Incidental Mutation 'R3440:Tenm4'
ID |
267350 |
Institutional Source |
Beutler Lab
|
Gene Symbol |
Tenm4
|
Ensembl Gene |
ENSMUSG00000048078 |
Gene Name |
teneurin transmembrane protein 4 |
Synonyms |
Doc4, l7Rn3, Ten-m4, ELM2, l(7)-3Rn, Odz4 |
MMRRC Submission |
040658-MU
|
Accession Numbers |
|
Essential gene? |
Essential
(E-score: 1.000)
|
Stock # |
R3440 (G1)
|
Quality Score |
215 |
Status
|
Validated
|
Chromosome |
7 |
Chromosomal Location |
96171246-96911093 bp(+) (GRCm38) |
Type of Mutation |
missense |
DNA Base Change (assembly) |
A to T
at 96553516 bp (GRCm38)
|
Zygosity |
Heterozygous |
Amino Acid Change |
Methionine to Leucine
at position 88
(M88L)
|
Ref Sequence |
ENSEMBL: ENSMUSP00000102780
(fasta)
|
Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000107162]
[ENSMUST00000107165]
[ENSMUST00000107166]
[ENSMUST00000129737]
[ENSMUST00000138760]
|
AlphaFold |
no structure available at present |
Predicted Effect |
probably benign
Transcript: ENSMUST00000107162
AA Change: M88L
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
SMART Domains |
Protein: ENSMUSP00000102780 Gene: ENSMUSG00000048078 AA Change: M88L
Domain | Start | End | E-Value | Type |
Pfam:Ten_N
|
10 |
410 |
5.6e-195 |
PFAM |
transmembrane domain
|
411 |
433 |
N/A |
INTRINSIC |
EGF_like
|
637 |
665 |
3.43e1 |
SMART |
EGF
|
668 |
696 |
2.29e1 |
SMART |
EGF
|
701 |
730 |
1.88e-1 |
SMART |
EGF
|
733 |
762 |
1.13e1 |
SMART |
EGF
|
767 |
797 |
2.39e1 |
SMART |
EGF
|
800 |
828 |
4.32e-1 |
SMART |
EGF
|
831 |
859 |
6.02e0 |
SMART |
EGF
|
862 |
894 |
9.93e-1 |
SMART |
low complexity region
|
900 |
914 |
N/A |
INTRINSIC |
Pfam:RHS_repeat
|
2327 |
2380 |
5.5e-7 |
PFAM |
Pfam:Tox-GHH
|
2740 |
2818 |
5.2e-34 |
PFAM |
|
Predicted Effect |
probably benign
Transcript: ENSMUST00000107165
AA Change: M113L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
SMART Domains |
Protein: ENSMUSP00000102783 Gene: ENSMUSG00000048078 AA Change: M113L
Domain | Start | End | E-Value | Type |
Pfam:Ten_N
|
36 |
402 |
1.1e-171 |
PFAM |
transmembrane domain
|
403 |
425 |
N/A |
INTRINSIC |
EGF_like
|
629 |
657 |
3.43e1 |
SMART |
EGF
|
660 |
688 |
2.29e1 |
SMART |
EGF
|
693 |
722 |
1.88e-1 |
SMART |
EGF
|
725 |
754 |
1.13e1 |
SMART |
EGF
|
759 |
789 |
2.39e1 |
SMART |
EGF
|
792 |
820 |
4.32e-1 |
SMART |
EGF
|
823 |
851 |
6.02e0 |
SMART |
EGF
|
863 |
895 |
9.93e-1 |
SMART |
low complexity region
|
901 |
915 |
N/A |
INTRINSIC |
Pfam:RHS_repeat
|
2335 |
2368 |
1.6e-7 |
PFAM |
Pfam:Tox-GHH
|
2749 |
2826 |
1.8e-32 |
PFAM |
|
Predicted Effect |
probably benign
Transcript: ENSMUST00000107166
AA Change: M113L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
SMART Domains |
Protein: ENSMUSP00000102784 Gene: ENSMUSG00000048078 AA Change: M113L
Domain | Start | End | E-Value | Type |
Pfam:Ten_N
|
35 |
193 |
1.4e-83 |
PFAM |
Pfam:Ten_N
|
187 |
365 |
5e-78 |
PFAM |
transmembrane domain
|
366 |
388 |
N/A |
INTRINSIC |
EGF_like
|
592 |
620 |
3.43e1 |
SMART |
EGF
|
623 |
651 |
2.29e1 |
SMART |
EGF
|
656 |
685 |
1.88e-1 |
SMART |
EGF
|
688 |
717 |
1.13e1 |
SMART |
EGF
|
722 |
752 |
2.39e1 |
SMART |
EGF
|
755 |
783 |
4.32e-1 |
SMART |
EGF
|
786 |
814 |
6.02e0 |
SMART |
EGF
|
826 |
858 |
9.93e-1 |
SMART |
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
Pfam:RHS_repeat
|
2298 |
2351 |
3.8e-7 |
PFAM |
Pfam:Tox-GHH
|
2711 |
2789 |
3.9e-34 |
PFAM |
|
Predicted Effect |
probably benign
Transcript: ENSMUST00000129737
|
SMART Domains |
Protein: ENSMUSP00000120529 Gene: ENSMUSG00000048078
Domain | Start | End | E-Value | Type |
Pfam:Ten_N
|
60 |
125 |
6.3e-28 |
PFAM |
|
Predicted Effect |
probably benign
Transcript: ENSMUST00000138760
|
SMART Domains |
Protein: ENSMUSP00000114281 Gene: ENSMUSG00000048078
Domain | Start | End | E-Value | Type |
Pfam:Ten_N
|
35 |
100 |
6.5e-34 |
PFAM |
|
Meta Mutation Damage Score |
0.0898  |
Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.2%
|
Validation Efficiency |
97% (29/30) |
MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5. [provided by RefSeq, Oct 2016] PHENOTYPE: Various ENU-induced alleles cause prenatal lethality associated with impaired mesoderm development and lead to pleiotropic phenotypes. The most severe alleles cause failure of gastrulation and somitogenesis while the least severe one allows survival to adulthood with runting of variable penetrance. [provided by MGI curators]
|
Allele List at MGI |
|
Other mutations in this stock |
Total: 25 list
Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
4932438A13Rik |
C |
T |
3: 37,041,912 |
Q4614* |
probably null |
Het |
Abtb2 |
C |
A |
2: 103,567,232 |
A169E |
probably benign |
Het |
Adam3 |
T |
C |
8: 24,680,743 |
|
probably benign |
Het |
Agmo |
C |
T |
12: 37,243,800 |
T74I |
probably damaging |
Het |
Ano6 |
T |
C |
15: 95,967,721 |
V862A |
probably damaging |
Het |
Cavin2 |
T |
A |
1: 51,301,406 |
V414E |
probably damaging |
Het |
Clrn3 |
A |
C |
7: 135,514,125 |
Y165* |
probably null |
Het |
Cp |
A |
T |
3: 19,974,957 |
M533L |
probably benign |
Het |
Dhrs3 |
T |
A |
4: 144,920,058 |
M226K |
probably damaging |
Het |
Fignl2 |
A |
G |
15: 101,053,123 |
F426S |
unknown |
Het |
Fpr1 |
C |
T |
17: 17,877,158 |
D190N |
probably benign |
Het |
Grik3 |
C |
A |
4: 125,693,970 |
L628M |
probably damaging |
Het |
Grik3 |
T |
A |
4: 125,693,971 |
L628Q |
probably damaging |
Het |
Grin2c |
T |
A |
11: 115,250,643 |
D883V |
probably damaging |
Het |
Gtf3c6 |
T |
A |
10: 40,251,173 |
E123V |
probably null |
Het |
H2-Eb1 |
A |
G |
17: 34,309,681 |
E62G |
probably damaging |
Het |
Kif1a |
C |
T |
1: 93,036,853 |
D1334N |
possibly damaging |
Het |
Lef1 |
A |
G |
3: 131,184,758 |
D175G |
probably damaging |
Het |
Myom1 |
A |
G |
17: 71,045,663 |
|
probably null |
Het |
Olfr420 |
A |
T |
1: 174,159,180 |
M136L |
probably benign |
Het |
Pgr |
A |
T |
9: 8,922,629 |
N600I |
probably damaging |
Het |
Rab36 |
G |
A |
10: 75,044,496 |
V63I |
probably damaging |
Het |
Selp |
T |
C |
1: 164,123,775 |
F26S |
probably benign |
Het |
Tchh |
A |
T |
3: 93,445,107 |
D618V |
unknown |
Het |
Zfat |
A |
T |
15: 68,084,553 |
D1143E |
probably benign |
Het |
|
Other mutations in Tenm4 |
Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
IGL00228:Tenm4
|
APN |
7 |
96868009 |
missense |
probably benign |
0.00 |
IGL00468:Tenm4
|
APN |
7 |
96874472 |
missense |
probably damaging |
0.98 |
IGL00519:Tenm4
|
APN |
7 |
96805138 |
splice site |
probably benign |
|
IGL00979:Tenm4
|
APN |
7 |
96729391 |
missense |
probably damaging |
0.96 |
IGL01401:Tenm4
|
APN |
7 |
96874267 |
missense |
probably damaging |
1.00 |
IGL01459:Tenm4
|
APN |
7 |
96729385 |
missense |
probably damaging |
1.00 |
IGL01519:Tenm4
|
APN |
7 |
96895177 |
missense |
probably damaging |
1.00 |
IGL01545:Tenm4
|
APN |
7 |
96874303 |
missense |
probably benign |
0.00 |
IGL01579:Tenm4
|
APN |
7 |
96863502 |
missense |
probably benign |
0.00 |
IGL01587:Tenm4
|
APN |
7 |
96863502 |
missense |
probably benign |
0.00 |
IGL01625:Tenm4
|
APN |
7 |
96885358 |
missense |
probably damaging |
1.00 |
IGL01655:Tenm4
|
APN |
7 |
96553724 |
missense |
probably damaging |
1.00 |
IGL01683:Tenm4
|
APN |
7 |
96885404 |
missense |
possibly damaging |
0.84 |
IGL01728:Tenm4
|
APN |
7 |
96896064 |
missense |
probably damaging |
1.00 |
IGL01732:Tenm4
|
APN |
7 |
96895509 |
missense |
probably damaging |
1.00 |
IGL01924:Tenm4
|
APN |
7 |
96895212 |
missense |
probably damaging |
1.00 |
IGL01966:Tenm4
|
APN |
7 |
96553550 |
missense |
probably damaging |
1.00 |
IGL02177:Tenm4
|
APN |
7 |
96895662 |
missense |
probably benign |
0.40 |
IGL02207:Tenm4
|
APN |
7 |
96874116 |
missense |
possibly damaging |
0.85 |
IGL02269:Tenm4
|
APN |
7 |
96823822 |
missense |
probably damaging |
1.00 |
IGL02274:Tenm4
|
APN |
7 |
96854734 |
missense |
probably damaging |
1.00 |
IGL02375:Tenm4
|
APN |
7 |
96704137 |
missense |
possibly damaging |
0.52 |
IGL02415:Tenm4
|
APN |
7 |
96874074 |
missense |
probably damaging |
0.98 |
IGL02472:Tenm4
|
APN |
7 |
96774176 |
unclassified |
probably benign |
|
IGL02656:Tenm4
|
APN |
7 |
96885433 |
missense |
probably damaging |
1.00 |
IGL02678:Tenm4
|
APN |
7 |
96896219 |
missense |
probably damaging |
1.00 |
IGL02829:Tenm4
|
APN |
7 |
96894998 |
nonsense |
probably null |
|
IGL02863:Tenm4
|
APN |
7 |
96873706 |
missense |
probably damaging |
1.00 |
IGL03145:Tenm4
|
APN |
7 |
96842968 |
missense |
probably damaging |
0.98 |
IGL03153:Tenm4
|
APN |
7 |
96873762 |
missense |
probably damaging |
1.00 |
principium
|
UTSW |
7 |
96797481 |
missense |
probably damaging |
0.98 |
toccata
|
UTSW |
7 |
96902989 |
critical splice donor site |
probably null |
|
P0026:Tenm4
|
UTSW |
7 |
96874527 |
missense |
probably damaging |
1.00 |
R0097:Tenm4
|
UTSW |
7 |
96892926 |
missense |
probably damaging |
1.00 |
R0097:Tenm4
|
UTSW |
7 |
96892926 |
missense |
probably damaging |
1.00 |
R0140:Tenm4
|
UTSW |
7 |
96896052 |
missense |
possibly damaging |
0.78 |
R0164:Tenm4
|
UTSW |
7 |
96729340 |
splice site |
probably benign |
|
R0277:Tenm4
|
UTSW |
7 |
96694950 |
missense |
possibly damaging |
0.54 |
R0323:Tenm4
|
UTSW |
7 |
96694950 |
missense |
possibly damaging |
0.54 |
R0362:Tenm4
|
UTSW |
7 |
96772035 |
nonsense |
probably null |
|
R0381:Tenm4
|
UTSW |
7 |
96905881 |
missense |
probably damaging |
1.00 |
R0420:Tenm4
|
UTSW |
7 |
96873766 |
missense |
possibly damaging |
0.85 |
R0426:Tenm4
|
UTSW |
7 |
96777851 |
missense |
probably damaging |
1.00 |
R0513:Tenm4
|
UTSW |
7 |
96895623 |
missense |
probably benign |
0.35 |
R0624:Tenm4
|
UTSW |
7 |
96774020 |
missense |
probably damaging |
1.00 |
R0837:Tenm4
|
UTSW |
7 |
96896275 |
splice site |
probably benign |
|
R1037:Tenm4
|
UTSW |
7 |
96797481 |
missense |
probably damaging |
0.98 |
R1172:Tenm4
|
UTSW |
7 |
96848044 |
missense |
probably damaging |
1.00 |
R1422:Tenm4
|
UTSW |
7 |
96550051 |
missense |
probably damaging |
0.99 |
R1427:Tenm4
|
UTSW |
7 |
96843048 |
missense |
probably benign |
0.42 |
R1462:Tenm4
|
UTSW |
7 |
96704153 |
missense |
probably damaging |
1.00 |
R1462:Tenm4
|
UTSW |
7 |
96704153 |
missense |
probably damaging |
1.00 |
R1597:Tenm4
|
UTSW |
7 |
96902989 |
critical splice donor site |
probably null |
|
R1701:Tenm4
|
UTSW |
7 |
96902889 |
missense |
probably damaging |
1.00 |
R1707:Tenm4
|
UTSW |
7 |
96888685 |
missense |
probably damaging |
1.00 |
R1809:Tenm4
|
UTSW |
7 |
96873780 |
missense |
probably benign |
0.17 |
R1812:Tenm4
|
UTSW |
7 |
96895940 |
missense |
probably damaging |
1.00 |
R1895:Tenm4
|
UTSW |
7 |
96735808 |
missense |
probably damaging |
1.00 |
R1933:Tenm4
|
UTSW |
7 |
96895326 |
missense |
probably damaging |
1.00 |
R1946:Tenm4
|
UTSW |
7 |
96735808 |
missense |
probably damaging |
1.00 |
R2108:Tenm4
|
UTSW |
7 |
96906290 |
missense |
probably damaging |
1.00 |
R2151:Tenm4
|
UTSW |
7 |
96902847 |
missense |
probably damaging |
1.00 |
R2247:Tenm4
|
UTSW |
7 |
96906009 |
missense |
probably benign |
0.03 |
R2329:Tenm4
|
UTSW |
7 |
96895862 |
missense |
probably benign |
0.00 |
R2893:Tenm4
|
UTSW |
7 |
96894990 |
missense |
probably damaging |
1.00 |
R2990:Tenm4
|
UTSW |
7 |
96893125 |
splice site |
probably null |
|
R3409:Tenm4
|
UTSW |
7 |
96895160 |
missense |
probably damaging |
1.00 |
R3410:Tenm4
|
UTSW |
7 |
96852530 |
missense |
probably damaging |
0.99 |
R3411:Tenm4
|
UTSW |
7 |
96852530 |
missense |
probably damaging |
0.99 |
R3441:Tenm4
|
UTSW |
7 |
96553516 |
missense |
probably benign |
0.00 |
R3719:Tenm4
|
UTSW |
7 |
96863563 |
missense |
possibly damaging |
0.92 |
R3772:Tenm4
|
UTSW |
7 |
96694880 |
missense |
probably damaging |
1.00 |
R3773:Tenm4
|
UTSW |
7 |
96694880 |
missense |
probably damaging |
1.00 |
R4093:Tenm4
|
UTSW |
7 |
96895772 |
missense |
probably damaging |
1.00 |
R4439:Tenm4
|
UTSW |
7 |
96895815 |
missense |
probably benign |
0.01 |
R4441:Tenm4
|
UTSW |
7 |
96895815 |
missense |
probably benign |
0.01 |
R4510:Tenm4
|
UTSW |
7 |
96894863 |
missense |
probably benign |
|
R4511:Tenm4
|
UTSW |
7 |
96894863 |
missense |
probably benign |
|
R4543:Tenm4
|
UTSW |
7 |
96895815 |
missense |
probably benign |
0.01 |
R4645:Tenm4
|
UTSW |
7 |
96895742 |
missense |
probably damaging |
1.00 |
R4701:Tenm4
|
UTSW |
7 |
96895349 |
missense |
probably damaging |
1.00 |
R4707:Tenm4
|
UTSW |
7 |
96774046 |
missense |
probably damaging |
0.99 |
R4714:Tenm4
|
UTSW |
7 |
96894924 |
missense |
probably damaging |
1.00 |
R4742:Tenm4
|
UTSW |
7 |
96797484 |
missense |
probably damaging |
0.99 |
R4784:Tenm4
|
UTSW |
7 |
96774046 |
missense |
probably damaging |
0.99 |
R4785:Tenm4
|
UTSW |
7 |
96774046 |
missense |
probably damaging |
0.99 |
R4801:Tenm4
|
UTSW |
7 |
96906245 |
missense |
probably damaging |
0.97 |
R4802:Tenm4
|
UTSW |
7 |
96906245 |
missense |
probably damaging |
0.97 |
R4880:Tenm4
|
UTSW |
7 |
96905818 |
splice site |
probably null |
|
R5036:Tenm4
|
UTSW |
7 |
96694790 |
missense |
probably damaging |
1.00 |
R5036:Tenm4
|
UTSW |
7 |
96852561 |
missense |
probably damaging |
1.00 |
R5050:Tenm4
|
UTSW |
7 |
96895788 |
missense |
probably damaging |
1.00 |
R5103:Tenm4
|
UTSW |
7 |
96842957 |
missense |
probably damaging |
1.00 |
R5106:Tenm4
|
UTSW |
7 |
96843149 |
missense |
probably damaging |
0.99 |
R5118:Tenm4
|
UTSW |
7 |
96893086 |
missense |
probably damaging |
1.00 |
R5272:Tenm4
|
UTSW |
7 |
96874203 |
missense |
probably damaging |
0.98 |
R5282:Tenm4
|
UTSW |
7 |
96837331 |
missense |
possibly damaging |
0.90 |
R5403:Tenm4
|
UTSW |
7 |
96888827 |
missense |
probably damaging |
1.00 |
R5404:Tenm4
|
UTSW |
7 |
96894680 |
missense |
probably damaging |
1.00 |
R5567:Tenm4
|
UTSW |
7 |
96896209 |
nonsense |
probably null |
|
R5590:Tenm4
|
UTSW |
7 |
96797400 |
missense |
possibly damaging |
0.73 |
R5590:Tenm4
|
UTSW |
7 |
96797401 |
missense |
possibly damaging |
0.93 |
R5597:Tenm4
|
UTSW |
7 |
96553517 |
missense |
probably benign |
0.00 |
R5782:Tenm4
|
UTSW |
7 |
96893039 |
missense |
probably benign |
0.00 |
R5861:Tenm4
|
UTSW |
7 |
96843217 |
intron |
probably benign |
|
R5890:Tenm4
|
UTSW |
7 |
96902860 |
missense |
probably damaging |
1.00 |
R5930:Tenm4
|
UTSW |
7 |
96854719 |
missense |
probably damaging |
1.00 |
R5940:Tenm4
|
UTSW |
7 |
96845895 |
missense |
probably damaging |
1.00 |
R6012:Tenm4
|
UTSW |
7 |
96522433 |
intron |
probably benign |
|
R6060:Tenm4
|
UTSW |
7 |
96873711 |
missense |
probably damaging |
1.00 |
R6104:Tenm4
|
UTSW |
7 |
96837289 |
missense |
probably damaging |
0.97 |
R6283:Tenm4
|
UTSW |
7 |
96874494 |
missense |
probably benign |
0.33 |
R6333:Tenm4
|
UTSW |
7 |
96774124 |
missense |
probably damaging |
1.00 |
R6522:Tenm4
|
UTSW |
7 |
96843044 |
missense |
possibly damaging |
0.88 |
R6616:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R6746:Tenm4
|
UTSW |
7 |
96892860 |
missense |
probably damaging |
1.00 |
R6751:Tenm4
|
UTSW |
7 |
96845712 |
missense |
possibly damaging |
0.95 |
R6806:Tenm4
|
UTSW |
7 |
96811959 |
missense |
possibly damaging |
0.95 |
R6807:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R6807:Tenm4
|
UTSW |
7 |
96895271 |
missense |
probably damaging |
1.00 |
R6809:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R6810:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R6811:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R6853:Tenm4
|
UTSW |
7 |
96837295 |
missense |
possibly damaging |
0.94 |
R6886:Tenm4
|
UTSW |
7 |
96797392 |
missense |
possibly damaging |
0.85 |
R6920:Tenm4
|
UTSW |
7 |
96895550 |
missense |
probably damaging |
1.00 |
R6937:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R6939:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R7011:Tenm4
|
UTSW |
7 |
96896135 |
nonsense |
probably null |
|
R7033:Tenm4
|
UTSW |
7 |
96895223 |
nonsense |
probably null |
|
R7040:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R7083:Tenm4
|
UTSW |
7 |
96895349 |
missense |
probably damaging |
1.00 |
R7238:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R7239:Tenm4
|
UTSW |
7 |
96553496 |
missense |
probably benign |
0.01 |
R7239:Tenm4
|
UTSW |
7 |
96735813 |
missense |
possibly damaging |
0.47 |
R7337:Tenm4
|
UTSW |
7 |
96874126 |
missense |
probably benign |
0.44 |
R7400:Tenm4
|
UTSW |
7 |
96694803 |
missense |
probably damaging |
0.97 |
R7407:Tenm4
|
UTSW |
7 |
96773987 |
missense |
possibly damaging |
0.89 |
R7449:Tenm4
|
UTSW |
7 |
96874213 |
missense |
possibly damaging |
0.65 |
R7473:Tenm4
|
UTSW |
7 |
96774146 |
missense |
probably damaging |
1.00 |
R7477:Tenm4
|
UTSW |
7 |
96845808 |
missense |
probably damaging |
0.99 |
R7489:Tenm4
|
UTSW |
7 |
96837314 |
missense |
possibly damaging |
0.90 |
R7498:Tenm4
|
UTSW |
7 |
96848017 |
missense |
probably damaging |
1.00 |
R7562:Tenm4
|
UTSW |
7 |
96888814 |
missense |
probably damaging |
1.00 |
R7615:Tenm4
|
UTSW |
7 |
96845926 |
missense |
probably damaging |
1.00 |
R7624:Tenm4
|
UTSW |
7 |
96895985 |
missense |
possibly damaging |
0.95 |
R7626:Tenm4
|
UTSW |
7 |
96893014 |
missense |
probably damaging |
1.00 |
R7690:Tenm4
|
UTSW |
7 |
96863533 |
missense |
probably benign |
0.00 |
R7692:Tenm4
|
UTSW |
7 |
96895403 |
missense |
probably damaging |
1.00 |
R7748:Tenm4
|
UTSW |
7 |
96894702 |
missense |
probably damaging |
1.00 |
R7763:Tenm4
|
UTSW |
7 |
96895692 |
missense |
probably benign |
0.38 |
R7792:Tenm4
|
UTSW |
7 |
96774014 |
missense |
possibly damaging |
0.54 |
R7855:Tenm4
|
UTSW |
7 |
96873874 |
missense |
probably damaging |
1.00 |
R7868:Tenm4
|
UTSW |
7 |
96906380 |
missense |
possibly damaging |
0.79 |
R7878:Tenm4
|
UTSW |
7 |
96852357 |
missense |
probably damaging |
1.00 |
R7997:Tenm4
|
UTSW |
7 |
96874305 |
missense |
probably benign |
0.44 |
R8017:Tenm4
|
UTSW |
7 |
96704041 |
missense |
probably damaging |
1.00 |
R8019:Tenm4
|
UTSW |
7 |
96704041 |
missense |
probably damaging |
1.00 |
R8054:Tenm4
|
UTSW |
7 |
96729346 |
splice site |
probably benign |
|
R8061:Tenm4
|
UTSW |
7 |
96852456 |
missense |
probably damaging |
1.00 |
R8108:Tenm4
|
UTSW |
7 |
96854728 |
missense |
probably benign |
0.39 |
R8140:Tenm4
|
UTSW |
7 |
96895176 |
missense |
probably damaging |
1.00 |
R8214:Tenm4
|
UTSW |
7 |
96895407 |
missense |
probably damaging |
1.00 |
R8258:Tenm4
|
UTSW |
7 |
96867991 |
missense |
probably damaging |
1.00 |
R8259:Tenm4
|
UTSW |
7 |
96867991 |
missense |
probably damaging |
1.00 |
R8364:Tenm4
|
UTSW |
7 |
96772106 |
critical splice donor site |
probably null |
|
R8542:Tenm4
|
UTSW |
7 |
96811932 |
missense |
probably damaging |
0.99 |
R8669:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8670:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8683:Tenm4
|
UTSW |
7 |
96902857 |
missense |
probably damaging |
0.99 |
R8691:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8692:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8714:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8716:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8735:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8736:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8737:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8738:Tenm4
|
UTSW |
7 |
96873840 |
missense |
probably damaging |
1.00 |
R8738:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8739:Tenm4
|
UTSW |
7 |
96905941 |
missense |
probably benign |
|
R8776:Tenm4
|
UTSW |
7 |
96895032 |
missense |
probably damaging |
1.00 |
R8776-TAIL:Tenm4
|
UTSW |
7 |
96895032 |
missense |
probably damaging |
1.00 |
R8777:Tenm4
|
UTSW |
7 |
96896037 |
missense |
probably damaging |
1.00 |
R8777-TAIL:Tenm4
|
UTSW |
7 |
96896037 |
missense |
probably damaging |
1.00 |
R8817:Tenm4
|
UTSW |
7 |
96874128 |
missense |
probably benign |
0.01 |
R8851:Tenm4
|
UTSW |
7 |
96852503 |
missense |
probably damaging |
1.00 |
R8913:Tenm4
|
UTSW |
7 |
96702745 |
splice site |
probably benign |
|
R8977:Tenm4
|
UTSW |
7 |
96811970 |
missense |
probably damaging |
1.00 |
R9100:Tenm4
|
UTSW |
7 |
96845854 |
missense |
probably damaging |
1.00 |
R9136:Tenm4
|
UTSW |
7 |
96823918 |
missense |
possibly damaging |
0.69 |
R9163:Tenm4
|
UTSW |
7 |
96823873 |
missense |
probably damaging |
1.00 |
R9188:Tenm4
|
UTSW |
7 |
96772027 |
missense |
probably damaging |
1.00 |
R9195:Tenm4
|
UTSW |
7 |
96892919 |
missense |
probably damaging |
1.00 |
R9217:Tenm4
|
UTSW |
7 |
96885439 |
missense |
probably damaging |
1.00 |
R9344:Tenm4
|
UTSW |
7 |
96896145 |
missense |
probably damaging |
1.00 |
R9414:Tenm4
|
UTSW |
7 |
96896160 |
missense |
probably benign |
|
R9466:Tenm4
|
UTSW |
7 |
96550045 |
missense |
possibly damaging |
0.79 |
R9559:Tenm4
|
UTSW |
7 |
96823849 |
missense |
probably benign |
|
R9626:Tenm4
|
UTSW |
7 |
96896138 |
missense |
probably damaging |
1.00 |
R9673:Tenm4
|
UTSW |
7 |
96867989 |
missense |
probably damaging |
1.00 |
R9676:Tenm4
|
UTSW |
7 |
96895431 |
missense |
probably damaging |
1.00 |
R9678:Tenm4
|
UTSW |
7 |
96737412 |
missense |
possibly damaging |
0.94 |
R9775:Tenm4
|
UTSW |
7 |
96906554 |
missense |
possibly damaging |
0.92 |
R9790:Tenm4
|
UTSW |
7 |
96888839 |
missense |
probably damaging |
1.00 |
R9791:Tenm4
|
UTSW |
7 |
96888839 |
missense |
probably damaging |
1.00 |
R9803:Tenm4
|
UTSW |
7 |
96553478 |
missense |
probably damaging |
1.00 |
X0021:Tenm4
|
UTSW |
7 |
96873909 |
nonsense |
probably null |
|
X0026:Tenm4
|
UTSW |
7 |
96868087 |
missense |
probably damaging |
0.98 |
X0066:Tenm4
|
UTSW |
7 |
96848030 |
missense |
probably damaging |
1.00 |
X0066:Tenm4
|
UTSW |
7 |
96894794 |
missense |
probably damaging |
1.00 |
Z1176:Tenm4
|
UTSW |
7 |
96905914 |
missense |
probably benign |
0.00 |
Z1177:Tenm4
|
UTSW |
7 |
96863585 |
missense |
probably damaging |
0.96 |
|
Predicted Primers |
PCR Primer
(F):5'- TGGCACTTGGCTAGAGAAGG -3'
(R):5'- GTAACCCCGTGTAACCAACG -3'
Sequencing Primer
(F):5'- CTTGGCTAGAGAAGGAGGGGTG -3'
(R):5'- GAGCCACTCACCGGTTTCTG -3'
|
Posted On |
2015-02-18 |