7 |
109,557,345 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1518:St5
|
UTSW |
7 |
109,557,355 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1908:St5
|
UTSW |
7 |
109,525,326 (GRCm38) |
nonsense |
probably null |
|
|
R1909:St5
|
UTSW |
7 |
109,525,326 (GRCm38) |
nonsense |
probably null |
|
|
R2232:St5
|
UTSW |
7 |
109,557,207 (GRCm38) |
missense |
probably benign |
|
|
R2358:St5
|
UTSW |
7 |
109,556,446 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2847:St5
|
UTSW |
7 |
109,525,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2869:St5
|
UTSW |
7 |
109,557,430 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2869:St5
|
UTSW |
7 |
109,557,430 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2870:St5
|
UTSW |
7 |
109,557,430 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2871:St5
|
UTSW |
7 |
109,557,430 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2871:St5
|
UTSW |
7 |
109,557,430 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2873:St5
|
UTSW |
7 |
109,557,430 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2874:St5
|
UTSW |
7 |
109,557,430 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4534:St5
|
UTSW |
7 |
109,531,156 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4536:St5
|
UTSW |
7 |
109,531,156 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4559:St5
|
UTSW |
7 |
109,525,578 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4798:St5
|
UTSW |
7 |
109,557,033 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4846:St5
|
UTSW |
7 |
109,556,836 (GRCm38) |
nonsense |
probably null |
|
|
R5110:St5
|
UTSW |
7 |
109,542,490 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5181:St5
|
UTSW |
7 |
109,556,790 (GRCm38) |
missense |
probably benign |
|
|
R5268:St5
|
UTSW |
7 |
109,557,312 (GRCm38) |
missense |
probably benign |
|
|
R5403:St5
|
UTSW |
7 |
109,556,905 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5836:St5
|
UTSW |
7 |
109,541,345 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R5932:St5
|
UTSW |
7 |
109,570,016 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5937:St5
|
UTSW |
7 |
109,557,271 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R6180:St5
|
UTSW |
7 |
109,556,888 (GRCm38) |
missense |
probably benign |
0.11 |
|
R6741:St5
|
UTSW |
7 |
109,545,097 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6781:St5
|
UTSW |
7 |
109,525,304 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R7086:St5
|
UTSW |
7 |
109,525,574 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7466:St5
|
UTSW |
7 |
109,525,346 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7644:St5
|
UTSW |
7 |
109,556,793 (GRCm38) |
nonsense |
probably null |
|
|
R8354:St5
|
UTSW |
7 |
109,525,548 (GRCm38) |
nonsense |
probably null |
|
|
R8745:St5
|
UTSW |
7 |
109,557,072 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8859:St5
|
UTSW |
7 |
109,524,656 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9016:St5
|
UTSW |
7 |
109,540,435 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R9178:St5
|
UTSW |
7 |
109,557,084 (GRCm38) |
missense |
probably benign |
0.31 |
|
R9361:St5
|
UTSW |
7 |
109,527,784 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9564:St5
|
UTSW |
7 |
109,526,329 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9595:St5
|
UTSW |
7 |
109,556,766 (GRCm38) |
missense |
probably damaging |
0.96 |
|
RF062:St5
|
UTSW |
7 |
109,556,946 (GRCm38) |
unclassified |
probably benign |
|
|
X0067:St5
|
UTSW |
7 |
109,556,240 (GRCm38) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGAAGCTGGTAGCCTTGAGG -3'
(R):5'- GCTATTCTTTACTTGAGGACAGCC -3'
Sequencing Primer
(F):5'- CCTTGAGGGTACAAATGGGTG -3'
(R):5'- GTAGCCAGTGATGACCTTGAACTC -3'
|
| Posted On |
2015-02-18 |
Incidental Mutation